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Connection

John Kappler to Mice

This is a "connection" page, showing publications John Kappler has written about Mice.

 
Connection Strength
 
 
 
1.866
 
  1. Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor. Elife. 2017 11 17; 6.
    View in: PubMed
    Score: 0.042
  2. Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):E5608-17.
    View in: PubMed
    Score: 0.038
  3. Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23.
    View in: PubMed
    Score: 0.036
  4. Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. PLoS One. 2015; 10(8):e0136613.
    View in: PubMed
    Score: 0.036
  5. Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR a genes in an Ikaros null thymoma cell line. Eur J Immunol. 2013 Feb; 43(2):521-32.
    View in: PubMed
    Score: 0.030
  6. Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
    View in: PubMed
    Score: 0.027
  7. Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 2011 Jul 22; 35(1):23-33.
    View in: PubMed
    Score: 0.027
  8. Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10978-83.
    View in: PubMed
    Score: 0.025
  9. Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol. 2009 Dec; 7(12):e1000253.
    View in: PubMed
    Score: 0.024
  10. Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7951-6.
    View in: PubMed
    Score: 0.023
  11. Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Curr Opin Immunol. 2008 Apr; 20(2):203-7.
    View in: PubMed
    Score: 0.021
  12. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203.
    View in: PubMed
    Score: 0.021
  13. Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat Immunol. 2006 Nov; 7(11):1191-9.
    View in: PubMed
    Score: 0.019
  14. Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol Rev. 2006 Apr; 210:156-70.
    View in: PubMed
    Score: 0.019
  15. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol. 2006 Mar 01; 176(5):2683-90.
    View in: PubMed
    Score: 0.018
  16. Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 2005 Jul 29; 122(2):247-60.
    View in: PubMed
    Score: 0.018
  17. Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2476-81.
    View in: PubMed
    Score: 0.017
  18. Brown AJ, White J, Shaw L, Gross J, Slabodkin A, Kushner E, Greiff V, Matsuda J, Gapin L, Scott-Browne J, Kappler J, Marrack P. MHC heterozygosity limits T cell receptor variability in CD4 T cells. Sci Immunol. 2024 07 12; 9(97):eado5295.
    View in: PubMed
    Score: 0.016
  19. Smith JA, Yuen BTK, Purtha W, Balolong JM, Phipps JD, Crawford F, Bluestone JA, Kappler JW, Anderson MS. Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Proc Natl Acad Sci U S A. 2024 May 14; 121(20):e2320268121.
    View in: PubMed
    Score: 0.016
  20. Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. PLoS Biol. 2004 Apr; 2(4):E90.
    View in: PubMed
    Score: 0.016
  21. Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep; 19(3):341-52.
    View in: PubMed
    Score: 0.016
  22. Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. J Exp Med. 2003 Mar 03; 197(5):567-74.
    View in: PubMed
    Score: 0.015
  23. Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). J Exp Med. 2002 Apr 15; 195(8):1043-52.
    View in: PubMed
    Score: 0.014
  24. Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes. 2021 11; 70(11):2580-2594.
    View in: PubMed
    Score: 0.014
  25. Ramos SA, Morton JJ, Yadav P, Reed B, Alizadeh SI, Shilleh AH, Perrenoud L, Jaggers J, Kappler J, Jimeno A, Russ HA. Generation of functional human thymic cells from induced pluripotent stem cells. J Allergy Clin Immunol. 2022 02; 149(2):767-781.e6.
    View in: PubMed
    Score: 0.013
  26. Wei P, Jordan KR, Buhrman JD, Lei J, Deng H, Marrack P, Dai S, Kappler JW, Slansky JE, Yin L. Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
    View in: PubMed
    Score: 0.013
  27. Falta MT, Crawford JC, Tinega AN, Landry LG, Crawford F, Mack DG, Martin AK, Atif SM, Li L, Santos RG, Nakayama M, Kappler JW, Maier LA, Thomas PG, Pinilla C, Fontenot AP. Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation. J Clin Invest. 2021 05 03; 131(9).
    View in: PubMed
    Score: 0.013
  28. Wilson N, Fremont D, Marrack P, Kappler J. Mutations changing the kinetics of class II MHC peptide exchange. Immunity. 2001 May; 14(5):513-22.
    View in: PubMed
    Score: 0.013
  29. Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
    View in: PubMed
    Score: 0.013
  30. Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Curr Opin Immunol. 2000 Apr; 12(2):206-9.
    View in: PubMed
    Score: 0.012
  31. Lee S, Liu H, Hill R, Chen C, Hong X, Crawford F, Kingsley M, Zhang Q, Liu X, Chen Z, Lengeling A, Bernt KM, Marrack P, Kappler J, Zhou Q, Li CY, Xue Y, Hansen K, Zhang G. JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife. 2020 02 12; 9.
    View in: PubMed
    Score: 0.012
  32. Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):291-6.
    View in: PubMed
    Score: 0.012
  33. Cepeda JR, Sekhar NS, Han J, Xiong W, Zhang N, Yu L, Dai S, Davidson HW, Kappler JW, An Z, Zhang L. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. MAbs. 2020 Jan-Dec; 12(1):1836714.
    View in: PubMed
    Score: 0.012
  34. Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22252-22261.
    View in: PubMed
    Score: 0.012
  35. Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9781-6.
    View in: PubMed
    Score: 0.012
  36. Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
    View in: PubMed
    Score: 0.011
  37. White J, Crawford F, Fremont D, Marrack P, Kappler J. Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. J Immunol. 1999 Mar 01; 162(5):2671-6.
    View in: PubMed
    Score: 0.011
  38. Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 1998 Sep; 9(3):385-93.
    View in: PubMed
    Score: 0.011
  39. Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 1998 Jun; 8(6):675-82.
    View in: PubMed
    Score: 0.011
  40. Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep. 2018 02 19; 8(1):3275.
    View in: PubMed
    Score: 0.011
  41. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167.
    View in: PubMed
    Score: 0.010
  42. Seibel JL, Wilson N, Kozono H, Marrack P, Kappler JW. Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition. J Exp Med. 1997 Jun 02; 185(11):1919-27.
    View in: PubMed
    Score: 0.010
  43. Hamad AR, Marrack P, Kappler JW. Transcytosis of staphylococcal superantigen toxins. J Exp Med. 1997 Apr 21; 185(8):1447-54.
    View in: PubMed
    Score: 0.010
  44. Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol. 1997 Apr; 9(2):250-5.
    View in: PubMed
    Score: 0.010
  45. Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFN? in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. PLoS One. 2016; 11(11):e0166322.
    View in: PubMed
    Score: 0.010
  46. Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. J Immunol. 2016 08 15; 197(4):1221-30.
    View in: PubMed
    Score: 0.009
  47. Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 1996 May 17; 272(5264):1001-4.
    View in: PubMed
    Score: 0.009
  48. Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 1995 Aug; 3(2):187-96.
    View in: PubMed
    Score: 0.009
  49. Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunol. 2016 Jan; 9(1):218-28.
    View in: PubMed
    Score: 0.009
  50. Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. J Immunol. 2015 Jul 01; 195(1):71-9.
    View in: PubMed
    Score: 0.009
  51. Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4429-34.
    View in: PubMed
    Score: 0.009
  52. Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science. 2014 Oct 17; 346(6207):363-8.
    View in: PubMed
    Score: 0.008
  53. Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14840-5.
    View in: PubMed
    Score: 0.008
  54. Kappler J, White J, Kozono H, Clements J, Marrack P. Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8462-6.
    View in: PubMed
    Score: 0.008
  55. Hamad AR, Herman A, Marrack P, Kappler JW. Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B. J Exp Med. 1994 Aug 01; 180(2):615-21.
    View in: PubMed
    Score: 0.008
  56. Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8553-8.
    View in: PubMed
    Score: 0.008
  57. Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994 May 12; 369(6476):151-4.
    View in: PubMed
    Score: 0.008
  58. David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
    View in: PubMed
    Score: 0.008
  59. Winslow GM, Marrack P, Kappler JW. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1994 Apr; 1(1):23-33.
    View in: PubMed
    Score: 0.008
  60. Zhang L, Crawford F, Yu L, Michels A, Nakayama M, Davidson HW, Kappler JW, Eisenbarth GS. Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2656-61.
    View in: PubMed
    Score: 0.008
  61. Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E119-28.
    View in: PubMed
    Score: 0.008
  62. Buhrman JD, Jordan KR, Munson DJ, Moore BL, Kappler JW, Slansky JE. Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor. J Biol Chem. 2013 Nov 15; 288(46):33213-25.
    View in: PubMed
    Score: 0.008
  63. Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3216-24.
    View in: PubMed
    Score: 0.008
  64. Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. J Exp Med. 2013 Jul 01; 210(7):1403-18.
    View in: PubMed
    Score: 0.008
  65. Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. PLoS One. 2013; 8(4):e61775.
    View in: PubMed
    Score: 0.008
  66. Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunol Res. 2013 Mar; 55(1-3):210-6.
    View in: PubMed
    Score: 0.007
  67. McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1122-31.
    View in: PubMed
    Score: 0.007
  68. Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. PLoS One. 2013; 8(2):e57435.
    View in: PubMed
    Score: 0.007
  69. Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions. Immunol Rev. 1993 Feb; 131:79-92.
    View in: PubMed
    Score: 0.007
  70. Marrack P, McCormack J, Callahan J, Ignatowicz L, Kappler J. T cell tolerance. Giles F. Filley Lecture. Chest. 1993 Feb; 103(2 Suppl):76S-78S.
    View in: PubMed
    Score: 0.007
  71. Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. PLoS One. 2013; 8(1):e53789.
    View in: PubMed
    Score: 0.007
  72. White J, Pullen A, Choi K, Marrack P, Kappler JW. Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor. J Exp Med. 1993 Jan 01; 177(1):119-25.
    View in: PubMed
    Score: 0.007
  73. Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60.
    View in: PubMed
    Score: 0.007
  74. Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol. 2012 Jul 19; 13(8):705-6.
    View in: PubMed
    Score: 0.007
  75. Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. J Exp Med. 1992 Mar 01; 175(3):847-52.
    View in: PubMed
    Score: 0.007
  76. Jordan KR, Buhrman JD, Sprague J, Moore BL, Gao D, Kappler JW, Slansky JE. TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines. Cancer Immunol Immunother. 2012 Oct; 61(10):1627-38.
    View in: PubMed
    Score: 0.007
  77. Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med. 1992 Feb 01; 175(2):387-96.
    View in: PubMed
    Score: 0.007
  78. Zhang L, Stadinski BD, Michels A, Kappler JW, Eisenbarth GS. Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice. Diabetes Metab Res Rev. 2011 Nov; 27(8):784-9.
    View in: PubMed
    Score: 0.007
  79. Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. J Immunol. 2011 Oct 01; 187(7):3694-703.
    View in: PubMed
    Score: 0.007
  80. Kenyon KD, Cole C, Crawford F, Kappler JW, Thurman JM, Bratton DL, Boackle SA, Henson PM. IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity. J Immunol. 2011 Sep 01; 187(5):2101-11.
    View in: PubMed
    Score: 0.007
  81. Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c? B-cell population is important for the development of autoimmunity. Blood. 2011 Aug 04; 118(5):1305-15.
    View in: PubMed
    Score: 0.007
  82. Pullen AM, Bill J, Kubo RT, Marrack P, Kappler JW. Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta. J Exp Med. 1991 May 01; 173(5):1183-92.
    View in: PubMed
    Score: 0.007
  83. MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7914-9.
    View in: PubMed
    Score: 0.007
  84. Marrack P, Kushnir E, Kappler J. A maternally inherited superantigen encoded by a mammary tumour virus. Nature. 1991 Feb 07; 349(6309):524-6.
    View in: PubMed
    Score: 0.006
  85. MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
    View in: PubMed
    Score: 0.006
  86. Munks MW, McKee AS, Macleod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P. Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo. Blood. 2010 Dec 09; 116(24):5191-9.
    View in: PubMed
    Score: 0.006
  87. Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 1990 Aug 02; 346(6283):471-3.
    View in: PubMed
    Score: 0.006
  88. Pullen AM, Wade T, Marrack P, Kappler JW. Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell. 1990 Jun 29; 61(7):1365-74.
    View in: PubMed
    Score: 0.006
  89. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 May 11; 248(4956):705-11.
    View in: PubMed
    Score: 0.006
  90. Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. J Immunol. 2010 May 01; 184(9):4592-5.
    View in: PubMed
    Score: 0.006
  91. Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30.
    View in: PubMed
    Score: 0.006
  92. Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31.
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    Score: 0.006
  93. Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmun Rev. 2010 May; 9(7):494-8.
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    Score: 0.006
  94. Marrack P, Blackman M, Kushnir E, Kappler J. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med. 1990 Feb 01; 171(2):455-64.
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    Score: 0.006
  95. Jordan KR, McMahan RH, Kemmler CB, Kappler JW, Slansky JE. Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4652-7.
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    Score: 0.006
  96. Marrack P, Kappler J. T cell tolerance. Semin Immunol. 1990 Jan; 2(1):45-9.
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    Score: 0.006
  97. Pullen AM, Potts W, Wakeland EK, Kappler J, Marrack P. Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J Exp Med. 1990 Jan 01; 171(1):49-62.
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    Score: 0.006
  98. Burgert HG, White J, Weltzien HU, Marrack P, Kappler JW. Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner. J Exp Med. 1989 Dec 01; 170(6):1887-904.
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    Score: 0.006
  99. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8941-5.
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    Score: 0.006
  100. Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 1989 Sep 22; 58(6):1047-54.
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    Score: 0.006
  101. McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol. 2009 Oct 01; 183(7):4403-14.
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    Score: 0.006
  102. Pullen AM, Marrack P, Kappler JW. Evidence that Mls-2 antigens which delete V beta 3+ T cells are controlled by multiple genes. J Immunol. 1989 May 01; 142(9):3033-7.
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    Score: 0.006
  103. Kappler JW, Kushnir E, Marrack P. Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype. J Exp Med. 1989 May 01; 169(5):1533-41.
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    Score: 0.006
  104. Blackman MA, Marrack P, Kappler J. Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science. 1989 Apr 14; 244(4901):214-7.
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    Score: 0.006
  105. Marrack P, McCormack J, Kappler J. Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium. Nature. 1989 Apr 06; 338(6215):503-5.
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    Score: 0.006
  106. Jordan KR, Crawford F, Kappler JW, Slansky JE. Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins. Curr Protoc Immunol. 2009 Apr; Chapter 2:2.15.1-2.15.23.
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    Score: 0.006
  107. Desbien AL, Kappler JW, Marrack P. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5663-8.
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    Score: 0.006
  108. Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 2009 Apr 23; 458(7241):1043-6.
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    Score: 0.006
  109. Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. Int Immunol. 2009 Apr; 21(4):339-48.
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    Score: 0.006
  110. Kappler JW, Pullen A, Callahan J, Choi Y, Herman A, White J, Potts W, Wakeland E, Marrack P. Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:401-7.
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    Score: 0.006
  111. Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:105-10.
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    Score: 0.006
  112. Carbone AM, Marrack P, Kappler JW. Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors. Science. 1988 Nov 25; 242(4882):1174-6.
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    Score: 0.006
  113. O'Brien RL, Marrack P, Storb U, Kappler JW. B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells. J Immunol. 1988 Nov 15; 141(10):3335-41.
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    Score: 0.006
  114. Pullen AM, Marrack P, Kappler JW. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature. 1988 Oct 27; 335(6193):796-801.
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    Score: 0.006
  115. Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nat Immunol. 2008 Dec; 9(12):1356-63.
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    Score: 0.006
  116. Marrack P, Kappler J. The T-cell repertoire for antigen and MHC. Immunol Today. 1988 Oct; 9(10):308-15.
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    Score: 0.006
  117. Wade T, Bill J, Marrack PC, Palmer E, Kappler JW. Molecular basis for the nonexpression of V beta 17 in some strains of mice. J Immunol. 1988 Sep 15; 141(6):2165-7.
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    Score: 0.006
  118. MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14521-6.
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    Score: 0.005
  119. Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12997-3002.
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    Score: 0.005
  120. Carbone AM, Marrack P, Kappler JW. Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression. J Immunol. 1988 Aug 15; 141(4):1369-75.
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    Score: 0.005
  121. Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 1988 May 20; 53(4):627-34.
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    Score: 0.005
  122. Marrack P, Kappler J. T cells can distinguish between allogeneic major histocompatibility complex products on different cell types. Nature. 1988 Apr 28; 332(6167):840-3.
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    Score: 0.005
  123. Marrack P, Kushnir E, Born W, McDuffie M, Kappler J. The development of helper T cell precursors in mouse thymus. J Immunol. 1988 Apr 15; 140(8):2508-14.
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    Score: 0.005
  124. McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol. 2008 May; 20(5):659-69.
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    Score: 0.005
  125. Kappler JW, Staerz U, White J, Marrack PC. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature. 1988 Mar 03; 332(6159):35-40.
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    Score: 0.005
  126. Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE. Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity. J Immunol. 2008 Jan 01; 180(1):188-97.
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    Score: 0.005
  127. McDuffie M, Roehm N, Born W, Marrack P, Kappler JW. T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire. Transplant Proc. 1987 Dec; 19(6 Suppl 7):111-6.
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    Score: 0.005
  128. Marrack P, Kappler J. The T cell receptor. Science. 1987 Nov 20; 238(4830):1073-9.
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    Score: 0.005
  129. Hannum C, Marrack P, Kubo R, Kappler J. Thymocytes with the predicted properties of pre-T cells. J Exp Med. 1987 Oct 01; 166(4):874-89.
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    Score: 0.005
  130. Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. J Immunol. 2007 Sep 15; 179(6):3417-24.
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    Score: 0.005
  131. Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol. 2007 Oct; 8(10):1105-13.
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    Score: 0.005
  132. Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J, et al. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 1987 Aug 13-19; 328(6131):626-9.
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    Score: 0.005
  133. Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest. 2007 May; 117(5):1270-81.
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    Score: 0.005
  134. Kappler JW, Wade T, White J, Kushnir E, Blackman M, Bill J, Roehm N, Marrack P. A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell. 1987 Apr 24; 49(2):263-71.
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    Score: 0.005
  135. Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell. 1987 Apr 24; 49(2):273-80.
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    Score: 0.005
  136. Marrack P, McDuffie M, Born W, Blackman M, Hannum C, Kappler J. The T cell receptor: its repertoire and role in thymocyte development. Adv Exp Med Biol. 1987; 213:1-12.
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    Score: 0.005
  137. Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. J Exp Med. 2006 Dec 25; 203(13):2953-61.
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    Score: 0.005
  138. Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 2006 Dec; 25(6):929-40.
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    Score: 0.005
  139. McDuffie M, Born W, Marrack P, Kappler J. The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8728-32.
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    Score: 0.005
  140. Born W, Rathbun G, Tucker P, Marrack P, Kappler J. Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. Science. 1986 Oct 24; 234(4775):479-82.
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    Score: 0.005
  141. Jørgensen TN, Thurman J, Izui S, Falta MT, Metzger TE, Flannery SA, Kappler J, Marrack P, Kotzin BL. Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice. Genes Immun. 2006 Oct; 7(7):555-67.
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    Score: 0.005
  142. Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12063-8.
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    Score: 0.005
  143. Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. J Exp Med. 2006 May 15; 203(5):1147-52.
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    Score: 0.005
  144. Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. J Exp Med. 2006 Mar 20; 203(3):731-41.
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    Score: 0.005
  145. Marrack P, Kappler J. The T cell and its receptor. Sci Am. 1986 Feb; 254(2):36-45.
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    Score: 0.005
  146. Kawahara DJ, Marrack P, Kappler JW. H-2-linked Ir gene control of VH determinant(s)-specific helper T cells. J Mol Cell Immunol. 1986; 2(5):255-64.
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    Score: 0.005
  147. Marrack P, Born W, Roehm N, Farr A, Kappler J. T cell receptors in the thymus. Biochem Soc Symp. 1986; 51:197-204.
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    Score: 0.005
  148. Farr AG, Anderson SK, Marrack P, Kappler J. Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ. Cell. 1985 Dec; 43(2 Pt 1):543-50.
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    Score: 0.005
  149. Roehm NW, Carbone A, Kushnir E, Taylor BA, Riblet RJ, Marrack P, Kappler JW. The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol. 1985 Sep; 135(3):2176-82.
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    Score: 0.004
  150. Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 2005 Jun; 52(6):1885-96.
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    Score: 0.004
  151. Czitrom AA, Edwards S, Phillips RA, Bosma MJ, Marrack P, Kappler JW. The function of antigen-presenting cells in mice with severe combined immunodeficiency. J Immunol. 1985 Apr; 134(4):2276-80.
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    Score: 0.004
  152. Grey HM, Chesnut RW, Shimonkevitz R, Marrack P, Kappler J. Mechanisms of antigen processing and presentation. Immunobiology. 1984 Dec; 168(3-5):202-12.
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    Score: 0.004
  153. Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P. Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7. J Exp Med. 2004 Nov 01; 200(9):1179-87.
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    Score: 0.004
  154. Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science. 2004 Jun 18; 304(5678):1808-10.
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    Score: 0.004
  155. Leibson HJ, Gefter M, Zlotnik A, Marrack P, Kappler JW. Role of gamma-interferon in antibody-producing responses. Nature. 1984 Jun 28-Jul 4; 309(5971):799-801.
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    Score: 0.004
  156. Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7681-6.
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    Score: 0.004
  157. Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 2004 Aug 01; 104(3):735-43.
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    Score: 0.004
  158. Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):1004-9.
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    Score: 0.004
  159. Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15035-40.
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    Score: 0.004
  160. Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med. 1983 Nov 01; 158(5):1635-46.
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    Score: 0.004
  161. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 1983 Nov; 35(1):295-302.
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    Score: 0.004
  162. Sunshine GH, Gold DP, Wortis HH, Marrack P, Kappler JW. Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas. J Exp Med. 1983 Nov 01; 158(5):1745-50.
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    Score: 0.004
  163. Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, Fitch F, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med. 1983 Oct 01; 158(4):1077-91.
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    Score: 0.004
  164. Endres RO, Marrack P, Kappler JW. An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region. J Immunol. 1983 Oct; 131(4):1656-62.
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    Score: 0.004
  165. Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell. 1983 Oct; 34(3):727-37.
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    Score: 0.004
  166. Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11565-70.
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    Score: 0.004
  167. Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nat Immunol. 2003 Oct; 4(10):974-81.
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    Score: 0.004
  168. Roehm NW, Marrack P, Kappler JW. Helper signals in the plaque-forming cell response to protein-bound haptens. J Exp Med. 1983 Aug 01; 158(2):317-33.
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    Score: 0.004
  169. Zlotnik A, Roberts WK, Vasil A, Blumenthal E, Larosa F, Leibson HJ, Endres RO, Graham SD, White J, Hill J, Henson P, Klein JR, Bevan MJ, Marrack P, Kappler JW. Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine? J Immunol. 1983 Aug; 131(2):794-800.
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    Score: 0.004
  170. Marrack P, Skidmore B, Kappler JW. Binding of antigen-specific, H-2-restricted T cell hybridomas to antigen-pulsed adherent cell monolayers. J Immunol. 1983 May; 130(5):2088-92.
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    Score: 0.004
  171. White J, Haskins KM, Marrack P, Kappler J. Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol. 1983 Mar; 130(3):1033-7.
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    Score: 0.004
  172. Marrack P, Kappler J. Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. J Exp Med. 1983 Feb 01; 157(2):404-18.
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    Score: 0.004
  173. Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev. 1983; 74:29-56.
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    Score: 0.004
  174. Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunol Rev. 1983; 76:131-45.
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    Score: 0.004
  175. Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Ann N Y Acad Sci. 2002 Dec; 975:114-31.
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    Score: 0.004
  176. Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 2002 Nov; 17(5):605-15.
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    Score: 0.004
  177. Liebson HJ, Marrack P, Kappler J. B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells. J Immunol. 1982 Oct; 129(4):1398-402.
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    Score: 0.004
  178. Freiberg BA, Kupfer H, Maslanik W, Delli J, Kappler J, Zaller DM, Kupfer A. Staging and resetting T cell activation in SMACs. Nat Immunol. 2002 Oct; 3(10):911-7.
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    Score: 0.004
  179. Jordan MB, van Rooijen N, Izui S, Kappler J, Marrack P. Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. Blood. 2003 Jan 15; 101(2):594-601.
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    Score: 0.004
  180. Roehm NW, Marrack P, Kappler JW. Antigen-specific, H-2-restricted helper T cell hybridomas. J Exp Med. 1982 Jul 01; 156(1):191-204.
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    Score: 0.004
  181. Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8832-7.
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    Score: 0.004
  182. Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 2002 Jun; 16(6):759-67.
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    Score: 0.004
  183. Myrick C, DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P, Wakeland EK. Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2. Genes Immun. 2002 May; 3(3):144-50.
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    Score: 0.004
  184. Marrack P, Graham SD, Kushnir E, Leibson HJ, Roehm N, Kappler JW. Nonspecific factors in B cell responses. Immunol Rev. 1982; 63:33-49.
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    Score: 0.003
  185. Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol. 2001 Dec 15; 214(2):110-22.
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    Score: 0.003
  186. Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nat Immunol. 2002 Jan; 3(1):27-32.
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    Score: 0.003
  187. Leibson HJ, Marrack P, Kappler JW. B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med. 1981 Nov 01; 154(5):1681-93.
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    Score: 0.003
  188. Schaefer BC, Mitchell TC, Kappler JW, Marrack P. A novel family of retroviral vectors for the rapid production of complex stable cell lines. Anal Biochem. 2001 Oct 01; 297(1):86-93.
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    Score: 0.003
  189. Kedl RM, Jordan M, Potter T, Kappler J, Marrack P, Dow S. CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10811-6.
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    Score: 0.003
  190. Kappler JW, Skidmore B, White J, Marrack P. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med. 1981 May 01; 153(5):1198-214.
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    Score: 0.003
  191. Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol. 2001 May; 2(5):397-402.
    View in: PubMed
    Score: 0.003
  192. Kersh GJ, Miley MJ, Nelson CA, Grakoui A, Horvath S, Donermeyer DL, Kappler J, Allen PM, Fremont DH. Structural and functional consequences of altering a peptide MHC anchor residue. J Immunol. 2001 Mar 01; 166(5):3345-54.
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    Score: 0.003
  193. Lang P, Stolpa JC, Freiberg BA, Crawford F, Kappler J, Kupfer A, Cambier JC. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science. 2001 Feb 23; 291(5508):1537-40.
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    Score: 0.003
  194. Ku CC, Kappler J, Marrack P. The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines. J Immunol. 2001 Feb 15; 166(4):2186-93.
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    Score: 0.003
  195. Fassò M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J Exp Med. 2000 Dec 18; 192(12):1719-30.
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    Score: 0.003
  196. Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays. J Exp Med. 1980 Nov 01; 152(5):1274-88.
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    Score: 0.003
  197. Kedl RM, Rees WA, Hildeman DA, Schaefer B, Mitchell T, Kappler J, Marrack P. T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med. 2000 Oct 16; 192(8):1105-13.
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    Score: 0.003
  198. Harwell L, Skidmore B, Marrack P, Kappler J. Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med. 1980 Oct 01; 152(4):893-904.
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    Score: 0.003
  199. Ku CC, Murakami M, Sakamoto A, Kappler J, Marrack P. Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science. 2000 Apr 28; 288(5466):675-8.
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    Score: 0.003
  200. Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. J Exp Med. 2000 Mar 20; 191(6):915-26.
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    Score: 0.003
  201. Keller DM, Swierkosz JE, Marrack P, Kappler JW. Two types of functionally distinct, synergizing helper T cells. J Immunol. 1980 Mar; 124(3):1350-9.
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    Score: 0.003
  202. Marrack P, Kappler JW. The two high responder haplotypes to (TG)-A--L do not cross-react in the helper T cell level. J Immunol. 1980 Feb; 124(2):1002-4.
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    Score: 0.003
  203. White J, Kappler J, Marrack P. Production and characterization of T cell hybridomas. Methods Mol Biol. 2000; 134:185-93.
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    Score: 0.003
  204. Swierkosz JE, Marrack P, Kappler JW. Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity. J Exp Med. 1979 Dec 01; 150(6):1293-309.
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    Score: 0.003
  205. Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12691-6.
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    Score: 0.003
  206. Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity. 1999 Oct; 11(4):411-21.
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    Score: 0.003
  207. Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med. 1999 Aug 02; 190(3):367-74.
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    Score: 0.003
  208. Swierkosz JE, Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. V. I-region control of helper T cell interaction with antigen-presenting macrophages. J Immunol. 1979 Aug; 123(2):654-9.
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    Score: 0.003
  209. Hildeman DA, Mitchell T, Teague TK, Henson P, Day BJ, Kappler J, Marrack PC. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity. 1999 Jun; 10(6):735-44.
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    Score: 0.003
  210. Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol. 1999 Apr 15; 162(8):4527-35.
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    Score: 0.003
  211. Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. J Exp Med. 1979 Mar 01; 149(3):780-5.
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    Score: 0.003
  212. Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. J Exp Med. 1999 Feb 01; 189(3):521-30.
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    Score: 0.003
  213. Kappler JW, Marrack P. The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med. 1978 Dec 01; 148(6):1510-22.
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    Score: 0.003
  214. Wilson NA, Wolf P, Ploegh H, Ignatowicz L, Kappler J, Marrack P. Invariant chain can bind MHC class II at a site other than the peptide binding groove. J Immunol. 1998 Nov 01; 161(9):4777-84.
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    Score: 0.003
  215. Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages. J Exp Med. 1978 Jun 01; 147(6):1596-610.
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    Score: 0.003
  216. Vella AT, Dow S, Potter TA, Kappler J, Marrack P. Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3810-5.
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    Score: 0.003
  217. Hoffmann MK, Kappler JW. Two distinct mechanisms of immune suppression by antibody. Nature. 1978 Mar 02; 272(5648):64-5.
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    Score: 0.003
  218. Swierkosz JE, Rock K, Marrack P, Kappler JW. The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 products. J Exp Med. 1978 Feb 01; 147(2):554-70.
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    Score: 0.003
  219. Ku CC, Kotzin B, Kappler J, Marrack P. CD8+ T-cell clones in old mice. Immunol Rev. 1997 Dec; 160:139-44.
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    Score: 0.003
  220. Liu CP, Parker D, Kappler J, Marrack P. Selection of antigen-specific T cells by a single IEk peptide combination. J Exp Med. 1997 Nov 03; 186(9):1441-50.
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    Score: 0.003
  221. Araneo BA, Marrack P, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. VII. Conversion of T1 cells to T2 cells by antigen. J Immunol. 1977 Aug; 119(2):765-71.
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    Score: 0.003
  222. Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
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    Score: 0.003
  223. Vella A, Teague TK, Ihle J, Kappler J, Marrack P. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med. 1997 Jul 21; 186(2):325-30.
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    Score: 0.003
  224. Teague TK, Marrack P, Kappler JW, Vella AT. IL-6 rescues resting mouse T cells from apoptosis. J Immunol. 1997 Jun 15; 158(12):5791-6.
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    Score: 0.003
  225. Vella AT, Mitchell T, Groth B, Linsley PS, Green JM, Thompson CB, Kappler JW, Marrack P. CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo. J Immunol. 1997 May 15; 158(10):4714-20.
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    Score: 0.003
  226. Ku CC, Kappler J, Marrack P. Characteristics and maintenance of CD8+ T-cell clones found in old mice. Mech Ageing Dev. 1997 Mar; 94(1-3):41-53.
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    Score: 0.002
  227. Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1350-5.
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    Score: 0.002
  228. Liu CP, Lin WJ, Huang M, Kappler JW, Marrack P. Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):616-21.
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    Score: 0.002
  229. Harwell L, Marrack P, Kappler JW. Suppressor T-cell inactivation of a helper T-cell factor. Nature. 1977 Jan 06; 265(5589):57-9.
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    Score: 0.002
  230. Horan PK, Kappler JW. Automated fluorescent analysis for cytotoxicity assays. J Immunol Methods. 1977; 18(3-4):309-16.
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    Score: 0.002
  231. Araneo BA, Marrack PC, Kappler JW. Functional heterongeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation. J Immunol. 1976 Dec; 117(6):2131-6.
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    Score: 0.002
  232. Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med. 1996 Nov 01; 184(5):1619-30.
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    Score: 0.002
  233. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. IV. Development of a model system demonstrating responsiveness of two T cell functions to HGG in vitro. J Immunol. 1976 Nov; 117(5 Pt.2):1953-9.
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    Score: 0.002
  234. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. V. Unresponsiveness to HGG in vitro of these two T cell subpopulations. J Immunol. 1976 Nov; 117(5 Pt.2):1960-5.
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    Score: 0.002
  235. Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. V. Response kinetics of peripheral T cell subpopulations. J Immunol. 1976 Oct; 117(4):1233-7.
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    Score: 0.002
  236. Ignatowicz L, Kappler J, Parker DC, Marrack P. The responses of mature T cells are not necessarily antagonized by their positively selecting peptide. J Immunol. 1996 Sep 01; 157(5):1827-31.
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    Score: 0.002
  237. Kappler JW, Marrack PC. Helper T cells recognise antigen and macrophage surface components simultaneously. Nature. 1976 Aug 26; 262(5571):797-9.
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    Score: 0.002
  238. Marrack P, Kappler JW. Antigen-specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T cells distinguished by their antigen sensitivities. J Immunol. 1976 May; 116(5):1373-8.
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    Score: 0.002
  239. Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 1996 Feb 23; 84(4):521-9.
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    Score: 0.002
  240. Vella AT, Scherer MT, Schultz L, Kappler JW, Marrack P. B cells are not essential for peripheral T-cell tolerance. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):951-5.
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    Score: 0.002
  241. Scherer MT, Ignatowicz L, Pullen A, Kappler J, Marrack P. The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med. 1995 Nov 01; 182(5):1493-504.
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    Score: 0.002
  242. Kappler JW, Marrack PC. Functional heterogeneity among the T-derived lymphocytes of the mouse. III. Helper and suppressor T-cells activated by concanavalin A. Cell Immunol. 1975 Jul; 18(1):9-20.
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    Score: 0.002
  243. Ignatowicz L, Winslow G, Bill J, Kappler J, Marrack P. Cell surface expression of class II MHC proteins bound by a single peptide. J Immunol. 1995 Apr 15; 154(8):3852-62.
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    Score: 0.002
  244. Marrack PC, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells. J Immunol. 1975 Mar; 114(3):1116-25.
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    Score: 0.002
  245. Vella AT, McCormack JE, Linsley PS, Kappler JW, Marrack P. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity. 1995 Mar; 2(3):261-70.
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    Score: 0.002
  246. Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. II. Sensitivity of subpopulations to anti-thymocyte serum. J Immunol. 1975 Feb; 114(2 pt 2):747-51.
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    Score: 0.002
  247. McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2086-90.
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    Score: 0.002
  248. Kappler JW. A micro-technique for hemolytic plaque assays. J Immunol. 1974 Mar; 112(3):1271-4.
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    Score: 0.002
  249. Hugo P, Kappler JW, Godfrey DI, Marrack PC. Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion. J Immunol. 1994 Feb 01; 152(3):1022-31.
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    Score: 0.002
  250. Ignatowicz L, Kappler JW, Marrack P, Scherer MT. Identification of two V beta 7-specific viral superantigens. J Immunol. 1994 Jan 01; 152(1):65-71.
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    Score: 0.002
  251. Callahan JE, Kappler JW, Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J Immunol. 1993 Dec 15; 151(12):6657-69.
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    Score: 0.002
  252. Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II. J Exp Med. 1993 Dec 01; 178(6):2173-83.
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    Score: 0.002
  253. Hugo P, Kappler JW, McCormack JE, Marrack P. Fibroblasts can induce thymocyte positive selection in vivo. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10335-9.
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    Score: 0.002
  254. Kappler JW, van der Hoven A, Dharmarajan U, Hoffmann M. Regulation of the immune response. IV. Antibody-mediated suppression of the immune response to haptens and heterologous erythrocyte antigens in vitro. J Immunol. 1973 Oct; 111(4):1228-35.
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    Score: 0.002
  255. Hugo P, Kappler JW, Marrack PC. Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? Immunol Rev. 1993 Oct; 135:133-55.
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    Score: 0.002
  256. Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ. Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun. 1993 Aug; 61(8):3175-83.
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    Score: 0.002
  257. Kappler JW, Hoffmann M. Regulation of the immune response. 3. Kinetic differences between thymus- and bone marrow- derived lymphocytes in the proliferative response to heterologous erythrocytes. J Exp Med. 1973 Jun 01; 137(6):1325-37.
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    Score: 0.002
  258. McCormack JE, Callahan JE, Kappler J, Marrack PC. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J Immunol. 1993 May 01; 150(9):3785-92.
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    Score: 0.002
  259. Hoffmann M, Kappler JW. Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen. J Exp Med. 1973 Mar 01; 137(3):721-39.
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    Score: 0.002
  260. Scherer MT, Ignatowicz L, Winslow GM, Kappler JW, Marrack P. Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol. 1993; 9:101-28.
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    Score: 0.002
  261. Hugo P, Kappler JW, Godfrey DI, Marrack PC. A cell line that can induce thymocyte positive selection. Nature. 1992 Dec 17; 360(6405):679-82.
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    Score: 0.002
  262. Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 1992 Nov 27; 71(5):719-30.
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    Score: 0.002
  263. Finkel TH, Kappler JW, Marrack PC. Immature thymocytes are protected from deletion early in ontogeny. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3372-4.
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    Score: 0.002
  264. Ignatowicz L, Kappler J, Marrack P. The effects of chronic infection with a superantigen-producing virus. J Exp Med. 1992 Apr 01; 175(4):917-23.
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    Score: 0.002
  265. Pullen AM, Choi Y, Kushnir E, Kappler J, Marrack P. The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med. 1992 Jan 01; 175(1):41-7.
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    Score: 0.002
  266. Hoffmann M, Kappler JW. The antigen specificity of thymus-derived helper cells. J Immunol. 1972 Jan; 108(1):261-3.
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    Score: 0.002
  267. McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cell Immunol. 1991 Dec; 138(2):413-22.
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    Score: 0.002
  268. Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8357-61.
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    Score: 0.002
  269. Kappler JW, Hoffmann M, Dutton RW. Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med. 1971 Sep 01; 134(3 Pt 1):577-87.
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    Score: 0.002
  270. Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P. Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6682-6.
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    Score: 0.002
  271. Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 1991 Mar 21; 350(6315):203-7.
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    Score: 0.002
  272. Blackman MA, Kappler JW, Marrack P. Multiple mechanisms of T cell tolerance to Mls-1a. Adv Exp Med Biol. 1991; 292:159-65.
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    Score: 0.002
  273. McCormack JE, Kappler J, Marrack P, Westcott JY. Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture. J Immunol. 1991 Jan 01; 146(1):239-43.
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    Score: 0.002
  274. Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 1990 Sep 21; 62(6):1115-21.
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    Score: 0.002
  275. Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med. 1990 Sep 01; 172(3):709-17.
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    Score: 0.002
  276. Blackman M, Kappler J, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells. Science. 1990 Jun 15; 248(4961):1335-41.
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    Score: 0.002
  277. Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science. 1990 Jun 08; 248(4960):1227-30.
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    Score: 0.002
  278. Blackman MA, Burgert HG, Gerhard-Burgert H, Woodland DL, Palmer E, Kappler JW, Marrack P. A role for clonal inactivation in T cell tolerance to Mls-1a. Nature. 1990 Jun 07; 345(6275):540-2.
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    Score: 0.002
  279. Callahan JE, Herman A, Kappler JW, Marrack P. Stimulation of B10.BR T cells with superantigenic staphylococcal toxins. J Immunol. 1990 Apr 01; 144(7):2473-9.
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    Score: 0.002
  280. Kappler JW. The kinetics of DNA methylation in cultures of a mouse adrenal cell line. J Cell Physiol. 1970 Feb; 75(1):21-31.
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    Score: 0.002
  281. Golde WT, McDuffie M, Kappler J, Marrack P. Identification of a new cell surface glycoprotein with accessory function in murine T cell responses. J Immunol. 1990 Feb 01; 144(3):804-10.
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    Score: 0.002
  282. White J, Blackman M, Bill J, Kappler J, Marrack P, Gold DP, Born W. Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol. 1989 Sep 15; 143(6):1822-5.
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    Score: 0.001
  283. Kotzin BL, Kappler JW, Marrack PC, Herron LR. T cell tolerance to self antigens in New Zealand hybrid mice with lupus-like disease. J Immunol. 1989 Jul 01; 143(1):89-94.
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    Score: 0.001
  284. Finkel TH, Marrack P, Kappler JW, Kubo RT, Cambier JC. Alpha beta T cell receptor and CD3 transduce different signals in immature T cells. Implications for selection and tolerance. J Immunol. 1989 May 01; 142(9):3006-12.
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    Score: 0.001
  285. Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol. 1989 Apr 15; 142(8):2736-42.
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    Score: 0.001
  286. Pullen AM, Kappler JW, Marrack P. Tolerance to self antigens shapes the T-cell repertoire. Immunol Rev. 1989 Feb; 107:125-39.
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    Score: 0.001
  287. White J, Herman A, Pullen AM, Kubo R, Kappler JW, Marrack P. The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell. 1989 Jan 13; 56(1):27-35.
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    Score: 0.001
  288. Yague J, Blackman M, Born W, Marrack P, Kappler J, Palmer E. The structure of V alpha and J alpha segments in the mouse. Nucleic Acids Res. 1988 Dec 09; 16(23):11355-64.
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    Score: 0.001
  289. McDuffie M, Roehm N, Kappler JW, Marrack P. Involvement of major histocompatibility complex products in tolerance induction in the thymus. J Immunol. 1988 Sep 15; 141(6):1840-7.
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    Score: 0.001
  290. Fenton RG, Marrack P, Kappler JW, Kanagawa O, Seidman JG. Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene. Science. 1988 Aug 26; 241(4869):1089-92.
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    Score: 0.001
  291. van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 1988 May 06; 53(3):357-70.
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    Score: 0.001
  292. Born W, White J, Kappler J, Marrack P. Rearrangement of IgH genes in normal thymocyte development. J Immunol. 1988 May 01; 140(9):3228-32.
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    Score: 0.001
  293. Blackman MA, Kappler JW, Marrack P. T-cell specificity and repertoire. Immunol Rev. 1988 Jan; 101:5-19.
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    Score: 0.001
  294. Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking. Nature. 1987 Nov 12-18; 330(6144):179-81.
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    Score: 0.001
  295. Born W, McDuffie M, Roehm N, Kushnir E, White J, Thorpe D, Stefano J, Kappler J, Marrack P. Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J Immunol. 1987 Feb 15; 138(4):999-1008.
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    Score: 0.001
  296. Gay D, Kappler J, Marrack P. L3T4 interacts with class II molecules on target cells. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):127-31.
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    Score: 0.001
  297. Golde WT, Gay D, Kappler J, Marrack P. The role of LFA-1 in class II restricted, antigen-specific T-cell responses. Cell Immunol. 1986 Nov; 103(1):73-83.
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    Score: 0.001
  298. Gay D, Coeshott C, Golde W, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. IX. Role of accessory molecules in recognition of antigen plus isolated IA. J Immunol. 1986 Mar 15; 136(6):2026-32.
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    Score: 0.001
  299. Yagüe J, White J, Coleclough C, Kappler J, Palmer E, Marrack P. The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell. 1985 Aug; 42(1):81-7.
    View in: PubMed
    Score: 0.001
  300. Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M. Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 01; 161(5):1219-24.
    View in: PubMed
    Score: 0.001
  301. Born W, Yagüe J, Palmer E, Kappler J, Marrack P. Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A. 1985 May; 82(9):2925-9.
    View in: PubMed
    Score: 0.001
  302. Golde WT, Kappler JW, Greenstein J, Malissen B, Hood L, Marrack P. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. J Exp Med. 1985 Mar 01; 161(3):635-40.
    View in: PubMed
    Score: 0.001
  303. Watts TH, Brian AA, Kappler JW, Marrack P, McConnell HM. Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7564-8.
    View in: PubMed
    Score: 0.001
  304. Shimonkevitz R, Colon S, Kappler JW, Marrack P, Grey HM. Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol. 1984 Oct; 133(4):2067-74.
    View in: PubMed
    Score: 0.001
  305. Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunol Rev. 1984 Oct; 81:161-76.
    View in: PubMed
    Score: 0.001
  306. Roehm N, Herron L, Cambier J, DiGuisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell. 1984 Sep; 38(2):577-84.
    View in: PubMed
    Score: 0.001
  307. Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, Cambier JC. Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med. 1984 Sep 01; 160(3):679-94.
    View in: PubMed
    Score: 0.001
  308. Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med. 1984 Aug 01; 160(2):452-71.
    View in: PubMed
    Score: 0.001
  309. Greenstein JL, Kappler J, Marrack P, Burakoff SJ. The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med. 1984 Apr 01; 159(4):1213-24.
    View in: PubMed
    Score: 0.001
  310. Folsom V, Gold DP, White J, Marrack P, Kappler J, Tonegawa S. Functional and inducible expression of a transfected murine class II major histocompatibility complex gene. Proc Natl Acad Sci U S A. 1984 Apr; 81(7):2045-9.
    View in: PubMed
    Score: 0.001
  311. Malissen B, Price MP, Goverman JM, McMillan M, White J, Kappler J, Marrack P, Pierres A, Pierres M, Hood L. Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell. 1984 Feb; 36(2):319-27.
    View in: PubMed
    Score: 0.001
  312. Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. Annu Rev Immunol. 1984; 2:51-66.
    View in: PubMed
    Score: 0.001
  313. Zlotnik A, Shimonkevitz RP, Gefter ML, Kappler J, Marrack P. Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. J Immunol. 1983 Dec; 131(6):2814-20.
    View in: PubMed
    Score: 0.001
  314. Wilde DB, Marrack P, Kappler J, Dialynas DP, Fitch FW. Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J Immunol. 1983 Nov; 131(5):2178-83.
    View in: PubMed
    Score: 0.001
  315. Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
    View in: PubMed
    Score: 0.001
  316. Shimonkevitz R, Kappler J, Marrack P, Grey H. Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med. 1983 Aug 01; 158(2):303-16.
    View in: PubMed
    Score: 0.001
  317. Daughety TW, Marrack P, Kappler JW, Chiller JM. The capacity of murine alveolar macrophages to stimulate antigen-dependent T-lymphocyte activation and proliferation. Cell Immunol. 1983 Jul 15; 79(2):374-82.
    View in: PubMed
    Score: 0.001
  318. Kronenberg M, Kraig E, Siu G, Kapp JA, Kappler J, Marrack P, Pierce CW, Hood L. Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts. J Exp Med. 1983 Jul 01; 158(1):210-27.
    View in: PubMed
    Score: 0.001
  319. Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med. 1983 Apr 01; 157(4):1149-69.
    View in: PubMed
    Score: 0.001
  320. Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens. J Immunol. 1983 Feb; 130(2):781-4.
    View in: PubMed
    Score: 0.001
  321. Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med. 1983 Feb 01; 157(2):600-12.
    View in: PubMed
    Score: 0.001
  322. Walker E, Warner NL, Chesnut R, Kappler J, Marrack P. Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol. 1982 May; 128(5):2164-9.
    View in: PubMed
    Score: 0.001
  323. Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A role for T cell helper factors in antibody responses to "T-independent" antigens. Lymphokine Res. 1982; 1(4):99-106.
    View in: PubMed
    Score: 0.001
  324. Greenstein JL, Lord E, Kappler JW, Marrack PC. Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help. J Exp Med. 1981 Nov 01; 154(5):1608-17.
    View in: PubMed
    Score: 0.001
  325. Greenstein JL, Lord EM, Horan P, Kappler JW, Marrack P. Functional subsets of B cells defined by quantitative differences in surface I-A. J Immunol. 1981 Jun; 126(6):2419-23.
    View in: PubMed
    Score: 0.001
  326. Greenstein JL, Leary J, Horan P, Kappler JW, Marrack P. Flow sorting of antigen-binding B cell subsets. J Immunol. 1980 Mar; 124(3):1472-81.
    View in: PubMed
    Score: 0.001
  327. Berkarda B, Marrack P, Kappler JW, Bakemeier RF. Effects of warfarin administration on the immune response of mice. Arzneimittelforschung. 1978; 28(8):1407-10.
    View in: PubMed
    Score: 0.001
  328. Harwell L, Kappler JW, Marrack P. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources. J Immunol. 1976 May; 116(5):1379-84.
    View in: PubMed
    Score: 0.001
  329. Burns FD, Marrack PC, Kappler JW, Janeway CA. Functional heterogeneity among the T-derived lymphocytes of the mouse. IV. Nature of spontaneously induced suppressor cells. J Immunol. 1975 Apr; 114(4):1345-7.
    View in: PubMed
    Score: 0.001
  330. Hunter PM, Kappler JW, Kettman JR. The frequency and activity of single helper T cells. J Immunol. 1974 Sep; 113(3):830-4.
    View in: PubMed
    Score: 0.001
  331. Hoffmann MK, Kappler JW, Hirst JA, Oettgen HF. Regulation of the immune response. V. Antibody-mediated inhibition of T and B cell cooperation in the in vitro response to red cell antigens. Eur J Immunol. 1974 Apr; 4(4):282-6.
    View in: PubMed
    Score: 0.001
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