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Connection

Makoto Miyazaki to Stearoyl-CoA Desaturase

This is a "connection" page, showing publications Makoto Miyazaki has written about Stearoyl-CoA Desaturase.

 
Connection Strength
 
 
 
4.683
 
  1. Masuda M, Miyazaki-Anzai S, Keenan AL, Okamura K, Kendrick J, Chonchol M, Offermanns S, Ntambi JM, Kuro-O M, Miyazaki M. Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity. J Clin Invest. 2015 Oct 26; 125(12):4544-58.
    View in: PubMed
    Score: 0.514
  2. Miyazaki M, Sampath H, Liu X, Flowers MT, Chu K, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun. 2009 Mar 20; 380(4):818-22.
    View in: PubMed
    Score: 0.322
  3. Miyazaki M. [Role of stearoyl-CoA desaturase in regulation of energy metabolism]. Tanpakushitsu Kakusan Koso. 2008 Sep; 53(11):1375-82.
    View in: PubMed
    Score: 0.313
  4. Miyazaki M, Flowers MT, Sampath H, Chu K, Otzelberger C, Liu X, Ntambi JM. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 2007 Dec; 6(6):484-96.
    View in: PubMed
    Score: 0.297
  5. Miyazaki M, Dobrzyn A, Elias PM, Ntambi JM. Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35):12501-6.
    View in: PubMed
    Score: 0.254
  6. Miyazaki M, Dobrzyn A, Sampath H, Lee SH, Man WC, Chu K, Peters JM, Gonzalez FJ, Ntambi JM. Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha. J Biol Chem. 2004 Aug 13; 279(33):35017-24.
    View in: PubMed
    Score: 0.233
  7. Miyazaki M, Dobrzyn A, Man WC, Chu K, Sampath H, Kim HJ, Ntambi JM. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J Biol Chem. 2004 Jun 11; 279(24):25164-71.
    View in: PubMed
    Score: 0.231
  8. Ntambi JM, Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res. 2004 Mar; 43(2):91-104.
    View in: PubMed
    Score: 0.229
  9. Miyazaki M, Jacobson MJ, Man WC, Cohen P, Asilmaz E, Friedman JM, Ntambi JM. Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem. 2003 Sep 05; 278(36):33904-11.
    View in: PubMed
    Score: 0.218
  10. Ntambi JM, Miyazaki M. Recent insights into stearoyl-CoA desaturase-1. Curr Opin Lipidol. 2003 Jun; 14(3):255-61.
    View in: PubMed
    Score: 0.217
  11. Miyazaki M, Ntambi JM. Role of stearoyl-coenzyme A desaturase in lipid metabolism. Prostaglandins Leukot Essent Fatty Acids. 2003 Feb; 68(2):113-21.
    View in: PubMed
    Score: 0.213
  12. Ting TC, Miyazaki-Anzai S, Masuda M, Levi M, Demer LL, Tintut Y, Miyazaki M. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. J Biol Chem. 2011 Jul 08; 286(27):23938-49.
    View in: PubMed
    Score: 0.094
  13. Dobrzyn P, Dobrzyn A, Miyazaki M, Ntambi JM. Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice. J Lipid Res. 2010 Aug; 51(8):2202-10.
    View in: PubMed
    Score: 0.087
  14. Liu X, Miyazaki M, Flowers MT, Sampath H, Zhao M, Chu K, Paton CM, Joo DS, Ntambi JM. Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol. 2010 Jan; 30(1):31-8.
    View in: PubMed
    Score: 0.085
  15. Mar-Heyming R, Miyazaki M, Weissglas-Volkov D, Kolaitis NA, Sadaat N, Plaisier C, Pajukanta P, Cantor RM, de Bruin TW, Ntambi JM, Lusis AJ. Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 2008 Jun; 28(6):1193-9.
    View in: PubMed
    Score: 0.076
  16. Chen C, Shah YM, Morimura K, Krausz KW, Miyazaki M, Richardson TA, Morgan ET, Ntambi JM, Idle JR, Gonzalez FJ. Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metab. 2008 Feb; 7(2):135-47.
    View in: PubMed
    Score: 0.075
  17. Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM. Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E357-64.
    View in: PubMed
    Score: 0.074
  18. Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM. Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem. 2007 Jan 26; 282(4):2483-93.
    View in: PubMed
    Score: 0.069
  19. Flowers MT, Groen AK, Oler AT, Keller MP, Choi Y, Schueler KL, Richards OC, Lan H, Miyazaki M, Kuipers F, Kendziorski CM, Ntambi JM, Attie AD. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. J Lipid Res. 2006 Dec; 47(12):2668-80.
    View in: PubMed
    Score: 0.068
  20. Chu K, Miyazaki M, Man WC, Ntambi JM. Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. Mol Cell Biol. 2006 Sep; 26(18):6786-98.
    View in: PubMed
    Score: 0.068
  21. Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes. 2006 Jul; 55(7):2032-41.
    View in: PubMed
    Score: 0.067
  22. Man WC, Miyazaki M, Chu K, Ntambi J. Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. J Lipid Res. 2006 Sep; 47(9):1928-39.
    View in: PubMed
    Score: 0.067
  23. Flowers MT, Miyazaki M, Liu X, Ntambi JM. Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance. J Clin Invest. 2006 Jun; 116(6):1478-81.
    View in: PubMed
    Score: 0.067
  24. Man WC, Miyazaki M, Chu K, Ntambi JM. Membrane topology of mouse stearoyl-CoA desaturase 1. J Biol Chem. 2006 Jan 13; 281(2):1251-60.
    View in: PubMed
    Score: 0.064
  25. Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab. 2005 Oct; 2(4):251-61.
    View in: PubMed
    Score: 0.064
  26. Biddinger SB, Almind K, Miyazaki M, Kokkotou E, Ntambi JM, Kahn CR. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes. 2005 May; 54(5):1314-23.
    View in: PubMed
    Score: 0.062
  27. Dobrzyn A, Dobrzyn P, Miyazaki M, Sampath H, Chu K, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. J Biol Chem. 2005 Jun 17; 280(24):23356-62.
    View in: PubMed
    Score: 0.062
  28. Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J Physiol Endocrinol Metab. 2005 Mar; 288(3):E599-607.
    View in: PubMed
    Score: 0.060
  29. Ntambi JM, Miyazaki M, Dobrzyn A. Regulation of stearoyl-CoA desaturase expression. Lipids. 2004 Nov; 39(11):1061-5.
    View in: PubMed
    Score: 0.060
  30. Rahman SM, Dobrzyn A, Lee SH, Dobrzyn P, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab. 2005 Feb; 288(2):E381-7.
    View in: PubMed
    Score: 0.060
  31. Lee SH, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM. Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment. J Lipid Res. 2004 Sep; 45(9):1674-82.
    View in: PubMed
    Score: 0.058
  32. Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6409-14.
    View in: PubMed
    Score: 0.058
  33. Kang K, Miyazaki M, Ntambi JM, Pariza MW. Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase1 expression and enzyme activity. Biochem Biophys Res Commun. 2004 Mar 12; 315(3):532-7.
    View in: PubMed
    Score: 0.057
  34. Rahman SM, Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Ntambi JM. Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):11110-5.
    View in: PubMed
    Score: 0.055
  35. Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science. 2002 Jul 12; 297(5579):240-3.
    View in: PubMed
    Score: 0.051
  36. Dobrzyn A, Dobrzyn P, Miyazaki M, Ntambi JM. Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues. Biochem Biophys Res Commun. 2005 Jul 08; 332(3):892-6.
    View in: PubMed
    Score: 0.016
  37. Asilmaz E, Cohen P, Miyazaki M, Dobrzyn P, Ueki K, Fayzikhodjaeva G, Soukas AA, Kahn CR, Ntambi JM, Socci ND, Friedman JM. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. J Clin Invest. 2004 Feb; 113(3):414-24.
    View in: PubMed
    Score: 0.014
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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