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Connection

James DeGregori to Neoplasms

This is a "connection" page, showing publications James DeGregori has written about Neoplasms.

 
Connection Strength
 
 
 
4.721
 
  1. De Dominici M, DeGregori J. Of Barriers and Loops-How Evolution Limits Most Cancer Risks to Older Ages. Cancer Discov. 2026 Jan 12; 16(1):16-34.
    View in: PubMed
    Score: 0.315
  2. Henry CJ, DeGregori J. Modelling the ageing dependence of cancer evolutionary trajectories. Nat Rev Cancer. 2025 Oct; 25(10):757-780.
    View in: PubMed
    Score: 0.304
  3. DeGregori J, Seidl KJ, Montano M. Aging and Cancer-Inextricably Linked Across the Lifespan. Aging Cell. 2025 04; 24(4):e14483.
    View in: PubMed
    Score: 0.294
  4. Pietras EM, DeGregori J. Dangerous Liaisons between Tet2 Mutation, Inflammatory Monocytes, and Leukemogenesis. Cancer Discov. 2022 10 05; 12(10):2234-2236.
    View in: PubMed
    Score: 0.251
  5. Marongiu F, DeGregori J. The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease. Mol Oncol. 2022 09; 16(18):3238-3258.
    View in: PubMed
    Score: 0.246
  6. Chia SB, DeGregori J. Cancer stem cells in the gut have a bad influence on neighbouring cells. Nature. 2021 06; 594(7863):340-341.
    View in: PubMed
    Score: 0.229
  7. De Dominici M, DeGregori J. Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin. Cancer Discov. 2021 02; 11(2):227-229.
    View in: PubMed
    Score: 0.223
  8. DeGregori J, Pharoah P, Sasieni P, Swanton C. Cancer Screening, Surrogates of Survival, and the Soma. Cancer Cell. 2020 10 12; 38(4):433-437.
    View in: PubMed
    Score: 0.218
  9. Pham-Danis C, DeGregori J. Studying Cancer Evolution and Therapeutic Responses in Different Organs: The Pros and Cons of a Broad Focus. Cancer Res. 2019 Sep 15; 79(18):4582-4584.
    View in: PubMed
    Score: 0.202
  10. Higa KC, DeGregori J. Decoy fitness peaks, tumor suppression, and aging. Aging Cell. 2019 06; 18(3):e12938.
    View in: PubMed
    Score: 0.196
  11. DeGregori J. Connecting Cancer to Its Causes Requires Incorporation of Effects on Tissue Microenvironments. Cancer Res. 2017 11 15; 77(22):6065-6068.
    View in: PubMed
    Score: 0.175
  12. Liggett LA, DeGregori J. Changing mutational and adaptive landscapes and the genesis of cancer. Biochim Biophys Acta Rev Cancer. 2017 Apr; 1867(2):84-94.
    View in: PubMed
    Score: 0.169
  13. Rozhok AI, DeGregori J. Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):8914-21.
    View in: PubMed
    Score: 0.152
  14. Rozhok AI, Wahl GM, DeGregori J. A Critical Examination of the "Bad Luck" Explanation of Cancer Risk. Cancer Prev Res (Phila). 2015 Sep; 8(9):762-4.
    View in: PubMed
    Score: 0.152
  15. Alvarez-Calderon F, DeGregori J. Oncogenic drivers and mitochondrial dependency. Aging (Albany NY). 2015 Mar; 7(3):148-9.
    View in: PubMed
    Score: 0.148
  16. Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. Aging (Albany NY). 2014 Dec; 6(12):1033-48.
    View in: PubMed
    Score: 0.146
  17. DeGregori J. Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age? Oncogene. 2013 Apr 11; 32(15):1869-75.
    View in: PubMed
    Score: 0.123
  18. DeGregori J. Evolved tumor suppression: why are we so good at not getting cancer? Cancer Res. 2011 Jun 01; 71(11):3739-44.
    View in: PubMed
    Score: 0.114
  19. Marusyk A, DeGregori J. Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochim Biophys Acta. 2008 Jan; 1785(1):1-11.
    View in: PubMed
    Score: 0.089
  20. DeGregori J. Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesis. Mol Cell Biol. 2006 Feb; 26(4):1165-9.
    View in: PubMed
    Score: 0.079
  21. Vincze O, Spada B, Bilder D, Cagan A, DeGregori J, Gorbunova V, Maley CC, Schiffman JD, Seluanov A, Giraudeau M, Pradeu T. Advancing cancer research via comparative oncology. Nat Rev Cancer. 2025 Sep; 25(9):740-748.
    View in: PubMed
    Score: 0.076
  22. Giraudeau M, Vincze O, Dupont SM, Sepp T, Baines C, Lemaitre JF, Lemberger K, Gentès S, Boddy A, Dujon AM, Bramwell G, Harris V, Ujvari B, Alix-Panabières C, Lair S, Sayag D, Conde DA, Colchero F, Harrison TM, Pavard S, Padilla-Morales B, Chevallier D, Hamede R, Roche B, Malkocs T, Aktipis AC, Maley C, DeGregori J, Le Loc'h G, Thomas F. Approaches and methods to study wildlife cancer. J Anim Ecol. 2024 10; 93(10):1410-1428.
    View in: PubMed
    Score: 0.072
  23. Bramwell G, DeGregori J, Thomas F, Ujvari B. Transmissible cancers, the genomes that do not melt down. Evolution. 2024 Jul 01; 78(7):1205-1211.
    View in: PubMed
    Score: 0.071
  24. Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, Quezada S, Wargo JA, Weeraratna A, White E, Winkler F, Wood JN, Vousden KH, Hanahan D. Embracing cancer complexity: Hallmarks of systemic disease. Cell. 2024 Mar 28; 187(7):1589-1616.
    View in: PubMed
    Score: 0.070
  25. Somarelli JA, DeGregori J, Gerlinger M, Heng HH, Marusyk A, Welch DR, Laukien FH. Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes. Med Oncol. 2022 Jul 04; 39(9):137.
    View in: PubMed
    Score: 0.062
  26. DeGregori J. The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim Biophys Acta. 2002 Jun 21; 1602(2):131-50.
    View in: PubMed
    Score: 0.061
  27. Zhu JW, Field SJ, Gore L, Thompson M, Yang H, Fujiwara Y, Cardiff RD, Greenberg M, Orkin SH, DeGregori J. E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis. Mol Cell Biol. 2001 Dec; 21(24):8547-64.
    View in: PubMed
    Score: 0.059
  28. Capp JP, DeGregori J, Nedelcu AM, Dujon AM, Boutry J, Pujol P, Alix-Panabières C, Hamede R, Roche B, Ujvari B, Marusyk A, Gatenby R, Thomas F. Group phenotypic composition in cancer. Elife. 2021 03 30; 10.
    View in: PubMed
    Score: 0.056
  29. Laconi E, Marongiu F, DeGregori J. Cancer as a disease of old age: changing mutational and microenvironmental landscapes. Br J Cancer. 2020 03; 122(7):943-952.
    View in: PubMed
    Score: 0.052
  30. Somarelli JA, Gardner H, Cannataro VL, Gunady EF, Boddy AM, Johnson NA, Fisk JN, Gaffney SG, Chuang JH, Li S, Ciccarelli FD, Panchenko AR, Megquier K, Kumar S, Dornburg A, DeGregori J, Townsend JP. Molecular Biology and Evolution of Cancer: From Discovery to Action. Mol Biol Evol. 2020 02 01; 37(2):320-326.
    View in: PubMed
    Score: 0.052
  31. Guida JL, Ahles TA, Belsky D, Campisi J, Cohen HJ, DeGregori J, Fuldner R, Ferrucci L, Gallicchio L, Gavrilov L, Gavrilova N, Green PA, Jhappan C, Kohanski R, Krull K, Mandelblatt J, Ness KK, O'Mara A, Price N, Schrack J, Studenski S, Theou O, Tracy RP, Hurria A. Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors. J Natl Cancer Inst. 2019 12 01; 111(12):1245-1254.
    View in: PubMed
    Score: 0.052
  32. Rozhok A, DeGregori J. Somatic maintenance impacts the evolution of mutation rate. BMC Evol Biol. 2019 08 23; 19(1):172.
    View in: PubMed
    Score: 0.051
  33. Rozhok A, DeGregori J. A generalized theory of age-dependent carcinogenesis. Elife. 2019 04 29; 8.
    View in: PubMed
    Score: 0.049
  34. Rozhok AI, DeGregori J. The evolution of lifespan and age-dependent cancer risk. Trends Cancer. 2016 10; 2(10):552-560.
    View in: PubMed
    Score: 0.041
  35. Yadav VK, DeGregori J, De S. The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection. Nucleic Acids Res. 2016 Mar 18; 44(5):2075-84.
    View in: PubMed
    Score: 0.040
  36. Gore L, DeGregori J, Porter CC. Targeting developmental pathways in children with cancer: what price success? Lancet Oncol. 2013 Feb; 14(2):e70-8.
    View in: PubMed
    Score: 0.032
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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