 Connection
Hong Chu to Lung
This is a "connection" page, showing publications Hong Chu has written about Lung.
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Connection Strength |
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3.541 |
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Schaunaman N, Cervantes D, Ferrington DA, Chu HW. Degradation of IL-4Ralpha by Immunoproteasome: implication in airway type 2 inflammation and hyperresponsiveness. Front Immunol. 2025; 16:1501898.
Score: 0.347
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Agraval H, Gao J, Schaunaman N, Hua H, Vandivier RW, Numata M, Day BJ, Chu HW. Toll-Interacting Protein Down-Regulation by Cigarette Smoke Exposure Impairs Human Lung Defense against Influenza A Virus Infection. Am J Pathol. 2025 06; 195(6):1124-1140.
Score: 0.347
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Jiang D, Wenzel SE, Wu Q, Bowler RP, Schnell C, Chu HW. Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria. PLoS One. 2013; 8(5):e64689.
Score: 0.153
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Wu Q, Jiang D, Chu HW. Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin over-expression. Innate Immun. 2012 Aug; 18(4):617-26.
Score: 0.139
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Gally F, Minor MN, Smith SK, Case SR, Chu HW. Heat shock factor 1 protects against lung mycoplasma pneumoniae infection in mice. J Innate Immun. 2012; 4(1):59-68.
Score: 0.137
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Thaikoottathil J, Chu HW. MAPK/AP-1 activation mediates TLR2 agonist-induced SPLUNC1 expression in human lung epithelial cells. Mol Immunol. 2011 Dec; 49(3):415-22.
Score: 0.136
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Wu Q, Jiang D, Minor MN, Martin RJ, Chu HW. In vivo function of airway epithelial TLR2 in host defense against bacterial infection. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L579-86.
Score: 0.130
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Simon GC, Martin RJ, Smith S, Thaikoottathil J, Bowler RP, Barenkamp SJ, Chu HW. Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence. Am J Respir Cell Mol Biol. 2011 May; 44(5):606-13.
Score: 0.130
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Nouri HR, Schaunaman N, Kraft M, Numata M, Vercelli D, Chu HW. Tollip deficiency enhances mitophagy and reduces STING activation in influenza A virus-infected mice. J Immunol. 2025 Jul 01; 214(7):1741-1753.
Score: 0.089
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Chu HW, Jeyaseelan S, Rino JG, Voelker DR, Wexler RB, Campbell K, Harbeck RJ, Martin RJ. TLR2 signaling is critical for Mycoplasma pneumoniae-induced airway mucin expression. J Immunol. 2005 May 01; 174(9):5713-9.
Score: 0.088
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Gao J, Zhao D, Nouri HR, Chu HW, Huang H. Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation. Immunol Rev. 2025 05; 331(1):e70026.
Score: 0.088
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Chu HW, Rino JG, Wexler RB, Campbell K, Harbeck RJ, Martin RJ. Mycoplasma pneumoniae infection increases airway collagen deposition in a murine model of allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2005 Jul; 289(1):L125-33.
Score: 0.087
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Schaunaman N, Nichols T, Cervantes D, Hartsoe P, Ferrington DA, Chu HW. The Effect of a TLR3 Agonist on Airway Allergic Inflammation and Viral Infection in Immunoproteasome-Deficient Mice. Viruses. 2024 08 29; 16(9).
Score: 0.084
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Schaunaman N, Cervantes D, Nichols T, Numata M, Ledford JG, Kraft M, Chu HW. Cooperation of immune regulators Tollip and surfactant protein A inhibits influenza A virus infection in mice. Respir Res. 2024 May 03; 25(1):193.
Score: 0.082
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Chu HW, Campbell JA, Rino JG, Harbeck RJ, Martin RJ. Inhaled fluticasone propionate reduces concentration of Mycoplasma pneumoniae, inflammation, and bronchial hyperresponsiveness in lungs of mice. J Infect Dis. 2004 Mar 15; 189(6):1119-27.
Score: 0.081
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Crue T, Lee GY, Peng JY, Schaunaman N, Agraval H, Day BJ, Dimasuay KG, Cervantes D, Nouri H, Nichols T, Hartsoe P, Numata M, Petrache I, Chu HW. Single cell RNA-sequencing of human precision-cut lung slices: A novel approach to study the effect of vaping and viral infection on lung health. Innate Immun. 2023 07; 29(5):61-70.
Score: 0.077
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Wenzel SE, Balzar S, Cundall M, Chu HW. Subepithelial basement membrane immunoreactivity for matrix metalloproteinase 9: association with asthma severity, neutrophilic inflammation, and wound repair. J Allergy Clin Immunol. 2003 Jun; 111(6):1345-52.
Score: 0.077
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Agraval H, Crue T, Schaunaman N, Numata M, Day BJ, Chu HW. Electronic Cigarette Exposure Increases the Severity of Influenza a Virus Infection via TRAIL Dysregulation in Human Precision-Cut Lung Slices. Int J Mol Sci. 2023 Feb 21; 24(5).
Score: 0.075
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Wenzel SE, Trudeau JB, Barnes S, Zhou X, Cundall M, Westcott JY, McCord K, Chu HW. TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts. J Immunol. 2002 Oct 15; 169(8):4613-9.
Score: 0.073
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Agraval H, Chu HW. Lung Organoids in Smoking Research: Current Advances and Future Promises. Biomolecules. 2022 10 12; 12(10).
Score: 0.073
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Dimasuay KG, Schaunaman N, Berg B, Cervantes D, Kruger E, Heppner FL, Ferrington DA, Chu HW. Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection. Sci Rep. 2022 08 25; 12(1):14507.
Score: 0.073
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Schaunaman N, Dimasuay KG, Cervantes D, Li L, Numata M, Kraft M, Chu HW. Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways. J Innate Immun. 2023; 15(1):67-77.
Score: 0.072
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Schaunaman N, Crue T, Cervantes D, Schweitzer K, Robbins H, Day BJ, Numata M, Petrache I, Chu HW. Electronic cigarette vapor exposure exaggerates the pro-inflammatory response during influenza A viral infection in human distal airway epithelium. Arch Toxicol. 2022 08; 96(8):2319-2328.
Score: 0.072
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Tassew D, Fort S, Mebratu Y, McDonald J, Chu HW, Petersen H, Tesfaigzi Y. Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in Tp53. Environ Health Perspect. 2022 01; 130(1):17010.
Score: 0.070
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Stancil IT, Michalski JE, Davis-Hall D, Chu HW, Park JA, Magin CM, Yang IV, Smith BJ, Dobrinskikh E, Schwartz DA. Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional. Nat Commun. 2021 07 27; 12(1):4566.
Score: 0.067
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Summers ME, Richmond BW, Menon S, Sheridan RM, Kropski JA, Majka SA, Taketo MM, Bastarache JA, West JD, De Langhe S, Geraghty P, Klemm DJ, Chu HW, Friedman RS, Tao YK, Foronjy RF, Majka SM. Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling. FASEB J. 2020 08; 34(8):10267-10285.
Score: 0.062
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Dimasuay KG, Schaunaman N, Martin RJ, Pavelka N, Kolakowski C, Gottlieb RA, Holguin F, Chu HW. Parkin, an E3 ubiquitin ligase, enhances airway mitochondrial DNA release and inflammation. Thorax. 2020 09; 75(9):717-724.
Score: 0.062
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Jiang D, Matsuda J, Berman R, Schaefer N, Stevenson C, Gross J, Zhang B, Sanchez A, Li L, Chu HW. A novel mouse model of conditional IRAK-M deficiency in myeloid cells: application in lung Pseudomonas aeruginosa infection. Innate Immun. 2017 02; 23(2):206-215.
Score: 0.049
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Wu Q, Jiang D, Matsuda JL, Ternyak K, Zhang B, Chu HW. Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production. Am J Respir Cell Mol Biol. 2016 09; 55(3):429-38.
Score: 0.048
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Jiang D, Persinger R, Wu Q, Gross A, Chu HW. a1-Antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice. Respir Res. 2013 Nov 09; 14:122.
Score: 0.040
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Kratzer A, Chu HW, Salys J, Moumen Z, Leberl M, Bowler R, Cool C, Zamora M, Taraseviciene-Stewart L. Endothelial cell adhesion molecule CD146: implications for its role in the pathogenesis of COPD. J Pathol. 2013 Aug; 230(4):388-98.
Score: 0.039
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Numata M, Grinkova YV, Mitchell JR, Chu HW, Sligar SG, Voelker DR. Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung. Int J Nanomedicine. 2013; 8:1417-27.
Score: 0.038
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Wu Q, Case SR, Minor MN, Jiang D, Martin RJ, Bowler RP, Wang J, Hartney J, Karimpour-Fard A, Chu HW. A novel function of MUC18: amplification of lung inflammation during bacterial infection. Am J Pathol. 2013 Mar; 182(3):819-27.
Score: 0.037
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Thaikoottathil JV, Martin RJ, Di PY, Minor M, Case S, Zhang B, Zhang G, Huang H, Chu HW. SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):253-60.
Score: 0.035
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Gally F, Di YP, Smith SK, Minor MN, Liu Y, Bratton DL, Frasch SC, Michels NM, Case SR, Chu HW. SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice. Am J Pathol. 2011 May; 178(5):2159-67.
Score: 0.033
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Hartney JM, Brown J, Chu HW, Chang LY, Pelanda R, Torres RM. Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity. Am J Pathol. 2010 Mar; 176(3):1157-68.
Score: 0.030
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Kariya C, Chu HW, Huang J, Leitner H, Martin RJ, Day BJ. Mycoplasma pneumoniae infection and environmental tobacco smoke inhibit lung glutathione adaptive responses and increase oxidative stress. Infect Immun. 2008 Oct; 76(10):4455-62.
Score: 0.027
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Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, Chu HW. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect. 2007 Jan; 9(1):78-86.
Score: 0.025
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Chu HW, Breed R, Rino JG, Harbeck RJ, Sills MR, Martin RJ. Repeated respiratory Mycoplasma pneumoniae infections in mice: effect of host genetic background. Microbes Infect. 2006 Jun; 8(7):1764-72.
Score: 0.023
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Lewis CC, Chu HW, Westcott JY, Tucker A, Langmack EL, Sutherland ER, Kraft M. Airway fibroblasts exhibit a synthetic phenotype in severe asthma. J Allergy Clin Immunol. 2005 Mar; 115(3):534-40.
Score: 0.022
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Balzar S, Chu HW, Strand M, Wenzel S. Relationship of small airway chymase-positive mast cells and lung function in severe asthma. Am J Respir Crit Care Med. 2005 Mar 01; 171(5):431-9.
Score: 0.021
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Choi HS, Rai PR, Chu HW, Cool C, Chan ED. Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med. 2002 Jul 15; 166(2):178-86.
Score: 0.018
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Berman R, Min E, Huang J, Kopf K, Downey GP, Riemondy K, Smith HA, Rose CS, Seibold MA, Chu HW, Day BJ. Single-Cell RNA Sequencing Reveals a Unique Monocyte Population in Bronchoalveolar Lavage Cells of Mice Challenged With Afghanistan Particulate Matter and Allergen. Toxicol Sci. 2021 08 03; 182(2):297-309.
Score: 0.017
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Younis US, Chu HW, Kraft M, Ledford JG. A 20-Mer Peptide Derived from the Lectin Domain of SP-A2 Decreases Tumor Necrosis Factor Alpha Production during Mycoplasma pneumoniae Infection. Infect Immun. 2020 08 19; 88(9).
Score: 0.016
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Mishra R, Foster D, Vasu VT, Thaikoottathil JV, Kosmider B, Chu HW, Bowler RP, Finigan JH. Cigarette Smoke Induces Human Epidermal Receptor 2-Dependent Changes in Epithelial Permeability. Am J Respir Cell Mol Biol. 2016 06; 54(6):853-64.
Score: 0.012
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Gould NS, Min E, Huang J, Chu HW, Good J, Martin RJ, Day BJ. Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement. Toxicol Sci. 2015 Oct; 147(2):466-74.
Score: 0.011
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Liu Y, Di ME, Chu HW, Liu X, Wang L, Wenzel S, Di YP. Increased susceptibility to pulmonary Pseudomonas infection in Splunc1 knockout mice. J Immunol. 2013 Oct 15; 191(8):4259-68.
Score: 0.010
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Gould NS, Min E, Gauthier S, Chu HW, Martin R, Day BJ. Aging adversely affects the cigarette smoke-induced glutathione adaptive response in the lung. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1114-22.
Score: 0.008
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Jeyaseelan S, Chu HW, Young SK, Freeman MW, Worthen GS. Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury. Infect Immun. 2005 Mar; 73(3):1754-63.
Score: 0.005
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Jeyaseelan S, Chu HW, Young SK, Worthen GS. Transcriptional profiling of lipopolysaccharide-induced acute lung injury. Infect Immun. 2004 Dec; 72(12):7247-56.
Score: 0.005
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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