RandallWilkeningRandall B Wilkening39.74403510000000-104.83605940000000838Wilkening, RandallB303/724-2872Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 824324Authorship 834542Authorship 852023Authorship 859443Authorship 863133Authorship 867872Authorship 873113Authorship 902925Authorship 121240525516551Houin SS, Rozance PJ, Brown LD, Hay WW, Wilkening RB, Thorn SRAmerican journal of physiology. Endocrinology and metabolismHouin SS, Rozance PJ, Brown LD, Hay WW, Wilkening RB, Thorn SR. Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemia. Am J Physiol Endocrinol Metab. 2015 Feb 15; 308(4):E306-14.Am J Physiol Endocrinol Metab2014-12-16T00:00:002014Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemia.Authorship 93313Authorship 947977Authorship 957255Authorship 9635724056337Wilkening RB, Battaglia FC, Meschia GJournal of developmental physiologyWilkening RB, Battaglia FC, Meschia G. The relationship of umbilical glucose uptake to uterine blood flow. J Dev Physiol. 1985 Oct; 7(5):313-9.J Dev Physiol1985-10-01T00:00:001985The relationship of umbilical glucose uptake to uterine blood flow.6624905Hay WW, Sparks JW, Wilkening RB, Battaglia FC, Meschia GThe American journal of physiologyHay WW, Sparks JW, Wilkening RB, Battaglia FC, Meschia G. Partition of maternal glucose production between conceptus and maternal tissues in sheep. Am J Physiol. 1983 Oct; 245(4):E347-50.Am J Physiol1983-10-01T00:00:001983Partition of maternal glucose production between conceptus and maternal tissues in sheep.6859277Wilkening RB, Meschia GThe American journal of physiologyWilkening RB, Meschia G. Fetal oxygen uptake, oxygenation, and acid-base balance as a function of uterine blood flow. Am J Physiol. 1983 Jun; 244(6):H749-55.Am J Physiol1983-06-01T00:00:001983Fetal oxygen uptake, oxygenation, and acid-base balance as a function of uterine blood flow.7733270Vaughn PR, Lobo C, Battaglia FC, Fennessey PV, Wilkening RB, Meschia GThe American journal of physiologyVaughn PR, Lobo C, Battaglia FC, Fennessey PV, Wilkening RB, Meschia G. Glutamine-glutamate exchange between placenta and fetal liver. Am J Physiol. 1995 Apr; 268(4 Pt 1):E705-11.Am J Physiol1995-04-01T00:00:001995Glutamine-glutamate exchange between placenta and fetal liver.7914073Moores RR, Vaughn PR, Battaglia FC, Fennessey PV, Wilkening RB, Meschia GThe American journal of physiologyMoores RR, Vaughn PR, Battaglia FC, Fennessey PV, Wilkening RB, Meschia G. Glutamate metabolism in fetus and placenta of late-gestation sheep. Am J Physiol. 1994 Jul; 267(1 Pt 2):R89-96.Am J Physiol1994-07-01T00:00:001994Glutamate metabolism in fetus and placenta of late-gestation sheep.8916211Geddie G, Moores R, Meschia G, Fennessey P, Wilkening R, Battaglia FCPlacentaGeddie G, Moores R, Meschia G, Fennessey P, Wilkening R, Battaglia FC. Comparison of leucine, serine and glycine transport across the ovine placenta. Placenta. 1996 Nov; 17(8):619-27.Placenta1996-11-01T00:00:001996Comparison of leucine, serine and glycine transport across the ovine placenta.9029646Barbera A, Wilkening RB, Teng C, Battaglia FC, Meschia GPediatric researchBarbera A, Wilkening RB, Teng C, Battaglia FC, Meschia G. Metabolic alterations in the fetal hepatic and umbilical circulations during glucocorticoid-induced parturition in sheep. Pediatr Res. 1997 Feb; 41(2):242-8.Pediatr Res1997-02-01T00:00:001997Metabolic alterations in the fetal hepatic and umbilical circulations during glucocorticoid-induced parturition in sheep.7065203Wilkening RB, Anderson S, Martensson L, Meschia GThe American journal of physiologyWilkening RB, Anderson S, Martensson L, Meschia G. Placental transfer as a function of uterine blood flow. Am J Physiol. 1982 Mar; 242(3):H429-36.Am J Physiol1982-03-01T00:00:001982Placental transfer as a function of uterine blood flow.7466261Battaglia FC, Wilkening RBLa Revue du praticienBattaglia FC, Wilkening RB. [Care of very low birth weight newborn infants]. Rev Prat. 1981 Jan 21; 31(5):353-4, 357-8, 361-3.Rev Prat1981-01-21T00:00:001981[Care of very low birth weight newborn infants].7483169Battaglia FC, Wilkening R, Meschia GTransactions of the American Clinical and Climatological AssociationBattaglia FC, Wilkening R, Meschia G. Unique organ specific characteristics of amino acid metabolism in early development. Trans Am Clin Climatol Assoc. 1995; 106:141-9; discussion 149-50.Trans Am Clin Climatol Assoc1995-01-01T00:00:001995Unique organ specific characteristics of amino acid metabolism in early development.1443231Boyle DW, Meschia G, Wilkening RBThe American journal of physiologyBoyle DW, Meschia G, Wilkening RB. Metabolic adaptation of fetal hindlimb to severe, nonlethal hypoxia. Am J Physiol. 1992 Nov; 263(5 Pt 2):R1130-5.Am J Physiol1992-11-01T00:00:001992Metabolic adaptation of fetal hindlimb to severe, nonlethal hypoxia.Authorship 144632727170658Culpepper C, Wesolowski SR, Benjamin J, Bruce JL, Brown LD, Jonker SS, Wilkening RB, Hay WW, Rozance PJAmerican journal of physiology. Regulatory, integrative and comparative physiologyCulpepper C, Wesolowski SR, Benjamin J, Bruce JL, Brown LD, Jonker SS, Wilkening RB, Hay WW, Rozance PJ. Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep. Am J Physiol Regul Integr Comp Physiol. 2016 07 01; 311(1):R200-8.Am J Physiol Regul Integr Comp Physiol2016-05-11T00:00:002016Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep.1502133Wilkening RB, Meschia GPlacentaWilkening RB, Meschia G. Current topic: comparative physiology of placental oxygen transport. Placenta. 1992 Jan-Feb; 13(1):1-15.Placenta1992-01-01T00:00:001992Current topic: comparative physiology of placental oxygen transport.8414836Abman SH, Kinsella JP, Schaffer MS, Wilkening RBPediatricsAbman SH, Kinsella JP, Schaffer MS, Wilkening RB. Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension. Pediatrics. 1993 Oct; 92(4):606-9.Pediatrics1993-10-01T00:00:001993Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension.10780940Timmerman M, Teng C, Wilkening RB, Fennessey P, Battaglia FC, Meschia GAmerican journal of physiology. Endocrinology and metabolismTimmerman M, Teng C, Wilkening RB, Fennessey P, Battaglia FC, Meschia G. Effect of dexamethasone on fetal hepatic glutamine-glutamate exchange. Am J Physiol Endocrinol Metab. 2000 May; 278(5):E839-45.Am J Physiol Endocrinol Metab2000-05-01T00:00:002000Effect of dexamethasone on fetal hepatic glutamine-glutamate exchange.8638698Ross JC, Fennessey PV, Wilkening RB, Battaglia FC, Meschia GThe American journal of physiologyRoss JC, Fennessey PV, Wilkening RB, Battaglia FC, Meschia G. Placental transport and fetal utilization of leucine in a model of fetal growth retardation. Am J Physiol. 1996 Mar; 270(3 Pt 1):E491-503.Am J Physiol1996-03-01T00:00:001996Placental transport and fetal utilization of leucine in a model of fetal growth retardation.11120656Paolini CL, Meschia G, Fennessey PV, Pike AW, Teng C, Battaglia FC, Wilkening RBAmerican journal of physiology. Endocrinology and metabolismPaolini CL, Meschia G, Fennessey PV, Pike AW, Teng C, Battaglia FC, Wilkening RB. An in vivo study of ovine placental transport of essential amino acids. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E31-9.Am J Physiol Endocrinol Metab2001-01-01T00:00:002001An in vivo study of ovine placental transport of essential amino acids.1415644Thureen PJ, Trembler KA, Meschia G, Makowski EL, Wilkening RBThe American journal of physiologyThureen PJ, Trembler KA, Meschia G, Makowski EL, Wilkening RB. Placental glucose transport in heat-induced fetal growth retardation. Am J Physiol. 1992 Sep; 263(3 Pt 2):R578-85.Am J Physiol1992-09-01T00:00:001992Placental glucose transport in heat-induced fetal growth retardation.11945079Regnault TR, Orbus RJ, de Vrijer B, Davidsen ML, Galan HL, Wilkening RB, Anthony RVPlacentaRegnault TR, Orbus RJ, de Vrijer B, Davidsen ML, Galan HL, Wilkening RB, Anthony RV. Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR). Placenta. 2002 Feb-Mar; 23(2-3):132-44.Placenta2002-02-01T00:00:002002Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR).12524480Timmerman M, Wilkening RB, Regnault TRExperimental biology and medicine (Maywood, N.J.)Timmerman M, Wilkening RB, Regnault TR. Induction of glutamate dehydrogenase in the ovine fetal liver by dexamethasone infusion during late gestation. Exp Biol Med (Maywood). 2003 Jan; 228(1):100-5.Exp Biol Med (Maywood)2003-01-01T00:00:002003Induction of glutamate dehydrogenase in the ovine fetal liver by dexamethasone infusion during late gestation.12740423Regnault TR, de Vrijer B, Galan HL, Davidsen ML, Trembler KA, Battaglia FC, Wilkening RB, Anthony RVThe Journal of physiologyRegnault TR, de Vrijer B, Galan HL, Davidsen ML, Trembler KA, Battaglia FC, Wilkening RB, Anthony RV. The relationship between transplacental O2 diffusion and placental expression of PlGF, VEGF and their receptors in a placental insufficiency model of fetal growth restriction. J Physiol. 2003 Jul 15; 550(Pt 2):641-56.J Physiol2003-05-09T00:00:002003The relationship between transplacental O2 diffusion and placental expression of PlGF, VEGF and their receptors in a placental insufficiency model of fetal growth restriction.Authorship 156398828100476Benjamin JS, Culpepper CB, Brown LD, Wesolowski SR, Jonker SS, Davis MA, Limesand SW, Wilkening RB, Hay WW, Rozance PJAmerican journal of physiology. Regulatory, integrative and comparative physiologyBenjamin JS, Culpepper CB, Brown LD, Wesolowski SR, Jonker SS, Davis MA, Limesand SW, Wilkening RB, Hay WW, Rozance PJ. Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep. Am J Physiol Regul Integr Comp Physiol. 2017 04 01; 312(4):R492-R500.Am J Physiol Regul Integr Comp Physiol2017-01-18T00:00:002017Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep.14625207J?zwik M, Teng C, Wilkening RB, Meschia G, Battaglia FCAmerican journal of physiology. Endocrinology and metabolismJ?zwik M, Teng C, Wilkening RB, Meschia G, Battaglia FC. Reciprocal inhibition of umbilical uptake within groups of amino acids. Am J Physiol Endocrinol Metab. 2004 Mar; 286(3):E376-83.Am J Physiol Endocrinol Metab2003-11-18T00:00:002003Reciprocal inhibition of umbilical uptake within groups of amino acids.1Professor3Asst Professor2Assoc Professor1973090Truog RD, Accurso FJ, Wilkening RBDevelopmental pharmacology and therapeuticsTruog RD, Accurso FJ, Wilkening RB. Fetal pulmonary vasodilation by histamine: response to H1 and H2 stimulation. Dev Pharmacol Ther. 1990; 14(3):180-6.Dev Pharmacol Ther1990-01-01T00:00:001990Fetal pulmonary vasodilation by histamine: response to H1 and H2 stimulation.15837069Regnault TR, Friedman JE, Wilkening RB, Anthony RV, Hay WWPlacentaRegnault TR, Friedman JE, Wilkening RB, Anthony RV, Hay WW. Fetoplacental transport and utilization of amino acids in IUGR--a review. Placenta. 2005 Apr; 26 Suppl A:S52-62.Placenta2005-04-01T00:00:002005Fetoplacental transport and utilization of amino acids in IUGR--a review.15806809Battaglia FC, Regnault TR, Teng C, Wilkening RB, Meschia GForum of nutritionBattaglia FC, Regnault TR, Teng C, Wilkening RB, Meschia G. The role of glutamate in fetal hepatic glucogenesis. Forum Nutr. 2003; 56:82-4.Forum Nutr2003-01-01T00:00:002003The role of glutamate in fetal hepatic glucogenesis.16306198Hagen AS, Orbus RJ, Wilkening RB, Regnault TR, Anthony RVPediatric researchHagen AS, Orbus RJ, Wilkening RB, Regnault TR, Anthony RV. Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction. Pediatr Res. 2005 Dec; 58(6):1228-32.Pediatr Res2005-12-01T00:00:002005Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction.2001-06-30NIHHAY, WILLIAM W1985-09-30METABOLIC REGULATION OF FETAL GROWTHP01HD0207612008-06-30NIHWILKENING, RANDALL B2002-07-01Fetoplacental amino acid metabolism in IUGR pregnanciesR01HD041505Principal InvestigatorCo-Principal Investigator2259706Molina RD, Meschia G, Wilkening RBProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Molina RD, Meschia G, Wilkening RB. Uterine blood flow, oxygen and glucose uptakes at mid-gestation in the sheep. Proc Soc Exp Biol Med. 1990 Dec; 195(3):379-85.Proc Soc Exp Biol Med1990-12-01T00:00:001990Uterine blood flow, oxygen and glucose uptakes at mid-gestation in the sheep.2395609Boyle DW, Hirst K, Zerbe GO, Meschia G, Wilkening RBPediatric researchBoyle DW, Hirst K, Zerbe GO, Meschia G, Wilkening RB. Fetal hind limb oxygen consumption and blood flow during acute graded hypoxia. Pediatr Res. 1990 Aug; 28(2):94-100.Pediatr Res1990-08-01T00:00:001990Fetal hind limb oxygen consumption and blood flow during acute graded hypoxia.19342452Thorn SR, Regnault TR, Brown LD, Rozance PJ, Keng J, Roper M, Wilkening RB, Hay WW, Friedman JEEndocrinologyThorn SR, Regnault TR, Brown LD, Rozance PJ, Keng J, Roper M, Wilkening RB, Hay WW, Friedman JE. Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology. 2009 Jul; 150(7):3021-30.Endocrinology2009-04-02T00:00:002009Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle.Authorship 1702541028940557Rozance PJ, Zastoupil L, Wesolowski SR, Goldstrohm DA, Strahan B, Cree-Green M, Sheffield-Moore M, Meschia G, Hay WW, Wilkening RB, Brown LDThe Journal of physiologyRozance PJ, Zastoupil L, Wesolowski SR, Goldstrohm DA, Strahan B, Cree-Green M, Sheffield-Moore M, Meschia G, Hay WW, Wilkening RB, Brown LD. Skeletal muscle protein accretion rates and hindlimb growth are reduced in late gestation intrauterine growth-restricted fetal sheep. J Physiol. 2018 01 01; 596(1):67-82.J Physiol2017-10-26T00:00:002017Skeletal muscle protein accretion rates and hindlimb growth are reduced in late gestation intrauterine growth-restricted fetal sheep.11150831Timmerman M, Teng C, Wilkening RB, Chung M, Battaglia FCBiology of the neonateTimmerman M, Teng C, Wilkening RB, Chung M, Battaglia FC. Net amino acid flux across the fetal liver and placenta during spontaneous ovine parturition. Biol Neonate. 2001 Jan; 79(1):54-60.Biol Neonate2001-01-01T00:00:002001Net amino acid flux across the fetal liver and placenta during spontaneous ovine parturition.11356809Galan HL, Regnault TR, Le Cras TD, Tyson RW, Anthony RV, Wilkening RB, Abman SHJournal of applied physiology (Bethesda, Md. : 1985)Galan HL, Regnault TR, Le Cras TD, Tyson RW, Anthony RV, Wilkening RB, Abman SH. Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction. J Appl Physiol (1985). 2001 Jun; 90(6):2420-6.J Appl Physiol (1985)2001-06-01T00:00:002001Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction.2923240Wilkening RB, Meschia GThe American journal of physiologyWilkening RB, Meschia G. Effect of umbilical blood flow on transplacental diffusion of ethanol and oxygen. Am J Physiol. 1989 Mar; 256(3 Pt 2):H813-20.Am J Physiol1989-03-01T00:00:001989Effect of umbilical blood flow on transplacental diffusion of ethanol and oxygen.3340622Accurso FJ, Wilkening RBProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Accurso FJ, Wilkening RB. Temporal response of the fetal pulmonary circulation to pharmacologic vasodilators. Proc Soc Exp Biol Med. 1988 Jan; 187(1):89-98.Proc Soc Exp Biol Med1988-01-01T00:00:001988Temporal response of the fetal pulmonary circulation to pharmacologic vasodilators.3559063Bell AW, Wilkening RB, Meschia GJournal of developmental physiologyBell AW, Wilkening RB, Meschia G. Some aspects of placental function in chronically heat-stressed ewes. J Dev Physiol. 1987 Feb; 9(1):17-29.J Dev Physiol1987-02-01T00:00:001987Some aspects of placental function in chronically heat-stressed ewes.3353399Wilkening RB, Boyle DW, Meschia GProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Wilkening RB, Boyle DW, Meschia G. Measurement of blood flow and oxygen consumption in the pelvic limb of fetal sheep. Proc Soc Exp Biol Med. 1988 Apr; 187(4):498-505.Proc Soc Exp Biol Med1988-04-01T00:00:001988Measurement of blood flow and oxygen consumption in the pelvic limb of fetal sheep.3354706Wilkening RB, Molina RD, Meschia GThe American journal of physiologyWilkening RB, Molina RD, Meschia G. Placental oxygen transport in sheep with different hemoglobin types. Am J Physiol. 1988 Apr; 254(4 Pt 2):R585-9.Am J Physiol1988-04-01T00:00:001988Placental oxygen transport in sheep with different hemoglobin types.3548832Wilkening RB, Molina RD, Battaglia FC, Meschia GBiology of the neonateWilkening RB, Molina RD, Battaglia FC, Meschia G. Effect of insulin on glucose/oxygen and lactate/oxygen quotients across the hindlimb of fetal lambs. Biol Neonate. 1987; 51(1):18-23.Biol Neonate1987-01-01T00:00:001987Effect of insulin on glucose/oxygen and lactate/oxygen quotients across the hindlimb of fetal lambs.3703876Wilkening RBProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Wilkening RB. Transplacental diffusion in a bicornuate uterus: comparison of uterine blood flow and oxygen uptake between horns. Proc Soc Exp Biol Med. 1986 Jun; 182(2):237-44.Proc Soc Exp Biol Med1986-06-01T00:00:001986Transplacental diffusion in a bicornuate uterus: comparison of uterine blood flow and oxygen uptake between horns.3797106Abman SH, Wilkening RB, Ward RM, Accurso FJPediatric researchAbman SH, Wilkening RB, Ward RM, Accurso FJ. Adaptation of fetal pulmonary blood flow to local infusion of tolazoline. Pediatr Res. 1986 Nov; 20(11):1131-5.Pediatr Res1986-11-01T00:00:001986Adaptation of fetal pulmonary blood flow to local infusion of tolazoline.12657509Paolini CL, Teng C, J?zwik M, Meschia G, Wilkening RB, Battaglia FCPlacentaPaolini CL, Teng C, J?zwik M, Meschia G, Wilkening RB, Battaglia FC. Umbilical threonine uptake during maternal threonine infusion in sheep. Placenta. 2003 Apr; 24(4):354-60.Placenta2003-04-01T00:00:002003Umbilical threonine uptake during maternal threonine infusion in sheep.6412239Hay WW, Myers SA, Sparks JW, Wilkening RB, Meschia G, Battaglia FCProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)Hay WW, Myers SA, Sparks JW, Wilkening RB, Meschia G, Battaglia FC. Glucose and lactate oxidation rates in the fetal lamb. Proc Soc Exp Biol Med. 1983 Sep; 173(4):553-63.Proc Soc Exp Biol Med1983-09-01T00:00:001983Glucose and lactate oxidation rates in the fetal lamb.6703052Hay WW, Sparks JW, Wilkening RB, Battaglia FC, Meschia GThe American journal of physiologyHay WW, Sparks JW, Wilkening RB, Battaglia FC, Meschia G. Fetal glucose uptake and utilization as functions of maternal glucose concentration. Am J Physiol. 1984 Mar; 246(3 Pt 1):E237-42.Am J Physiol1984-03-01T00:00:001984Fetal glucose uptake and utilization as functions of maternal glucose concentration.6725882Wilkening RB, Anderson S, Meschia GJournal of developmental physiologyWilkening RB, Anderson S, Meschia G. Non-steady state placental transfer of highly diffusible molecules. J Dev Physiol. 1984 Apr; 6(2):121-9.J Dev Physiol1984-04-01T00:00:001984Non-steady state placental transfer of highly diffusible molecules.8214057Guyton TS, De Wilt H, Fennessey PV, Meschia G, Wilkening RB, Battaglia FCThe American journal of physiologyGuyton TS, De Wilt H, Fennessey PV, Meschia G, Wilkening RB, Battaglia FC. Alanine umbilical uptake, disposal rate, and decarboxylation rate in the fetal lamb. Am J Physiol. 1993 Sep; 265(3 Pt 1):E497-503.Am J Physiol1993-09-01T00:00:001993Alanine umbilical uptake, disposal rate, and decarboxylation rate in the fetal lamb.8304446Wilkening RB, Boyle DW, Teng C, Meschia G, Battaglia FCThe American journal of physiologyWilkening RB, Boyle DW, Teng C, Meschia G, Battaglia FC. Amino acid uptake by the fetal ovine hindlimb under normal and euglycemic hyperinsulinemic states. Am J Physiol. 1994 Jan; 266(1 Pt 1):E72-8.Am J Physiol1994-01-01T00:00:001994Amino acid uptake by the fetal ovine hindlimb under normal and euglycemic hyperinsulinemic states.8448255Wilkening RB, Boyle DW, Meschia GBiology of the neonateWilkening RB, Boyle DW, Meschia G. Fetal pH improvement after 24 h of severe, nonlethal hypoxia. Biol Neonate. 1993; 63(2):129-32.Biol Neonate1993-01-01T00:00:001993Fetal pH improvement after 24 h of severe, nonlethal hypoxia.9176191Anderson AH, Fennessey PV, Meschia G, Wilkening RB, Battaglia FCThe American journal of physiologyAnderson AH, Fennessey PV, Meschia G, Wilkening RB, Battaglia FC. Placental transport of threonine and its utilization in the normal and growth-restricted fetus. Am J Physiol. 1997 May; 272(5 Pt 1):E892-900.Am J Physiol1997-05-01T00:00:001997Placental transport of threonine and its utilization in the normal and growth-restricted fetus.15672036Galan HL, Anthony RV, Rigano S, Parker TA, de Vrijer B, Ferrazzi E, Wilkening RB, Regnault TRAmerican journal of obstetrics and gynecologyGalan HL, Anthony RV, Rigano S, Parker TA, de Vrijer B, Ferrazzi E, Wilkening RB, Regnault TR. Fetal hypertension and abnormal Doppler velocimetry in an ovine model of intrauterine growth restriction. Am J Obstet Gynecol. 2005 Jan; 192(1):272-9.Am J Obstet Gynecol2005-01-01T00:00:002005Fetal hypertension and abnormal Doppler velocimetry in an ovine model of intrauterine growth restriction.9843735Timmerman M, Chung M, Wilkening RB, Fennessey PV, Battaglia FC, Meschia GThe American journal of physiologyTimmerman M, Chung M, Wilkening RB, Fennessey PV, Battaglia FC, Meschia G. Relationship of fetal alanine uptake and placental alanine metabolism to maternal plasma alanine concentration. Am J Physiol. 1998 12; 275(6):E942-50.Am J Physiol1998-12-01T00:00:001998Relationship of fetal alanine uptake and placental alanine metabolism to maternal plasma alanine concentration.10095145Holcomb RG, Wilkening RBBiology of the neonateHolcomb RG, Wilkening RB. Fetal hepatic oxygen consumption under normal conditions in the fetal lamb. Biol Neonate. 1999 May; 75(5):310-8.Biol Neonate1999-05-01T00:00:001999Fetal hepatic oxygen consumption under normal conditions in the fetal lamb.10467235Regnault TR, Orbus RJ, Battaglia FC, Wilkening RB, Anthony RVThe Journal of endocrinologyRegnault TR, Orbus RJ, Battaglia FC, Wilkening RB, Anthony RV. Altered arterial concentrations of placental hormones during maximal placental growth in a model of placental insufficiency. J Endocrinol. 1999 Sep; 162(3):433-42.J Endocrinol1999-09-01T00:00:001999Altered arterial concentrations of placental hormones during maximal placental growth in a model of placental insufficiency.16962658Regnault TR, de Vrijer B, Galan HL, Wilkening RB, Battaglia FC, Meschia GPlacentaRegnault TR, de Vrijer B, Galan HL, Wilkening RB, Battaglia FC, Meschia G. Development and mechanisms of fetal hypoxia in severe fetal growth restriction. Placenta. 2007 Jul; 28(7):714-23.Placenta2006-09-07T00:00:002006Development and mechanisms of fetal hypoxia in severe fetal growth restriction.11856817Teng CC, Tjoa S, Fennessey PV, Wilkening RB, Battaglia FCExperimental biology and medicine (Maywood, N.J.)Teng CC, Tjoa S, Fennessey PV, Wilkening RB, Battaglia FC. Transplacental carbohydrate and sugar alcohol concentrations and their uptakes in ovine pregnancy. Exp Biol Med (Maywood). 2002 Mar; 227(3):189-95.Exp Biol Med (Maywood)2002-03-01T00:00:002002Transplacental carbohydrate and sugar alcohol concentrations and their uptakes in ovine pregnancy.14634591Wilkes PT, Meschia G, Teng C, Zhu Y, Wilkening RB, Battaglia FCAmerican journal of obstetrics and gynecologyWilkes PT, Meschia G, Teng C, Zhu Y, Wilkening RB, Battaglia FC. The effect of an elevated maternal lysine concentration on placental lysine transport in pregnant sheep. Am J Obstet Gynecol. 2003 Nov; 189(5):1494-500.Am J Obstet Gynecol2003-11-01T00:00:002003The effect of an elevated maternal lysine concentration on placental lysine transport in pregnant sheep.1901461Wilkening RB, Meschia GThe American journal of physiologyWilkening RB, Meschia G. Effect of occluding one umbilical artery on placental oxygen transport. Am J Physiol. 1991 Apr; 260(4 Pt 2):H1319-25.Am J Physiol1991-04-01T00:00:001991Effect of occluding one umbilical artery on placental oxygen transport.15315907de Vrijer B, Regnault TR, Wilkening RB, Meschia G, Battaglia FCAmerican journal of physiology. Endocrinology and metabolismde Vrijer B, Regnault TR, Wilkening RB, Meschia G, Battaglia FC. Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction. Am J Physiol Endocrinol Metab. 2004 Dec; 287(6):E1114-24.Am J Physiol Endocrinol Metab2004-08-17T00:00:002004Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction.2022570Accurso FJ, Abman SH, Wilkening RB, Worthen GS, Henson PJournal of applied physiology (Bethesda, Md. : 1985)Accurso FJ, Abman SH, Wilkening RB, Worthen GS, Henson P. Fetal pulmonary vasodilation after exogenous platelet-activating factor. J Appl Physiol (1985). 1991 Feb; 70(2):778-87.J Appl Physiol (1985)1991-02-01T00:00:001991Fetal pulmonary vasodilation after exogenous platelet-activating factor.16966353de Vrijer B, Davidsen ML, Wilkening RB, Anthony RV, Regnault TRPediatric researchde Vrijer B, Davidsen ML, Wilkening RB, Anthony RV, Regnault TR. Altered placental and fetal expression of IGFs and IGF-binding proteins associated with intrauterine growth restriction in fetal sheep during early and mid-pregnancy. Pediatr Res. 2006 Nov; 60(5):507-12.Pediatr Res2006-09-11T00:00:002006Altered placental and fetal expression of IGFs and IGF-binding proteins associated with intrauterine growth restriction in fetal sheep during early and mid-pregnancy.2390540Wilkening RB, Boyle DWBiology of the neonateWilkening RB, Boyle DW. Effect of neuromuscular blockade on fetal oxidative metabolism. Biol Neonate. 1990; 58(1):57-60.Biol Neonate1990-01-01T00:00:001990Effect of neuromuscular blockade on fetal oxidative metabolism.20576742Regnault TR, Teng C, de Vrijer B, Galan HL, Wilkening RB, Battaglia FCExperimental biology and medicine (Maywood, N.J.)Regnault TR, Teng C, de Vrijer B, Galan HL, Wilkening RB, Battaglia FC. The tissue and plasma concentration of polyols and sugars in sheep intrauterine growth retardation. Exp Biol Med (Maywood). 2010 Aug; 235(8):999-1006.Exp Biol Med (Maywood)2010-06-24T00:00:002010The tissue and plasma concentration of polyols and sugars in sheep intrauterine growth retardation.2889374Abman SH, Accurso FJ, Wilkening RB, Meschia GThe American journal of physiologyAbman SH, Accurso FJ, Wilkening RB, Meschia G. Persistent fetal pulmonary hypoperfusion after acute hypoxia. Am J Physiol. 1987 Oct; 253(4 Pt 2):H941-8.Am J Physiol1987-10-01T00:00:001987Persistent fetal pulmonary hypoperfusion after acute hypoxia.23407119Regnault TR, de Vrijer B, Galan HL, Wilkening RB, Battaglia FC, Meschia GPediatric researchRegnault TR, de Vrijer B, Galan HL, Wilkening RB, Battaglia FC, Meschia G. Umbilical uptakes and transplacental concentration ratios of amino acids in severe fetal growth restriction. Pediatr Res. 2013 May; 73(5):602-11.Pediatr Res2013-02-13T00:00:002013Umbilical uptakes and transplacental concentration ratios of amino acids in severe fetal growth restriction.3081980Accurso FJ, Alpert B, Wilkening RB, Petersen RG, Meschia GRespiration physiologyAccurso FJ, Alpert B, Wilkening RB, Petersen RG, Meschia G. Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension. Respir Physiol. 1986 Jan; 63(1):43-52.Respir Physiol1986-01-01T00:00:001986Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension.3221058Accurso FJ, Wilkening RBJournal of developmental physiologyAccurso FJ, Wilkening RB. Fetal pulmonary vasodilation and vasoreactivity during metabolic acidaemia. J Dev Physiol. 1988 Oct; 10(5):411-21.J Dev Physiol1988-10-01T00:00:001988Fetal pulmonary vasodilation and vasoreactivity during metabolic acidaemia.2782432Wilkening RB, Boyle DW, Meschia GThe American journal of physiologyWilkening RB, Boyle DW, Meschia G. Fetal neuromuscular blockade: effect on oxygen demand and placental transport. Am J Physiol. 1989 Sep; 257(3 Pt 2):H734-8.Am J Physiol1989-09-01T00:00:001989Fetal neuromuscular blockade: effect on oxygen demand and placental transport.2910053Conrad PD, Wilkening RB, Rosenberg AAAmerican journal of diseases of children (1960)Conrad PD, Wilkening RB, Rosenberg AA. Safety of newborn discharge in less than 36 hours in an indigent population. Am J Dis Child. 1989 Jan; 143(1):98-101.Am J Dis Child1989-01-01T00:00:001989Safety of newborn discharge in less than 36 hours in an indigent population.D012756Living Beings1407690.809249SheepD010920Anatomy1426480.626067Placenta13065 East 17th Avenue2TCHChildren's Hospital13065 East 17th AvenueAurora80045-2532COD005317Disorders924730.674958Fetal Growth RetardationD005333Anatomy2286990.713713FetusSOM-OB/GYN MFM GENERAL OPSSOM-OB/GYN RS GENERAL OPSPULM&SLEEPMEDJaneStremmingJane Elizabeth Stremming39.74403510000000-104.8360594000000015639Stremming, JaneAsst ProfessorD014599Anatomy911970.885632UterusSOM-PEDSNeonatologyUniversity of Colorado Denver - Anschutz Medical CampusThomasParkerThomas A Parker39.74403510000000-104.836059400000001396Parker, ThomasProfessorPaulRozancePaul J Rozance39.74403510000000-104.836059400000001601Rozance, PaulProfessorStephanieWesolowskiStephanie R. Wesolowski39.74403510000000-104.836059400000002753Wesolowski, StephanieAssociate ProfessorClydeWrightClyde J Wright39.74403510000000-104.836059400000005158Wright, ClydeProfessorStevenAbmanSteven H Abman39.74403510000000-104.83605940000000518Abman, StevenProfessor1.36420.00328479277research areas0.6185420.016474614coauthor of48.01233.2268560similar to1172selected publicationsJamesBarryJames S Barry39.74403510000000-104.83605940000000905Barry, JamesAssociate ProfessorAuthorship 114155LauraBrownLaura D Brown39.74403510000000-104.83605940000000638Brown, LauraProfessorHenryGalanHenry Louis Galan39.74403280000000-104.84081040000000761Galan, HenryProfessorAuthorship 116315Authorship 13341Authorship 133601Authorship 136791Authorship 146661Authorship 152702Authorship 222134532538259Zarate MA, Wesolowski SR, Nguyen LM, De Dios RK, Wilkening RB, Rozance PJ, Wright CJInnate immunityZarate MA, Wesolowski SR, Nguyen LM, De Dios RK, Wilkening RB, Rozance PJ, Wright CJ. In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep. Innate Immun. 2020 10; 26(7):549-564.Innate Immun2020-06-14T00:00:002020In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep.Authorship 170644Authorship 182083Authorship 203572Authorship 208551Authorship 217697Authorship 230245Authorship 237451Authorship 251015Authorship 282535637126847Kyllo HM, Wang D, Lorca RA, Julian CG, Moore LG, Wilkening RB, Rozance PJ, Brown LD, Wesolowski SRAmerican journal of physiology. Endocrinology and metabolismKyllo HM, Wang D, Lorca RA, Julian CG, Moore LG, Wilkening RB, Rozance PJ, Brown LD, Wesolowski SR. Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency. Am J Physiol Endocrinol Metab. 2023 06 01; 324(6):E556-E568.Am J Physiol Endocrinol Metab2023-04-26T00:00:002023Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency.true1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Asst ProfessorAsst Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1ProfessorProfessorAuthorship 301453Authorship 317483true1ProfessorProfessortrue1ProfessorProfessorAuthorship 335612Authorship 1037981822796107Clark JA, Alves S, Gundlah C, Rocha B, Birzin ET, Cai SJ, Flick R, Hayes E, Ho K, Warrier S, Pai L, Yudkovitz J, Fleischer R, Colwell L, Li S, Wilkinson H, Schaeffer J, Wilkening R, Mattingly E, Hammond M, Rohrer SPNeuropharmacologyClark JA, Alves S, Gundlah C, Rocha B, Birzin ET, Cai SJ, Flick R, Hayes E, Ho K, Warrier S, Pai L, Yudkovitz J, Fleischer R, Colwell L, Li S, Wilkinson H, Schaeffer J, Wilkening R, Mattingly E, Hammond M, Rohrer SP. Selective estrogen receptor-beta (SERM-beta) compounds modulate raphe nuclei tryptophan hydroxylase-1 (TPH-1) mRNA expression and cause antidepressant-like effects in the forced swim test. Neuropharmacology. 2012 Nov; 63(6):1051-63.Neuropharmacology2012-07-13T00:00:002012Selective estrogen receptor-beta (SERM-beta) compounds modulate raphe nuclei tryptophan hydroxylase-1 (TPH-1) mRNA expression and cause antidepressant-like effects in the forced swim test.Authorship 375082Authorship 383893Authorship 392507Authorship 399345Authorship 412831Authorship 413493Authorship 458464Authorship 50154Authorship 5062Authorship 507542Authorship 519824Authorship 523413Authorship 548031Authorship 559823Authorship 561943Authorship 577591Authorship 591001Authorship 59531Authorship 603843Authorship 615043Authorship 617434EricaMandellErica W. Mandell39.74403510000000-104.836059400000008960Mandell, EricaAssociate ProfessorThomasJanssonThomas Jansson39.74515960000000-104.840628000000008977Jansson, ThomasProfessorAuthorship 662824Authorship 669891Authorship 671971TheresaPowellTheresa L. Powell39.74403510000000-104.836059400000009180Powell, TheresaProfessorAuthorship 690715Authorship 699754Authorship 702513Authorship 704435Authorship 708692Authorship 740586Authorship 754901Authorship 761861Authorship 780793Authorship 785747Authorship 799396