 Connection
Johannes Rudolph to Poly (ADP-Ribose) Polymerase-1
This is a "connection" page, showing publications Johannes Rudolph has written about Poly (ADP-Ribose) Polymerase-1.
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Connection Strength |
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4.778 |
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Rudolph J, Muthurajan UM, Palacio M, Mahadevan J, Roberts G, Erbse AH, Dyer PN, Luger K. The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol Cell. 2021 12 16; 81(24):4994-5006.e5.
Score: 0.809
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Rudolph J, Roberts G, Muthurajan UM, Luger K. HPF1 and nucleosomes mediate a dramatic switch in activity of PARP1 from polymerase to hydrolase. Elife. 2021 03 08; 10.
Score: 0.767
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Rudolph J, Roberts G, Luger K. Histone Parylation factor 1 contributes to the inhibition of PARP1 by cancer drugs. Nat Commun. 2021 02 02; 12(1):736.
Score: 0.762
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Rudolph J, Mahadevan J, Luger K. Probing the Conformational Changes Associated with DNA Binding to PARP1. Biochemistry. 2020 06 02; 59(21):2003-2011.
Score: 0.725
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Rudolph J, Mahadevan J, Dyer P, Luger K. Poly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism. Elife. 2018 08 08; 7.
Score: 0.641
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Stojanovic P, Luger K, Rudolph J. Slow Dissociation from the PARP1-HPF1 Complex Drives Inhibitor Potency. Biochemistry. 2023 08 15; 62(16):2382-2390.
Score: 0.227
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Rudolph J, Luger K. PARP1 and HPF1 team up to flag down DNA-repair machinery. Nat Struct Mol Biol. 2023 05; 30(5):568-569.
Score: 0.223
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Nakamoto MY, Rudolph J, Wuttke DS, Luger K. Nonspecific Binding of RNA to PARP1 and PARP2 Does Not Lead to Catalytic Activation. Biochemistry. 2019 12 24; 58(51):5107-5111.
Score: 0.176
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Rudolph J, Luger K. Kinetics of DNA-protein association and dissociation by stopped-flow spectroscopy. Methods Enzymol. 2019; 625:135-156.
Score: 0.169
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Mahadevan J, Rudolph J, Jha A, Tay JW, Dragavon J, Grumstrup EM, Luger K. Q-FADD: A Mechanistic Approach for Modeling the Accumulation of Proteins at Sites of DNA Damage. Biophys J. 2019 06 04; 116(11):2224-2233.
Score: 0.169
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Kellett T, Noor R, Zhou Q, Esquer H, Sala R, Stojanovic P, Rudolph J, Luger K, LaBarbera DV. HTS discovery of PARP1-HPF1 complex inhibitors in cancer. SLAS Discov. 2023 12; 28(8):394-401.
Score: 0.057
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Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S. PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites. Nucleic Acids Res. 2022 04 22; 50(7):3958-3973.
Score: 0.052
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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