Connection
Douglas Seals to Aged
This is a "connection" page, showing publications Douglas Seals has written about Aged.
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2.986 |
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Moreau KL, Clayton ZS, DuBose LE, Rosenberry R, Seals DR. Effects of regular exercise on vascular function with aging: Does sex matter? Am J Physiol Heart Circ Physiol. 2024 01 01; 326(1):H123-H137.
Score: 0.063
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Craighead DH, Freeberg KA, Heinbockel TC, Rossman MJ, Jackman RA, McCarty NP, Jankowski LR, Nemkov T, Reisz JA, D'Alessandro A, Chonchol M, Bailey EF, Seals DR. Time-Efficient, High-Resistance Inspiratory Muscle Strength Training Increases Exercise Tolerance in Midlife and Older Adults. Med Sci Sports Exerc. 2024 Feb 01; 56(2):266-276.
Score: 0.062
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Freeberg KA, Craighead DH, Heinbockel TC, Rossman MJ, Jackman RA, Jankowski LR, Ludwig KR, Chonchol M, Bailey EF, Seals DR. Time-efficient, high-resistance inspiratory muscle strength training increases cerebrovascular reactivity in midlife and older adults. Am J Physiol Heart Circ Physiol. 2023 11 01; 325(5):H1059-H1068.
Score: 0.062
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Brunt VE, Ikoba AP, Ziemba BP, Ballak DB, Hoischen A, Dinarello CA, Ehringer MA, Seals DR. Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs. Geroscience. 2023 02; 45(1):65-84.
Score: 0.057
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Craighead DH, Freeberg KA, McCarty NP, Seals DR. Time-efficient, high-resistance inspiratory muscle strength training for cardiovascular aging. Exp Gerontol. 2021 10 15; 154:111515.
Score: 0.054
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Craighead DH, Heinbockel TC, Freeberg KA, Rossman MJ, Jackman RA, Jankowski LR, Hamilton MN, Ziemba BP, Reisz JA, D'Alessandro A, Brewster LM, DeSouza CA, You Z, Chonchol M, Bailey EF, Seals DR. Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure. J Am Heart Assoc. 2021 07 06; 10(13):e020980.
Score: 0.054
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Brunt VE, Casso AG, Gioscia-Ryan RA, Sapinsley ZJ, Ziemba BP, Clayton ZS, Bazzoni AE, VanDongen NS, Richey JJ, Hutton DA, Zigler MC, Neilson AP, Davy KP, Seals DR. Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans. Hypertension. 2021 08; 78(2):499-511.
Score: 0.053
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Rossman MJ, Gioscia-Ryan RA, Santos-Parker JR, Ziemba BP, Lubieniecki KL, Johnson LC, Poliektov NE, Bispham NZ, Woodward KA, Nagy EE, Bryan NS, Reisz JA, D'Alessandro A, Chonchol M, Sindler AL, Seals DR. Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress. Hypertension. 2021 04; 77(4):1212-1222.
Score: 0.052
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Craighead DH, Freeberg KA, Seals DR. Vascular Endothelial Function in Midlife/Older Adults Classified According to 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines. J Am Heart Assoc. 2020 09; 9(17):e016625.
Score: 0.050
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Brunt VE, Gioscia-Ryan RA, Casso AG, VanDongen NS, Ziemba BP, Sapinsley ZJ, Richey JJ, Zigler MC, Neilson AP, Davy KP, Seals DR. Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans. Hypertension. 2020 07; 76(1):101-112.
Score: 0.050
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Martens CR, Rossman MJ, Mazzo MR, Jankowski LR, Nagy EE, Denman BA, Richey JJ, Johnson SA, Ziemba BP, Wang Y, Peterson CM, Chonchol M, Seals DR. Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults. Geroscience. 2020 04; 42(2):667-686.
Score: 0.048
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Craighead DH, Heinbockel TC, Hamilton MN, Bailey EF, MacDonald MJ, Gibala MJ, Seals DR. Time-efficient physical training for enhancing cardiovascular function in midlife and older adults: promise and current research gaps. J Appl Physiol (1985). 2019 11 01; 127(5):1427-1440.
Score: 0.047
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Santos-Parker JR, Santos-Parker KS, McQueen MB, Martens CR, Seals DR. Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan. J Appl Physiol (1985). 2018 11 01; 125(5):1646-1659.
Score: 0.044
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Rossman MJ, Santos-Parker JR, Steward CAC, Bispham NZ, Cuevas LM, Rosenberg HL, Woodward KA, Chonchol M, Gioscia-Ryan RA, Murphy MP, Seals DR. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension. 2018 06; 71(6):1056-1063.
Score: 0.043
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Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR. Chronic?nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018 03 29; 9(1):1286.
Score: 0.043
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Nowak KL, Rossman MJ, Chonchol M, Seals DR. Strategies for Achieving Healthy Vascular Aging. Hypertension. 2018 03; 71(3):389-402.
Score: 0.042
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Tanaka H, Dinenno FA, Seals DR. Reductions in central arterial compliance with age are related to sympathetic vasoconstrictor nerve activity in healthy men. Hypertens Res. 2017 May; 40(5):493-495.
Score: 0.039
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Santos-Parker JR, Strahler TR, Bassett CJ, Bispham NZ, Chonchol MB, Seals DR. Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress. Aging (Albany NY). 2017 01 03; 9(1):187-208.
Score: 0.039
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Kaplon RE, Hill SD, Bispham NZ, Santos-Parker JR, Nowlan MJ, Snyder LL, Chonchol M, LaRocca TJ, McQueen MB, Seals DR. Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults. Aging (Albany NY). 2016 06; 8(6):1167-83.
Score: 0.038
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DeVan AE, Johnson LC, Brooks FA, Evans TD, Justice JN, Cruickshank-Quinn C, Reisdorph N, Bryan NS, McQueen MB, Santos-Parker JR, Chonchol MB, Bassett CJ, Sindler AL, Giordano T, Seals DR. Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults. J Appl Physiol (1985). 2016 Feb 15; 120(4):416-25.
Score: 0.036
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Justice JN, Johnson LC, DeVan AE, Cruickshank-Quinn C, Reisdorph N, Bassett CJ, Evans TD, Brooks FA, Bryan NS, Chonchol MB, Giordano T, McQueen MB, Seals DR. Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults. Aging (Albany NY). 2015 Nov; 7(11):1004-21.
Score: 0.036
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Jablonski KL, Klawitter J, Chonchol M, Bassett CJ, Racine ML, Seals DR. Effect of dietary sodium restriction on human urinary metabolomic profiles. Clin J Am Soc Nephrol. 2015 Jul 07; 10(7):1227-34.
Score: 0.035
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Seals DR, Justice JN, LaRocca TJ. Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity. J Physiol. 2016 Apr 15; 594(8):2001-24.
Score: 0.035
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Walker AE, Kaplon RE, Pierce GL, Nowlan MJ, Seals DR. Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor ?B. Clin Sci (Lond). 2014 Dec; 127(11):645-54.
Score: 0.034
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Kaplon RE, Gano LB, Seals DR. Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults. J Appl Physiol (1985). 2014 Jan 15; 116(2):156-63.
Score: 0.032
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Moreau KL, Stauffer BL, Kohrt WM, Seals DR. Essential role of estrogen for improvements in vascular endothelial function with endurance exercise in postmenopausal women. J Clin Endocrinol Metab. 2013 Nov; 98(11):4507-15.
Score: 0.031
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Jablonski KL, Fedorova OV, Racine ML, Geolfos CJ, Gates PE, Chonchol M, Fleenor BS, Lakatta EG, Bagrov AY, Seals DR. Dietary sodium restriction and association with urinary marinobufagenin, blood pressure, and aortic stiffness. Clin J Am Soc Nephrol. 2013 Nov; 8(11):1952-9.
Score: 0.031
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Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD, Henson GD, Lawson BR, Lesniewski LA, Seals DR. Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell. 2013 Oct; 12(5):772-83.
Score: 0.031
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DeVan AE, Eskurza I, Pierce GL, Walker AE, Jablonski KL, Kaplon RE, Seals DR. Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. Clin Sci (Lond). 2013 Mar; 124(5):325-31.
Score: 0.030
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Jablonski KL, Racine ML, Geolfos CJ, Gates PE, Chonchol M, McQueen MB, Seals DR. Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure. J Am Coll Cardiol. 2013 Jan 22; 61(3):335-43.
Score: 0.029
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Walker AE, Kaplon RE, Lucking SM, Russell-Nowlan MJ, Eckel RH, Seals DR. Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults. Hypertension. 2012 Dec; 60(6):1517-23.
Score: 0.029
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Christou DD, Pierce GL, Walker AE, Hwang MH, Yoo JK, Luttrell M, Meade TH, English M, Seals DR. Vascular smooth muscle responsiveness to nitric oxide is reduced in healthy adults with increased adiposity. Am J Physiol Heart Circ Physiol. 2012 Sep 15; 303(6):H743-50.
Score: 0.029
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Pierce GL, Jablonski KL, Walker AE, Seibert SM, DeVan AE, Black SM, Sharma S, Seals DR. Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study. Am J Hypertens. 2012 Oct; 25(10):1050-4.
Score: 0.029
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LaRocca TJ, Henson GD, Thorburn A, Sindler AL, Pierce GL, Seals DR. Translational evidence that impaired autophagy contributes to arterial ageing. J Physiol. 2012 Jul 15; 590(14):3305-16.
Score: 0.028
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Jalal DI, Jablonski KL, McFann K, Chonchol MB, Seals DR. Vascular endothelial function is not related to serum uric acid in healthy adults. Am J Hypertens. 2012 Apr; 25(4):407-13.
Score: 0.028
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Fleenor BS, Marshall KD, Rippe C, Seals DR. Replicative aging induces endothelial to mesenchymal transition in human aortic endothelial cells: potential role of inflammation. J Vasc Res. 2012; 49(1):59-64.
Score: 0.027
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Donato AJ, Magerko KA, Lawson BR, Durrant JR, Lesniewski LA, Seals DR. SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans. J Physiol. 2011 Sep 15; 589(Pt 18):4545-54.
Score: 0.027
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Gano LB, Donato AJ, Pierce GL, Pasha HM, Magerko KA, Roeca C, Seals DR. Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise. Physiol Genomics. 2011 Jul 27; 43(14):895-902.
Score: 0.027
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Pierce GL, Eskurza I, Walker AE, Fay TN, Seals DR. Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clin Sci (Lond). 2011 Jan; 120(1):13-23.
Score: 0.026
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Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR. 25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension. 2011 Jan; 57(1):63-9.
Score: 0.026
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Walker AE, Seibert SM, Donato AJ, Pierce GL, Seals DR. Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults. Hypertension. 2010 Feb; 55(2):363-9.
Score: 0.024
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Jablonski KL, Gates PE, Pierce GL, Seals DR. Low dietary sodium intake is associated with enhanced vascular endothelial function in middle-aged and older adults with elevated systolic blood pressure. Ther Adv Cardiovasc Dis. 2009 Oct; 3(5):347-56.
Score: 0.024
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Donato AJ, Pierce GL, Lesniewski LA, Seals DR. Role of NFkappaB in age-related vascular endothelial dysfunction in humans. Aging (Albany NY). 2009 Aug 10; 1(8):678-80.
Score: 0.023
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Silver AE, Christou DD, Donato AJ, Beske SD, Moreau KL, Magerko KA, Seals DR. Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins. J Vasc Res. 2010; 47(1):1-8.
Score: 0.023
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Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K, Seals DR. Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H425-32.
Score: 0.023
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Pierce GL, Lesniewski LA, Lawson BR, Beske SD, Seals DR. Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation. 2009 Mar 10; 119(9):1284-92.
Score: 0.023
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Walker AE, Eskurza I, Pierce GL, Gates PE, Seals DR. Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise. Am J Hypertens. 2009 Mar; 22(3):250-6.
Score: 0.022
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Donato AJ, Black AD, Jablonski KL, Gano LB, Seals DR. Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell. 2008 Dec; 7(6):805-12.
Score: 0.022
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Donato AJ, Eskurza I, Jablonski KL, Gano LB, Pierce GL, Seals DR. Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. J Appl Physiol (1985). 2008 Oct; 105(4):1359-63.
Score: 0.022
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Pierce GL, Beske SD, Lawson BR, Southall KL, Benay FJ, Donato AJ, Seals DR. Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults. Hypertension. 2008 Jul; 52(1):72-9.
Score: 0.022
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Christou DD, Seals DR. Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate. J Appl Physiol (1985). 2008 Jul; 105(1):24-9.
Score: 0.022
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Donato AJ, Eskurza I, Silver AE, Levy AS, Pierce GL, Gates PE, Seals DR. Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB. Circ Res. 2007 Jun 08; 100(11):1659-66.
Score: 0.020
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Stob NR, Bell C, van Baak MA, Seals DR. Thermic effect of food and beta-adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans. J Appl Physiol (1985). 2007 Aug; 103(2):616-22.
Score: 0.020
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Silver AE, Beske SD, Christou DD, Donato AJ, Moreau KL, Eskurza I, Gates PE, Seals DR. Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress. Circulation. 2007 Feb 06; 115(5):627-37.
Score: 0.020
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Moreau KL, Silver AE, Dinenno FA, Seals DR. Habitual aerobic exercise is associated with smaller femoral artery intima-media thickness with age in healthy men and women. Eur J Cardiovasc Prev Rehabil. 2006 Oct; 13(5):805-11.
Score: 0.019
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Gates PE, Seals DR. Decline in large elastic artery compliance with age: a therapeutic target for habitual exercise. Br J Sports Med. 2006 Nov; 40(11):897-9.
Score: 0.019
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Gates PE, Boucher ML, Silver AE, Monahan KD, Seals DR. Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression. J Appl Physiol (1985). 2007 Jan; 102(1):63-71.
Score: 0.019
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Eskurza I, Kahn ZD, Seals DR. Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing. J Physiol. 2006 Mar 15; 571(Pt 3):661-8.
Score: 0.018
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Bell C, Stob NR, Seals DR. Thermogenic responsiveness to beta-adrenergic stimulation is augmented in exercising versus sedentary adults: role of oxidative stress. J Physiol. 2006 Feb 01; 570(Pt 3):629-35.
Score: 0.018
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Bell C, Stob NR, Seals DR. Thermogenic responsiveness to nonspecific beta-adrenergic stimulation is not related to genetic variation in codon 16 of the beta2-adrenergic receptor. Am J Physiol Endocrinol Metab. 2006 Apr; 290(4):E703-7.
Score: 0.018
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Eskurza I, Myerburgh LA, Kahn ZD, Seals DR. Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol. 2005 Nov 01; 568(Pt 3):1057-65.
Score: 0.018
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Bell C, Carson JM, Motte NW, Seals DR. Ascorbic acid does not affect the age-associated reduction in maximal cardiac output and oxygen consumption in healthy adults. J Appl Physiol (1985). 2005 Mar; 98(3):845-9.
Score: 0.017
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Jones PP, Van Pelt RE, Johnson DG, Seals DR. Role of sympathetic neural activation in age- and habitual exercise-related differences in the thermic effect of food. J Clin Endocrinol Metab. 2004 Oct; 89(10):5138-44.
Score: 0.017
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Bell C, Day DS, Jones PP, Christou DD, Petitt DS, Osterberg K, Melby CL, Seals DR. High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults. J Clin Endocrinol Metab. 2004 Jul; 89(7):3573-8.
Score: 0.016
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Christou DD, Jones PP, Pimentel AE, Seals DR. Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging. Am J Physiol Heart Circ Physiol. 2004 Oct; 287(4):H1530-7.
Score: 0.016
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Gates PE, Tanaka H, Hiatt WR, Seals DR. Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension. 2004 Jul; 44(1):35-41.
Score: 0.016
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Eskurza I, Monahan KD, Robinson JA, Seals DR. Ascorbic acid does not affect large elastic artery compliance or central blood pressure in young and older men. Am J Physiol Heart Circ Physiol. 2004 Apr; 286(4):H1528-34.
Score: 0.016
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Monahan KD, Eskurza I, Seals DR. Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am J Physiol Heart Circ Physiol. 2004 Jun; 286(6):H2113-7.
Score: 0.016
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Seals DR, Bell C. Chronic sympathetic activation: consequence and cause of age-associated obesity? Diabetes. 2004 Feb; 53(2):276-84.
Score: 0.016
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Eskurza I, Monahan KD, Robinson JA, Seals DR. Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol. 2004 Apr 01; 556(Pt 1):315-24.
Score: 0.016
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Gates PE, Tanaka H, Graves J, Seals DR. Left ventricular structure and diastolic function with human ageing. Relation to habitual exercise and arterial stiffness. Eur Heart J. 2003 Dec; 24(24):2213-20.
Score: 0.016
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Freeberg KA, Udovich CC, Martens CR, Seals DR, Craighead DH. Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions. J Gerontol A Biol Sci Med Sci. 2023 12 01; 78(12):2435-2448.
Score: 0.016
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Bhasin S, Seals D, Migaud M, Musi N, Baur JA. Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns. Endocr Rev. 2023 11 09; 44(6):1047-1073.
Score: 0.016
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Tanaka H, Seals DR. Invited Review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity. J Appl Physiol (1985). 2003 Nov; 95(5):2152-62.
Score: 0.016
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Bell C, Petitt DS, Jones PP, Seals DR. Influence of adiposity on tonic sympathetic support of resting metabolism in healthy adults. Int J Obes Relat Metab Disord. 2003 Nov; 27(11):1315-8.
Score: 0.016
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Bell C, Jones PP, Seals DR. Oxidative stress does not modulate metabolic rate or skeletal muscle sympathetic activity with primary aging in adult humans. J Clin Endocrinol Metab. 2003 Oct; 88(10):4950-4.
Score: 0.016
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Freeberg KA, Ludwig KR, Chonchol M, Seals DR, Rossman MJ. NAD+-boosting compounds enhance nitric oxide production and prevent oxidative stress in endothelial cells exposed to plasma from patients with COVID-19. Nitric Oxide. 2023 Nov 01; 140-141:1-7.
Score: 0.016
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Murray KO, Ludwig KR, Darvish S, Coppock ME, Seals DR, Rossman MJ. Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol. 2023 07 01; 325(1):H187-H194.
Score: 0.015
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Jones PP, Christou DD, Jordan J, Seals DR. Baroreflex buffering is reduced with age in healthy men. Circulation. 2003 Apr 08; 107(13):1770-4.
Score: 0.015
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Oh ES, Freeberg KA, Steele CN, Wang W, Farmer-Bailey H, Coppock ME, Seals DR, Chonchol M, Rossman MJ, Craighead DH, Nowak KL. Cerebrovascular pulsatility index is higher in chronic kidney disease. Physiol Rep. 2023 01; 11(1):e15561.
Score: 0.015
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Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin. Aging Cell. 2023 01; 22(1):e13754.
Score: 0.015
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Craighead DH, Tavoian D, Freeberg KA, Mazzone JL, Vranish JR, DeLucia CM, Seals DR, Bailey EF. A multi-trial, retrospective analysis of the antihypertensive effects of high-resistance, low-volume inspiratory muscle strength training. J Appl Physiol (1985). 2022 10 01; 133(4):1001-1010.
Score: 0.015
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Shannon OM, Clifford T, Seals DR, Craighead DH, Rossman MJ. Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes. Nitric Oxide. 2022 08 01; 125-126:31-39.
Score: 0.014
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Esler M, Lambert G, Kaye D, Rumantir M, Hastings J, Seals DR. Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress. Biogerontology. 2002; 3(1-2):45-9.
Score: 0.014
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Jones PP, Shapiro LF, Keisling GA, Jordan J, Shannon JR, Quaife RA, Seals DR. Altered autonomic support of arterial blood pressure with age in healthy men. Circulation. 2001 Nov 13; 104(20):2424-9.
Score: 0.014
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Dinenno FA, Tanaka H, Monahan KD, Clevenger CM, Eskurza I, DeSouza CA, Seals DR. Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men. J Physiol. 2001 Jul 01; 534(Pt 1):287-95.
Score: 0.013
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Wahl D, Cavalier AN, Smith M, Seals DR, LaRocca TJ. Healthy Aging Interventions Reduce Repetitive Element Transcripts. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):805-810.
Score: 0.013
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Casas YG, Schiller BC, DeSouza CA, Seals DR. Total and regional body composition across age in healthy Hispanic and white women of similar socioeconomic status. Am J Clin Nutr. 2001 Jan; 73(1):13-8.
Score: 0.013
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Tanaka H, Dinenno FA, Monahan KD, DeSouza CA, Seals DR. Carotid artery wall hypertrophy with age is related to local systolic blood pressure in healthy men. Arterioscler Thromb Vasc Biol. 2001 Jan; 21(1):82-7.
Score: 0.013
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Tanaka H, Monahan KD, Seals DR. Age-predicted maximal heart rate revisited. J Am Coll Cardiol. 2001 Jan; 37(1):153-6.
Score: 0.013
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Wagner J, Knaier R, Infanger D, K?nigstein K, Klenk C, Carrard J, Hanssen H, Hinrichs T, Seals D, Schmidt-Trucks?ss A. Novel CPET Reference Values in Healthy Adults: Associations with Physical Activity. Med Sci Sports Exerc. 2021 01; 53(1):26-37.
Score: 0.013
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Schiller BC, Casas YG, Tracy BL, DeSouza CA, Seals DR. Age-related declines in knee extensor strength and physical performance in healthy Hispanic and Caucasian women. J Gerontol A Biol Sci Med Sci. 2000 Dec; 55(12):B563-9.
Score: 0.013
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Monahan KD, Dinenno FA, Tanaka H, Clevenger CM, DeSouza CA, Seals DR. Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men. J Physiol. 2000 Nov 15; 529 Pt 1:263-71.
Score: 0.013
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DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, Seals DR. Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation. 2000 Sep 19; 102(12):1351-7.
Score: 0.013
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Tanaka H, Dinenno FA, Monahan KD, Clevenger CM, DeSouza CA, Seals DR. Aging, habitual exercise, and dynamic arterial compliance. Circulation. 2000 Sep 12; 102(11):1270-5.
Score: 0.013
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Wang W, Chonchol M, Seals DR, Nowak KL. Dietary sodium restriction decreases urinary NGAL in older adults with moderately elevated systolic blood pressure free from chronic kidney disease. J Investig Med. 2020 10; 68(7):1271-1275.
Score: 0.013
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Ozemek C, Hildreth KL, Blatchford PJ, Hurt KJ, Bok R, Seals DR, Kohrt WM, Moreau KL. Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women. J Appl Physiol (1985). 2020 04 01; 128(4):739-747.
Score: 0.012
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Johnson LC, Parker K, Aguirre BF, Nemkov TG, D'Alessandro A, Johnson SA, Seals DR, Martens CR. The plasma metabolome as a predictor of biological aging in humans. Geroscience. 2019 12; 41(6):895-906.
Score: 0.012
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Tanaka H, Davy KP, Seals DR. Cardiopulmonary baroreflex inhibition of sympathetic nerve activity is preserved with age in healthy humans. J Physiol. 1999 Feb 15; 515 ( Pt 1):249-54.
Score: 0.011
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Davy KP, Tanaka H, Andros EA, Gerber JG, Seals DR. Influence of age on arterial baroreflex inhibition of sympathetic nerve activity in healthy adult humans. Am J Physiol. 1998 11; 275(5):H1768-72.
Score: 0.011
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Tanaka H, Dinenno FA, Hunt BE, Jones PP, DeSouza CA, Seals DR. Hemodynamic sequelae of age-related increases in arterial stiffness in healthy women. Am J Cardiol. 1998 Nov 01; 82(9):1152-5, A10.
Score: 0.011
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Van Pelt RE, Davy KP, Stevenson ET, Wilson TM, Jones PP, Desouza CA, Seals DR. Smaller differences in total and regional adiposity with age in women who regularly perform endurance exercise. Am J Physiol. 1998 10; 275(4):E626-34.
Score: 0.011
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Tanaka H, DeSouza CA, Seals DR. Arterial stiffness and hormone replacement use in healthy postmenopausal women. J Gerontol A Biol Sci Med Sci. 1998 Sep; 53(5):M344-6.
Score: 0.011
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Tanaka H, Reiling MJ, Seals DR. Regular walking increases peak limb vasodilatory capacity of older hypertensive humans: implications for arterial structure. J Hypertens. 1998 Apr; 16(4):423-8.
Score: 0.011
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Tanaka H, Desouza CA, Jones PP, Stevenson ET, Davy KP, Seals DR. Greater rate of decline in maximal aerobic capacity with age in physically active vs. sedentary healthy women. J Appl Physiol (1985). 1997 Dec; 83(6):1947-53.
Score: 0.010
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DeSouza CA, Dengel DR, Macko RF, Cox K, Seals DR. Elevated levels of circulating cell adhesion molecules in uncomplicated essential hypertension. Am J Hypertens. 1997 Dec; 10(12 Pt 1):1335-41.
Score: 0.010
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Hunt BE, Davy KP, Seals DR. Reproducibility of a semiautomated acetylene rebreathing technique for measuring cardiac output in humans at rest. Clin Physiol. 1997 Nov; 17(6):599-607.
Score: 0.010
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Van Pelt RE, Jones PP, Davy KP, Desouza CA, Tanaka H, Davy BM, Seals DR. Regular exercise and the age-related decline in resting metabolic rate in women. J Clin Endocrinol Metab. 1997 Oct; 82(10):3208-12.
Score: 0.010
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Rossman MJ, Kaplon RE, Hill SD, McNamara MN, Santos-Parker JR, Pierce GL, Seals DR, Donato AJ. Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function. Am J Physiol Heart Circ Physiol. 2017 Nov 01; 313(5):H890-H895.
Score: 0.010
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DeSouza CA, Stevenson ET, Davy KP, Jones PP, Seals DR. Plasma fibrinogen levels in healthy postmenopausal women: physical activity and hormone replacement status. J Gerontol A Biol Sci Med Sci. 1997 Sep; 52(5):M294-8.
Score: 0.010
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Kendrick J, Andrews E, You Z, Moreau K, Nowak KL, Farmer-Bailey H, Seals DR, Chonchol M. Cholecalciferol, Calcitriol, and Vascular Function in CKD: A Randomized, Double-Blind Trial. Clin J Am Soc Nephrol. 2017 Sep 07; 12(9):1438-1446.
Score: 0.010
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Fitzgerald MD, Tanaka H, Tran ZV, Seals DR. Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: a meta-analysis. J Appl Physiol (1985). 1997 Jul; 83(1):160-5.
Score: 0.010
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Tanaka H, Seals DR. Age and gender interactions in physiological functional capacity: insight from swimming performance. J Appl Physiol (1985). 1997 Mar; 82(3):846-51.
Score: 0.010
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Stevenson ET, Davy KP, Jones PP, Desouza CA, Seals DR. Blood pressure risks factors in healthy postmenopausal women: physical activity and hormone replacement. J Appl Physiol (1985). 1997 Feb; 82(2):652-60.
Score: 0.010
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Pierce GL, Harris SA, Seals DR, Casey DP, Barlow PB, Stauss HM. Estimated aortic stiffness is independently associated with cardiac baroreflex sensitivity in humans: role of ageing and habitual endurance exercise. J Hum Hypertens. 2016 09; 30(9):513-20.
Score: 0.009
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Taylor JA, Hayano J, Seals DR. Lesser vagal withdrawal during isometric exercise with age. J Appl Physiol (1985). 1995 Sep; 79(3):805-11.
Score: 0.009
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Justice JN, Cesari M, Seals DR, Shively CA, Carter CS. Comparative Approaches to Understanding the Relation Between Aging and Physical Function. J Gerontol A Biol Sci Med Sci. 2016 10; 71(10):1243-53.
Score: 0.009
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Davy KP, Johnson DG, Seals DR. Cardiovascular, plasma norepinephrine, and thermal adjustments to prolonged exercise in young and older healthy humans. Clin Physiol. 1995 Mar; 15(2):169-81.
Score: 0.009
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Ng AV, Johnson DG, Callister R, Seals DR. Muscle sympathetic nerve activity during postural change in healthy young and older adults. Clin Auton Res. 1995 Feb; 5(1):57-60.
Score: 0.009
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Esler M, Kaye D, Thompson J, Jennings G, Cox H, Turner A, Lambert G, Seals D. Effects of aging on epinephrine secretion and regional release of epinephrine from the human heart. J Clin Endocrinol Metab. 1995 Feb; 80(2):435-42.
Score: 0.009
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Esler MD, Thompson JM, Kaye DM, Turner AG, Jennings GL, Cox HS, Lambert GW, Seals DR. Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors. Circulation. 1995 Jan 15; 91(2):351-8.
Score: 0.009
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Esler MD, Turner AG, Kaye DM, Thompson JM, Kingwell BA, Morris M, Lambert GW, Jennings GL, Cox HS, Seals DR. Aging effects on human sympathetic neuronal function. Am J Physiol. 1995 Jan; 268(1 Pt 2):R278-85.
Score: 0.009
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Stevenson ET, Davy KP, Seals DR. Maximal aerobic capacity and total blood volume in highly trained middle-aged and older female endurance athletes. J Appl Physiol (1985). 1994 Oct; 77(4):1691-6.
Score: 0.008
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Ng AV, Callister R, Johnson DG, Seals DR. Endurance exercise training is associated with elevated basal sympathetic nerve activity in healthy older humans. J Appl Physiol (1985). 1994 Sep; 77(3):1366-74.
Score: 0.008
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Seals DR, Taylor JA, Ng AV, Esler MD. Exercise and aging: autonomic control of the circulation. Med Sci Sports Exerc. 1994 May; 26(5):568-76.
Score: 0.008
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Davy KP, Seals DR. Total blood volume in healthy young and older men. J Appl Physiol (1985). 1994 May; 76(5):2059-62.
Score: 0.008
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Kaplon RE, Chung E, Reese L, Cox-York K, Seals DR, Gentile CL. Activation of the unfolded protein response in vascular endothelial cells of nondiabetic obese adults. J Clin Endocrinol Metab. 2013 Sep; 98(9):E1505-9.
Score: 0.008
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Pierce GL, Casey DP, Fiedorowicz JG, Seals DR, Curry TB, Barnes JN, Wilson DR, Stauss HM. Aortic pulse wave velocity and reflecting distance estimation from peripheral waveforms in humans: detection of age- and exercise training-related differences. Am J Physiol Heart Circ Physiol. 2013 Jul 01; 305(1):H135-42.
Score: 0.008
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Ng AV, Callister R, Johnson DG, Seals DR. Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension. 1993 Apr; 21(4):498-503.
Score: 0.008
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Taylor JA, Hand GA, Johnson DG, Seals DR. Augmented forearm vasoconstriction during dynamic exercise in healthy older men. Circulation. 1992 Dec; 86(6):1789-99.
Score: 0.007
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Taylor JA, Hand GA, Johnson DG, Seals DR. Sympathoadrenal-circulatory regulation of arterial pressure during orthostatic stress in young and older men. Am J Physiol. 1992 Nov; 263(5 Pt 2):R1147-55.
Score: 0.007
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Gavin KM, Jankowski C, Kohrt WM, Stauffer BL, Seals DR, Moreau KL. Hysterectomy is associated with large artery stiffening in estrogen-deficient postmenopausal women. Menopause. 2012 Sep; 19(9):1000-7.
Score: 0.007
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Seals DR, Reiling MJ. Effect of regular exercise on 24-hour arterial pressure in older hypertensive humans. Hypertension. 1991 Nov; 18(5):583-92.
Score: 0.007
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Taylor JA, Hand GA, Johnson DG, Seals DR. Sympathoadrenal-circulatory regulation during sustained isometric exercise in young and older men. Am J Physiol. 1991 Nov; 261(5 Pt 2):R1061-9.
Score: 0.007
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LaRocca TJ, Seals DR, Pierce GL. Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity. Mech Ageing Dev. 2010 Feb; 131(2):165-7.
Score: 0.006
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Seals DR, Chase PB. Influence of physical training on heart rate variability and baroreflex circulatory control. J Appl Physiol (1985). 1989 Apr; 66(4):1886-95.
Score: 0.006
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Jablonski KL, Seals DR, Eskurza I, Monahan KD, Donato AJ. High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men. J Appl Physiol (1985). 2007 Nov; 103(5):1715-21.
Score: 0.005
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Mazzaro L, Almasi SJ, Shandas R, Seals DR, Gates PE. Aortic input impedance increases with age in healthy men and women. Hypertension. 2005 Jun; 45(6):1101-6.
Score: 0.004
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Christou DD, Gentile CL, DeSouza CA, Seals DR, Gates PE. Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men. Circulation. 2005 Apr 19; 111(15):1904-14.
Score: 0.004
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Seals DR, Hurley BF, Hagberg JM, Schultz J, Linder BJ, Natter L, Ehsani AA. Effects of training on systolic time intervals at rest and during isometric exercise in men and women 61 to 64 years old. Am J Cardiol. 1985 Mar 01; 55(6):797-800.
Score: 0.004
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Seals DR, Hagberg JM, Hurley BF, Ehsani AA, Holloszy JO. Endurance training in older men and women. I. Cardiovascular responses to exercise. J Appl Physiol Respir Environ Exerc Physiol. 1984 Oct; 57(4):1024-9.
Score: 0.004
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Seals DR, Hurley BF, Schultz J, Hagberg JM. Endurance training in older men and women II. Blood lactate response to submaximal exercise. J Appl Physiol Respir Environ Exerc Physiol. 1984 Oct; 57(4):1030-3.
Score: 0.004
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Seals DR, Hagberg JM, Hurley BF, Ehsani AA, Holloszy JO. Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women. JAMA. 1984 Aug 03; 252(5):645-9.
Score: 0.004
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Seals DR, Hagberg JM. The effect of exercise training on human hypertension: a review. Med Sci Sports Exerc. 1984 Jun; 16(3):207-15.
Score: 0.004
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Gates PE, Gentile CL, Seals DR, Christou DD. Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men. J Clin Endocrinol Metab. 2003 Oct; 88(10):4884-90.
Score: 0.004
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Moreau KL, Donato AJ, Seals DR, DeSouza CA, Tanaka H. Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women. Cardiovasc Res. 2003 Mar; 57(3):861-8.
Score: 0.004
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Pimentel AE, Gentile CL, Tanaka H, Seals DR, Gates PE. Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men. J Appl Physiol (1985). 2003 Jun; 94(6):2406-13.
Score: 0.004
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Bell C, Monahan KD, Donato AJ, Hunt BE, Seals DR, Beck KC. Use of acetylene breathing to determine cardiac output in young and older adults. Med Sci Sports Exerc. 2003 Jan; 35(1):58-64.
Score: 0.004
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Donato AJ, Tench K, Glueck DH, Seals DR, Eskurza I, Tanaka H. Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance. J Appl Physiol (1985). 2003 Feb; 94(2):764-9.
Score: 0.004
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Moreau KL, Donato AJ, Seals DR, Dinenno FA, Blackett SD, Hoetzer GL, Desouza CA, Tanaka H. Arterial intima-media thickness: site-specific associations with HRT and habitual exercise. Am J Physiol Heart Circ Physiol. 2002 Oct; 283(4):H1409-17.
Score: 0.004
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Tanaka H, Seals DR, Monahan KD, Clevenger CM, DeSouza CA, Dinenno FA. Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men. J Appl Physiol (1985). 2002 Apr; 92(4):1458-64.
Score: 0.004
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Eskurza I, Seals DR, DeSouza CA, Tanaka H. Pharmacologic versus flow-mediated assessments of peripheral vascular endothelial vasodilatory function in humans. Am J Cardiol. 2001 Nov 01; 88(9):1067-9.
Score: 0.003
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Bell C, Seals DR, Monroe MB, Day DS, Shapiro LF, Johnson DG, Jones PP. Tonic sympathetic support of metabolic rate is attenuated with age, sedentary lifestyle, and female sex in healthy adults. J Clin Endocrinol Metab. 2001 Sep; 86(9):4440-4.
Score: 0.003
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Dinenno FA, Seals DR, DeSouza CA, Tanaka H. Age-related decreases in basal limb blood flow in humans: time course, determinants and habitual exercise effects. J Physiol. 2001 Mar 01; 531(Pt 2):573-9.
Score: 0.003
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Rumantir MS, Vaz M, Jennings GL, Collier G, Kaye DM, Seals DR, Wiesner GH, Brunner-La Rocca HP, Esler MD. Neural mechanisms in human obesity-related hypertension. J Hypertens. 1999 Aug; 17(8):1125-33.
Score: 0.003
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Tanaka H, Clevenger CM, Jones PP, Seals DR, DeSouza CA. Influence of body fatness on the coronary risk profile of physically active postmenopausal women. Metabolism. 1998 Sep; 47(9):1112-20.
Score: 0.003
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Davy KP, Seals DR, Tanaka H. Augmented cardiopulmonary and integrative sympathetic baroreflexes but attenuated peripheral vasoconstriction with age. Hypertension. 1998 Aug; 32(2):298-304.
Score: 0.003
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Esler M, Vaz M, Collier G, Nestel P, Jennings G, Kaye D, Seals D, Lambert G. Leptin in human plasma is derived in part from the brain, and cleared by the kidneys. Lancet. 1998 Mar 21; 351(9106):879.
Score: 0.003
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Jasperse JL, Seals DR, Callister R. Active forearm blood flow adjustments to handgrip exercise in young and older healthy men. J Physiol. 1994 Jan 15; 474(2):353-60.
Score: 0.002
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Hagberg JM, Seals DR, Yerg JE, Gavin J, Gingerich R, Premachandra B, Holloszy JO. Metabolic responses to exercise in young and older athletes and sedentary men. J Appl Physiol (1985). 1988 Aug; 65(2):900-8.
Score: 0.001
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Allen WK, Seals DR, Hurley BF, Ehsani AA, Hagberg JM. Lactate threshold and distance-running performance in young and older endurance athletes. J Appl Physiol (1985). 1985 Apr; 58(4):1281-4.
Score: 0.001
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Yerg JE, Seals DR, Hagberg JM, Holloszy JO. Effect of endurance exercise training on ventilatory function in older individuals. J Appl Physiol (1985). 1985 Mar; 58(3):791-4.
Score: 0.001
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Ehsani AA, Biello D, Seals DR, Austin MB, Schultz J. The effect of left ventricular systolic function on maximal aerobic exercise capacity in asymptomatic patients with coronary artery disease. Circulation. 1984 Oct; 70(4):552-60.
Score: 0.001
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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