MonikaFleshnerMonika R Fleshner40.00943840000000-105.27038960000000818Fleshner, MonikaR303/492-1483Professorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 823056Authorship 824162Authorship 833842Authorship 8363319Authorship 848657Authorship 856491Authorship 859277Authorship 868684Authorship 880962Authorship 889237Authorship 893738Authorship 899464Authorship 909751Authorship 913751Authorship 1211112Authorship 120896224405946Beninson LA, Fleshner MSeminars in immunologyBeninson LA, Fleshner M. Exosomes: an emerging factor in stress-induced immunomodulation. Semin Immunol. 2014 Oct; 26(5):394-401.Semin Immunol2014-01-06T00:00:002014Exosomes: an emerging factor in stress-induced immunomodulation.25455591Beninson LA, Fleshner MImmunology lettersBeninson LA, Fleshner M. Exosomes in fetal bovine serum dampen primary macrophage IL-1? response to lipopolysaccharide (LPS) challenge. Immunol Lett. 2015 Feb; 163(2):187-92.Immunol Lett2014-10-24T00:00:002014Exosomes in fetal bovine serum dampen primary macrophage IL-1? response to lipopolysaccharide (LPS) challenge.Authorship 9264114Authorship 927183Authorship 928891Authorship 932556Authorship 937051Authorship 942366Authorship 125310626016739Mika A, Van Treuren W, Gonz?lez A, Herrera JJ, Knight R, Fleshner MPloS oneMika A, Van Treuren W, Gonz?lez A, Herrera JJ, Knight R, Fleshner M. Exercise is More Effective at Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile versus Adult Male F344 Rats. PLoS One. 2015; 10(5):e0125889.PLoS One2015-05-27T00:00:002015Exercise is More Effective at Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile versus Adult Male F344 Rats.Authorship 125543325911267Zoladz PR, Park CR, Fleshner M, Diamond DMPhysiology & behaviorZoladz PR, Park CR, Fleshner M, Diamond DM. Psychosocial predator-based animal model of PTSD produces physiological and behavioral sequelae and a traumatic memory four months following stress onset. Physiol Behav. 2015 Aug 01; 147:183-92.Physiol Behav2015-04-22T00:00:002015Psychosocial predator-based animal model of PTSD produces physiological and behavioral sequelae and a traumatic memory four months following stress onset.Authorship 126168425640603Wright KP, Drake AL, Frey DJ, Fleshner M, Desouza CA, Gronfier C, Czeisler CABrain, behavior, and immunityWright KP, Drake AL, Frey DJ, Fleshner M, Desouza CA, Gronfier C, Czeisler CA. Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance. Brain Behav Immun. 2015 Jul; 47:24-34.Brain Behav Immun2015-01-29T00:00:002015Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance.Authorship 965841Authorship 967456Authorship 134082726555633Clark PJ, Amat J, McConnell SO, Ghasem PR, Greenwood BN, Maier SF, Fleshner MPloS oneClark PJ, Amat J, McConnell SO, Ghasem PR, Greenwood BN, Maier SF, Fleshner M. Running Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine Concentrations in the Rat Dorsal Striatum. PLoS One. 2015; 10(11):e0141898.PLoS One2015-11-10T00:00:002015Running Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine Concentrations in the Rat Dorsal Striatum.Authorship 134493826454156Mika A, Bouchet CA, Bunker P, Hellwinkel JE, Spence KG, Day HE, Campeau S, Fleshner M, Greenwood BNNeurobiology of learning and memoryMika A, Bouchet CA, Bunker P, Hellwinkel JE, Spence KG, Day HE, Campeau S, Fleshner M, Greenwood BN. Voluntary exercise during extinction of auditory fear conditioning reduces the relapse of fear associated with potentiated activity of striatal direct pathway neurons. Neurobiol Learn Mem. 2015 Nov; 125:224-35.Neurobiol Learn Mem2015-10-11T00:00:002015Voluntary exercise during extinction of auditory fear conditioning reduces the relapse of fear associated with potentiated activity of striatal direct pathway neurons.7588279Fleshner M, Deak T, Spencer RL, Laudenslager ML, Watkins LR, Maier SFEndocrinologyFleshner M, Deak T, Spencer RL, Laudenslager ML, Watkins LR, Maier SF. A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure. Endocrinology. 1995 Dec; 136(12):5336-42.Endocrinology1995-12-01T00:00:001995A long-term increase in basal levels of corticosterone and a decrease in corticosteroid-binding globulin after acute stressor exposure.7670884Fleshner M, Goehler LE, Hermann J, Relton JK, Maier SF, Watkins LRBrain research bulletinFleshner M, Goehler LE, Hermann J, Relton JK, Maier SF, Watkins LR. Interleukin-1 beta induced corticosterone elevation and hypothalamic NE depletion is vagally mediated. Brain Res Bull. 1995; 37(6):605-10.Brain Res Bull1995-01-01T00:00:001995Interleukin-1 beta induced corticosterone elevation and hypothalamic NE depletion is vagally mediated.7822481Fleshner M, Bellgrau D, Watkins LR, Laudenslager ML, Maier SFJournal of neuroimmunologyFleshner M, Bellgrau D, Watkins LR, Laudenslager ML, Maier SF. Stress-induced reduction in the rat mixed lymphocyte reaction is due to macrophages and not to changes in T cell phenotypes. J Neuroimmunol. 1995 Jan; 56(1):45-52.J Neuroimmunol1995-01-01T00:00:001995Stress-induced reduction in the rat mixed lymphocyte reaction is due to macrophages and not to changes in T cell phenotypes.7818221Maier SF, Watkins LR, Fleshner MThe American psychologistMaier SF, Watkins LR, Fleshner M. Psychoneuroimmunology. The interface between behavior, brain, and immunity. Am Psychol. 1994 Dec; 49(12):1004-17.Am Psychol1994-12-01T00:00:001994Psychoneuroimmunology. The interface between behavior, brain, and immunity.7850467Sutton LC, Fleshner M, Mazzeo R, Maier SF, Watkins LRBrain researchSutton LC, Fleshner M, Mazzeo R, Maier SF, Watkins LR. A permissive role of corticosterone in an opioid form of stress-induced analgesia: blockade of opiate analgesia is not due to stress-induced hormone release. Brain Res. 1994 Nov 07; 663(1):19-29.Brain Res1994-11-07T00:00:001994A permissive role of corticosterone in an opioid form of stress-induced analgesia: blockade of opiate analgesia is not due to stress-induced hormone release.7917027Diamond DM, Fleshner M, Rose GMBehavioural brain researchDiamond DM, Fleshner M, Rose GM. Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats. Behav Brain Res. 1994 May 30; 62(1):1-9.Behav Brain Res1994-05-30T00:00:001994Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats.8003769Lockwood LL, Silbert LH, Fleshner M, Laudenslager ML, Watkins LR, Maier SFBrain, behavior, and immunityLockwood LL, Silbert LH, Fleshner M, Laudenslager ML, Watkins LR, Maier SF. Morphine-induced decreases in in vivo antibody responses. Brain Behav Immun. 1994 Mar; 8(1):24-36.Brain Behav Immun1994-03-01T00:00:001994Morphine-induced decreases in in vivo antibody responses.Authorship 138770226647967Mika A, Fleshner MImmunology and cell biologyMika A, Fleshner M. Early-life exercise may promote lasting brain and metabolic health through gut bacterial metabolites. Immunol Cell Biol. 2016 Feb; 94(2):151-7.Immunol Cell Biol2015-12-09T00:00:002015Early-life exercise may promote lasting brain and metabolic health through gut bacterial metabolites.8391148Fleshner M, Watkins LR, Lockwood LL, Grahn RE, Gerhardt G, Meaney MJ, Laudenslager ML, Maier SFPsychoneuroendocrinologyFleshner M, Watkins LR, Lockwood LL, Grahn RE, Gerhardt G, Meaney MJ, Laudenslager ML, Maier SF. Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: a method for studying the stress-induced peripheral effects of glucocorticoids. Psychoneuroendocrinology. 1993; 18(4):251-63.Psychoneuroendocrinology1993-01-01T00:00:001993Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: a method for studying the stress-induced peripheral effects of glucocorticoids.8597472Diamond DM, Branch BJ, Fleshner M, Rose GMAnnals of the New York Academy of SciencesDiamond DM, Branch BJ, Fleshner M, Rose GM. Effects of dehydroepiandrosterone sulfate and stress on hippocampal electrophysiological plasticity. Ann N Y Acad Sci. 1995 Dec 29; 774:304-7.Ann N Y Acad Sci1995-12-29T00:00:001995Effects of dehydroepiandrosterone sulfate and stress on hippocampal electrophysiological plasticity.1344303Fleshner M, Watkins LR, Redd JM, Kruse CA, Bellgrau DCell transplantationFleshner M, Watkins LR, Redd JM, Kruse CA, Bellgrau D. A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats. Cell Transplant. 1992; 1(4):307-12.Cell Transplant1992-01-01T00:00:001992A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats.Authorship 140632127084809Fleshner M, Olivier KN, Shaw PA, Adjemian J, Strollo S, Claypool RJ, Folio L, Zelazny A, Holland SM, Prevots DRThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung DiseaseFleshner M, Olivier KN, Shaw PA, Adjemian J, Strollo S, Claypool RJ, Folio L, Zelazny A, Holland SM, Prevots DR. Mortality among patients with pulmonary non-tuberculous mycobacteria disease. Int J Tuberc Lung Dis. 2016 May; 20(5):582-7.Int J Tuberc Lung Dis2016-05-01T00:00:002016Mortality among patients with pulmonary non-tuberculous mycobacteria disease.Authorship 140836926833814Herrera JJ, Fedynska S, Ghasem PR, Wieman T, Clark PJ, Gray N, Loetz E, Campeau S, Fleshner M, Greenwood BNThe European journal of neuroscienceHerrera JJ, Fedynska S, Ghasem PR, Wieman T, Clark PJ, Gray N, Loetz E, Campeau S, Fleshner M, Greenwood BN. Neurochemical and behavioural indices of exercise reward are independent of exercise controllability. Eur J Neurosci. 2016 05; 43(9):1190-202.Eur J Neurosci2016-02-28T00:00:002016Neurochemical and behavioural indices of exercise reward are independent of exercise controllability.8864259Diamond DM, Fleshner M, Ingersoll N, Rose GMBehavioral neuroscienceDiamond DM, Fleshner M, Ingersoll N, Rose GM. Psychological stress impairs spatial working memory: relevance to electrophysiological studies of hippocampal function. Behav Neurosci. 1996 Aug; 110(4):661-72.Behav Neurosci1996-08-01T00:00:001996Psychological stress impairs spatial working memory: relevance to electrophysiological studies of hippocampal function.Authorship 14226124Authorship 142424227110436Seetharaman S, Fleshner M, Park CR, Diamond DMBrain and behaviorSeetharaman S, Fleshner M, Park CR, Diamond DM. Influence of daily social stimulation on behavioral and physiological outcomes in an animal model of PTSD. Brain Behav. 2016 05; 6(5):e00458.Brain Behav2016-04-15T00:00:002016Influence of daily social stimulation on behavioral and physiological outcomes in an animal model of PTSD.27185913Reber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, F?chsl AM, Langgartner D, Walker FR, Hale MW, Lopez Perez G, Van Treuren W, Gonz?lez A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CAProceedings of the National Academy of Sciences of the United States of AmericaReber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, F?chsl AM, Langgartner D, Walker FR, Hale MW, Lopez Perez G, Van Treuren W, Gonz?lez A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CA. Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):E3130-9.Proc Natl Acad Sci U S A2016-05-16T00:00:002016Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice.Authorship 142841427124542Thompson RS, Roller R, Greenwood BN, Fleshner MStress (Amsterdam, Netherlands)Thompson RS, Roller R, Greenwood BN, Fleshner M. Wheel running improves REM sleep and attenuates stress-induced flattening of diurnal rhythms in F344 rats. Stress. 2016 05; 19(3):312-24.Stress2016-04-28T00:00:002016Wheel running improves REM sleep and attenuates stress-induced flattening of diurnal rhythms in F344 rats.9421133Fleshner M, Silbert L, Deak T, Goehler LE, Martin D, Watkins LR, Maier SFBrain research bulletinFleshner M, Silbert L, Deak T, Goehler LE, Martin D, Watkins LR, Maier SF. TNF-alpha-induced corticosterone elevation but not serum protein or corticosteroid binding globulin reduction is vagally mediated. Brain Res Bull. 1997; 44(6):701-6.Brain Res Bull1997-01-01T00:00:001997TNF-alpha-induced corticosterone elevation but not serum protein or corticosteroid binding globulin reduction is vagally mediated.9482808Nguyen KT, Deak T, Owens SM, Kohno T, Fleshner M, Watkins LR, Maier SFThe Journal of neuroscience : the official journal of the Society for NeuroscienceNguyen KT, Deak T, Owens SM, Kohno T, Fleshner M, Watkins LR, Maier SF. Exposure to acute stress induces brain interleukin-1beta protein in the rat. J Neurosci. 1998 Mar 15; 18(6):2239-46.J Neurosci1998-03-15T00:00:001998Exposure to acute stress induces brain interleukin-1beta protein in the rat.9663558Fleshner M, Goehler LE, Schwartz BA, McGorry M, Martin D, Maier SF, Watkins LRJournal of neuroimmunologyFleshner M, Goehler LE, Schwartz BA, McGorry M, Martin D, Maier SF, Watkins LR. Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy. J Neuroimmunol. 1998 Jun 15; 86(2):134-41.J Neuroimmunol1998-06-15T00:00:001998Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy.9728086Fleshner M, Nguyen KT, Cotter CS, Watkins LR, Maier SFThe American journal of physiologyFleshner M, Nguyen KT, Cotter CS, Watkins LR, Maier SF. Acute stressor exposure both suppresses acquired immunity and potentiates innate immunity. Am J Physiol. 1998 09; 275(3):R870-8.Am J Physiol1998-09-01T00:00:001998Acute stressor exposure both suppresses acquired immunity and potentiates innate immunity.9769157Pugh CR, Kumagawa K, Fleshner M, Watkins LR, Maier SF, Rudy JWBrain, behavior, and immunityPugh CR, Kumagawa K, Fleshner M, Watkins LR, Maier SF, Rudy JW. Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning. Brain Behav Immun. 1998 Sep; 12(3):212-29.Brain Behav Immun1998-09-01T00:00:001998Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning.10233137Noble EG, Moraska A, Mazzeo RS, Roth DA, Olsson MC, Moore RL, Fleshner MJournal of applied physiology (Bethesda, Md. : 1985)Noble EG, Moraska A, Mazzeo RS, Roth DA, Olsson MC, Moore RL, Fleshner M. Differential expression of stress proteins in rat myocardium after free wheel or treadmill run training. J Appl Physiol (1985). 1999 May; 86(5):1696-701.J Appl Physiol (1985)1999-05-01T00:00:001999Differential expression of stress proteins in rat myocardium after free wheel or treadmill run training.10595426Pugh CR, Nguyen KT, Gonyea JL, Fleshner M, Wakins LR, Maier SF, Rudy JWBehavioural brain researchPugh CR, Nguyen KT, Gonyea JL, Fleshner M, Wakins LR, Maier SF, Rudy JW. Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation. Behav Brain Res. 1999 Dec; 106(1-2):109-18.Behav Brain Res1999-12-01T00:00:001999Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation.Authorship 1469391127355182Grace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LRPainGrace PM, Fabisiak TJ, Green-Fulgham SM, Anderson ND, Strand KA, Kwilasz AJ, Galer EL, Walker FR, Greenwood BN, Maier SF, Fleshner M, Watkins LR. Prior voluntary wheel running attenuates neuropathic pain. Pain. 2016 09; 157(9):2012-23.Pain2016-09-01T00:00:002016Prior voluntary wheel running attenuates neuropathic pain.10575090Deak T, Nguyen KT, Cotter CS, Fleshner M, Watkins LR, Maier SF, Spencer RLBrain researchDeak T, Nguyen KT, Cotter CS, Fleshner M, Watkins LR, Maier SF, Spencer RL. Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor. Brain Res. 1999 Nov 20; 847(2):211-20.Brain Res1999-11-20T00:00:001999Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor.8516354Grisel JE, Fleshner M, Watkins LR, Maier SFPharmacology, biochemistry, and behaviorGrisel JE, Fleshner M, Watkins LR, Maier SF. Opioid and nonopioid interactions in two forms of stress-induced analgesia. Pharmacol Biochem Behav. 1993 May; 45(1):161-72.Pharmacol Biochem Behav1993-05-01T00:00:001993Opioid and nonopioid interactions in two forms of stress-induced analgesia.8577764Bennett MC, Mlady GW, Fleshner M, Rose GMProceedings of the National Academy of Sciences of the United States of AmericaBennett MC, Mlady GW, Fleshner M, Rose GM. Synergy between chronic corticosterone and sodium azide treatments in producing a spatial learning deficit and inhibiting cytochrome oxidase activity. Proc Natl Acad Sci U S A. 1996 Feb 06; 93(3):1330-4.Proc Natl Acad Sci U S A1996-02-06T00:00:001996Synergy between chronic corticosterone and sodium azide treatments in producing a spatial learning deficit and inhibiting cytochrome oxidase activity.10893019Fleshner MInternational journal of sports medicineFleshner M. Exercise and neuroendocrine regulation of antibody production: protective effect of physical activity on stress-induced suppression of the specific antibody response. Int J Sports Med. 2000 May; 21 Suppl 1:S14-9.Int J Sports Med2000-05-01T00:00:002000Exercise and neuroendocrine regulation of antibody production: protective effect of physical activity on stress-induced suppression of the specific antibody response.11448851Moraska A, Fleshner MAmerican journal of physiology. Regulatory, integrative and comparative physiologyMoraska A, Fleshner M. Voluntary physical activity prevents stress-induced behavioral depression and anti-KLH antibody suppression. Am J Physiol Regul Integr Comp Physiol. 2001 Aug; 281(2):R484-9.Am J Physiol Regul Integr Comp Physiol2001-08-01T00:00:002001Voluntary physical activity prevents stress-induced behavioral depression and anti-KLH antibody suppression.8945973Fleshner M, Brennan FX, Nguyen K, Watkins LR, Maier SFThe American journal of physiologyFleshner M, Brennan FX, Nguyen K, Watkins LR, Maier SF. RU-486 blocks differentially suppressive effect of stress on in vivo anti-KLH immunoglobulin response. Am J Physiol. 1996 Nov; 271(5 Pt 2):R1344-52.Am J Physiol1996-11-01T00:00:001996RU-486 blocks differentially suppressive effect of stress on in vivo anti-KLH immunoglobulin response.11457799Noteboom JT, Fleshner M, Enoka RMJournal of applied physiology (Bethesda, Md. : 1985)Noteboom JT, Fleshner M, Enoka RM. Activation of the arousal response can impair performance on a simple motor task. J Appl Physiol (1985). 2001 Aug; 91(2):821-31.J Appl Physiol (1985)2001-08-01T00:00:002001Activation of the arousal response can impair performance on a simple motor task.Authorship 151512827763700Mika A, Day HE, Martinez A, Rumian NL, Greenwood BN, Chichlowski M, Berg BM, Fleshner MThe European journal of neuroscienceMika A, Day HE, Martinez A, Rumian NL, Greenwood BN, Chichlowski M, Berg BM, Fleshner M. Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance. Eur J Neurosci. 2017 02; 45(3):342-357.Eur J Neurosci2016-11-12T00:00:002016Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance.9189266Fleshner M, Pugh CR, Tremblay D, Rudy JWBehavioral neuroscienceFleshner M, Pugh CR, Tremblay D, Rudy JW. DHEA-S selectively impairs contextual-fear conditioning: support for the antiglucocorticoid hypothesis. Behav Neurosci. 1997 Jun; 111(3):512-7.Behav Neurosci1997-06-01T00:00:001997DHEA-S selectively impairs contextual-fear conditioning: support for the antiglucocorticoid hypothesis.Authorship 152194427793217Mika A, Rumian N, Loughridge AB, Fleshner MInternational review of neurobiologyMika A, Rumian N, Loughridge AB, Fleshner M. Exercise and Prebiotics Produce Stress Resistance: Converging Impacts on Stress-Protective and Butyrate-Producing Gut Bacteria. Int Rev Neurobiol. 2016; 131:165-191.Int Rev Neurobiol2016-09-23T00:00:002016Exercise and Prebiotics Produce Stress Resistance: Converging Impacts on Stress-Protective and Butyrate-Producing Gut Bacteria.9435654Deak T, Meriwether JL, Fleshner M, Spencer RL, Abouhamze A, Moldawer LL, Grahn RE, Watkins LR, Maier SFThe American journal of physiologyDeak T, Meriwether JL, Fleshner M, Spencer RL, Abouhamze A, Moldawer LL, Grahn RE, Watkins LR, Maier SF. Evidence that brief stress may induce the acute phase response in rats. Am J Physiol. 1997 12; 273(6):R1998-2004.Am J Physiol1997-12-01T00:00:001997Evidence that brief stress may induce the acute phase response in rats.12651863Elphick GF, Wieseler-Frank J, Greenwood BN, Campisi J, Fleshner MJournal of applied physiology (Bethesda, Md. : 1985)Elphick GF, Wieseler-Frank J, Greenwood BN, Campisi J, Fleshner M. B-1 cell (CD5+/CD11b+) numbers and nIgM levels are elevated in physically active vs. sedentary rats. J Appl Physiol (1985). 2003 Jul; 95(1):199-206.J Appl Physiol (1985)2003-03-21T00:00:002003B-1 cell (CD5+/CD11b+) numbers and nIgM levels are elevated in physically active vs. sedentary rats.9629257Maier SF, Goehler LE, Fleshner M, Watkins LRAnnals of the New York Academy of SciencesMaier SF, Goehler LE, Fleshner M, Watkins LR. The role of the vagus nerve in cytokine-to-brain communication. Ann N Y Acad Sci. 1998 May 01; 840:289-300.Ann N Y Acad Sci1998-05-01T00:00:001998The role of the vagus nerve in cytokine-to-brain communication.Authorship 153967127412959Fleshner M, Frank M, Maier SFNeuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyFleshner M, Frank M, Maier SF. Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders. Neuropsychopharmacology. 2017 01; 42(1):36-45.Neuropsychopharmacology2016-07-14T00:00:002016Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders.Authorship 155556428077915Speaker KJ, Paton MM, Cox SS, Fleshner MMediators of inflammationSpeaker KJ, Paton MM, Cox SS, Fleshner M. A Single Bout of Fasting (24?h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats. Mediators Inflamm. 2016; 2016:1698071.Mediators Inflamm2016-12-18T00:00:002016A Single Bout of Fasting (24?h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats.12684476Greenwood BN, Foley TE, Day HE, Campisi J, Hammack SH, Campeau S, Maier SF, Fleshner MThe Journal of neuroscience : the official journal of the Society for NeuroscienceGreenwood BN, Foley TE, Day HE, Campisi J, Hammack SH, Campeau S, Maier SF, Fleshner M. Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. J Neurosci. 2003 Apr 01; 23(7):2889-98.J Neurosci2003-04-01T00:00:002003Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons.Authorship 1559706Authorship 156108828130174Lloyd BA, Hake HS, Ishiwata T, Farmer CE, Loetz EC, Fleshner M, Bland ST, Greenwood BNBehavioural brain researchLloyd BA, Hake HS, Ishiwata T, Farmer CE, Loetz EC, Fleshner M, Bland ST, Greenwood BN. Exercise increases mTOR signaling in brain regions involved in cognition and emotional behavior. Behav Brain Res. 2017 04 14; 323:56-67.Behav Brain Res2017-01-24T00:00:002017Exercise increases mTOR signaling in brain regions involved in cognition and emotional behavior.28119579Thompson RS, Roller R, Mika A, Greenwood BN, Knight R, Chichlowski M, Berg BM, Fleshner MFrontiers in behavioral neuroscienceThompson RS, Roller R, Mika A, Greenwood BN, Knight R, Chichlowski M, Berg BM, Fleshner M. Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. Front Behav Neurosci. 2016; 10:240.Front Behav Neurosci2017-01-10T00:00:002017Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity.12849759Greenwood BN, Kennedy S, Smith TP, Campeau S, Day HE, Fleshner MNeuroscienceGreenwood BN, Kennedy S, Smith TP, Campeau S, Day HE, Fleshner M. Voluntary freewheel running selectively modulates catecholamine content in peripheral tissue and c-Fos expression in the central sympathetic circuit following exposure to uncontrollable stress in rats. Neuroscience. 2003; 120(1):269-81.Neuroscience2003-01-01T00:00:002003Voluntary freewheel running selectively modulates catecholamine content in peripheral tissue and c-Fos expression in the central sympathetic circuit following exposure to uncontrollable stress in rats.12871965Campisi J, Hansen MK, O'Connor KA, Biedenkapp JC, Watkins LR, Maier SF, Fleshner MJournal of applied physiology (Bethesda, Md. : 1985)Campisi J, Hansen MK, O'Connor KA, Biedenkapp JC, Watkins LR, Maier SF, Fleshner M. Circulating cytokines and endotoxin are not necessary for the activation of the sickness or corticosterone response produced by peripheral E. coli challenge. J Appl Physiol (1985). 2003 Nov; 95(5):1873-82.J Appl Physiol (1985)2003-07-18T00:00:002003Circulating cytokines and endotoxin are not necessary for the activation of the sickness or corticosterone response produced by peripheral E. coli challenge.14557605Woodson JC, Macintosh D, Fleshner M, Diamond DMLearning & memory (Cold Spring Harbor, N.Y.)Woodson JC, Macintosh D, Fleshner M, Diamond DM. Emotion-induced amnesia in rats: working memory-specific impairment, corticosterone-memory correlation, and fear versus arousal effects on memory. Learn Mem. 2003 Sep-Oct; 10(5):326-36.Learn Mem2003-09-01T00:00:002003Emotion-induced amnesia in rats: working memory-specific impairment, corticosterone-memory correlation, and fear versus arousal effects on memory.14660058Gazda LS, Smith T, Watkins LR, Maier SF, Fleshner MStress (Amsterdam, Netherlands)Gazda LS, Smith T, Watkins LR, Maier SF, Fleshner M. Stressor exposure produces long-term reductions in antigen-specific T and B cell responses. Stress. 2003 Dec; 6(4):259-67.Stress2003-12-01T00:00:002003Stressor exposure produces long-term reductions in antigen-specific T and B cell responses.15220319Christou EA, Jakobi JM, Critchlow A, Fleshner M, Enoka RMJournal of applied physiology (Bethesda, Md. : 1985)Christou EA, Jakobi JM, Critchlow A, Fleshner M, Enoka RM. The 1- to 2-Hz oscillations in muscle force are exacerbated by stress, especially in older adults. J Appl Physiol (1985). 2004 Jul; 97(1):225-35.J Appl Physiol (1985)2004-07-01T00:00:002004The 1- to 2-Hz oscillations in muscle force are exacerbated by stress, especially in older adults.5Other Faculty1Professor15288392Holguin A, O'Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LRPainHolguin A, O'Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Pain. 2004 Aug; 110(3):517-530.Pain2004-08-01T00:00:002004HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS).2Assoc Professor4Instructor15944069Fleshner MBrain, behavior, and immunityFleshner M. Translational research using in vivo measures of primary antibody responses. Brain Behav Immun. 2005 Jul; 19(4):309-10.Brain Behav Immun2005-07-01T00:00:002005Translational research using in vivo measures of primary antibody responses.16048842Fleshner M, Johnson JDInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia GroupFleshner M, Johnson JD. Endogenous extra-cellular heat shock protein 72: releasing signal(s) and function. Int J Hyperthermia. 2005 Aug; 21(5):457-71.Int J Hyperthermia2005-08-01T00:00:002005Endogenous extra-cellular heat shock protein 72: releasing signal(s) and function.15632672Kennedy SL, Smith TP, Fleshner MMedicine and science in sports and exerciseKennedy SL, Smith TP, Fleshner M. Resting cellular and physiological effects of freewheel running. Med Sci Sports Exerc. 2005 Jan; 37(1):79-83.Med Sci Sports Exerc2005-01-01T00:00:002005Resting cellular and physiological effects of freewheel running.15737672Greenwood BN, Foley TE, Day HE, Burhans D, Brooks L, Campeau S, Fleshner MBiological psychiatryGreenwood BN, Foley TE, Day HE, Burhans D, Brooks L, Campeau S, Fleshner M. Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei. Biol Psychiatry. 2005 Mar 01; 57(5):559-68.Biol Psychiatry2005-03-01T00:00:002005Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei.2017-08-31NIHWATKINS, LINDA2011-09-01Preventing Transition of Acute-to-Chronic Neuropathic Pain: Models, Mechanisms &R01DE0219662004-11-30NIHFLESHNER, MONIKA R2000-12-15EXERCISE, STRESS AND IMMUNITY--PHYSIOLOGICAL MECHANISMSR01AI0485552000-06-30NIHFLESHNER, MONIKA R1999-07-01STRESS, EXERCISE AND INNATE IMMUNITYR03MH0603012010-05-31NIHFLESHNER, MONIKA R2004-06-01Stress, Heat-Shock Proteins, and Innate ImmunityR01AI0577972016-01-31NIHFLESHNER, MONIKA2003-06-01The Neurobiology of the Stress Resistant BrainR01MH0682832001-09-29NIHFLESHNER, MONIKA R1999-09-30EXERCISE PREVENTS THE IMMUNOSUPPRESSIVE EFFECT OF STRESSR03AI045576Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal InvestigatorCo-Principal Investigator16934883Foley TE, Greenwood BN, Day HE, Koch LG, Britton SL, Fleshner MBehavioural brain researchFoley TE, Greenwood BN, Day HE, Koch LG, Britton SL, Fleshner M. Elevated central monoamine receptor mRNA in rats bred for high endurance capacity: implications for central fatigue. Behav Brain Res. 2006 Nov 01; 174(1):132-42.Behav Brain Res2006-08-28T00:00:002006Elevated central monoamine receptor mRNA in rats bred for high endurance capacity: implications for central fatigue.17201074Smith TP, Kennedy SL, Smith M, Orent S, Fleshner MExercise immunology reviewSmith TP, Kennedy SL, Smith M, Orent S, Fleshner M. Physiological improvements and health benefits during an exercise-based comprehensive rehabilitation program in medically complex patients. Exerc Immunol Rev. 2006; 12:86-96.Exerc Immunol Rev2006-01-01T00:00:002006Physiological improvements and health benefits during an exercise-based comprehensive rehabilitation program in medically complex patients.17524614Frey DJ, Fleshner M, Wright KPBrain, behavior, and immunityFrey DJ, Fleshner M, Wright KP. The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults. Brain Behav Immun. 2007 Nov; 21(8):1050-7.Brain Behav Immun2007-05-23T00:00:002007The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults.17907830Greenwood BN, Strong PV, Dorey AA, Fleshner MBehavioral neuroscienceGreenwood BN, Strong PV, Dorey AA, Fleshner M. Therapeutic effects of exercise: wheel running reverses stress-induced interference with shuttle box escape. Behav Neurosci. 2007 Oct; 121(5):992-1000.Behav Neurosci2007-10-01T00:00:002007Therapeutic effects of exercise: wheel running reverses stress-induced interference with shuttle box escape.2271928Watkins LR, Thurston CL, Fleshner MBrain researchWatkins LR, Thurston CL, Fleshner M. Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases. Brain Res. 1990 Oct 01; 528(2):273-84.Brain Res1990-10-01T00:00:001990Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases.18300002Greenwood BN, Fleshner MNeuromolecular medicineGreenwood BN, Fleshner M. Exercise, learned helplessness, and the stress-resistant brain. Neuromolecular Med. 2008; 10(2):81-98.Neuromolecular Med2008-02-26T00:00:002008Exercise, learned helplessness, and the stress-resistant brain.18574787Zoladz PR, Conrad CD, Fleshner M, Diamond DMStress (Amsterdam, Netherlands)Zoladz PR, Conrad CD, Fleshner M, Diamond DM. Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder. Stress. 2008 Jul; 11(4):259-81.Stress2008-07-01T00:00:002008Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder.18648634Park CR, Campbell AM, Woodson JC, Smith TP, Fleshner M, Diamond DMDose-response : a publication of International Hormesis SocietyPark CR, Campbell AM, Woodson JC, Smith TP, Fleshner M, Diamond DM. Permissive influence of stress in the expression of a U-shaped relationship between serum corticosterone levels and spatial memory errors in rats. Dose Response. 2006 Jun 20; 4(1):55-74.Dose Response2006-06-20T00:00:002006Permissive influence of stress in the expression of a U-shaped relationship between serum corticosterone levels and spatial memory errors in rats.19587852Zoladz PR, Park CR, Mu?oz C, Fleshner M, Diamond DMCurrent neuropharmacologyZoladz PR, Park CR, Mu?oz C, Fleshner M, Diamond DM. Tianeptine: an antidepressant with memory-protective properties. Curr Neuropharmacol. 2008 Dec; 6(4):311-21.Curr Neuropharmacol2008-12-01T00:00:002008Tianeptine: an antidepressant with memory-protective properties.20138850Campeau S, Nyhuis TJ, Kryskow EM, Masini CV, Babb JA, Sasse SK, Greenwood BN, Fleshner M, Day HEBrain researchCampeau S, Nyhuis TJ, Kryskow EM, Masini CV, Babb JA, Sasse SK, Greenwood BN, Fleshner M, Day HE. Stress rapidly increases alpha 1d adrenergic receptor mRNA in the rat dentate gyrus. Brain Res. 2010 Apr 06; 1323:109-18.Brain Res2010-02-06T00:00:002010Stress rapidly increases alpha 1d adrenergic receptor mRNA in the rat dentate gyrus.10407060Mesches MH, Fleshner M, Heman KL, Rose GM, Diamond DMThe Journal of neuroscience : the official journal of the Society for NeuroscienceMesches MH, Fleshner M, Heman KL, Rose GM, Diamond DM. Exposing rats to a predator blocks primed burst potentiation in the hippocampus in vitro. J Neurosci. 1999 Jul 15; 19(14):RC18.J Neurosci1999-07-15T00:00:001999Exposing rats to a predator blocks primed burst potentiation in the hippocampus in vitro.10474053Deak T, Nguyen KT, Fleshner M, Watkins LR, Maier SFNeuroimmunomodulationDeak T, Nguyen KT, Fleshner M, Watkins LR, Maier SF. Acute stress may facilitate recovery from a subcutaneous bacterial challenge. Neuroimmunomodulation. 1999 Sep-Oct; 6(5):344-54.Neuroimmunomodulation1999-09-01T00:00:001999Acute stress may facilitate recovery from a subcutaneous bacterial challenge.Authorship 168203128838855Fleshner M, Crane CRTrends in immunologyFleshner M, Crane CR. Exosomes, DAMPs and miRNA: Features of Stress Physiology and Immune Homeostasis. Trends Immunol. 2017 10; 38(10):768-776.Trends Immunol2017-08-23T00:00:002017Exosomes, DAMPs and miRNA: Features of Stress Physiology and Immune Homeostasis.21168480Fleshner MBrain, behavior, and immunityFleshner M. The gut microbiota: a new player in the innate immune stress response? Brain Behav Immun. 2011 Mar; 25(3):395-6.Brain Behav Immun2010-12-17T00:00:002010The gut microbiota: a new player in the innate immune stress response?21446352Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon PExercise immunology reviewWalsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011; 17:6-63.Exerc Immunol Rev2011-01-01T00:00:002011Position statement. Part one: Immune function and exercise.11105778Colagiovanni DB, Suniga MA, Frazier JL, Edwards CK, Fleshner M, McCay JA, White KL, Shopp GMImmunopharmacology and immunotoxicologyColagiovanni DB, Suniga MA, Frazier JL, Edwards CK, Fleshner M, McCay JA, White KL, Shopp GM. TNF-alpha blockade by a dimeric TNF type I receptor molecule selectively inhibits adaptive immune responses. Immunopharmacol Immunotoxicol. 2000 Nov; 22(4):627-51.Immunopharmacol Immunotoxicol2000-11-01T00:00:002000TNF-alpha blockade by a dimeric TNF type I receptor molecule selectively inhibits adaptive immune responses.21538655Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DMHippocampusZoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. 2012 Mar; 22(3):577-89.Hippocampus2011-05-02T00:00:002011Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia.11166076Rachal Pugh C, Fleshner M, Watkins LR, Maier SF, Rudy JWNeuroscience and biobehavioral reviewsRachal Pugh C, Fleshner M, Watkins LR, Maier SF, Rudy JW. The immune system and memory consolidation: a role for the cytokine IL-1beta. Neurosci Biobehav Rev. 2001 Jan; 25(1):29-41.Neurosci Biobehav Rev2001-01-01T00:00:002001The immune system and memory consolidation: a role for the cytokine IL-1beta.11189018Hansen MK, Nguyen KT, Goehler LE, Gaykema RP, Fleshner M, Maier SF, Watkins LRAutonomic neuroscience : basic & clinicalHansen MK, Nguyen KT, Goehler LE, Gaykema RP, Fleshner M, Maier SF, Watkins LR. Effects of vagotomy on lipopolysaccharide-induced brain interleukin-1beta protein in rats. Auton Neurosci. 2000 Dec 20; 85(1-3):119-26.Auton Neurosci2000-12-20T00:00:002000Effects of vagotomy on lipopolysaccharide-induced brain interleukin-1beta protein in rats.11238624Fleshner M, Deak T, Nguyen KT, Watkins LR, Maier SFJournal of immunology (Baltimore, Md. : 1950)Fleshner M, Deak T, Nguyen KT, Watkins LR, Maier SF. Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response. J Immunol. 2001 Mar 15; 166(6):3813-9.J Immunol2001-03-15T00:00:002001Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.21907418Hains LE, Loram LC, Taylor FR, Strand KA, Wieseler JL, Barrientos RM, Young JJ, Frank MG, Sobesky J, Martin TJ, Eisenach JC, Maier SF, Johnson JD, Fleshner M, Watkins LRJournal of neuroimmunologyHains LE, Loram LC, Taylor FR, Strand KA, Wieseler JL, Barrientos RM, Young JJ, Frank MG, Sobesky J, Martin TJ, Eisenach JC, Maier SF, Johnson JD, Fleshner M, Watkins LR. Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. J Neuroimmunol. 2011 Oct 28; 239(1-2):53-60.J Neuroimmunol2011-09-09T00:00:002011Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors.2752305Diamond DM, Bennett MC, Engstrom DA, Fleshner M, Rose GMBrain researchDiamond DM, Bennett MC, Engstrom DA, Fleshner M, Rose GM. Adrenalectomy reduces the threshold for hippocampal primed burst potentiation in the anesthetized rat. Brain Res. 1989 Jul 17; 492(1-2):356-60.Brain Res1989-07-17T00:00:001989Adrenalectomy reduces the threshold for hippocampal primed burst potentiation in the anesthetized rat.22769435Saludes JP, Morton LA, Ghosh N, Beninson LA, Chapman ER, Fleshner M, Yin HACS chemical biologySaludes JP, Morton LA, Ghosh N, Beninson LA, Chapman ER, Fleshner M, Yin H. Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. ACS Chem Biol. 2012 Oct 19; 7(10):1629-35.ACS Chem Biol2012-07-17T00:00:002012Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I.2813542Fleshner M, Laudenslager ML, Simons L, Maier SFPhysiology & behaviorFleshner M, Laudenslager ML, Simons L, Maier SF. Reduced serum antibodies associated with social defeat in rats. Physiol Behav. 1989 Jun; 45(6):1183-7.Physiol Behav1989-06-01T00:00:001989Reduced serum antibodies associated with social defeat in rats.22895704Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LRThe Journal of neuroscience : the official journal of the Society for NeuroscienceHutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. J Neurosci. 2012 Aug 15; 32(33):11187-200.J Neurosci2012-08-15T00:00:002012Opioid activation of toll-like receptor 4 contributes to drug reinforcement.23049953Greenwood BN, Strong PV, Loughridge AB, Day HE, Clark PJ, Mika A, Hellwinkel JE, Spence KG, Fleshner MPloS oneGreenwood BN, Strong PV, Loughridge AB, Day HE, Clark PJ, Mika A, Hellwinkel JE, Spence KG, Fleshner M. 5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. PLoS One. 2012; 7(9):e46118.PLoS One2012-09-25T00:00:0020125-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise.23103443Maslanik T, Mahaffey L, Tannura K, Beninson L, Greenwood BN, Fleshner MBrain, behavior, and immunityMaslanik T, Mahaffey L, Tannura K, Beninson L, Greenwood BN, Fleshner M. The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure. Brain Behav Immun. 2013 Feb; 28:54-62.Brain Behav Immun2012-10-24T00:00:002012The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure.23236381Maslanik T, Tannura K, Mahaffey L, Loughridge AB, Beninson L, Benninson L, Ursell L, Greenwood BN, Knight R, Fleshner MPloS oneMaslanik T, Tannura K, Mahaffey L, Loughridge AB, Beninson L, Benninson L, Ursell L, Greenwood BN, Knight R, Fleshner M. Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1? and IL-18 but not IL-6, IL-10 or MCP-1. PLoS One. 2012; 7(12):e50636.PLoS One2012-12-07T00:00:002012Commensal bacteria and MAMPs are necessary for stress-induced increases in IL-1? and IL-18 but not IL-6, IL-10 or MCP-1.23318688Zoladz PR, Fleshner M, Diamond DMProgress in neuro-psychopharmacology & biological psychiatryZoladz PR, Fleshner M, Diamond DM. Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 01; 44:1-16.Prog Neuropsychopharmacol Biol Psychiatry2013-01-12T00:00:002013Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD.23454291Thompson RS, Christianson JP, Maslanik TM, Maier SF, Greenwood BN, Fleshner MPhysiology & behaviorThompson RS, Christianson JP, Maslanik TM, Maier SF, Greenwood BN, Fleshner M. Effects of stressor controllability on diurnal physiological rhythms. Physiol Behav. 2013 Mar 15; 112-113:32-9.Physiol Behav2013-02-27T00:00:002013Effects of stressor controllability on diurnal physiological rhythms.7549034Fleshner M, Hermann J, Lockwood LL, Laudenslager ML, Watkins LR, Maier SFBrain, behavior, and immunityFleshner M, Hermann J, Lockwood LL, Laudenslager ML, Watkins LR, Maier SF. Stressed rats fail to expand the CD45RC+CD4+ (Th1-like) T cell subset in response to KLH: possible involvement of IFN-gamma. Brain Behav Immun. 1995 Jun; 9(2):101-12.Brain Behav Immun1995-06-01T00:00:001995Stressed rats fail to expand the CD45RC+CD4+ (Th1-like) T cell subset in response to KLH: possible involvement of IFN-gamma.1308198Diamond DM, Bennett MC, Fleshner M, Rose GMHippocampusDiamond DM, Bennett MC, Fleshner M, Rose GM. Inverted-U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation. Hippocampus. 1992 Oct; 2(4):421-30.Hippocampus1992-10-01T00:00:001992Inverted-U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation.14686090Fleshner M, Campisi J, Johnson JDExercise immunology reviewFleshner M, Campisi J, Johnson JD. Can exercise stress facilitate innate immunity? A functional role for stress-induced extracellular Hsp72. Exerc Immunol Rev. 2003; 9:6-24.Exerc Immunol Rev2003-01-01T00:00:002003Can exercise stress facilitate innate immunity? A functional role for stress-induced extracellular Hsp72.14984061Campisi J, Leem TH, Fleshner MCell stress & chaperonesCampisi J, Leem TH, Fleshner M. Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system. Cell Stress Chaperones. 2003; 8(3):272-86.Cell Stress Chaperones2003-01-01T00:00:002003Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system.15247195Smith TP, Kennedy SL, Fleshner MJournal of applied physiology (Bethesda, Md. : 1985)Smith TP, Kennedy SL, Fleshner M. Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men. J Appl Physiol (1985). 2004 Aug; 97(2):491-8.J Appl Physiol (1985)2004-08-01T00:00:002004Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men.8295955Fleshner M, Brohm MM, Laudenslager ML, Watkins LR, Maier SFPhysiology & behaviorFleshner M, Brohm MM, Laudenslager ML, Watkins LR, Maier SF. Modulation of the in vivo antibody response by a benzodiazepine inverse agonist (DMCM) administered centrally or peripherally. Physiol Behav. 1993 Dec; 54(6):1149-54.Physiol Behav1993-12-01T00:00:001993Modulation of the in vivo antibody response by a benzodiazepine inverse agonist (DMCM) administered centrally or peripherally.8315162Thomas-Dobersen DA, Butler-Simon N, Fleshner MJournal of the American Dietetic AssociationThomas-Dobersen DA, Butler-Simon N, Fleshner M. Evaluation of a weight management intervention program in adolescents with insulin-dependent diabetes mellitus. J Am Diet Assoc. 1993 May; 93(5):535-40.J Am Diet Assoc1993-05-01T00:00:001993Evaluation of a weight management intervention program in adolescents with insulin-dependent diabetes mellitus.8637401Brennan FX, Fleshner M, Watkins LR, Maier SFLife sciencesBrennan FX, Fleshner M, Watkins LR, Maier SF. Macrophage stimulation reduces the cholesterol levels of stressed and unstressed rats. Life Sci. 1996; 58(20):1771-6.Life Sci1996-01-01T00:00:001996Macrophage stimulation reduces the cholesterol levels of stressed and unstressed rats.8768720Lockwood LL, Silbert LH, Fleshner MR, McNeal C, Watkins LR, Laudenslager ML, Rice KC, Weber RJ, Maier SFThe Journal of pharmacology and experimental therapeuticsLockwood LL, Silbert LH, Fleshner MR, McNeal C, Watkins LR, Laudenslager ML, Rice KC, Weber RJ, Maier SF. Morphine-induced alterations in antibody levels: receptor and immune mechanisms. J Pharmacol Exp Ther. 1996 Aug; 278(2):689-96.J Pharmacol Exp Ther1996-08-01T00:00:001996Morphine-induced alterations in antibody levels: receptor and immune mechanisms.8848267Diamond DM, Branch BJ, Fleshner MNeuroscience lettersDiamond DM, Branch BJ, Fleshner M. The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term, potentiation. Neurosci Lett. 1996 Jan 05; 202(3):204-8.Neurosci Lett1996-01-05T00:00:001996The neurosteroid dehydroepiandrosterone sulfate (DHEAS) enhances hippocampal primed burst, but not long-term, potentiation.9013504Pugh CR, Fleshner M, Rudy JWNeurobiology of learning and memoryPugh CR, Fleshner M, Rudy JW. Type II glucocorticoid receptor antagonists impair contextual but not auditory-cue fear conditioning in juvenile rats. Neurobiol Learn Mem. 1997 Jan; 67(1):75-9.Neurobiol Learn Mem1997-01-01T00:00:001997Type II glucocorticoid receptor antagonists impair contextual but not auditory-cue fear conditioning in juvenile rats.9189265Pugh CR, Tremblay D, Fleshner M, Rudy JWBehavioral neurosciencePugh CR, Tremblay D, Fleshner M, Rudy JW. A selective role for corticosterone in contextual-fear conditioning. Behav Neurosci. 1997 Jun; 111(3):503-11.Behav Neurosci1997-06-01T00:00:001997A selective role for corticosterone in contextual-fear conditioning.9359608Milligan ED, McGorry MM, Fleshner M, Gaykema RP, Goehler LE, Watkins LR, Maier SFBrain researchMilligan ED, McGorry MM, Fleshner M, Gaykema RP, Goehler LE, Watkins LR, Maier SF. Subdiaphragmatic vagotomy does not prevent fever following intracerebroventricular prostaglandin E2: further evidence for the importance of vagal afferents in immune-to-brain communication. Brain Res. 1997 Aug 22; 766(1-2):240-3.Brain Res1997-08-22T00:00:001997Subdiaphragmatic vagotomy does not prevent fever following intracerebroventricular prostaglandin E2: further evidence for the importance of vagal afferents in immune-to-brain communication.15978673Kennedy SL, Nickerson M, Campisi J, Johnson JD, Smith TP, Sharkey C, Fleshner MJournal of neuroimmunologyKennedy SL, Nickerson M, Campisi J, Johnson JD, Smith TP, Sharkey C, Fleshner M. Splenic norepinephrine depletion following acute stress suppresses in vivo antibody response. J Neuroimmunol. 2005 Aug; 165(1-2):150-60.J Neuroimmunol2005-08-01T00:00:002005Splenic norepinephrine depletion following acute stress suppresses in vivo antibody response.1469075Fleshner M, Watkins LR, Lockwood LL, Bellgrau D, Laudenslager ML, Maier SFJournal of neuroimmunologyFleshner M, Watkins LR, Lockwood LL, Bellgrau D, Laudenslager ML, Maier SF. Specific changes in lymphocyte subpopulations: a potential mechanism for stress-induced immunomodulation. J Neuroimmunol. 1992 Dec; 41(2):131-42.J Neuroimmunol1992-12-01T00:00:001992Specific changes in lymphocyte subpopulations: a potential mechanism for stress-induced immunomodulation.2002883Barnes CA, Forster MJ, Fleshner M, Ahanotu EN, Laudenslager ML, Mazzeo RS, Maier SF, Lal HNeurobiology of agingBarnes CA, Forster MJ, Fleshner M, Ahanotu EN, Laudenslager ML, Mazzeo RS, Maier SF, Lal H. Exercise does not modify spatial memory, brain autoimmunity, or antibody response in aged F-344 rats. Neurobiol Aging. 1991 Jan-Feb; 12(1):47-53.Neurobiol Aging1991-01-01T00:00:001991Exercise does not modify spatial memory, brain autoimmunity, or antibody response in aged F-344 rats.16081876Nickerson M, Elphick GF, Campisi J, Greenwood BN, Fleshner MAmerican journal of physiology. Regulatory, integrative and comparative physiologyNickerson M, Elphick GF, Campisi J, Greenwood BN, Fleshner M. Physical activity alters the brain Hsp72 and IL-1beta responses to peripheral E. coli challenge. 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Mol Biosyst. 2013 Aug; 9(8):2005-9.Mol Biosyst2013-05-28T00:00:002013Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles.D011916Living Beings782450.941038Rats, Inbred F344D013312Physiology1924330.754167Stress, Physiological1725 Pleasant St.1CLREClare Small Arts & Sci Bldg1725 Pleasant St.Boulder80309-0001COD051381Living Beings84254260.52472RatsD013315Concepts & IdeasDisorders32410210.540294Stress, PsychologicalAuthorship 100791Authorship 200266731070769Sprecher KE, Ritchie HK, Burke TM, Depner CM, Smits AN, Dorrestein PC, Fleshner M, Knight R, Lowry CA, Turek FW, Vitaterna MH, Wright KPSleepSprecher KE, Ritchie HK, Burke TM, Depner CM, Smits AN, Dorrestein PC, Fleshner M, Knight R, Lowry CA, Turek FW, Vitaterna MH, Wright KP. Trait-like vulnerability of higher-order cognition and ability to maintain wakefulness during combined sleep restriction and circadian misalignment. Sleep. 2019 08 01; 42(8).Sleep2019-08-01T00:00:002019Trait-like vulnerability of higher-order cognition and ability to maintain wakefulness during combined sleep restriction and circadian misalignment.Authorship 102175Authorship 104843CLAS-PsychologyIntegrative PhysiologyPsych-PsychologySOM-MEDInfectious DiseaseUniversity of Colorado BoulderUniversity of Colorado Denver - Anschutz Medical CampusUniversity of Colorado Denver - Denver CampusRobertSpencerRobert L Spencer40.00869130000000-105.268983300000001039Spencer, RobertProfessorRussellMooreRussell Moore40.00943840000000-105.270389600000001320Moore, RussellProfessorStevenHobbsSteven L Hobbs40.00943840000000-105.270389600000001287Hobbs, StevenSenior InstructorLeifSaulLeif J Saul40.00943840000000-105.27038960000000158Saul, LeifSenior InstructorTeresaFoleyTeresa E. Foley40.00943840000000-105.270389600000001626Foley, TeresaFaculty FellowCharlesDinarelloCharles A Dinarello39.74528180000000-104.8375727000000023Dinarello, CharlesDistinguished ProfessorBenjaminGreenwoodBenjamin N Greenwood39.74519020000000-105.00213520000000256Greenwood, BenjaminAssociate ProfessorJiaShiJia Shi40.00943840000000-105.270389600000002523Shi, JiaSenior InstructorChristopherLowryChristopher Lowry40.00943840000000-105.270389600000002814Lowry, ChristopherProfessor8.109550.00521769681research areas9.160120.016054828coauthor of188.73421.948460similar to11188selected publicationsLindaWatkinsLinda R Watkins40.00869130000000-105.26898330000000365Watkins, LindaDistinguished ProfessorAuthorship 115521HeidiDayHeidi E W Day40.00869130000000-105.26898330000000579Day, HeidiAssoc ChairAuthorship 117385Authorship 208479531525404Arnold MR, Greenwood BN, McArthur JA, Clark PJ, Fleshner M, Lowry CABehavioural brain researchArnold MR, Greenwood BN, McArthur JA, Clark PJ, Fleshner M, Lowry CA. Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats. Behav Brain Res. 2020 01 27; 378:112237.Behav Brain Res2019-09-13T00:00:002019Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats.Authorship 209721131593301Fleshner MThe European journal of neuroscienceFleshner M. Bidirectional gut-microbial?mediated-brain signaling: A new player in stress physiology? (Commentary on O'Mahony et al., 2019). Eur J Neurosci. 2020 09; 52(5):3487-3489.Eur J Neurosci2019-10-29T00:00:002019Bidirectional gut-microbial?mediated-brain signaling: A new player in stress physiology? (Commentary on O'Mahony et al., 2019).Authorship 128612Authorship 135671Authorship 146101Authorship 147263Authorship 2163391032078624Bowers SJ, Vargas F, Gonz?lez A, He S, Jiang P, Dorrestein PC, Knight R, Wright KP, Lowry CA, Fleshner M, Vitaterna MH, Turek FWPloS oneBowers SJ, Vargas F, Gonz?lez A, He S, Jiang P, Dorrestein PC, Knight R, Wright KP, Lowry CA, Fleshner M, Vitaterna MH, Turek FW. Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome. PLoS One. 2020; 15(2):e0229001.PLoS One2020-02-20T00:00:002020Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome.Authorship 217204632123201Thompson RS, Vargas F, Dorrestein PC, Chichlowski M, Berg BM, Fleshner MScientific reportsThompson RS, Vargas F, Dorrestein PC, Chichlowski M, Berg BM, Fleshner M. Dietary prebiotics alter novel microbial dependent fecal metabolites that improve sleep. Sci Rep. 2020 03 02; 10(1):3848.Sci Rep2020-03-02T00:00:002020Dietary prebiotics alter novel microbial dependent fecal metabolites that improve sleep.Authorship 224869232766411Greenwood BN, Fleshner MCurrent opinion in behavioral sciencesGreenwood BN, Fleshner M. Voluntary Wheel Running: A Useful Rodent Model for Investigating the Mechanisms of Stress Robustness and Neural Circuits of Exercise Motivation. Curr Opin Behav Sci. 2019 Aug; 28:78-84.Curr Opin Behav Sci2019-03-13T00:00:002019Voluntary Wheel Running: A Useful Rodent Model for Investigating the Mechanisms of Stress Robustness and Neural Circuits of Exercise Motivation.Authorship 160613Authorship 161413Authorship 231811533283862Bowers SJ, Lambert S, He S, Lowry CA, Fleshner M, Wright KP, Turek FW, Vitaterna MHSleepBowers SJ, Lambert S, He S, Lowry CA, Fleshner M, Wright KP, Turek FW, Vitaterna MH. Immunization with a heat-killed bacterium, Mycobacterium vaccae NCTC 11659, prevents the development of cortical hyperarousal and a PTSD-like sleep phenotype after sleep disruption and acute stress in mice. Sleep. 2021 06 11; 44(6).Sleep2021-06-11T00:00:002021Immunization with a heat-killed bacterium, Mycobacterium vaccae NCTC 11659, prevents the development of cortical hyperarousal and a PTSD-like sleep phenotype after sleep disruption and acute stress in mice.Authorship 2340901Authorship 2346943533444730Fleshner MBrain, behavior, and immunityFleshner M. Mentorship Memoriam: Mark Laudenslager, PhD. Brain Behav Immun. 2021 05; 94:18.Brain Behav Immun2021-01-11T00:00:002021Mentorship Memoriam: Mark Laudenslager, PhD.33469429Foxx CL, Heinze JD, Gonz?lez A, Vargas F, Baratta MV, Elsayed AI, Stewart JR, Loupy KM, Arnold MR, Flux MC, Sago SA, Siebler PH, Milton LN, Lieb MW, Hassell JE, Smith DG, Lee KAK, Appiah SA, Schaefer EJ, Panitchpakdi M, Sikora NC, Weldon KC, Stamper CE, Schmidt D, Duggan DA, Mengesha YM, Ogbaselassie M, Nguyen KT, Gates CA, Schnabel K, Tran L, Jones JD, Vitaterna MH, Turek FW, Fleshner M, Dorrestein PC, Knight R, Wright KP, Lowry CAFrontiers in physiologyFoxx CL, Heinze JD, Gonz?lez A, Vargas F, Baratta MV, Elsayed AI, Stewart JR, Loupy KM, Arnold MR, Flux MC, Sago SA, Siebler PH, Milton LN, Lieb MW, Hassell JE, Smith DG, Lee KAK, Appiah SA, Schaefer EJ, Panitchpakdi M, Sikora NC, Weldon KC, Stamper CE, Schmidt D, Duggan DA, Mengesha YM, Ogbaselassie M, Nguyen KT, Gates CA, Schnabel K, Tran L, Jones JD, Vitaterna MH, Turek FW, Fleshner M, Dorrestein PC, Knight R, Wright KP, Lowry CA. Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a "Two Hit" Stressor Model. Front Physiol. 2020; 11:524833.Front Physiol2021-01-05T00:00:002021Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a "Two Hit" Stressor Model.Authorship 173793Authorship 242360134131360Fleshner M, Epperson N, Dantzer RPsychoneuroendocrinologyFleshner M, Epperson N, Dantzer R. Those we have lost: Dr. Mark L. Laudenslager. Psychoneuroendocrinology. 2021 02; 124:105126.Psychoneuroendocrinology2020-12-31T00:00:002020Those we have lost: Dr. Mark L. Laudenslager.Authorship 2431451534242738Thompson RS, Gaffney M, Hopkins S, Kelley T, Gonzalez A, Bowers SJ, Vitaterna MH, Turek FW, Foxx CL, Lowry CA, Vargas F, Dorrestein PC, Wright KP, Knight R, Fleshner MBrain, behavior, and immunityThompson RS, Gaffney M, Hopkins S, Kelley T, Gonzalez A, Bowers SJ, Vitaterna MH, Turek FW, Foxx CL, Lowry CA, Vargas F, Dorrestein PC, Wright KP, Knight R, Fleshner M. Ruminiclostridium 5, Parabacteroides distasonis, and bile acid profile are modulated by prebiotic diet and associate with facilitated sleep/clock realignment after chronic disruption of rhythms. Brain Behav Immun. 2021 10; 97:150-166.Brain Behav Immun2021-07-07T00:00:002021Ruminiclostridium 5, Parabacteroides distasonis, and bile acid profile are modulated by prebiotic diet and associate with facilitated sleep/clock realignment after chronic disruption of rhythms.Authorship 187795Authorship 253845734915155Frank MG, Nguyen KH, Ball JB, Hopkins S, Kelley T, Baratta MV, Fleshner M, Maier SFBrain, behavior, and immunityFrank MG, Nguyen KH, Ball JB, Hopkins S, Kelley T, Baratta MV, Fleshner M, Maier SF. SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties. Brain Behav Immun. 2022 02; 100:267-277.Brain Behav Immun2021-12-13T00:00:002021SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties.Authorship 190662Authorship 195173Authorship 2634841235685770Bowers SJ, Summa KC, Thompson RS, Gonz?lez A, Vargas F, Olker C, Jiang P, Lowry CA, Dorrestein PC, Knight R, Wright KP, Fleshner M, Turek FW, Vitaterna MHFrontiers in neuroscienceBowers SJ, Summa KC, Thompson RS, Gonz?lez A, Vargas F, Olker C, Jiang P, Lowry CA, Dorrestein PC, Knight R, Wright KP, Fleshner M, Turek FW, Vitaterna MH. A Prebiotic Diet Alters the Fecal Microbiome and Improves Sleep in Response to Sleep Disruption in Rats. Front Neurosci. 2022; 16:889211.Front Neurosci2022-05-24T00:00:002022A Prebiotic Diet Alters the Fecal Microbiome and Improves Sleep in Response to Sleep Disruption in Rats.Authorship 214116Authorship 214287Authorship 222222Authorship 232216Authorship 234057Authorship 235601Authorship 256491Authorship 25746837116592Frank MG, Fleshner M, Maier SFBrain, behavior, and immunityFrank MG, Fleshner M, Maier SF. Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP:TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of COVID-19. Brain Behav Immun. 2023 07; 111:259-269.Brain Behav Immun2023-04-27T00:00:002023Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP:TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of COVID-19.Authorship 2818032Authorship 265395Authorship 2833557Authorship 284276637275221Hopkins S, Kelley T, Roller R, Thompson RS, Colagiovanni DB, Chupka K, Fleshner MFrontiers in physiologyHopkins S, Kelley T, Roller R, Thompson RS, Colagiovanni DB, Chupka K, Fleshner M. Oral CBD-rich hemp extract modulates sterile inflammation in female and male rats. Front Physiol. 2023; 14:1112906.Front Physiol2023-05-18T00:00:002023Oral CBD-rich hemp extract modulates sterile inflammation in female and male rats.37273279Buhr TJ, Reed CH, Wee OM, Lee JH, Yuan LL, Fleshner M, Valentine RJ, Clark PJFrontiers in behavioral neuroscienceBuhr TJ, Reed CH, Wee OM, Lee JH, Yuan LL, Fleshner M, Valentine RJ, Clark PJ. The persistence of stress-induced physical inactivity in rats: an investigation of central monoamine neurotransmitters and skeletal muscle oxidative stress. Front Behav Neurosci. 2023; 17:1169151.Front Behav Neurosci2023-05-16T00:00:002023The persistence of stress-induced physical inactivity in rats: an investigation of central monoamine neurotransmitters and skeletal muscle oxidative stress.Authorship 266112RobertThompsonRobert S Thompson40.00943840000000-105.270389600000008243Thompson, RobertResearch Associatetrue1Distinguished ProfessorDistinguished ProfessorAuthorship 279054Authorship 279354Authorship 279502Authorship 287492Authorship 293871Authorship 303207Authorship 308917Authorship 309081Authorship 311591Authorship 316831Authorship 319246Authorship 322163Authorship 332219true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Research AssociateResearch Associatetrue1Senior InstructorSenior Instructortrue1Senior InstructorSenior Instructortrue1Associate ProfessorAssociate Professortrue1Assoc ChairAssoc Chairtrue1Faculty FellowFaculty Fellowtrue1Senior InstructorSenior Instructortrue1Distinguished ProfessorDistinguished ProfessorAuthorship 351847Authorship 355093Authorship 358502Authorship 361097Authorship 362743Authorship 369662Authorship 370296Authorship 378413Authorship 383265Authorship 395717Authorship 406631Authorship 407667Authorship 409254Authorship 409685Authorship 415503Authorship 431325Authorship 438227Authorship 438701Authorship 107622624321216Cox SS, Speaker KJ, Beninson LA, Craig WC, Paton MM, Fleshner MBrain, behavior, and immunityCox SS, Speaker KJ, Beninson LA, Craig WC, Paton MM, Fleshner M. Adrenergic and glucocorticoid modulation of the sterile inflammatory response. Brain Behav Immun. 2014 Feb; 36:183-92.Brain Behav Immun2013-12-07T00:00:002013Adrenergic and glucocorticoid modulation of the sterile inflammatory response.Authorship 4509910Authorship 464003Authorship 475656Authorship 48145Authorship 488143Authorship 494599Authorship 109970724447583Thompson RS, Strong PV, Clark PJ, Maslanik TM, Wright KP, Greenwood BN, Fleshner MActa physiologica (Oxford, England)Thompson RS, Strong PV, Clark PJ, Maslanik TM, Wright KP, Greenwood BN, Fleshner M. Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats. Acta Physiol (Oxf). 2014 Jun; 211(2):447-65.Acta Physiol (Oxf)2014-02-25T00:00:002014Repeated fear-induced diurnal rhythm disruptions predict PTSD-like sensitized physiological acute stress responses in F344 rats.Authorship 508562Authorship 511511Authorship 512031Authorship 516205Authorship 517295Authorship 522252Authorship 523072Authorship 531073Authorship 532373Authorship 533974Authorship 535453Authorship 535905Authorship 111693724246250Speaker KJ, Cox SS, Paton MM, Serebrakian A, Maslanik T, Greenwood BN, Fleshner MBrain, behavior, and immunitySpeaker KJ, Cox SS, Paton MM, Serebrakian A, Maslanik T, Greenwood BN, Fleshner M. Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of lean rats. Brain Behav Immun. 2014 Jul; 39:87-98.Brain Behav Immun2013-11-15T00:00:002013Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of lean rats.Authorship 536771Authorship 53856Authorship 545692Authorship 546993Authorship 557281Authorship 55853Authorship 569534Authorship 591345Authorship 594762Authorship 598533Authorship 607624Authorship 610664Authorship 617893Authorship 620543Authorship 621985Authorship 627847Authorship 629093Authorship 633363Authorship 634772Authorship 6385110Authorship 6513Authorship 66334Authorship 667032Authorship 667682Authorship 114597725017571Clark PJ, Ghasem PR, Mika A, Day HE, Herrera JJ, Greenwood BN, Fleshner MBehavioural brain researchClark PJ, Ghasem PR, Mika A, Day HE, Herrera JJ, Greenwood BN, Fleshner M. Wheel running alters patterns of uncontrollable stress-induced cfos mRNA expression in rat dorsal striatum direct and indirect pathways: A possible role for plasticity in adenosine receptors. Behav Brain Res. 2014 Oct 01; 272:252-63.Behav Brain Res2014-07-11T00:00:002014Wheel running alters patterns of uncontrollable stress-induced cfos mRNA expression in rat dorsal striatum direct and indirect pathways: A possible role for plasticity in adenosine receptors.Authorship 670661Authorship 682237Authorship 685324Authorship 691093Authorship 697735Authorship 710551Authorship 721624Authorship 1164091025259839Beninson LA, Brown PN, Loughridge AB, Saludes JP, Maslanik T, Hills AK, Woodworth T, Craig W, Yin H, Fleshner MPloS oneBeninson LA, Brown PN, Loughridge AB, Saludes JP, Maslanik T, Hills AK, Woodworth T, Craig W, Yin H, Fleshner M. Acute stressor exposure modifies plasma exosome-associated heat shock protein 72 (Hsp72) and microRNA (miR-142-5p and miR-203). PLoS One. 2014; 9(9):e108748.PLoS One2014-09-26T00:00:002014Acute stressor exposure modifies plasma exosome-associated heat shock protein 72 (Hsp72) and microRNA (miR-142-5p and miR-203).Authorship 735503Authorship 745215Authorship 755012Authorship 755305Authorship 7554712Authorship 760241Authorship 1175024Authorship 117515325368585Greenwood BN, Thompson RS, Opp MR, Fleshner MFrontiers in psychiatryGreenwood BN, Thompson RS, Opp MR, Fleshner M. Repeated exposure to conditioned fear stress increases anxiety and delays sleep recovery following exposure to an acute traumatic stressor. Front Psychiatry. 2014; 5:146.Front Psychiatry2014-10-20T00:00:002014Repeated exposure to conditioned fear stress increases anxiety and delays sleep recovery following exposure to an acute traumatic stressor.25379216Thompson RS, Strong PV, Fleshner MBehavioral sciences (Basel, Switzerland)Thompson RS, Strong PV, Fleshner M. Physiological consequences of repeated exposures to conditioned fear. Behav Sci (Basel). 2012 Jun; 2(2):57-78.Behav Sci (Basel)2012-05-18T00:00:002012Physiological consequences of repeated exposures to conditioned fear.Authorship 775135Authorship 776633Authorship 1175671Authorship 117713225392482van Praag H, Fleshner M, Schwartz MW, Mattson MPThe Journal of neuroscience : the official journal of the Society for Neurosciencevan Praag H, Fleshner M, Schwartz MW, Mattson MP. Exercise, energy intake, glucose homeostasis, and the brain. J Neurosci. 2014 Nov 12; 34(46):15139-49.J Neurosci2014-11-12T00:00:002014Exercise, energy intake, glucose homeostasis, and the brain.24481547Fleshner M, Greenwood BN, Yirmiya RCurrent topics in behavioral neurosciencesFleshner M, Greenwood BN, Yirmiya R. Neuronal-glial mechanisms of exercise-evoked stress robustness. Curr Top Behav Neurosci. 2014; 18:1-12.Curr Top Behav Neurosci2014-01-01T00:00:002014Neuronal-glial mechanisms of exercise-evoked stress robustness.Authorship 784006Authorship 784596Authorship 79326Authorship 79796Authorship 798501