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Michael Bristow

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-5453

    Collapse Research 
    Collapse research activities and funding
    R01HL071118     (BRISTOW, MICHAEL R.)Jul 1, 2002 - Jun 30, 2004
    NIH
    Dynamic Expression Profiling in the Intact Human Heart
    Role: Principal Investigator
    R01HL061640     (BRISTOW, MICHAEL R.)Sep 21, 1998 - Aug 31, 2004
    NIH
    CONTRACTILE PROTEIN EXPRESSION IN FAILING HUMAN HEART
    Role: Principal Investigator
    T32HL007822     (BUTTRICK, PETER N.)Jul 1, 1996 - Jun 30, 2024
    NIH
    Post Graduate Studies in Cardiovascular Research
    Role: Co-Principal Investigator
    R01HL048013     (BRISTOW, MICHAEL R.)May 1, 1993 - Feb 28, 2009
    NIH
    Genetic-Adrenergic Interactions in Myocardial Failure
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mallabone M, Labib D, Abdelhaleem A, Dykstra S, Thompson RB, Paterson DI, Thompson SK, Hasanzadeh F, Mikami Y, Rivest S, Flewitt J, Feng Y, Macdonald M, King M, Bristow M, Kolman L, Howarth AG, Lydell CP, Miller RJH, Fine NM, White JA. Sex-based differences in the phenotypic expression and prognosis of idiopathic non-ischaemic cardiomyopathy: a cardiovascular magnetic resonance study. Eur Heart J Cardiovasc Imaging. 2024 May 31; 25(6):804-813. PMID: 38236156.
      View in: PubMed
    2. Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA. Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants. J Am Heart Assoc. 2023 12 19; 12(24):e029938. PMID: 38108245.
      View in: PubMed
    3. Dimond MG, Ibrahim NE, Fiuzat M, McMurray JJV, Lindenfeld J, Ahmad T, Bozkurt B, Bristow MR, Butler J, Carson PE, Felker GM, Jessup M, Murillo J, Kondo T, Solomon SD, Abraham WT, O'Connor CM, Psotka MA. Left Ventricular Ejection Fraction and the Future of Heart?Failure Phenotyping. JACC Heart Fail. 2024 Mar; 12(3):451-460. PMID: 38099892.
      View in: PubMed
    4. Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate ?2-adrenoceptors. Nat Commun. 2023 Nov 30; 14(1):7866. PMID: 38036531.
      View in: PubMed
    5. Dimond MG, Fiuzat M, Mentz RJ, Lala-Trindade A, Whellan DJ, Walsh MN, Costanzo MR, Yehya A, Desvigne-Nickens P, Malik F, O'Connor CM, Bristow MR. Rewarding Site-Based Research: A Step Toward Improving the Ecosystem of?Heart?Failure Clinical Trials. JACC Heart Fail. 2024 01; 12(1):226-228. PMID: 37804314.
      View in: PubMed
    6. Martin TG, Juarros MA, Cleveland JC, Bristow MR, Ambardekar AV, Buttrick PM, Leinwand LA. Assessment of Autophagy Markers Suggests Increased Activity Following LVAD Therapy. JACC Basic Transl Sci. 2023 Sep; 8(9):1043-1056. PMID: 37791310.
      View in: PubMed
    7. Tatman PD, Kao DP, Chatfield KC, Carroll IA, Wagner JA, Jonas ER, Sucharov CC, Port JD, Lowes BD, Minobe WA, Huebler SP, Karimpour-Fard A, Rodriguez EM, Liggett SB, Bristow MR. An extensive ?1-adrenergic receptor gene signaling network regulates molecular remodeling in dilated cardiomyopathies. JCI Insight. 2023 08 22; 8(16). PMID: 37606047.
      View in: PubMed
    8. Hess CN, Hsia J, Carroll IA, Nehler MR, Ruf W, Morrow DA, Nicolau JC, Berwanger O, Szarek M, Capell WH, Johri S, Pursley MS, Gupta R, Meehan PS, Franchi F, Effron MB, Marshall D, Graybill CA, Huebler SP, Keuer T, Bristow MR, Bonaca MP. Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial. Arterioscler Thromb Vasc Biol. 2023 08; 43(8):1572-1582. PMID: 37381988.
      View in: PubMed
    9. Koupenova M, Chung MK, Bristow MR. COVID-19 and the Cardiovascular System: Requiem for a Medical Minotaur. Circ Res. 2023 05 12; 132(10):1255-1258. PMID: 37167357.
      View in: PubMed
    10. Altman NL, Berning AA, Mann SC, Quaife RA, Gill EA, Auerbach SR, Campbell TB, Bristow MR. Vaccination-Associated Myocarditis and Myocardial Injury. Circ Res. 2023 05 12; 132(10):1338-1357. PMID: 37167355.
      View in: PubMed
    11. Chevalier P, Roy P, Bessi?re F, Morel E, Ankou B, Morgan G, Halder I, London B, Minobe WA, Slavov D, Delini?re A, Bochaton T, Paganelli F, Lesavre N, Boiteux C, Mansourati J, Maury P, Clerici G, Winum PF, Huebler SP, Carroll IA, Bristow MR. Impact of Neuroeffector Adrenergic Receptor Polymorphisms on Incident Ventricular Fibrillation During Acute Myocardial Ischemia. J Am Heart Assoc. 2023 03 21; 12(6):e025368. PMID: 36926933.
      View in: PubMed
    12. Annex BH, Bristow MR, Frangogiannis NG, Kelly DP, Kontaridis M, Libby P, MacLellan WR, McNamara CA, Mann DL, Pitt GS, Sipido KR. JACC: Basic to Translational Science Top?Reviewers 2022: With?Appreciation?and?Gratitude. JACC Basic Transl Sci. 2023 Feb; 8(2):236. PMID: 36908670.
      View in: PubMed
    13. Rubino M, Travers JG, Headrick AL, Enyart BT, Lemieux ME, Cavasin MA, Schwisow JA, Hardy EJ, Kaltenbacher KJ, Felisbino MB, Jonas E, Ambardekar AV, Bristow MR, Koch KA, McKinsey TA. Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart. Circ Res. 2023 01 06; 132(1):10-29. PMID: 36475698.
      View in: PubMed
    14. Altman NL, Berning AA, Saxon CE, Adamek KE, Wagner JA, Slavov D, Quaife RA, Gill EA, Minobe WA, Jonas ER, Carroll IA, Huebler SP, Raines J, Messenger JC, Ambardekar AV, Mestroni L, Rosenberg RM, Rove J, Campbell TB, Bristow MR. Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination. JACC Basic Transl Sci. 2023 Feb; 8(2):124-137. PMID: 36281440.
      View in: PubMed
    15. Felker GM, Buttrick P, Rosenzweig A, Abel ED, Allen LA, Bristow M, Das S, DeVore AD, Drakos SG, Fang JC, Freedman JE, Hernandez AF, Li DY, McKinsey TA, Newton-Cheh C, Rogers JG, Shah RV, Shah SH, Stehlik J, Selzman CH. Heart Failure Strategically Focused Research Network: Summary of Results and Future Directions. J Am Heart Assoc. 2022 09 20; 11(18):e025517. PMID: 36073647.
      View in: PubMed
    16. Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714. PMID: 35862102.
      View in: PubMed
    17. Cleland JGF, Bristow MR, Freemantle N, Olshansky B, Gras D, Saxon L, Tavazzi L, Boehmer J, Ghio S, Feldman AM, Daubert JC, de Mets D. The effect of cardiac resynchronization without a defibrillator on morbidity and mortality: an individual patient data meta-analysis of COMPANION and CARE-HF. Eur J Heart Fail. 2022 06; 24(6):1080-1090. PMID: 35490339.
      View in: PubMed
    18. Annex BH, Bristow MR, Frangogiannis NG, Kelly DP, Kontaridis MI, Libby P, Robb MacLellan W, McNamara CA, Mann DL, Pitt GS, Sipido KR. JACC: Basic to Translational Science Top Reviewers 2021: With Appreciation. JACC Basic Transl Sci. 2022 Feb; 7(2):192. PMID: 35257046.
      View in: PubMed
    19. Bristow MR, Mann DL. Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction: A Role for ?-Blockade? JACC Basic Transl Sci. 2022 Feb; 7(2):128-130. PMID: 35257039.
      View in: PubMed
    20. Chen SN, Lam CK, Wan YW, Gao S, Malak OA, Zhao SR, Lombardi R, Ambardekar AV, Bristow MR, Cleveland J, Gigli M, Sinagra G, Graw S, Taylor MRG, Wu JC, Mestroni L. Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy. Sci Adv. 2022 Feb 25; 8(8):eabk0052. PMID: 35196083.
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    21. Thornton CS, Huntley K, Berenger BM, Bristow M, Evans DH, Fonseca K, Franko A, Gillrie MR, Lin YC, Povitz M, Shafey M, Conly JM, Tremblay A. Prolonged SARS-CoV-2 infection following rituximab treatment: clinical course and response to therapeutic interventions correlated with quantitative viral cultures and cycle threshold values. Antimicrob Resist Infect Control. 2022 02 05; 11(1):28. PMID: 35123573.
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    22. Li H, Trager LE, Liu X, Hastings MH, Xiao C, Guerra J, To S, Li G, Yeri A, Rodosthenous R, Silverman MG, Das S, Ambardekar AV, Bristow MR, Gonz?lez-Rosa JM, Rosenzweig A. lncExACT1 and DCHS2 Regulate Physiological and Pathological Cardiac Growth. Circulation. 2022 04 19; 145(16):1218-1233. PMID: 35114812.
      View in: PubMed
    23. Purmah Y, Cornhill A, Lei LY, Dykstra S, Mikami Y, Satriano A, Labib D, Flewitt J, Rivest S, Sandonato R, Seib M, Howarth AG, Lydell CP, Heydari B, Merchant N, Bristow M, Kolman L, Fine NM, White JA. Mid-wall striae fibrosis predicts heart failure admission, composite heart failure events, and life-threatening arrhythmias in dilated cardiomyopathy. Sci Rep. 2022 02 02; 12(1):1739. PMID: 35110630.
      View in: PubMed
    24. Hess CN, Capell WH, Bristow MR, Ruf W, Szarek M, Morrow DA, Nicolau JC, Graybill CA, Marshall D, Hsia J, Bonaca MP. Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial. Am Heart J. 2022 04; 246:136-143. PMID: 34986394.
      View in: PubMed
    25. Abraham WT, Piccini JP, Dufton C, Carroll IA, Healey JS, O'Connor CM, Marshall D, Aleong R, van Veldhuisen DJ, Rienstra M, Wilton SB, White M, Sauer WH, Anand IS, Huebler SP, Connolly SJ, Bristow MR. Dose-limiting, adverse event-associated bradycardia with ?-blocker treatment of atrial fibrillation in the GENETIC-AF trial. Heart Rhythm O2. 2022 Feb; 3(1):40-49. PMID: 35243434.
      View in: PubMed
    26. Gao S, Mumme-Monheit A, Chen SN, Spector EB, Slavov D, Baralle FE, Bristow MR, Mestroni L, Taylor MRG. An LMNA synonymous variant associated with severe dilated cardiomyopathy: Case report. Am J Med Genet A. 2022 02; 188(2):600-605. PMID: 34652067.
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    27. Piccini JP, Dufton C, Carroll IA, Healey JS, Abraham WT, Khaykin Y, Aleong R, Krueger SK, Sauer WH, Wilton SB, Rienstra M, van Veldhuisen DJ, Anand IS, White M, Camm AJ, Ziegler PD, Marshall D, Bristow MR, Connolly SJ. Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype. Circ Arrhythm Electrophysiol. 2021 08; 14(8):e009591. PMID: 34270905.
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    28. Leopold JA, Kawut SM, Aldred MA, Archer SL, Benza RL, Bristow MR, Brittain EL, Chesler N, DeMan FS, Erzurum SC, Gladwin MT, Hassoun PM, Hemnes AR, Lahm T, Lima JAC, Loscalzo J, Maron BA, Rosa LM, Newman JH, Redline S, Rich S, Rischard F, Sugeng L, Tang WHW, Tedford RJ, Tsai EJ, Ventetuolo CE, Zhou Y, Aggarwal NR, Xiao L. Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop. Circ Heart Fail. 2021 06; 14(6). PMID: 34422205.
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    29. Woulfe KC, Jeffrey DA, Pires Da Silva J, Wilson CE, Mahaffey JH, Lau E, Slavov D, Hailu F, Karimpour-Fard A, Dockstader K, Bristow MR, Stauffer BL, Miyamoto SD, Sucharov CC. Serum response factor deletion 5 regulates phospholamban phosphorylation and calcium uptake. J Mol Cell Cardiol. 2021 10; 159:28-37. PMID: 34139234.
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    30. Hailu FT, Karimpour-Fard A, Toni LS, Bristow MR, Miyamoto SD, Stauffer BL, Sucharov CC. Integrated analysis of miRNA-mRNA interaction in pediatric dilated cardiomyopathy. Pediatr Res. 2022 07; 92(1):98-108. PMID: 34012027.
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    31. Doran B, Mei C, Varosy PD, Kao DP, Saxon LA, Feldman AM, DeMets D, Bristow MR. The Addition of a Defibrillator to?Resynchronization Therapy Decreases?Mortality in Patients With Nonischemic Cardiomyopathy. JACC Heart Fail. 2021 06; 9(6):439-449. PMID: 33992570.
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    32. Das M, Bristow MR, Chung MK. The Essential Vulnerability of Human Cardiac Myocytes to SARS-CoV-2. JACC Basic Transl Sci. 2021 Apr; 6(4):346-349. PMID: 33997520.
      View in: PubMed
    33. Chung MK, Zidar DA, Bristow MR, Cameron SJ, Chan T, Harding CV, Kwon DH, Singh T, Tilton JC, Tsai EJ, Tucker NR, Barnard J, Loscalzo J. COVID-19 and Cardiovascular Disease: From Bench to Bedside. Circ Res. 2021 04 16; 128(8):1214-1236. PMID: 33856918.
      View in: PubMed
    34. Purmah Y, Lei LY, Dykstra S, Mikami Y, Cornhill A, Satriano A, Flewitt J, Rivest S, Sandonato R, Seib M, Lydell CP, Howarth AG, Heydari B, Merchant N, Bristow M, Fine N, Gaztanaga J, White JA. Right Ventricular Ejection Fraction for the Prediction of Major Adverse Cardiovascular and Heart Failure-Related Events: A Cardiac MRI Based Study of 7131 Patients With Known or Suspected Cardiovascular Disease. Circ Cardiovasc Imaging. 2021 03; 14(3):e011337. PMID: 33722059.
      View in: PubMed
    35. Beldhuis IE, Myhre PL, Bristow M, Claggett B, Damman K, Fang JC, Fleg JL, McKinlay S, Lewis EF, O'Meara E, Pitt B, Shah SJ, Vardeny O, Voors AA, Pfeffer MA, Solomon SD, Desai AS. Spironolactone in Patients With Heart?Failure, Preserved Ejection Fraction, and Worsening Renal Function. J Am Coll Cardiol. 2021 03 09; 77(9):1211-1221. PMID: 33663739.
      View in: PubMed
    36. Knight WE, Cao Y, Lin YH, Chi C, Bai B, Sparagna GC, Zhao Y, Du Y, Londono P, Reisz JA, Brown BC, Taylor MRG, Ambardekar AV, Cleveland JC, McKinsey TA, Jeong MY, Walker LA, Woulfe KC, D'Alessandro A, Chatfield KC, Xu H, Bristow MR, Buttrick PM, Song K. Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy. Stem Cell Reports. 2021 03 09; 16(3):519-533. PMID: 33636116.
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    37. Bhatt AS, Abraham WT, Lindenfeld J, Bristow M, Carson PE, Felker GM, Fonarow GC, Greene SJ, Psotka MA, Solomon SD, Stockbridge N, Teerlink JR, Vaduganathan M, Wittes J, Fiuzat M, O'Connor CM, Butler J. Treatment of HF in an Era of Multiple?Therapies: Statement From the HF Collaboratory. JACC Heart Fail. 2021 01; 9(1):1-12. PMID: 33309582.
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    38. O'Connor CM, Bristow MR. Changing U.S. Heart Failure Research Culture: Part 2-Recognizing Frontline Investigators and Coordinators. JACC Heart Fail. 2020 12; 8(12):1050-1051. PMID: 33272381.
      View in: PubMed
    39. Bristow MR, Zisman LS, Altman NL, Gilbert EM, Lowes BD, Minobe WA, Slavov D, Schwisow JA, Rodriguez EM, Carroll IA, Keuer TA, Buttrick PM, Kao DP. Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium. JACC Basic Transl Sci. 2020 Sep; 5(9):871-883. PMID: 32838074.
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    40. Haywood ME, Cocciolo A, Porter KF, Dobrinskikh E, Slavov D, Graw SL, Reece TB, Ambardekar AV, Bristow MR, Mestroni L, Taylor MRG. Transcriptome signature of ventricular arrhythmia in dilated cardiomyopathy reveals increased fibrosis and activated TP53. J Mol Cell Cardiol. 2020 02; 139:124-134. PMID: 31958463.
      View in: PubMed
    41. Toni LS, Carroll IA, Jones KL, Schwisow JA, Minobe WA, Rodriguez EM, Altman NL, Lowes BD, Gilbert EM, Buttrick PM, Kao DP, Bristow MR. Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance. PLoS One. 2019; 14(8):e0221519. PMID: 31469842.
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    42. Piccini JP, Abraham WT, Dufton C, Carroll IA, Healey JS, van Veldhuisen DJ, Sauer WH, Anand IS, White M, Wilton SB, Aleong R, Rienstra M, Krueger SK, Ayala-Paredes F, Khaykin Y, Merkely B, Miloradovic V, Wranicz JK, Ilkhanoff L, Ziegler PD, Davis G, Emery LL, Marshall D, Kao DP, Bristow MR, Connolly SJ. Bucindolol for the Maintenance of Sinus?Rhythm in a Genotype-Defined HF?Population: The GENETIC-AF Trial. JACC Heart Fail. 2019 07; 7(7):586-598. PMID: 31042551.
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    43. Sucharov CC, Nakano SJ, Slavov D, Schwisow JA, Rodriguez E, Nunley K, Medway A, Stafford N, Nelson P, McKinsey TA, Movsesian M, Minobe W, Carroll IA, Taylor MRG, Bristow MR. A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium. J Am Coll Cardiol. 2019 03 19; 73(10):1173-1184. PMID: 30871701.
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    44. Shamoun F, De Marco T, DeMets D, Mei C, Lindenfeld J, Saxon LA, Boehmer JP, Leigh J, Yong P, Feldman AM, Bristow MR. Impact of Degree of Left Ventricular Remodeling on Clinical Outcomes From Cardiac Resynchronization Therapy. JACC Heart Fail. 2019 04; 7(4):281-290. PMID: 30738980.
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    45. Sweet ME, Cocciolo A, Slavov D, Jones KL, Sweet JR, Graw SL, Reece TB, Ambardekar AV, Bristow MR, Mestroni L, Taylor MRG. Transcriptome analysis of human heart failure reveals dysregulated cell adhesion in dilated cardiomyopathy and activated immune pathways in ischemic heart failure. BMC Genomics. 2018 Nov 12; 19(1):812. PMID: 30419824.
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    46. Myers VD, Gerhard GS, McNamara DM, Tomar D, Madesh M, Kaniper S, Ramsey FV, Fisher SG, Ingersoll RG, Kasch-Semenza L, Wang J, Hanley-Yanez K, Lemster B, Schwisow JA, Ambardekar AV, Degann SH, Bristow MR, Sheppard R, Alexis JD, Tilley DG, Kontos CD, McClung JM, Taylor AL, Yancy CW, Khalili K, Seidman JG, Seidman CE, McTiernan CF, Cheung JY, Feldman AM. Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals. JAMA Cardiol. 2018 10 01; 3(10):929-938. PMID: 30140897.
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    47. Parikh KS, Fiuzat M, Davis G, Neely M, Blain-Nelson P, Whellan DJ, Abraham WT, Adams KF, Felker GM, Liggett SB, O'Connor CM, Bristow MR. Dose Response of ?-Blockers in Adrenergic Receptor Polymorphism Genotypes. Circ Genom Precis Med. 2018 08; 11(8):e002210. PMID: 30354340.
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    48. O'Connor CM, Bristow MR. Changing the Research Culture in the United States. JACC Heart Fail. 2018 Apr; 6(4):344-345. PMID: 29598937.
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    49. Bristow MR, Leinwand LA, Olson EN. Entrepreneurialism in the Translational?Biologic Sciences: Why, How, and However. JACC Basic Transl Sci. 2018 Feb; 3(1):1-8. PMID: 30062188.
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    50. Begay RL, Graw SL, Sinagra G, Asimaki A, Rowland TJ, Slavov DB, Gowan K, Jones KL, Brun F, Merlo M, Miani D, Sweet M, Devaraj K, Wartchow EP, Gigli M, Puggia I, Salcedo EE, Garrity DM, Ambardekar AV, Buttrick P, Reece TB, Bristow MR, Saffitz JE, Mestroni L, Taylor MRG. Filamin C Truncation Mutations Are Associated With Arrhythmogenic Dilated?Cardiomyopathy and Changes in?the Cell-Cell Adhesion Structures. JACC Clin Electrophysiol. 2018 04; 4(4):504-514. PMID: 30067491.
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    51. Bristow MR. Contractile reserve and the response to cardiac resynchronization therapy. Int J Cardiol. 2018 02 01; 252:234-235. PMID: 29249434.
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    52. O'Connor CM, Psotka MA, Fiuzat M, Lindenfeld J, Abraham WT, Bristow MR, Canos D, Harrington RA, Hillebrenner M, Jessup M, Malik FI, Solomon SD, Stockbridge N, Tcheng JE, Unger EF, Whellan DJ, Zuckerman B, Califf RM. Improving Heart Failure Therapeutics Development in the United States: The?Heart?Failure?Collaboratory. J Am Coll Cardiol. 2018 01 30; 71(4):443-453. PMID: 29389362.
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    53. Piccini JP, Connolly SJ, Abraham WT, Healey JS, Steinberg BA, Al-Khalidi HR, Dignacco P, van Veldhuisen DJ, Sauer WH, White M, Wilton SB, Anand IS, Dufton C, Marshall DA, Aleong RG, Davis GW, Clark RL, Emery LL, Bristow MR. A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial. Am Heart J. 2018 05; 199:51-58. PMID: 29754666.
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    54. Shah P, Bristow MR, Port JD. MicroRNAs in Heart Failure, Cardiac Transplantation, and Myocardial Recovery: Biomarkers with Therapeutic Potential. Curr Heart Fail Rep. 2017 12; 14(6):454-464. PMID: 28940102.
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    55. Bristow MR, Kao DP, Breathett KK, Altman NL, Gorcsan J, Gill EA, Lowes BD, Gilbert EM, Quaife RA, Mann DL. Structural and Functional Phenotyping of the Failing Heart: Is the Left Ventricular Ejection Fraction Obsolete? JACC Heart Fail. 2017 11; 5(11):772-781. PMID: 29096787.
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    56. Leary PJ, Kronmal RA, Bluemke DA, Buttrick PM, Jones KL, Kao DP, Kawut SM, Krieger EV, Lima JA, Minobe W, Ralph DD, Tedford RJ, Weiss NS, Bristow MR. Histamine H2 Receptor Polymorphisms, Myocardial Transcripts, and Heart Failure (from the Multi-Ethnic Study of Atherosclerosis and Beta-Blocker Effect on Remodeling and Gene Expression Trial). Am J Cardiol. 2018 01 15; 121(2):256-261. PMID: 29191567.
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    57. Bristow MR, Altman NL. Heart Rate in Preserved Ejection?Fraction?Heart Failure. JACC Heart Fail. 2017 11; 5(11):792-794. PMID: 29032133.
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    58. Kalscheur MM, Saxon LA, Lee BK, Steinberg JS, Mei C, Buhr KA, DeMets DL, Bristow MR, Singh SN. Outcomes of cardiac resynchronization therapy in patients with intermittent atrial fibrillation or atrial flutter in the COMPANION trial. Heart Rhythm. 2017 06; 14(6):858-865. PMID: 28323173.
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    59. Bristow MR. Genetic variation expressed in the brain may impact heart failure. Eur J Heart Fail. 2017 03; 19(3):324-325. PMID: 28251773.
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    60. Sucharov CC, Kao DP, Port JD, Karimpour-Fard A, Quaife RA, Minobe W, Nunley K, Lowes BD, Gilbert EM, Bristow MR. Myocardial microRNAs associated with reverse remodeling in human heart failure. JCI Insight. 2017 01 26; 2(2):e89169. PMID: 28138556.
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    61. Port JD, Bristow MR. Fine Tuning Adenylyl Cyclase as a (Gene)?Therapy for Heart Failure. JACC Basic Transl Sci. 2016 Dec; 1(7):630-632. PMID: 30167546.
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    62. Bristow MR, Sharma K, Assmann SF, Linas S, Gersh BJ, Grady C, Rice MM, Singh S, Boineau R, McKinlay SM, Greenberg BH. Data and Safety Monitoring Board evaluation and management of a renal adverse event signal in TOPCAT. Eur J Heart Fail. 2017 04; 19(4):457-465. PMID: 27873428.
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    63. Leary PJ, Bristow MR. Reply: Is Histamine H2 Receptor a Real?Promising Target for Prevention or?Treatment?of Heart Failure? J Am Coll Cardiol. 2016 11 01; 68(18):2029-2030. PMID: 27788859.
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    64. Breathett K, Allen LA, Udelson J, Davis G, Bristow M. Changes in Left Ventricular Ejection Fraction Predict Survival and Hospitalization in Heart Failure With Reduced Ejection Fraction. Circ Heart Fail. 2016 Oct; 9(10). PMID: 27656000.
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    65. Bristow MR, Saxon LA, Feldman AM, Mei C, Anderson SA, DeMets DL. Lessons Learned and Insights Gained in?the?Design, Analysis, and Outcomes of?the COMPANION Trial. JACC Heart Fail. 2016 07; 4(7):521-535. PMID: 27289408.
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    66. Leary PJ, Tedford RJ, Bluemke DA, Bristow MR, Heckbert SR, Kawut SM, Krieger EV, Lima JA, Masri CS, Ralph DD, Shea S, Weiss NS, Kronmal RA. Histamine H2 Receptor Antagonists, Left?Ventricular Morphology, and Heart?Failure?Risk: The MESA Study. J Am Coll Cardiol. 2016 Apr 05; 67(13):1544-1552. PMID: 27150686.
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    67. Bristow MR, Enciso JS, Gersh BJ, Grady C, Rice MM, Singh S, Sopko G, Boineau R, Rosenberg Y, Greenberg BH. Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations. JACC Basic Transl Sci. 2016 Apr; 1(3):180-189. PMID: 27747305.
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    150. Carniel E, Taylor MR, Sinagra G, Di Lenarda A, Ku L, Fain PR, Boucek MM, Cavanaugh J, Miocic S, Slavov D, Graw SL, Feiger J, Zhu XZ, Dao D, Ferguson DA, Bristow MR, Mestroni L. Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy. Circulation. 2005 Jul 05; 112(1):54-9. PMID: 15998695.
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    152. Kinugawa K, Jeong MY, Bristow MR, Long CS. Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinase. Mol Endocrinol. 2005 Jun; 19(6):1618-28. PMID: 15831522.
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    153. Domanski M, Fleg J, Bristow M, Knox S. The effect of gender on outcome in digitalis-treated heart failure patients. J Card Fail. 2005 Mar; 11(2):83-6. PMID: 15732025.
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    154. Movsesian MA, Bristow MR. Alterations in cAMP-mediated signaling and their role in the pathophysiology of dilated cardiomyopathy. Curr Top Dev Biol. 2005; 68:25-48. PMID: 16124995.
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    156. Pittenger B, Gill EA, Holcslaw TL, Bristow MR. Relation of dose of carvedilol to reduction in QT dispersion in patients with mild to moderate heart failure secondary to ischemic or to idiopathic dilated cardiomyopathy. Am J Cardiol. 2004 Dec 01; 94(11):1459-62. PMID: 15566928.
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    157. Taylor MR, Bristow MR. The emerging pharmacogenomics of the beta-adrenergic receptors. Congest Heart Fail. 2004 Nov-Dec; 10(6):281-8. PMID: 15591842.
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    158. Sucharov CC, Helmke SM, Langer SJ, Perryman MB, Bristow M, Leinwand L. The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression. Mol Cell Biol. 2004 Oct; 24(19):8705-15. PMID: 15367688.
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    159. Bristow MR, Krause-Steinrauf H, Nuzzo R, Liang CS, Lindenfeld J, Lowes BD, Hattler B, Abraham WT, Olson L, Krueger S, Thaneemit-Chen S, Hare JM, Loeb HS, Domanski MJ, Eichhorn EJ, Zelis R, Lavori P. Effect of baseline or changes in adrenergic activity on clinical outcomes in the beta-blocker evaluation of survival trial. Circulation. 2004 Sep 14; 110(11):1437-42. PMID: 15337700.
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    160. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, Carson P, DiCarlo L, DeMets D, White BG, DeVries DW, Feldman AM. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004 May 20; 350(21):2140-50. PMID: 15152059.
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    161. Helmke SM, Yen CY, Cios KJ, Nunley K, Bristow MR, Duncan MW, Perryman MB. Simultaneous quantification of human cardiac alpha- and beta-myosin heavy chain proteins by MALDI-TOF mass spectrometry. Anal Chem. 2004 Mar 15; 76(6):1683-9. PMID: 15018568.
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    162. Shakar SF, Lowes BD, Lindenfeld J, Zolty R, Simon M, Robertson AD, Bristow MR, Wolfel EE. Peak oxygen consumption and outcome in heart failure patients chronically treated with beta-blockers. J Card Fail. 2004 Feb; 10(1):15-20. PMID: 14966770.
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    164. Zisman LS, Meixell GE, Bristow MR, Canver CC. Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate. Circulation. 2003 Oct 07; 108(14):1679-81. PMID: 14504185.
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    165. Zisman LS, Keller RS, Weaver B, Lin Q, Speth R, Bristow MR, Canver CC. Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2. Circulation. 2003 Oct 07; 108(14):1707-12. PMID: 14504186.
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    167. Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L. Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter. J Biol Chem. 2003 Aug 15; 278(33):31233-9. PMID: 12754214.
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    168. Bristow MR. Microarray measurements of gene expression before and after left ventricular assist device placement. J Am Coll Cardiol. 2003 Apr 02; 41(7):1107-8. PMID: 12679208.
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    169. Linseman JV, Bristow MR. Drug therapy and heart failure prevention. Circulation. 2003 Mar 11; 107(9):1234-6. PMID: 12628939.
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    171. Bristow M. Antiadrenergic therapy of chronic heart failure: surprises and new opportunities. Circulation. 2003 Mar 04; 107(8):1100-2. PMID: 12615784.
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    173. Rathore SS, Curtis JP, Wang Y, Bristow MR, Krumholz HM. Association of serum digoxin concentration and outcomes in patients with heart failure. JAMA. 2003 Feb 19; 289(7):871-8. PMID: 12588271.
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    176. Abraham WT, Gilbert EM, Lowes BD, Minobe WA, Larrabee P, Roden RL, Dutcher D, Sederberg J, Lindenfeld JA, Wolfel EE, Shakar SF, Ferguson D, Volkman K, Linseman JV, Quaife RA, Robertson AD, Bristow MR. Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype. Mol Med. 2002 Nov; 8(11):750-60. PMID: 12520092.
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    182. Lindenfeld J, Robertson AD, Lowes BD, Bristow MR. Aspirin impairs reverse myocardial remodeling in patients with heart failure treated with beta-blockers. J Am Coll Cardiol. 2001 Dec; 38(7):1950-6. PMID: 11738299.
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    187. Loh E, Elkayam U, Cody R, Bristow M, Jaski B, Colucci WS. A randomized multicenter study comparing the efficacy and safety of intravenous milrinone and intravenous nitroglycerin in patients with advanced heart failure. J Card Fail. 2001 Jun; 7(2):114-21. PMID: 11420762.
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    191. Shakar SF, Bristow MR. Low-level inotropic stimulation with type III phosphodiesterase inhibitors in patients with advanced symptomatic chronic heart failure receiving beta-blocking agents. Curr Cardiol Rep. 2001 May; 3(3):224-31. PMID: 11305977.
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    192. Sinagra G, Di Lenarda A, Brodsky GL, Taylor MR, Muntoni F, Pinamonti B, Carniel E, Driussi M, Bristow MR, Mestroni L. Current perspective new insights into the molecular basis of familial dilated cardiomyopathy. Ital Heart J. 2001 Apr; 2(4):280-6. PMID: 11374497.
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    196. Bristow M. Of phospholamban, mice, and humans with heart failure. Circulation. 2001 Feb 13; 103(6):787-8. PMID: 11171783.
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    198. Braunwald E, Bristow MR. Congestive heart failure: fifty years of progress. Circulation. 2000 Nov 14; 102(20 Suppl 4):IV14-23. PMID: 11080127.
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    199. Bristow M. Etomoxir: a new approach to treatment of chronic heart failure. Lancet. 2000 Nov 11; 356(9242):1621-2. PMID: 11089814.
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    202. Bristow MR. What type of beta-blocker should be used to treat chronic heart failure? Circulation. 2000 Aug 01; 102(5):484-6. PMID: 10920055.
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    212. Quaife RA, Lynch D, Badesch DB, Voelkel NF, Lowes BD, Robertson AD, Bristow MR. Right ventricular phenotypic characteristics in subjects with primary pulmonary hypertension or idiopathic dilated cardiomyopathy. J Card Fail. 1999 Mar; 5(1):46-54. PMID: 10194660.
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    243. Ma H, Hammond EH, Taylor DO, Yowell RL, Bristow MR, O'Connell JB, Renlund DG. The repetitive histologic pattern of vascular cardiac allograft rejection. Increased incidence associated with longer exposure to prophylactic murine monoclonal anti-CD3 antibody (OKT3). Transplantation. 1996 Jul 27; 62(2):205-10. PMID: 8755817.
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    244. Packer M, Bristow MR, Cohn JN, Colucci WS, Fowler MB, Gilbert EM, Shusterman NH. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. N Engl J Med. 1996 May 23; 334(21):1349-55. PMID: 8614419.
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    245. Pende A, Tremmel KD, DeMaria CT, Blaxall BC, Minobe WA, Sherman JA, Bisognano JD, Bristow MR, Brewer G, Port J. Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway. J Biol Chem. 1996 Apr 05; 271(14):8493-501. PMID: 8626551.
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    247. Richardson P, McKenna W, Bristow M, Maisch B, Mautner B, O'Connell J, Olsen E, Thiene G, Goodwin J, Gyarfas I, Martin I, Nordet P. Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies. Circulation. 1996 Mar 01; 93(5):841-2. PMID: 8598070.
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    248. Focaccio A, Peeters G, Movsesian M, Roden R, Eki Y, Krall J, Bristow MR. Mechanism of action of OPC-8490 in human ventricular myocardium. Circulation. 1996 Feb 15; 93(4):817-25. PMID: 8641012.
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    249. Renlund DG, Taylor DO, Ensley RD, O'Connell JB, Gilbert EM, Bristow MR, Ma H, Yanowitz FG. Exercise capacity after heart transplantation: influence of donor and recipient characteristics. J Heart Lung Transplant. 1996 Jan; 15(1 Pt 1):16-24. PMID: 8820079.
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    250. White M, Yanowitz F, Gilbert EM, Larrabee P, O'Connell JB, Anderson JL, Renlund D, Mealey P, Abraham WT, Bristow MR. Role of beta-adrenergic receptor downregulation in the peak exercise response in patients with heart failure due to idiopathic dilated cardiomyopathy. Am J Cardiol. 1995 Dec 15; 76(17):1271-6. PMID: 7503009.
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    251. Costanzo MR, Augustine S, Bourge R, Bristow M, O'Connell JB, Driscoll D, Rose E. Selection and treatment of candidates for heart transplantation. A statement for health professionals from the Committee on Heart Failure and Cardiac Transplantation of the Council on Clinical Cardiology, American Heart Association. Circulation. 1995 Dec 15; 92(12):3593-612. PMID: 8521589.
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    252. Gilbert EM, Hershberger RE, Wiechmann RJ, Movsesian MA, Bristow MR. Pharmacologic and hemodynamic effects of combined beta-agonist stimulation and phosphodiesterase inhibition in the failing human heart. Chest. 1995 Dec; 108(6):1524-32. PMID: 7497755.
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    253. Jaggers J, Fullerton DA, Campbell DN, Andrea B, Jones SD, Brown JM, Wolfel EE, Lindenfeld J, Grover FL, Bristow MR. Cardiac allograft failure: successful use of biventricular assist device. Ann Thorac Surg. 1995 Nov; 60(5):1409-11. PMID: 8526640.
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    254. Bristow MR, Abraham WT. Anti-adrenergic effects of angiotensin converting enzyme inhibitors. Eur Heart J. 1995 Nov; 16 Suppl K:37-41. PMID: 8869134.
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    255. Bristow MR, Gilbert EM. Improvement in cardiac myocyte function by biological effects of medical therapy: a new concept in the treatment of heart failure. Eur Heart J. 1995 Jul; 16 Suppl F:20-31. PMID: 8521881.
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    256. Olsen SL, Gilbert EM, Renlund DG, Taylor DO, Yanowitz FD, Bristow MR. Carvedilol improves left ventricular function and symptoms in chronic heart failure: a double-blind randomized study. J Am Coll Cardiol. 1995 May; 25(6):1225-31. PMID: 7722114.
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    257. Deisher TA, Ginsburg R, Fowler MB, Billingham ME, Bristow MR. Spontaneous reversibility of catecholamine-induced cardiotoxicity in rats. Am J Cardiovasc Pathol. 1995; 5(1):79-88. PMID: 8838159.
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    258. Abraham WT, Raynolds MV, Gottschall B, Badesch DB, Wynne KM, Groves BM, Lowes BD, Bristow MR, Perryman MB, Voelkel NF. Importance of angiotensin-converting enzyme in pulmonary hypertension. Cardiology. 1995; 86 Suppl 1:9-15. PMID: 7614507.
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    259. Hunt SA, Bristow MR, Kubo SH, O'Connell JB, Young JB. Guidelines for training in adult cardiovascular medicine. Core Cardiology Training Symposium (COCATS). Task Force 8: training in heart failure and transplantation. J Am Coll Cardiol. 1995 Jan; 25(1):29-31. PMID: 7798519.
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    260. Shaddy RE, Olsen SL, Bristow MR, Taylor DO, Bullock EA, Tani LY, Renlund DG. Efficacy and safety of metoprolol in the treatment of doxorubicin-induced cardiomyopathy in pediatric patients. Am Heart J. 1995 Jan; 129(1):197-9. PMID: 7817916.
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    261. Abraham WT, Lowes BD, White M, Ferguson DA, Scheffel CA, Wolfel EE, Lindenfeld J, Bristow MR. Comparative hemodynamic effects of OPC-18790 and dobutamine in patients with advanced heart failure. J Card Fail. 1994 Oct; 1(1):57-62. PMID: 9420633.
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    262. Taylor DO, Bristow MR, O'Connell JB, Ensley RD, Olsen SL, Hammond EH, Wagoner LE, Renlund DG. A prospective, randomized comparison of cyclophosphamide and azathioprine for early rejection prophylaxis after cardiac transplantation. Decreased sensitization to OKT3. Transplantation. 1994 Sep 27; 58(6):645-9. PMID: 7940682.
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    263. O'Connell JB, Bristow MR. Economic impact of heart failure in the United States: time for a different approach. J Heart Lung Transplant. 1994 Jul-Aug; 13(4):S107-12. PMID: 7947865.
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    264. Bristow MR, O'Connell JB, Gilbert EM, French WJ, Leatherman G, Kantrowitz NE, Orie J, Smucker ML, Marshall G, Kelly P, et al. Dose-response of chronic beta-blocker treatment in heart failure from either idiopathic dilated or ischemic cardiomyopathy. Bucindolol Investigators. Circulation. 1994 Apr; 89(4):1632-42. PMID: 7908610.
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    265. Bristow MR, Lowes BD. Low-dose inotropic therapy for ambulatory heart failure. Coron Artery Dis. 1994 Feb; 5(2):112-8. PMID: 7910094.
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    266. Bristow MR. Use of oral enoximone in pharmacologic bridging to cardiac transplantation. Z Kardiol. 1994; 83 Suppl 2:15-9. PMID: 7522381.
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    267. Waagstein F, Bristow MR, Swedberg K, Camerini F, Fowler MB, Silver MA, Gilbert EM, Johnson MR, Goss FG, Hjalmarson A. Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group. Lancet. 1993 Dec 11; 342(8885):1441-6. PMID: 7902479.
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    268. Wagoner LE, Olsen SL, Bristow MR, O'Connell JB, Taylor DO, Lappe DL, Renlund DG. Cyclophosphamide as an alternative to azathioprine in cardiac transplant recipients with suspected azathioprine-induced hepatotoxicity. Transplantation. 1993 Dec; 56(6):1415-8. PMID: 8279012.
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    269. Bristow MR, Minobe WA, Raynolds MV, Port JD, Rasmussen R, Ray PE, Feldman AM. Reduced beta 1 receptor messenger RNA abundance in the failing human heart. J Clin Invest. 1993 Dec; 92(6):2737-45. PMID: 8254027.
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    270. Raynolds MV, Bristow MR, Bush EW, Abraham WT, Lowes BD, Zisman LS, Taft CS, Perryman MB. Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy. Lancet. 1993 Oct 30; 342(8879):1073-5. PMID: 8105309.
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    271. Bristow MR. Changes in myocardial and vascular receptors in heart failure. J Am Coll Cardiol. 1993 Oct; 22(4 Suppl A):61A-71A. PMID: 8397233.
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    272. Gilbert EM, Sandoval A, Larrabee P, Renlund DG, O'Connell JB, Bristow MR. Lisinopril lowers cardiac adrenergic drive and increases beta-receptor density in the failing human heart. Circulation. 1993 Aug; 88(2):472-80. PMID: 8393389.
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    273. Olsen SL, Renlund DG, O'Connell JB, Taylor DO, Lassetter JE, Eastburn TE, Hammond EH, Bristow MR. Prevention of Pneumocystis carinii pneumonia in cardiac transplant recipients by trimethoprim sulfamethoxazole. Transplantation. 1993 Aug; 56(2):359-62. PMID: 8356591.
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    274. Feldman AM, Bristow MR, Parmley WW, Carson PE, Pepine CJ, Gilbert EM, Strobeck JE, Hendrix GH, Powers ER, Bain RP, et al. Effects of vesnarinone on morbidity and mortality in patients with heart failure. Vesnarinone Study Group. N Engl J Med. 1993 Jul 15; 329(3):149-55. PMID: 8515787.
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    275. Baldwin JC, Anderson JL, Boucek MM, Bristow MR, Jennings B, Ritsch ME, Silverman NA. 24th Bethesda conference: Cardiac transplantation. Task Force 2: Donor guidelines. J Am Coll Cardiol. 1993 Jul; 22(1):15-20. PMID: 8509535.
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    276. Deisher TA, Narita H, Zera P, Ginsburg R, Bristow MR, Billingham ME, Fowler MB, Hoffman BB. Protective effect of clentiazem against epinephrine-induced cardiac injury in rats. J Pharmacol Exp Ther. 1993 Jul; 266(1):262-9. PMID: 8392553.
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    277. Ensley RD, Bristow MR, Olsen SL, Taylor DO, Hammond EH, O'Connell JB, Dunn D, Osburn L, Jones KW, Kauffman RS, et al. The use of mycophenolate mofetil (RS-61443) in human heart transplant recipients. Transplantation. 1993 Jul; 56(1):75-82. PMID: 8333071.
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    278. Gilbert EM, Olsen SL, Renlund DG, Bristow MR. beta-adrenergic receptor regulation and left ventricular function in idiopathic dilated cardiomyopathy. Am J Cardiol. 1993 Mar 25; 71(9):23C-29C. PMID: 8096672.
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    279. Bristow MR. Pathophysiologic and pharmacologic rationales for clinical management of chronic heart failure with beta-blocking agents. Am J Cardiol. 1993 Mar 25; 71(9):12C-22C. PMID: 8096671.
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    280. Olsen SL, Wagoner LE, Hammond EH, Taylor DO, Yowell RL, Ensley RD, Bristow MR, O'Connell JB, Renlund DG. Vascular rejection in heart transplantation: clinical correlation, treatment options, and future considerations. J Heart Lung Transplant. 1993 Mar-Apr; 12(2):S135-42. PMID: 8476883.
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    281. Ratkovec RM, Hammond EH, O'Connell JB, Bristow MR, DeWitt CW, Richenbacher WE, Millar RC, Renlund DG. Outcome of cardiac transplant recipients with a positive donor-specific crossmatch--preliminary results with plasmapheresis. Transplantation. 1992 Oct; 54(4):651-5. PMID: 1412756.
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    282. Port JD, Debellis CC, Klein J, Peeters GA, Barry WH, Bristow MR. Pharmacological characterization of chick and frog beta adrenergic receptors in primary cultures of myocardial cells. J Pharmacol Exp Ther. 1992 Jul; 262(1):217-24. PMID: 1352549.
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    283. Hammond EH, Yowell RL, Price GD, Menlove RL, Olsen SL, O'Connell JB, Bristow MR, Doty DB, Millar RC, Karwande SV, et al. Vascular rejection and its relationship to allograft coronary artery disease. J Heart Lung Transplant. 1992 May-Jun; 11(3 Pt 2):S111-9. PMID: 1622989.
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    284. Merigan TC, Renlund DG, Keay S, Bristow MR, Starnes V, O'Connell JB, Resta S, Dunn D, Gamberg P, Ratkovec RM, et al. A controlled trial of ganciclovir to prevent cytomegalovirus disease after heart transplantation. N Engl J Med. 1992 Apr 30; 326(18):1182-6. PMID: 1313549.
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    285. Price GD, Olsen SL, Taylor DO, O'Connell JB, Bristow MR, Renlund DG. Corticosteroid-free maintenance immunosuppression after heart transplantation: feasibility and beneficial effects. J Heart Lung Transplant. 1992 Mar-Apr; 11(2 Pt 2):403-14. PMID: 1571338.
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    286. Bristow MR, Minobe W, Rasmussen R, Larrabee P, Skerl L, Klein JW, Anderson FL, Murray J, Mestroni L, Karwande SV, et al. Beta-adrenergic neuroeffector abnormalities in the failing human heart are produced by local rather than systemic mechanisms. J Clin Invest. 1992 Mar; 89(3):803-15. PMID: 1311717.
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    287. Anderson FL, Port JD, Reid BB, Hanson G, Kralios AC, Hershberger RE, Bristow MR. Effect of therapeutic dopamine administration on myocardial catecholamine and neuropeptide Y concentrations in the failing ventricles of patients with idiopathic dilated cardiomyopathy. J Cardiovasc Pharmacol. 1992; 20(5):800-6. PMID: 1280744.
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    288. Bristow MR, Feldman AM. Changes in the receptor-G protein-adenylyl cyclase system in heart failure from various types of heart muscle disease. Basic Res Cardiol. 1992; 87 Suppl 1:15-35. PMID: 1323259.
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    289. Marks JD, Karwande SV, Richenbacher WE, Jones KW, Doty DB, Millar RC, O'Connell JB, Renlund DG, Bristow MR, Pantalos GM, et al. Perioperative mechanical circulatory support for transplantation. J Heart Lung Transplant. 1992 Jan-Feb; 11(1 Pt 1):117-28. PMID: 1531769.
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    290. Bristow MR, Larrabee P, M?ller-Beckmann B, Minobe W, Roden R, Skerl L, Klein J, Handwerger D, Port JD. Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes. Clin Investig. 1992; 70 Suppl 1:S105-13. PMID: 1350478.
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    291. Bristow MR, Larrabee P, Minobe W, Roden R, Skerl L, Klein J, Handwerger D, Port JD, M?ller-Beckmann B. Receptor pharmacology of carvedilol in the human heart. J Cardiovasc Pharmacol. 1992; 19 Suppl 1:S68-80. PMID: 1378154.
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    292. Anderson FL, Port JD, Reid BB, Larrabee P, Hanson G, Bristow MR. Myocardial catecholamine and neuropeptide Y depletion in failing ventricles of patients with idiopathic dilated cardiomyopathy. Correlation with beta-adrenergic receptor downregulation. Circulation. 1992 Jan; 85(1):46-53. PMID: 1309447.
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    293. Feldman AM, Ray PE, Bristow MR. Expression of alpha-subunits of G proteins in failing human heart: a reappraisal utilizing quantitative polymerase chain reaction. J Mol Cell Cardiol. 1991 Dec; 23(12):1355-8. PMID: 1811054.
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    294. Richenbacher WE, Karwande SV, Shaddy RE, Renlund DG, Bristow MR, O'Connell JB, Gay WA. Cardiac transplantation in a patient with a single ventricle and transposition of the great vessels. Ann Thorac Surg. 1991 Oct; 52(4):871-3. PMID: 1929647.
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    295. Bristow MR, Anderson FL, Port JD, Skerl L, Hershberger RE, Larrabee P, O'Connell JB, Renlund DG, Volkman K, Murray J, et al. Differences in beta-adrenergic neuroeffector mechanisms in ischemic versus idiopathic dilated cardiomyopathy. Circulation. 1991 Sep; 84(3):1024-39. PMID: 1653120.
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    296. Movsesian MA, Smith CJ, Krall J, Bristow MR, Manganiello VC. Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts. J Clin Invest. 1991 Jul; 88(1):15-9. PMID: 1647414.
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    297. Feldman AM, Ray PE, Silan CM, Mercer JA, Minobe W, Bristow MR. Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction. Circulation. 1991 Jun; 83(6):1866-72. PMID: 2040039.
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    298. O'Connell JB, Gilbert EM, Renlund DG, Bristow MR. Enoximone as a bridge to heart transplantation: the Utah experience. J Heart Lung Transplant. 1991 May-Jun; 10(3):477-81. PMID: 1830222.
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    299. Hammond EH, Ensley RD, Yowell RL, Craven CM, Bristow MR, Renlund DG, O'Connell JB. Vascular rejection of human cardiac allografts and the role of humoral immunity in chronic allograft rejection. Transplant Proc. 1991 Apr; 23(2 Suppl 2):26-30. PMID: 2063418.
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    300. Feldman AM, Jackson DG, Bristow MR, Cates AE, Van Dop C. Immunodetectable levels of the inhibitory guanine nucleotide-binding regulatory proteins in failing human heart: discordance with measurements of adenylate cyclase activity and levels of pertussis toxin substrate. J Mol Cell Cardiol. 1991 Apr; 23(4):439-52. PMID: 1942080.
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    301. Hershberger RE, Feldman AM, Anderson FL, Kimball JA, Wynn JR, Bristow MR. Mr 40,000 and Mr 39,000 pertussis toxin substrates are increased in surgically denervated dog ventricular myocardium. J Cardiovasc Pharmacol. 1991 Apr; 17(4):568-75. PMID: 1711622.
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    302. Hershberger RE, Feldman AM, Bristow MR. A1-adenosine receptor inhibition of adenylate cyclase in failing and nonfailing human ventricular myocardium. Circulation. 1991 Apr; 83(4):1343-51. PMID: 1901530.
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    303. O'Connell JB, Renlund DG, Hammond EH, Wittwer CT, Yowell RL, DeWitt CW, Jones KW, Gay WA, Menlove RL, Bristow MR. Sensitization to OKT3 monoclonal antibody in heart transplantation: correlation with early allograft loss. J Heart Lung Transplant. 1991 Mar-Apr; 10(2):217-21; discussion 221-2. PMID: 1903303.
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    304. O'Connell JB, Bristow MR, Hammond EH, Menlove RL, Ensley RD, Ratkovec RM, Renlund DG. Antimurine antibody to OKT3 in cardiac transplantation: implications for prophylaxis and retreatment of rejection. Transplant Proc. 1991 Feb; 23(1 Pt 2):1157-9. PMID: 1899154.
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    305. O'Connell JB, Renlund DG, Bristow MR, Hammond EH. Detection of allograft endothelial cells of recipient origin following ABO-compatible, nonidentical cardiac transplantation. Transplantation. 1991 Feb; 51(2):438-42. PMID: 1994540.
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    306. Ensley RD, Hammond EH, Renlund DG, Yowell RL, Bristow MR, DeWitt CW, Menlove RL, Ratkovec RM, O'Connell JB. Clinical manifestations of vascular rejection in cardiac transplantation. Transplant Proc. 1991 Feb; 23(1 Pt 2):1130-2. PMID: 1989167.
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    307. Moore CK, O'Connell JB, Renlund DG, Bristow MR, Hammond EH. Cardiac allograft cellular rejection during OKT3 prophylaxis in the absence of sensitization. Transplant Proc. 1991 Feb; 23(1 Pt 2):1055-8. PMID: 1899151.
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    308. Gilbert EM, O'Connell JB, Bristow MR. Therapy of idiopathic dilated cardiomyopathy with chronic beta-adrenergic blockade. Heart Vessels Suppl. 1991; 6:29-39. PMID: 1687924.
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    309. O'Connell JB, Bristow MR, Rasmussen LG, Ratkovec RM, Gay WA, Jones KW, Renlund DG. Cardiac allograft function with corticosteroid-free maintenance immunosuppression. Circulation. 1990 Nov; 82(5 Suppl):IV318-21. PMID: 2121388.
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    310. Olsen SL, O'Connell JB, Bristow MR, Renlund DG. Methotrexate as an adjunct in the treatment of persistent mild cardiac allograft rejection. Transplantation. 1990 Nov; 50(5):773-5. PMID: 2238053.
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    311. Hammond EH, Wittwer CT, Greenwood J, Knape WA, Yowell RL, Menlove RL, Craven C, Renlund DG, Bristow MR, DeWitt CW, et al. Relationship of OKT3 sensitization and vascular rejection in cardiac transplant patients receiving OKT3 rejection prophylaxis. Transplantation. 1990 Nov; 50(5):776-82. PMID: 2122559.
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    312. Bristow MR. The surgically denervated, transplanted human heart. Circulation. 1990 Aug; 82(2):658-60. PMID: 2372914.
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    313. Bristow MR, Hershberger RE, Port JD, Gilbert EM, Sandoval A, Rasmussen R, Cates AE, Feldman AM. Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation. 1990 Aug; 82(2 Suppl):I12-25. PMID: 2164894.
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    314. Ratkovec RM, Wray RB, Renlund DG, O'Connell JB, Bristow MR, Gay WA, Karwande SV, Doty DB, Millar RC, Menlove RL, et al. Influence of corticosteroid-free maintenance immunosuppression on allograft coronary artery disease after cardiac transplantation. J Thorac Cardiovasc Surg. 1990 Jul; 100(1):6-12. PMID: 2366566.
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    315. Hershberger RE, Wynn JR, Sundberg L, Bristow MR. Mechanism of action of bucindolol in human ventricular myocardium. J Cardiovasc Pharmacol. 1990 Jun; 15(6):959-67. PMID: 1694919.
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    316. Moore CK, Bristow MR, Renlund DG, Rasmussen LG, O'Connell JB. Long-term morbidity of cyclosporine with corticosteroid-free maintenance immunosuppression in cardiac transplantation. Transplant Proc. 1990 Jun; 22(3 Suppl 1):25-9. PMID: 2349736.
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    317. Hammond EH, Watson FS, Bristow MR, O'Connell JB, Gilbert EM, Doty DB, Renlund DG. Fibrinoid necrosis of a temporal artery complicating the treatment of refractory cardiac allograft rejection with murine monoclonal CD3 antibody (OKT3). J Heart Transplant. 1990 May-Jun; 9(3 Pt 1):236-8. PMID: 2113090.
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    318. Renlund DG, O'Connell JB, Bristow MR. Strategies of immunosuppression in cardiac transplantation. Semin Thorac Cardiovasc Surg. 1990 Apr; 2(2):181-8. PMID: 2127901.
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    319. Gilbert EM, Anderson JL, Deitchman D, Yanowitz FG, O'Connell JB, Renlund DG, Bartholomew M, Mealey PC, Larrabee P, Bristow MR. Long-term beta-blocker vasodilator therapy improves cardiac function in idiopathic dilated cardiomyopathy: a double-blind, randomized study of bucindolol versus placebo. Am J Med. 1990 Mar; 88(3):223-9. PMID: 1968710.
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    320. Port JD, Gilbert EM, Larrabee P, Mealey P, Volkman K, Ginsburg R, Hershberger RE, Murray J, Bristow MR. Neurotransmitter depletion compromises the ability of indirect-acting amines to provide inotropic support in the failing human heart. Circulation. 1990 Mar; 81(3):929-38. PMID: 1968367.
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    321. Rasmussen RP, Minobe W, Bristow MR. Calcium antagonist binding sites in failing and nonfailing human ventricular myocardium. Biochem Pharmacol. 1990 Feb 15; 39(4):691-6. PMID: 2154992.
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    322. Woodley SL, Renlund DG, O'Connell JB, Bristow MR. Immunosuppression following cardiac transplantation. Cardiol Clin. 1990 Feb; 8(1):83-96. PMID: 2407363.
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    323. Feldman AM, Bristow MR. The beta-adrenergic pathway in the failing human heart: implications for inotropic therapy. Cardiology. 1990; 77 Suppl 1:1-32. PMID: 1970755.
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    324. Kantrowitz NE, Ellis AK, Bristow MR, Minobe W, Billingham ME, Harrison DC. Histamine mediates myocardial damage by an H1 mechanism independent of coronary blood flow. J Cardiovasc Pharmacol. 1990 Jan; 15(1):82-8. PMID: 1688987.
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    325. Hammond EH, Yowell RL, Nunoda S, Menlove RL, Renlund DG, Bristow MR, Gay WA, Jones KW, O'Connell JB. Vascular (humoral) rejection in heart transplantation: pathologic observations and clinical implications. J Heart Transplant. 1989 Nov-Dec; 8(6):430-43. PMID: 2693662.
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    326. Movsesian MA, Bristow MR, Krall J. Ca2+ uptake by cardiac sarcoplasmic reticulum from patients with idiopathic dilated cardiomyopathy. Circ Res. 1989 Oct; 65(4):1141-4. PMID: 2551528.
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    327. Wittwer CT, Knape WA, Bristow MR, Gilbert EM, Renlund DG, O'Connell JB, DeWitt CW. The quantitative flow cytometric plasma OKT3 assay. Its potential application in cardiac transplantation. Transplantation. 1989 Sep; 48(3):533-5. PMID: 2528852.
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    328. Hershberger RE, Anderson FL, Bristow MR. Vasoactive intestinal peptide receptor in failing human ventricular myocardium exhibits increased affinity and decreased density. Circ Res. 1989 Aug; 65(2):283-94. PMID: 2546693.
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    329. Hegewald MG, O'Connell JB, Renlund DG, Lee HR, Burton NA, Karwande SV, Jones KW, Lassetter JE, Bristow MR. OKT3 monoclonal antibody given for ten versus fourteen days as immunosuppressive prophylaxis in heart transplantation. J Heart Transplant. 1989 Jul-Aug; 8(4):303-9; discussion 309-10. PMID: 2504897.
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    330. Shaddy RE, Mak C, Bristow MR. Comparative in vitro myocardial inotropic effects and in vivo hemodynamic effects of forskolin and isoproterenol in young lambs. Pediatr Res. 1989 Jun; 25(6):580-4. PMID: 2740148.
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    331. Brodde OE, Michel MC, Gordon EP, Sandoval A, Gilbert EM, Bristow MR. Beta-adrenoceptor regulation in the human heart: can it be monitored in circulating lymphocytes? Eur Heart J. 1989 Jun; 10 Suppl B:2-10. PMID: 2553408.
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    332. Bristow MR, Port JD, Hershberger RE, Gilbert EM, Feldman AM. The beta-adrenergic receptor-adenylate cyclase complex as a target for therapeutic intervention in heart failure. Eur Heart J. 1989 Jun; 10 Suppl B:45-54. PMID: 2572420.
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    333. Renlund DG, O'Connell JB, Bristow MR. Early rejection prophylaxis in heart transplantation: is cytolytic therapy necessary? J Heart Transplant. 1989 May-Jun; 8(3):191-3. PMID: 2661767.
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    334. O'Connell JB, Renlund DG, Gay WA, DeWitt CW, Hammond EH, Yowell RL, Jones KW, Karwande SV, Doty DB, Bristow MR. Efficacy of OKT3 retreatment for refractory cardiac allograft rejection. Transplantation. 1989 May; 47(5):788-92. PMID: 2655215.
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    335. Renlund DG, Bristow MR, Crandall BG, Burton NA, Doty DB, Karwande SV, Gay WA, Jones KW, Hegewald MG, Hagan ME, et al. Hypercholesterolemia after heart transplantation: amelioration by corticosteroid-free maintenance immunosuppression. J Heart Transplant. 1989 May-Jun; 8(3):214-9; discussion 219-20. PMID: 2661771.
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    336. Feldman AM, Cates AE, Bristow MR, Van Dop C. Altered expression of alpha-subunits of G proteins in failing human hearts. J Mol Cell Cardiol. 1989 Apr; 21(4):359-65. PMID: 2501499.
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    337. Heilbrunn SM, Shah P, Bristow MR, Valantine HA, Ginsburg R, Fowler MB. Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy. Circulation. 1989 Mar; 79(3):483-90. PMID: 2537158.
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    338. O'Connell JB, Renlund DG, Bristow MR. Cardiac transplantation: emerging role of the internist/cardiologist. J Intern Med. 1989 Mar; 225(3):147-56. PMID: 2649631.
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    339. Bristow MR, Hershberger RE, Port JD, Minobe W, Rasmussen R. Beta 1- and beta 2-adrenergic receptor-mediated adenylate cyclase stimulation in nonfailing and failing human ventricular myocardium. Mol Pharmacol. 1989 Mar; 35(3):295-303. PMID: 2564629.
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    340. Gilbert EM, Eiswirth CC, Mealey PC, Larrabee P, Herrick CM, Bristow MR. Beta-adrenergic supersensitivity of the transplanted human heart is presynaptic in origin. Circulation. 1989 Feb; 79(2):344-9. PMID: 2536597.
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    341. Bristow MR, Minobe W, Rasmussen R, Hershberger RE, Hoffman BB. Alpha-1 adrenergic receptors in the nonfailing and failing human heart. J Pharmacol Exp Ther. 1988 Dec; 247(3):1039-45. PMID: 2849656.
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    342. Bristow MR, Lee HE, Gilbert EM, Renlund DG, Hegewald MG, Hershberger RE, O'Connell JB. Use of enoximone in patients awaiting cardiac transplant. Br J Clin Pract Suppl. 1988 Dec; 64:69-72. PMID: 2978503.
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    343. Renlund DG, Bristow MR, O'Connell JB. Cardiac transplantation--the need for prospective, randomized, controlled investigations. West J Med. 1988 Nov; 149(5):583-5. PMID: 3074558.
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    344. Anderson FL, Kralios AC, Hershberger R, Bristow MR. Effect of vasoactive intestinal peptide on myocardial contractility and coronary blood flow in the dog: comparison with isoproterenol and forskolin. J Cardiovasc Pharmacol. 1988 Sep; 12(3):365-71. PMID: 2464111.
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    345. Anderson FL, Kralios AC, Hershberger R, Bristow MR. Desensitization of myocardial but not coronary VIP receptor-mediated responses in dogs. Am J Physiol. 1988 Sep; 255(3 Pt 2):H601-7. PMID: 2843056.
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    346. Gay WA, O'Connell JG, Burton NA, Karwande SV, Renlund DG, Bristow MR. OKT3 monoclonal antibody in cardiac transplantation. Experience with 102 patients. Ann Surg. 1988 Sep; 208(3):287-90. PMID: 3138951.
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    347. Renlund DG, Bristow MR, Lee HR, O'Connell JB. Medical aspects of cardiac transplantation. J Cardiothorac Anesth. 1988 Aug; 2(4):500-12. PMID: 17171937.
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    348. Feldman AM, Cates AE, Veazey WB, Hershberger RE, Bristow MR, Baughman KL, Baumgartner WA, Van Dop C. Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart. J Clin Invest. 1988 Jul; 82(1):189-97. PMID: 2839545.
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    349. Gilbert EM, Krueger SK, Murray JL, Renlund DG, O'Connell JB, Gay WA, Bristow MR. Echocardiographic evaluation of potential cardiac transplant donors. J Thorac Cardiovasc Surg. 1988 Jun; 95(6):1003-7. PMID: 3287011.
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    350. Bristow MR, Sandoval AB, Gilbert EM, Deisher T, Minobe W, Rasmussen R. Myocardial alpha- and beta-adrenergic receptors in heart failure: is cardiac-derived norepinephrine the regulatory signal? Eur Heart J. 1988 Jun; 9 Suppl H:35-40. PMID: 2844538.
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    351. Yowell RL, Hammond EH, Bristow MR, Watson FS, Renlund DG, O'Connell JB. Acute vascular rejection involving the major coronary arteries of a cardiac allograft. J Heart Transplant. 1988 May-Jun; 7(3):191-7. PMID: 3290402.
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    352. Gilbert EM, O'Connell JB, Hammond ME, Renlund DG, Watson FS, Bristow MR. Treatment of myocarditis with OKT3 monoclonal antibody. Lancet. 1988 Apr 02; 1(8588):759. PMID: 2895275.
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    353. Wittwer CT, Bristow MR, Gilbert EM, Renlund DG, O'Connell JB, DeWitt CW. OKT3 therapy as a cause of high panel-reactive antibodies in serum using standard microcytotoxicity techniques. Transplantation. 1988 Apr; 45(4):832-4. PMID: 3282368.
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    354. Watson FS, O'Connell JB, Amber IJ, Renlund DG, Classen D, Johnston JM, Smith CB, Bristow MR. Treatment of cytomegalovirus pneumonia in heart transplant recipients with 9(1,3-dihydroxy-2-proproxymethyl)-guanine (DHPG). J Heart Transplant. 1988 Mar-Apr; 7(2):102-5. PMID: 2835468.
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    355. Bristow MR. The beta-adrenergic receptor. Configuration, regulation, mechanism of action. Postgrad Med. 1988 Feb 29; Spec No:19-26. PMID: 2894659.
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    356. Bristow MR, Gilbert EM, O'Connell JB, Renlund DG, Watson FS, Hammond E, Lee RG, Menlove R. OKT3 monoclonal antibody in heart transplantation. Am J Kidney Dis. 1988 Feb; 11(2):135-40. PMID: 3277404.
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    357. Lurie KG, Bristow MR, Minobe WA, Masek M, Billingham ME. 6-Hydroxydopamine mediated cardiotoxicity in rabbits. Am J Cardiovasc Pathol. 1988; 2(2):181-91. PMID: 3144992.
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    358. Gilbert EM, Renlund DG, O'Connell JB, Eiswirth CC, Rothstein G, Gay WA, Bristow MR. Immunosuppressive efficacy of vincristine in heart transplantation: a preliminary report. J Heart Transplant. 1987 Nov-Dec; 6(6):369-74. PMID: 3320307.
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    359. Renlund DG, Gilbert EM, O'Connell JB, Gay WA, Jones KW, Burton NA, Doty DB, Karwande SV, Dewitt CW, Menlove RL, Herrick CM, Bristow MR. Age-associated decline in cardiac allograft rejection. Am J Med. 1987 09; 83(3):391-8. PMID: 3310619.
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    360. Gilbert EM, Bristow MR, Mason JW. Acute hemodynamic response to low dose enoximone (MDL 17,043): an oral dose-range study. Am J Cardiol. 1987 Aug 14; 60(5):57C-62C. PMID: 2956870.
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    361. Renlund DG, Bristow MR, Burton NA, Jones KW, Karwande SV, Gay WA. Survival following cardiac transplantation--what are acceptable standards? West J Med. 1987 May; 146(5):627-30. PMID: 3296459.
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    362. Renlund DG, Bristow MR, Lybbert MR, O'Connell JB, Gay WA. Medicare-designated centers for cardiac transplantation. N Engl J Med. 1987 Apr 02; 316(14):873-6. PMID: 3547136.
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    363. Gilbert EM, Eiswirth CC, Renlund DG, Menlove RL, DeWitt CW, Freedman LA, Herrick CM, Gay WA, Bristow MR. Use of Orthoclone OKT3 monoclonal antibody in cardiac transplantation: early experience with rejection prophylaxis and treatment of refractory rejection. Transplant Proc. 1987 Apr; 19(2 Suppl 1):45-53. PMID: 3105140.
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    364. Renlund DG, O'Connell JB, Gilbert EM, Watson FS, Bristow MR. Feasibility of discontinuation of corticosteroid maintenance therapy in heart transplantation. J Heart Transplant. 1987 Mar-Apr; 6(2):71-8. PMID: 3305832.
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    365. Gilbert EM, Dewitt CW, Eiswirth CC, Renlund DG, Menlove RL, Freedman LA, Herrick CM, Gay WA, Bristow MR. Treatment of refractory cardiac allograft rejection with OKT3 monoclonal antibody. Am J Med. 1987 Feb; 82(2):202-6. PMID: 3544838.
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    366. Bristow MR, Ginsburg R, Gilbert EM, Hershberger RE. Heterogeneous regulatory changes in cell surface membrane receptors coupled to a positive inotropic response in the failing human heart. Basic Res Cardiol. 1987; 82 Suppl 2:369-76. PMID: 2821984.
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    367. Fowler MB, Laser JA, Hopkins GL, Minobe W, Bristow MR. Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response. Circulation. 1986 Dec; 74(6):1290-302. PMID: 3022962.
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    368. Bristow MR, Ginsburg R, Umans V, Fowler M, Minobe W, Rasmussen R, Zera P, Menlove R, Shah P, Jamieson S, et al. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res. 1986 Sep; 59(3):297-309. PMID: 2876788.
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    369. Bristow MR, Ginsburg R. Beta 2 receptors on myocardial cells in human ventricular myocardium. Am J Cardiol. 1986 Apr 25; 57(12):3F-6F. PMID: 3010694.
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    370. Freter CE, Lee TC, Billingham ME, Chak L, Bristow MR. Doxorubicin cardiac toxicity manifesting seven years after treatment. Case report and review. Am J Med. 1986 Mar; 80(3):483-5. PMID: 3513562.
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    371. Schroeder JS, Beier-Scott L, Ginsburg R, Bristow MR, McAuley BJ. Efficacy of diltiazem for medically refractory stable angina: long-term follow-up. Clin Cardiol. 1985 Sep; 8(9):480-5. PMID: 2864152.
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    372. Bristow MR, Kantrowitz NE, Ginsburg R, Fowler MB. Beta-adrenergic function in heart muscle disease and heart failure. J Mol Cell Cardiol. 1985 Jul; 17 Suppl 2:41-52. PMID: 2863387.
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    373. Fowler MB, Bristow MR. Rationale for beta-adrenergic blocking drugs in cardiomyopathy. Am J Cardiol. 1985 Apr 26; 55(10):120D-124D. PMID: 2859789.
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    374. Kantrowitz NE, Bristow MR. Cardiotoxicity of antitumor agents. Prog Cardiovasc Dis. 1984 Nov-Dec; 27(3):195-200. PMID: 6387802.
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    375. Bristow MR. The adrenergic nervous system in heart failure. N Engl J Med. 1984 Sep 27; 311(13):850-1. PMID: 6472388.
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    376. Ginsburg R, Bristow MR, Davis K. Receptor mechanisms in the human epicardial coronary artery. Heterogeneous pharmacological response to histamine and carbachol. Circ Res. 1984 Sep; 55(3):416-21. PMID: 6467531.
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    377. Bristow MR, Ginsburg R, Strosberg A, Montgomery W, Minobe W. Pharmacology and inotropic potential of forskolin in the human heart. J Clin Invest. 1984 Jul; 74(1):212-23. PMID: 6330174.
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    378. Bristow MR, Ginsburg R, Laser JA, McAuley BJ, Minobe W. Tissue response selectivity of calcium antagonists is not due to heterogeneity of [3H]-nitrendipine binding sites. Br J Pharmacol. 1984 Jun; 82(2):309-20. PMID: 6329392.
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    379. Bristow MR. Myocardial beta-adrenergic receptor downregulation in heart failure. Int J Cardiol. 1984 May; 5(5):648-52. PMID: 6325351.
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    380. Tsujimoto G, Bristow MR, Hoffman BB. Identification of alpha 1 adrenergic receptors in rabbit aorta with [125I] BE2254. Life Sci. 1984 Feb 13; 34(7):639-46. PMID: 6321870.
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    381. Ginsburg R, Bristow MR, Davis K, Dibiase A, Billingham ME. Quantitative pharmacologic responses of normal and atherosclerotic isolated human epicardial coronary arteries. Circulation. 1984 Feb; 69(2):430-40. PMID: 6690108.
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    382. Bristow MR, Billingham ME, Mason JW. Adriamycin cardiotoxicity. Am J Cardiol. 1984 Jan 01; 53(1):263-4. PMID: 6691272.
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    383. Torti FM, Bristow MR, Howes AE, Aston D, Stockdale FE, Carter SK, Kohler M, Brown BW, Billingham ME. Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule. Assessment by endomyocardial biopsy. Ann Intern Med. 1983 Dec; 99(6):745-9. PMID: 6651020.
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    384. McKillop JH, Bristow MR, Goris ML, Billingham ME, Bockemuehl K. Sensitivity and specificity of radionuclide ejection fractions in doxorubicin cardiotoxicity. Am Heart J. 1983 Nov; 106(5 Pt 1):1048-56. PMID: 6637763.
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    385. Bristow MR, Kantrowitz NE, Harrison WD, Minobe WA, Sageman WS, Billingham ME. Mediation of subacute anthracycline cardiotoxicity in rabbits by cardiac histamine release. J Cardiovasc Pharmacol. 1983 Nov-Dec; 5(6):913-9. PMID: 6196562.
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    386. Ginsburg R, Bristow MR, Billingham ME, Stinson EB, Schroeder JS, Harrison DC. Study of the normal and failing isolated human heart: decreased response of failing heart to isoproterenol. Am Heart J. 1983 Sep; 106(3):535-40. PMID: 6308994.
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    387. Lurie KG, Bristow MR, Reitz BA. Increased beta-adrenergic receptor density in an experimental model of cardiac transplantation. J Thorac Cardiovasc Surg. 1983 Aug; 86(2):195-201. PMID: 6308358.
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    388. Schroeder JS, Lamb IH, Bristow MR, Ginsburg R, Hung J, McAuley BJ. Prevention of cardiovascular events in variant angina by long-term diltiazem therapy. J Am Coll Cardiol. 1983 Jun; 1(6):1507-11. PMID: 6853903.
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    389. Ginsburg R, Esserman LJ, Bristow MR. Myocardial performance and extracellular ionized calcium in a severely failing human heart. Ann Intern Med. 1983 May; 98(5 Pt 1):603-6. PMID: 6133487.
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    390. Bristow MR. Toxic cardiomyopathy due to doxorubicin. Hosp Pract (Off Ed). 1982 Dec; 17(12):101-8, 110-1. PMID: 6815051.
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    391. Kantrowitz NE, Bristow MR, Minobe WA, Billingham ME, Harrison DC. Histamine-mediated myocardial damage in rabbits. J Mol Cell Cardiol. 1982 Sep; 14(9):551-5. PMID: 7175954.
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    392. Bristow MR, Ginsburg R, Minobe W, Cubicciotti RS, Sageman WS, Lurie K, Billingham ME, Harrison DC, Stinson EB. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med. 1982 Jul 22; 307(4):205-11. PMID: 6283349.
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    393. Bristow MR, Lopez MB, Mason JW, Billingham ME, Winchester MA. Efficacy and cost of cardiac monitoring in patients receiving doxorubicin. Cancer. 1982 Jul 01; 50(1):32-41. PMID: 7083125.
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    394. Lurie KG, Billingham ME, Masek MA, Ginsburg R, Bristow MR, Harrison D, Reitz BA. Ultrastructural and functional studies on prolonged myocardial preservation in an experimental heart transplant model. J Thorac Cardiovasc Surg. 1982 Jul; 84(1):122-9. PMID: 7045539.
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    395. Bristow MR, Cubicciotti R, Ginsburg R, Stinson EB, Johnson C. Histamine-mediated adenylate cyclase stimulation in human myocardium. Mol Pharmacol. 1982 May; 21(3):671-9. PMID: 6125879.
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    396. Clusin WT, Bristow MR, Baim DS, Schroeder JS, Jaillon P, Brett P, Harrison DC. The effects of diltiazem and reduced serum ionized calcium on ischemic ventricular fibrillation in the dog. Circ Res. 1982 Apr; 50(4):518-26. PMID: 7067059.
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    397. Bristow MR, Ginsburg R, Kantrowitz NE, Baim DS, Rosenbaum JT. Coronary spasm associated with urticaria: report of a case mimicking anaphylaxis. Clin Cardiol. 1982 Mar; 5(3):238-40. PMID: 7083649.
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    398. Schroeder JS, Lamb IH, Ginsburg R, Bristow MR, Hung J. Diltiazem for long-term therapy of coronary arterial spasm. Am J Cardiol. 1982 Feb 18; 49(3):533-7. PMID: 7058764.
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    399. Clusin WT, Bristow MR, Karagueuzian HS, Katzung BG, Schroeder JS. Do calcium-dependent ionic currents mediate ischemic ventricular fibrillation? Am J Cardiol. 1982 Feb 18; 49(3):606-12. PMID: 6277181.
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    400. Bristow MR, Ginsburg R, Harrison DC. Histamine and the human heart: the other receptor system. Am J Cardiol. 1982 Jan; 49(1):249-51. PMID: 7032271.
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    401. Ginsburg R, Bristow MR, Kantrowitz N, Baim DS, Harrison DC. Histamine provocation of clinical coronary artery spasm: implications concerning pathogenesis of variant angina pectoris. Am Heart J. 1981 Nov; 102(5):819-22. PMID: 6795908.
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    402. Bristow MR, Mason JW, Billingham ME, Daniels JR. Dose-effect and structure-function relationships in doxorubicin cardiomyopathy. Am Heart J. 1981 Oct; 102(4):709-18. PMID: 7282516.
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    403. Ginsburg R, Stinson EB, Bristow MR, Schroeder JS. Coronary-artery spasm after revascularization. N Engl J Med. 1981 Sep 17; 305(12):699. PMID: 6973694.
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    404. Bristow MR, Minobe WA, Billingham ME, Marmor JB, Johnson GA, Ishimoto BM, Sageman WS, Daniels JR. Anthracycline-associated cardiac and renal damage in rabbits. Evidence for mediation by vasoactive substances. Lab Invest. 1981 Aug; 45(2):157-68. PMID: 6167794.
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    405. Bristow MR, Sageman WS, Scott RH, Billingham ME, Bowden RE, Kernoff RS, Snidow GH, Daniels JR. Acute and chronic cardiovascular effects of doxorubicin in the dog: the cardiovascular pharmacology of drug-induced histamine release. J Cardiovasc Pharmacol. 1980 Sep-Oct; 2(5):487-515. PMID: 6157945.
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    406. Ginsburg R, Bristow MR, Harrison DC, Stinson EB. Studies with isolated human coronary arteries. Some general observations, potential mediators of spasm, role of calcium antagonists. Chest. 1980 Jul; 78(1 Suppl):180-6. PMID: 6772384.
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    407. Ginsburg R, Bristow MR, Stinson EB, Harrison DC. Histamine receptors in the human heart. Life Sci. 1980 Jun 30; 26(26):2245-9. PMID: 6105606.
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    408. Bristow MR. Testing for doxorubicin cardiotoxicity. N Engl J Med. 1979 Jun 14; 300(24):1393. PMID: 440372.
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    409. Bristow MR, Thompson PD, Martin RP, Mason JW, Billingham ME, Harrison DC. Early anthracycline cardiotoxicity. Am J Med. 1978 Nov; 65(5):823-32. PMID: 707541.
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    410. Mason JW, Bristow MR, Billingham ME, Daniels JR. Invasive and noninvasive methods of assessing adriamycin cardiotoxic effects in man: superiority of histopathologic assessment using endomyocardial biopsy. Cancer Treat Rep. 1978 Jun; 62(6):857-64. PMID: 667859.
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    411. Billingham ME, Mason JW, Bristow MR, Daniels JR. Anthracycline cardiomyopathy monitored by morphologic changes. Cancer Treat Rep. 1978 Jun; 62(6):865-72. PMID: 667860.
      View in: PubMed
    412. Bristow MR, Billingham ME, Mason JW, Daniels JR. Clinical spectrum of anthracycline antibiotic cardiotoxicity. Cancer Treat Rep. 1978 Jun; 62(6):873-9. PMID: 667861.
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    413. Bristow MR, Mason JW, Billingham ME, Daniels JR. Doxorubicin cardiomyopathy: evaluation by phonocardiography, endomyocardial biopsy, and cardiac catheterization. Ann Intern Med. 1978 Feb; 88(2):168-75. PMID: 626445.
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    414. Bristow MR, Daniels JR, Kernoff RS, Harrison DC. Effect of D600, practolol, and alterations in magnesium on ionized calcium concentration-response relationships in the intact dog heart. Circ Res. 1977 Oct; 41(4):574-81. PMID: 902364.
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    415. Bristow MR, Schwartz HD, Binetti G, Harrison DC, Daniels JR. Ionized calcium and the heart. Elucidation of in vivo concentration-response relationships in the open-chest dog. Circ Res. 1977 Oct; 41(4):565-74. PMID: 902363.
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    416. Billingham ME, Bristow MR, Glatstein E, Mason JW, Masek MA, Daniels JR. Adriamycin cardiotoxicity: endomyocardial biopsy evidence of enhancement by irradiation. Am J Surg Pathol. 1977 Mar; 1(1):17-23. PMID: 602969.
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    417. Green RD, Lefever GS, Sheys EM, Bristow M. On the specificity of alpha adrenergic receptor labeling by 14C-dibenamine. J Pharmacol Exp Ther. 1973 Dec; 187(3):524-8. PMID: 4149130.
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    418. Bristow M, Green RD. A quantitative study of beta-adrenergic receptors in rabbit atria. Eur J Pharmacol. 1970 Sep 01; 12(1):120-3. PMID: 4394343.
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    419. Bristow M. Vasodilation in treatment of hypertension. N Engl J Med. 1970 May 07; 282(19):1102. PMID: 4392413.
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    420. Bristow M, Sherrod TR, Green RD. Analysis of beta receptor drug interactions in isolated rabbit atrium, aorta, stomach and trachea. J Pharmacol Exp Ther. 1970 Jan; 171(1):52-61. PMID: 4391468.
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