 Connection
Dennis Roop to Animals
This is a "connection" page, showing publications Dennis Roop has written about Animals.
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1.649 |
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Ishitsuka Y, Roop DR. Loricrin: Past, Present, and Future. Int J Mol Sci. 2020 Mar 25; 21(7).
Score: 0.040
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Kubick BJ, Fan X, Crouch A, McCarthy R, Roop DR. Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging. J Invest Dermatol. 2020 04; 140(4):891-900.e10.
Score: 0.038
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Ishitsuka Y, Roop DR. Loricrin Confers Photoprotective Function against?UVB in Corneocytes. J Invest Dermatol. 2018 12; 138(12):2684-2687.
Score: 0.035
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Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR. Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS One. 2016; 11(8):e0161465.
Score: 0.031
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Rice RH, Durbin-Johnson BP, Ishitsuka Y, Salemi M, Phinney BS, Rocke DM, Roop DR. Proteomic Analysis of Loricrin Knockout Mouse Epidermis. J Proteome Res. 2016 08 05; 15(8):2560-6.
Score: 0.031
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Ishitsuka Y, Huebner AJ, Rice RH, Koch PJ, Speransky VV, Steven AC, Roop DR. Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for?the Loss of Loricrin. J Invest Dermatol. 2016 08; 136(8):1656-1663.
Score: 0.030
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Bilousova G, Roop DR. Generation of functional multipotent keratinocytes from mouse induced pluripotent stem cells. Methods Mol Biol. 2013; 961:337-50.
Score: 0.024
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Huebner AJ, Dai D, Morasso M, Schmidt EE, Sch?fer M, Werner S, Roop DR. Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11; 23(6):1238-46.
Score: 0.024
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Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR. Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan; 133(1):78-86.
Score: 0.023
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Torchia EC, Caulin C, Acin S, Terzian T, Kubick BJ, Box NF, Roop DR. Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma. Oncogene. 2012 May 24; 31(21):2680-90.
Score: 0.022
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Kubick BJ, Roop DR. A fitness model for melanoma-initiating cells. Pigment Cell Melanoma Res. 2011 Jun; 24(3):396-7.
Score: 0.021
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Bilousova G, Chen J, Roop DR. Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage. J Invest Dermatol. 2011 Apr; 131(4):857-64.
Score: 0.021
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Box NF, Torchia EC, Roop DR. Are stem cell niches shared for skin cancers? Pigment Cell Melanoma Res. 2010 Aug; 23(4):517-20.
Score: 0.020
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Honeycutt KA, Waikel RL, Koster MI, Wang XJ, Roop DR. The effect of c-myc on stem cell fate influences skin tumor phenotype. Mol Carcinog. 2010 Apr; 49(4):315-9.
Score: 0.020
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Torchia EC, Chen Y, Sheng H, Katayama H, Fitzpatrick J, Brinkley WR, Caulin C, Sen S, Roop DR. A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors. Cancer Res. 2009 Sep 15; 69(18):7207-15.
Score: 0.019
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Koster MI, Marinari B, Payne AS, Kantaputra PN, Costanzo A, Roop DR. DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1942-7.
Score: 0.019
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Koster MI, Roop DR. Sorting out the p63 signaling network. J Invest Dermatol. 2008 Jul; 128(7):1617-9.
Score: 0.018
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Chen J, Roop DR. Genetically engineered mouse models for skin research: taking the next step. J Dermatol Sci. 2008 Oct; 52(1):1-12.
Score: 0.017
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Chen J, Jaeger K, Den Z, Koch PJ, Sundberg JP, Roop DR. Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita. J Invest Dermatol. 2008 Feb; 128(2):270-9.
Score: 0.017
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Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest. 2007 Jul; 117(7):1893-901.
Score: 0.016
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Koster MI, Dai D, Marinari B, Sano Y, Costanzo A, Karin M, Roop DR. p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3255-60.
Score: 0.016
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Koster MI, Dai D, Roop DR. Conflicting roles for p63 in skin development and carcinogenesis. Cell Cycle. 2007 Feb 01; 6(3):269-73.
Score: 0.016
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Buitrago W, Roop DR. Oct-4: the almighty POUripotent regulator? J Invest Dermatol. 2007 Feb; 127(2):260-2.
Score: 0.016
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Koster MI, Roop DR. Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol. 2007; 23:93-113.
Score: 0.016
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Koster MI, Lu SL, White LD, Wang XJ, Roop DR. Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression. Cancer Res. 2006 Apr 15; 66(8):3981-6.
Score: 0.015
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Koster MI, Kim S, Huang J, Williams T, Roop DR. TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol. 2006 Jan 01; 289(1):253-61.
Score: 0.015
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Koster MI, Kim S, Roop DR. P63 deficiency: a failure of lineage commitment or stem cell maintenance? J Investig Dermatol Symp Proc. 2005 Nov; 10(2):118-23.
Score: 0.015
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Koster MI, Roop DR. Asymmetric cell division in skin development: a new look at an old observation. Dev Cell. 2005 Oct; 9(4):444-6.
Score: 0.015
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Chen J, Roop DR. Mouse models in preclinical studies for pachyonychia congenita. J Investig Dermatol Symp Proc. 2005 Oct; 10(1):37-46.
Score: 0.015
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Koster MI, Roop DR. Genetic pathways required for epidermal morphogenesis. Eur J Cell Biol. 2004 Dec; 83(11-12):625-9.
Score: 0.014
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Koch PJ, Roop DR. The role of keratins in epidermal development and homeostasis--going beyond the obvious. J Invest Dermatol. 2004 Nov; 123(5):x-xi.
Score: 0.014
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Koster MI, Roop DR. p63 and epithelial appendage development. Differentiation. 2004 Oct; 72(8):364-70.
Score: 0.014
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Honeycutt KA, Koster MI, Roop DR. Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease. J Investig Dermatol Symp Proc. 2004 Sep; 9(3):261-8.
Score: 0.013
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Caulin C, Nguyen T, Longley MA, Zhou Z, Wang XJ, Roop DR. Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity. Cancer Res. 2004 Aug 01; 64(15):5054-8.
Score: 0.013
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Honeycutt KA, Roop DR. c-Myc and epidermal stem cell fate determination. J Dermatol. 2004 May; 31(5):368-75.
Score: 0.013
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Koster MI, Roop DR. Transgenic mouse models provide new insights into the role of p63 in epidermal development. Cell Cycle. 2004 Apr; 3(4):411-3.
Score: 0.013
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Koster MI, Roop DR. The role of p63 in development and differentiation of the epidermis. J Dermatol Sci. 2004 Feb; 34(1):3-9.
Score: 0.013
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Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev. 2004 Jan 15; 18(2):126-31.
Score: 0.013
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Arin MJ, Roop DR. Inducible mouse models for inherited skin diseases: implications for skin gene therapy. Cells Tissues Organs. 2004; 177(3):160-8.
Score: 0.013
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Koster MI, Huntzinger KA, Roop DR. Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation. J Investig Dermatol Symp Proc. 2002 Dec; 7(1):41-5.
Score: 0.012
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Zhou Z, Wang D, Wang XJ, Roop DR. In utero activation of K5.CrePR1 induces gene deletion. Genesis. 2002 Feb; 32(2):191-2.
Score: 0.011
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Arin MJ, Longley MA, Wang XJ, Roop DR. Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol. 2001 Feb 05; 152(3):645-9.
Score: 0.011
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Cao T, Longley MA, Wang XJ, Roop DR. An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol. 2001 Feb 05; 152(3):651-6.
Score: 0.011
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Ishitsuka Y, Roop DR, Ogawa T. "Structural imprinting" of the cutaneous immune effector function. Tissue Barriers. 2021 01 02; 9(1):1851561.
Score: 0.010
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Cao T, Wang XJ, Roop DR. Regulated cutaneous gene delivery: the skin as a bioreactor. Hum Gene Ther. 2000 Nov 01; 11(16):2297-300.
Score: 0.010
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Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft. Mol Cancer Res. 2021 02; 19(2):346-357.
Score: 0.010
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Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC, Roop DR. Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol. 2000 Oct 16; 151(2):389-400.
Score: 0.010
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Suga Y, Jarnik M, Attar PS, Longley MA, Bundman D, Steven AC, Koch PJ, Roop DR. Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, Vohwinkel syndrome and progressive symmetric erythrokeratoderma. J Cell Biol. 2000 Oct 16; 151(2):401-12.
Score: 0.010
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Wang XJ, Greenhalgh DA, Donehower LA, Roop DR. Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis. Mol Carcinog. 2000 Oct; 29(2):67-75.
Score: 0.010
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Liefer KM, Koster MI, Wang XJ, Yang A, McKeon F, Roop DR. Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res. 2000 Aug 01; 60(15):4016-20.
Score: 0.010
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Ogawa T, Ishitsuka Y, Nakamura Y, Kubota N, Saito A, Fujisawa Y, Watanabe R, Okiyama N, Suga Y, Roop DR, Fujimoto M. NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy. J Immunol. 2020 08 15; 205(4):907-914.
Score: 0.010
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Wojcik SM, Bundman DS, Roop DR. Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol. 2000 Jul; 20(14):5248-55.
Score: 0.010
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Wang XJ, Greenhalgh DA, Roop DR. Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation. Mol Carcinog. 2000 Mar; 27(3):200-9.
Score: 0.010
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Berton TR, Wang XJ, Zhou Z, Kellendonk C, Sch?tz G, Tsai S, Roop DR. Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis. 2000 Feb; 26(2):160-1.
Score: 0.010
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Wang XJ, Liefer KM, Greenhalgh DA, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation. Mol Carcinog. 1999 Dec; 26(4):305-11.
Score: 0.010
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Wojcik SM, Imakado S, Seki T, Longley MA, Petherbridge L, Bundman DS, Bickenbach JR, Rothnagel JA, Roop DR. Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle. Differentiation. 1999 Oct; 65(2):97-112.
Score: 0.010
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Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR. The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation. 1999 Oct; 65(2):119-30.
Score: 0.010
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Waikel RL, Wang XJ, Roop DR. Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene. 1999 Aug 26; 18(34):4870-8.
Score: 0.010
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Wang XJ, Liefer KM, Tsai S, O'Malley BW, Roop DR. Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8483-8.
Score: 0.009
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Barbulescu CC, Goldstein NB, Roop DR, Norris DA, Birlea SA. Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata. J Invest Dermatol. 2020 01; 140(1):29-37.
Score: 0.009
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DiSepio D, Bickenbach JR, Longley MA, Bundman DS, Rothnagel JA, Roop DR. Characterization of loricrin regulation in vitro and in transgenic mice. Differentiation. 1999 May; 64(4):225-35.
Score: 0.009
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Crumrine D, Khnykin D, Krieg P, Man MQ, Celli A, Mauro TM, Wakefield JS, Menon G, Mauldin E, Miner JH, Lin MH, Brash AR, Sprecher E, Radner FPW, Choate K, Roop D, Uchida Y, Gruber R, Schmuth M, Elias PM. Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte?Lipid Envelope. J Invest Dermatol. 2019 04; 139(4):760-768.
Score: 0.009
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Brinkley BR, Roop DR. Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function. Mol Carcinog. 1998 Nov; 23(3):185-92.
Score: 0.009
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45.
Score: 0.009
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Bonnekoh B, Greenhalgh DA, Chen SH, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model. J Invest Dermatol. 1998 Jun; 110(6):867-71.
Score: 0.009
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Bonnekoh B, Greenhalgh DA, Chen SH, Bickenbach J, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model. Adv Exp Med Biol. 1998; 451:335-43.
Score: 0.008
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Attar PS, Wertz PW, McArthur M, Imakado S, Bickenbach JR, Roop DR. Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function. Mol Endocrinol. 1997 Jun; 11(6):792-800.
Score: 0.008
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Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017 08 31; 36(35):4997-5005.
Score: 0.008
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Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2386-91.
Score: 0.008
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Bonnekoh B, Bickenbach JR, Roop DR. Immunological gene therapy approaches for malignant melanoma. 2. Preclinical studies and clinical strategies. Skin Pharmacol. 1997; 10(3):105-25.
Score: 0.008
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Birlea SA, Costin GE, Roop DR, Norris DA. Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization. Med Res Rev. 2017 07; 37(4):907-935.
Score: 0.008
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Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation. 1996 Dec; 61(2):129-39.
Score: 0.008
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Greenhalgh DA, Wang XJ, Donehower LA, Roop DR. Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha. Cancer Res. 1996 Oct 01; 56(19):4413-23.
Score: 0.008
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Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 01; 109(1).
Score: 0.008
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Greenhalgh DA, Wang XJ, Roop DR. Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox. J Investig Dermatol Symp Proc. 1996 Apr; 1(2):162-76.
Score: 0.008
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Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75. J Invest Dermatol. 2016 Jan; 136(1):45-51.
Score: 0.007
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Kumar V, Bouameur JE, B?r J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, L?ffler-Wirth H, Seibel P, Magin TM. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 07; 211(5):1057-75.
Score: 0.007
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Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R. MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015 Jul 23; 4.
Score: 0.007
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Greenhalgh DA, Wang XJ, Roop DR. Multistage skin carcinogenesis in transgenic mice. Proc Assoc Am Physicians. 1995 Jul; 107(2):258-75.
Score: 0.007
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DiSepio D, Jones A, Longley MA, Bundman D, Rothnagel JA, Roop DR. The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression. J Biol Chem. 1995 May 05; 270(18):10792-9.
Score: 0.007
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Rothnagel JA, Roop DR. Hair follicle companion layer: reacquainting an old friend. J Invest Dermatol. 1995 May; 104(5 Suppl):42S-43S.
Score: 0.007
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Greenhalgh DA, Wang XJ, Eckhardt JN, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy. Cell Growth Differ. 1995 May; 6(5):579-86.
Score: 0.007
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Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene. 2016 Jan 21; 35(3):290-300.
Score: 0.007
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Bonnekoh B, Greenhalgh DA, Bundman DS, Eckhardt JN, Longley MA, Chen SH, Woo SL, Roop DR. Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo. J Invest Dermatol. 1995 Mar; 104(3):313-7.
Score: 0.007
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Bickenbach JR, Greer JM, Bundman DS, Rothnagel JA, Roop DR. Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. J Invest Dermatol. 1995 Mar; 104(3):405-10.
Score: 0.007
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Roop D. Defects in the barrier. Science. 1995 Jan 27; 267(5197):474-5.
Score: 0.007
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Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene. 1995 Jan 19; 10(2):279-89.
Score: 0.007
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Greenhalgh DA, Rothnagel JA, Roop DR. Epidermis: an attractive target tissue for gene therapy. J Invest Dermatol. 1994 Nov; 103(5 Suppl):63S-69S.
Score: 0.007
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Rothnagel JA, Longley MA, Bundman DS, Naylor SL, Lalley PA, Jenkins NA, Gilbert DJ, Copeland NG, Roop DR. Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3. Genomics. 1994 Sep 15; 23(2):450-6.
Score: 0.007
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Rorke EA, Adhikary G, Young CA, Roop DR, Eckert RL. Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype. J Invest Dermatol. 2015 Jan; 135(1):170-180.
Score: 0.007
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Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR. Genetic disorders of keratin: are scarring alopecias a sub-set? J Dermatol Sci. 1994 Jul; 7 Suppl:S164-9.
Score: 0.007
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Greenhalgh DA, Wang XJ, Rothnagel JA, Eckhardt JN, Quintanilla MI, Barber JL, Bundman DS, Longley MA, Schlegel R, Roop DR. Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas. Cell Growth Differ. 1994 Jun; 5(6):667-75.
Score: 0.007
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Wang XJ, Greenhalgh DA, Eckhardt JN, Rothnagel JA, Roop DR. Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol Carcinog. 1994 May; 10(1):15-22.
Score: 0.007
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van Steensel MAM, Coulombe PA, Kaspar RL, Milstone LM, McLean IWH, Roop DR, Smith FJD, Sprecher E, Schwartz ME. Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting. J Invest Dermatol. 2014 Mar; 134(3):588-591.
Score: 0.006
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Sch?fer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med. 2014 04; 6(4):442-57.
Score: 0.006
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Greenhalgh DA, Wang XJ, Dominey AM, Rothnagel JA, Roop DR. Development of transgenic mouse models of skin carcinogenesis: potential applications. Prog Clin Biol Res. 1994; 387:75-94.
Score: 0.006
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Greenhalgh DA, Roop DR. Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting. Adv Cancer Res. 1994; 64:247-96.
Score: 0.006
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Greenhalgh DA, Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop DR. Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res. 1993 Nov 01; 53(21):5071-5.
Score: 0.006
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Rothnagel JA, Greenhalgh DA, Wang XJ, Sellheyer K, Bickenbach JR, Dominey AM, Roop DR. Transgenic models of skin diseases. Arch Dermatol. 1993 Nov; 129(11):1430-6.
Score: 0.006
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Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR. Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene. J Invest Dermatol. 1993 Oct; 101(4):506-13.
Score: 0.006
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Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C. Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci. 2013 Sep 26; 14(10):19540-55.
Score: 0.006
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White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 2013 Oct; 123(10):4390-404.
Score: 0.006
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Greenhalgh DA, Rothnagel JA, Wang XJ, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C, Roop DR. Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia. Oncogene. 1993 Aug; 8(8):2145-57.
Score: 0.006
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Hohl D, Ruf Olano B, de Viragh PA, Huber M, Detrisac CJ, Schnyder UW, Roop DR. Expression patterns of loricrin in various species and tissues. Differentiation. 1993 Aug; 54(1):25-34.
Score: 0.006
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Sellheyer K, Bickenbach JR, Rothnagel JA, Bundman D, Longley MA, Krieg T, Roche NS, Roberts AB, Roop DR. Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5237-41.
Score: 0.006
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Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ. Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis. Cell Death Differ. 2013 Aug; 20(8):1080-8.
Score: 0.006
-
Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Roop DR. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog. 1993; 7(2):99-110.
Score: 0.006
-
Yasuda M, Claypool DJ, Guevara E, Roop DR, Chen J. Genetic manipulation of keratinocyte stem cells with lentiviral vectors. Methods Mol Biol. 2013; 989:143-51.
Score: 0.006
-
Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA. A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012; 7(11):e50634.
Score: 0.006
-
Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells. 2012 Oct; 30(10):2100-13.
Score: 0.006
-
Luo Y, Ellis LZ, Dallaglio K, Takeda M, Robinson WA, Robinson SE, Liu W, Lewis KD, McCarter MD, Gonzalez R, Norris DA, Roop DR, Spritz RA, Ahn NG, Fujita M. Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance. J Invest Dermatol. 2012 Oct; 132(10):2440-2450.
Score: 0.006
-
Sch?fer M, Farwanah H, Willrodt AH, Huebner AJ, Sandhoff K, Roop D, Hohl D, Bloch W, Werner S. Nrf2 links epidermal barrier function with antioxidant defense. EMBO Mol Med. 2012 May; 4(5):364-79.
Score: 0.006
-
Acin S, Li Z, Mejia O, Roop DR, El-Naggar AK, Caulin C. Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras. J Pathol. 2011 Dec; 225(4):479-89.
Score: 0.005
-
Terzian T, Dumble M, Arbab F, Thaller C, Donehower LA, Lozano G, Justice MJ, Roop DR, Box NF. Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug; 224(4):540-52.
Score: 0.005
-
Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409.
Score: 0.005
-
Rosenthal DS, Steinert PM, Chung S, Huff CA, Johnson J, Yuspa SH, Roop DR. A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Growth Differ. 1991 Feb; 2(2):107-13.
Score: 0.005
-
Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC, Chow KS, Klemm DJ, Roop DR, Majka SM. Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Stem Cells. 2011 Feb; 29(2):206-16.
Score: 0.005
-
Franco HL, Dai D, Lee KY, Rubel CA, Roop D, Boerboom D, Jeong JW, Lydon JP, Bagchi IC, Bagchi MK, DeMayo FJ. WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J. 2011 Apr; 25(4):1176-87.
Score: 0.005
-
Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF. p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res. 2010 Dec; 23(6):781-94.
Score: 0.005
-
Rothnagel JA, Longley MA, Bundman D, Greenhalgh DA, Dominey AM, Roop DR. Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders. J Invest Dermatol. 1990 Nov; 95(5 Suppl):59S-61S.
Score: 0.005
-
Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J. Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb; 131(2):302-10.
Score: 0.005
-
Smith GH, Mehrel T, Roop DR. Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ. 1990 Apr; 1(4):161-70.
Score: 0.005
-
Li F, Huang Q, Chen J, Peng Y, Roop DR, Bedford JS, Li CY. Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci Signal. 2010 Feb 23; 3(110):ra13.
Score: 0.005
-
De Luca LM, Huang FL, Roop DR. Retinoids and control of epithelial differentiation and keratin biosynthesis in hamster trachea. Methods Enzymol. 1990; 190:91-100.
Score: 0.005
-
Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI. Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ. 2010 Jan; 17(1):180-3; author reply 184-6.
Score: 0.005
-
Kim S, Choi IF, Quante JR, Zhang L, Roop DR, Koster MI. p63 directly induces expression of Alox12, a regulator of epidermal barrier formation. Exp Dermatol. 2009 Dec; 18(12):1016-21.
Score: 0.005
-
Chen D, Lin Q, Box N, Roop D, Ishii S, Matsuzaki K, Fan T, Hornyak TJ, Reed JA, Stavnezer E, Timchenko NA, Medrano EE. SKI knockdown inhibits human melanoma tumor growth in vivo. Pigment Cell Melanoma Res. 2009 Dec; 22(6):761-72.
Score: 0.005
-
Yuspa SH, Kilkenny AE, Steinert PM, Roop DR. Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol. 1989 Sep; 109(3):1207-17.
Score: 0.005
-
Fete M, vanBokhoven H, Clements SE, McKeon F, Roop DR, Koster MI, Missero C, Attardi LD, Lombillo VA, Ratovitski E, Julapalli M, Ruths D, Sybert VP, Siegfried EC, Bree AF. International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1885-93.
Score: 0.005
-
Refaeli Y, Bhoumik A, Roop DR, Ronai ZA. Melanoma-initiating cells: a compass needed. EMBO Rep. 2009 Sep; 10(9):965-72.
Score: 0.005
-
Roop DR, Mehrel T, Krieg TM, Nakazawa H, Cheng CK, Yuspa SH. Keratin expression in mouse epidermal tumors. Carcinog Compr Surv. 1989; 11:257-71.
Score: 0.005
-
Roop DR, Krieg TM, Mehrel T, Cheng CK, Yuspa SH. Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res. 1988 Jun 01; 48(11):3245-52.
Score: 0.004
-
Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. J Dermatol Sci. 2008 Sep; 51(3):151-7.
Score: 0.004
-
Iwai N, Zhou Z, Roop DR, Behringer RR. Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium. Stem Cells. 2008 May; 26(5):1298-306.
Score: 0.004
-
Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA. Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 01; 317(1):187-95.
Score: 0.004
-
Yuspa SH, Kilkenny A, Roop DR. Aberrant differentiation in mouse skin carcinogenesis. IARC Sci Publ. 1988; (92):3-10.
Score: 0.004
-
Yuspa SH, Hennings H, Tucker RW, Jaken S, Kilkenny AE, Roop DR. Signal transduction for proliferation and differentiation in keratinocytes. Ann N Y Acad Sci. 1988; 548:191-6.
Score: 0.004
-
Steinert PM, Roop DR. Molecular and cellular biology of intermediate filaments. Annu Rev Biochem. 1988; 57:593-625.
Score: 0.004
-
Lee S, Chari NS, Kim HW, Wang X, Roop DR, Cho SH, DiGiovanni J, McDonnell TJ. Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis. Mol Carcinog. 2007 Dec; 46(12):949-57.
Score: 0.004
-
Fisher C, Jones A, Roop DR. Abnormal expression and processing of keratins in pupoid fetus (pf/pf) and repeated epilation (Er/Er) mutant mice. J Cell Biol. 1987 Oct; 105(4):1807-19.
Score: 0.004
-
Shah VR, Koster MI, Roop DR, Spencer DM, Wei L, Li Q, Schwartz RJ, Chang J. Double-inducible gene activation system for caspase 3 and 9 in epidermis. Genesis. 2007 Apr; 45(4):194-9.
Score: 0.004
-
Roop DR. Regulation of keratin gene expression during differentiation of epidermal and vaginal epithelial cells. Curr Top Dev Biol. 1987; 22:195-207.
Score: 0.004
-
Roop DR, Huitfeldt H, Kilkenny A, Yuspa SH. Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins. Differentiation. 1987; 35(2):143-50.
Score: 0.004
-
Chen J, Cheng X, Merched-Sauvage M, Caulin C, Roop DR, Koch PJ. An unexpected role for keratin 10 end domains in susceptibility to skin cancer. J Cell Sci. 2006 Dec 15; 119(Pt 24):5067-76.
Score: 0.004
-
Geng S, Mezentsev A, Kalachikov S, Raith K, Roop DR, Panteleyev AA. Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function. J Cell Sci. 2006 Dec 01; 119(Pt 23):4901-12.
Score: 0.004
-
Roop DR, Lowy DR, Tambourin PE, Strickland J, Harper JR, Balaschak M, Spangler EF, Yuspa SH. An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature. 1986 Oct 30-Nov 5; 323(6091):822-4.
Score: 0.004
-
Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 01; 299(1):122-36.
Score: 0.004
-
Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM. Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29.
Score: 0.004
-
Keyes WM, Vogel H, Koster MI, Guo X, Qi Y, Petherbridge KM, Roop DR, Bradley A, Mills AA. p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8435-40.
Score: 0.004
-
Nguyen BC, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, Koster MI, Zhang Z, Wang J, Tommasi di Vignano A, Kitajewski J, Chiorino G, Roop DR, Missero C, Dotto GP. Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev. 2006 Apr 15; 20(8):1028-42.
Score: 0.004
-
Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 06; 25(29):4027-32.
Score: 0.004
-
Toftgard R, Yuspa SH, Roop DR. Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1985 Nov; 45(11 Pt 2):5845-50.
Score: 0.004
-
Steinert PM, Steven AC, Roop DR. The molecular biology of intermediate filaments. Cell. 1985 Sep; 42(2):411-20.
Score: 0.004
-
Steinert PM, Parry DA, Idler WW, Johnson LD, Steven AC, Roop DR. Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits. J Biol Chem. 1985 Jun 10; 260(11):7142-9.
Score: 0.004
-
Krieg TM, Schafer MP, Cheng CK, Filpula D, Flaherty P, Steinert PM, Roop DR. Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem. 1985 May 25; 260(10):5867-70.
Score: 0.004
-
Mammucari C, Tommasi di Vignano A, Sharov AA, Neilson J, Havrda MC, Roop DR, Botchkarev VA, Crabtree GR, Dotto GP. Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell. 2005 May; 8(5):665-76.
Score: 0.004
-
Roop DR, Cheng CK, Toftgard R, Stanley JR, Steinert PM, Yuspa SH. The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression. Ann N Y Acad Sci. 1985; 455:426-35.
Score: 0.003
-
Steinert PM, Idler WW, Zhou XM, Johnson LD, Parry DA, Steven AC, Roop DR. Structural and functional implications of amino acid sequences of keratin intermediate filament subunits. Ann N Y Acad Sci. 1985; 455:451-61.
Score: 0.003
-
Xu X, Kawachi Y, Nakamura Y, Sakurai H, Hirota A, Banno T, Takahashi T, Roop DR, Otsuka F. Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes. J Invest Dermatol. 2004 Dec; 123(6):1120-6.
Score: 0.003
-
Steinert PM, Parry DA, Racoosin EL, Idler WW, Steven AC, Trus BL, Roop DR. The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins. Proc Natl Acad Sci U S A. 1984 Sep; 81(18):5709-13.
Score: 0.003
-
Matsumoto T, Kiguchi K, Jiang J, Carbajal S, Ruffino L, Beltr?n L, Wang XJ, Roop DR, DiGiovanni J. Development of transgenic mice that inducibly express an active form of c-Src in the epidermis. Mol Carcinog. 2004 Aug; 40(4):189-200.
Score: 0.003
-
Roop DR, Cheng CK, Titterington L, Meyers CA, Stanley JR, Steinert PM, Yuspa SH. Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem. 1984 Jul 10; 259(13):8037-40.
Score: 0.003
-
Sil AK, Maeda S, Sano Y, Roop DR, Karin M. IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature. 2004 Apr 08; 428(6983):660-4.
Score: 0.003
-
Bigelow RL, Chari NS, Unden AB, Spurgers KB, Lee S, Roop DR, Toftgard R, McDonnell TJ. Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1. J Biol Chem. 2004 Jan 09; 279(2):1197-205.
Score: 0.003
-
Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H, Noda S, Takahashi S, Imakado S, Kotsuji T, Otsuka F, Roop DR, Harada T, Engel JD, Yamamoto M. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet. 2003 Nov; 35(3):238-45.
Score: 0.003
-
Roop DR, Hawley-Nelson P, Cheng CK, Yuspa SH. Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture. J Invest Dermatol. 1983 Jul; 81(1 Suppl):144s-9s.
Score: 0.003
-
Steinert PM, Steven AC, Roop DR. Structural features of epidermal keratin filaments reassembled in vitro. J Invest Dermatol. 1983 Jul; 81(1 Suppl):86s-90s.
Score: 0.003
-
Roop DR, Hawley-Nelson P, Cheng CK, Yuspa SH. Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A. 1983 Feb; 80(3):716-20.
Score: 0.003
-
Cao T, He W, Roop DR, Wang XJ. K14-GLp65 transactivator induces transgene expression in embryonic epidermis. Genesis. 2002 Feb; 32(2):189-90.
Score: 0.003
-
Jarnik M, de Viragh PA, Sch?rer E, Bundman D, Simon MN, Roop DR, Steven AC. Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system. J Invest Dermatol. 2002 Jan; 118(1):102-9.
Score: 0.003
-
Roop DR, Kristo P, Stumph WE, Tsai MJ, O'Malley BW. Structure and expression of a chicken gene coding for U1 RNA. Cell. 1981 Mar; 23(3):671-80.
Score: 0.003
-
Roop DR, Tsai SY, Tsai MJ, O'Malley BW. Definition of the transcription unit of the natural ovalbumin gene. Prog Clin Biol Res. 1981; 66 Pt B:381-92.
Score: 0.003
-
Long DJ, Waikel RL, Wang XJ, Perlaky L, Roop DR, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res. 2000 Nov 01; 60(21):5913-5.
Score: 0.003
-
Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 1999 Apr 22; 398(6729):708-13.
Score: 0.002
-
Roop DR, Nordstrom JL, Tsai SY, Tsai MJ, O'Malley BW. Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell. 1978 Oct; 15(2):671-85.
Score: 0.002
-
Klug DB, Carter C, Crouch E, Roop D, Conti CJ, Richie ER. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11822-7.
Score: 0.002
-
Roop DR, Riggsby WS. Choice of labeled precursors in synthesis of DNA for molecular hybridization. Biochem Biophys Res Commun. 1978 Apr 14; 81(3):764-71.
Score: 0.002
-
Rodr?guez-Villanueva J, Greenhalgh D, Wang XJ, Bundman D, Cho S, Delehedde M, Roop D, McDonnell TJ. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene. 1998 Feb 19; 16(7):853-63.
Score: 0.002
-
Borkowski TA, Letterio JJ, Mackall CL, Saitoh A, Wang XJ, Roop DR, Gress RE, Udey MC. A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest. 1997 Aug 01; 100(3):575-81.
Score: 0.002
-
Borkowski TA, Letterio JJ, Mackall CL, Saitoh A, Farr AG, Wang XJ, Roop DR, Gress RE, Udey MC. Langerhans cells in the TGF beta 1 null mouse. Adv Exp Med Biol. 1997; 417:307-10.
Score: 0.002
-
Ishida-Yamamoto A, Eady RA, Watt FM, Roop DR, Hohl D, Iizuka H. Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem. 1996 Feb; 44(2):167-75.
Score: 0.002
-
Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A. Functional analysis of activins during mammalian development. Nature. 1995 Mar 23; 374(6520):354-6.
Score: 0.002
-
Matzuk MM, Lu N, Vogel H, Sellheyer K, Roop DR, Bradley A. Multiple defects and perinatal death in mice deficient in follistatin. Nature. 1995 Mar 23; 374(6520):360-3.
Score: 0.002
-
Kulesz-Martin MF, Lisafeld B, Paterson J, Driscoll D, Shudo K, Roop DR, Kisiel ND. Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model. Cancer Detect Prev. 1995; 19(4):355-66.
Score: 0.002
-
Heyden A, L?tzow-Holm C, Clausen OP, Thrane EV, Brandtzaeg P, Roop DR, Yuspa SH, Huitfeldt HS. Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution. Differentiation. 1994 Sep; 57(3):187-93.
Score: 0.002
-
Gimenez-Conti IB, Lynch M, Roop D, Bhowmik S, Majeski P, Conti CJ. Expression of keratins in mouse vaginal epithelium. Differentiation. 1994 May; 56(3):143-51.
Score: 0.002
-
Sundberg JP, Dunstan RW, Roop DR, Beamer WG. Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype. J Invest Dermatol. 1994 May; 102(5):781-8.
Score: 0.002
-
Sundberg JP, Erickson AA, Roop DR, Binder RL. Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10. Cancer Res. 1994 Mar 01; 54(5):1344-51.
Score: 0.002
-
Kartasova T, Roop DR, Holbrook KA, Yuspa SH. Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network. J Cell Biol. 1993 Mar; 120(5):1251-61.
Score: 0.002
-
Robles AI, Gimenez-Conti IB, Roop D, Slaga TJ, Conti CJ. Low frequency of codon 61 Ha-ras mutations and lack of keratin 13 expression in 7,12-dimethylbenz[a]-anthracene-induced hamster skin tumors. Mol Carcinog. 1993; 7(2):94-8.
Score: 0.001
-
Blouin R, Blouin MJ, Royal I, Grenier A, Roop DR, Loranger A, Marceau N. Cytokeratin 14 expression in rat liver cells in culture and localization in vivo. Differentiation. 1992 Dec; 52(1):45-54.
Score: 0.001
-
Kartasova T, Roop DR, Yuspa SH. Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors. Mol Carcinog. 1992; 6(1):18-25.
Score: 0.001
-
Sundberg JP, Roop DR, Dunstan R, Lavker R, Sun TT. Interaction between dermal papilla and bulge: the rhino mouse mutation as a model system. Ann N Y Acad Sci. 1991 Dec 26; 642:496-9.
Score: 0.001
-
Huitfeldt HS, Heyden A, Clausen OP, Thrane EV, Roop D, Yuspa SH. Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors. Carcinogenesis. 1991 Nov; 12(11):2063-7.
Score: 0.001
-
Sundberg JP, Hanson CA, Roop DR, Brown KS, Bedigian HG. Myoepitheliomas in inbred laboratory mice. Vet Pathol. 1991 Jul; 28(4):313-23.
Score: 0.001
-
Yuspa SH, Kilkenny A, Cheng C, Roop D, Hennings H, Kruszewski F, Lee E, Strickland J, Greenhalgh DA. Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis. Environ Health Perspect. 1991 Jun; 93:3-10.
Score: 0.001
-
Gimenez-Conti I, Aldaz CM, Bianchi AB, Roop DR, Slaga TJ, Conti CJ. Early expression of type I K13 keratin in the progression of mouse skin papillomas. Carcinogenesis. 1990 Nov; 11(11):1995-9.
Score: 0.001
-
Yuspa SH, Hennings H, Roop D, Strickland J, Greenhalgh DA. The malignant conversion step of mouse skin carcinogenesis. Environ Health Perspect. 1990 Aug; 88:193-5.
Score: 0.001
-
Gimenez-Conti IB, Shin DM, Bianchi AB, Roop DR, Hong WK, Conti CJ, Slaga TJ. Changes in keratin expression during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis. Cancer Res. 1990 Jul 15; 50(14):4441-5.
Score: 0.001
-
Steven AC, Bisher ME, Roop DR, Steinert PM. Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes. J Struct Biol. 1990 Jul-Sep; 104(1-3):150-62.
Score: 0.001
-
Cheng C, Kilkenny AE, Roop D, Yuspa SH. The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes. Mol Carcinog. 1990; 3(6):363-73.
Score: 0.001
-
Yuspa SH, Kilkenny AE, Roop DR, Strickland JE, Tucker R, Hennings H, Jaken S. Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: altered differentiation and growth, mutations, and transformation. Prog Clin Biol Res. 1989; 298:127-35.
Score: 0.001
-
Zhou XM, Idler WW, Steven AC, Roop DR, Steinert PM. The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences. J Biol Chem. 1988 Oct 25; 263(30):15584-9.
Score: 0.001
-
Rogers GE, Martinet N, Steinert P, Wynn P, Roop D, Kilkenny A, Morgan D, Yuspa SH. A procedure for the culture of hair follicles as functionally intact organoids. Clin Dermatol. 1988 Oct-Dec; 6(4):36-41.
Score: 0.001
-
Aldaz CM, Conti CJ, Larcher F, Trono D, Roop DR, Chesner J, Whitehead T, Slaga TJ. Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas. Cancer Res. 1988 Jun 01; 48(11):3253-7.
Score: 0.001
-
Ansel JC, Luger TA, Lowry D, Perry P, Roop DR, Mountz JD. The expression and modulation of IL-1 alpha in murine keratinocytes. J Immunol. 1988 Apr 01; 140(7):2274-8.
Score: 0.001
-
Hawley-Nelson P, Roop DR, Cheng CK, Krieg TM, Yuspa SH. Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis. Mol Carcinog. 1988; 1(3):202-11.
Score: 0.001
-
Nischt R, Roop DR, Mehrel T, Yuspa SH, Rentrop M, Winter H, Schweizer J. Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia. Mol Carcinog. 1988; 1(2):96-108.
Score: 0.001
-
Rothnagel JA, Mehrel T, Idler WW, Roop DR, Steinert PM. The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit. J Biol Chem. 1987 Nov 15; 262(32):15643-8.
Score: 0.001
-
Rogers G, Martinet N, Steinert P, Wynn P, Roop D, Kilkenny A, Morgan D, Yuspa SH. Cultivation of murine hair follicles as organoids in a collagen matrix. J Invest Dermatol. 1987 Oct; 89(4):369-79.
Score: 0.001
-
Meruelo D, Rossomando A, Scandalis S, D'Eustachio P, Fournier RE, Roop DR, Saxe D, Blatt C, Nesbitt MN. Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15. Immunogenetics. 1987; 25(6):361-72.
Score: 0.001
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Hawley-Nelson P, Roop DR, Cheng CK, Yuspa SH. Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures. J Invest Dermatol. 1986 Oct; 87(4):454-9.
Score: 0.001
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Harper JR, Roop DR, Yuspa SH. Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression. Mol Cell Biol. 1986 Sep; 6(9):3144-9.
Score: 0.001
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Huang FL, Roop DR, De Luca LM. Vitamin A deficiency and keratin biosynthesis in cultured hamster trachea. In Vitro Cell Dev Biol. 1986 Apr; 22(4):223-30.
Score: 0.001
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Toftgard R, Roop DR, Yuspa SH. Proto-oncogene expression during two-stage carcinogenesis in mouse skin. Carcinogenesis. 1985 Apr; 6(4):655-7.
Score: 0.001
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De Luca LM, Roop D, Huang FL. Vitamin A: a key nutrient for the maintenance of epithelial differentiation. Acta Vitaminol Enzymol. 1985; 7 Suppl:13-20.
Score: 0.001
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Steinert PM, Rice RH, Roop DR, Trus BL, Steven AC. Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature. 1983 Apr 28; 302(5911):794-800.
Score: 0.001
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Lai EC, Roop DR, Tsai MJ, Woo SL, O'Malley BW. Heterogeneous initiation regions for transcription of the chicken ovomucoid gene. Nucleic Acids Res. 1982 Sep 25; 10(18):5553-67.
Score: 0.001
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Tsai SY, Roop DR, Stumph WE, Tsai MJ, O'Malley BW. Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed. Biochemistry. 1980 Apr 29; 19(9):1755-61.
Score: 0.001
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Nordstrom JL, Roop DR, Tsai MJ, O'Malley BW. Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei. Nature. 1979 Mar 22; 278(5702):328-31.
Score: 0.001
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O'Malley BW, Roop DR, Lai EC, Nordstrom JL, Catterall JF, Swaneck GE, Colbert DA, Tsai MJ, Dugaiczyk A, Woo SL. The ovalbumin gene: organization, structure, transcription, and regulation. Recent Prog Horm Res. 1979; 35:1-46.
Score: 0.001
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Swaneck GE, Tsai SY, Tsai MJ, Nordstrom JL, Roop DR, O'Malley BW. The ovalbumin gene: transcriptional regulation by estrogen. Adv Exp Med Biol. 1979; 117:461-85.
Score: 0.001
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Tsai SY, Roop DR, Tsai MJ, Stein JP, Means AR, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. Biochemistry. 1978 Dec 26; 17(26):5773-80.
Score: 0.001
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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