Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Philippa Marrack to Animals

This is a "connection" page, showing publications Philippa Marrack has written about Animals.

 
Connection Strength
 
 
 
2.472
 
  1. Marrack P. Obsessive-Compulsive Behavior Isn't Necessarily a Bad Thing. Annu Rev Immunol. 2020 04 26; 38:1-21.
    View in: PubMed
    Score: 0.038
  2. Phalke S, Marrack P. Age (autoimmunity) associated B cells (ABCs) and their relatives. Curr Opin Immunol. 2018 12; 55:75-80.
    View in: PubMed
    Score: 0.036
  3. Marrack P. Where Have All the Flowers Gone? J Immunol. 2018 07 01; 201(1):5-6.
    View in: PubMed
    Score: 0.035
  4. Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor. Elife. 2017 11 17; 6.
    View in: PubMed
    Score: 0.033
  5. McKee AS, Marrack P. Old and new adjuvants. Curr Opin Immunol. 2017 Aug; 47:44-51.
    View in: PubMed
    Score: 0.033
  6. Munks MW, Montoya AM, Pywell CM, Talmage G, Forssen A, Campbell TL, Dodge DD, Kappler JW, Marrack P. The domestic cat antibody response to feline herpesvirus-1 increases with age. Vet Immunol Immunopathol. 2017 Jun; 188:65-70.
    View in: PubMed
    Score: 0.032
  7. Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
    View in: PubMed
    Score: 0.032
  8. Rubtsova K, Rubtsov AV, Halemano K, Li SX, Kappler JW, Santiago ML, Marrack P. T Cell Production of IFN? in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses. PLoS One. 2016; 11(11):e0166322.
    View in: PubMed
    Score: 0.031
  9. Noges LE, White J, Cambier JC, Kappler JW, Marrack P. Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines. J Immunol. 2016 08 15; 197(4):1221-30.
    View in: PubMed
    Score: 0.030
  10. Rubtsova K, Rubtsov AV, Cancro MP, Marrack P. Age-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic Immunity. J Immunol. 2015 Sep 01; 195(5):1933-7.
    View in: PubMed
    Score: 0.029
  11. Rubtsov AV, Rubtsova K, Kappler JW, Jacobelli J, Friedman RS, Marrack P. CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. J Immunol. 2015 Jul 01; 195(1):71-9.
    View in: PubMed
    Score: 0.028
  12. Rubtsova K, Rubtsov AV, van Dyk LF, Kappler JW, Marrack P. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34):E3216-24.
    View in: PubMed
    Score: 0.025
  13. Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. PLoS One. 2013; 8(4):e61775.
    View in: PubMed
    Score: 0.024
  14. Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunol Res. 2013 Mar; 55(1-3):210-6.
    View in: PubMed
    Score: 0.024
  15. McKee AS, Burchill MA, Munks MW, Jin L, Kappler JW, Friedman RS, Jacobelli J, Marrack P. Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1122-31.
    View in: PubMed
    Score: 0.024
  16. Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P. The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells. PLoS One. 2013; 8(2):e57435.
    View in: PubMed
    Score: 0.024
  17. Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein Cell. 2013 Jan; 4(1):8-16.
    View in: PubMed
    Score: 0.024
  18. Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60.
    View in: PubMed
    Score: 0.024
  19. Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 2012 Jun 29; 36(6):887-8.
    View in: PubMed
    Score: 0.023
  20. Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c? B-cell population is important for the development of autoimmunity. Blood. 2011 Aug 04; 118(5):1305-15.
    View in: PubMed
    Score: 0.021
  21. MacLeod MK, McKee AS, David A, Wang J, Mason R, Kappler JW, Marrack P. Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7914-9.
    View in: PubMed
    Score: 0.021
  22. MacLeod MK, David A, McKee AS, Crawford F, Kappler JW, Marrack P. Memory CD4 T cells that express CXCR5 provide accelerated help to B cells. J Immunol. 2011 Mar 01; 186(5):2889-96.
    View in: PubMed
    Score: 0.021
  23. Munks MW, McKee AS, Macleod MK, Powell RL, Degen JL, Reisdorph NA, Kappler JW, Marrack P. Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo. Blood. 2010 Dec 09; 116(24):5191-9.
    View in: PubMed
    Score: 0.020
  24. Marrack P, Scott-Browne J, MacLeod MK. Terminating the immune response. Immunol Rev. 2010 Jul; 236:5-10.
    View in: PubMed
    Score: 0.020
  25. MacLeod MK, Kappler JW, Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology. 2010 May; 130(1):10-5.
    View in: PubMed
    Score: 0.020
  26. Rubtsov AV, Rubtsova K, Kappler JW, Marrack P. Genetic and hormonal factors in female-biased autoimmunity. Autoimmun Rev. 2010 May; 9(7):494-8.
    View in: PubMed
    Score: 0.020
  27. McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P. Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol. 2009 Oct 01; 183(7):4403-14.
    View in: PubMed
    Score: 0.019
  28. Marrack P, McKee AS, Munks MW. Towards an understanding of the adjuvant action of aluminium. Nat Rev Immunol. 2009 04; 9(4):287-93.
    View in: PubMed
    Score: 0.018
  29. Desbien AL, Kappler JW, Marrack P. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5663-8.
    View in: PubMed
    Score: 0.018
  30. MacLeod MK, Clambey ET, Kappler JW, Marrack P. CD4 memory T cells: what are they and what can they do? Semin Immunol. 2009 Apr; 21(2):53-61.
    View in: PubMed
    Score: 0.018
  31. Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 2009 Apr 23; 458(7241):1043-6.
    View in: PubMed
    Score: 0.018
  32. Bassetti MF, White J, Kappler JW, Marrack P. Transgenic Bcl-3 slows T cell proliferation. Int Immunol. 2009 Apr; 21(4):339-48.
    View in: PubMed
    Score: 0.018
  33. MacLeod MK, McKee A, Crawford F, White J, Kappler J, Marrack P. CD4 memory T cells divide poorly in response to antigen because of their cytokine profile. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14521-6.
    View in: PubMed
    Score: 0.018
  34. Clambey ET, White J, Kappler JW, Marrack P. Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):12997-3002.
    View in: PubMed
    Score: 0.018
  35. Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Curr Opin Immunol. 2008 Apr; 20(2):203-7.
    View in: PubMed
    Score: 0.017
  36. McKee AS, MacLeod M, White J, Crawford F, Kappler JW, Marrack P. Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol. 2008 May; 20(5):659-69.
    View in: PubMed
    Score: 0.017
  37. Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008 Feb; 45(3):599-606.
    View in: PubMed
    Score: 0.017
  38. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203.
    View in: PubMed
    Score: 0.017
  39. McKee AS, Munks MW, Marrack P. How do adjuvants work? Important considerations for new generation adjuvants. Immunity. 2007 Nov; 27(5):687-90.
    View in: PubMed
    Score: 0.017
  40. Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. J Immunol. 2007 Sep 15; 179(6):3417-24.
    View in: PubMed
    Score: 0.017
  41. Marrack P. Conference summary. Proc Am Thorac Soc. 2007 Aug 15; 4(5):469-71.
    View in: PubMed
    Score: 0.016
  42. Hildeman D, Jorgensen T, Kappler J, Marrack P. Apoptosis and the homeostatic control of immune responses. Curr Opin Immunol. 2007 Oct; 19(5):516-21.
    View in: PubMed
    Score: 0.016
  43. Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. J Exp Med. 2006 Dec 25; 203(13):2953-61.
    View in: PubMed
    Score: 0.016
  44. Willis RA, Kappler JW, Marrack PC. CD8 T cell competition for dendritic cells in vivo is an early event in activation. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12063-8.
    View in: PubMed
    Score: 0.015
  45. Robertson JM, MacLeod M, Marsden VS, Kappler JW, Marrack P. Not all CD4+ memory T cells are long lived. Immunol Rev. 2006 Jun; 211:49-57.
    View in: PubMed
    Score: 0.015
  46. Zhu Y, Liu X, Hildeman D, Peyerl FW, White J, Kushnir E, Kappler J, Marrack P. Bax does not have to adopt its final form to drive T cell death. J Exp Med. 2006 May 15; 203(5):1147-52.
    View in: PubMed
    Score: 0.015
  47. Marrack P. Thymocytes and bone marrow cells in 1966: where did we go from there? J Allergy Clin Immunol. 2006 Apr; 117(4):962-4.
    View in: PubMed
    Score: 0.015
  48. Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. J Exp Med. 2006 Mar 20; 203(3):731-41.
    View in: PubMed
    Score: 0.015
  49. Marsden VS, Kappler JW, Marrack PC. Homeostasis of the memory T cell pool. Int Arch Allergy Immunol. 2006; 139(1):63-74.
    View in: PubMed
    Score: 0.015
  50. Clambey ET, van Dyk LF, Kappler JW, Marrack P. Non-malignant clonal expansions of CD8+ memory T cells in aged individuals. Immunol Rev. 2005 Jun; 205:170-89.
    View in: PubMed
    Score: 0.014
  51. Oliver PM, Wang M, Zhu Y, White J, Kappler J, Marrack P. Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7. J Exp Med. 2004 Nov 01; 200(9):1179-87.
    View in: PubMed
    Score: 0.014
  52. Zhu Y, Swanson BJ, Wang M, Hildeman DA, Schaefer BC, Liu X, Suzuki H, Mihara K, Kappler J, Marrack P. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7681-6.
    View in: PubMed
    Score: 0.013
  53. Huseby E, Kappler J, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? Eur J Immunol. 2004 May; 34(5):1243-50.
    View in: PubMed
    Score: 0.013
  54. Jordan MB, Hildeman D, Kappler J, Marrack P. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood. 2004 Aug 01; 104(3):735-43.
    View in: PubMed
    Score: 0.013
  55. Schaefer BC, Kappler JW, Kupfer A, Marrack P. Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):1004-9.
    View in: PubMed
    Score: 0.013
  56. Marrack P, Kappler J. Control of T cell viability. Annu Rev Immunol. 2004; 22:765-87.
    View in: PubMed
    Score: 0.013
  57. Hildeman DA, Mitchell T, Aronow B, Wojciechowski S, Kappler J, Marrack P. Control of Bcl-2 expression by reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15035-40.
    View in: PubMed
    Score: 0.013
  58. Huseby ES, Crawford F, White J, Kappler J, Marrack P. Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11565-70.
    View in: PubMed
    Score: 0.013
  59. Hildeman DA, Mitchell T, Kappler J, Marrack P. T cell apoptosis and reactive oxygen species. J Clin Invest. 2003 Mar; 111(5):575-81.
    View in: PubMed
    Score: 0.012
  60. Kedl RM, Kappler JW, Marrack P. Epitope dominance, competition and T cell affinity maturation. Curr Opin Immunol. 2003 Feb; 15(1):120-7.
    View in: PubMed
    Score: 0.012
  61. Mitchell TC, Teague TK, Hildeman DA, Bender J, Rees WA, Kedl RM, Swanson B, Kappler JW, Marrack P. Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival. Ann N Y Acad Sci. 2002 Dec; 975:114-31.
    View in: PubMed
    Score: 0.012
  62. Murakami M, Sakamoto A, Bender J, Kappler J, Marrack P. CD25+CD4+ T cells contribute to the control of memory CD8+ T cells. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8832-7.
    View in: PubMed
    Score: 0.012
  63. Hildeman DA, Zhu Y, Mitchell TC, Bouillet P, Strasser A, Kappler J, Marrack P. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity. 2002 Jun; 16(6):759-67.
    View in: PubMed
    Score: 0.011
  64. Kedl RM, Schaefer BC, Kappler JW, Marrack P. T cells down-modulate peptide-MHC complexes on APCs in vivo. Nat Immunol. 2002 Jan; 3(1):27-32.
    View in: PubMed
    Score: 0.011
  65. Schaefer BC, Mitchell TC, Kappler JW, Marrack P. A novel family of retroviral vectors for the rapid production of complex stable cell lines. Anal Biochem. 2001 Oct 01; 297(1):86-93.
    View in: PubMed
    Score: 0.011
  66. Marrack P, Bender J, Jordan M, Rees W, Robertson J, Schaefer BC, Kappler J. Major histocompatibility complex proteins and TCRs: do they really go together like a horse and carriage? J Immunol. 2001 Jul 15; 167(2):617-21.
    View in: PubMed
    Score: 0.011
  67. Wei P, Jordan KR, Buhrman JD, Lei J, Deng H, Marrack P, Dai S, Kappler JW, Slansky JE, Yin L. Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
    View in: PubMed
    Score: 0.011
  68. Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, White J, Zhu Y, Kappler J, Marrack P. Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol. 2001 May; 2(5):397-402.
    View in: PubMed
    Score: 0.011
  69. Ku CC, Kappler J, Marrack P. The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines. J Immunol. 2001 Feb 15; 166(4):2186-93.
    View in: PubMed
    Score: 0.010
  70. Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).
    View in: PubMed
    Score: 0.010
  71. Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
    View in: PubMed
    Score: 0.010
  72. Kedl RM, Rees WA, Hildeman DA, Schaefer B, Mitchell T, Kappler J, Marrack P. T cells compete for access to antigen-bearing antigen-presenting cells. J Exp Med. 2000 Oct 16; 192(8):1105-13.
    View in: PubMed
    Score: 0.010
  73. Marrack P, Bender J, Hildeman D, Jordan M, Mitchell T, Murakami M, Sakamoto A, Schaefer BC, Swanson B, Kappler J. Homeostasis of alpha beta TCR+ T cells. Nat Immunol. 2000 Aug; 1(2):107-11.
    View in: PubMed
    Score: 0.010
  74. Ku CC, Murakami M, Sakamoto A, Kappler J, Marrack P. Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science. 2000 Apr 28; 288(5466):675-8.
    View in: PubMed
    Score: 0.010
  75. Marrack P, Mitchell T, Hildeman D, Kedl R, Teague TK, Bender J, Rees W, Schaefer BC, Kappler J. Genomic-scale analysis of gene expression in resting and activated T cells. Curr Opin Immunol. 2000 Apr; 12(2):206-9.
    View in: PubMed
    Score: 0.010
  76. Teague TK, Schaefer BC, Hildeman D, Bender J, Mitchell T, Kappler JW, Marrack P. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. J Exp Med. 2000 Mar 20; 191(6):915-26.
    View in: PubMed
    Score: 0.010
  77. Lee S, Liu H, Hill R, Chen C, Hong X, Crawford F, Kingsley M, Zhang Q, Liu X, Chen Z, Lengeling A, Bernt KM, Marrack P, Kappler J, Zhou Q, Li CY, Xue Y, Hansen K, Zhang G. JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife. 2020 02 12; 9.
    View in: PubMed
    Score: 0.010
  78. White J, Kappler J, Marrack P. Production and characterization of T cell hybridomas. Methods Mol Biol. 2000; 134:185-93.
    View in: PubMed
    Score: 0.010
  79. Teague TK, Hildeman D, Kedl RM, Mitchell T, Rees W, Schaefer BC, Bender J, Kappler J, Marrack P. Activation changes the spectrum but not the diversity of genes expressed by T cells. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12691-6.
    View in: PubMed
    Score: 0.010
  80. Krovi SH, Kappler JW, Marrack P, Gapin L. Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22252-22261.
    View in: PubMed
    Score: 0.010
  81. Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med. 1999 Aug 02; 190(3):367-74.
    View in: PubMed
    Score: 0.009
  82. Hildeman DA, Mitchell T, Teague TK, Henson P, Day BJ, Kappler J, Marrack PC. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity. 1999 Jun; 10(6):735-44.
    View in: PubMed
    Score: 0.009
  83. Mitchell T, Kappler J, Marrack P. Bystander virus infection prolongs activated T cell survival. J Immunol. 1999 Apr 15; 162(8):4527-35.
    View in: PubMed
    Score: 0.009
  84. Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
    View in: PubMed
    Score: 0.009
  85. Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. J Exp Med. 1999 Feb 01; 189(3):521-30.
    View in: PubMed
    Score: 0.009
  86. Wilson NA, Wolf P, Ploegh H, Ignatowicz L, Kappler J, Marrack P. Invariant chain can bind MHC class II at a site other than the peptide binding groove. J Immunol. 1998 Nov 01; 161(9):4777-84.
    View in: PubMed
    Score: 0.009
  87. Marrack P, Mitchell T, Bender J, Hildeman D, Kedl R, Teague K, Kappler J. T-cell survival. Immunol Rev. 1998 Oct; 165:279-85.
    View in: PubMed
    Score: 0.009
  88. Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nat Commun. 2018 07 09; 9(1):2650.
    View in: PubMed
    Score: 0.009
  89. Vella AT, Dow S, Potter TA, Kappler J, Marrack P. Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3810-5.
    View in: PubMed
    Score: 0.009
  90. Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep. 2018 02 19; 8(1):3275.
    View in: PubMed
    Score: 0.009
  91. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167.
    View in: PubMed
    Score: 0.008
  92. Ku CC, Kotzin B, Kappler J, Marrack P. CD8+ T-cell clones in old mice. Immunol Rev. 1997 Dec; 160:139-44.
    View in: PubMed
    Score: 0.008
  93. Antonioli AH, White J, Crawford F, Renner B, Marchbank KJ, Hannan JP, Thurman JM, Marrack P, Holers VM. Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins. J Immunol. 2018 01 01; 200(1):316-326.
    View in: PubMed
    Score: 0.008
  94. Liu CP, Parker D, Kappler J, Marrack P. Selection of antigen-specific T cells by a single IEk peptide combination. J Exp Med. 1997 Nov 03; 186(9):1441-50.
    View in: PubMed
    Score: 0.008
  95. Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7717-E7726.
    View in: PubMed
    Score: 0.008
  96. Ignatowicz L, Rees W, Pacholczyk R, Ignatowicz H, Kushnir E, Kappler J, Marrack P. T cells can be activated by peptides that are unrelated in sequence to their selecting peptide. Immunity. 1997 Aug; 7(2):179-86.
    View in: PubMed
    Score: 0.008
  97. Vella A, Teague TK, Ihle J, Kappler J, Marrack P. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J Exp Med. 1997 Jul 21; 186(2):325-30.
    View in: PubMed
    Score: 0.008
  98. Rubtsov AV, Marrack P, Rubtsova K. T-bet expressing B cells - Novel target for autoimmune therapies? Cell Immunol. 2017 Nov; 321:35-39.
    View in: PubMed
    Score: 0.008
  99. Vella AT, Mitchell T, Groth B, Linsley PS, Green JM, Thompson CB, Kappler JW, Marrack P. CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo. J Immunol. 1997 May 15; 158(10):4714-20.
    View in: PubMed
    Score: 0.008
  100. Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol. 1997 Apr; 9(2):250-5.
    View in: PubMed
    Score: 0.008
  101. Ku CC, Kappler J, Marrack P. Characteristics and maintenance of CD8+ T-cell clones found in old mice. Mech Ageing Dev. 1997 Mar; 94(1-3):41-53.
    View in: PubMed
    Score: 0.008
  102. Liu CP, Lin WJ, Huang M, Kappler JW, Marrack P. Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):616-21.
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    Score: 0.008
  103. Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med. 1996 Nov 01; 184(5):1619-30.
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    Score: 0.008
  104. Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Pillars Article: Characterization of a Monoclonal Antibody Which Detects All Murine a? T Cell Receptors. J. Immunol. 1989. 142: 2736-2742. J Immunol. 2016 11 01; 197(9):3437-3443.
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    Score: 0.008
  105. Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):E5608-17.
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    Score: 0.008
  106. Ignatowicz L, Kappler J, Parker DC, Marrack P. The responses of mature T cells are not necessarily antagonized by their positively selecting peptide. J Immunol. 1996 Sep 01; 157(5):1827-31.
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    Score: 0.008
  107. Ignatowicz L, Kappler J, Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 1996 Feb 23; 84(4):521-9.
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    Score: 0.007
  108. Vella AT, Scherer MT, Schultz L, Kappler JW, Marrack P. B cells are not essential for peripheral T-cell tolerance. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):951-5.
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    Score: 0.007
  109. Scherer MT, Ignatowicz L, Pullen A, Kappler J, Marrack P. The use of mammary tumor virus (Mtv)-negative and single-Mtv mice to evaluate the effects of endogenous viral superantigens on the T cell repertoire. J Exp Med. 1995 Nov 01; 182(5):1493-504.
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    Score: 0.007
  110. Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23.
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    Score: 0.007
  111. Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. PLoS One. 2015; 10(8):e0136613.
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    Score: 0.007
  112. Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV. Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts. J Immunol. 2015 Jul 01; 195(1):46-50.
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    Score: 0.007
  113. Rubtsova K, Marrack P, Rubtsov AV. Sexual dimorphism in autoimmunity. J Clin Invest. 2015 Jun; 125(6):2187-93.
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    Score: 0.007
  114. Ignatowicz L, Winslow G, Bill J, Kappler J, Marrack P. Cell surface expression of class II MHC proteins bound by a single peptide. J Immunol. 1995 Apr 15; 154(8):3852-62.
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    Score: 0.007
  115. Vella AT, McCormack JE, Linsley PS, Kappler JW, Marrack P. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity. 1995 Mar; 2(3):261-70.
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    Score: 0.007
  116. Rubtsova K, Marrack P, Rubtsov AV. TLR7, IFN?, and T-bet: their roles in the development of ABCs in female-biased autoimmunity. Cell Immunol. 2015 Apr; 294(2):80-3.
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    Score: 0.007
  117. Kappler J, White J, Kozono H, Clements J, Marrack P. Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8462-6.
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    Score: 0.007
  118. Mack DG, Falta MT, McKee AS, Martin AK, Simonian PL, Crawford F, Gordon T, Mercer RR, Hoover MD, Marrack P, Kappler JW, Tuder RM, Fontenot AP. Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8553-8.
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    Score: 0.007
  119. David A, Crawford F, Garside P, Kappler JW, Marrack P, MacLeod M. Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7735-40.
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    Score: 0.007
  120. Marrack P, Parker DC. T-cell selection. A little of what you fancy ... Nature. 1994 Mar 31; 368(6470):397-8.
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    Score: 0.007
  121. McCormack JE, Kappler J, Marrack P. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo. Proc Natl Acad Sci U S A. 1994 Mar 15; 91(6):2086-90.
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    Score: 0.006
  122. Hugo P, Kappler JW, Godfrey DI, Marrack PC. Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion. J Immunol. 1994 Feb 01; 152(3):1022-31.
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    Score: 0.006
  123. David A, Trigunaite A, Macleod MK, Johnson AC, Marrack P, J?rgensen TN. Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice. Genes Immun. 2014 Apr-May; 15(3):153-61.
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    Score: 0.006
  124. Marrack P, Kappler J. Subversion of the immune system by pathogens. Cell. 1994 Jan 28; 76(2):323-32.
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    Score: 0.006
  125. Bedel R, Berry R, Mallevaey T, Matsuda JL, Zhang J, Godfrey DI, Rossjohn J, Kappler JW, Marrack P, Gapin L. Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E119-28.
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    Score: 0.006
  126. Callahan JE, Kappler JW, Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J Immunol. 1993 Dec 15; 151(12):6657-69.
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    Score: 0.006
  127. Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II. J Exp Med. 1993 Dec 01; 178(6):2173-83.
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    Score: 0.006
  128. Hugo P, Kappler JW, McCormack JE, Marrack P. Fibroblasts can induce thymocyte positive selection in vivo. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):10335-9.
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    Score: 0.006
  129. Hugo P, Kappler JW, Marrack PC. Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? Immunol Rev. 1993 Oct; 135:133-55.
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    Score: 0.006
  130. Marrack P, Kappler JW. How the immune system recognizes the body. Sci Am. 1993 Sep; 269(3):80-3, 86-9.
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    Score: 0.006
  131. Falta MT, Pinilla C, Mack DG, Tinega AN, Crawford F, Giulianotti M, Santos R, Clayton GM, Wang Y, Zhang X, Maier LA, Marrack P, Kappler JW, Fontenot AP. Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease. J Exp Med. 2013 Jul 01; 210(7):1403-18.
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    Score: 0.006
  132. Marrack P, Hugo P, McCormack J, Kappler J. Death and T cells. Immunol Rev. 1993 Jun; 133:119-29.
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    Score: 0.006
  133. McCormack JE, Callahan JE, Kappler J, Marrack PC. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J Immunol. 1993 May 01; 150(9):3785-92.
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    Score: 0.006
  134. Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions. Immunol Rev. 1993 Feb; 131:79-92.
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    Score: 0.006
  135. Marrack P, McCormack J, Callahan J, Ignatowicz L, Kappler J. T cell tolerance. Giles F. Filley Lecture. Chest. 1993 Feb; 103(2 Suppl):76S-78S.
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    Score: 0.006
  136. Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8a+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. J Immunol. 2013 Mar 01; 190(5):1936-47.
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    Score: 0.006
  137. Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. PLoS One. 2013; 8(1):e53789.
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    Score: 0.006
  138. Scherer MT, Ignatowicz L, Winslow GM, Kappler JW, Marrack P. Superantigens: bacterial and viral proteins that manipulate the immune system. Annu Rev Cell Biol. 1993; 9:101-28.
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    Score: 0.006
  139. Marrack P. T cell tolerance. Harvey Lect. 1993-1994; 89:147-55.
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    Score: 0.006
  140. Freed JH, Marrack P. Tissue-specific expression of self peptides bound by major histocompatibility complex class II molecules. Chem Immunol. 1993; 57:88-112.
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    Score: 0.006
  141. Kotzin BL, Leung DY, Kappler J, Marrack P. Superantigens and their potential role in human disease. Adv Immunol. 1993; 54:99-166.
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    Score: 0.006
  142. Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR a genes in an Ikaros null thymoma cell line. Eur J Immunol. 2013 Feb; 43(2):521-32.
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    Score: 0.006
  143. Hugo P, Kappler JW, Godfrey DI, Marrack PC. A cell line that can induce thymocyte positive selection. Nature. 1992 Dec 17; 360(6405):679-82.
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    Score: 0.006
  144. Winslow GM, Scherer MT, Kappler JW, Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 1992 Nov 27; 71(5):719-30.
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  145. Bjordahl RL, Gapin L, Marrack P, Refaeli Y. iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma. PLoS One. 2012; 7(8):e42635.
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    Score: 0.006
  146. Bedel R, Matsuda JL, Brigl M, White J, Kappler J, Marrack P, Gapin L. Lower TCR repertoire diversity in Traj18-deficient mice. Nat Immunol. 2012 Jul 19; 13(8):705-6.
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    Score: 0.006
  147. Finkel TH, Kappler JW, Marrack PC. Immature thymocytes are protected from deletion early in ontogeny. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3372-4.
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    Score: 0.006
  148. Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, van Dyk LF, Torres RM, Pelanda R. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proc Natl Acad Sci U S A. 2012 May 01; 109(18):E1092-100.
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    Score: 0.006
  149. Ignatowicz L, Kappler J, Marrack P. The effects of chronic infection with a superantigen-producing virus. J Exp Med. 1992 Apr 01; 175(4):917-23.
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    Score: 0.006
  150. Kappler JW, Herman A, Clements J, Marrack P. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J Exp Med. 1992 Feb 01; 175(2):387-96.
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    Score: 0.006
  151. Pullen AM, Choi Y, Kushnir E, Kappler J, Marrack P. The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens. J Exp Med. 1992 Jan 01; 175(1):41-7.
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    Score: 0.006
  152. Rubtsova K, Marrack P, Rubtsov AV. Age-associated B cells: are they the key to understanding why autoimmune diseases are more prevalent in women? Expert Rev Clin Immunol. 2012 Jan; 8(1):5-7.
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    Score: 0.006
  153. McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cell Immunol. 1991 Dec; 138(2):413-22.
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    Score: 0.006
  154. Choi YW, Kotzin B, Lafferty J, White J, Pigeon M, Kubo R, Kappler J, Marrack P. A method for production of antibodies to human T-cell receptor beta-chain variable regions. Proc Natl Acad Sci U S A. 1991 Oct 01; 88(19):8357-61.
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    Score: 0.005
  155. Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to a? T cell receptor specificity. Immunity. 2011 Oct 28; 35(4):526-35.
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    Score: 0.005
  156. Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
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    Score: 0.005
  157. Blackman MA, Finkel TH, Kappler J, Cambier J, Marrack P. Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6682-6.
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    Score: 0.005
  158. Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 2011 Jul 22; 35(1):23-33.
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    Score: 0.005
  159. Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 1991 Mar 21; 350(6315):203-7.
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    Score: 0.005
  160. Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 2011 Mar 25; 34(3):315-26.
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    Score: 0.005
  161. Marrack P, Kushnir E, Kappler J. A maternally inherited superantigen encoded by a mammary tumour virus. Nature. 1991 Feb 07; 349(6309):524-6.
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    Score: 0.005
  162. Blackman MA, Kappler JW, Marrack P. Multiple mechanisms of T cell tolerance to Mls-1a. Adv Exp Med Biol. 1991; 292:159-65.
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    Score: 0.005
  163. Herman A, Croteau G, Sekaly RP, Kappler J, Marrack P. HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells. J Exp Med. 1990 Sep 01; 172(3):709-17.
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    Score: 0.005
  164. Blackman M, Kappler J, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells. Science. 1990 Jun 15; 248(4961):1335-41.
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    Score: 0.005
  165. Blackman MA, Burgert HG, Gerhard-Burgert H, Woodland DL, Palmer E, Kappler JW, Marrack P. A role for clonal inactivation in T cell tolerance to Mls-1a. Nature. 1990 Jun 07; 345(6275):540-2.
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    Score: 0.005
  166. Stadinski BD, Zhang L, Crawford F, Marrack P, Eisenbarth GS, Kappler JW. Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):10978-83.
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    Score: 0.005
  167. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science. 1990 May 11; 248(4956):705-11.
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    Score: 0.005
  168. Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. J Immunol. 2010 May 01; 184(9):4592-5.
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    Score: 0.005
  169. Callahan JE, Herman A, Kappler JW, Marrack P. Stimulation of B10.BR T cells with superantigenic staphylococcal toxins. J Immunol. 1990 Apr 01; 144(7):2473-9.
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    Score: 0.005
  170. Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30.
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    Score: 0.005
  171. Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat Immunol. 2010 Mar; 11(3):225-31.
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    Score: 0.005
  172. Golde WT, McDuffie M, Kappler J, Marrack P. Identification of a new cell surface glycoprotein with accessory function in murine T cell responses. J Immunol. 1990 Feb 01; 144(3):804-10.
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    Score: 0.005
  173. Marrack P, Blackman M, Kushnir E, Kappler J. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med. 1990 Feb 01; 171(2):455-64.
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    Score: 0.005
  174. Marrack P, Kappler J. T cell tolerance. Semin Immunol. 1990 Jan; 2(1):45-9.
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    Score: 0.005
  175. Marrack P, Kappler JW. The T cell receptors. Chem Immunol. 1990; 49:69-81.
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    Score: 0.005
  176. Pullen AM, Potts W, Wakeland EK, Kappler J, Marrack P. Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J Exp Med. 1990 Jan 01; 171(1):49-62.
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    Score: 0.005
  177. Wang Y, Becker D, Vass T, White J, Marrack P, Kappler JW. A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling. PLoS Biol. 2009 Dec; 7(12):e1000253.
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    Score: 0.005
  178. Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, Gapin L. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 2009 Jul 17; 31(1):60-71.
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    Score: 0.005
  179. Kappler JW, Kushnir E, Marrack P. Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype. J Exp Med. 1989 May 01; 169(5):1533-41.
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    Score: 0.005
  180. Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7951-6.
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    Score: 0.005
  181. Marrack P, McCormack J, Kappler J. Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium. Nature. 1989 Apr 06; 338(6215):503-5.
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    Score: 0.005
  182. Pullen AM, Kappler JW, Marrack P. Tolerance to self antigens shapes the T-cell repertoire. Immunol Rev. 1989 Feb; 107:125-39.
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    Score: 0.005
  183. White J, Herman A, Pullen AM, Kubo R, Kappler JW, Marrack P. The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell. 1989 Jan 13; 56(1):27-35.
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    Score: 0.005
  184. Kappler JW, Pullen A, Callahan J, Choi Y, Herman A, White J, Potts W, Wakeland E, Marrack P. Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:401-7.
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    Score: 0.005
  185. Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:105-10.
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    Score: 0.005
  186. Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells. Nat Immunol. 2008 Dec; 9(12):1356-63.
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    Score: 0.004
  187. Marrack P, Kappler J. The T-cell repertoire for antigen and MHC. Immunol Today. 1988 Oct; 9(10):308-15.
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    Score: 0.004
  188. McDuffie M, Roehm N, Kappler JW, Marrack P. Involvement of major histocompatibility complex products in tolerance induction in the thymus. J Immunol. 1988 Sep 15; 141(6):1840-7.
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    Score: 0.004
  189. Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB. GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Res. 2008 Sep; 18(9):900-10.
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    Score: 0.004
  190. Gay D, Buus S, Pasternak J, Kappler J, Marrack P. The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia. Proc Natl Acad Sci U S A. 1988 Aug; 85(15):5629-33.
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    Score: 0.004
  191. Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 1988 May 20; 53(4):627-34.
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    Score: 0.004
  192. Born W, White J, Kappler J, Marrack P. Rearrangement of IgH genes in normal thymocyte development. J Immunol. 1988 May 01; 140(9):3228-32.
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    Score: 0.004
  193. Marrack P, Kappler J. T cells can distinguish between allogeneic major histocompatibility complex products on different cell types. Nature. 1988 Apr 28; 332(6167):840-3.
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    Score: 0.004
  194. Marrack P, Kushnir E, Born W, McDuffie M, Kappler J. The development of helper T cell precursors in mouse thymus. J Immunol. 1988 Apr 15; 140(8):2508-14.
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    Score: 0.004
  195. Kappler JW, Staerz U, White J, Marrack PC. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature. 1988 Mar 03; 332(6159):35-40.
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    Score: 0.004
  196. Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 2008 Mar; 28(3):324-34.
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    Score: 0.004
  197. Blackman MA, Kappler JW, Marrack P. T-cell specificity and repertoire. Immunol Rev. 1988 Jan; 101:5-19.
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    Score: 0.004
  198. Marrack P, Kappler J. The T cell receptor. Science. 1987 Nov 20; 238(4830):1073-9.
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    Score: 0.004
  199. J?rgensen TN, Roper E, Thurman JM, Marrack P, Kotzin BL. Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice. Genes Immun. 2007 Dec; 8(8):653-62.
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    Score: 0.004
  200. Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat Immunol. 2007 Oct; 8(10):1105-13.
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    Score: 0.004
  201. Khiong K, Murakami M, Kitabayashi C, Ueda N, Sawa S, Sakamoto A, Kotzin BL, Rozzo SJ, Ishihara K, Verella-Garcia M, Kappler J, Marrack P, Hirano T. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest. 2007 May; 117(5):1270-81.
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    Score: 0.004
  202. Kappler JW, Wade T, White J, Kushnir E, Blackman M, Bill J, Roehm N, Marrack P. A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product. Cell. 1987 Apr 24; 49(2):263-71.
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    Score: 0.004
  203. Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell. 1987 Apr 24; 49(2):273-80.
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    Score: 0.004
  204. Born W, McDuffie M, Roehm N, Kushnir E, White J, Thorpe D, Stefano J, Kappler J, Marrack P. Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J Immunol. 1987 Feb 15; 138(4):999-1008.
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    Score: 0.004
  205. Gay D, Kappler J, Marrack P. L3T4 interacts with class II molecules on target cells. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):127-31.
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    Score: 0.004
  206. Marrack P, McDuffie M, Born W, Blackman M, Hannum C, Kappler J. The T cell receptor: its repertoire and role in thymocyte development. Adv Exp Med Biol. 1987; 213:1-12.
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    Score: 0.004
  207. Oliver PM, Cao X, Worthen GS, Shi P, Briones N, MacLeod M, White J, Kirby P, Kappler J, Marrack P, Yang B. Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation. Immunity. 2006 Dec; 25(6):929-40.
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    Score: 0.004
  208. Golde WT, Gay D, Kappler J, Marrack P. The role of LFA-1 in class II restricted, antigen-specific T-cell responses. Cell Immunol. 1986 Nov; 103(1):73-83.
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    Score: 0.004
  209. Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat Immunol. 2006 Nov; 7(11):1191-9.
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    Score: 0.004
  210. J?rgensen TN, Thurman J, Izui S, Falta MT, Metzger TE, Flannery SA, Kappler J, Marrack P, Kotzin BL. Genetic susceptibility to polyI:C-induced IFNalpha/beta-dependent accelerated disease in lupus-prone mice. Genes Immun. 2006 Oct; 7(7):555-67.
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    Score: 0.004
  211. Gefter M, Marrack P. Immunology: development and modification of the lymphocyte repertoire. Nature. 1986 May 8-14; 321(6066):116-8.
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    Score: 0.004
  212. Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol Rev. 2006 Apr; 210:156-70.
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    Score: 0.004
  213. Gay D, Coeshott C, Golde W, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. IX. Role of accessory molecules in recognition of antigen plus isolated IA. J Immunol. 1986 Mar 15; 136(6):2026-32.
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    Score: 0.004
  214. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983. J Immunol. 2006 Mar 01; 176(5):2683-90.
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    Score: 0.004
  215. Marrack P, Kappler J. The T cell and its receptor. Sci Am. 1986 Feb; 254(2):36-45.
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    Score: 0.004
  216. Marrack P, Kappler J. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol. 1986; 38:1-30.
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    Score: 0.004
  217. Marrack P, Born W, Roehm N, Farr A, Kappler J. T cell receptors in the thymus. Biochem Soc Symp. 1986; 51:197-204.
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    Score: 0.004
  218. Yag?e J, White J, Coleclough C, Kappler J, Palmer E, Marrack P. The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell. 1985 Aug; 42(1):81-7.
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    Score: 0.004
  219. Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 2005 Jul 29; 122(2):247-60.
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    Score: 0.004
  220. Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 2005 Jun; 52(6):1885-96.
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    Score: 0.004
  221. Born W, Yag?e J, Palmer E, Kappler J, Marrack P. Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A. 1985 May; 82(9):2925-9.
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    Score: 0.004
  222. Golde WT, Kappler JW, Greenstein J, Malissen B, Hood L, Marrack P. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. J Exp Med. 1985 Mar 01; 161(3):635-40.
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    Score: 0.003
  223. Wang Y, Rubtsov A, Heiser R, White J, Crawford F, Marrack P, Kappler JW. Using a baculovirus display library to identify MHC class I mimotopes. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2476-81.
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    Score: 0.003
  224. Hoffmann PR, Kench JA, Vondracek A, Kruk E, Daleke DL, Jordan M, Marrack P, Henson PM, Fadok VA. Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo. J Immunol. 2005 Feb 01; 174(3):1393-404.
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    Score: 0.003
  225. Zlotnik A, Shimonkevitz R, Kappler J, Marrack P. Effect of prostaglandin E2 on the gamma-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas. Cell Immunol. 1985 Jan; 90(1):154-66.
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    Score: 0.003
  226. Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunol Rev. 1984 Oct; 81:161-76.
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    Score: 0.003
  227. Roehm N, Herron L, Cambier J, DiGuisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell. 1984 Sep; 38(2):577-84.
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    Score: 0.003
  228. Haskins K, Hannum C, White J, Roehm N, Kubo R, Kappler J, Marrack P. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med. 1984 Aug 01; 160(2):452-71.
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    Score: 0.003
  229. Jordan MB, Mills DM, Kappler J, Marrack P, Cambier JC. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science. 2004 Jun 18; 304(5678):1808-10.
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    Score: 0.003
  230. Marrack P. More on the T-cell receptor. Nature. 1984 May 24-30; 309(5966):310-1.
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    Score: 0.003
  231. Crawford F, Huseby E, White J, Marrack P, Kappler JW. Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. PLoS Biol. 2004 Apr; 2(4):E90.
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    Score: 0.003
  232. Gardai SJ, Hildeman DA, Frankel SK, Whitlock BB, Frasch SC, Borregaard N, Marrack P, Bratton DL, Henson PM. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J Biol Chem. 2004 May 14; 279(20):21085-95.
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    Score: 0.003
  233. Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. Annu Rev Immunol. 1984; 2:51-66.
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    Score: 0.003
  234. Zlotnik A, Shimonkevitz RP, Gefter ML, Kappler J, Marrack P. Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. J Immunol. 1983 Dec; 131(6):2814-20.
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    Score: 0.003
  235. Marrack P, Shimonkevitz R, Hannum C, Haskins K, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J Exp Med. 1983 Nov 01; 158(5):1635-46.
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    Score: 0.003
  236. Marrack P, Endres R, Shimonkevitz R, Zlotnik A, Dialynas D, Fitch F, Kappler J. The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med. 1983 Oct 01; 158(4):1077-91.
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    Score: 0.003
  237. Kappler J, Kubo R, Haskins K, White J, Marrack P. The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas. Cell. 1983 Oct; 34(3):727-37.
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    Score: 0.003
  238. Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep; 19(3):341-52.
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    Score: 0.003
  239. Ott VL, Cambier JC, Kappler J, Marrack P, Swanson BJ. Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4. Nat Immunol. 2003 Oct; 4(10):974-81.
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    Score: 0.003
  240. Marrack P, Skidmore B, Kappler JW. Binding of antigen-specific, H-2-restricted T cell hybridomas to antigen-pulsed adherent cell monolayers. J Immunol. 1983 May; 130(5):2088-92.
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    Score: 0.003
  241. Haskins K, Kubo R, White J, Pigeon M, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J Exp Med. 1983 Apr 01; 157(4):1149-69.
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    Score: 0.003
  242. Lu L, Vollmer J, Moulon C, Weltzien HU, Marrack P, Kappler J. Components of the ligand for a Ni++ reactive human T cell clone. J Exp Med. 2003 Mar 03; 197(5):567-74.
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    Score: 0.003
  243. Marrack P, Kappler J. Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas. J Exp Med. 1983 Feb 01; 157(2):404-18.
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    Score: 0.003
  244. Marrack P, Hannum C, Harris M, Haskins K, Kubo R, Pigeon M, Shimonkevitz R, White J, Kappler J. Antigen-specific, major histocompatibility complex-restricted T cell receptors. Immunol Rev. 1983; 76:131-45.
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    Score: 0.003
  245. Walker E, Warner NL, Chesnut R, Kappler J, Marrack P. Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas. J Immunol. 1982 May; 128(5):2164-9.
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    Score: 0.003
  246. Veng LM, Bjugstad KB, Freed CR, Marrack P, Clarkson ED, Bell KP, Hutt C, Zawada WM. Xenografts of MHC-deficient mouse embryonic mesencephalon improve behavioral recovery in hemiparkinsonian rats. Cell Transplant. 2002; 11(1):5-16.
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    Score: 0.003
  247. Marrack P, Graham SD, Kushnir E, Leibson HJ, Roehm N, Kappler JW. Nonspecific factors in B cell responses. Immunol Rev. 1982; 63:33-49.
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    Score: 0.003
  248. Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol. 2001 Dec 15; 214(2):110-22.
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    Score: 0.003
  249. Greenstein JL, Lord E, Kappler JW, Marrack PC. Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help. J Exp Med. 1981 Nov 01; 154(5):1608-17.
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    Score: 0.003
  250. Greenstein JL, Lord EM, Horan P, Kappler JW, Marrack P. Functional subsets of B cells defined by quantitative differences in surface I-A. J Immunol. 1981 Jun; 126(6):2419-23.
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    Score: 0.003
  251. Kappler JW, Skidmore B, White J, Marrack P. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J Exp Med. 1981 May 01; 153(5):1198-214.
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    Score: 0.003
  252. Wilson N, Fremont D, Marrack P, Kappler J. Mutations changing the kinetics of class II MHC peptide exchange. Immunity. 2001 May; 14(5):513-22.
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    Score: 0.003
  253. Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays. J Exp Med. 1980 Nov 01; 152(5):1274-88.
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    Score: 0.003
  254. Greenstein JL, Leary J, Horan P, Kappler JW, Marrack P. Flow sorting of antigen-binding B cell subsets. J Immunol. 1980 Mar; 124(3):1472-81.
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    Score: 0.002
  255. Marrack P, Kappler JW. The two high responder haplotypes to (TG)-A--L do not cross-react in the helper T cell level. J Immunol. 1980 Feb; 124(2):1002-4.
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    Score: 0.002
  256. Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J. Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):291-6.
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    Score: 0.002
  257. Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity. 1999 Oct; 11(4):411-21.
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    Score: 0.002
  258. Rees W, Bender J, Teague TK, Kedl RM, Crawford F, Marrack P, Kappler J. An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9781-6.
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    Score: 0.002
  259. Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. J Exp Med. 1979 Mar 01; 149(3):780-5.
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    Score: 0.002
  260. White J, Crawford F, Fremont D, Marrack P, Kappler J. Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. J Immunol. 1999 Mar 01; 162(5):2671-6.
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    Score: 0.002
  261. Kappler JW, Marrack P. The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med. 1978 Dec 01; 148(6):1510-22.
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    Score: 0.002
  262. Fremont DH, Crawford F, Marrack P, Hendrickson WA, Kappler J. Crystal structure of mouse H2-M. Immunity. 1998 Sep; 9(3):385-93.
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    Score: 0.002
  263. Crawford F, Kozono H, White J, Marrack P, Kappler J. Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity. 1998 Jun; 8(6):675-82.
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    Score: 0.002
  264. Marrack P, Kappler JW. The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages. J Exp Med. 1978 Jun 01; 147(6):1596-610.
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    Score: 0.002
  265. Teague TK, Marrack P, Kappler JW, Vella AT. IL-6 rescues resting mouse T cells from apoptosis. J Immunol. 1997 Jun 15; 158(12):5791-6.
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    Score: 0.002
  266. Seibel JL, Wilson N, Kozono H, Marrack P, Kappler JW. Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition. J Exp Med. 1997 Jun 02; 185(11):1919-27.
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    Score: 0.002
  267. Hamad AR, Marrack P, Kappler JW. Transcytosis of staphylococcal superantigen toxins. J Exp Med. 1997 Apr 21; 185(8):1447-54.
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    Score: 0.002
  268. Hamelmann E, Vella AT, Oshiba A, Kappler JW, Marrack P, Gelfand EW. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1350-5.
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    Score: 0.002
  269. Kappler JW, Marrack PC. Helper T cells recognise antigen and macrophage surface components simultaneously. Nature. 1976 Aug 26; 262(5571):797-9.
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    Score: 0.002
  270. Fremont DH, Hendrickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 1996 May 17; 272(5264):1001-4.
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    Score: 0.002
  271. Marrack P, Kappler JW. Antigen-specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T cells distinguished by their antigen sensitivities. J Immunol. 1976 May; 116(5):1373-8.
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    Score: 0.002
  272. Harwell L, Kappler JW, Marrack P. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources. J Immunol. 1976 May; 116(5):1379-84.
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    Score: 0.002
  273. Kozono H, Parker D, White J, Marrack P, Kappler J. Multiple binding sites for bacterial superantigens on soluble class II MHC molecules. Immunity. 1995 Aug; 3(2):187-96.
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    Score: 0.002
  274. Kappler JW, Marrack PC. Functional heterogeneity among the T-derived lymphocytes of the mouse. III. Helper and suppressor T-cells activated by concanavalin A. Cell Immunol. 1975 Jul; 18(1):9-20.
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    Score: 0.002
  275. Marrack PC, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells. J Immunol. 1975 Mar; 114(3):1116-25.
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    Score: 0.002
  276. Hamad AR, Herman A, Marrack P, Kappler JW. Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B. J Exp Med. 1994 Aug 01; 180(2):615-21.
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    Score: 0.002
  277. Kozono H, White J, Clements J, Marrack P, Kappler J. Production of soluble MHC class II proteins with covalently bound single peptides. Nature. 1994 May 12; 369(6476):151-4.
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    Score: 0.002
  278. Winslow GM, Marrack P, Kappler JW. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1994 Apr; 1(1):23-33.
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    Score: 0.002
  279. Ignatowicz L, Kappler JW, Marrack P, Scherer MT. Identification of two V beta 7-specific viral superantigens. J Immunol. 1994 Jan 01; 152(1):65-71.
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    Score: 0.002
  280. Harris TO, Grossman D, Kappler JW, Marrack P, Rich RR, Betley MJ. Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun. 1993 Aug; 61(8):3175-83.
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    Score: 0.002
  281. White J, Pullen A, Choi K, Marrack P, Kappler JW. Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor. J Exp Med. 1993 Jan 01; 177(1):119-25.
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    Score: 0.001
  282. Renz H, Bradley KL, Marrack P, Gelfand EW. T cells expressing variable elements of T-cell receptor beta 8 and beta 2 chain regulate murine IgE production. Proc Natl Acad Sci U S A. 1992 Jul 15; 89(14):6438-42.
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    Score: 0.001
  283. Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. J Exp Med. 1992 Mar 01; 175(3):847-52.
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    Score: 0.001
  284. Pullen AM, Bill J, Kubo RT, Marrack P, Kappler JW. Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta. J Exp Med. 1991 May 01; 173(5):1183-92.
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    Score: 0.001
  285. Herman A, Kappler JW, Marrack P, Pullen AM. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol. 1991; 9:745-72.
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    Score: 0.001
  286. McCormack JE, Kappler J, Marrack P, Westcott JY. Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture. J Immunol. 1991 Jan 01; 146(1):239-43.
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    Score: 0.001
  287. Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 1990 Sep 21; 62(6):1115-21.
    View in: PubMed
    Score: 0.001
  288. Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 1990 Aug 02; 346(6283):471-3.
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    Score: 0.001
  289. Pullen AM, Wade T, Marrack P, Kappler JW. Identification of the region of T cell receptor beta chain that interacts with the self-superantigen MIs-1a. Cell. 1990 Jun 29; 61(7):1365-74.
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    Score: 0.001
  290. Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science. 1990 Jun 08; 248(4960):1227-30.
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    Score: 0.001
  291. Burgert HG, White J, Weltzien HU, Marrack P, Kappler JW. Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner. J Exp Med. 1989 Dec 01; 170(6):1887-904.
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    Score: 0.001
  292. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8941-5.
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    Score: 0.001
  293. Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 1989 Sep 22; 58(6):1047-54.
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    Score: 0.001
  294. White J, Blackman M, Bill J, Kappler J, Marrack P, Gold DP, Born W. Two better cell lines for making hybridomas expressing specific T cell receptors. J Immunol. 1989 Sep 15; 143(6):1822-5.
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    Score: 0.001
  295. Kotzin BL, Kappler JW, Marrack PC, Herron LR. T cell tolerance to self antigens in New Zealand hybrid mice with lupus-like disease. J Immunol. 1989 Jul 01; 143(1):89-94.
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    Score: 0.001
  296. Pullen AM, Marrack P, Kappler JW. Evidence that Mls-2 antigens which delete V beta 3+ T cells are controlled by multiple genes. J Immunol. 1989 May 01; 142(9):3033-7.
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    Score: 0.001
  297. Finkel TH, Marrack P, Kappler JW, Kubo RT, Cambier JC. Alpha beta T cell receptor and CD3 transduce different signals in immature T cells. Implications for selection and tolerance. J Immunol. 1989 May 01; 142(9):3006-12.
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    Score: 0.001
  298. Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol. 1989 Apr 15; 142(8):2736-42.
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    Score: 0.001
  299. Blackman MA, Marrack P, Kappler J. Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science. 1989 Apr 14; 244(4901):214-7.
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    Score: 0.001
  300. Yague J, Blackman M, Born W, Marrack P, Kappler J, Palmer E. The structure of V alpha and J alpha segments in the mouse. Nucleic Acids Res. 1988 Dec 09; 16(23):11355-64.
    View in: PubMed
    Score: 0.001
  301. Carbone AM, Marrack P, Kappler JW. Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors. Science. 1988 Nov 25; 242(4882):1174-6.
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    Score: 0.001
  302. O'Brien RL, Marrack P, Storb U, Kappler JW. B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells. J Immunol. 1988 Nov 15; 141(10):3335-41.
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    Score: 0.001
  303. Pullen AM, Marrack P, Kappler JW. The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens. Nature. 1988 Oct 27; 335(6193):796-801.
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    Score: 0.001
  304. Wade T, Bill J, Marrack PC, Palmer E, Kappler JW. Molecular basis for the nonexpression of V beta 17 in some strains of mice. J Immunol. 1988 Sep 15; 141(6):2165-7.
    View in: PubMed
    Score: 0.001
  305. Fenton RG, Marrack P, Kappler JW, Kanagawa O, Seidman JG. Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene. Science. 1988 Aug 26; 241(4869):1089-92.
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    Score: 0.001
  306. Carbone AM, Marrack P, Kappler JW. Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression. J Immunol. 1988 Aug 15; 141(4):1369-75.
    View in: PubMed
    Score: 0.001
  307. van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 1988 May 06; 53(3):357-70.
    View in: PubMed
    Score: 0.001
  308. McDuffie M, Roehm N, Born W, Marrack P, Kappler JW. T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire. Transplant Proc. 1987 Dec; 19(6 Suppl 7):111-6.
    View in: PubMed
    Score: 0.001
  309. Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking. Nature. 1987 Nov 12-18; 330(6144):179-81.
    View in: PubMed
    Score: 0.001
  310. Hannum C, Marrack P, Kubo R, Kappler J. Thymocytes with the predicted properties of pre-T cells. J Exp Med. 1987 Oct 01; 166(4):874-89.
    View in: PubMed
    Score: 0.001
  311. McDuffie M, Born W, Marrack P, Kappler J. The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8728-32.
    View in: PubMed
    Score: 0.001
  312. Born W, Rathbun G, Tucker P, Marrack P, Kappler J. Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. Science. 1986 Oct 24; 234(4775):479-82.
    View in: PubMed
    Score: 0.001
  313. Kawahara DJ, Marrack P, Kappler JW. H-2-linked Ir gene control of VH determinant(s)-specific helper T cells. J Mol Cell Immunol. 1986; 2(5):255-64.
    View in: PubMed
    Score: 0.001
  314. Farr AG, Anderson SK, Marrack P, Kappler J. Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ. Cell. 1985 Dec; 43(2 Pt 1):543-50.
    View in: PubMed
    Score: 0.001
  315. Roehm NW, Carbone A, Kushnir E, Taylor BA, Riblet RJ, Marrack P, Kappler JW. The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol. 1985 Sep; 135(3):2176-82.
    View in: PubMed
    Score: 0.001
  316. Epstein R, Roehm N, Marrack P, Kappler J, Davis M, Hedrick S, Cohn M. Genetic markers of the antigen-specific T cell receptor locus. J Exp Med. 1985 May 01; 161(5):1219-24.
    View in: PubMed
    Score: 0.001
  317. Czitrom AA, Edwards S, Phillips RA, Bosma MJ, Marrack P, Kappler JW. The function of antigen-presenting cells in mice with severe combined immunodeficiency. J Immunol. 1985 Apr; 134(4):2276-80.
    View in: PubMed
    Score: 0.001
  318. Webb SR, Li JH, MacNeil I, Marrack P, Sprent J, Wilson DB. T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes. J Exp Med. 1985 Jan 01; 161(1):269-74.
    View in: PubMed
    Score: 0.001
  319. Watts TH, Brian AA, Kappler JW, Marrack P, McConnell HM. Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7564-8.
    View in: PubMed
    Score: 0.001
  320. Grey HM, Chesnut RW, Shimonkevitz R, Marrack P, Kappler J. Mechanisms of antigen processing and presentation. Immunobiology. 1984 Dec; 168(3-5):202-12.
    View in: PubMed
    Score: 0.001
  321. Shimonkevitz R, Colon S, Kappler JW, Marrack P, Grey HM. Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen. J Immunol. 1984 Oct; 133(4):2067-74.
    View in: PubMed
    Score: 0.001
  322. Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, Cambier JC. Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med. 1984 Sep 01; 160(3):679-94.
    View in: PubMed
    Score: 0.001
  323. Leibson HJ, Gefter M, Zlotnik A, Marrack P, Kappler JW. Role of gamma-interferon in antibody-producing responses. Nature. 1984 Jun 28-Jul 4; 309(5971):799-801.
    View in: PubMed
    Score: 0.001
  324. Greenstein JL, Kappler J, Marrack P, Burakoff SJ. The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma. J Exp Med. 1984 Apr 01; 159(4):1213-24.
    View in: PubMed
    Score: 0.001
  325. Folsom V, Gold DP, White J, Marrack P, Kappler J, Tonegawa S. Functional and inducible expression of a transfected murine class II major histocompatibility complex gene. Proc Natl Acad Sci U S A. 1984 Apr; 81(7):2045-9.
    View in: PubMed
    Score: 0.001
  326. Malissen B, Price MP, Goverman JM, McMillan M, White J, Kappler J, Marrack P, Pierres A, Pierres M, Hood L. Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell. 1984 Feb; 36(2):319-27.
    View in: PubMed
    Score: 0.001
  327. Wilde DB, Marrack P, Kappler J, Dialynas DP, Fitch FW. Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines. J Immunol. 1983 Nov; 131(5):2178-83.
    View in: PubMed
    Score: 0.001
  328. Kappler J, Kubo R, Haskins K, Hannum C, Marrack P, Pigeon M, McIntyre B, Allison J, Trowbridge I. The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. Cell. 1983 Nov; 35(1):295-302.
    View in: PubMed
    Score: 0.001
  329. Sunshine GH, Gold DP, Wortis HH, Marrack P, Kappler JW. Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas. J Exp Med. 1983 Nov 01; 158(5):1745-50.
    View in: PubMed
    Score: 0.001
  330. Endres RO, Marrack P, Kappler JW. An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region. J Immunol. 1983 Oct; 131(4):1656-62.
    View in: PubMed
    Score: 0.001
  331. Swain SL, Howard M, Kappler J, Marrack P, Watson J, Booth R, Wetzel GD, Dutton RW. Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med. 1983 Sep 01; 158(3):822-35.
    View in: PubMed
    Score: 0.001
  332. Shimonkevitz R, Kappler J, Marrack P, Grey H. Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. J Exp Med. 1983 Aug 01; 158(2):303-16.
    View in: PubMed
    Score: 0.001
  333. Roehm NW, Marrack P, Kappler JW. Helper signals in the plaque-forming cell response to protein-bound haptens. J Exp Med. 1983 Aug 01; 158(2):317-33.
    View in: PubMed
    Score: 0.001
  334. Zlotnik A, Roberts WK, Vasil A, Blumenthal E, Larosa F, Leibson HJ, Endres RO, Graham SD, White J, Hill J, Henson P, Klein JR, Bevan MJ, Marrack P, Kappler JW. Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine? J Immunol. 1983 Aug; 131(2):794-800.
    View in: PubMed
    Score: 0.001
  335. Daughety TW, Marrack P, Kappler JW, Chiller JM. The capacity of murine alveolar macrophages to stimulate antigen-dependent T-lymphocyte activation and proliferation. Cell Immunol. 1983 Jul 15; 79(2):374-82.
    View in: PubMed
    Score: 0.001
  336. Kronenberg M, Kraig E, Siu G, Kapp JA, Kappler J, Marrack P, Pierce CW, Hood L. Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts. J Exp Med. 1983 Jul 01; 158(1):210-27.
    View in: PubMed
    Score: 0.001
  337. White J, Haskins KM, Marrack P, Kappler J. Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies. J Immunol. 1983 Mar; 130(3):1033-7.
    View in: PubMed
    Score: 0.001
  338. Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens. J Immunol. 1983 Feb; 130(2):781-4.
    View in: PubMed
    Score: 0.001
  339. Pure E, Isakson PC, Kappler JW, Marrack P, Krammer PH, Vitetta ES. T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med. 1983 Feb 01; 157(2):600-12.
    View in: PubMed
    Score: 0.001
  340. Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, et al. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity. Immunol Rev. 1983; 74:29-56.
    View in: PubMed
    Score: 0.001
  341. Liebson HJ, Marrack P, Kappler J. B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells. J Immunol. 1982 Oct; 129(4):1398-402.
    View in: PubMed
    Score: 0.001
  342. Roehm NW, Marrack P, Kappler JW. Antigen-specific, H-2-restricted helper T cell hybridomas. J Exp Med. 1982 Jul 01; 156(1):191-204.
    View in: PubMed
    Score: 0.001
  343. Endres RO, Kushnir E, Kappler JW, Marrack P, Kinsky SC. A role for T cell helper factors in antibody responses to "T-independent" antigens. Lymphokine Res. 1982; 1(4):99-106.
    View in: PubMed
    Score: 0.001
  344. Leibson HJ, Marrack P, Kappler JW. B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor. J Exp Med. 1981 Nov 01; 154(5):1681-93.
    View in: PubMed
    Score: 0.001
  345. Harwell L, Skidmore B, Marrack P, Kappler J. Concanavalin A-inducible, interleukin-2-producing T cell hybridoma. J Exp Med. 1980 Oct 01; 152(4):893-904.
    View in: PubMed
    Score: 0.001
  346. Keller DM, Swierkosz JE, Marrack P, Kappler JW. Two types of functionally distinct, synergizing helper T cells. J Immunol. 1980 Mar; 124(3):1350-9.
    View in: PubMed
    Score: 0.001
  347. Swierkosz JE, Marrack P, Kappler JW. Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity. J Exp Med. 1979 Dec 01; 150(6):1293-309.
    View in: PubMed
    Score: 0.001
  348. Swierkosz JE, Marrack P, Kappler JW. The role of H-2-linked genes in helper T cell function. V. I-region control of helper T cell interaction with antigen-presenting macrophages. J Immunol. 1979 Aug; 123(2):654-9.
    View in: PubMed
    Score: 0.001
  349. Swierkosz JE, Rock K, Marrack P, Kappler JW. The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 products. J Exp Med. 1978 Feb 01; 147(2):554-70.
    View in: PubMed
    Score: 0.001
  350. Berkarda B, Marrack P, Kappler JW, Bakemeier RF. Effects of warfarin administration on the immune response of mice. Arzneimittelforschung. 1978; 28(8):1407-10.
    View in: PubMed
    Score: 0.001
  351. Araneo BA, Marrack P, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. VII. Conversion of T1 cells to T2 cells by antigen. J Immunol. 1977 Aug; 119(2):765-71.
    View in: PubMed
    Score: 0.001
  352. Harwell L, Marrack P, Kappler JW. Suppressor T-cell inactivation of a helper T-cell factor. Nature. 1977 Jan 06; 265(5589):57-9.
    View in: PubMed
    Score: 0.000
  353. Araneo BA, Marrack PC, Kappler JW. Functional heterongeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation. J Immunol. 1976 Dec; 117(6):2131-6.
    View in: PubMed
    Score: 0.000
  354. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. IV. Development of a model system demonstrating responsiveness of two T cell functions to HGG in vitro. J Immunol. 1976 Nov; 117(5 Pt.2):1953-9.
    View in: PubMed
    Score: 0.000
  355. Hoffeld JT, Marrack P, Kappler JW. Antigen-specific and nonspecific mediators of T cell/B cell cooperation. V. Unresponsiveness to HGG in vitro of these two T cell subpopulations. J Immunol. 1976 Nov; 117(5 Pt.2):1960-5.
    View in: PubMed
    Score: 0.000
  356. Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. V. Response kinetics of peripheral T cell subpopulations. J Immunol. 1976 Oct; 117(4):1233-7.
    View in: PubMed
    Score: 0.000
  357. Burns FD, Marrack PC, Kappler JW, Janeway CA. Functional heterogeneity among the T-derived lymphocytes of the mouse. IV. Nature of spontaneously induced suppressor cells. J Immunol. 1975 Apr; 114(4):1345-7.
    View in: PubMed
    Score: 0.000
  358. Araneo BA, Marrack PC, Kappler JW. Functional heterogeneity among the T-derived lymphocytes of the mouse. II. Sensitivity of subpopulations to anti-thymocyte serum. J Immunol. 1975 Feb; 114(2 pt 2):747-51.
    View in: PubMed
    Score: 0.000
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