Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

John Kappler to Molecular Sequence Data

This is a "connection" page, showing publications John Kappler has written about Molecular Sequence Data.

 
Connection Strength
 
 
 
1.194
 
  1. Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23.
    View in: PubMed
    Score: 0.088
  2. Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
    View in: PubMed
    Score: 0.067
  3. Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10978-83.
    View in: PubMed
    Score: 0.061
  4. Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11893-7.
    View in: PubMed
    Score: 0.054
  5. Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol Rev. 2006 Apr; 210:156-70.
    View in: PubMed
    Score: 0.046
  6. Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2476-81.
    View in: PubMed
    Score: 0.042
  7. Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. PLoS Biol. 2004 Apr; 2(4):E90.
    View in: PubMed
    Score: 0.040
  8. Liu X, Dai S, Crawford F, Fruge R, Marrack P, Kappler J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8820-5.
    View in: PubMed
    Score: 0.035
  9. Wilson N, Fremont D, Marrack P, Kappler J. Mutations changing the kinetics of class II MHC peptide exchange. Immunity. 2001 May; 14(5):513-22.
    View in: PubMed
    Score: 0.032
  10. Kappler J, Franken S, Junghans U, Hoffmann R, Linke T, M?ller HW, Koch KW. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. Biochem Biophys Res Commun. 2000 May 10; 271(2):287-91.
    View in: PubMed
    Score: 0.030
  11. White J, Crawford F, Fremont D, Marrack P, Kappler J. Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. J Immunol. 1999 Mar 01; 162(5):2671-6.
    View in: PubMed
    Score: 0.028
  12. Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 1998 Sep; 9(3):385-93.
    View in: PubMed
    Score: 0.027
  13. Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 1998 Jun; 8(6):675-82.
    View in: PubMed
    Score: 0.027
  14. Liu CP, Crawford F, Marrack P, Kappler J. T cell positive selection by a high density, low affinity ligand. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4522-6.
    View in: PubMed
    Score: 0.026
  15. Seibel JL, Wilson N, Kozono H, Marrack P, Kappler JW. Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition. J Exp Med. 1997 Jun 02; 185(11):1919-27.
    View in: PubMed
    Score: 0.025
  16. Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 1996 May 17; 272(5264):1001-4.
    View in: PubMed
    Score: 0.023
  17. Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 1995 Aug; 3(2):187-96.
    View in: PubMed
    Score: 0.022
  18. Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunol. 2016 Jan; 9(1):218-28.
    View in: PubMed
    Score: 0.022
  19. Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4429-34.
    View in: PubMed
    Score: 0.021
  20. Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14840-5.
    View in: PubMed
    Score: 0.021
  21. Kappler J, White J, Kozono H, Clements J, Marrack P. Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8462-6.
    View in: PubMed
    Score: 0.020
  22. Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994 May 12; 369(6476):151-4.
    View in: PubMed
    Score: 0.020
  23. Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP. Identification of multiple public TCR repertoires in chronic beryllium disease. J Immunol. 2014 May 15; 192(10):4571-80.
    View in: PubMed
    Score: 0.020
  24. Winslow GM, Marrack P, Kappler JW. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1994 Apr; 1(1):23-33.
    View in: PubMed
    Score: 0.020
  25. White J, Pullen A, Choi K, Marrack P, Kappler JW. Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor. J Exp Med. 1993 Jan 01; 177(1):119-25.
    View in: PubMed
    Score: 0.018
  26. Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18517-22.
    View in: PubMed
    Score: 0.018
  27. Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. J Exp Med. 1992 Mar 01; 175(3):847-52.
    View in: PubMed
    Score: 0.017
  28. Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med. 1992 Feb 01; 175(2):387-96.
    View in: PubMed
    Score: 0.017
  29. Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. J Immunol. 2011 Oct 01; 187(7):3694-703.
    View in: PubMed
    Score: 0.017
  30. MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
    View in: PubMed
    Score: 0.016
  31. Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 1990 Aug 02; 346(6283):471-3.
    View in: PubMed
    Score: 0.015
  32. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 Jun 01; 248(4959):1066.
    View in: PubMed
    Score: 0.015
  33. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 May 11; 248(4956):705-11.
    View in: PubMed
    Score: 0.015
  34. Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31.
    View in: PubMed
    Score: 0.015
  35. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8941-5.
    View in: PubMed
    Score: 0.015
  36. McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol. 2009 Oct 01; 183(7):4403-14.
    View in: PubMed
    Score: 0.014
  37. Wade T, Bill J, Marrack PC, Palmer E, Kappler JW. Molecular basis for the nonexpression of V beta 17 in some strains of mice. J Immunol. 1988 Sep 15; 141(6):2165-7.
    View in: PubMed
    Score: 0.014
  38. Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11565-70.
    View in: PubMed
    Score: 0.010
  39. Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nat Immunol. 2003 Oct; 4(10):974-81.
    View in: PubMed
    Score: 0.010
  40. Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L, Pan CH, Martin WE, Murphy RC, Shu HB, Dai S, Zhang G. Ligand-receptor binding revealed by the TNF family member TALL-1. Nature. 2003 May 01; 423(6935):49-56.
    View in: PubMed
    Score: 0.009
  41. Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G. Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell. 2002 Feb 08; 108(3):383-94.
    View in: PubMed
    Score: 0.009
  42. Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol. 2001 May; 2(5):397-402.
    View in: PubMed
    Score: 0.008
  43. Kersh GJ, Miley MJ, Nelson CA, Grakoui A, Horvath S, Donermeyer DL, Kappler J, Allen PM, Fremont DH. Structural and functional consequences of altering a peptide MHC anchor residue. J Immunol. 2001 Mar 01; 166(5):3345-54.
    View in: PubMed
    Score: 0.008
  44. Jackisch BO, Hausser H, Schaefer L, Kappler J, M?ller HW, Kresse H. Alternative exon usage of rat septins. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):180-8.
    View in: PubMed
    Score: 0.008
  45. Liu CP, Parker D, Kappler J, Marrack P. Selection of antigen-specific T cells by a single IEk peptide combination. J Exp Med. 1997 Nov 03; 186(9):1441-50.
    View in: PubMed
    Score: 0.006
  46. Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
    View in: PubMed
    Score: 0.006
  47. Ku CC, Kappler J, Marrack P. Characteristics and maintenance of CD8+ T-cell clones found in old mice. Mech Ageing Dev. 1997 Mar; 94(1-3):41-53.
    View in: PubMed
    Score: 0.006
  48. Scherer MT, Ignatowicz L, Pullen A, Kappler J, Marrack P. The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med. 1995 Nov 01; 182(5):1493-504.
    View in: PubMed
    Score: 0.006
  49. Ignatowicz L, Winslow G, Bill J, Kappler J, Marrack P. Cell surface expression of class II MHC proteins bound by a single peptide. J Immunol. 1995 Apr 15; 154(8):3852-62.
    View in: PubMed
    Score: 0.005
  50. Donahue JP, Ricalton NS, Behrendt CE, Rittershaus C, Calaman S, Marrack P, Kappler JW, Kotzin BL. Genetic analysis of low V beta 3 expression in humans. J Exp Med. 1994 May 01; 179(5):1701-6.
    View in: PubMed
    Score: 0.005
  51. McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2086-90.
    View in: PubMed
    Score: 0.005
  52. Ignatowicz L, Kappler JW, Marrack P, Scherer MT. Identification of two V beta 7-specific viral superantigens. J Immunol. 1994 Jan 01; 152(1):65-71.
    View in: PubMed
    Score: 0.005
  53. Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II. J Exp Med. 1993 Dec 01; 178(6):2173-83.
    View in: PubMed
    Score: 0.005
  54. Hugo P, Kappler JW, Marrack PC. Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? Immunol Rev. 1993 Oct; 135:133-55.
    View in: PubMed
    Score: 0.005
  55. Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ. Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun. 1993 Aug; 61(8):3175-83.
    View in: PubMed
    Score: 0.005
  56. Scherer MT, Ignatowicz L, Winslow GM, Kappler JW, Marrack P. Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol. 1993; 9:101-28.
    View in: PubMed
    Score: 0.005
  57. Kotzin BL, Leung DY, Kappler J, Marrack P. Superantigens and their potential role in human disease. Adv Immunol. 1993; 54:99-166.
    View in: PubMed
    Score: 0.005
  58. Pullen AM, Choi Y, Kushnir E, Kappler J, Marrack P. The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med. 1992 Jan 01; 175(1):41-7.
    View in: PubMed
    Score: 0.004
  59. McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cell Immunol. 1991 Dec; 138(2):413-22.
    View in: PubMed
    Score: 0.004
  60. Herman A, Labrecque N, Thibodeau J, Marrack P, Kappler JW, Sekaly RP. Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):9954-8.
    View in: PubMed
    Score: 0.004
  61. Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8357-61.
    View in: PubMed
    Score: 0.004
  62. Paliard X, West SG, Lafferty JA, Clements JR, Kappler JW, Marrack P, Kotzin BL. Evidence for the effects of a superantigen in rheumatoid arthritis. Science. 1991 Jul 19; 253(5017):325-9.
    View in: PubMed
    Score: 0.004
  63. Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 1991 Mar 21; 350(6315):203-7.
    View in: PubMed
    Score: 0.004
  64. Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 1990 Sep 21; 62(6):1115-21.
    View in: PubMed
    Score: 0.004
  65. Pullen AM, Potts W, Wakeland EK, Kappler J, Marrack P. Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J Exp Med. 1990 Jan 01; 171(1):49-62.
    View in: PubMed
    Score: 0.004
  66. White J, Blackman M, Bill J, Kappler J, Marrack P, Gold DP, Born W. Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol. 1989 Sep 15; 143(6):1822-5.
    View in: PubMed
    Score: 0.004
  67. Yague J, Blackman M, Born W, Marrack P, Kappler J, Palmer E. The structure of V alpha and J alpha segments in the mouse. Nucleic Acids Res. 1988 Dec 09; 16(23):11355-64.
    View in: PubMed
    Score: 0.003
  68. Born W, Miles C, White J, O'Brien R, Freed JH, Marrack P, Kappler J, Kubo RT. Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins. Nature. 1987 Dec 10-16; 330(6148):572-4.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)