Connection
Theodore Randolph to Humans
This is a "connection" page, showing publications Theodore Randolph has written about Humans.
|
|
Connection Strength |
|
 |
|
 |
|
0.543 |
|
|
|
-
Thite NG, Tuberty-Vaughan E, Wilcox P, Wallace N, Calderon CP, Randolph TW. Stain-Free Approach to Determine and Monitor Cell Heath Using Supervised and Unsupervised Image-Based Deep Learning. J Pharm Sci. 2024 Aug; 113(8):2114-2127.
Score: 0.023
-
Coleman HJ, Schwartz DK, Kaar JL, Garcea RL, Randolph TW. Stabilization of an Infectious Enveloped Virus by Spray-Drying and Lyophilization. J Pharm Sci. 2024 Aug; 113(8):2072-2080.
Score: 0.023
-
Witeof AE, Meinerz NM, Walker KD, Funke HH, Garcea RL, Randolph TW. A Single Dose, Thermostable, Trivalent Human Papillomavirus Vaccine Formulated Using Atomic Layer Deposition. J Pharm Sci. 2023 08; 112(8):2223-2229.
Score: 0.021
-
Dong M, Meinerz NM, Walker KD, Garcea RL, Randolph TW. Thermostability of a trivalent, capsomere-based vaccine for human papillomavirus infection. Eur J Pharm Biopharm. 2021 Nov; 168:131-138.
Score: 0.019
-
Wu H, Movafaghi S, Francino Urd?niz IM, Rowe TM, Goodwin A, Randolph TW. Insulin Fibril Formation Caused by Mechanical Shock and Cavitation. J Phys Chem B. 2021 07 29; 125(29):8021-8027.
Score: 0.019
-
Chisholm CF, Behnke W, Pokhilchuk Y, Frazer-Abel AA, Randolph TW. Subvisible Particles in IVIg Formulations Activate Complement in Human Serum. J Pharm Sci. 2020 01; 109(1):558-565.
Score: 0.017
-
Snell JR, Monticello CR, Her C, Ross EL, Frazer-Abel AA, Carpenter JF, Randolph TW. DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum. J Pharm Sci. 2020 01; 109(1):429-442.
Score: 0.016
-
Snell JR, Kumar NSK, Suryanarayanan R, Randolph TW. Nanobubbles in Reconstituted Lyophilized Formulations: Interaction With Proteins and Mechanism of Formation. J Pharm Sci. 2020 01; 109(1):284-292.
Score: 0.016
-
Sorret LL, DeWinter MA, Schwartz DK, Randolph TW. Protein-protein interactions controlling interfacial aggregation of rhIL-1ra are not described by simple colloid models. Protein Sci. 2018 07; 27(7):1191-1204.
Score: 0.015
-
Daniels AL, Randolph TW. Flow Microscopy Imaging Is Sensitive to Characteristics of Subvisible Particles in Peginesatide Formulations Associated With Severe Adverse Reactions. J Pharm Sci. 2018 05; 107(5):1313-1321.
Score: 0.015
-
Snell JR, Zhou C, Carpenter JF, Randolph TW. Particle Formation and Aggregation of a Therapeutic Protein in Nanobubble Suspensions. J Pharm Sci. 2016 10; 105(10):3057-3063.
Score: 0.013
-
Gerhardt A, Nguyen BH, Lewus R, Carpenter JF, Randolph TW. Effect of the siliconization method on particle generation in a monoclonal antibody formulation in pre-filled syringes. J Pharm Sci. 2015 May; 104(5):1601-9.
Score: 0.012
-
Randolph TW, Schiltz E, Sederstrom D, Steinmann D, Mozziconacci O, Sch?neich C, Freund E, Ricci MS, Carpenter JF, Lengsfeld CS. Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation. J Pharm Sci. 2015 Feb; 104(2):602-11.
Score: 0.012
-
Xu Y, Grobelny P, Von Allmen A, Knudson K, Pikal M, Carpenter JF, Randolph TW. Protein quantity on the air-solid interface determines degradation rates of human growth hormone in lyophilized samples. J Pharm Sci. 2014 May; 103(5):1356-66.
Score: 0.011
-
Gerhardt A, Bonam K, Bee JS, Carpenter JF, Randolph TW. Ionic strength affects tertiary structure and aggregation propensity of a monoclonal antibody adsorbed to silicone oil-water interfaces. J Pharm Sci. 2013 Feb; 102(2):429-40.
Score: 0.010
-
Britt KA, Schwartz DK, Wurth C, Mahler HC, Carpenter JF, Randolph TW. Excipient effects on humanized monoclonal antibody interactions with silicone oil emulsions. J Pharm Sci. 2012 Dec; 101(12):4419-32.
Score: 0.010
-
Cordes AA, Carpenter JF, Randolph TW. Selective domain stabilization as a strategy to reduce human serum albumin-human granulocyte colony stimulating factor aggregation rate. J Pharm Sci. 2012 Jun; 101(6):2009-16.
Score: 0.010
-
Cordes AA, Platt CW, Carpenter JF, Randolph TW. Selective domain stabilization as a strategy to reduce fusion protein aggregation. J Pharm Sci. 2012 Apr; 101(4):1400-9.
Score: 0.010
-
Randolph TW. The two faces of His-tag: immune response versus ease of protein purification. Biotechnol J. 2012 Jan; 7(1):18-9.
Score: 0.010
-
Alford JR, Fowler AC, Wuttke DS, Kerwin BA, Latypov RF, Carpenter JF, Randolph TW. Effect of benzyl alcohol on recombinant human interleukin-1 receptor antagonist structure and hydrogen-deuterium exchange. J Pharm Sci. 2011 Oct; 100(10):4215-24.
Score: 0.009
-
Ludwig DB, Webb JN, Fern?ndez C, Carpenter JF, Randolph TW. Quaternary conformational stability: the effect of reversible self-association on the fibrillation of two insulin analogs. Biotechnol Bioeng. 2011 Oct; 108(10):2359-70.
Score: 0.009
-
Crisman RL, Randolph TW. Crystallization of recombinant human growth hormone at elevated pressures: pressure effects on PEG-induced volume exclusion interactions. Biotechnol Bioeng. 2010 Nov 01; 107(4):663-72.
Score: 0.009
-
Salinas BA, Sathish HA, Shah AU, Carpenter JF, Randolph TW. Buffer-dependent fragmentation of a humanized full-length monoclonal antibody. J Pharm Sci. 2010 Jul; 99(7):2962-74.
Score: 0.009
-
Bee JS, Davis M, Freund E, Carpenter JF, Randolph TW. Aggregation of a monoclonal antibody induced by adsorption to stainless steel. Biotechnol Bioeng. 2010 Jan 01; 105(1):121-9.
Score: 0.009
-
Fast JL, Cordes AA, Carpenter JF, Randolph TW. Physical instability of a therapeutic Fc fusion protein: domain contributions to conformational and colloidal stability. Biochemistry. 2009 Dec 15; 48(49):11724-36.
Score: 0.009
-
Bee JS, Nelson SA, Freund E, Carpenter JF, Randolph TW. Precipitation of a monoclonal antibody by soluble tungsten. J Pharm Sci. 2009 Sep; 98(9):3290-301.
Score: 0.008
-
Bee JS, Chiu D, Sawicki S, Stevenson JL, Chatterjee K, Freund E, Carpenter JF, Randolph TW. Monoclonal antibody interactions with micro- and nanoparticles: adsorption, aggregation, and accelerated stress studies. J Pharm Sci. 2009 Sep; 98(9):3218-38.
Score: 0.008
-
Fradkin AH, Carpenter JF, Randolph TW. Immunogenicity of aggregates of recombinant human growth hormone in mouse models. J Pharm Sci. 2009 Sep; 98(9):3247-64.
Score: 0.008
-
Alford JR, Kwok SC, Roberts JN, Wuttke DS, Kendrick BS, Carpenter JF, Randolph TW. High concentration formulations of recombinant human interleukin-1 receptor antagonist: I. Physical characterization. J Pharm Sci. 2008 Aug; 97(8):3035-50.
Score: 0.008
-
Alford JR, Kendrick BS, Carpenter JF, Randolph TW. Measurement of the second osmotic virial coefficient for protein solutions exhibiting monomer-dimer equilibrium. Anal Biochem. 2008 Jun 15; 377(2):128-33.
Score: 0.008
-
Seefeldt MB, Crouch C, Kendrick B, Randolph TW. Specific volume and adiabatic compressibility measurements of native and aggregated recombinant human interleukin-1 receptor antagonist: density differences enable pressure-modulated refolding. Biotechnol Bioeng. 2007 Oct 01; 98(2):476-85.
Score: 0.007
-
Gabrielson JP, Brader ML, Pekar AH, Mathis KB, Winter G, Carpenter JF, Randolph TW. Quantitation of aggregate levels in a recombinant humanized monoclonal antibody formulation by size-exclusion chromatography, asymmetrical flow field flow fractionation, and sedimentation velocity. J Pharm Sci. 2007 Feb; 96(2):268-79.
Score: 0.007
-
Seefeldt MB, Kim YS, Tolley KP, Seely J, Carpenter JF, Randolph TW. High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: thermodynamics, kinetics, and application to accelerated formulation studies. Protein Sci. 2005 Sep; 14(9):2258-66.
Score: 0.006
-
Wang Y, Hanford A, Boroumand M, Kalonia C, Leissa J, Shah M, Pham T, Randolph T, Prajapati I. Assessing subvisible particle risks in monoclonal antibodies: insights from quartz crystal microbalance with dissipation, machine learning, and in silico analysis. MAbs. 2025 Dec; 17(1):2501629.
Score: 0.006
-
Chi EY, Weickmann J, Carpenter JF, Manning MC, Randolph TW. Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation. J Pharm Sci. 2005 Feb; 94(2):256-74.
Score: 0.006
-
Seefeldt MB, Ouyang J, Froland WA, Carpenter JF, Randolph TW. High-pressure refolding of bikunin: efficacy and thermodynamics. Protein Sci. 2004 Oct; 13(10):2639-50.
Score: 0.006
-
Chi EY, Krishnan S, Kendrick BS, Chang BS, Carpenter JF, Randolph TW. Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony-stimulating factor. Protein Sci. 2003 May; 12(5):903-13.
Score: 0.005
-
Webb SD, Cleland JL, Carpenter JF, Randolph TW. Effects of annealing lyophilized and spray-lyophilized formulations of recombinant human interferon-gamma. J Pharm Sci. 2003 Apr; 92(4):715-29.
Score: 0.005
-
Webb SD, Golledge SL, Cleland JL, Carpenter JF, Randolph TW. Surface adsorption of recombinant human interferon-gamma in lyophilized and spray-lyophilized formulations. J Pharm Sci. 2002 Jun; 91(6):1474-87.
Score: 0.005
-
Randolph TW, Seefeldt M, Carpenter JF. High hydrostatic pressure as a tool to study protein aggregation and amyloidosis. Biochim Biophys Acta. 2002 Mar 25; 1595(1-2):224-34.
Score: 0.005
-
Webb SD, Cleland JL, Carpenter JF, Randolph TW. A new mechanism for decreasing aggregation of recombinant human interferon-gamma by a surfactant: slowed dissolution of lyophilized formulations in a solution containing 0.03% polysorbate 20. J Pharm Sci. 2002 Feb; 91(2):543-58.
Score: 0.005
-
St John RJ, Carpenter JF, Balny C, Randolph TW. High pressure refolding of recombinant human growth hormone from insoluble aggregates. Structural transformations, kinetic barriers, and energetics. J Biol Chem. 2001 Dec 14; 276(50):46856-63.
Score: 0.005
-
Webb JN, Webb SD, Cleland JL, Carpenter JF, Randolph TW. Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: high-pressure and cosolute studies on recombinant human IFN-gamma. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7259-64.
Score: 0.005
-
St John RJ, Carpenter JF, Randolph TW. High pressure fosters protein refolding from aggregates at high concentrations. Proc Natl Acad Sci U S A. 1999 Nov 09; 96(23):13029-33.
Score: 0.004
-
Jones LS, Cipolla D, Liu J, Shire SJ, Randolph TW. Investigation of protein-surfactant interactions by analytical ultracentrifugation and electron paramagnetic resonance: the use of recombinant human tissue factor as an example. Pharm Res. 1999 Jun; 16(6):808-12.
Score: 0.004
-
Heller MC, Carpenter JF, Randolph TW. Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation. Biotechnol Bioeng. 1999 Apr 20; 63(2):166-74.
Score: 0.004
-
Heller MC, Carpenter JF, Randolph TW. Conformational stability of lyophilized PEGylated proteins in a phase-separating system. J Pharm Sci. 1999 Jan; 88(1):58-64.
Score: 0.004
-
Carpenter JF, Kendrick BS, Chang BS, Manning MC, Randolph TW. Inhibition of stress-induced aggregation of protein therapeutics. Methods Enzymol. 1999; 309:236-55.
Score: 0.004
-
Bam NB, Cleland JL, Yang J, Manning MC, Carpenter JF, Kelley RF, Randolph TW. Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions. J Pharm Sci. 1998 Dec; 87(12):1554-9.
Score: 0.004
-
Kendrick BS, Carpenter JF, Cleland JL, Randolph TW. A transient expansion of the native state precedes aggregation of recombinant human interferon-gamma. Proc Natl Acad Sci U S A. 1998 Nov 24; 95(24):14142-6.
Score: 0.004
-
Qi W, Orgel S, Francon A, Randolph TW, Carpenter JF. Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations. J Pharm Sci. 2018 08; 107(8):2070-2078.
Score: 0.004
-
Nejadnik MR, Randolph TW, Volkin DB, Sch?neich C, Carpenter JF, Crommelin DJA, Jiskoot W. Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues. J Pharm Sci. 2018 08; 107(8):2013-2019.
Score: 0.004
-
Bam NB, Cleland JL, Randolph TW. Molten globule intermediate of recombinant human growth hormone: stabilization with surfactants. Biotechnol Prog. 1996 Nov-Dec; 12(6):801-9.
Score: 0.003
-
Jiskoot W, Kijanka G, Randolph TW, Carpenter JF, Koulov AV, Mahler HC, Joubert MK, Jawa V, Narhi LO. Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges. J Pharm Sci. 2016 05; 105(5):1567-1575.
Score: 0.003
-
Christie M, Peritt D, Torres RM, Randolph TW, Carpenter JF. The Role of Protein Excipient in Driving Antibody Responses to Erythropoietin. J Pharm Sci. 2015 Dec; 104(12):4041-4055.
Score: 0.003
-
Barnard JG, Kahn D, Cetlin D, Randolph TW, Carpenter JF. Investigations into the fouling mechanism of parvovirus filters during filtration of freeze-thawed mAb drug substance solutions. J Pharm Sci. 2014 Mar; 103(3):890-9.
Score: 0.003
-
Liu L, Qi W, Schwartz DK, Randolph TW, Carpenter JF. The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study. J Pharm Sci. 2013 Aug; 102(8):2460-70.
Score: 0.003
-
Chou DK, Krishnamurthy R, Manning MC, Randolph TW, Carpenter JF. Physical stability of albinterferon-a(2b) in aqueous solution: effects of conformational stability and colloidal stability on aggregation. J Pharm Sci. 2012 Aug; 101(8):2702-19.
Score: 0.003
-
Liu L, Randolph TW, Carpenter JF. Particles shed from syringe filters and their effects on agitation-induced protein aggregation. J Pharm Sci. 2012 Aug; 101(8):2952-9.
Score: 0.003
-
Jiskoot W, Randolph TW, Volkin DB, Middaugh CR, Sch?neich C, Winter G, Friess W, Crommelin DJ, Carpenter JF. Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. J Pharm Sci. 2012 Mar; 101(3):946-54.
Score: 0.002
-
Van Beers MM, Gilli F, Schellekens H, Randolph TW, Jiskoot W. Immunogenicity of recombinant human interferon beta interacting with particles of glass, metal, and polystyrene. J Pharm Sci. 2012 Jan; 101(1):187-99.
Score: 0.002
-
Bai S, Manning MC, Randolph TW, Carpenter JF. Aggregation of recombinant human botulinum protein antigen serotype C in varying solution conditions: implications of conformational stability for aggregation kinetics. J Pharm Sci. 2011 Mar; 100(3):836-48.
Score: 0.002
-
Thirumangalathu R, Krishnan S, Bondarenko P, Speed-Ricci M, Randolph TW, Carpenter JF, Brems DN. Oxidation of methionine residues in recombinant human interleukin-1 receptor antagonist: implications of conformational stability on protein oxidation kinetics. Biochemistry. 2007 May 29; 46(21):6213-24.
Score: 0.002
-
Thirumangalathu R, Krishnan S, Brems DN, Randolph TW, Carpenter JF. Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor. J Pharm Sci. 2006 Jul; 95(7):1480-97.
Score: 0.002
-
Lee SH, Carpenter JF, Chang BS, Randolph TW, Kim YS. Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure. Protein Sci. 2006 Feb; 15(2):304-13.
Score: 0.002
-
Chou DK, Krishnamurthy R, Randolph TW, Carpenter JF, Manning MC. Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation. J Pharm Sci. 2005 Jun; 94(6):1368-81.
Score: 0.002
-
Roy S, Jung R, Kerwin BA, Randolph TW, Carpenter JF. Effects of benzyl alcohol on aggregation of recombinant human interleukin-1-receptor antagonist in reconstituted lyophilized formulations. J Pharm Sci. 2005 Feb; 94(2):382-96.
Score: 0.002
-
Zhang Y, Roy S, Jones LS, Krishnan S, Kerwin BA, Chang BS, Manning MC, Randolph TW, Carpenter JF. Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution. J Pharm Sci. 2004 Dec; 93(12):3076-89.
Score: 0.002
-
Garzon-Rodriguez W, Koval RL, Chongprasert S, Krishnan S, Randolph TW, Warne NW, Carpenter JF. Optimizing storage stability of lyophilized recombinant human interleukin-11 with disaccharide/hydroxyethyl starch mixtures. J Pharm Sci. 2004 Mar; 93(3):684-96.
Score: 0.001
-
Krishnan S, Chi EY, Wood SJ, Kendrick BS, Li C, Garzon-Rodriguez W, Wypych J, Randolph TW, Narhi LO, Biere AL, Citron M, Carpenter JF. Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis. Biochemistry. 2003 Jan 28; 42(3):829-37.
Score: 0.001
-
Kim YS, Randolph TW, Manning MC, Stevens FJ, Carpenter JF. Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation. J Biol Chem. 2003 Mar 21; 278(12):10842-50.
Score: 0.001
-
Stay MS, Xu J, Randolph TW, Barocas VH. Computer simulation of convective and diffusive transport of controlled-release drugs in the vitreous humor. Pharm Res. 2003 Jan; 20(1):96-102.
Score: 0.001
-
Krishnan S, Chi EY, Webb JN, Chang BS, Shan D, Goldenberg M, Manning MC, Randolph TW, Carpenter JF. Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition. Biochemistry. 2002 May 21; 41(20):6422-31.
Score: 0.001
-
Kim YS, Randolph TW, Stevens FJ, Carpenter JF. Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies. J Biol Chem. 2002 Jul 26; 277(30):27240-6.
Score: 0.001
-
Kim YS, Cape SP, Chi E, Raffen R, Wilkins-Stevens P, Stevens FJ, Manning MC, Randolph TW, Solomon A, Carpenter JF. Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains. J Biol Chem. 2001 Jan 12; 276(2):1626-33.
Score: 0.001
-
Yang TH, Cleland JL, Lam X, Meyer JD, Jones LS, Randolph TW, Manning MC, Carpenter JF. Effect of zinc binding and precipitation on structures of recombinant human growth hormone and nerve growth factor. J Pharm Sci. 2000 Nov; 89(11):1480-5.
Score: 0.001
-
Allison SD, Manning MC, Randolph TW, Middleton K, Davis A, Carpenter JF. Optimization of storage stability of lyophilized actin using combinations of disaccharides and dextran. J Pharm Sci. 2000 Feb; 89(2):199-214.
Score: 0.001
-
Kim Y, Wall JS, Meyer J, Murphy C, Randolph TW, Manning MC, Solomon A, Carpenter JF. Thermodynamic modulation of light chain amyloid fibril formation. J Biol Chem. 2000 Jan 21; 275(3):1570-4.
Score: 0.001
-
Kreilgaard L, Frokjaer S, Flink JM, Randolph TW, Carpenter JF. Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid. Arch Biochem Biophys. 1998 Dec 01; 360(1):121-34.
Score: 0.001
-
Kreilgaard L, Jones LS, Randolph TW, Frokjaer S, Flink JM, Manning MC, Carpenter JF. Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII. J Pharm Sci. 1998 Dec; 87(12):1597-603.
Score: 0.001
-
Kendrick BS, Cleland JL, Lam X, Nguyen T, Randolph TW, Manning MC, Carpenter JF. Aggregation of recombinant human interferon gamma: kinetics and structural transitions. J Pharm Sci. 1998 Sep; 87(9):1069-76.
Score: 0.001
-
Kendrick BS, Chang BS, Arakawa T, Peterson B, Randolph TW, Manning MC, Carpenter JF. Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state. Proc Natl Acad Sci U S A. 1997 Oct 28; 94(22):11917-22.
Score: 0.001
|
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
|