 Connection
Philippa Marrack to Thymus Gland
This is a "connection" page, showing publications Philippa Marrack has written about Thymus Gland.
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Connection Strength |
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3.814 |
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Marrack P, Kappler JW. Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases? Cold Spring Harb Perspect Med. 2012 Sep 01; 2(9):a007765.
Score: 0.376
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Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 2009 Apr 23; 458(7241):1043-6.
Score: 0.295
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Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008 Feb; 45(3):599-606.
Score: 0.273
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Marrack P. Obsessive-Compulsive Behavior Isn't Necessarily a Bad Thing. Annu Rev Immunol. 2020 04 26; 38:1-21.
Score: 0.154
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Bender J, Mitchell T, Kappler J, Marrack P. CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection. J Exp Med. 1999 Aug 02; 190(3):367-74.
Score: 0.152
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Marrack P. Where Have All the Flowers Gone? J Immunol. 2018 07 01; 201(1):5-6.
Score: 0.141
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Marrack P, Kappler J. Positive selection of thymocytes bearing alpha beta T cell receptors. Curr Opin Immunol. 1997 Apr; 9(2):250-5.
Score: 0.129
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Liu CP, Kappler JW, Marrack P. Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage. J Exp Med. 1996 Nov 01; 184(5):1619-30.
Score: 0.125
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Marrack P, Parker DC. T-cell selection. A little of what you fancy ... Nature. 1994 Mar 31; 368(6470):397-8.
Score: 0.105
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Hugo P, Kappler JW, Godfrey DI, Marrack PC. Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion. J Immunol. 1994 Feb 01; 152(3):1022-31.
Score: 0.104
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Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. Comparison of peptides bound to spleen and thymus class II. J Exp Med. 1993 Dec 01; 178(6):2173-83.
Score: 0.102
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Hugo P, Kappler JW, Marrack PC. Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein? Immunol Rev. 1993 Oct; 135:133-55.
Score: 0.101
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Hugo P, Kappler JW, Godfrey DI, Marrack PC. A cell line that can induce thymocyte positive selection. Nature. 1992 Dec 17; 360(6405):679-82.
Score: 0.096
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Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunol Rev. 2012 Nov; 250(1):49-60.
Score: 0.095
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Finkel TH, Kappler JW, Marrack PC. Immature thymocytes are protected from deletion early in ontogeny. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3372-4.
Score: 0.091
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McCormack JE, Wade T, Morales H, Kappler J, Marrack P. Analysis of class II MHC structure in thymic nurse cells. Cell Immunol. 1991 Dec; 138(2):413-22.
Score: 0.089
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Koller BH, Marrack P, Kappler JW, Smithies O. Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990. J Immunol. 2010 May 01; 184(9):4592-5.
Score: 0.080
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Marrack P, McCormack J, Kappler J. Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium. Nature. 1989 Apr 06; 338(6215):503-5.
Score: 0.074
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Marrack P, Blackman M, Burgert HG, McCormack JM, Cambier J, Finkel TH, Kappler J. T-cell repertoire and thymus. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:105-10.
Score: 0.073
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McDuffie M, Roehm N, Kappler JW, Marrack P. Involvement of major histocompatibility complex products in tolerance induction in the thymus. J Immunol. 1988 Sep 15; 141(6):1840-7.
Score: 0.071
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Marrack P, Lo D, Brinster R, Palmiter R, Burkly L, Flavell RH, Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 1988 May 20; 53(4):627-34.
Score: 0.070
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Born W, White J, Kappler J, Marrack P. Rearrangement of IgH genes in normal thymocyte development. J Immunol. 1988 May 01; 140(9):3228-32.
Score: 0.070
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Marrack P, Kushnir E, Born W, McDuffie M, Kappler J. The development of helper T cell precursors in mouse thymus. J Immunol. 1988 Apr 15; 140(8):2508-14.
Score: 0.069
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Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P. Bim and Bcl-2 mutually affect the expression of the other in T cells. J Immunol. 2007 Sep 15; 179(6):3417-24.
Score: 0.067
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Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell. 1987 Apr 24; 49(2):273-80.
Score: 0.065
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Born W, McDuffie M, Roehm N, Kushnir E, White J, Thorpe D, Stefano J, Kappler J, Marrack P. Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J Immunol. 1987 Feb 15; 138(4):999-1008.
Score: 0.064
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Marrack P, Born W, Roehm N, Farr A, Kappler J. T cell receptors in the thymus. Biochem Soc Symp. 1986; 51:197-204.
Score: 0.059
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Roehm N, Herron L, Cambier J, DiGuisto D, Haskins K, Kappler J, Marrack P. The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell. 1984 Sep; 38(2):577-84.
Score: 0.054
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Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
Score: 0.037
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Liu CP, Lin WJ, Huang M, Kappler JW, Marrack P. Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):616-21.
Score: 0.032
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Silberman D, Krovi SH, Tuttle KD, Crooks J, Reisdorph R, White J, Gross J, Matsuda JL, Gapin L, Marrack P, Kappler JW. Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):E5608-17.
Score: 0.031
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Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D. Molecules in medicine mini review: the a? T cell receptor. J Mol Med (Berl). 2014 Jul; 92(7):735-41.
Score: 0.026
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Sosinowski T, White JT, Cross EW, Haluszczak C, Marrack P, Gapin L, Kedl RM. CD8a+ dendritic cell trans presentation of IL-15 to naive CD8+ T cells produces antigen-inexperienced T cells in the periphery with memory phenotype and function. J Immunol. 2013 Mar 01; 190(5):1936-47.
Score: 0.024
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Freed JH, Marrack P. Tissue-specific expression of self peptides bound by major histocompatibility complex class II molecules. Chem Immunol. 1993; 57:88-112.
Score: 0.024
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Ignatowicz L, Kappler J, Marrack P. The effects of chronic infection with a superantigen-producing virus. J Exp Med. 1992 Apr 01; 175(4):917-23.
Score: 0.023
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Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to a? T cell receptor specificity. Immunity. 2011 Oct 28; 35(4):526-35.
Score: 0.022
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Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.
Score: 0.022
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McCormack JE, Kappler J, Marrack P, Westcott JY. Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture. J Immunol. 1991 Jan 01; 146(1):239-43.
Score: 0.021
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Blackman M, Kappler J, Marrack P. The role of the T cell receptor in positive and negative selection of developing T cells. Science. 1990 Jun 15; 248(4961):1335-41.
Score: 0.020
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Blackman MA, Burgert HG, Gerhard-Burgert H, Woodland DL, Palmer E, Kappler JW, Marrack P. A role for clonal inactivation in T cell tolerance to Mls-1a. Nature. 1990 Jun 07; 345(6275):540-2.
Score: 0.020
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Marrack P, Blackman M, Kushnir E, Kappler J. The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells. J Exp Med. 1990 Feb 01; 171(2):455-64.
Score: 0.020
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Finkel TH, Cambier JC, Kubo RT, Born WK, Marrack P, Kappler JW. The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR. Cell. 1989 Sep 22; 58(6):1047-54.
Score: 0.019
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Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, Gapin L. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 2009 Jul 17; 31(1):60-71.
Score: 0.019
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Blackman MA, Marrack P, Kappler J. Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells. Science. 1989 Apr 14; 244(4901):214-7.
Score: 0.019
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Blackman MA, Kappler JW, Marrack P. T-cell specificity and repertoire. Immunol Rev. 1988 Jan; 101:5-19.
Score: 0.017
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McDuffie M, Roehm N, Born W, Marrack P, Kappler JW. T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire. Transplant Proc. 1987 Dec; 19(6 Suppl 7):111-6.
Score: 0.017
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Marrack P, Kappler J. The T cell receptor. Science. 1987 Nov 20; 238(4830):1073-9.
Score: 0.017
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Hannum C, Marrack P, Kubo R, Kappler J. Thymocytes with the predicted properties of pre-T cells. J Exp Med. 1987 Oct 01; 166(4):874-89.
Score: 0.017
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Marrack P, McDuffie M, Born W, Blackman M, Hannum C, Kappler J. The T cell receptor: its repertoire and role in thymocyte development. Adv Exp Med Biol. 1987; 213:1-12.
Score: 0.016
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Born W, Rathbun G, Tucker P, Marrack P, Kappler J. Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development. Science. 1986 Oct 24; 234(4775):479-82.
Score: 0.016
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Gefter M, Marrack P. Immunology: development and modification of the lymphocyte repertoire. Nature. 1986 May 8-14; 321(6066):116-8.
Score: 0.015
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Marrack P, Kappler J. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. Adv Immunol. 1986; 38:1-30.
Score: 0.015
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Farr AG, Anderson SK, Marrack P, Kappler J. Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ. Cell. 1985 Dec; 43(2 Pt 1):543-50.
Score: 0.015
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Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 2005 Jul 29; 122(2):247-60.
Score: 0.014
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Hannum C, Freed JH, Tarr G, Kappler J, Marrack P. Biochemistry and distribution of the T cell receptor. Immunol Rev. 1984 Oct; 81:161-76.
Score: 0.014
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Kappler JW, Marrack PC. Functional heterogeneity among the T-derived lymphocytes of the mouse. III. Helper and suppressor T-cells activated by concanavalin A. Cell Immunol. 1975 Jul; 18(1):9-20.
Score: 0.007
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Fenton RG, Marrack P, Kappler JW, Kanagawa O, Seidman JG. Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene. Science. 1988 Aug 26; 241(4869):1089-92.
Score: 0.004
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van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 1988 May 06; 53(3):357-70.
Score: 0.004
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Finkel TH, McDuffie M, Kappler JW, Marrack P, Cambier JC. Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking. Nature. 1987 Nov 12-18; 330(6144):179-81.
Score: 0.004
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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