 Connection
Dennis Roop to Epidermis
This is a "connection" page, showing publications Dennis Roop has written about Epidermis.
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Connection Strength |
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8.871 |
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Kubick BJ, Fan X, Crouch A, McCarthy R, Roop DR. Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging. J Invest Dermatol. 2020 04; 140(4):891-900.e10.
Score: 0.597
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Ishitsuka Y, Roop DR. Loricrin Confers Photoprotective Function against UVB in Corneocytes. J Invest Dermatol. 2018 12; 138(12):2684-2687.
Score: 0.547
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Rice RH, Durbin-Johnson BP, Ishitsuka Y, Salemi M, Phinney BS, Rocke DM, Roop DR. Proteomic Analysis of Loricrin Knockout Mouse Epidermis. J Proteome Res. 2016 08 05; 15(8):2560-6.
Score: 0.480
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Ishitsuka Y, Huebner AJ, Rice RH, Koch PJ, Speransky VV, Steven AC, Roop DR. Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin. J Invest Dermatol. 2016 08; 136(8):1656-1663.
Score: 0.473
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Huebner AJ, Dai D, Morasso M, Schmidt EE, Schäfer M, Werner S, Roop DR. Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11; 23(6):1238-46.
Score: 0.373
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Koster MI, Dai D, Marinari B, Sano Y, Costanzo A, Karin M, Roop DR. p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3255-60.
Score: 0.250
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Koster MI, Dai D, Roop DR. Conflicting roles for p63 in skin development and carcinogenesis. Cell Cycle. 2007 Feb 01; 6(3):269-73.
Score: 0.249
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Koster MI, Roop DR. Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol. 2007; 23:93-113.
Score: 0.247
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Koster MI, Kim S, Huang J, Williams T, Roop DR. TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol. 2006 Jan 01; 289(1):253-61.
Score: 0.229
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Koster MI, Roop DR. Asymmetric cell division in skin development: a new look at an old observation. Dev Cell. 2005 Oct; 9(4):444-6.
Score: 0.227
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Koster MI, Roop DR. Genetic pathways required for epidermal morphogenesis. Eur J Cell Biol. 2004 Dec; 83(11-12):625-9.
Score: 0.214
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Koch PJ, Roop DR. The role of keratins in epidermal development and homeostasis--going beyond the obvious. J Invest Dermatol. 2004 Nov; 123(5):x-xi.
Score: 0.213
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Goldstein NB, Steel A, Tomb L, Berk Z, Hu J, Balaya V, Hoaglin L, Ganuthula K, Patel M, Mbika E, Robinson WA, Roop DR, Norris DA, Birlea SA. Vitiligo non-responding lesions to narrow band UVB have intriguing cellular and molecular abnormalities that may prevent epidermal repigmentation. Pigment Cell Melanoma Res. 2024 05; 37(3):378-390.
Score: 0.202
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Koster MI, Roop DR. The role of p63 in development and differentiation of the epidermis. J Dermatol Sci. 2004 Feb; 34(1):3-9.
Score: 0.202
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Cao T, Tsai SY, O'Malley BW, Wang XJ, Roop DR. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80.
Score: 0.180
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Ishitsuka Y, Roop DR. Loricrin at the Boundary between Inside and Outside. Biomolecules. 2022 05 06; 12(5).
Score: 0.179
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Cao T, Wang XJ, Roop DR. Regulated cutaneous gene delivery: the skin as a bioreactor. Hum Gene Ther. 2000 Nov 01; 11(16):2297-300.
Score: 0.161
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Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC, Roop DR. Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol. 2000 Oct 16; 151(2):389-400.
Score: 0.161
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Liefer KM, Koster MI, Wang XJ, Yang A, McKeon F, Roop DR. Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res. 2000 Aug 01; 60(15):4016-20.
Score: 0.158
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Ogawa T, Ishitsuka Y, Nakamura Y, Kubota N, Saito A, Fujisawa Y, Watanabe R, Okiyama N, Suga Y, Roop DR, Fujimoto M. NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy. J Immunol. 2020 08 15; 205(4):907-914.
Score: 0.158
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Ishitsuka Y, Roop DR. Loricrin: Past, Present, and Future. Int J Mol Sci. 2020 Mar 25; 21(7).
Score: 0.155
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Wojcik SM, Imakado S, Seki T, Longley MA, Petherbridge L, Bundman DS, Bickenbach JR, Rothnagel JA, Roop DR. Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle. Differentiation. 1999 Oct; 65(2):97-112.
Score: 0.150
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Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR. The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation. 1999 Oct; 65(2):119-30.
Score: 0.150
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Waikel RL, Wang XJ, Roop DR. Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene. 1999 Aug 26; 18(34):4870-8.
Score: 0.149
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Wang XJ, Liefer KM, Tsai S, O'Malley BW, Roop DR. Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8483-8.
Score: 0.147
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Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2386-91.
Score: 0.125
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Greenhalgh DA, Wang XJ, Donehower LA, Roop DR. Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res. 1996 Oct 01; 56(19):4413-23.
Score: 0.121
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Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR. Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS One. 2016; 11(8):e0161465.
Score: 0.121
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Kumar V, Bouameur JE, Bär J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Löffler-Wirth H, Seibel P, Magin TM. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 07; 211(5):1057-75.
Score: 0.115
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Greenhalgh DA, Rothnagel JA, Roop DR. Epidermis: an attractive target tissue for gene therapy. J Invest Dermatol. 1994 Nov; 103(5 Suppl):63S-69S.
Score: 0.106
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Rorke EA, Adhikary G, Young CA, Roop DR, Eckert RL. Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype. J Invest Dermatol. 2015 Jan; 135(1):170-180.
Score: 0.105
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Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR. Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene. J Invest Dermatol. 1993 Oct; 101(4):506-13.
Score: 0.099
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Greenhalgh DA, Rothnagel JA, Wang XJ, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop DR. Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia. Oncogene. 1993 Aug; 8(8):2145-57.
Score: 0.098
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Bilousova G, Chen J, Roop DR. Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage. J Invest Dermatol. 2011 Apr; 131(4):857-64.
Score: 0.081
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Kim S, Choi IF, Quante JR, Zhang L, Roop DR, Koster MI. p63 directly induces expression of Alox12, a regulator of epidermal barrier formation. Exp Dermatol. 2009 Dec; 18(12):1016-21.
Score: 0.076
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Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA. Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 01; 317(1):187-95.
Score: 0.067
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Shah VR, Koster MI, Roop DR, Spencer DM, Wei L, Li Q, Schwartz RJ, Chang J. Double-inducible gene activation system for caspase 3 and 9 in epidermis. Genesis. 2007 Apr; 45(4):194-9.
Score: 0.063
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Geng S, Mezentsev A, Kalachikov S, Raith K, Roop DR, Panteleyev AA. Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function. J Cell Sci. 2006 Dec 01; 119(Pt 23):4901-12.
Score: 0.061
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Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 01; 299(1):122-36.
Score: 0.060
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Koster MI, Kim S, Roop DR. P63 deficiency: a failure of lineage commitment or stem cell maintenance? J Investig Dermatol Symp Proc. 2005 Nov; 10(2):118-23.
Score: 0.057
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Koster MI, Roop DR. p63 and epithelial appendage development. Differentiation. 2004 Oct; 72(8):364-70.
Score: 0.053
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Honeycutt KA, Koster MI, Roop DR. Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease. J Investig Dermatol Symp Proc. 2004 Sep; 9(3):261-8.
Score: 0.053
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Matsumoto T, Kiguchi K, Jiang J, Carbajal S, Ruffino L, Beltrán L, Wang XJ, Roop DR, DiGiovanni J. Development of transgenic mice that inducibly express an active form of c-Src in the epidermis. Mol Carcinog. 2004 Aug; 40(4):189-200.
Score: 0.052
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Sil AK, Maeda S, Sano Y, Roop DR, Karin M. IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature. 2004 Apr 08; 428(6983):660-4.
Score: 0.051
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Koster MI, Roop DR. Transgenic mouse models provide new insights into the role of p63 in epidermal development. Cell Cycle. 2004 Apr; 3(4):411-3.
Score: 0.051
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Arin MJ, Roop DR. Inducible mouse models for inherited skin diseases: implications for skin gene therapy. Cells Tissues Organs. 2004; 177(3):160-8.
Score: 0.050
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Steinert PM, Steven AC, Roop DR. Structural features of epidermal keratin filaments reassembled in vitro. J Invest Dermatol. 1983 Jul; 81(1 Suppl):86s-90s.
Score: 0.048
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Roop DR, Hawley-Nelson P, Cheng CK, Yuspa SH. Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A. 1983 Feb; 80(3):716-20.
Score: 0.047
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Zhou Z, Wang D, Wang XJ, Roop DR. In utero activation of K5.CrePR1 induces gene deletion. Genesis. 2002 Feb; 32(2):191-2.
Score: 0.044
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Jarnik M, de Viragh PA, Schärer E, Bundman D, Simon MN, Roop DR, Steven AC. Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system. J Invest Dermatol. 2002 Jan; 118(1):102-9.
Score: 0.044
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Wang XJ, Greenhalgh DA, Donehower LA, Roop DR. Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis. Mol Carcinog. 2000 Oct; 29(2):67-75.
Score: 0.040
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Wojcik SM, Bundman DS, Roop DR. Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol. 2000 Jul; 20(14):5248-55.
Score: 0.039
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Berton TR, Wang XJ, Zhou Z, Kellendonk C, Schütz G, Tsai S, Roop DR. Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis. 2000 Feb; 26(2):160-1.
Score: 0.038
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Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 1999 Apr 22; 398(6729):708-13.
Score: 0.036
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45.
Score: 0.034
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Borkowski TA, Letterio JJ, Mackall CL, Saitoh A, Wang XJ, Roop DR, Gress RE, Udey MC. A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest. 1997 Aug 01; 100(3):575-81.
Score: 0.032
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Attar PS, Wertz PW, McArthur M, Imakado S, Bickenbach JR, Roop DR. Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function. Mol Endocrinol. 1997 Jun; 11(6):792-800.
Score: 0.032
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Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation. 1996 Dec; 61(2):129-39.
Score: 0.031
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Ishida-Yamamoto A, Eady RA, Watt FM, Roop DR, Hohl D, Iizuka H. Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem. 1996 Feb; 44(2):167-75.
Score: 0.029
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Greenhalgh DA, Wang XJ, Eckhardt JN, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy. Cell Growth Differ. 1995 May; 6(5):579-86.
Score: 0.028
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Goldstein NB, Koster MI, Hoaglin LG, Spoelstra NS, Kechris KJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA. Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors. J Invest Dermatol. 2015 Aug; 135(8):2068-2076.
Score: 0.027
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Bickenbach JR, Greer JM, Bundman DS, Rothnagel JA, Roop DR. Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. J Invest Dermatol. 1995 Mar; 104(3):405-10.
Score: 0.027
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Heyden A, Lützow-Holm C, Clausen OP, Thrane EV, Brandtzaeg P, Roop DR, Yuspa SH, Huitfeldt HS. Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution. Differentiation. 1994 Sep; 57(3):187-93.
Score: 0.026
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Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR. Genetic disorders of keratin: are scarring alopecias a sub-set? J Dermatol Sci. 1994 Jul; 7 Suppl:S164-9.
Score: 0.026
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Greenhalgh DA, Wang XJ, Rothnagel JA, Eckhardt JN, Quintanilla MI, Barber JL, Bundman DS, Longley MA, Schlegel R, Roop DR. Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas. Cell Growth Differ. 1994 Jun; 5(6):667-75.
Score: 0.026
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Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C. Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci. 2013 Sep 26; 14(10):19540-55.
Score: 0.025
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Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ. Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis. Cell Death Differ. 2013 Aug; 20(8):1080-8.
Score: 0.024
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Ishida-Yamamoto A, Hohl D, Roop DR, Iizuka H, Eady RA. Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia. Arch Dermatol Res. 1993; 285(8):491-8.
Score: 0.023
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Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA. A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012; 7(11):e50634.
Score: 0.023
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Yuspa SH, Kilkenny A, Cheng C, Roop D, Hennings H, Kruszewski F, Lee E, Strickland J, Greenhalgh DA. Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis. Environ Health Perspect. 1991 Jun; 93:3-10.
Score: 0.021
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Hohl D, Mehrel T, Lichti U, Turner ML, Roop DR, Steinert PM. Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem. 1991 Apr 05; 266(10):6626-36.
Score: 0.021
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Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J. Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb; 131(2):302-10.
Score: 0.020
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Yuspa SH, Kilkenny AE, Steinert PM, Roop DR. Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol. 1989 Sep; 109(3):1207-17.
Score: 0.019
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Yuspa SH, Hennings H, Tucker RW, Jaken S, Kilkenny AE, Roop DR. Signal transduction for proliferation and differentiation in keratinocytes. Ann N Y Acad Sci. 1988; 548:191-6.
Score: 0.017
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Lee S, Chari NS, Kim HW, Wang X, Roop DR, Cho SH, DiGiovanni J, McDonnell TJ. Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis. Mol Carcinog. 2007 Dec; 46(12):949-57.
Score: 0.016
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Roop DR, Huitfeldt H, Kilkenny A, Yuspa SH. Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins. Differentiation. 1987; 35(2):143-50.
Score: 0.015
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Roop DR, Lowy DR, Tambourin PE, Strickland J, Harper JR, Balaschak M, Spangler EF, Yuspa SH. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature. 1986 Oct 30-Nov 5; 323(6091):822-4.
Score: 0.015
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Hawley-Nelson P, Roop DR, Cheng CK, Yuspa SH. Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures. J Invest Dermatol. 1986 Oct; 87(4):454-9.
Score: 0.015
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Johnson LD, Idler WW, Zhou XM, Roop DR, Steinert PM. Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A. 1985 Apr; 82(7):1896-900.
Score: 0.014
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Cao T, He W, Roop DR, Wang XJ. K14-GLp65 transactivator induces transgene expression in embryonic epidermis. Genesis. 2002 Feb; 32(2):189-90.
Score: 0.011
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Sundberg JP, Dunstan RW, Roop DR, Beamer WG. Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype. J Invest Dermatol. 1994 May; 102(5):781-8.
Score: 0.006
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Kartasova T, Roop DR, Holbrook KA, Yuspa SH. Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network. J Cell Biol. 1993 Mar; 120(5):1251-61.
Score: 0.006
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Steven AC, Bisher ME, Roop DR, Steinert PM. Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes. J Struct Biol. 1990 Jul-Sep; 104(1-3):150-62.
Score: 0.005
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Ansel JC, Luger TA, Lowry D, Perry P, Roop DR, Mountz JD. The expression and modulation of IL-1 alpha in murine keratinocytes. J Immunol. 1988 Apr 01; 140(7):2274-8.
Score: 0.004
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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