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Connection

Dennis Roop to Disease Models, Animal

This is a "connection" page, showing publications Dennis Roop has written about Disease Models, Animal.

 
Connection Strength
 
 
 
0.927
 
  1. Koster MI, Marinari B, Payne AS, Kantaputra PN, Costanzo A, Roop DR. DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1942-7.
    View in: PubMed
    Score: 0.172
  2. Cao T, Longley MA, Wang XJ, Roop DR. An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol. 2001 Feb 05; 152(3):651-6.
    View in: PubMed
    Score: 0.095
  3. Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR. Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS One. 2016; 11(8):e0161465.
    View in: PubMed
    Score: 0.070
  4. Torchia EC, Caulin C, Acin S, Terzian T, Kubick BJ, Box NF, Roop DR. Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma. Oncogene. 2012 May 24; 31(21):2680-90.
    View in: PubMed
    Score: 0.050
  5. Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409.
    View in: PubMed
    Score: 0.048
  6. Rothnagel JA, Longley MA, Bundman D, Greenhalgh DA, Dominey AM, Roop DR. Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders. J Invest Dermatol. 1990 Nov; 95(5 Suppl):59S-61S.
    View in: PubMed
    Score: 0.047
  7. Chen J, Roop DR. Genetically engineered mouse models for skin research: taking the next step. J Dermatol Sci. 2008 Oct; 52(1):1-12.
    View in: PubMed
    Score: 0.039
  8. Chen J, Jaeger K, Den Z, Koch PJ, Sundberg JP, Roop DR. Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita. J Invest Dermatol. 2008 Feb; 128(2):270-9.
    View in: PubMed
    Score: 0.038
  9. Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest. 2007 Jul; 117(7):1893-901.
    View in: PubMed
    Score: 0.037
  10. Chen J, Roop DR. Mouse models in preclinical studies for pachyonychia congenita. J Investig Dermatol Symp Proc. 2005 Oct; 10(1):37-46.
    View in: PubMed
    Score: 0.033
  11. Arin MJ, Roop DR. Inducible mouse models for inherited skin diseases: implications for skin gene therapy. Cells Tissues Organs. 2004; 177(3):160-8.
    View in: PubMed
    Score: 0.029
  12. Arin MJ, Longley MA, Wang XJ, Roop DR. Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol. 2001 Feb 05; 152(3):645-9.
    View in: PubMed
    Score: 0.024
  13. Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft. Mol Cancer Res. 2021 02; 19(2):346-357.
    View in: PubMed
    Score: 0.023
  14. Bonnekoh B, Greenhalgh DA, Chen SH, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model. J Invest Dermatol. 1998 Jun; 110(6):867-71.
    View in: PubMed
    Score: 0.020
  15. Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017 08 31; 36(35):4997-5005.
    View in: PubMed
    Score: 0.018
  16. Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation. 1996 Dec; 61(2):129-39.
    View in: PubMed
    Score: 0.018
  17. Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J. Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75. J Invest Dermatol. 2016 Jan; 136(1):45-51.
    View in: PubMed
    Score: 0.017
  18. Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R. MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015 Jul 23; 4.
    View in: PubMed
    Score: 0.016
  19. Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene. 2016 Jan 21; 35(3):290-300.
    View in: PubMed
    Score: 0.016
  20. Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR. Genetic disorders of keratin: are scarring alopecias a sub-set? J Dermatol Sci. 1994 Jul; 7 Suppl:S164-9.
    View in: PubMed
    Score: 0.015
  21. Sch?fer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med. 2014 04; 6(4):442-57.
    View in: PubMed
    Score: 0.015
  22. Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Roop DR. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog. 1993; 7(2):99-110.
    View in: PubMed
    Score: 0.014
  23. Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA. A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012; 7(11):e50634.
    View in: PubMed
    Score: 0.013
  24. Acin S, Li Z, Mejia O, Roop DR, El-Naggar AK, Caulin C. Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras. J Pathol. 2011 Dec; 225(4):479-89.
    View in: PubMed
    Score: 0.012
  25. Terzian T, Dumble M, Arbab F, Thaller C, Donehower LA, Lozano G, Justice MJ, Roop DR, Box NF. Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug; 224(4):540-52.
    View in: PubMed
    Score: 0.012
  26. Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF. p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res. 2010 Dec; 23(6):781-94.
    View in: PubMed
    Score: 0.012
  27. Refaeli Y, Bhoumik A, Roop DR, Ronai ZA. Melanoma-initiating cells: a compass needed. EMBO Rep. 2009 Sep; 10(9):965-72.
    View in: PubMed
    Score: 0.011
  28. Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. J Dermatol Sci. 2008 Sep; 51(3):151-7.
    View in: PubMed
    Score: 0.010
  29. Kulesz-Martin MF, Lisafeld B, Paterson J, Driscoll D, Shudo K, Roop DR, Kisiel ND. Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model. Cancer Detect Prev. 1995; 19(4):355-66.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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