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Connection

Theodore Randolph to Proteins

This is a "connection" page, showing publications Theodore Randolph has written about Proteins.

 
Connection Strength
  
 
 
4.163
  
  1. Witeof AE, Daniels AL, Rea LT, Movafaghi S, Kurtz K, Davis M, Eveland RW, Calderon CP, Randolph TW. Machine Learning and Accelerated Stress Approaches to Differentiate Potential Causes of Aggregation in Polyclonal Antibody Formulations During Shipping. J Pharm Sci. 2021 07; 110(7):2743-2752.
    View in: PubMed
    Score: 0.469
  2. Wu H, Chisholm CF, Puryear M, Movafaghi S, Smith SD, Pokhilchuk Y, Lengsfeld CS, Randolph TW. Container Surfaces Control Initiation of Cavitation and Resulting Particle Formation in Protein Formulations After Application of Mechanical Shock. J Pharm Sci. 2020 03; 109(3):1270-1280.
    View in: PubMed
    Score: 0.430
  3. Calderon CP, Daniels AL, Randolph TW. Deep Convolutional Neural Network Analysis of Flow Imaging Microscopy Data to Classify Subvisible Particles in Protein Formulations. J Pharm Sci. 2018 04; 107(4):999-1008.
    View in: PubMed
    Score: 0.376
  4. Gerhardt A, Mcgraw NR, Schwartz DK, Bee JS, Carpenter JF, Randolph TW. Protein aggregation and particle formation in prefilled glass syringes. J Pharm Sci. 2014 Jun; 103(6):1601-12.
    View in: PubMed
    Score: 0.291
  5. Randolph TW. The two faces of His-tag: immune response versus ease of protein purification. Biotechnol J. 2012 Jan; 7(1):18-9.
    View in: PubMed
    Score: 0.249
  6. Ludwig DB, Carpenter JF, Hamel JB, Randolph TW. Protein adsorption and excipient effects on kinetic stability of silicone oil emulsions. J Pharm Sci. 2010 Apr; 99(4):1721-33.
    View in: PubMed
    Score: 0.220
  7. Alford JR, Kendrick BS, Carpenter JF, Randolph TW. Measurement of the second osmotic virial coefficient for protein solutions exhibiting monomer-dimer equilibrium. Anal Biochem. 2008 Jun 15; 377(2):128-33.
    View in: PubMed
    Score: 0.191
  8. Randolph TW, Yasui Y. Multiscale processing of mass spectrometry data. Biometrics. 2006 Jun; 62(2):589-97.
    View in: PubMed
    Score: 0.169
  9. Carpenter JF, Manning MC, Randolph TW. Long-term storage of proteins. Curr Protoc Protein Sci. 2002 May; Chapter 4:Unit 4.6.
    View in: PubMed
    Score: 0.127
  10. Randolph TW, Seefeldt M, Carpenter JF. High hydrostatic pressure as a tool to study protein aggregation and amyloidosis. Biochim Biophys Acta. 2002 Mar 25; 1595(1-2):224-34.
    View in: PubMed
    Score: 0.126
  11. Calderon CP, Ripple DC, Srinivasan C, Ma Y, Carrier MJ, Randolph TW, O'Connor TF. Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy. Pharm Res. 2022 Feb; 39(2):263-279.
    View in: PubMed
    Score: 0.125
  12. Carpenter JF, Chang BS, Garzon-Rodriguez W, Randolph TW. Rational design of stable lyophilized protein formulations: theory and practice. Pharm Biotechnol. 2002; 13:109-33.
    View in: PubMed
    Score: 0.124
  13. Randolph TW, Jones LS. Surfactant-protein interactions. Pharm Biotechnol. 2002; 13:159-75.
    View in: PubMed
    Score: 0.124
  14. Heller MC, Carpenter JF, Randolph TW. Application of a thermodynamic model to the prediction of phase separations in freeze-concentrated formulations for protein lyophilization. Arch Biochem Biophys. 1999 Mar 15; 363(2):191-201.
    View in: PubMed
    Score: 0.102
  15. Carpenter JF, Kendrick BS, Chang BS, Manning MC, Randolph TW. Inhibition of stress-induced aggregation of protein therapeutics. Methods Enzymol. 1999; 309:236-55.
    View in: PubMed
    Score: 0.101
  16. Nejadnik MR, Randolph TW, Volkin DB, Sch?neich C, Carpenter JF, Crommelin DJA, Jiskoot W. Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues. J Pharm Sci. 2018 08; 107(8):2013-2019.
    View in: PubMed
    Score: 0.096
  17. Randolph TW. Phase separation of excipients during lyophilization: effects on protein stability. J Pharm Sci. 1997 Nov; 86(11):1198-203.
    View in: PubMed
    Score: 0.093
  18. Heller MC, Carpenter JF, Randolph TW. Manipulation of lyophilization-induced phase separation: implications for pharmaceutical proteins. Biotechnol Prog. 1997 Sep-Oct; 13(5):590-6.
    View in: PubMed
    Score: 0.092
  19. Carpenter JF, Pikal MJ, Chang BS, Randolph TW. Rational design of stable lyophilized protein formulations: some practical advice. Pharm Res. 1997 Aug; 14(8):969-75.
    View in: PubMed
    Score: 0.092
  20. McUmber AC, Randolph TW, Schwartz DK. Electrostatic Interactions Influence Protein Adsorption (but Not Desorption) at the Silica-Aqueous Interface. J Phys Chem Lett. 2015 Jul 02; 6(13):2583-7.
    View in: PubMed
    Score: 0.079
  21. Holm LS, Mcumber A, Rasmussen JE, Obiols-Rabasa M, Thulstrup PW, Kasimova MR, Randolph TW, van de Weert M. The effect of protein PEGylation on physical stability in liquid formulation. J Pharm Sci. 2014 Oct; 103(10):3043-54.
    View in: PubMed
    Score: 0.075
  22. Izutsu K, Yomota C, Okuda H, Kawanishi T, Randolph TW, Carpenter JF. Impact of heat treatment on miscibility of proteins and disaccharides in frozen solutions. Eur J Pharm Biopharm. 2013 Oct; 85(2):177-83.
    View in: PubMed
    Score: 0.068
  23. Jiskoot W, Randolph TW, Volkin DB, Middaugh CR, Sch?neich C, Winter G, Friess W, Crommelin DJ, Carpenter JF. Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. J Pharm Sci. 2012 Mar; 101(3):946-54.
    View in: PubMed
    Score: 0.062
  24. Bee JS, Randolph TW, Carpenter JF, Bishop SM, Dimitrova MN. Effects of surfaces and leachables on the stability of biopharmaceuticals. J Pharm Sci. 2011 Oct; 100(10):4158-70.
    View in: PubMed
    Score: 0.059
  25. Gabrielson JP, Arthur KK, Kendrick BS, Randolph TW, Stoner MR. Common excipients impair detection of protein aggregates during sedimentation velocity analytical ultracentrifugation. J Pharm Sci. 2009 Jan; 98(1):50-62.
    View in: PubMed
    Score: 0.051
  26. Katayama DS, Carpenter JF, Manning MC, Randolph TW, Setlow P, Menard KP. Characterization of amorphous solids with weak glass transitions using high ramp rate differential scanning calorimetry. J Pharm Sci. 2008 Feb; 97(2):1013-24.
    View in: PubMed
    Score: 0.047
  27. Chi EY, Krishnan S, Randolph TW, Carpenter JF. Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. Pharm Res. 2003 Sep; 20(9):1325-36.
    View in: PubMed
    Score: 0.035
  28. Kim YS, Jones LS, Dong A, Kendrick BS, Chang BS, Manning MC, Randolph TW, Carpenter JF. Effects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteins. Protein Sci. 2003 Jun; 12(6):1252-61.
    View in: PubMed
    Score: 0.034
  29. Bam NB, Randolph TW, Cleland JL. Stability of protein formulations: investigation of surfactant effects by a novel EPR spectroscopic technique. Pharm Res. 1995 Jan; 12(1):2-11.
    View in: PubMed
    Score: 0.019
  30. Serno T, Carpenter JF, Randolph TW, Winter G. Inhibition of agitation-induced aggregation of an IgG-antibody by hydroxypropyl-beta-cyclodextrin. J Pharm Sci. 2010 Mar; 99(3):1193-206.
    View in: PubMed
    Score: 0.014
  31. Vessely C, Estey T, Randolph TW, Henderson I, Nayar R, Carpenter JF. Effects of solution conditions and surface chemistry on the adsorption of three recombinant botulinum neurotoxin antigens to aluminum salt adjuvants. J Pharm Sci. 2007 Sep; 96(9):2375-89.
    View in: PubMed
    Score: 0.012
  32. Stoner MR, Fischer N, Nixon L, Buckel S, Benke M, Austin F, Randolph TW, Kendrick BS. Protein-solute interactions affect the outcome of ultrafiltration/diafiltration operations. J Pharm Sci. 2004 Sep; 93(9):2332-42.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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