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Connection

Theodore Randolph to Particle Size

This is a "connection" page, showing publications Theodore Randolph has written about Particle Size.

 
Connection Strength
  
 
 
4.050
  
  1. Maddux NR, Daniels AL, Randolph TW. Microflow Imaging Analyses Reflect Mechanisms of Aggregate Formation: Comparing Protein Particle Data Sets Using the Kullback-Leibler Divergence. J Pharm Sci. 2017 05; 106(5):1239-1248.
    View in: PubMed
    Score: 0.514
  2. Snell JR, Zhou C, Carpenter JF, Randolph TW. Particle Formation and Aggregation of a Therapeutic Protein in Nanobubble Suspensions. J Pharm Sci. 2016 10; 105(10):3057-3063.
    View in: PubMed
    Score: 0.496
  3. Gerhardt A, Nguyen BH, Lewus R, Carpenter JF, Randolph TW. Effect of the siliconization method on particle generation in a monoclonal antibody formulation in pre-filled syringes. J Pharm Sci. 2015 May; 104(5):1601-9.
    View in: PubMed
    Score: 0.450
  4. Thite NG, Ghazvini S, Wallace N, Feldman N, Calderon CP, Randolph TW. Machine Learning Analysis Provides Insight into Mechanisms of Protein Particle Formation Inside Containers During Mechanical Agitation. J Pharm Sci. 2022 10; 111(10):2730-2744.
    View in: PubMed
    Score: 0.187
  5. Wu H, Randolph TW. Aggregation and Particle Formation During Pumping of an Antibody Formulation Are Controlled by Electrostatic Interactions Between Pump Surfaces and Protein Molecules. J Pharm Sci. 2020 04; 109(4):1473-1482.
    View in: PubMed
    Score: 0.158
  6. Chisholm CF, Behnke W, Pokhilchuk Y, Frazer-Abel AA, Randolph TW. Subvisible Particles in IVIg Formulations Activate Complement in Human Serum. J Pharm Sci. 2020 01; 109(1):558-565.
    View in: PubMed
    Score: 0.155
  7. Snell JR, Monticello CR, Her C, Ross EL, Frazer-Abel AA, Carpenter JF, Randolph TW. DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum. J Pharm Sci. 2020 01; 109(1):429-442.
    View in: PubMed
    Score: 0.152
  8. Snell JR, Kumar NSK, Suryanarayanan R, Randolph TW. Nanobubbles in Reconstituted Lyophilized Formulations: Interaction With Proteins and Mechanism of Formation. J Pharm Sci. 2020 01; 109(1):284-292.
    View in: PubMed
    Score: 0.150
  9. Wu H, Randolph TW. Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations. J Pharm Sci. 2019 03; 108(3):1110-1116.
    View in: PubMed
    Score: 0.145
  10. Daniels AL, Randolph TW. Flow Microscopy Imaging Is Sensitive to Characteristics of Subvisible Particles in Peginesatide Formulations Associated With Severe Adverse Reactions. J Pharm Sci. 2018 05; 107(5):1313-1321.
    View in: PubMed
    Score: 0.138
  11. Chisholm CF, Baker AE, Soucie KR, Torres RM, Carpenter JF, Randolph TW. Silicone Oil Microdroplets Can Induce Antibody Responses Against Recombinant Murine Growth Hormone in Mice. J Pharm Sci. 2016 05; 105(5):1623-1632.
    View in: PubMed
    Score: 0.121
  12. Randolph TW, Schiltz E, Sederstrom D, Steinmann D, Mozziconacci O, Sch?neich C, Freund E, Ricci MS, Carpenter JF, Lengsfeld CS. Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation. J Pharm Sci. 2015 Feb; 104(2):602-11.
    View in: PubMed
    Score: 0.110
  13. Hassett KJ, Cousins MC, Rabia LA, Chadwick CM, O'Hara JM, Nandi P, Brey RN, Mantis NJ, Carpenter JF, Randolph TW. Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization. Eur J Pharm Biopharm. 2013 Oct; 85(2):279-86.
    View in: PubMed
    Score: 0.099
  14. Fradkin AH, Carpenter JF, Randolph TW. Glass particles as an adjuvant: a model for adverse immunogenicity of therapeutic proteins. J Pharm Sci. 2011 Nov; 100(11):4953-64.
    View in: PubMed
    Score: 0.087
  15. Ludwig DB, Trotter JT, Gabrielson JP, Carpenter JF, Randolph TW. Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations. Anal Biochem. 2011 Mar 15; 410(2):191-9.
    View in: PubMed
    Score: 0.084
  16. Hoehne M, Samuel F, Dong A, Wurth C, Mahler HC, Carpenter JF, Randolph TW. Adsorption of monoclonal antibodies to glass microparticles. J Pharm Sci. 2011 Jan; 100(1):123-32.
    View in: PubMed
    Score: 0.081
  17. Bee JS, Chiu D, Sawicki S, Stevenson JL, Chatterjee K, Freund E, Carpenter JF, Randolph TW. Monoclonal antibody interactions with micro- and nanoparticles: adsorption, aggregation, and accelerated stress studies. J Pharm Sci. 2009 Sep; 98(9):3218-38.
    View in: PubMed
    Score: 0.077
  18. Fradkin AH, Carpenter JF, Randolph TW. Immunogenicity of aggregates of recombinant human growth hormone in mouse models. J Pharm Sci. 2009 Sep; 98(9):3247-64.
    View in: PubMed
    Score: 0.077
  19. Clausi AL, Morin A, Carpenter JF, Randolph TW. Influence of protein conformation and adjuvant aggregation on the effectiveness of aluminum hydroxide adjuvant in a model alkaline phosphatase vaccine. J Pharm Sci. 2009 Jan; 98(1):114-21.
    View in: PubMed
    Score: 0.073
  20. Clausi A, Cummiskey J, Merkley S, Carpenter JF, Braun LJ, Randolph TW. Influence of particle size and antigen binding on effectiveness of aluminum salt adjuvants in a model lysozyme vaccine. J Pharm Sci. 2008 Dec; 97(12):5252-62.
    View in: PubMed
    Score: 0.073
  21. Clausi AL, Merkley SA, Carpenter JF, Randolph TW. Inhibition of aggregation of aluminum hydroxide adjuvant during freezing and drying. J Pharm Sci. 2008 Jun; 97(6):2049-61.
    View in: PubMed
    Score: 0.070
  22. Jarmer DJ, Lengsfeld CS, Anseth KS, Randolph TW. Supercritical fluid crystallization of griseofulvin: crystal habit modification with a selective growth inhibitor. J Pharm Sci. 2005 Dec; 94(12):2688-702.
    View in: PubMed
    Score: 0.059
  23. Jarmer DJ, Lengsfeld CS, Randolph TW. Nucleation and growth rates of poly(L-lactic acid) microparticles during precipitation with a compressed-fluid antisolvent. Langmuir. 2004 Aug 17; 20(17):7254-64.
    View in: PubMed
    Score: 0.054
  24. Benkstein KD, Balakrishnan G, Bhirde A, Chalus P, Das TK, Do N, Duewer DL, Filonov N, Cheong FC, Garidel P, Gill NS, Grabarek AD, Grier DG, Hadley J, Hollingsworth AD, Howard WW, Jarzebski M, Jiskoot W, Kar SR, Kestens V, Khasa H, Kim YJ, Koulov A, Matter A, Philips LA, Probst C, Ramaye Y, Randolph TW, Ripple DC, Romeijn S, Saggu M, Schleinzer F, Snell JR, Tatarkiewicz JK, Wright HA, Yang DT. An Interlaboratory Comparison on the Characterization of a Sub-micrometer Polydisperse Particle Dispersion. J Pharm Sci. 2022 03; 111(3):699-709.
    View in: PubMed
    Score: 0.045
  25. Her C, Tanenbaum LM, Bandi S, Randolph TW, Thirumangalathu R, Mallela KMG, Carpenter JF, Elias Y. Effects of Tubing Type, Operating Parameters, and Surfactants on Particle Formation During Peristaltic Filling Pump Processing of a mAb Formulation. J Pharm Sci. 2020 04; 109(4):1439-1448.
    View in: PubMed
    Score: 0.039
  26. Falk RF, Randolph TW. Process variable implications for residual solvent removal and polymer morphology in the formation of gentamycin-loaded poly (L-lactide) microparticles. Pharm Res. 1998 Aug; 15(8):1233-7.
    View in: PubMed
    Score: 0.036
  27. Pardeshi NN, Zhou C, Randolph TW, Carpenter JF. Protein Nanoparticles Promote Microparticle Formation in Intravenous Immunoglobulin Solutions During Freeze-Thawing and Agitation Stresses. J Pharm Sci. 2018 07; 107(7):1852-1857.
    View in: PubMed
    Score: 0.035
  28. Zhou C, Qi W, Lewis EN, Randolph TW, Carpenter JF. Reduced Subvisible Particle Formation in Lyophilized Intravenous Immunoglobulin Formulations Containing Polysorbate 20. J Pharm Sci. 2016 08; 105(8):2302-9.
    View in: PubMed
    Score: 0.031
  29. Zhou C, Cleland D, Snell J, Qi W, Randolph TW, Carpenter JF. Formation of Stable Nanobubbles on Reconstituting Lyophilized Formulations Containing Trehalose. J Pharm Sci. 2016 07; 105(7):2249-53.
    View in: PubMed
    Score: 0.031
  30. Barnard JG, Kahn D, Cetlin D, Randolph TW, Carpenter JF. Investigations into the fouling mechanism of parvovirus filters during filtration of freeze-thawed mAb drug substance solutions. J Pharm Sci. 2014 Mar; 103(3):890-9.
    View in: PubMed
    Score: 0.026
  31. Basu P, Blake-Haskins AW, O'Berry KB, Randolph TW, Carpenter JF. Albinterferon a2b adsorption to silicone oil-water interfaces: effects on protein conformation, aggregation, and subvisible particle formation. J Pharm Sci. 2014 Feb; 103(2):427-36.
    View in: PubMed
    Score: 0.026
  32. Christie M, Torres RM, Kedl RM, Randolph TW, Carpenter JF. Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration. J Pharm Sci. 2014 Jan; 103(1):128-39.
    View in: PubMed
    Score: 0.026
  33. Randolph TW, Randolph AD, Mebes M, Yeung S. Sub-micrometer-sized biodegradable particles of poly(L-lactic acid) via the gas antisolvent spray precipitation process. Biotechnol Prog. 1993 Jul-Aug; 9(4):429-35.
    View in: PubMed
    Score: 0.025
  34. Basu P, Krishnan S, Thirumangalathu R, Randolph TW, Carpenter JF. IgG1 aggregation and particle formation induced by silicone-water interfaces on siliconized borosilicate glass beads: a model for siliconized primary containers. J Pharm Sci. 2013 Mar; 102(3):852-65.
    View in: PubMed
    Score: 0.024
  35. Liu L, Randolph TW, Carpenter JF. Particles shed from syringe filters and their effects on agitation-induced protein aggregation. J Pharm Sci. 2012 Aug; 101(8):2952-9.
    View in: PubMed
    Score: 0.023
  36. Barnard JG, Singh S, Randolph TW, Carpenter JF. Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway. J Pharm Sci. 2011 Feb; 100(2):492-503.
    View in: PubMed
    Score: 0.021
  37. Carpenter JF, Randolph TW, Jiskoot W, Crommelin DJ, Middaugh CR, Winter G, Fan YX, Kirshner S, Verthelyi D, Kozlowski S, Clouse KA, Swann PG, Rosenberg A, Cherney B. Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality. J Pharm Sci. 2009 Apr; 98(4):1201-5.
    View in: PubMed
    Score: 0.019
  38. Tyagi AK, Randolph TW, Dong A, Maloney KM, Hitscherich C, Carpenter JF. IgG particle formation during filling pump operation: a case study of heterogeneous nucleation on stainless steel nanoparticles. J Pharm Sci. 2009 Jan; 98(1):94-104.
    View in: PubMed
    Score: 0.018
  39. Patel MM, Zeles MG, Manning MC, Randolph TW, Anchordoquy TJ. Degradation kinetics of high molecular weight poly(L-lactide) microspheres and release mechanism of lipid:DNA complexes. J Pharm Sci. 2004 Oct; 93(10):2573-84.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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