Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

John Kappler to Humans

This is a "connection" page, showing publications John Kappler has written about Humans.

 
Connection Strength
 
 
 
0.378
 
  1. Reed BK, Kappler JW. Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes. Front Immunol. 2021; 12:669986.
    View in: PubMed
    Score: 0.019
  2. Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 03; 158(1):132-42.
    View in: PubMed
    Score: 0.012
  3. Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harb Perspect Med. 2012 Sep 01; 2(9):a007765.
    View in: PubMed
    Score: 0.010
  4. Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11893-7.
    View in: PubMed
    Score: 0.008
  5. Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Curr Opin Immunol. 2008 Apr; 20(2):203-7.
    View in: PubMed
    Score: 0.008
  6. Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 2008 Mar; 28(3):324-34.
    View in: PubMed
    Score: 0.008
  7. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203.
    View in: PubMed
    Score: 0.007
  8. Peyerl FW, Dai S, Murphy GA, Crawford F, White J, Marrack P, Kappler JW. Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex. Cell Death Differ. 2007 Mar; 14(3):447-52.
    View in: PubMed
    Score: 0.007
  9. Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol Rev. 2006 Apr; 210:156-70.
    View in: PubMed
    Score: 0.007
  10. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol. 2006 Mar 01; 176(5):2683-90.
    View in: PubMed
    Score: 0.007
  11. Boder ET, Bill JR, Nields AW, Marrack PC, Kappler JW. Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide. Biotechnol Bioeng. 2005 Nov 20; 92(4):485-91.
    View in: PubMed
    Score: 0.006
  12. Marrack P, Kappler J. Control of T cell viability. Annu Rev Immunol. 2004; 22:765-87.
    View in: PubMed
    Score: 0.006
  13. Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. J Exp Med. 2003 Mar 03; 197(5):567-74.
    View in: PubMed
    Score: 0.005
  14. Liu H, Wei P, Aviszus K, Zhang Q, Linderberger J, Yang J, Liu J, Chen Z, Waheed H, Reynoso L, Downey GP, Frankel SK, Kappler JW, Marrack P, Zhang G. The Receptor Binding Domain of SARS-CoV-2 Lambda Variant Has a Better Chance Than the Delta Variant in Evading BNT162b2 COVID-19 mRNA Vaccine-Induced Humoral Immunity. Int J Mol Sci. 2022 Sep 26; 23(19).
    View in: PubMed
    Score: 0.005
  15. Liu H, Wei P, Kappler JW, Marrack P, Zhang G. SARS-CoV-2 Variants of Concern and Variants of Interest Receptor Binding Domain Mutations and Virus Infectivity. Front Immunol. 2022; 13:825256.
    View in: PubMed
    Score: 0.005
  16. Ramos SA, Morton JJ, Yadav P, Reed B, Alizadeh SI, Shilleh AH, Perrenoud L, Jaggers J, Kappler J, Jimeno A, Russ HA. Generation of functional human thymic cells from induced pluripotent stem cells. J Allergy Clin Immunol. 2022 02; 149(2):767-781.e6.
    View in: PubMed
    Score: 0.005
  17. Marrack P, Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? J Immunol. 2001 Jul 15; 167(2):617-21.
    View in: PubMed
    Score: 0.005
  18. Falta MT, Crawford JC, Tinega AN, Landry LG, Crawford F, Mack DG, Martin AK, Atif SM, Li L, Santos RG, Nakayama M, Kappler JW, Maier LA, Thomas PG, Pinilla C, Fontenot AP. Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation. J Clin Invest. 2021 05 03; 131(9).
    View in: PubMed
    Score: 0.005
  19. Liu H, Zhang Q, Wei P, Chen Z, Aviszus K, Yang J, Downing W, Jiang C, Liang B, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. The basis of a more contagious 501Y.V1 variant of SARS-CoV-2. Cell Res. 2021 06; 31(6):720-722.
    View in: PubMed
    Score: 0.005
  20. Bai P, Zhou Q, Wei P, Bai H, Chan SK, Kappler JW, Marrack P, Yin L. Rational discovery of a cancer neoepitope harboring the KRAS G12D driver mutation. Sci China Life Sci. 2021 12; 64(12):2144-2152.
    View in: PubMed
    Score: 0.005
  21. Bai P, Li Y, Zhou Q, Xia J, Wei PC, Deng H, Wu M, Chan SK, Kappler JW, Zhou Y, Tran E, Marrack P, Yin L. Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology. 2021 01 15; 10(1):1868130.
    View in: PubMed
    Score: 0.005
  22. Liu H, Wei P, Zhang Q, Chen Z, Aviszus K, Downing W, Peterson S, Reynoso L, Downey GP, Frankel SK, Kappler J, Marrack P, Zhang G. 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro. MAbs. 2021 Jan-Dec; 13(1):1919285.
    View in: PubMed
    Score: 0.005
  23. Phalke S, Aviszus K, Rubtsova K, Rubtsov A, Barkes B, Powers L, Warner B, Crooks JL, Kappler JW, Fern?ndez-P?rez ER, Maier LA, Hamzeh N, Marrack P. Age-associated B Cells Appear in Patients with Granulomatous Lung Diseases. Am J Respir Crit Care Med. 2020 10 01; 202(7):1013-1023.
    View in: PubMed
    Score: 0.005
  24. Liu H, Ramachandran S, Fong N, Phang T, Lee S, Parsa P, Liu X, Harmacek L, Danhorn T, Song T, Oh S, Zhang Q, Chen Z, Zhang Q, Tu TH, Happoldt C, O'Conner B, Janknecht R, Li CY, Marrack P, Kappler J, Leach S, Zhang G. JMJD5 couples with CDK9 to release the paused RNA polymerase II. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19888-19895.
    View in: PubMed
    Score: 0.004
  25. Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nat Immunol. 2000 Aug; 1(2):107-11.
    View in: PubMed
    Score: 0.004
  26. Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Curr Opin Immunol. 2000 Apr; 12(2):206-9.
    View in: PubMed
    Score: 0.004
  27. Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):291-6.
    View in: PubMed
    Score: 0.004
  28. Clayton GM, White J, Lee S, Kappler JW, Chan SK. Structural characteristics of lipocalin allergens: Crystal structure of the immunogenic dog allergen Can f 6. PLoS One. 2019; 14(9):e0213052.
    View in: PubMed
    Score: 0.004
  29. Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
    View in: PubMed
    Score: 0.004
  30. Kotzin BL, Kappler J. Targeting the T cell receptor in rheumatoid arthritis. Arthritis Rheum. 1998 Nov; 41(11):1906-10.
    View in: PubMed
    Score: 0.004
  31. Williams T, Krovi HS, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama M. Development of T cell lines sensitive to antigen stimulation. J Immunol Methods. 2018 11; 462:65-73.
    View in: PubMed
    Score: 0.004
  32. Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep. 2018 02 19; 8(1):3275.
    View in: PubMed
    Score: 0.004
  33. Rozanov DV, Rozanov ND, Chiotti KE, Reddy A, Wilmarth PA, David LL, Cha SW, Woo S, Pevzner P, Bafna V, Burrows GG, Rantala JK, Levin T, Anur P, Johnson-Camacho K, Tabatabaei S, Munson DJ, Bruno TC, Slansky JE, Kappler JW, Hirano N, Boegel S, Fox BA, Egelston C, Simons DL, Jimenez G, Lee PP, Gray JW, Spellman PT. MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection. J Proteomics. 2018 03 30; 176:13-23.
    View in: PubMed
    Score: 0.004
  34. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167.
    View in: PubMed
    Score: 0.004
  35. Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7717-E7726.
    View in: PubMed
    Score: 0.004
  36. Hamad AR, Marrack P, Kappler JW. Transcytosis of staphylococcal superantigen toxins. J Exp Med. 1997 Apr 21; 185(8):1447-54.
    View in: PubMed
    Score: 0.004
  37. Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol. 1997 Apr; 9(2):250-5.
    View in: PubMed
    Score: 0.004
  38. Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes. Diabetes. 2017 03; 66(3):722-734.
    View in: PubMed
    Score: 0.003
  39. Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ, Kappler JW, Walker BD. Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion. Immunity. 2016 10 18; 45(4):917-930.
    View in: PubMed
    Score: 0.003
  40. Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE. Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR. Proc Natl Acad Sci U S A. 2016 07 19; 113(29):8272-7.
    View in: PubMed
    Score: 0.003
  41. Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 1996 May 17; 272(5264):1001-4.
    View in: PubMed
    Score: 0.003
  42. Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS. Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation. J Immunol. 2016 Jan 01; 196(1):22-7.
    View in: PubMed
    Score: 0.003
  43. Falta MT, Tinega AN, Mack DG, Bowerman NA, Crawford F, Kappler JW, Pinilla C, Fontenot AP. Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice. Mucosal Immunol. 2016 Jan; 9(1):218-28.
    View in: PubMed
    Score: 0.003
  44. Nakayama M, McDaniel K, Fitzgerald-Miller L, Kiekhaefer C, Snell-Bergeon JK, Davidson HW, Rewers M, Yu L, Gottlieb P, Kappler JW, Michels A. Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):4429-34.
    View in: PubMed
    Score: 0.003
  45. Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S. Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease. Science. 2014 Oct 17; 346(6207):363-8.
    View in: PubMed
    Score: 0.003
  46. Yang J, Chow IT, Sosinowski T, Torres-Chinn N, Greenbaum CJ, James EA, Kappler JW, Davidson HW, Kwok WW. Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14840-5.
    View in: PubMed
    Score: 0.003
  47. Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8553-8.
    View in: PubMed
    Score: 0.003
  48. Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the a? T cell receptor. J Mol Med (Berl). 2014 Jul; 92(7):735-41.
    View in: PubMed
    Score: 0.003
  49. Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994 May 12; 369(6476):151-4.
    View in: PubMed
    Score: 0.003
  50. Bowerman NA, Falta MT, Mack DG, Wehrmann F, Crawford F, Mroz MM, Maier LA, Kappler JW, Fontenot AP. Identification of multiple public TCR repertoires in chronic beryllium disease. J Immunol. 2014 May 15; 192(10):4571-80.
    View in: PubMed
    Score: 0.003
  51. Marrack P, Kappler J. Subversion of the immune system by pathogens. Cell. 1994 Jan 28; 76(2):323-32.
    View in: PubMed
    Score: 0.003
  52. Marrack P, Kappler JW. How the immune system recognizes the body. Sci Am. 1993 Sep; 269(3):80-3, 86-9.
    View in: PubMed
    Score: 0.003
  53. Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. J Exp Med. 2013 Jul 01; 210(7):1403-18.
    View in: PubMed
    Score: 0.003
  54. McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1122-31.
    View in: PubMed
    Score: 0.003
  55. Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions. Immunol Rev. 1993 Feb; 131:79-92.
    View in: PubMed
    Score: 0.003
  56. Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein Cell. 2013 Jan; 4(1):8-16.
    View in: PubMed
    Score: 0.003
  57. Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60.
    View in: PubMed
    Score: 0.003
  58. Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18517-22.
    View in: PubMed
    Score: 0.003
  59. Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to a? T cell receptor specificity. Immunity. 2011 Oct 28; 35(4):526-35.
    View in: PubMed
    Score: 0.002
  60. Bowerman NA, Falta MT, Mack DG, Kappler JW, Fontenot AP. Mutagenesis of beryllium-specific TCRs suggests an unusual binding topology for antigen recognition. J Immunol. 2011 Oct 01; 187(7):3694-703.
    View in: PubMed
    Score: 0.002
  61. Kenyon KD, Cole C, Crawford F, Kappler JW, Thurman JM, Bratton DL, Boackle SA, Henson PM. IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity. J Immunol. 2011 Sep 01; 187(5):2101-11.
    View in: PubMed
    Score: 0.002
  62. Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c? B-cell population is important for the development of autoimmunity. Blood. 2011 Aug 04; 118(5):1305-15.
    View in: PubMed
    Score: 0.002
  63. MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7914-9.
    View in: PubMed
    Score: 0.002
  64. Kappler J, Leinekugel P, Conzelmann E, Kleijer WJ, Kohlsch?tter A, T?nnesen T, Rochel M, Freycon F, Propping P. Genotype-phenotype relationship in various degrees of arylsulfatase A deficiency. Hum Genet. 1991 Mar; 86(5):463-70.
    View in: PubMed
    Score: 0.002
  65. Hong X, Zang J, White J, Wang C, Pan CH, Zhao R, Murphy RC, Dai S, Henson P, Kappler JW, Hagman J, Zhang G. Interaction of JMJD6 with single-stranded RNA. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14568-72.
    View in: PubMed
    Score: 0.002
  66. Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 1990 Aug 02; 346(6283):471-3.
    View in: PubMed
    Score: 0.002
  67. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 May 11; 248(4956):705-11.
    View in: PubMed
    Score: 0.002
  68. Falta MT, Bowerman NA, Dai S, Kappler JW, Fontenot AP. Linking genetic susceptibility and T cell activation in beryllium-induced disease. Proc Am Thorac Soc. 2010 May; 7(2):126-9.
    View in: PubMed
    Score: 0.002
  69. Stadinski B, Kappler J, Eisenbarth GS. Molecular targeting of islet autoantigens. Immunity. 2010 Apr 23; 32(4):446-56.
    View in: PubMed
    Score: 0.002
  70. McKee AS, MacLeod MK, Kappler JW, Marrack P. Immune mechanisms of protection: can adjuvants rise to the challenge? BMC Biol. 2010 Apr 12; 8:37.
    View in: PubMed
    Score: 0.002
  71. Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30.
    View in: PubMed
    Score: 0.002
  72. MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 2010 May; 130(1):10-5.
    View in: PubMed
    Score: 0.002
  73. Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmun Rev. 2010 May; 9(7):494-8.
    View in: PubMed
    Score: 0.002
  74. Marrack P, Kappler JW. The T cell receptors. Chem Immunol. 1990; 49:69-81.
    View in: PubMed
    Score: 0.002
  75. Macdonald WA, Chen Z, Gras S, Archbold JK, Tynan FE, Clements CS, Bharadwaj M, Kjer-Nielsen L, Saunders PM, Wilce MC, Crawford F, Stadinsky B, Jackson D, Brooks AG, Purcell AW, Kappler JW, Burrows SR, Rossjohn J, McCluskey J. T cell allorecognition via molecular mimicry. Immunity. 2009 Dec 18; 31(6):897-908.
    View in: PubMed
    Score: 0.002
  76. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8941-5.
    View in: PubMed
    Score: 0.002
  77. Kappler J, Kotzin B, Herron L, Gelfand EW, Bigler RD, Boylston A, Carrel S, Posnett DN, Choi Y, Marrack P. V beta-specific stimulation of human T cells by staphylococcal toxins. Science. 1989 May 19; 244(4906):811-3.
    View in: PubMed
    Score: 0.002
  78. MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Semin Immunol. 2009 Apr; 21(2):53-61.
    View in: PubMed
    Score: 0.002
  79. Marrack P, Kappler J. The T-cell repertoire for antigen and MHC. Immunol Today. 1988 Oct; 9(10):308-15.
    View in: PubMed
    Score: 0.002
  80. Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008 Feb; 45(3):599-606.
    View in: PubMed
    Score: 0.002
  81. Marrack P, Kappler J. The T cell receptor. Science. 1987 Nov 20; 238(4830):1073-9.
    View in: PubMed
    Score: 0.002
  82. Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. J Immunol. 2007 Sep 15; 179(6):3417-24.
    View in: PubMed
    Score: 0.002
  83. Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J, et al. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 1987 Aug 13-19; 328(6131):626-9.
    View in: PubMed
    Score: 0.002
  84. Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Curr Opin Immunol. 2007 Oct; 19(5):516-21.
    View in: PubMed
    Score: 0.002
  85. Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest. 2007 May; 117(5):1270-81.
    View in: PubMed
    Score: 0.002
  86. Clambey ET, Kappler JW, Marrack P. CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome. Exp Gerontol. 2007 May; 42(5):407-11.
    View in: PubMed
    Score: 0.002
  87. Marrack P, McDuffie M, Born W, Blackman M, Hannum C, Kappler J. The T cell receptor: its repertoire and role in thymocyte development. Adv Exp Med Biol. 1987; 213:1-12.
    View in: PubMed
    Score: 0.002
  88. J?rgensen TN, Thurman J, Izui S, Falta MT, Metzger TE, Flannery SA, Kappler J, Marrack P, Kotzin BL. Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice. Genes Immun. 2006 Oct; 7(7):555-67.
    View in: PubMed
    Score: 0.002
  89. Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunol Rev. 2006 Jun; 211:49-57.
    View in: PubMed
    Score: 0.002
  90. Marrack P, Kappler J. The T cell and its receptor. Sci Am. 1986 Feb; 254(2):36-45.
    View in: PubMed
    Score: 0.002
  91. Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. Int Arch Allergy Immunol. 2006; 139(1):63-74.
    View in: PubMed
    Score: 0.002
  92. Marrack P, Kappler J. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol. 1986; 38:1-30.
    View in: PubMed
    Score: 0.002
  93. Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunol Rev. 2005 Jun; 205:170-89.
    View in: PubMed
    Score: 0.002
  94. Sim GK, Yag?e J, Nelson J, Marrack P, Palmer E, Augustin A, Kappler J. Primary structure of human T-cell receptor alpha-chain. Nature. 1984 Dec 20-1985 Jan 2; 312(5996):771-5.
    View in: PubMed
    Score: 0.002
  95. Huseby E, Kappler J, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? Eur J Immunol. 2004 May; 34(5):1243-50.
    View in: PubMed
    Score: 0.001
  96. Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 2004 Aug 01; 104(3):735-43.
    View in: PubMed
    Score: 0.001
  97. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 1983 Nov; 35(1):295-302.
    View in: PubMed
    Score: 0.001
  98. Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, Fitch F, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med. 1983 Oct 01; 158(4):1077-91.
    View in: PubMed
    Score: 0.001
  99. Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11565-70.
    View in: PubMed
    Score: 0.001
  100. Marrack P, Skidmore B, Kappler JW. Binding of antigen-specific, H-2-restricted T cell hybridomas to antigen-pulsed adherent cell monolayers. J Immunol. 1983 May; 130(5):2088-92.
    View in: PubMed
    Score: 0.001
  101. Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. J Clin Invest. 2003 Mar; 111(5):575-81.
    View in: PubMed
    Score: 0.001
  102. Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev. 1983; 74:29-56.
    View in: PubMed
    Score: 0.001
  103. Hildeman DA, Zhu Y, Mitchell TC, Kappler J, Marrack P. Molecular mechanisms of activated T cell death in vivo. Curr Opin Immunol. 2002 Jun; 14(3):354-9.
    View in: PubMed
    Score: 0.001
  104. Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G. Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell. 2002 Feb 08; 108(3):383-94.
    View in: PubMed
    Score: 0.001
  105. Marrack P, Kappler J, Kotzin BL. Autoimmune disease: why and where it occurs. Nat Med. 2001 Aug; 7(8):899-905.
    View in: PubMed
    Score: 0.001
  106. Meyer AL, Trollmo C, Crawford F, Marrack P, Steere AC, Huber BT, Kappler J, Hafler DA. Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers. Proc Natl Acad Sci U S A. 2000 Oct 10; 97(21):11433-8.
    View in: PubMed
    Score: 0.001
  107. White J, Kappler J, Marrack P. Production and characterization of T cell hybridomas. Methods Mol Biol. 2000; 134:185-93.
    View in: PubMed
    Score: 0.001
  108. Ku CC, Kotzin B, Kappler J, Marrack P. CD8+ T-cell clones in old mice. Immunol Rev. 1997 Dec; 160:139-44.
    View in: PubMed
    Score: 0.001
  109. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T-cell/B-cell cooperation. VI. Distinct patterns of cross-reactivity by two human gamma-globulin-primed helper T-cell subpopulations. Cell Immunol. 1977 Sep; 33(1):20-32.
    View in: PubMed
    Score: 0.001
  110. Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
    View in: PubMed
    Score: 0.001
  111. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. IV. Development of a model system demonstrating responsiveness of two T cell functions to HGG in vitro. J Immunol. 1976 Nov; 117(5 Pt.2):1953-9.
    View in: PubMed
    Score: 0.001
  112. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. V. Unresponsiveness to HGG in vitro of these two T cell subpopulations. J Immunol. 1976 Nov; 117(5 Pt.2):1960-5.
    View in: PubMed
    Score: 0.001
  113. Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med. 1996 Nov 01; 184(5):1619-30.
    View in: PubMed
    Score: 0.001
  114. Donahue JP, Ricalton NS, Behrendt CE, Rittershaus C, Calaman S, Marrack P, Kappler JW, Kotzin BL. Genetic analysis of low V beta 3 expression in humans. J Exp Med. 1994 May 01; 179(5):1701-6.
    View in: PubMed
    Score: 0.001
  115. Penzien JM, Kappler J, Herschkowitz N, Schuknecht B, Leinekugel P, Propping P, T?nnesen T, Lou H, Moser H, Zierz S, et al. Compound heterozygosity for metachromatic leukodystrophy and arylsulfatase A pseudodeficiency alleles is not associated with progressive neurological disease. Am J Hum Genet. 1993 Mar; 52(3):557-64.
    View in: PubMed
    Score: 0.001
  116. Kotzin BL, Leung DY, Kappler J, Marrack P. Superantigens and their potential role in human disease. Adv Immunol. 1993; 54:99-166.
    View in: PubMed
    Score: 0.001
  117. Herman A, Labrecque N, Thibodeau J, Marrack P, Kappler JW, Sekaly RP. Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR. Proc Natl Acad Sci U S A. 1991 Nov 15; 88(22):9954-8.
    View in: PubMed
    Score: 0.001
  118. Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8357-61.
    View in: PubMed
    Score: 0.001
  119. Paliard X, West SG, Lafferty JA, Clements JR, Kappler JW, Marrack P, Kotzin BL. Evidence for the effects of a superantigen in rheumatoid arthritis. Science. 1991 Jul 19; 253(5017):325-9.
    View in: PubMed
    Score: 0.001
  120. Herman A, Kappler JW, Marrack P, Pullen AM. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol. 1991; 9:745-72.
    View in: PubMed
    Score: 0.001
  121. Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med. 1990 Sep 01; 172(3):709-17.
    View in: PubMed
    Score: 0.001
  122. Choi Y, Lafferty JA, Clements JR, Todd JK, Gelfand EW, Kappler J, Marrack P, Kotzin BL. Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med. 1990 Sep 01; 172(3):981-4.
    View in: PubMed
    Score: 0.001
  123. Born W, Miles C, White J, O'Brien R, Freed JH, Marrack P, Kappler J, Kubo RT. Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins. Nature. 1987 Dec 10-16; 330(6148):572-4.
    View in: PubMed
    Score: 0.000
  124. Gay D, Kappler J, Marrack P. L3T4 interacts with class II molecules on target cells. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):127-31.
    View in: PubMed
    Score: 0.000
  125. Blackman M, Yag?e J, Kubo R, Gay D, Coleclough C, Palmer E, Kappler J, Marrack P. The T cell repertoire may be biased in favor of MHC recognition. Cell. 1986 Nov 07; 47(3):349-57.
    View in: PubMed
    Score: 0.000
  126. Zlotnik A, Shimonkevitz R, Kappler J, Marrack P. Effect of prostaglandin E2 on the gamma-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas. Cell Immunol. 1985 Jan; 90(1):154-66.
    View in: PubMed
    Score: 0.000
  127. Hannum CH, Kappler JW, Trowbridge IS, Marrack P, Freed JH. Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor. Nature. 1984 Nov 1-7; 312(5989):65-7.
    View in: PubMed
    Score: 0.000
  128. Oettgen HC, Kappler J, Tax WJ, Terhorst C. Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. J Biol Chem. 1984 Oct 10; 259(19):12039-48.
    View in: PubMed
    Score: 0.000
  129. Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunol Rev. 1984 Oct; 81:161-76.
    View in: PubMed
    Score: 0.000
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)