 Connection
Dennis Roop to Humans
This is a "connection" page, showing publications Dennis Roop has written about Humans.
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Warshauer EM, Brown A, Fuentes I, Shortt J, Gignoux C, Montinaro F, Metspalu M, Youssefian L, Vahidnezhad H, Jack?w J, Christiano AM, Uitto J, Fajardo-Ram?rez ?R, Salas-Alanis JC, McGrath JA, Consuegra L, Rivera C, Maier PA, Runfeldt G, Behar DM, Skorecki K, Sprecher E, Palisson F, Norris DA, Bruckner AL, Kogut I, Bilousova G, Roop DR. Ancestral patterns of recessive dystrophic epidermolysis bullosa mutations in Hispanic populations suggest sephardic ancestry. Am J Med Genet A. 2021 11; 185(11):3390-3400.
Score: 0.021
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Ishitsuka Y, Roop DR. Loricrin: Past, Present, and Future. Int J Mol Sci. 2020 Mar 25; 21(7).
Score: 0.019
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Ishitsuka Y, Roop DR. Loricrin Confers Photoprotective Function against?UVB in Corneocytes. J Invest Dermatol. 2018 12; 138(12):2684-2687.
Score: 0.017
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Bilousova G, Roop DR. Induced pluripotent stem cells in dermatology: potentials, advances, and limitations. Cold Spring Harb Perspect Med. 2014 Nov 03; 4(11):a015164.
Score: 0.013
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Chen J, Roop DR. Mimicking hair disorders by genetic manipulation of organ-cultured human hair follicles. J Invest Dermatol. 2012 Oct; 132(10):2312-2314.
Score: 0.011
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Kubick BJ, Roop DR. A fitness model for melanoma-initiating cells. Pigment Cell Melanoma Res. 2011 Jun; 24(3):396-7.
Score: 0.010
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Box NF, Torchia EC, Roop DR. Are stem cell niches shared for skin cancers? Pigment Cell Melanoma Res. 2010 Aug; 23(4):517-20.
Score: 0.010
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Torchia EC, Chen Y, Sheng H, Katayama H, Fitzpatrick J, Brinkley WR, Caulin C, Sen S, Roop DR. A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors. Cancer Res. 2009 Sep 15; 69(18):7207-15.
Score: 0.009
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Koster MI, Marinari B, Payne AS, Kantaputra PN, Costanzo A, Roop DR. DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1942-7.
Score: 0.009
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Roop D, Toftg?rd R. Hedgehog in Wnterland. Nat Genet. 2008 Sep; 40(9):1040-1.
Score: 0.009
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Koster MI, Roop DR. Sorting out the p63 signaling network. J Invest Dermatol. 2008 Jul; 128(7):1617-9.
Score: 0.009
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Koster MI, Dai D, Roop DR. Conflicting roles for p63 in skin development and carcinogenesis. Cell Cycle. 2007 Feb 01; 6(3):269-73.
Score: 0.008
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Buitrago W, Roop DR. Oct-4: the almighty POUripotent regulator? J Invest Dermatol. 2007 Feb; 127(2):260-2.
Score: 0.008
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Koster MI, Roop DR. Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol. 2007; 23:93-113.
Score: 0.008
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Koster MI, Lu SL, White LD, Wang XJ, Roop DR. Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression. Cancer Res. 2006 Apr 15; 66(8):3981-6.
Score: 0.007
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Koster MI, Kim S, Huang J, Williams T, Roop DR. TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol. 2006 Jan 01; 289(1):253-61.
Score: 0.007
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Koster MI, Roop DR. Asymmetric cell division in skin development: a new look at an old observation. Dev Cell. 2005 Oct; 9(4):444-6.
Score: 0.007
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Chen J, Roop DR. Mouse models in preclinical studies for pachyonychia congenita. J Investig Dermatol Symp Proc. 2005 Oct; 10(1):37-46.
Score: 0.007
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Koster MI, Roop DR. Genetic pathways required for epidermal morphogenesis. Eur J Cell Biol. 2004 Dec; 83(11-12):625-9.
Score: 0.007
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Koch PJ, Roop DR. The role of keratins in epidermal development and homeostasis--going beyond the obvious. J Invest Dermatol. 2004 Nov; 123(5):x-xi.
Score: 0.007
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Koster MI, Roop DR. p63 and epithelial appendage development. Differentiation. 2004 Oct; 72(8):364-70.
Score: 0.007
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Honeycutt KA, Koster MI, Roop DR. Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease. J Investig Dermatol Symp Proc. 2004 Sep; 9(3):261-8.
Score: 0.007
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Koster MI, Roop DR. The role of p63 in development and differentiation of the epidermis. J Dermatol Sci. 2004 Feb; 34(1):3-9.
Score: 0.006
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Arin MJ, Roop DR. Inducible mouse models for inherited skin diseases: implications for skin gene therapy. Cells Tissues Organs. 2004; 177(3):160-8.
Score: 0.006
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Ogawa T, Ishitsuka Y, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M, Roop DR, Nomura T. Loricrin Protects against Chemical Carcinogenesis. J Invest Dermatol. 2022 07; 142(7):2023-2026.e1.
Score: 0.005
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Arin MJ, Longley MA, Wang XJ, Roop DR. Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders. J Cell Biol. 2001 Feb 05; 152(3):645-9.
Score: 0.005
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Cao T, Longley MA, Wang XJ, Roop DR. An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol. 2001 Feb 05; 152(3):651-6.
Score: 0.005
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Ishitsuka Y, Roop DR, Ogawa T. "Structural imprinting" of the cutaneous immune effector function. Tissue Barriers. 2021 01 02; 9(1):1851561.
Score: 0.005
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Cao T, Wang XJ, Roop DR. Regulated cutaneous gene delivery: the skin as a bioreactor. Hum Gene Ther. 2000 Nov 01; 11(16):2297-300.
Score: 0.005
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Morton JJ, Alzofon N, Keysar SB, Chimed TS, Reisinger J, Perrenoud L, Le PN, Nieto C, Gomez K, Miller B, Yeager R, Gao D, Tan AC, Somerset H, Medina T, Wang XJ, Wang JH, Robinson W, Roop DR, Gonzalez R, Jimeno A. Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft. Mol Cancer Res. 2021 02; 19(2):346-357.
Score: 0.005
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Goldstein NB, Steel A, Barbulescu CC, Koster MI, Wright MJ, Jones KL, Gao B, Ward B, Woessner B, Trottier Z, Pakieser J, Hu J, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling. J Invest Dermatol. 2021 03; 141(3):638-647.e13.
Score: 0.005
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Ogawa T, Ishitsuka Y, Nakamura Y, Kubota N, Saito A, Fujisawa Y, Watanabe R, Okiyama N, Suga Y, Roop DR, Fujimoto M. NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy. J Immunol. 2020 08 15; 205(4):907-914.
Score: 0.005
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Suga Y, Arin MJ, Scott G, Goldsmith LA, Magro CM, Baden LA, Baden HP, Roop DR. Hot spot mutations in keratin 2e suggest a correlation between genotype and phenotype in patients with ichthyosis bullosa of Siemens. Exp Dermatol. 2000 Feb; 9(1):11-5.
Score: 0.005
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Arin MJ, Longley MA, Epstein EH, Rothnagel JA, Roop DR. Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis. Exp Dermatol. 2000 Feb; 9(1):16-9.
Score: 0.005
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Wang XJ, Liefer KM, Greenhalgh DA, Roop DR. 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation. Mol Carcinog. 1999 Dec; 26(4):305-11.
Score: 0.005
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Waikel RL, Wang XJ, Roop DR. Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene. 1999 Aug 26; 18(34):4870-8.
Score: 0.005
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Barbulescu CC, Goldstein NB, Roop DR, Norris DA, Birlea SA. Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata. J Invest Dermatol. 2020 01; 140(1):29-37.
Score: 0.005
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Bickenbach JR, Roop DR. Transduction of a preselected population of human epidermal stem cells: consequences for gene therapy. Proc Assoc Am Physicians. 1999 May-Jun; 111(3):184-9.
Score: 0.005
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Arin MJ, Longley MA, Anton-Lamprecht I, Kurze G, Huber M, Hohl D, Rothnagel JA, Roop DR. A novel substitution in keratin 10 in epidermolytic hyperkeratosis. J Invest Dermatol. 1999 Apr; 112(4):506-8.
Score: 0.005
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Lin MT, Levy ML, Bowden PE, Magro C, Baden L, Baden HP, Roop DR. Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot. Exp Dermatol. 1999 Apr; 8(2):115-9.
Score: 0.005
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Arin MJ, Longley MA, K?ster W, Huber M, Hohl D, Rothnagel JA, Roop DR. An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis. Exp Dermatol. 1999 Apr; 8(2):124-7.
Score: 0.005
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Arin MJ, Longley MA, Epstein EH, Scott G, Goldsmith LA, Rothnagel JA, Roop DR. A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens. J Invest Dermatol. 1999 Mar; 112(3):380-2.
Score: 0.004
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Suga Y, Duncan KO, Heald PW, Roop DR. A novel helix termination mutation in keratin 10 in annular epidermolytic ichthyosis, a variant of bullous congenital ichthyosiform erythroderma. J Invest Dermatol. 1998 Dec; 111(6):1220-3.
Score: 0.004
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Crumrine D, Khnykin D, Krieg P, Man MQ, Celli A, Mauro TM, Wakefield JS, Menon G, Mauldin E, Miner JH, Lin MH, Brash AR, Sprecher E, Radner FPW, Choate K, Roop D, Uchida Y, Gruber R, Schmuth M, Elias PM. Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte?Lipid Envelope. J Invest Dermatol. 2019 04; 139(4):760-768.
Score: 0.004
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Brinkley BR, Roop DR. Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function. Mol Carcinog. 1998 Nov; 23(3):185-92.
Score: 0.004
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Rothnagel JA, Lin MT, Longley MA, Holder RA, Hazen PG, Levy ML, Roop DR. Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis. Prenat Diagn. 1998 Aug; 18(8):826-30.
Score: 0.004
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Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45.
Score: 0.004
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Kogut I, McCarthy SM, Pavlova M, Astling DP, Chen X, Jakimenko A, Jones KL, Getahun A, Cambier JC, Pasmooij AMG, Jonkman MF, Roop DR, Bilousova G. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018 02 21; 9(1):745.
Score: 0.004
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Bonnekoh B, Greenhalgh DA, Chen SH, Bickenbach J, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model. Adv Exp Med Biol. 1998; 451:335-43.
Score: 0.004
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Goldstein NB, Koster MI, Jones KL, Gao B, Hoaglin LG, Robinson SE, Wright MJ, Birlea SI, Luman A, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA. Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the ?-Catenin Pathway in the Hair Follicle Bulge Stem Cells. J Invest Dermatol. 2018 03; 138(3):657-668.
Score: 0.004
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Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J. INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma. Oncogene. 2017 08 31; 36(35):4997-5005.
Score: 0.004
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Wang XJ, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R, Roop DR. Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2386-91.
Score: 0.004
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Joh GY, Traupe H, Metze D, Nashan D, Huber M, Hohl D, Longley MA, Rothnagel JA, Roop DR. A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma. J Invest Dermatol. 1997 Mar; 108(3):357-61.
Score: 0.004
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Bonnekoh B, Bickenbach JR, Roop DR. Immunological gene therapy approaches for malignant melanoma. 1. Tumor-immunological background. Skin Pharmacol. 1997; 10(2):49-62.
Score: 0.004
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Bonnekoh B, Bickenbach JR, Roop DR. Immunological gene therapy approaches for malignant melanoma. 2. Preclinical studies and clinical strategies. Skin Pharmacol. 1997; 10(3):105-25.
Score: 0.004
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Birlea SA, Costin GE, Roop DR, Norris DA. Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization. Med Res Rev. 2017 07; 37(4):907-935.
Score: 0.004
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Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA, Roop DR. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation. 1996 Dec; 61(2):129-39.
Score: 0.004
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Goldstein NB, Koster MI, Hoaglin LG, Wright MJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA. Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection. Exp Dermatol. 2016 10; 25(10):805-11.
Score: 0.004
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Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A. Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 01; 109(1).
Score: 0.004
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Greenhalgh DA, Wang XJ, Roop DR. Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox. J Investig Dermatol Symp Proc. 1996 Apr; 1(2):162-76.
Score: 0.004
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Bowles DW, Keysar SB, Eagles JR, Wang G, Glogowska MJ, McDermott JD, Le PN, Gao D, Ray CE, Rochon PJ, Roop DR, Tan AC, Serracino HS, Jimeno A. A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma. Oral Oncol. 2016 Feb; 53:74-9.
Score: 0.004
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Rothnagel JA, Roop DR. Hair follicle companion layer: reacquainting an old friend. J Invest Dermatol. 1995 May; 104(5 Suppl):42S-43S.
Score: 0.003
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Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene. 2016 Jan 21; 35(3):290-300.
Score: 0.003
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Goldstein NB, Koster MI, Hoaglin LG, Spoelstra NS, Kechris KJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA. Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors. J Invest Dermatol. 2015 Aug; 135(8):2068-2076.
Score: 0.003
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Rothnagel JA, Wojcik S, Liefer KM, Dominey AM, Huber M, Hohl D, Roop DR. Mutations in the 1A domain of keratin 9 in patients with epidermolytic palmoplantar keratoderma. J Invest Dermatol. 1995 Mar; 104(3):430-3.
Score: 0.003
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Roop D. Defects in the barrier. Science. 1995 Jan 27; 267(5197):474-5.
Score: 0.003
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Greenhalgh DA, Rothnagel JA, Roop DR. Epidermis: an attractive target tissue for gene therapy. J Invest Dermatol. 1994 Nov; 103(5 Suppl):63S-69S.
Score: 0.003
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Rothnagel JA, Longley MA, Bundman DS, Naylor SL, Lalley PA, Jenkins NA, Gilbert DJ, Copeland NG, Roop DR. Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3. Genomics. 1994 Sep 15; 23(2):450-6.
Score: 0.003
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Rothnagel JA, Traupe H, Wojcik S, Huber M, Hohl D, Pittelkow MR, Saeki H, Ishibashi Y, Roop DR. Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens. Nat Genet. 1994 Aug; 7(4):485-90.
Score: 0.003
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Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR, Roop DR. Genetic disorders of keratin: are scarring alopecias a sub-set? J Dermatol Sci. 1994 Jul; 7 Suppl:S164-9.
Score: 0.003
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Lu B, Rothnagel JA, Longley MA, Tsai SY, Roop DR. Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. J Biol Chem. 1994 Mar 11; 269(10):7443-9.
Score: 0.003
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van Steensel MAM, Coulombe PA, Kaspar RL, Milstone LM, McLean IWH, Roop DR, Smith FJD, Sprecher E, Schwartz ME. Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting. J Invest Dermatol. 2014 Mar; 134(3):588-591.
Score: 0.003
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Sch?fer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. EMBO Mol Med. 2014 04; 6(4):442-57.
Score: 0.003
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Rothnagel JA, Longley MA, Holder RA, K?ster W, Roop DR. Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing. J Invest Dermatol. 1994 Jan; 102(1):13-6.
Score: 0.003
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Kogut I, Roop DR, Bilousova G. Differentiation of human induced pluripotent stem cells into a keratinocyte lineage. Methods Mol Biol. 2014; 1195:1-12.
Score: 0.003
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Greenhalgh DA, Quintanilla MI, Orengo CC, Barber JL, Eckhardt JN, Rothnagel JA, Roop DR. Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion. Cancer Res. 1993 Nov 01; 53(21):5071-5.
Score: 0.003
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Rothnagel JA, Greenhalgh DA, Wang XJ, Sellheyer K, Bickenbach JR, Dominey AM, Roop DR. Transgenic models of skin diseases. Arch Dermatol. 1993 Nov; 129(11):1430-6.
Score: 0.003
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Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR. Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene. J Invest Dermatol. 1993 Oct; 101(4):506-13.
Score: 0.003
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Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C. Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci. 2013 Sep 26; 14(10):19540-55.
Score: 0.003
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White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. Epithelial stem cell mutations that promote squamous cell carcinoma metastasis. J Clin Invest. 2013 Oct; 123(10):4390-404.
Score: 0.003
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Hohl D, Ruf Olano B, de Viragh PA, Huber M, Detrisac CJ, Schnyder UW, Roop DR. Expression patterns of loricrin in various species and tissues. Differentiation. 1993 Aug; 54(1):25-34.
Score: 0.003
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Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA. A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012; 7(11):e50634.
Score: 0.003
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Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells. 2012 Oct; 30(10):2100-13.
Score: 0.003
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Rothnagel JA, Dominey AM, Dempsey LD, Longley MA, Greenhalgh DA, Gagne TA, Huber M, Frenk E, Hohl D, Roop DR. Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis. Science. 1992 Aug 21; 257(5073):1128-30.
Score: 0.003
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Luo Y, Ellis LZ, Dallaglio K, Takeda M, Robinson WA, Robinson SE, Liu W, Lewis KD, McCarter MD, Gonzalez R, Norris DA, Roop DR, Spritz RA, Ahn NG, Fujita M. Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance. J Invest Dermatol. 2012 Oct; 132(10):2440-2450.
Score: 0.003
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Yuspa SH, Kraemer KH, Dlugosz AA, Roop DR, Kulesz-Martin M, Bickenbach JR. Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research. J Invest Dermatol. 2012 May; 132(5):1317-20.
Score: 0.003
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Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409.
Score: 0.003
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Hohl D, Lichti U, Breitkreutz D, Steinert PM, Roop DR. Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid. J Invest Dermatol. 1991 Apr; 96(4):414-8.
Score: 0.003
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Rosenthal DS, Steinert PM, Chung S, Huff CA, Johnson J, Yuspa SH, Roop DR. A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes. Cell Growth Differ. 1991 Feb; 2(2):107-13.
Score: 0.003
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Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF. p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. Pigment Cell Melanoma Res. 2010 Dec; 23(6):781-94.
Score: 0.003
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Chen D, Lin Q, Box N, Roop D, Ishii S, Matsuzaki K, Fan T, Hornyak TJ, Reed JA, Stavnezer E, Timchenko NA, Medrano EE. SKI knockdown inhibits human melanoma tumor growth in vivo. Pigment Cell Melanoma Res. 2009 Dec; 22(6):761-72.
Score: 0.002
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Fete M, vanBokhoven H, Clements SE, McKeon F, Roop DR, Koster MI, Missero C, Attardi LD, Lombillo VA, Ratovitski E, Julapalli M, Ruths D, Sybert VP, Siegfried EC, Bree AF. International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1885-93.
Score: 0.002
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Refaeli Y, Bhoumik A, Roop DR, Ronai ZA. Melanoma-initiating cells: a compass needed. EMBO Rep. 2009 Sep; 10(9):965-72.
Score: 0.002
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Stanley JR, Tanaka T, Mueller S, Klaus-Kovtun V, Roop D. Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies. J Clin Invest. 1988 Dec; 82(6):1864-70.
Score: 0.002
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Marinari B, Ballaro C, Koster MI, Giustizieri ML, Moretti F, Crosti F, Papoutsaki M, Karin M, Alema S, Chimenti S, Roop DR, Costanzo A. IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias. J Invest Dermatol. 2009 Jan; 129(1):60-9.
Score: 0.002
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Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. J Dermatol Sci. 2008 Sep; 51(3):151-7.
Score: 0.002
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Yuspa SH, Hennings H, Tucker RW, Jaken S, Kilkenny AE, Roop DR. Signal transduction for proliferation and differentiation in keratinocytes. Ann N Y Acad Sci. 1988; 548:191-6.
Score: 0.002
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Steinert PM, Roop DR. Molecular and cellular biology of intermediate filaments. Annu Rev Biochem. 1988; 57:593-625.
Score: 0.002
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Prigozhina NL, Zhong L, Hunter EA, Mikic I, Callaway S, Roop DR, Mancini MA, Zacharias DA, Price JH, McDonough PM. Plasma membrane assays and three-compartment image cytometry for high content screening. Assay Drug Dev Technol. 2007 Feb; 5(1):29-48.
Score: 0.002
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Geng S, Mezentsev A, Kalachikov S, Raith K, Roop DR, Panteleyev AA. Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function. J Cell Sci. 2006 Dec 01; 119(Pt 23):4901-12.
Score: 0.002
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Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 01; 299(1):122-36.
Score: 0.002
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Nguyen BC, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, Koster MI, Zhang Z, Wang J, Tommasi di Vignano A, Kitajewski J, Chiorino G, Roop DR, Missero C, Dotto GP. Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev. 2006 Apr 15; 20(8):1028-42.
Score: 0.002
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Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 06; 25(29):4027-32.
Score: 0.002
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Steinert PM, Steven AC, Roop DR. The molecular biology of intermediate filaments. Cell. 1985 Sep; 42(2):411-20.
Score: 0.002
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Steinert PM, Parry DA, Idler WW, Johnson LD, Steven AC, Roop DR. Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits. J Biol Chem. 1985 Jun 10; 260(11):7142-9.
Score: 0.002
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Krieg TM, Schafer MP, Cheng CK, Filpula D, Flaherty P, Steinert PM, Roop DR. Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem. 1985 May 25; 260(10):5867-70.
Score: 0.002
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Steinert PM, Idler WW, Zhou XM, Johnson LD, Parry DA, Steven AC, Roop DR. Structural and functional implications of amino acid sequences of keratin intermediate filament subunits. Ann N Y Acad Sci. 1985; 455:451-61.
Score: 0.002
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Bigelow RL, Chari NS, Unden AB, Spurgers KB, Lee S, Roop DR, Toftgard R, McDonnell TJ. Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1. J Biol Chem. 2004 Jan 09; 279(2):1197-205.
Score: 0.002
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Klug DB, Carter C, Crouch E, Roop D, Conti CJ, Richie ER. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11822-7.
Score: 0.001
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Rodr?guez-Villanueva J, Greenhalgh D, Wang XJ, Bundman D, Cho S, Delehedde M, Roop D, McDonnell TJ. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene. 1998 Feb 19; 16(7):853-63.
Score: 0.001
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Ishida-Yamamoto A, Eady RA, Watt FM, Roop DR, Hohl D, Iizuka H. Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem. 1996 Feb; 44(2):167-75.
Score: 0.001
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Ishida-Yamamoto A, Iizuka H, Manabe M, O'Guin WM, Hohl D, Kartasova T, Kuroki T, Roop DR, Eady RA. Altered distribution of keratinization markers in epidermolytic hyperkeratosis. Arch Dermatol Res. 1995; 287(8):705-11.
Score: 0.001
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Brown LJ, Geesin JC, Rothnagel JA, Roop DR, Gordon JS. Retinoic acid suppression of loricrin expression in reconstituted human skin cultured at the liquid-air interface. J Invest Dermatol. 1994 Jun; 102(6):886-90.
Score: 0.001
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Huber M, Scaletta C, Benathan M, Frenk E, Greenhalgh DA, Rothnagel JA, Roop DR, Hohl D. Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations. J Invest Dermatol. 1994 May; 102(5):691-4.
Score: 0.001
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Ishida-Yamamoto A, Hohl D, Roop DR, Iizuka H, Eady RA. Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia. Arch Dermatol Res. 1993; 285(8):491-8.
Score: 0.001
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Rosenthal DS, Griffiths CE, Yuspa SH, Roop DR, Voorhees JJ. Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13 but not keratins 1, 10, and 14. J Invest Dermatol. 1992 Mar; 98(3):343-50.
Score: 0.001
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Breitkreutz D, Boukamp P, Ryle CM, Stark HJ, Roop DR, Fusenig NE. Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Res. 1991 Aug 15; 51(16):4402-9.
Score: 0.001
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Hohl D, Mehrel T, Lichti U, Turner ML, Roop DR, Steinert PM. Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem. 1991 Apr 05; 266(10):6626-36.
Score: 0.001
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Rosenthal DS, Roop DR, Huff CA, Weiss JS, Ellis CN, Hamilton T, Voorhees JJ, Yuspa SH. Changes in photo-aged human skin following topical application of all-trans retinoic acid. J Invest Dermatol. 1990 Nov; 95(5):510-5.
Score: 0.001
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Stark HJ, Breitkreutz D, Limat A, Ryle CM, Roop D, Leigh I, Fusenig N. Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle. Eur J Cell Biol. 1990 Aug; 52(2):359-72.
Score: 0.001
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Thrane PS, Roop DR, Sollid LM, Huitfeldt HS, Brandtzaeg P. Two-colour immunofluorescence marker study of pleomorphic adenomas. Histochemistry. 1990; 93(5):459-68.
Score: 0.001
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Ryle CM, Breitkreutz D, Stark HJ, Leigh IM, Steinert PM, Roop D, Fusenig NE. Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation. 1989 Mar; 40(1):42-54.
Score: 0.001
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Luo W, Roop DR, Lau EC, Melrose RJ, Mostofi R, Stenman G, Snead ML. In situ hybridization analysis of keratin gene expression in human ameloblastomas. J Oral Pathol. 1988 Nov; 17(9-10):534-40.
Score: 0.001
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Zhou XM, Idler WW, Steven AC, Roop DR, Steinert PM. The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences. J Biol Chem. 1988 Oct 25; 263(30):15584-9.
Score: 0.001
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Johnson LD, Idler WW, Zhou XM, Roop DR, Steinert PM. Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A. 1985 Apr; 82(7):1896-900.
Score: 0.000
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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