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Connection

Theodore Randolph to Chemistry, Pharmaceutical

This is a "connection" page, showing publications Theodore Randolph has written about Chemistry, Pharmaceutical.

 
Connection Strength
  
 
 
4.032
  
  1. Wu H, Randolph TW. Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations. J Pharm Sci. 2019 03; 108(3):1110-1116.
    View in: PubMed
    Score: 0.591
  2. Maddux NR, Daniels AL, Randolph TW. Microflow Imaging Analyses Reflect Mechanisms of Aggregate Formation: Comparing Protein Particle Data Sets Using the Kullback-Leibler Divergence. J Pharm Sci. 2017 05; 106(5):1239-1248.
    View in: PubMed
    Score: 0.525
  3. Gerhardt A, Nguyen BH, Lewus R, Carpenter JF, Randolph TW. Effect of the siliconization method on particle generation in a monoclonal antibody formulation in pre-filled syringes. J Pharm Sci. 2015 May; 104(5):1601-9.
    View in: PubMed
    Score: 0.459
  4. Alford JR, Kendrick BS, Carpenter JF, Randolph TW. High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics. J Pharm Sci. 2008 Aug; 97(8):3005-21.
    View in: PubMed
    Score: 0.291
  5. Webb SD, Koval CA, Randolph CM, Randolph TW. Electrochemical determination of dissolution rates of lyophilized pharmaceutical formulations. Anal Chem. 2001 Nov 01; 73(21):5296-301.
    View in: PubMed
    Score: 0.182
  6. Preston KB, Randolph TW. Stability of lyophilized and spray dried vaccine formulations. Adv Drug Deliv Rev. 2021 04; 171:50-61.
    View in: PubMed
    Score: 0.173
  7. Calderon CP, Daniels AL, Randolph TW. Deep Convolutional Neural Network Analysis of Flow Imaging Microscopy Data to Classify Subvisible Particles in Protein Formulations. J Pharm Sci. 2018 04; 107(4):999-1008.
    View in: PubMed
    Score: 0.139
  8. Gerhardt A, Mcumber AC, Nguyen BH, Lewus R, Schwartz DK, Carpenter JF, Randolph TW. Surfactant Effects on Particle Generation in Antibody Formulations in Pre-filled Syringes. J Pharm Sci. 2015 Dec; 104(12):4056-4064.
    View in: PubMed
    Score: 0.119
  9. Shomali M, Tanriverdi S, Freitag AJ, Engert J, Winter G, Siedler M, Kaymakcalan Z, Carpenter JF, Randolph TW. Dose levels in particulate-containing formulations impact anti-drug antibody responses to murine monoclonal antibody in mice. J Pharm Sci. 2015 May; 104(5):1610-21.
    View in: PubMed
    Score: 0.115
  10. Xu Y, Grobelny P, Von Allmen A, Knudson K, Pikal M, Carpenter JF, Randolph TW. Protein quantity on the air-solid interface determines degradation rates of human growth hormone in lyophilized samples. J Pharm Sci. 2014 May; 103(5):1356-66.
    View in: PubMed
    Score: 0.107
  11. Shomali M, Freitag A, Engert J, Siedler M, Kaymakcalan Z, Winter G, Carpenter JF, Randolph TW. Antibody responses in mice to particles formed from adsorption of a murine monoclonal antibody onto glass microparticles. J Pharm Sci. 2014 Jan; 103(1):78-89.
    View in: PubMed
    Score: 0.105
  12. Randolph TW, Randolph AD, Mebes M, Yeung S. Sub-micrometer-sized biodegradable particles of poly(L-lactic acid) via the gas antisolvent spray precipitation process. Biotechnol Prog. 1993 Jul-Aug; 9(4):429-35.
    View in: PubMed
    Score: 0.102
  13. Hassett KJ, Cousins MC, Rabia LA, Chadwick CM, O'Hara JM, Nandi P, Brey RN, Mantis NJ, Carpenter JF, Randolph TW. Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization. Eur J Pharm Biopharm. 2013 Oct; 85(2):279-86.
    View in: PubMed
    Score: 0.101
  14. Alford JR, Fowler AC, Wuttke DS, Kerwin BA, Latypov RF, Carpenter JF, Randolph TW. Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange. J Pharm Sci. 2011 Oct; 100(10):4215-24.
    View in: PubMed
    Score: 0.088
  15. Ludwig DB, Trotter JT, Gabrielson JP, Carpenter JF, Randolph TW. Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations. Anal Biochem. 2011 Mar 15; 410(2):191-9.
    View in: PubMed
    Score: 0.086
  16. Hoehne M, Samuel F, Dong A, Wurth C, Mahler HC, Carpenter JF, Randolph TW. Adsorption of monoclonal antibodies to glass microparticles. J Pharm Sci. 2011 Jan; 100(1):123-32.
    View in: PubMed
    Score: 0.083
  17. Salinas BA, Sathish HA, Bishop SM, Harn N, Carpenter JF, Randolph TW. Understanding and modulating opalescence and viscosity in a monoclonal antibody formulation. J Pharm Sci. 2010 Jan; 99(1):82-93.
    View in: PubMed
    Score: 0.080
  18. Gabrielson JP, Arthur KK, Kendrick BS, Randolph TW, Stoner MR. Common excipients impair detection of protein aggregates during sedimentation velocity analytical ultracentrifugation. J Pharm Sci. 2009 Jan; 98(1):50-62.
    View in: PubMed
    Score: 0.075
  19. Roy S, Henderson I, Nayar R, Randolph TW, Carpenter JF. Effect of pH on stability of recombinant botulinum serotype A vaccine in aqueous solution and during storage of freeze-dried formulations. J Pharm Sci. 2008 Dec; 97(12):5132-46.
    View in: PubMed
    Score: 0.074
  20. Clausi AL, Merkley SA, Carpenter JF, Randolph TW. Inhibition of aggregation of aluminum hydroxide adjuvant during freezing and drying. J Pharm Sci. 2008 Jun; 97(6):2049-61.
    View in: PubMed
    Score: 0.072
  21. Chi EY, Weickmann J, Carpenter JF, Manning MC, Randolph TW. Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation. J Pharm Sci. 2005 Feb; 94(2):256-74.
    View in: PubMed
    Score: 0.057
  22. Webb SD, Cleland JL, Carpenter JF, Randolph TW. Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma. J Pharm Sci. 2003 Apr; 92(4):715-29.
    View in: PubMed
    Score: 0.050
  23. Webb SD, Golledge SL, Cleland JL, Carpenter JF, Randolph TW. Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations. J Pharm Sci. 2002 Jun; 91(6):1474-87.
    View in: PubMed
    Score: 0.047
  24. Webb SD, Cleland JL, Carpenter JF, Randolph TW. A new mechanism for decreasing aggregation of recombinant human interferon-gamma by a surfactant: slowed dissolution of lyophilized formulations in a solution containing 0.03% polysorbate 20. J Pharm Sci. 2002 Feb; 91(2):543-58.
    View in: PubMed
    Score: 0.046
  25. Randolph TW, Jones LS. Surfactant-protein interactions. Pharm Biotechnol. 2002; 13:159-75.
    View in: PubMed
    Score: 0.046
  26. Mehta SB, Lewus R, Bee JS, Randolph TW, Carpenter JF. Gelation of a monoclonal antibody at the silicone oil-water interface and subsequent rupture of the interfacial gel results in aggregation and particle formation. J Pharm Sci. 2015 Apr; 104(4):1282-90.
    View in: PubMed
    Score: 0.029
  27. Basu P, Blake-Haskins AW, O'Berry KB, Randolph TW, Carpenter JF. Albinterferon a2b adsorption to silicone oil-water interfaces: effects on protein conformation, aggregation, and subvisible particle formation. J Pharm Sci. 2014 Feb; 103(2):427-36.
    View in: PubMed
    Score: 0.026
  28. Qi W, Zeng Y, Orgel S, Francon A, Kim JH, Randolph TW, Carpenter JF, Middaugh CR. Preformulation study of highly purified inactivated polio vaccine, serotype 3. J Pharm Sci. 2014 Jan; 103(1):140-51.
    View in: PubMed
    Score: 0.026
  29. Christie M, Torres RM, Kedl RM, Randolph TW, Carpenter JF. Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration. J Pharm Sci. 2014 Jan; 103(1):128-39.
    View in: PubMed
    Score: 0.026
  30. Izutsu K, Yomota C, Okuda H, Kawanishi T, Randolph TW, Carpenter JF. Impact of heat treatment on miscibility of proteins and disaccharides in frozen solutions. Eur J Pharm Biopharm. 2013 Oct; 85(2):177-83.
    View in: PubMed
    Score: 0.025
  31. Bee JS, Randolph TW, Carpenter JF, Bishop SM, Dimitrova MN. Effects of surfaces and leachables on the stability of biopharmaceuticals. J Pharm Sci. 2011 Oct; 100(10):4158-70.
    View in: PubMed
    Score: 0.022
  32. Serno T, Carpenter JF, Randolph TW, Winter G. Inhibition of agitation-induced aggregation of an IgG-antibody by hydroxypropyl-beta-cyclodextrin. J Pharm Sci. 2010 Mar; 99(3):1193-206.
    View in: PubMed
    Score: 0.020
  33. Stoner MR, Fischer N, Nixon L, Buckel S, Benke M, Austin F, Randolph TW, Kendrick BS. Protein-solute interactions affect the outcome of ultrafiltration/diafiltration operations. J Pharm Sci. 2004 Sep; 93(9):2332-42.
    View in: PubMed
    Score: 0.014
  34. Zhou H, Lengsfeld C, Claffey DJ, Ruth JA, Hybertson B, Randolph TW, Ng KY, Manning MC. Hydrophobic ion pairing of isoniazid using a prodrug approach. J Pharm Sci. 2002 Jun; 91(6):1502-11.
    View in: PubMed
    Score: 0.012
  35. Meyer JD, Falk RF, Kelly RM, Shively JE, Withrow SJ, Dernell WS, Kroll DJ, Randolph TW, Manning MC. Preparation and in vitro characterization of gentamycin-impregnated biodegradable beads suitable for treatment of osteomyelitis. J Pharm Sci. 1998 Sep; 87(9):1149-54.
    View in: PubMed
    Score: 0.009
  36. Bam NB, Randolph TW, Cleland JL. Stability of protein formulations: investigation of surfactant effects by a novel EPR spectroscopic technique. Pharm Res. 1995 Jan; 12(1):2-11.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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