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Connection

David Schwartz to Animals

This is a "connection" page, showing publications David Schwartz has written about Animals.

 
Connection Strength
 
 
 
1.842
 
  1. Dobrinskikh E, Hennessy CE, Kurche JS, Kim E, Estrella AM, Cardwell J, Yang IV, Schwartz DA. Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis. Am J Respir Cell Mol Biol. 2023 01; 68(1):62-74.
    View in: PubMed
    Score: 0.048
  2. Kurche JS, Stancil IT, Michalski JE, Yang IV, Schwartz DA. Dysregulated Cell-Cell Communication Characterizes Pulmonary Fibrosis. Cells. 2022 10 21; 11(20).
    View in: PubMed
    Score: 0.047
  3. Okamoto T, Dobrinskikh E, Hennessy CE, Liu N, Schwarz MI, Evans CM, Fontenot AP, Yang IV, Schwartz DA. Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced by Saccharopolyspora rectivirgula. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L329-L337.
    View in: PubMed
    Score: 0.046
  4. Stancil IT, Michalski JE, Hennessy CE, Hatakka KL, Yang IV, Kurche JS, Rincon M, Schwartz DA. Interleukin-6-dependent epithelial fluidization initiates fibrotic lung remodeling. Sci Transl Med. 2022 07 20; 14(654):eabo5254.
    View in: PubMed
    Score: 0.046
  5. Dobrinskikh E, Estrella AM, Hennessy CE, Hara N, Schwarz MI, Kurche JS, Yang IV, Schwartz DA. Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol. 2021 08 01; 321(2):L440-L450.
    View in: PubMed
    Score: 0.043
  6. Kurche JS, Dobrinskikh E, Hennessy CE, Huber J, Estrella A, Hancock LA, Schwarz MI, Okamoto T, Cool CD, Yang IV, Evans CM, Schwartz DA. Muc5b Enhances Murine Honeycomb-like Cyst Formation. Am J Respir Cell Mol Biol. 2019 10; 61(4):544-546.
    View in: PubMed
    Score: 0.038
  7. Albert RK, Smith B, Perlman CE, Schwartz DA. Is Progression of Pulmonary Fibrosis due to Ventilation-induced Lung Injury? Am J Respir Crit Care Med. 2019 07 15; 200(2):140-151.
    View in: PubMed
    Score: 0.038
  8. Albert RK, Schwartz DA. Revealing the Secrets of Idiopathic Pulmonary Fibrosis. N Engl J Med. 2019 01 03; 380(1):94-96.
    View in: PubMed
    Score: 0.036
  9. Hancock LA, Hennessy CE, Solomon GM, Dobrinskikh E, Estrella A, Hara N, Hill DB, Kissner WJ, Markovetz MR, Grove Villalon DE, Voss ME, Tearney GJ, Carroll KS, Shi Y, Schwarz MI, Thelin WR, Rowe SM, Yang IV, Evans CM, Schwartz DA. Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice. Nat Commun. 2018 12 18; 9(1):5363.
    View in: PubMed
    Score: 0.036
  10. Okamoto T, Mathai SK, Hennessy CE, Hancock LA, Walts AD, Stefanski AL, Brown KK, Lynch DA, Cosgrove GP, Groshong SD, Cool CD, Schwarz MI, Banda NK, Thurman JM, Yang IV, Holers VM, Schwartz DA. The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2018 07 01; 315(1):L1-L10.
    View in: PubMed
    Score: 0.034
  11. Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA. Methylene-tetrahydrofolate reductase contributes to allergic airway disease. PLoS One. 2018; 13(1):e0190916.
    View in: PubMed
    Score: 0.034
  12. Yang IV, Lozupone CA, Schwartz DA. The environment, epigenome, and asthma. J Allergy Clin Immunol. 2017 Jul; 140(1):14-23.
    View in: PubMed
    Score: 0.033
  13. Evans CM, Fingerlin TE, Schwarz MI, Lynch D, Kurche J, Warg L, Yang IV, Schwartz DA. Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways. Physiol Rev. 2016 10; 96(4):1567-91.
    View in: PubMed
    Score: 0.031
  14. Eyring KR, Pedersen BS, Yang IV, Schwartz DA. In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome. PLoS One. 2015; 10(12):e0144087.
    View in: PubMed
    Score: 0.029
  15. Yang IV, Schwartz DA. Epigenetics of idiopathic pulmonary fibrosis. Transl Res. 2015 Jan; 165(1):48-60.
    View in: PubMed
    Score: 0.026
  16. Jing J, Yang IV, Hui L, Patel JA, Evans CM, Prikeris R, Kobzik L, O'Connor BP, Schwartz DA. Role of macrophage receptor with collagenous structure in innate immune tolerance. J Immunol. 2013 Jun 15; 190(12):6360-7.
    View in: PubMed
    Score: 0.024
  17. Yang IV, Schwartz DA. Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol. 2012 Dec; 130(6):1243-55.
    View in: PubMed
    Score: 0.023
  18. Yang IV, Rutledge HR, Yang J, Warg LA, Sevilla SD, Schwartz DA. A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS. Mamm Genome. 2011 Oct; 22(9-10):518-29.
    View in: PubMed
    Score: 0.022
  19. Seibold MA, Schwartz DA. The lung: the natural boundary between nature and nurture. Annu Rev Physiol. 2011; 73:457-78.
    View in: PubMed
    Score: 0.021
  20. Yang IV, Alper S, Lackford B, Rutledge H, Warg LA, Burch LH, Schwartz DA. Novel regulators of the systemic response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):393-402.
    View in: PubMed
    Score: 0.021
  21. Schwartz DA. Epigenetics and environmental lung disease. Proc Am Thorac Soc. 2010 May; 7(2):123-5.
    View in: PubMed
    Score: 0.020
  22. Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA. The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem. 2010 Jan 15; 285(3):1822-8.
    View in: PubMed
    Score: 0.019
  23. Yang IV, Wade CM, Kang HM, Alper S, Rutledge H, Lackford B, Eskin E, Daly MJ, Schwartz DA. Identification of novel genes that mediate innate immunity using inbred mice. Genetics. 2009 Dec; 183(4):1535-44.
    View in: PubMed
    Score: 0.019
  24. Senthilselvan A, Dosman JA, Ch?nard L, Burch LH, Predicala BZ, Sorowski R, Schneberger D, Hurst T, Kirychuk S, Gerdts V, Cormier Y, Rennie DC, Schwartz DA. Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility. J Allergy Clin Immunol. 2009 May; 123(5):1034-40, 1040.e1-2.
    View in: PubMed
    Score: 0.018
  25. Brass DM, Wise AL, Schwartz DA. Host-environment interactions in exposure-related diffuse lung diseases. Semin Respir Crit Care Med. 2008 Dec; 29(6):603-9.
    View in: PubMed
    Score: 0.018
  26. Boon K, Tomfohr JK, Bailey NW, Garantziotis S, Li Z, Brass DM, Maruoka S, Hollingsworth JW, Schwartz DA. Evaluating genome-wide DNA methylation changes in mice by Methylation Specific Digital Karyotyping. BMC Genomics. 2008 Dec 11; 9:598.
    View in: PubMed
    Score: 0.018
  27. Hollingsworth JW, Maruoka S, Boon K, Garantziotis S, Li Z, Tomfohr J, Bailey N, Potts EN, Whitehead G, Brass DM, Schwartz DA. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2008 Oct; 118(10):3462-9.
    View in: PubMed
    Score: 0.018
  28. Garantziotis S, Zudaire E, Trempus CS, Hollingsworth JW, Jiang D, Lancaster LH, Richardson E, Zhuo L, Cuttitta F, Brown KK, Noble PW, Kimata K, Schwartz DA. Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury. Am J Respir Crit Care Med. 2008 Nov 01; 178(9):939-47.
    View in: PubMed
    Score: 0.018
  29. Marraccini P, Brass DM, Hollingsworth JW, Maruoka S, Garantziotis S, Schwartz DA. Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice. Clin Exp Allergy. 2008 Sep; 38(9):1526-35.
    View in: PubMed
    Score: 0.017
  30. Zaas AK, Liao G, Chien JW, Weinberg C, Shore D, Giles SS, Marr KA, Usuka J, Burch LH, Perera L, Perfect JR, Peltz G, Schwartz DA. Plasminogen alleles influence susceptibility to invasive aspergillosis. PLoS Genet. 2008 Jun 20; 4(6):e1000101.
    View in: PubMed
    Score: 0.017
  31. Brass DM, Yang IV, Kennedy MP, Whitehead GS, Rutledge H, Burch LH, Schwartz DA. Fibroproliferation in LPS-induced airway remodeling and bleomycin-induced fibrosis share common patterns of gene expression. Immunogenetics. 2008 Jul; 60(7):353-69.
    View in: PubMed
    Score: 0.017
  32. Brass DM, Hollingsworth JW, Cinque M, Li Z, Potts E, Toloza E, Foster WM, Schwartz DA. Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis. Am J Respir Cell Mol Biol. 2008 Nov; 39(5):584-90.
    View in: PubMed
    Score: 0.017
  33. Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):7016-21.
    View in: PubMed
    Score: 0.017
  34. Garantziotis S, Palmer SM, Snyder LD, Ganous T, Chen BJ, Wang T, Cook DN, Schwartz DA. Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. Transplantation. 2007 Oct 27; 84(8):1012-9.
    View in: PubMed
    Score: 0.017
  35. Hollingsworth JW, Maruoka S, Li Z, Potts EN, Brass DM, Garantziotis S, Fong A, Foster WM, Schwartz DA. Ambient ozone primes pulmonary innate immunity in mice. J Immunol. 2007 Oct 01; 179(7):4367-75.
    View in: PubMed
    Score: 0.017
  36. Garantziotis S, Hollingsworth JW, Ghanayem RB, Timberlake S, Zhuo L, Kimata K, Schwartz DA. Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury. J Immunol. 2007 Sep 15; 179(6):4187-92.
    View in: PubMed
    Score: 0.017
  37. Hollingsworth JW, Whitehead G, Berman KG, Tekippe EM, Gilmour MI, Larkin JE, Quackenbush J, Schwartz DA. Genetic basis of murine antibacterial defense to streptococcal lung infection. Immunogenetics. 2007 Sep; 59(9):713-24.
    View in: PubMed
    Score: 0.016
  38. Alper S, McBride SJ, Lackford B, Freedman JH, Schwartz DA. Specificity and complexity of the Caenorhabditis elegans innate immune response. Mol Cell Biol. 2007 Aug; 27(15):5544-53.
    View in: PubMed
    Score: 0.016
  39. Brass DM, Hollingsworth JW, Fessler MB, Savov JD, Maxwell AB, Whitehead GS, Burch LH, Schwartz DA. The IL-1 type 1 receptor is required for the development of LPS-induced airways disease. J Allergy Clin Immunol. 2007 Jul; 120(1):121-7.
    View in: PubMed
    Score: 0.016
  40. Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):248-53.
    View in: PubMed
    Score: 0.016
  41. Brass DM, Hollingsworth JW, McElvania-Tekippe E, Garantziotis S, Hossain I, Schwartz DA. CD14 is an essential mediator of LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L77-83.
    View in: PubMed
    Score: 0.016
  42. Brass DM, Tomfohr J, Yang IV, Schwartz DA. Using mouse genomics to understand idiopathic interstitial fibrosis. Proc Am Thorac Soc. 2007 Jan; 4(1):92-100.
    View in: PubMed
    Score: 0.016
  43. Whitehead GS, Burch LH, Berman KG, Piantadosi CA, Schwartz DA. Genetic basis of murine responses to hyperoxia-induced lung injury. Immunogenetics. 2006 Oct; 58(10):793-804.
    View in: PubMed
    Score: 0.015
  44. Yang IV, Burch LH, Steele MP, Savov JD, Hollingsworth JW, McElvania-Tekippe E, Berman KG, Speer MC, Sporn TA, Brown KK, Schwarz MI, Schwartz DA. Gene expression profiling of familial and sporadic interstitial pneumonia. Am J Respir Crit Care Med. 2007 Jan 01; 175(1):45-54.
    View in: PubMed
    Score: 0.015
  45. Garantziotis S, Brass DM, Savov J, Hollingsworth JW, McElvania-TeKippe E, Berman K, Walker JK, Schwartz DA. Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. Am J Respir Cell Mol Biol. 2006 Dec; 35(6):662-7.
    View in: PubMed
    Score: 0.015
  46. Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA. The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L677-82.
    View in: PubMed
    Score: 0.015
  47. Walker JK, Ahumada A, Frank B, Gaspard R, Berman K, Quackenbush J, Schwartz DA. Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2006 Jun; 34(6):711-8.
    View in: PubMed
    Score: 0.015
  48. Cook DN, Whitehead GS, Burch LH, Berman KG, Kapadia Z, Wohlford-Lenane C, Schwartz DA. Spontaneous mutations in recombinant inbred mice: mutant toll-like receptor 4 (Tlr4) in BXD29 mice. Genetics. 2006 Mar; 172(3):1751-5.
    View in: PubMed
    Score: 0.015
  49. Schwartz DA, Cook DN. Polymorphisms of the Toll-like receptors and human disease. Clin Infect Dis. 2005 Nov 15; 41 Suppl 7:S403-7.
    View in: PubMed
    Score: 0.015
  50. Savov JD, Brass DM, Lawson BL, McElvania-Tekippe E, Walker JK, Schwartz DA. Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol. 2005 Aug; 289(2):L329-37.
    View in: PubMed
    Score: 0.014
  51. Singh J, Schwartz DA. Endotoxin and the lung: Insight into the host-environment interaction. J Allergy Clin Immunol. 2005 Feb; 115(2):330-3.
    View in: PubMed
    Score: 0.014
  52. Burch LH, Schwartz DA. Finding fibrosis genes: the lung. Methods Mol Med. 2005; 117:293-313.
    View in: PubMed
    Score: 0.014
  53. Hollingsworth JW, Chen BJ, Brass DM, Berman K, Gunn MD, Cook DN, Schwartz DA. The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation. Am J Respir Crit Care Med. 2005 Apr 15; 171(8):806-13.
    View in: PubMed
    Score: 0.014
  54. Cook DN, Pisetsky DS, Schwartz DA. Toll-like receptors in the pathogenesis of human disease. Nat Immunol. 2004 Oct; 5(10):975-9.
    View in: PubMed
    Score: 0.013
  55. Brass DM, Savov JD, Whitehead GS, Maxwell AB, Schwartz DA. LPS binding protein is important in the airway response to inhaled endotoxin. J Allergy Clin Immunol. 2004 Sep; 114(3):586-92.
    View in: PubMed
    Score: 0.013
  56. Garantziotis S, Steele MP, Schwartz DA. Pulmonary fibrosis: thinking outside of the lung. J Clin Invest. 2004 Aug; 114(3):319-21.
    View in: PubMed
    Score: 0.013
  57. Cook DN, Wang S, Wang Y, Howles GP, Whitehead GS, Berman KG, Church TD, Frank BC, Gaspard RM, Yu Y, Quackenbush J, Schwartz DA. Genetic regulation of endotoxin-induced airway disease. Genomics. 2004 Jun; 83(6):961-9.
    View in: PubMed
    Score: 0.013
  58. Hollingsworth JW, Cook DN, Brass DM, Walker JK, Morgan DL, Foster WM, Schwartz DA. The role of Toll-like receptor 4 in environmental airway injury in mice. Am J Respir Crit Care Med. 2004 Jul 15; 170(2):126-32.
    View in: PubMed
    Score: 0.013
  59. Savov JD, Whitehead GS, Wang J, Liao G, Usuka J, Peltz G, Foster WM, Schwartz DA. Ozone-induced acute pulmonary injury in inbred mouse strains. Am J Respir Cell Mol Biol. 2004 Jul; 31(1):69-77.
    View in: PubMed
    Score: 0.013
  60. Cook DN, Hollingsworth JW, Schwartz DA. Toll-like receptors and the genetics of innate immunity. Curr Opin Allergy Clin Immunol. 2003 Dec; 3(6):523-9.
    View in: PubMed
    Score: 0.013
  61. Savov JD, Brass DM, Berman KG, McElvania E, Schwartz DA. Fibrinolysis in LPS-induced chronic airway disease. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L940-8.
    View in: PubMed
    Score: 0.012
  62. Brass DM, Savov JD, Gavett SH, Haykal-Coates N, Schwartz DA. Subchronic endotoxin inhalation causes persistent airway disease. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L755-61.
    View in: PubMed
    Score: 0.012
  63. Whitehead GS, Walker JK, Berman KG, Foster WM, Schwartz DA. Allergen-induced airway disease is mouse strain dependent. Am J Physiol Lung Cell Mol Physiol. 2003 Jul; 285(1):L32-42.
    View in: PubMed
    Score: 0.012
  64. Cook DN, Wang S, Howles GP, Speer M, Churchhill G, Quackenbush J, Schwartz DA. The genetics of innate immunity in the lung. Chest. 2003 Mar; 123(3 Suppl):369S.
    View in: PubMed
    Score: 0.012
  65. Brass DM, Savov JD, Schwartz DA. Intercellular adhesion molecule-1 plays a pivotal role in endotoxin-induced airway disease. Chest. 2003 Mar; 123(3 Suppl):416S.
    View in: PubMed
    Score: 0.012
  66. Cooley JC, Javkhlan N, Wilson JA, Foster DG, Edelman BL, Ortiz LA, Schwartz DA, Riches DW, Redente EF. Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis. JCI Insight. 2023 02 08; 8(3).
    View in: PubMed
    Score: 0.012
  67. Wang D, Li W, Albasha N, Griffin L, Chang H, Amaya L, Ganguly S, Zeng L, Keum B, Gonz?lez-Navajas JM, Levin M, AkhavanAghdam Z, Snyder H, Schwartz D, Tao A, Boosherhri LM, Hoffman HM, Rose M, Estrada MV, Varki N, Herdman S, Corr M, Webster NJG, Raz E, Bertin S. Long-term exposure to house dust mites accelerates lung cancer development in mice. J Exp Clin Cancer Res. 2023 Jan 21; 42(1):26.
    View in: PubMed
    Score: 0.012
  68. Cook DN, Brass DM, Schwartz DA. A matrix for new ideas in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2002 Aug; 27(2):122-4.
    View in: PubMed
    Score: 0.012
  69. Schwartz DA. The genetics of innate immunity. Chest. 2002 Mar; 121(3 Suppl):62S-68S.
    View in: PubMed
    Score: 0.011
  70. Zeldin DC, Wohlford-Lenane C, Chulada P, Bradbury JA, Scarborough PE, Roggli V, Langenbach R, Schwartz DA. Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol. 2001 Oct; 25(4):457-65.
    View in: PubMed
    Score: 0.011
  71. Schwartz DA, Christ WJ, Kleeberger SR, Wohlford-Lenane CL. Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists. Am J Physiol Lung Cell Mol Physiol. 2001 Apr; 280(4):L771-8.
    View in: PubMed
    Score: 0.011
  72. Gao Z, Dosman JA, Rennie DC, Schwartz DA, Yang IV, Beach J, Senthilselvan A. Effects of tumor necrosis factor (TNF) gene polymorphisms on the association between smoking and lung function among workers in swine operations. J Toxicol Environ Health A. 2021 07 03; 84(13):536-552.
    View in: PubMed
    Score: 0.011
  73. George CL, Jin H, Wohlford-Lenane CL, O'Neill ME, Phipps JC, O'Shaughnessy P, Kline JN, Thorne PS, Schwartz DA. Endotoxin responsiveness and subchronic grain dust-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2001 Feb; 280(2):L203-13.
    View in: PubMed
    Score: 0.010
  74. Schwartz DA. Does inhalation of endotoxin cause asthma? Am J Respir Crit Care Med. 2001 Feb; 163(2):305-6.
    View in: PubMed
    Score: 0.010
  75. Moreland JG, Fuhrman RM, Wohlford-Lenane CL, Quinn TJ, Benda E, Pruessner JA, Schwartz DA. TNF-alpha and IL-1 beta are not essential to the inflammatory response in LPS-induced airway disease. Am J Physiol Lung Cell Mol Physiol. 2001 Jan; 280(1):L173-80.
    View in: PubMed
    Score: 0.010
  76. Lorenz E, Mira JP, Cornish KL, Arbour NC, Schwartz DA. A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect Immun. 2000 Nov; 68(11):6398-401.
    View in: PubMed
    Score: 0.010
  77. Quinn TJ, Taylor S, Wohlford-Lenane CL, Schwartz DA. IL-10 reduces grain dust-induced airway inflammation and airway hyperreactivity. J Appl Physiol (1985). 2000 Jan; 88(1):173-9.
    View in: PubMed
    Score: 0.010
  78. Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK. ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites. J Exp Med. 2019 12 02; 216(12):2714-2723.
    View in: PubMed
    Score: 0.010
  79. Schwartz DA, Wohlford-Lenane CL, Quinn TJ, Krieg AM. Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway. J Immunol. 1999 Jul 01; 163(1):224-31.
    View in: PubMed
    Score: 0.009
  80. Schwartz DA. Etiology and pathogenesis of airway disease in children and adults from rural communities. Environ Health Perspect. 1999 Jun; 107 Suppl 3:393-401.
    View in: PubMed
    Score: 0.009
  81. Wohlford-Lenane CL, Deetz DC, Schwartz DA. Cytokine gene expression after inhalation of corn dust. Am J Physiol. 1999 05; 276(5):L736-43.
    View in: PubMed
    Score: 0.009
  82. Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM, Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafr?n L, Chonmaitree T, Sale MM, Ahmed ZM. FUT2 Variants Confer Susceptibility to Familial Otitis Media. Am J Hum Genet. 2018 11 01; 103(5):679-690.
    View in: PubMed
    Score: 0.009
  83. Musunuru K, Bernstein D, Cole FS, Khokha MK, Lee FS, Lin S, McDonald TV, Moskowitz IP, Quertermous T, Sankaran VG, Schwartz DA, Silverman EK, Zhou X, Hasan AAK, Luo XJ. Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research. Circ Genom Precis Med. 2018 04; 11(4):e002178.
    View in: PubMed
    Score: 0.009
  84. Jagielo PJ, Quinn TJ, Qureshi N, Schwartz DA. Grain dust-induced lung inflammation is reduced by Rhodobacter sphaeroides diphosphoryl lipid A. Am J Physiol. 1998 01; 274(1):L26-31.
    View in: PubMed
    Score: 0.008
  85. Peiffer-Schneider S, Schutte BC, Murray JC, Frees KL, Williamson K, Leysens NJ, Schwartz DA. Exclusion of Ifa and Ifb as the Lps gene and mapping of three markers near the Lps locus. Mamm Genome. 1997 Oct; 8(10):785-6.
    View in: PubMed
    Score: 0.008
  86. Schwartz DA, Quinn TJ, Thorne PS, Sayeed S, Yi AK, Krieg AM. CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract. J Clin Invest. 1997 Jul 01; 100(1):68-73.
    View in: PubMed
    Score: 0.008
  87. Deetz DC, Jagielo PJ, Quinn TJ, Thorne PS, Bleuer SA, Schwartz DA. The kinetics of grain dust-induced inflammation of the lower respiratory tract. Am J Respir Crit Care Med. 1997 Jan; 155(1):254-9.
    View in: PubMed
    Score: 0.008
  88. Alper S, Warg LA, De Arras L, Flatley BR, Davidson EJ, Adams J, Smith K, Wohlford-Lenane CL, McCray PB, Pedersen BS, Schwartz DA, Yang IV. Novel Innate Immune Genes Regulating the Macrophage Response to Gram Positive Bacteria. Genetics. 2016 09; 204(1):327-36.
    View in: PubMed
    Score: 0.008
  89. Jagielo PJ, Thorne PS, Kern JA, Quinn TJ, Schwartz DA. Role of endotoxin in grain dust-induced lung inflammation in mice. Am J Physiol. 1996 Jun; 270(6 Pt 1):L1052-9.
    View in: PubMed
    Score: 0.008
  90. Schwartz DA. Grain dust, endotoxin, and airflow obstruction. Chest. 1996 Mar; 109(3 Suppl):57S-63S.
    View in: PubMed
    Score: 0.007
  91. Quinn TJ, Donham KJ, Merchant JA, Schwartz DA. Peak flow as a measure of airway dysfunction in swine confinement operators. Chest. 1995 May; 107(5):1303-8.
    View in: PubMed
    Score: 0.007
  92. Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF. The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nat Commun. 2015 Feb 17; 6:6281.
    View in: PubMed
    Score: 0.007
  93. Henao-Mart?nez AF, Agler AH, Watson AM, Hennessy C, Davidson E, Demos-Davies K, McKinsey TA, Wilson M, Schwartz DA, Yang IV. AKT network of genes and impaired myocardial contractility during murine acute Chagasic myocarditis. Am J Trop Med Hyg. 2015 Mar; 92(3):523-9.
    View in: PubMed
    Score: 0.007
  94. Schwartz DA, Donham KJ, Olenchock SA, Popendorf WJ, Van Fossen DS, Burmeister LF, Merchant JA. Determinants of longitudinal changes in spirometric function among swine confinement operators and farmers. Am J Respir Crit Care Med. 1995 Jan; 151(1):47-53.
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    Score: 0.007
  95. Schwartz DA, Thorne PS, Jagielo PJ, White GE, Bleuer SA, Frees KL. Endotoxin responsiveness and grain dust-induced inflammation in the lower respiratory tract. Am J Physiol. 1994 Nov; 267(5 Pt 1):L609-17.
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    Score: 0.007
  96. Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative genetic analysis of allergic inflammation in the murine lung. Am J Respir Cell Mol Biol. 2014 Sep; 51(3):436-45.
    View in: PubMed
    Score: 0.007
  97. Gao Z, Dosman JA, Rennie DC, Schwartz DA, Yang IV, Beach J, Senthilselvan A. NOS3 polymorphism, lung function, and exposure in swine operations: results of 2 studies. J Allergy Clin Immunol. 2014 Aug; 134(2):485-8.
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    Score: 0.007
  98. Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP. Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Am J Respir Crit Care Med. 2014 Jan 15; 189(2):214-22.
    View in: PubMed
    Score: 0.006
  99. Manners S, Alam R, Schwartz DA, Gorska MM. A mouse model links asthma susceptibility to prenatal exposure to diesel exhaust. J Allergy Clin Immunol. 2014 Jul; 134(1):63-72.
    View in: PubMed
    Score: 0.006
  100. De Arras L, Laws R, Leach SM, Pontis K, Freedman JH, Schwartz DA, Alper S. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. Genetics. 2014 Jun; 197(2):485-96.
    View in: PubMed
    Score: 0.006
  101. Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Muc5b is required for airway defence. Nature. 2014 Jan 16; 505(7483):412-6.
    View in: PubMed
    Score: 0.006
  102. Hamvas A, Deterding R, Balch WE, Schwartz DA, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS. Diffuse lung disease in children: summary of a scientific conference. Pediatr Pulmonol. 2014 Apr; 49(4):400-9.
    View in: PubMed
    Score: 0.006
  103. Lai PS, Hofmann O, Baron RM, Cernadas M, Meng QR, Bresler HS, Brass DM, Yang IV, Schwartz DA, Christiani DC, Hide W. Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. PLoS One. 2013; 8(5):e62910.
    View in: PubMed
    Score: 0.006
  104. Foster MW, Thompson JW, Que LG, Yang IV, Schwartz DA, Moseley MA, Marshall HE. Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure. J Proteome Res. 2013 May 03; 12(5):2194-205.
    View in: PubMed
    Score: 0.006
  105. Gao Z, Dosman JA, Rennie DC, Schwartz DA, Yang IV, Beach J, Senthilselvan A. Association of Toll-like receptor 2 gene polymorphisms with lung function in workers in swine operations. Ann Allergy Asthma Immunol. 2013 Jan; 110(1):44-50.e1.
    View in: PubMed
    Score: 0.006
  106. De Arras L, Seng A, Lackford B, Keikhaee MR, Bowerman B, Freedman JH, Schwartz DA, Alper S. An evolutionarily conserved innate immunity protein interaction network. J Biol Chem. 2013 Jan 18; 288(3):1967-78.
    View in: PubMed
    Score: 0.006
  107. Koeppen M, McNamee EN, Brodsky KS, Aherne CM, Faigle M, Downey GP, Colgan SP, Evans CM, Schwartz DA, Eltzschig HK. Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury. Mucosal Immunol. 2013 Jul; 6(4):762-75.
    View in: PubMed
    Score: 0.006
  108. Oakes JL, O'Connor BP, Warg LA, Burton R, Hock A, Loader J, Laflamme D, Jing J, Hui L, Schwartz DA, Yang IV. Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist. Am J Respir Cell Mol Biol. 2013 Jan; 48(1):27-34.
    View in: PubMed
    Score: 0.006
  109. Henao-Mart?nez AF, Schwartz DA, Yang IV. Chagasic cardiomyopathy, from acute to chronic: is this mediated by host susceptibility factors? Trans R Soc Trop Med Hyg. 2012 Sep; 106(9):521-7.
    View in: PubMed
    Score: 0.006
  110. Warg LA, Oakes JL, Burton R, Neidermyer AJ, Rutledge HR, Groshong S, Schwartz DA, Yang IV. The role of the E2F1 transcription factor in the innate immune response to systemic LPS. Am J Physiol Lung Cell Mol Physiol. 2012 Sep; 303(5):L391-400.
    View in: PubMed
    Score: 0.006
  111. De Arras L, Yang IV, Lackford B, Riches DW, Prekeris R, Freedman JH, Schwartz DA, Alper S. Spatiotemporal inhibition of innate immunity signaling by the Tbc1d23 RAB-GAP. J Immunol. 2012 Mar 15; 188(6):2905-13.
    View in: PubMed
    Score: 0.006
  112. Yang IV, Jiang W, Rutledge HR, Lackford B, Warg LA, De Arras L, Alper S, Schwartz DA, Pisetsky DS. Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. Mol Immunol. 2011 Sep; 48(15-16):1886-95.
    View in: PubMed
    Score: 0.005
  113. Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res. 2011 Aug; 21(8):1213-22.
    View in: PubMed
    Score: 0.005
  114. Kelada SN, Wilson MS, Tavarez U, Kubalanza K, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS. Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):817-24.
    View in: PubMed
    Score: 0.005
  115. Jin L, Xu LG, Yang IV, Davidson EJ, Schwartz DA, Wurfel MM, Cambier JC. Identification and characterization of a loss-of-function human MPYS variant. Genes Immun. 2011 Jun; 12(4):263-9.
    View in: PubMed
    Score: 0.005
  116. Rutledge HR, Jiang W, Yang J, Warg LA, Schwartz DA, Pisetsky DS, Yang IV. Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity. Innate Immun. 2012 Feb; 18(1):80-8.
    View in: PubMed
    Score: 0.005
  117. Pastva AM, Walker JK, Maddox LA, Mukherjee S, Giamberardino C, Hsia B, Potts E, Zhu H, Degan S, Sunday ME, Lawson BL, Korfhagen TR, Schwartz DA, Eu JP, Foster WM, McMahon TJ, Que L, Wright JR. Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice. Am J Respir Cell Mol Biol. 2011 Feb; 44(2):175-84.
    View in: PubMed
    Score: 0.005
  118. Garantziotis S, Li Z, Potts EN, Lindsey JY, Stober VP, Polosukhin VV, Blackwell TS, Schwartz DA, Foster WM, Hollingsworth JW. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. Am J Respir Crit Care Med. 2010 04 01; 181(7):666-75.
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    Score: 0.005
  119. Senthilselvan A, Ch?nard L, Kirychuk S, Predicala B, Schwartz DA, Burch LH, Rennie DC, Willson PJ, Dosman JA. Gender-related tumor necrosis factor-alpha responses in na?ve volunteers with Toll-like receptor 4 polymorphisms exposed in a swine confinement facility. J Interferon Cytokine Res. 2009 Dec; 29(12):781-90.
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    Score: 0.005
  120. Hollingsworth JW, Theriot BS, Li Z, Lawson BL, Sunday M, Schwartz DA, Walker JK. Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. Am J Respir Cell Mol Biol. 2010 Sep; 43(3):269-75.
    View in: PubMed
    Score: 0.005
  121. Schwartz DA, Rosenstock L, Clark JG. Monocyte-derived growth factors in asbestos-induced interstitial fibrosis. Environ Res. 1989 Aug; 49(2):283-94.
    View in: PubMed
    Score: 0.005
  122. Garantziotis S, Li Z, Potts EN, Kimata K, Zhuo L, Morgan DL, Savani RC, Noble PW, Foster WM, Schwartz DA, Hollingsworth JW. Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice. J Biol Chem. 2009 Apr 24; 284(17):11309-17.
    View in: PubMed
    Score: 0.005
  123. Driehuys B, Walker J, Pollaro J, Cofer GP, Mistry N, Schwartz D, Johnson GA. 3He MRI in mouse models of asthma. Magn Reson Med. 2007 Nov; 58(5):893-900.
    View in: PubMed
    Score: 0.004
  124. Raj JU, Aliferis C, Caprioli RM, Cowley AW, Davies PF, Duncan MW, Erle DJ, Erzurum SC, Finn PW, Ischiropoulos H, Kaminski N, Kleeberger SR, Leikauf GD, Loyd JE, Martin TR, Matalon S, Moore JH, Quackenbush J, Sabo-Attwood T, Shapiro SD, Schnitzer JE, Schwartz DA, Schwiebert LM, Sheppard D, Ware LB, Weiss ST, Whitsett JA, Wurfel MM, Matthay MA. Genomics and proteomics of lung disease: conference summary. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L45-51.
    View in: PubMed
    Score: 0.004
  125. Shofer S, Badea C, Auerbach S, Schwartz DA, Johnson GA. A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice. Exp Lung Res. 2007 Apr-May; 33(3-4):169-83.
    View in: PubMed
    Score: 0.004
  126. Bolger MS, Ross DS, Jiang H, Frank MM, Ghio AJ, Schwartz DA, Wright JR. Complement levels and activity in the normal and LPS-injured lung. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3):L748-59.
    View in: PubMed
    Score: 0.004
  127. Hollingsworth JW, Whitehead GS, Lin KL, Nakano H, Gunn MD, Schwartz DA, Cook DN. TLR4 signaling attenuates ongoing allergic inflammation. J Immunol. 2006 May 15; 176(10):5856-62.
    View in: PubMed
    Score: 0.004
  128. Suliman HB, Welty-Wolf KE, Carraway MS, Schwartz DA, Hollingsworth JW, Piantadosi CA. Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. FASEB J. 2005 Sep; 19(11):1531-3.
    View in: PubMed
    Score: 0.004
  129. Que LG, Liu L, Yan Y, Whitehead GS, Gavett SH, Schwartz DA, Stamler JS. Protection from experimental asthma by an endogenous bronchodilator. Science. 2005 Jun 10; 308(5728):1618-21.
    View in: PubMed
    Score: 0.004
  130. Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, Schwartz DA, Krishnan KR, Caron MG. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron. 2005 Jan 06; 45(1):11-6.
    View in: PubMed
    Score: 0.003
  131. El-Sayed NM, Ghedin E, Song J, MacLeod A, Bringaud F, Larkin C, Wanless D, Peterson J, Hou L, Taylor S, Tweedie A, Biteau N, Khalak HG, Lin X, Mason T, Hannick L, Caler E, Blandin G, Bartholomeu D, Simpson AJ, Kaul S, Zhao H, Pai G, Van Aken S, Utterback T, Haas B, Koo HL, Umayam L, Suh B, Gerrard C, Leech V, Qi R, Zhou S, Schwartz D, Feldblyum T, Salzberg S, Tait A, Turner CM, Ullu E, White O, Melville S, Adams MD, Fraser CM, Donelson JE. The sequence and analysis of Trypanosoma brucei chromosome II. Nucleic Acids Res. 2003 Aug 15; 31(16):4856-63.
    View in: PubMed
    Score: 0.003
  132. George CL, White ML, O'Neill ME, Thorne PS, Schwartz DA, Snyder JM. Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin. Am J Physiol Lung Cell Mol Physiol. 2003 Dec; 285(6):L1337-44.
    View in: PubMed
    Score: 0.003
  133. Walker JK, Fong AM, Lawson BL, Savov JD, Patel DD, Schwartz DA, Lefkowitz RJ. Beta-arrestin-2 regulates the development of allergic asthma. J Clin Invest. 2003 Aug; 112(4):566-74.
    View in: PubMed
    Score: 0.003
  134. Schromm AB, Lien E, Henneke P, Chow JC, Yoshimura A, Heine H, Latz E, Monks BG, Schwartz DA, Miyake K, Golenbock DT. Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med. 2001 Jul 02; 194(1):79-88.
    View in: PubMed
    Score: 0.003
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