 Connection
John Kappler to Animals
This is a "connection" page, showing publications John Kappler has written about Animals.
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1.578 |
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Reed BK, Kappler JW. Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes. Front Immunol. 2021; 12:669986.
Score: 0.037
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Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).
Score: 0.037
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Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor. Elife. 2017 11 17; 6.
Score: 0.029
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Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):E5608-17.
Score: 0.027
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Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23.
Score: 0.025
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Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. PLoS One. 2015; 10(8):e0136613.
Score: 0.025
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Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR a genes in an Ikaros null thymoma cell line. Eur J Immunol. 2013 Feb; 43(2):521-32.
Score: 0.021
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Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
Score: 0.019
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Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 2011 Jul 22; 35(1):23-33.
Score: 0.019
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Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10978-83.
Score: 0.018
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Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol. 2009 Dec; 7(12):e1000253.
Score: 0.017
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Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7951-6.
Score: 0.016
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Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Curr Opin Immunol. 2008 Apr; 20(2):203-7.
Score: 0.015
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Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 2008 Mar; 28(3):324-34.
Score: 0.015
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Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203.
Score: 0.015
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Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat Immunol. 2006 Nov; 7(11):1191-9.
Score: 0.014
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Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol Rev. 2006 Apr; 210:156-70.
Score: 0.013
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Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol. 2006 Mar 01; 176(5):2683-90.
Score: 0.013
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Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 2005 Jul 29; 122(2):247-60.
Score: 0.013
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Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2476-81.
Score: 0.012
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Brown AJ, White J, Shaw L, Gross J, Slabodkin A, Kushner E, Greiff V, Matsuda J, Gapin L, Scott-Browne J, Kappler J, Marrack P. MHC heterozygosity limits T cell receptor variability in CD4 T cells. Sci Immunol. 2024 07 12; 9(97):eado5295.
Score: 0.012
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Smith JA, Yuen BTK, Purtha W, Balolong JM, Phipps JD, Crawford F, Bluestone JA, Kappler JW, Anderson MS. Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Proc Natl Acad Sci U S A. 2024 May 14; 121(20):e2320268121.
Score: 0.012
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Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. PLoS Biol. 2004 Apr; 2(4):E90.
Score: 0.011
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Marrack P, Kappler J. Control of T cell viability. Annu Rev Immunol. 2004; 22:765-87.
Score: 0.011
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Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep; 19(3):341-52.
Score: 0.011
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Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. J Exp Med. 2003 Mar 03; 197(5):567-74.
Score: 0.011
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Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). J Exp Med. 2002 Apr 15; 195(8):1043-52.
Score: 0.010
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Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes. 2021 11; 70(11):2580-2594.
Score: 0.010
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Ramos SA, Morton JJ, Yadav P, Reed B, Alizadeh SI, Shilleh AH, Perrenoud L, Jaggers J, Kappler J, Jimeno A, Russ HA. Generation of functional human thymic cells from induced pluripotent stem cells. J Allergy Clin Immunol. 2022 02; 149(2):767-781.e6.
Score: 0.009
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Marrack P, Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? J Immunol. 2001 Jul 15; 167(2):617-21.
Score: 0.009
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Wei P, Jordan KR, Buhrman JD, Lei J, Deng H, Marrack P, Dai S, Kappler JW, Slansky JE, Yin L. Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
Score: 0.009
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Falta MT, Crawford JC, Tinega AN, Landry LG, Crawford F, Mack DG, Martin AK, Atif SM, Li L, Santos RG, Nakayama M, Kappler JW, Maier LA, Thomas PG, Pinilla C, Fontenot AP. Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation. J Clin Invest. 2021 05 03; 131(9).
Score: 0.009
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Wilson N, Fremont D, Marrack P, Kappler J. Mutations changing the kinetics of class II MHC peptide exchange. Immunity. 2001 May; 14(5):513-22.
Score: 0.009
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Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
Score: 0.009
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Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nat Immunol. 2000 Aug; 1(2):107-11.
Score: 0.009
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Kappler J, Franken S, Junghans U, Hoffmann R, Linke T, Müller HW, Koch KW. Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1. Biochem Biophys Res Commun. 2000 May 10; 271(2):287-91.
Score: 0.009
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Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Curr Opin Immunol. 2000 Apr; 12(2):206-9.
Score: 0.009
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Lee S, Liu H, Hill R, Chen C, Hong X, Crawford F, Kingsley M, Zhang Q, Liu X, Chen Z, Lengeling A, Bernt KM, Marrack P, Kappler J, Zhou Q, Li CY, Xue Y, Hansen K, Zhang G. JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife. 2020 02 12; 9.
Score: 0.009
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Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):291-6.
Score: 0.009
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Cepeda JR, Sekhar NS, Han J, Xiong W, Zhang N, Yu L, Dai S, Davidson HW, Kappler JW, An Z, Zhang L. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. MAbs. 2020 Jan-Dec; 12(1):1836714.
Score: 0.009
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Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22252-22261.
Score: 0.008
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Clayton GM, White J, Lee S, Kappler JW, Chan SK. Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6. PLoS One. 2019; 14(9):e0213052.
Score: 0.008
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Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9781-6.
Score: 0.008
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Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
Score: 0.008
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White J, Crawford F, Fremont D, Marrack P, Kappler J. Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. J Immunol. 1999 Mar 01; 162(5):2671-6.
Score: 0.008
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Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunol Rev. 1998 Oct; 165:279-85.
Score: 0.008
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Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 1998 Sep; 9(3):385-93.
Score: 0.008
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Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 1998 Jun; 8(6):675-82.
Score: 0.008
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Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep. 2018 02 19; 8(1):3275.
Score: 0.007
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Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167.
Score: 0.007
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Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7717-E7726.
Score: 0.007
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Seibel JL, Wilson N, Kozono H, Marrack P, Kappler JW. Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition. J Exp Med. 1997 Jun 02; 185(11):1919-27.
Score: 0.007
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Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P. The domestic cat antibody response to feline herpesvirus-1 increases with age. Vet Immunol Immunopathol. 2017 Jun; 188:65-70.
Score: 0.007
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Hamad AR, Marrack P, Kappler JW. Transcytosis of staphylococcal superantigen toxins. J Exp Med. 1997 Apr 21; 185(8):1447-54.
Score: 0.007
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Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol. 1997 Apr; 9(2):250-5.
Score: 0.007
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Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
Score: 0.007
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Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFN? in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. PLoS One. 2016; 11(11):e0166322.
Score: 0.007
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Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine aß T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. J Immunol. 2016 11 01; 197(9):3437-3443.
Score: 0.007
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Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. J Immunol. 2016 08 15; 197(4):1221-30.
Score: 0.007
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Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 1996 May 17; 272(5264):1001-4.
Score: 0.007
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Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 1995 Aug; 3(2):187-96.
Score: 0.006
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Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunol. 2016 Jan; 9(1):218-28.
Score: 0.006
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Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. J Immunol. 2015 Jul 01; 195(1):71-9.
Score: 0.006
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Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4429-34.
Score: 0.006
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Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science. 2014 Oct 17; 346(6207):363-8.
Score: 0.006
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Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14840-5.
Score: 0.006
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Kappler J, White J, Kozono H, Clements J, Marrack P. Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8462-6.
Score: 0.006
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Hamad AR, Herman A, Marrack P, Kappler JW. Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B. J Exp Med. 1994 Aug 01; 180(2):615-21.
Score: 0.006
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Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8553-8.
Score: 0.006
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Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994 May 12; 369(6476):151-4.
Score: 0.006
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David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
Score: 0.006
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Winslow GM, Marrack P, Kappler JW. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1994 Apr; 1(1):23-33.
Score: 0.006
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Zhang L, Crawford F, Yu L, Michels A, Nakayama M, Davidson HW, Kappler JW, Eisenbarth GS. Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2656-61.
Score: 0.006
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Marrack P, Kappler J. Subversion of the immune system by pathogens. Cell. 1994 Jan 28; 76(2):323-32.
Score: 0.006
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Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E119-28.
Score: 0.006
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Buhrman JD, Jordan KR, Munson DJ, Moore BL, Kappler JW, Slansky JE. Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor. J Biol Chem. 2013 Nov 15; 288(46):33213-25.
Score: 0.006
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Marrack P, Kappler JW. How the immune system recognizes the body. Sci Am. 1993 Sep; 269(3):80-3, 86-9.
Score: 0.005
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Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3216-24.
Score: 0.005
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Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. J Exp Med. 2013 Jul 01; 210(7):1403-18.
Score: 0.005
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Marrack P, Hugo P, McCormack J, Kappler J. Death and T cells. Immunol Rev. 1993 Jun; 133:119-29.
Score: 0.005
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Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. PLoS One. 2013; 8(4):e61775.
Score: 0.005
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Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunol Res. 2013 Mar; 55(1-3):210-6.
Score: 0.005
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McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1122-31.
Score: 0.005
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Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. PLoS One. 2013; 8(2):e57435.
Score: 0.005
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Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions. Immunol Rev. 1993 Feb; 131:79-92.
Score: 0.005
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Marrack P, McCormack J, Callahan J, Ignatowicz L, Kappler J. T cell tolerance. Giles F. Filley Lecture. Chest. 1993 Feb; 103(2 Suppl):76S-78S.
Score: 0.005
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Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. PLoS One. 2013; 8(1):e53789.
Score: 0.005
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Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein Cell. 2013 Jan; 4(1):8-16.
Score: 0.005
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White J, Pullen A, Choi K, Marrack P, Kappler JW. Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor. J Exp Med. 1993 Jan 01; 177(1):119-25.
Score: 0.005
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Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60.
Score: 0.005
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Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol. 2012 Jul 19; 13(8):705-6.
Score: 0.005
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Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 2012 Jun 29; 36(6):887-8.
Score: 0.005
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Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. J Exp Med. 1992 Mar 01; 175(3):847-52.
Score: 0.005
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Jordan KR, Buhrman JD, Sprague J, Moore BL, Gao D, Kappler JW, Slansky JE. TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines. Cancer Immunol Immunother. 2012 Oct; 61(10):1627-38.
Score: 0.005
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Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med. 1992 Feb 01; 175(2):387-96.
Score: 0.005
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Zhang L, Stadinski BD, Michels A, Kappler JW, Eisenbarth GS. Immunization with an insulin peptide-MHC complex to prevent type 1 diabetes of NOD mice. Diabetes Metab Res Rev. 2011 Nov; 27(8):784-9.
Score: 0.005
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Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to aß T cell receptor specificity. Immunity. 2011 Oct 28; 35(4):526-35.
Score: 0.005
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Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. J Immunol. 2011 Oct 01; 187(7):3694-703.
Score: 0.005
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Kenyon KD, Cole C, Crawford F, Kappler JW, Thurman JM, Bratton DL, Boackle SA, Henson PM. IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity. J Immunol. 2011 Sep 01; 187(5):2101-11.
Score: 0.005
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Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c? B-cell population is important for the development of autoimmunity. Blood. 2011 Aug 04; 118(5):1305-15.
Score: 0.005
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Pullen AM, Bill J, Kubo RT, Marrack P, Kappler JW. Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta. J Exp Med. 1991 May 01; 173(5):1183-92.
Score: 0.005
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MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7914-9.
Score: 0.005
-
Marrack P, Kushnir E, Kappler J. A maternally inherited superantigen encoded by a mammary tumour virus. Nature. 1991 Feb 07; 349(6309):524-6.
Score: 0.005
-
MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
Score: 0.005
-
Munks MW, McKee AS, Macleod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P. Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo. Blood. 2010 Dec 09; 116(24):5191-9.
Score: 0.004
-
Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 1990 Aug 02; 346(6283):471-3.
Score: 0.004
-
Pullen AM, Wade T, Marrack P, Kappler JW. Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell. 1990 Jun 29; 61(7):1365-74.
Score: 0.004
-
Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 May 11; 248(4956):705-11.
Score: 0.004
-
Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. J Immunol. 2010 May 01; 184(9):4592-5.
Score: 0.004
-
Stadinski B, Kappler J, Eisenbarth GS. Molecular targeting of islet autoantigens. Immunity. 2010 Apr 23; 32(4):446-56.
Score: 0.004
-
Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30.
Score: 0.004
-
MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 2010 May; 130(1):10-5.
Score: 0.004
-
Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31.
Score: 0.004
-
Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmun Rev. 2010 May; 9(7):494-8.
Score: 0.004
-
Marrack P, Blackman M, Kushnir E, Kappler J. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med. 1990 Feb 01; 171(2):455-64.
Score: 0.004
-
Jordan KR, McMahan RH, Kemmler CB, Kappler JW, Slansky JE. Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4652-7.
Score: 0.004
-
Marrack P, Kappler J. T cell tolerance. Semin Immunol. 1990 Jan; 2(1):45-9.
Score: 0.004
-
Marrack P, Kappler JW. The T cell receptors. Chem Immunol. 1990; 49:69-81.
Score: 0.004
-
Burgert HG, White J, Weltzien HU, Marrack P, Kappler JW. Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner. J Exp Med. 1989 Dec 01; 170(6):1887-904.
Score: 0.004
-
Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8941-5.
Score: 0.004
-
Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 1989 Sep 22; 58(6):1047-54.
Score: 0.004
-
McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol. 2009 Oct 01; 183(7):4403-14.
Score: 0.004
-
Pullen AM, Marrack P, Kappler JW. Evidence that Mls-2 antigens which delete V beta 3+ T cells are controlled by multiple genes. J Immunol. 1989 May 01; 142(9):3033-7.
Score: 0.004
-
Kappler JW, Kushnir E, Marrack P. Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype. J Exp Med. 1989 May 01; 169(5):1533-41.
Score: 0.004
-
Blackman MA, Marrack P, Kappler J. Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science. 1989 Apr 14; 244(4901):214-7.
Score: 0.004
-
Marrack P, McCormack J, Kappler J. Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium. Nature. 1989 Apr 06; 338(6215):503-5.
Score: 0.004
-
Jordan KR, Crawford F, Kappler JW, Slansky JE. Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins. Curr Protoc Immunol. 2009 Apr; Chapter 2:2.15.1-2.15.23.
Score: 0.004
-
Desbien AL, Kappler JW, Marrack P. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5663-8.
Score: 0.004
-
MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Semin Immunol. 2009 Apr; 21(2):53-61.
Score: 0.004
-
Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 2009 Apr 23; 458(7241):1043-6.
Score: 0.004
-
Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. Int Immunol. 2009 Apr; 21(4):339-48.
Score: 0.004
-
Kappler JW, Pullen A, Callahan J, Choi Y, Herman A, White J, Potts W, Wakeland E, Marrack P. Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:401-7.
Score: 0.004
-
Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:105-10.
Score: 0.004
-
Carbone AM, Marrack P, Kappler JW. Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors. Science. 1988 Nov 25; 242(4882):1174-6.
Score: 0.004
-
O'Brien RL, Marrack P, Storb U, Kappler JW. B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells. J Immunol. 1988 Nov 15; 141(10):3335-41.
Score: 0.004
-
Pullen AM, Marrack P, Kappler JW. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature. 1988 Oct 27; 335(6193):796-801.
Score: 0.004
-
Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nat Immunol. 2008 Dec; 9(12):1356-63.
Score: 0.004
-
Marrack P, Kappler J. The T-cell repertoire for antigen and MHC. Immunol Today. 1988 Oct; 9(10):308-15.
Score: 0.004
-
Wade T, Bill J, Marrack PC, Palmer E, Kappler JW. Molecular basis for the nonexpression of V beta 17 in some strains of mice. J Immunol. 1988 Sep 15; 141(6):2165-7.
Score: 0.004
-
MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14521-6.
Score: 0.004
-
Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12997-3002.
Score: 0.004
-
Carbone AM, Marrack P, Kappler JW. Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression. J Immunol. 1988 Aug 15; 141(4):1369-75.
Score: 0.004
-
Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 1988 May 20; 53(4):627-34.
Score: 0.004
-
Marrack P, Kappler J. T cells can distinguish between allogeneic major histocompatibility complex products on different cell types. Nature. 1988 Apr 28; 332(6167):840-3.
Score: 0.004
-
Marrack P, Kushnir E, Born W, McDuffie M, Kappler J. The development of helper T cell precursors in mouse thymus. J Immunol. 1988 Apr 15; 140(8):2508-14.
Score: 0.004
-
McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol. 2008 May; 20(5):659-69.
Score: 0.004
-
Kappler JW, Staerz U, White J, Marrack PC. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature. 1988 Mar 03; 332(6159):35-40.
Score: 0.004
-
Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008 Feb; 45(3):599-606.
Score: 0.004
-
Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE. Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity. J Immunol. 2008 Jan 01; 180(1):188-97.
Score: 0.004
-
McDuffie M, Roehm N, Born W, Marrack P, Kappler JW. T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire. Transplant Proc. 1987 Dec; 19(6 Suppl 7):111-6.
Score: 0.004
-
Marrack P, Kappler J. The T cell receptor. Science. 1987 Nov 20; 238(4830):1073-9.
Score: 0.004
-
Hannum C, Marrack P, Kubo R, Kappler J. Thymocytes with the predicted properties of pre-T cells. J Exp Med. 1987 Oct 01; 166(4):874-89.
Score: 0.004
-
Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. J Immunol. 2007 Sep 15; 179(6):3417-24.
Score: 0.004
-
Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol. 2007 Oct; 8(10):1105-13.
Score: 0.004
-
Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J, et al. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 1987 Aug 13-19; 328(6131):626-9.
Score: 0.004
-
Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Curr Opin Immunol. 2007 Oct; 19(5):516-21.
Score: 0.004
-
Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest. 2007 May; 117(5):1270-81.
Score: 0.004
-
Kappler JW, Wade T, White J, Kushnir E, Blackman M, Bill J, Roehm N, Marrack P. A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell. 1987 Apr 24; 49(2):263-71.
Score: 0.004
-
Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell. 1987 Apr 24; 49(2):273-80.
Score: 0.004
-
Marrack P, McDuffie M, Born W, Blackman M, Hannum C, Kappler J. The T cell receptor: its repertoire and role in thymocyte development. Adv Exp Med Biol. 1987; 213:1-12.
Score: 0.003
-
Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. J Exp Med. 2006 Dec 25; 203(13):2953-61.
Score: 0.003
-
Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 2006 Dec; 25(6):929-40.
Score: 0.003
-
McDuffie M, Born W, Marrack P, Kappler J. The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8728-32.
Score: 0.003
-
Born W, Rathbun G, Tucker P, Marrack P, Kappler J. Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. Science. 1986 Oct 24; 234(4775):479-82.
Score: 0.003
-
Jørgensen TN, Thurman J, Izui S, Falta MT, Metzger TE, Flannery SA, Kappler J, Marrack P, Kotzin BL. Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice. Genes Immun. 2006 Oct; 7(7):555-67.
Score: 0.003
-
Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12063-8.
Score: 0.003
-
Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunol Rev. 2006 Jun; 211:49-57.
Score: 0.003
-
Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. J Exp Med. 2006 May 15; 203(5):1147-52.
Score: 0.003
-
Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. J Exp Med. 2006 Mar 20; 203(3):731-41.
Score: 0.003
-
Marrack P, Kappler J. The T cell and its receptor. Sci Am. 1986 Feb; 254(2):36-45.
Score: 0.003
-
Kawahara DJ, Marrack P, Kappler JW. H-2-linked Ir gene control of VH determinant(s)-specific helper T cells. J Mol Cell Immunol. 1986; 2(5):255-64.
Score: 0.003
-
Marrack P, Kappler J. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol. 1986; 38:1-30.
Score: 0.003
-
Marrack P, Born W, Roehm N, Farr A, Kappler J. T cell receptors in the thymus. Biochem Soc Symp. 1986; 51:197-204.
Score: 0.003
-
Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. Int Arch Allergy Immunol. 2006; 139(1):63-74.
Score: 0.003
-
Farr AG, Anderson SK, Marrack P, Kappler J. Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ. Cell. 1985 Dec; 43(2 Pt 1):543-50.
Score: 0.003
-
Roehm NW, Carbone A, Kushnir E, Taylor BA, Riblet RJ, Marrack P, Kappler JW. The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol. 1985 Sep; 135(3):2176-82.
Score: 0.003
-
Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunol Rev. 2005 Jun; 205:170-89.
Score: 0.003
-
Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 2005 Jun; 52(6):1885-96.
Score: 0.003
-
Czitrom AA, Edwards S, Phillips RA, Bosma MJ, Marrack P, Kappler JW. The function of antigen-presenting cells in mice with severe combined immunodeficiency. J Immunol. 1985 Apr; 134(4):2276-80.
Score: 0.003
-
Grey HM, Chesnut RW, Shimonkevitz R, Marrack P, Kappler J. Mechanisms of antigen processing and presentation. Immunobiology. 1984 Dec; 168(3-5):202-12.
Score: 0.003
-
Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P. Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7. J Exp Med. 2004 Nov 01; 200(9):1179-87.
Score: 0.003
-
Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science. 2004 Jun 18; 304(5678):1808-10.
Score: 0.003
-
Leibson HJ, Gefter M, Zlotnik A, Marrack P, Kappler JW. Role of gamma-interferon in antibody-producing responses. Nature. 1984 Jun 28-Jul 4; 309(5971):799-801.
Score: 0.003
-
Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7681-6.
Score: 0.003
-
Huseby E, Kappler J, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? Eur J Immunol. 2004 May; 34(5):1243-50.
Score: 0.003
-
Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 2004 Aug 01; 104(3):735-43.
Score: 0.003
-
Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):1004-9.
Score: 0.003
-
Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15035-40.
Score: 0.003
-
Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med. 1983 Nov 01; 158(5):1635-46.
Score: 0.003
-
Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 1983 Nov; 35(1):295-302.
Score: 0.003
-
Sunshine GH, Gold DP, Wortis HH, Marrack P, Kappler JW. Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas. J Exp Med. 1983 Nov 01; 158(5):1745-50.
Score: 0.003
-
Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, Fitch F, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med. 1983 Oct 01; 158(4):1077-91.
Score: 0.003
-
Endres RO, Marrack P, Kappler JW. An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region. J Immunol. 1983 Oct; 131(4):1656-62.
Score: 0.003
-
Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell. 1983 Oct; 34(3):727-37.
Score: 0.003
-
Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11565-70.
Score: 0.003
-
Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nat Immunol. 2003 Oct; 4(10):974-81.
Score: 0.003
-
Roehm NW, Marrack P, Kappler JW. Helper signals in the plaque-forming cell response to protein-bound haptens. J Exp Med. 1983 Aug 01; 158(2):317-33.
Score: 0.003
-
Zlotnik A, Roberts WK, Vasil A, Blumenthal E, Larosa F, Leibson HJ, Endres RO, Graham SD, White J, Hill J, Henson P, Klein JR, Bevan MJ, Marrack P, Kappler JW. Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine? J Immunol. 1983 Aug; 131(2):794-800.
Score: 0.003
-
Marrack P, Skidmore B, Kappler JW. Binding of antigen-specific, H-2-restricted T cell hybridomas to antigen-pulsed adherent cell monolayers. J Immunol. 1983 May; 130(5):2088-92.
Score: 0.003
-
White J, Haskins KM, Marrack P, Kappler J. Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol. 1983 Mar; 130(3):1033-7.
Score: 0.003
-
Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. J Clin Invest. 2003 Mar; 111(5):575-81.
Score: 0.003
-
Marrack P, Kappler J. Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. J Exp Med. 1983 Feb 01; 157(2):404-18.
Score: 0.003
-
Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Curr Opin Immunol. 2003 Feb; 15(1):120-7.
Score: 0.003
-
Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev. 1983; 74:29-56.
Score: 0.003
-
Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunol Rev. 1983; 76:131-45.
Score: 0.003
-
Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Ann N Y Acad Sci. 2002 Dec; 975:114-31.
Score: 0.003
-
Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P. RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process. Immunity. 2002 Nov; 17(5):605-15.
Score: 0.003
-
Liebson HJ, Marrack P, Kappler J. B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells. J Immunol. 1982 Oct; 129(4):1398-402.
Score: 0.003
-
Freiberg BA, Kupfer H, Maslanik W, Delli J, Kappler J, Zaller DM, Kupfer A. Staging and resetting T cell activation in SMACs. Nat Immunol. 2002 Oct; 3(10):911-7.
Score: 0.003
-
Jordan MB, van Rooijen N, Izui S, Kappler J, Marrack P. Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. Blood. 2003 Jan 15; 101(2):594-601.
Score: 0.003
-
Roehm NW, Marrack P, Kappler JW. Antigen-specific, H-2-restricted helper T cell hybridomas. J Exp Med. 1982 Jul 01; 156(1):191-204.
Score: 0.003
-
Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8832-7.
Score: 0.003
-
Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Curr Opin Immunol. 2002 Jun; 14(3):354-9.
Score: 0.003
-
Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 2002 Jun; 16(6):759-67.
Score: 0.003
-
Myrick C, DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P, Wakeland EK. Linkage analysis of variations in CD4:CD8 T cell subsets between C57BL/6 and DBA/2. Genes Immun. 2002 May; 3(3):144-50.
Score: 0.003
-
Marrack P, Graham SD, Kushnir E, Leibson HJ, Roehm N, Kappler JW. Nonspecific factors in B cell responses. Immunol Rev. 1982; 63:33-49.
Score: 0.002
-
de Souza AR, Swanson B, Robertson J, Bender J, Kappler J, Marrack P. Some properties of T cells in animals. Adv Exp Med Biol. 2002; 512:121-8.
Score: 0.002
-
Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol. 2001 Dec 15; 214(2):110-22.
Score: 0.002
-
Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nat Immunol. 2002 Jan; 3(1):27-32.
Score: 0.002
-
Leibson HJ, Marrack P, Kappler JW. B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med. 1981 Nov 01; 154(5):1681-93.
Score: 0.002
-
Schaefer BC, Mitchell TC, Kappler JW, Marrack P. A novel family of retroviral vectors for the rapid production of complex stable cell lines. Anal Biochem. 2001 Oct 01; 297(1):86-93.
Score: 0.002
-
Kedl RM, Jordan M, Potter T, Kappler J, Marrack P, Dow S. CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10811-6.
Score: 0.002
-
Kappler JW, Skidmore B, White J, Marrack P. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med. 1981 May 01; 153(5):1198-214.
Score: 0.002
-
Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol. 2001 May; 2(5):397-402.
Score: 0.002
-
Kersh GJ, Miley MJ, Nelson CA, Grakoui A, Horvath S, Donermeyer DL, Kappler J, Allen PM, Fremont DH. Structural and functional consequences of altering a peptide MHC anchor residue. J Immunol. 2001 Mar 01; 166(5):3345-54.
Score: 0.002
-
Lang P, Stolpa JC, Freiberg BA, Crawford F, Kappler J, Kupfer A, Cambier JC. TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science. 2001 Feb 23; 291(5508):1537-40.
Score: 0.002
-
Ku CC, Kappler J, Marrack P. The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines. J Immunol. 2001 Feb 15; 166(4):2186-93.
Score: 0.002
-
Fassò M, Anandasabapathy N, Crawford F, Kappler J, Fathman CG, Ridgway WM. T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo. J Exp Med. 2000 Dec 18; 192(12):1719-30.
Score: 0.002
-
Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays. J Exp Med. 1980 Nov 01; 152(5):1274-88.
Score: 0.002
-
Kedl RM, Rees WA, Hildeman DA, Schaefer B, Mitchell T, Kappler J, Marrack P. T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med. 2000 Oct 16; 192(8):1105-13.
Score: 0.002
-
Harwell L, Skidmore B, Marrack P, Kappler J. Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med. 1980 Oct 01; 152(4):893-904.
Score: 0.002
-
Jackisch BO, Hausser H, Schaefer L, Kappler J, Müller HW, Kresse H. Alternative exon usage of rat septins. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):180-8.
Score: 0.002
-
Ku CC, Murakami M, Sakamoto A, Kappler J, Marrack P. Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science. 2000 Apr 28; 288(5466):675-8.
Score: 0.002
-
Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. J Exp Med. 2000 Mar 20; 191(6):915-26.
Score: 0.002
-
Keller DM, Swierkosz JE, Marrack P, Kappler JW. Two types of functionally distinct, synergizing helper T cells. J Immunol. 1980 Mar; 124(3):1350-9.
Score: 0.002
-
Marrack P, Kappler JW. The two high responder haplotypes to (TG)-A--L do not cross-react in the helper T cell level. J Immunol. 1980 Feb; 124(2):1002-4.
Score: 0.002
-
White J, Kappler J, Marrack P. Production and characterization of T cell hybridomas. Methods Mol Biol. 2000; 134:185-93.
Score: 0.002
-
Swierkosz JE, Marrack P, Kappler JW. Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity. J Exp Med. 1979 Dec 01; 150(6):1293-309.
Score: 0.002
-
Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12691-6.
Score: 0.002
-
Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity. 1999 Oct; 11(4):411-21.
Score: 0.002
-
Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med. 1999 Aug 02; 190(3):367-74.
Score: 0.002
-
Swierkosz JE, Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. V. I-region control of helper T cell interaction with antigen-presenting macrophages. J Immunol. 1979 Aug; 123(2):654-9.
Score: 0.002
-
Hildeman DA, Mitchell T, Teague TK, Henson P, Day BJ, Kappler J, Marrack PC. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity. 1999 Jun; 10(6):735-44.
Score: 0.002
-
Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol. 1999 Apr 15; 162(8):4527-35.
Score: 0.002
-
Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. J Exp Med. 1979 Mar 01; 149(3):780-5.
Score: 0.002
-
Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. J Exp Med. 1999 Feb 01; 189(3):521-30.
Score: 0.002
-
Kappler JW, Marrack P. The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med. 1978 Dec 01; 148(6):1510-22.
Score: 0.002
-
Wilson NA, Wolf P, Ploegh H, Ignatowicz L, Kappler J, Marrack P. Invariant chain can bind MHC class II at a site other than the peptide binding groove. J Immunol. 1998 Nov 01; 161(9):4777-84.
Score: 0.002
-
Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages. J Exp Med. 1978 Jun 01; 147(6):1596-610.
Score: 0.002
-
Vella AT, Dow S, Potter TA, Kappler J, Marrack P. Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3810-5.
Score: 0.002
-
Hoffmann MK, Kappler JW. Two distinct mechanisms of immune suppression by antibody. Nature. 1978 Mar 02; 272(5648):64-5.
Score: 0.002
-
Swierkosz JE, Rock K, Marrack P, Kappler JW. The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 products. J Exp Med. 1978 Feb 01; 147(2):554-70.
Score: 0.002
-
Ku CC, Kotzin B, Kappler J, Marrack P. CD8+ T-cell clones in old mice. Immunol Rev. 1997 Dec; 160:139-44.
Score: 0.002
-
Liu CP, Parker D, Kappler J, Marrack P. Selection of antigen-specific T cells by a single IEk peptide combination. J Exp Med. 1997 Nov 03; 186(9):1441-50.
Score: 0.002
-
Araneo BA, Marrack P, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. VII. Conversion of T1 cells to T2 cells by antigen. J Immunol. 1977 Aug; 119(2):765-71.
Score: 0.002
-
Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
Score: 0.002
-
Vella A, Teague TK, Ihle J, Kappler J, Marrack P. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med. 1997 Jul 21; 186(2):325-30.
Score: 0.002
-
Teague TK, Marrack P, Kappler JW, Vella AT. IL-6 rescues resting mouse T cells from apoptosis. J Immunol. 1997 Jun 15; 158(12):5791-6.
Score: 0.002
-
Vella AT, Mitchell T, Groth B, Linsley PS, Green JM, Thompson CB, Kappler JW, Marrack P. CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo. J Immunol. 1997 May 15; 158(10):4714-20.
Score: 0.002
-
Ku CC, Kappler J, Marrack P. Characteristics and maintenance of CD8+ T-cell clones found in old mice. Mech Ageing Dev. 1997 Mar; 94(1-3):41-53.
Score: 0.002
-
Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1350-5.
Score: 0.002
-
Liu CP, Lin WJ, Huang M, Kappler JW, Marrack P. Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):616-21.
Score: 0.002
-
Harwell L, Marrack P, Kappler JW. Suppressor T-cell inactivation of a helper T-cell factor. Nature. 1977 Jan 06; 265(5589):57-9.
Score: 0.002
-
Horan PK, Kappler JW. Automated fluorescent analysis for cytotoxicity assays. J Immunol Methods. 1977; 18(3-4):309-16.
Score: 0.002
-
Araneo BA, Marrack PC, Kappler JW. Functional heterongeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation. J Immunol. 1976 Dec; 117(6):2131-6.
Score: 0.002
-
Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. IV. Development of a model system demonstrating responsiveness of two T cell functions to HGG in vitro. J Immunol. 1976 Nov; 117(5 Pt.2):1953-9.
Score: 0.002
-
Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. V. Unresponsiveness to HGG in vitro of these two T cell subpopulations. J Immunol. 1976 Nov; 117(5 Pt.2):1960-5.
Score: 0.002
-
Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med. 1996 Nov 01; 184(5):1619-30.
Score: 0.002
-
Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. V. Response kinetics of peripheral T cell subpopulations. J Immunol. 1976 Oct; 117(4):1233-7.
Score: 0.002
-
Ignatowicz L, Kappler J, Parker DC, Marrack P. The responses of mature T cells are not necessarily antagonized by their positively selecting peptide. J Immunol. 1996 Sep 01; 157(5):1827-31.
Score: 0.002
-
Kappler JW, Marrack PC. Helper T cells recognise antigen and macrophage surface components simultaneously. Nature. 1976 Aug 26; 262(5571):797-9.
Score: 0.002
-
Marrack P, Kappler JW. Antigen-specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T cells distinguished by their antigen sensitivities. J Immunol. 1976 May; 116(5):1373-8.
Score: 0.002
-
Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 1996 Feb 23; 84(4):521-9.
Score: 0.002
-
Vella AT, Scherer MT, Schultz L, Kappler JW, Marrack P. B cells are not essential for peripheral T-cell tolerance. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):951-5.
Score: 0.002
-
Scherer MT, Ignatowicz L, Pullen A, Kappler J, Marrack P. The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med. 1995 Nov 01; 182(5):1493-504.
Score: 0.002
-
Kappler JW, Marrack PC. Functional heterogeneity among the T-derived lymphocytes of the mouse. III. Helper and suppressor T-cells activated by concanavalin A. Cell Immunol. 1975 Jul; 18(1):9-20.
Score: 0.002
-
Ignatowicz L, Winslow G, Bill J, Kappler J, Marrack P. Cell surface expression of class II MHC proteins bound by a single peptide. J Immunol. 1995 Apr 15; 154(8):3852-62.
Score: 0.002
-
Marrack PC, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells. J Immunol. 1975 Mar; 114(3):1116-25.
Score: 0.002
-
Vella AT, McCormack JE, Linsley PS, Kappler JW, Marrack P. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity. 1995 Mar; 2(3):261-70.
Score: 0.002
-
Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. II. Sensitivity of subpopulations to anti-thymocyte serum. J Immunol. 1975 Feb; 114(2 pt 2):747-51.
Score: 0.002
-
Kappler JW, Hunter PC, Jacobs D, Lord E. Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy. J Immunol. 1974 Jul; 113(1):27-38.
Score: 0.001
-
McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2086-90.
Score: 0.001
-
Kappler JW. A micro-technique for hemolytic plaque assays. J Immunol. 1974 Mar; 112(3):1271-4.
Score: 0.001
-
Hugo P, Kappler JW, Godfrey DI, Marrack PC. Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion. J Immunol. 1994 Feb 01; 152(3):1022-31.
Score: 0.001
-
Ignatowicz L, Kappler JW, Marrack P, Scherer MT. Identification of two V beta 7-specific viral superantigens. J Immunol. 1994 Jan 01; 152(1):65-71.
Score: 0.001
-
Callahan JE, Kappler JW, Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J Immunol. 1993 Dec 15; 151(12):6657-69.
Score: 0.001
-
Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II. J Exp Med. 1993 Dec 01; 178(6):2173-83.
Score: 0.001
-
Hugo P, Kappler JW, McCormack JE, Marrack P. Fibroblasts can induce thymocyte positive selection in vivo. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10335-9.
Score: 0.001
-
Kappler JW, van der Hoven A, Dharmarajan U, Hoffmann M. Regulation of the immune response. IV. Antibody-mediated suppression of the immune response to haptens and heterologous erythrocyte antigens in vitro. J Immunol. 1973 Oct; 111(4):1228-35.
Score: 0.001
-
Hugo P, Kappler JW, Marrack PC. Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? Immunol Rev. 1993 Oct; 135:133-55.
Score: 0.001
-
Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ. Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun. 1993 Aug; 61(8):3175-83.
Score: 0.001
-
Kappler JW, Hoffmann M. Regulation of the immune response. 3. Kinetic differences between thymus- and bone marrow- derived lymphocytes in the proliferative response to heterologous erythrocytes. J Exp Med. 1973 Jun 01; 137(6):1325-37.
Score: 0.001
-
McCormack JE, Callahan JE, Kappler J, Marrack PC. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J Immunol. 1993 May 01; 150(9):3785-92.
Score: 0.001
-
Hoffmann M, Kappler JW. Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen. J Exp Med. 1973 Mar 01; 137(3):721-39.
Score: 0.001
-
Scherer MT, Ignatowicz L, Winslow GM, Kappler JW, Marrack P. Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol. 1993; 9:101-28.
Score: 0.001
-
Kotzin BL, Leung DY, Kappler J, Marrack P. Superantigens and their potential role in human disease. Adv Immunol. 1993; 54:99-166.
Score: 0.001
-
Hugo P, Kappler JW, Godfrey DI, Marrack PC. A cell line that can induce thymocyte positive selection. Nature. 1992 Dec 17; 360(6405):679-82.
Score: 0.001
-
Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 1992 Nov 27; 71(5):719-30.
Score: 0.001
-
Finkel TH, Kappler JW, Marrack PC. Immature thymocytes are protected from deletion early in ontogeny. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3372-4.
Score: 0.001
-
Ignatowicz L, Kappler J, Marrack P. The effects of chronic infection with a superantigen-producing virus. J Exp Med. 1992 Apr 01; 175(4):917-23.
Score: 0.001
-
Pullen AM, Choi Y, Kushnir E, Kappler J, Marrack P. The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med. 1992 Jan 01; 175(1):41-7.
Score: 0.001
-
Hoffmann M, Kappler JW. The antigen specificity of thymus-derived helper cells. J Immunol. 1972 Jan; 108(1):261-3.
Score: 0.001
-
McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cell Immunol. 1991 Dec; 138(2):413-22.
Score: 0.001
-
Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8357-61.
Score: 0.001
-
Kappler JW, Hoffmann M, Dutton RW. Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med. 1971 Sep 01; 134(3 Pt 1):577-87.
Score: 0.001
-
Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P. Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6682-6.
Score: 0.001
-
Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 1991 Mar 21; 350(6315):203-7.
Score: 0.001
-
Herman A, Kappler JW, Marrack P, Pullen AM. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol. 1991; 9:745-72.
Score: 0.001
-
Blackman MA, Kappler JW, Marrack P. Multiple mechanisms of T cell tolerance to Mls-1a. Adv Exp Med Biol. 1991; 292:159-65.
Score: 0.001
-
McCormack JE, Kappler J, Marrack P, Westcott JY. Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture. J Immunol. 1991 Jan 01; 146(1):239-43.
Score: 0.001
-
Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 1990 Sep 21; 62(6):1115-21.
Score: 0.001
-
Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med. 1990 Sep 01; 172(3):709-17.
Score: 0.001
-
Blackman M, Kappler J, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells. Science. 1990 Jun 15; 248(4961):1335-41.
Score: 0.001
-
Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science. 1990 Jun 08; 248(4960):1227-30.
Score: 0.001
-
Blackman MA, Burgert HG, Gerhard-Burgert H, Woodland DL, Palmer E, Kappler JW, Marrack P. A role for clonal inactivation in T cell tolerance to Mls-1a. Nature. 1990 Jun 07; 345(6275):540-2.
Score: 0.001
-
Callahan JE, Herman A, Kappler JW, Marrack P. Stimulation of B10.BR T cells with superantigenic staphylococcal toxins. J Immunol. 1990 Apr 01; 144(7):2473-9.
Score: 0.001
-
Kappler JW. The kinetics of DNA methylation in cultures of a mouse adrenal cell line. J Cell Physiol. 1970 Feb; 75(1):21-31.
Score: 0.001
-
Golde WT, McDuffie M, Kappler J, Marrack P. Identification of a new cell surface glycoprotein with accessory function in murine T cell responses. J Immunol. 1990 Feb 01; 144(3):804-10.
Score: 0.001
-
Pullen AM, Potts W, Wakeland EK, Kappler J, Marrack P. Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J Exp Med. 1990 Jan 01; 171(1):49-62.
Score: 0.001
-
White J, Blackman M, Bill J, Kappler J, Marrack P, Gold DP, Born W. Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol. 1989 Sep 15; 143(6):1822-5.
Score: 0.001
-
Kotzin BL, Kappler JW, Marrack PC, Herron LR. T cell tolerance to self antigens in New Zealand hybrid mice with lupus-like disease. J Immunol. 1989 Jul 01; 143(1):89-94.
Score: 0.001
-
Finkel TH, Marrack P, Kappler JW, Kubo RT, Cambier JC. Alpha beta T cell receptor and CD3 transduce different signals in immature T cells. Implications for selection and tolerance. J Immunol. 1989 May 01; 142(9):3006-12.
Score: 0.001
-
Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol. 1989 Apr 15; 142(8):2736-42.
Score: 0.001
-
Pullen AM, Kappler JW, Marrack P. Tolerance to self antigens shapes the T-cell repertoire. Immunol Rev. 1989 Feb; 107:125-39.
Score: 0.001
-
White J, Herman A, Pullen AM, Kubo R, Kappler JW, Marrack P. The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell. 1989 Jan 13; 56(1):27-35.
Score: 0.001
-
Yague J, Blackman M, Born W, Marrack P, Kappler J, Palmer E. The structure of V alpha and J alpha segments in the mouse. Nucleic Acids Res. 1988 Dec 09; 16(23):11355-64.
Score: 0.001
-
McDuffie M, Roehm N, Kappler JW, Marrack P. Involvement of major histocompatibility complex products in tolerance induction in the thymus. J Immunol. 1988 Sep 15; 141(6):1840-7.
Score: 0.001
-
Fenton RG, Marrack P, Kappler JW, Kanagawa O, Seidman JG. Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene. Science. 1988 Aug 26; 241(4869):1089-92.
Score: 0.001
-
Gay D, Buus S, Pasternak J, Kappler J, Marrack P. The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia. Proc Natl Acad Sci U S A. 1988 Aug; 85(15):5629-33.
Score: 0.001
-
van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 1988 May 06; 53(3):357-70.
Score: 0.001
-
Born W, White J, Kappler J, Marrack P. Rearrangement of IgH genes in normal thymocyte development. J Immunol. 1988 May 01; 140(9):3228-32.
Score: 0.001
-
Blackman MA, Kappler JW, Marrack P. T-cell specificity and repertoire. Immunol Rev. 1988 Jan; 101:5-19.
Score: 0.001
-
Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking. Nature. 1987 Nov 12-18; 330(6144):179-81.
Score: 0.001
-
Born W, McDuffie M, Roehm N, Kushnir E, White J, Thorpe D, Stefano J, Kappler J, Marrack P. Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J Immunol. 1987 Feb 15; 138(4):999-1008.
Score: 0.001
-
Gay D, Kappler J, Marrack P. L3T4 interacts with class II molecules on target cells. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):127-31.
Score: 0.001
-
Golde WT, Gay D, Kappler J, Marrack P. The role of LFA-1 in class II restricted, antigen-specific T-cell responses. Cell Immunol. 1986 Nov; 103(1):73-83.
Score: 0.001
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Gay D, Coeshott C, Golde W, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. IX. Role of accessory molecules in recognition of antigen plus isolated IA. J Immunol. 1986 Mar 15; 136(6):2026-32.
Score: 0.001
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Yagüe J, White J, Coleclough C, Kappler J, Palmer E, Marrack P. The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell. 1985 Aug; 42(1):81-7.
Score: 0.001
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Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M. Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 01; 161(5):1219-24.
Score: 0.001
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Born W, Yagüe J, Palmer E, Kappler J, Marrack P. Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A. 1985 May; 82(9):2925-9.
Score: 0.001
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Golde WT, Kappler JW, Greenstein J, Malissen B, Hood L, Marrack P. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. J Exp Med. 1985 Mar 01; 161(3):635-40.
Score: 0.001
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Zlotnik A, Shimonkevitz R, Kappler J, Marrack P. Effect of prostaglandin E2 on the gamma-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas. Cell Immunol. 1985 Jan; 90(1):154-66.
Score: 0.001
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Watts TH, Brian AA, Kappler JW, Marrack P, McConnell HM. Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7564-8.
Score: 0.001
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Shimonkevitz R, Colon S, Kappler JW, Marrack P, Grey HM. Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol. 1984 Oct; 133(4):2067-74.
Score: 0.001
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Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunol Rev. 1984 Oct; 81:161-76.
Score: 0.001
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Roehm N, Herron L, Cambier J, DiGuisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell. 1984 Sep; 38(2):577-84.
Score: 0.001
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Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, Cambier JC. Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med. 1984 Sep 01; 160(3):679-94.
Score: 0.001
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Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med. 1984 Aug 01; 160(2):452-71.
Score: 0.001
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Greenstein JL, Kappler J, Marrack P, Burakoff SJ. The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med. 1984 Apr 01; 159(4):1213-24.
Score: 0.001
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Folsom V, Gold DP, White J, Marrack P, Kappler J, Tonegawa S. Functional and inducible expression of a transfected murine class II major histocompatibility complex gene. Proc Natl Acad Sci U S A. 1984 Apr; 81(7):2045-9.
Score: 0.001
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Malissen B, Price MP, Goverman JM, McMillan M, White J, Kappler J, Marrack P, Pierres A, Pierres M, Hood L. Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell. 1984 Feb; 36(2):319-27.
Score: 0.001
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Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. Annu Rev Immunol. 1984; 2:51-66.
Score: 0.001
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Zlotnik A, Shimonkevitz RP, Gefter ML, Kappler J, Marrack P. Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. J Immunol. 1983 Dec; 131(6):2814-20.
Score: 0.001
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Wilde DB, Marrack P, Kappler J, Dialynas DP, Fitch FW. Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J Immunol. 1983 Nov; 131(5):2178-83.
Score: 0.001
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Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
Score: 0.001
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Shimonkevitz R, Kappler J, Marrack P, Grey H. Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med. 1983 Aug 01; 158(2):303-16.
Score: 0.001
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Daughety TW, Marrack P, Kappler JW, Chiller JM. The capacity of murine alveolar macrophages to stimulate antigen-dependent T-lymphocyte activation and proliferation. Cell Immunol. 1983 Jul 15; 79(2):374-82.
Score: 0.001
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Kronenberg M, Kraig E, Siu G, Kapp JA, Kappler J, Marrack P, Pierce CW, Hood L. Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts. J Exp Med. 1983 Jul 01; 158(1):210-27.
Score: 0.001
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Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med. 1983 Apr 01; 157(4):1149-69.
Score: 0.001
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Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens. J Immunol. 1983 Feb; 130(2):781-4.
Score: 0.001
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Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med. 1983 Feb 01; 157(2):600-12.
Score: 0.001
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Walker E, Warner NL, Chesnut R, Kappler J, Marrack P. Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol. 1982 May; 128(5):2164-9.
Score: 0.001
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Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A role for T cell helper factors in antibody responses to "T-independent" antigens. Lymphokine Res. 1982; 1(4):99-106.
Score: 0.001
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Greenstein JL, Lord E, Kappler JW, Marrack PC. Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help. J Exp Med. 1981 Nov 01; 154(5):1608-17.
Score: 0.001
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Greenstein JL, Lord EM, Horan P, Kappler JW, Marrack P. Functional subsets of B cells defined by quantitative differences in surface I-A. J Immunol. 1981 Jun; 126(6):2419-23.
Score: 0.001
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Greenstein JL, Leary J, Horan P, Kappler JW, Marrack P. Flow sorting of antigen-binding B cell subsets. J Immunol. 1980 Mar; 124(3):1472-81.
Score: 0.001
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Berkarda B, Marrack P, Kappler JW, Bakemeier RF. Effects of warfarin administration on the immune response of mice. Arzneimittelforschung. 1978; 28(8):1407-10.
Score: 0.000
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Harwell L, Kappler JW, Marrack P. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources. J Immunol. 1976 May; 116(5):1379-84.
Score: 0.000
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Burns FD, Marrack PC, Kappler JW, Janeway CA. Functional heterogeneity among the T-derived lymphocytes of the mouse. IV. Nature of spontaneously induced suppressor cells. J Immunol. 1975 Apr; 114(4):1345-7.
Score: 0.000
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Hunter PM, Kappler JW, Kettman JR. The frequency and activity of single helper T cells. J Immunol. 1974 Sep; 113(3):830-4.
Score: 0.000
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Hoffmann MK, Kappler JW, Hirst JA, Oettgen HF. Regulation of the immune response. V. Antibody-mediated inhibition of T and B cell cooperation in the in vitro response to red cell antigens. Eur J Immunol. 1974 Apr; 4(4):282-6.
Score: 0.000
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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