 Connection
Dennis Roop to Skin Neoplasms
This is a "connection" page, showing publications Dennis Roop has written about Skin Neoplasms.
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Connection Strength |
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4.239 |
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Kubick BJ, Fan X, Crouch A, McCarthy R, Roop DR. Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging. J Invest Dermatol. 2020 04; 140(4):891-900.e10.
Score: 0.399
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Torchia EC, Caulin C, Acin S, Terzian T, Kubick BJ, Box NF, Roop DR. Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma. Oncogene. 2012 May 24; 31(21):2680-90.
Score: 0.230
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Kubick BJ, Roop DR. A fitness model for melanoma-initiating cells. Pigment Cell Melanoma Res. 2011 Jun; 24(3):396-7.
Score: 0.224
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Box NF, Torchia EC, Roop DR. Are stem cell niches shared for skin cancers? Pigment Cell Melanoma Res. 2010 Aug; 23(4):517-20.
Score: 0.209
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Honeycutt KA, Waikel RL, Koster MI, Wang XJ, Roop DR. The effect of c-myc on stem cell fate influences skin tumor phenotype. Mol Carcinog. 2010 Apr; 49(4):315-9.
Score: 0.207
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Torchia EC, Chen Y, Sheng H, Katayama H, Fitzpatrick J, Brinkley WR, Caulin C, Sen S, Roop DR. A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors. Cancer Res. 2009 Sep 15; 69(18):7207-15.
Score: 0.199
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Roop D, Toftg?rd R. Hedgehog in Wnterland. Nat Genet. 2008 Sep; 40(9):1040-1.
Score: 0.185
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Chen J, Roop DR. Genetically engineered mouse models for skin research: taking the next step. J Dermatol Sci. 2008 Oct; 52(1):1-12.
Score: 0.182
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Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest. 2007 Jul; 117(7):1893-901.
Score: 0.171
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Koster MI, Lu SL, White LD, Wang XJ, Roop DR. Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression. Cancer Res. 2006 Apr 15; 66(8):3981-6.
Score: 0.157
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Wang XJ, Greenhalgh DA, Donehower LA, Roop DR. Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis. Mol Carcinog. 2000 Oct; 29(2):67-75.
Score: 0.107
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Wang XJ, Liefer KM, Greenhalgh DA, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation. Mol Carcinog. 1999 Dec; 26(4):305-11.
Score: 0.101
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Brinkley BR, Roop DR. Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function. Mol Carcinog. 1998 Nov; 23(3):185-92.
Score: 0.094
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45.
Score: 0.092
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Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017 08 31; 36(35):4997-5005.
Score: 0.084
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Greenhalgh DA, Wang XJ, Roop DR. Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox. J Investig Dermatol Symp Proc. 1996 Apr; 1(2):162-76.
Score: 0.078
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Greenhalgh DA, Wang XJ, Roop DR. Multistage skin carcinogenesis in transgenic mice. Proc Assoc Am Physicians. 1995 Jul; 107(2):258-75.
Score: 0.074
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Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene. 1995 Jan 19; 10(2):279-89.
Score: 0.072
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Wang XJ, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR. Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol Carcinog. 1994 May; 10(1):15-22.
Score: 0.069
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Greenhalgh DA, Wang XJ, Dominey AM, Rothnagel JA, Roop DR. Development of transgenic mouse models of skin carcinogenesis: potential applications. Prog Clin Biol Res. 1994; 387:75-94.
Score: 0.067
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Greenhalgh DA, Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop DR. Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res. 1993 Nov 01; 53(21):5071-5.
Score: 0.066
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Rothnagel JA, Greenhalgh DA, Wang XJ, Sellheyer K, Bickenbach JR, Dominey AM, Roop DR. Transgenic models of skin diseases. Arch Dermatol. 1993 Nov; 129(11):1430-6.
Score: 0.066
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Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C. Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci. 2013 Sep 26; 14(10):19540-55.
Score: 0.066
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White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 2013 Oct; 123(10):4390-404.
Score: 0.066
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Greenhalgh DA, Rothnagel JA, Wang XJ, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop DR. Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia. Oncogene. 1993 Aug; 8(8):2145-57.
Score: 0.065
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Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Roop DR. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog. 1993; 7(2):99-110.
Score: 0.063
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Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells. 2012 Oct; 30(10):2100-13.
Score: 0.061
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Luo Y, Ellis LZ, Dallaglio K, Takeda M, Robinson WA, Robinson SE, Liu W, Lewis KD, McCarter MD, Gonzalez R, Norris DA, Roop DR, Spritz RA, Ahn NG, Fujita M. Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance. J Invest Dermatol. 2012 Oct; 132(10):2440-2450.
Score: 0.060
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Yuspa SH, Kraemer KH, Dlugosz AA, Roop DR, Kulesz-Martin M, Bickenbach JR. Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research. J Invest Dermatol. 2012 May; 132(5):1317-20.
Score: 0.060
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Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF. p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res. 2010 Dec; 23(6):781-94.
Score: 0.054
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Roop DR, Mehrel T, Krieg TM, Nakazawa H, Cheng CK, Yuspa SH. Keratin expression in mouse epidermal tumors. Carcinog Compr Surv. 1989; 11:257-71.
Score: 0.047
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Roop DR, Krieg TM, Mehrel T, Cheng CK, Yuspa SH. Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res. 1988 Jun 01; 48(11):3245-52.
Score: 0.046
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Yuspa SH, Kilkenny A, Roop DR. Aberrant differentiation in mouse skin carcinogenesis. IARC Sci Publ. 1988; (92):3-10.
Score: 0.044
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Lee S, Chari NS, Kim HW, Wang X, Roop DR, Cho SH, DiGiovanni J, McDonnell TJ. Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis. Mol Carcinog. 2007 Dec; 46(12):949-57.
Score: 0.044
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Chen J, Cheng X, Merched-Sauvage M, Caulin C, Roop DR, Koch PJ. An unexpected role for keratin 10 end domains in susceptibility to skin cancer. J Cell Sci. 2006 Dec 15; 119(Pt 24):5067-76.
Score: 0.041
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Roop DR, Lowy DR, Tambourin PE, Strickland J, Harper JR, Balaschak M, Spangler EF, Yuspa SH. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature. 1986 Oct 30-Nov 5; 323(6091):822-4.
Score: 0.041
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Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 06; 25(29):4027-32.
Score: 0.039
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Toftgard R, Yuspa SH, Roop DR. Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1985 Nov; 45(11 Pt 2):5845-50.
Score: 0.038
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Long DJ, Waikel RL, Wang XJ, Perlaky L, Roop DR, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res. 2000 Nov 01; 60(21):5913-5.
Score: 0.027
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Wang XJ, Greenhalgh DA, Roop DR. Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation. Mol Carcinog. 2000 Mar; 27(3):200-9.
Score: 0.026
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Rodr?guez-Villanueva J, Greenhalgh D, Wang XJ, Bundman D, Cho S, Delehedde M, Roop D, McDonnell TJ. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene. 1998 Feb 19; 16(7):853-63.
Score: 0.022
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Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R. MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015 Jul 23; 4.
Score: 0.019
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Kulesz-Martin MF, Lisafeld B, Paterson J, Driscoll D, Shudo K, Roop DR, Kisiel ND. Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model. Cancer Detect Prev. 1995; 19(4):355-66.
Score: 0.018
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Sundberg JP, Erickson AA, Roop DR, Binder RL. Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10. Cancer Res. 1994 Mar 01; 54(5):1344-51.
Score: 0.017
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Robles AI, Gimenez-Conti IB, Roop D, Slaga TJ, Conti CJ. Low frequency of codon 61 Ha-ras mutations and lack of keratin 13 expression in 7,12-dimethylbenz[a]-anthracene-induced hamster skin tumors. Mol Carcinog. 1993; 7(2):94-8.
Score: 0.016
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Kartasova T, Roop DR, Yuspa SH. Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors. Mol Carcinog. 1992; 6(1):18-25.
Score: 0.015
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Huitfeldt HS, Heyden A, Clausen OP, Thrane EV, Roop D, Yuspa SH. Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors. Carcinogenesis. 1991 Nov; 12(11):2063-7.
Score: 0.014
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Sundberg JP, Hanson CA, Roop DR, Brown KS, Bedigian HG. Myoepitheliomas in inbred laboratory mice. Vet Pathol. 1991 Jul; 28(4):313-23.
Score: 0.014
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Yuspa SH, Kilkenny A, Cheng C, Roop D, Hennings H, Kruszewski F, Lee E, Strickland J, Greenhalgh DA. Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis. Environ Health Perspect. 1991 Jun; 93:3-10.
Score: 0.014
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Gimenez-Conti I, Aldaz CM, Bianchi AB, Roop DR, Slaga TJ, Conti CJ. Early expression of type I K13 keratin in the progression of mouse skin papillomas. Carcinogenesis. 1990 Nov; 11(11):1995-9.
Score: 0.013
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Yuspa SH, Hennings H, Roop D, Strickland J, Greenhalgh DA. The malignant conversion step of mouse skin carcinogenesis. Environ Health Perspect. 1990 Aug; 88:193-5.
Score: 0.013
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Aldaz CM, Conti CJ, Larcher F, Trono D, Roop DR, Chesner J, Whitehead T, Slaga TJ. Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas. Cancer Res. 1988 Jun 01; 48(11):3253-7.
Score: 0.011
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Hawley-Nelson P, Roop DR, Cheng CK, Krieg TM, Yuspa SH. Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis. Mol Carcinog. 1988; 1(3):202-11.
Score: 0.011
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Nischt R, Roop DR, Mehrel T, Yuspa SH, Rentrop M, Winter H, Schweizer J. Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia. Mol Carcinog. 1988; 1(2):96-108.
Score: 0.011
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Toftgard R, Roop DR, Yuspa SH. Proto-oncogene expression during two-stage carcinogenesis in mouse skin. Carcinogenesis. 1985 Apr; 6(4):655-7.
Score: 0.009
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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