Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Rafeul Alam and Magdalena Gorska.

 
Connection Strength
 
 
 
5.598
 
  1. Gorska MM, Alam R. Consequences of a mutation in the UNC119 gene for T cell function in idiopathic CD4 lymphopenia. Curr Allergy Asthma Rep. 2012 Oct; 12(5):396-401.
    View in: PubMed
    Score: 0.391
  2. Gorska MM, Alam R. A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia. Blood. 2012 Feb 09; 119(6):1399-406.
    View in: PubMed
    Score: 0.371
  3. Gorska MM, Goplen N, Liang Q, Alam R. Uncoordinated 119 preferentially induces Th2 differentiation and promotes the development of asthma. J Immunol. 2010 Apr 15; 184(8):4488-96.
    View in: PubMed
    Score: 0.328
  4. Gorska MM, Liang Q, Karim Z, Alam R. Uncoordinated 119 protein controls trafficking of Lck via the Rab11 endosome and is critical for immunological synapse formation. J Immunol. 2009 Aug 01; 183(3):1675-84.
    View in: PubMed
    Score: 0.313
  5. Gorska MM, Liang Q, Stafford SJ, Goplen N, Dharajiya N, Guo L, Sur S, Gaestel M, Alam R. MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation. J Exp Med. 2007 Jul 09; 204(7):1637-52.
    View in: PubMed
    Score: 0.272
  6. Gorska MM, Cen O, Liang Q, Stafford SJ, Alam R. Differential regulation of interleukin 5-stimulated signaling pathways by dynamin. J Biol Chem. 2006 May 19; 281(20):14429-39.
    View in: PubMed
    Score: 0.249
  7. Sirohi K, Sripada A, Verma M, Varma R, Liu S, Yadav S, Sahu A, Manka L, Guntur VP, Gorska MM, Alam R. CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells. Sci Adv. 2026 Feb 13; 12(7):eadj4926.
    View in: PubMed
    Score: 0.247
  8. Gorska MM, Alam R. The signaling mechanism of eosinophil activation. Expert Rev Clin Immunol. 2005 Jul; 1(2):247-56.
    View in: PubMed
    Score: 0.237
  9. Sripada A, Verma D, Varma R, Sirohi K, Kwiat C, Pathria M, Verma M, Sahu A, Guntur V, Manka L, Vestal B, Moore C, Martin RJ, Gorska MM, Cambier J, Getahun A, Alam R. Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-a signaling. J Clin Invest. 2025 Aug 15; 135(16).
    View in: PubMed
    Score: 0.236
  10. Gorska MM, Stafford SJ, Cen O, Sur S, Alam R. Unc119, a novel activator of Lck/Fyn, is essential for T cell activation. J Exp Med. 2004 Feb 02; 199(3):369-79.
    View in: PubMed
    Score: 0.214
  11. Gorska MM, Alam R. Signaling molecules as therapeutic targets in allergic diseases. J Allergy Clin Immunol. 2003 Aug; 112(2):241-50; quiz 251.
    View in: PubMed
    Score: 0.207
  12. Alam R, Gorska M. 3. Lymphocytes. J Allergy Clin Immunol. 2003 Feb; 111(2 Suppl):S476-85.
    View in: PubMed
    Score: 0.200
  13. Verma M, Michalec L, Sripada A, McKay J, Sirohi K, Verma D, Sheth D, Martin R, Dyjack N, Seibold MA, Knapp JR, Tu TH, O'Connor BP, Gorska MM, Alam R. The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma. J Exp Med. 2021 07 05; 218(7).
    View in: PubMed
    Score: 0.178
  14. Sripada A, Sirohi K, Michalec L, Guo L, McKay JT, Yadav S, Verma M, Good J, Rollins D, Gorska MM, Alam R. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021 03; 19(3):e3001063.
    View in: PubMed
    Score: 0.176
  15. Qian Q, Chowdhury BP, Sun Z, Lenberg J, Alam R, Vivier E, Gorska MM. Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B. J Clin Invest. 2020 08 03; 130(8):4133-4151.
    View in: PubMed
    Score: 0.168
  16. Liu S, Sirohi K, Verma M, McKay J, Michalec L, Sripada A, Danhorn T, Rollins D, Good J, Gorska MM, Martin RJ, Alam R. Optimal identification of human conventional and nonconventional (CRTH2-IL7Ra-) ILC2s using additional surface markers. J Allergy Clin Immunol. 2020 08; 146(2):390-405.
    View in: PubMed
    Score: 0.163
  17. Verma M, Liu S, Michalec L, Sripada A, Gorska MM, Alam R. Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations. J Allergy Clin Immunol. 2018 09; 142(3):793-803.e8.
    View in: PubMed
    Score: 0.139
  18. Lenberg J, Qian Q, Sun Z, Alam R, Gorska MM. Pre-pregnancy exposure to diesel exhaust predisposes offspring to asthma through IL-1ß and IL-17A. J Allergy Clin Immunol. 2018 03; 141(3):1118-1122.e3.
    View in: PubMed
    Score: 0.138
  19. Liu S, Verma M, Michalec L, Liu W, Sripada A, Rollins D, Good J, Ito Y, Chu H, Gorska MM, Martin RJ, Alam R. Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin. J Allergy Clin Immunol. 2018 01; 141(1):257-268.e6.
    View in: PubMed
    Score: 0.134
  20. Liu W, Liu S, Verma M, Zafar I, Good JT, Rollins D, Groshong S, Gorska MM, Martin RJ, Alam R. Mechanism of TH2/TH17-predominant and neutrophilic TH2/TH17-low subtypes of asthma. J Allergy Clin Immunol. 2017 May; 139(5):1548-1558.e4.
    View in: PubMed
    Score: 0.129
  21. Christianson CA, Goplen NP, Zafar I, Irvin C, Good JT, Rollins DR, Gorentla B, Liu W, Gorska MM, Chu H, Martin RJ, Alam R. Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33. J Allergy Clin Immunol. 2015 Jul; 136(1):59-68.e14.
    View in: PubMed
    Score: 0.115
  22. Irvin C, Zafar I, Good J, Rollins D, Christianson C, Gorska MM, Martin RJ, Alam R. Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma. J Allergy Clin Immunol. 2014 Nov; 134(5):1175-1186.e7.
    View in: PubMed
    Score: 0.111
  23. Manners S, Alam R, Schwartz DA, Gorska MM. A mouse model links asthma susceptibility to prenatal exposure to diesel exhaust. J Allergy Clin Immunol. 2014 Jul; 134(1):63-72.
    View in: PubMed
    Score: 0.106
  24. Guo L, Chen C, Liang Q, Karim MZ, Gorska MM, Alam R. Nuclear translocation of MEK1 triggers a complex T cell response through the corepressor silencing mediator of retinoid and thyroid hormone receptor. J Immunol. 2013 Jan 01; 190(1):159-67.
    View in: PubMed
    Score: 0.099
  25. Goplen N, Karim Z, Guo L, Zhuang Y, Huang H, Gorska MM, Gelfand E, Pagés G, Pouysségur J, Alam R. ERK1 is important for Th2 differentiation and development of experimental asthma. FASEB J. 2012 May; 26(5):1934-45.
    View in: PubMed
    Score: 0.093
  26. Liang Q, Guo L, Gogate S, Karim Z, Hanifi A, Leung DY, Gorska MM, Alam R. IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. J Immunol. 2010 Nov 15; 185(10):5704-13.
    View in: PubMed
    Score: 0.085
  27. Liu W, Tundwal K, Liang Q, Goplen N, Rozario S, Quayum N, Gorska M, Wenzel S, Balzar S, Alam R. Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function. Mol Cell Biol. 2010 Apr; 30(7):1783-99.
    View in: PubMed
    Score: 0.081
  28. Karim Z, Vepachedu R, Gorska M, Alam R. UNC119 inhibits dynamin and dynamin-dependent endocytic processes. Cell Signal. 2010 Jan; 22(1):128-37.
    View in: PubMed
    Score: 0.079
  29. Goplen N, Karim MZ, Liang Q, Gorska MM, Rozario S, Guo L, Alam R. Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma. J Allergy Clin Immunol. 2009 Apr; 123(4):925-32.e11.
    View in: PubMed
    Score: 0.077
  30. Liu W, Liang Q, Balzar S, Wenzel S, Gorska M, Alam R. Cell-specific activation profile of extracellular signal-regulated kinase 1/2, Jun N-terminal kinase, and p38 mitogen-activated protein kinases in asthmatic airways. J Allergy Clin Immunol. 2008 Apr; 121(4):893-902.e2.
    View in: PubMed
    Score: 0.072
  31. Goplen N, Gorska MM, Stafford SJ, Rozario S, Guo L, Liang Q, Alam R. A phosphosite screen identifies autocrine TGF-beta-driven activation of protein kinase R as a survival-limiting factor for eosinophils. J Immunol. 2008 Mar 15; 180(6):4256-64.
    View in: PubMed
    Score: 0.071
  32. Vepachedu R, Gorska MM, Singhania N, Cosgrove GP, Brown KK, Alam R. Unc119 regulates myofibroblast differentiation through the activation of Fyn and the p38 MAPK pathway. J Immunol. 2007 Jul 01; 179(1):682-90.
    View in: PubMed
    Score: 0.068
  33. Cen O, Gorska MM, Stafford SJ, Sur S, Alam R. Identification of UNC119 as a novel activator of SRC-type tyrosine kinases. J Biol Chem. 2003 Mar 07; 278(10):8837-45.
    View in: PubMed
    Score: 0.050
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)