 Connection
Sean Colgan to Colitis
This is a "connection" page, showing publications Sean Colgan has written about Colitis.
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Connection Strength |
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8.260 |
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Lee JS, Kao DJ, Worledge CS, Villamaria ZF, Wang RX, Welch NM, Kostelecky RE, Colgan SP. E. coli genetically modified for purine nucleobase release promotes butyrate generation and colonic wound healing during DSS insult. Gut Microbes. 2025 Dec; 17(1):2490211.
Score: 0.717
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Hall CHT, Lanis JM, Dowdell AS, Murphy EM, Bhagavatula G, Neuhart RM, Vijaya Sai KY, Colgan SP. Fundamental role for the creatine kinase pathway in protection from murine colitis. Mucosal Immunol. 2023 12; 16(6):817-825.
Score: 0.642
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Alexeev EE, Dowdell AS, Henen MA, Lanis JM, Lee JS, Cartwright IM, Schaefer REM, Ornelas A, Onyiah JC, Vögeli B, Colgan SP. Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage. FASEB J. 2021 05; 35(5):e21552.
Score: 0.545
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Cartwright IM, Curtis VF, Lanis JM, Alexeev EE, Welch N, Goldberg MS, Schaefer REM, Gao RY, Chun C, Fennimore B, Onyiah JC, Gerich ME, Dempsey PJ, Colgan SP. Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3. Mucosal Immunol. 2020 03; 13(2):230-244.
Score: 0.494
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Lee JS, Wang RX, Alexeev EE, Lanis JM, Battista KD, Glover LE, Colgan SP. Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function. J Biol Chem. 2018 04 20; 293(16):6039-6051.
Score: 0.437
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Alexeev EE, Lanis JM, Kao DJ, Campbell EL, Kelly CJ, Battista KD, Gerich ME, Jenkins BR, Walk ST, Kominsky DJ, Colgan SP. Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor. Am J Pathol. 2018 05; 188(5):1183-1194.
Score: 0.436
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Lanis JM, Alexeev EE, Curtis VF, Kitzenberg DA, Kao DJ, Battista KD, Gerich ME, Glover LE, Kominsky DJ, Colgan SP. Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia. Mucosal Immunol. 2017 09; 10(5):1133-1144.
Score: 0.405
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Campbell EL, Bruyninckx WJ, Kelly CJ, Glover LE, McNamee EN, Bowers BE, Bayless AJ, Scully M, Saeedi BJ, Golden-Mason L, Ehrentraut SF, Curtis VF, Burgess A, Garvey JF, Sorensen A, Nemenoff R, Jedlicka P, Taylor CT, Kominsky DJ, Colgan SP. Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation. Immunity. 2014 Jan 16; 40(1):66-77.
Score: 0.328
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Glover LE, Bowers BE, Saeedi B, Ehrentraut SF, Campbell EL, Bayless AJ, Dobrinskikh E, Kendrick AA, Kelly CJ, Burgess A, Miller L, Kominsky DJ, Jedlicka P, Colgan SP. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19820-5.
Score: 0.325
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Keely S, Campbell EL, Baird AW, Hansbro PM, Shalwitz RA, Kotsakis A, McNamee EN, Eltzschig HK, Kominsky DJ, Colgan SP. Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis. Mucosal Immunol. 2014 Jan; 7(1):114-23.
Score: 0.314
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Kominsky DJ, Keely S, MacManus CF, Glover LE, Scully M, Collins CB, Bowers BE, Campbell EL, Colgan SP. An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. J Immunol. 2011 Jun 01; 186(11):6505-14.
Score: 0.272
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Glover LE, Irizarry K, Scully M, Campbell EL, Bowers BE, Aherne CM, Kominsky DJ, MacManus CF, Colgan SP. IFN-? attenuates hypoxia-inducible factor (HIF) activity in intestinal epithelial cells through transcriptional repression of HIF-1ß. J Immunol. 2011 Feb 01; 186(3):1790-8.
Score: 0.266
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Frick JS, MacManus CF, Scully M, Glover LE, Eltzschig HK, Colgan SP. Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis. J Immunol. 2009 Apr 15; 182(8):4957-64.
Score: 0.236
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Robinson A, Keely S, Karhausen J, Gerich ME, Furuta GT, Colgan SP. Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. Gastroenterology. 2008 Jan; 134(1):145-55.
Score: 0.216
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Yang Y, Atkins CL, Fan Y, Hou L, Zhao J, Gao J, Wen Y, Moreno NF, Huang X, Bishehsari F, Czopik AK, Colgan SP, Purnak T, Summa KC, Cong Y, Jacobsen EA, Ju C. Eosinophil-derived COX-2 protects against experimental colitis through the PGE2-IL-22 axis. Proc Natl Acad Sci U S A. 2026 May 12; 123(19):e2525334123.
Score: 0.193
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Ornelas A, Countess JA, Kim JY, Cohen RH, Gomez BD, Roer RL, Minhajuddin F, Yenugudhati Vijaya Sai K, Zhou L, Dunn JLM, Chandler C, Reigan P, Cartwright IM, Hall CHT, Bhagavatula G, Onyiah JC, Dowdell AS, Colgan SP. Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa. Proc Natl Acad Sci U S A. 2026 Apr 14; 123(15):e2527863123.
Score: 0.192
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Callahan RC, Curry JC, Bhagavatula G, Staley AW, Schaefer RE, Minhajuddin F, Zhou L, Neuhart RM, Atif SM, Orlicky DJ, Cartwright IM, Gerich ME, Steiner CA, Theiss AL, Hall CH, Colgan SP, Onyiah JC. Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner. JCI Insight. 2026 Feb 09; 11(3).
Score: 0.188
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Bhagavatula G, Worledge CS, Schaepe C, Murphy EM, Neuhart RM, Lee JS, Cartwright I, Colgan SP, Hall CHT. Phosphocreatine Rescues Intestinal Epithelial Metabolic Dysfunction Related to Creatine Kinase Loss and Is Protective in Murine Colitis. Cell Mol Gastroenterol Hepatol. 2025; 19(11):101557.
Score: 0.181
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Cartwright IM, Zhou L, Koch SD, Welch N, Zakharov D, Callahan R, Steiner CA, Gerich ME, Onyiah JC, Colgan SP. Chlorination of epithelial tight junction proteins by neutrophil myeloperoxidase promotes barrier dysfunction and mucosal inflammation. JCI Insight. 2024 06 11; 9(14).
Score: 0.169
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Worledge CS, Kostelecky RE, Zhou L, Bhagavatula G, Colgan SP, Lee JS. Allopurinol Disrupts Purine Metabolism to Increase Damage in Experimental Colitis. Cells. 2024 02 21; 13(5).
Score: 0.165
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de Graaf DM, Wang RX, Amo-Aparicio J, Lee JS, Dowdell AS, Tengesdal IW, Marchetti C, Colgan SP, Joosten LAB, Dinarello CA. IL-38 Gene Deletion Worsens Murine Colitis. Front Immunol. 2022; 13:840719.
Score: 0.147
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Schaefer REM, Callahan RC, Atif SM, Orlicky DJ, Cartwright IM, Fontenot AP, Colgan SP, Onyiah JC. Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation. Mucosal Immunol. 2022 02; 15(2):244-256.
Score: 0.142
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Gao RY, Shearn CT, Orlicky DJ, Battista KD, Alexeev EE, Cartwright IM, Lanis JM, Kostelecky RE, Ju C, Colgan SP, Fennimore BP. Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis. Mucosal Immunol. 2021 03; 14(2):479-490.
Score: 0.131
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Liu G, Baird AW, Parsons MJ, Fan K, Skerrett-Byrne DA, Nair PM, Makanyengo S, Chen J, Neal R, Goggins BJ, Tay H, Mathe A, Soh WS, Minahan K, Hansbro PM, Nixon B, McCaughan GW, Holtmann G, Colgan SP, Keely S. Platelet activating factor receptor acts to limit colitis-induced liver inflammation. FASEB J. 2020 06; 34(6):7718-7732.
Score: 0.127
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Kelly CJ, Alexeev EE, Farb L, Vickery TW, Zheng L, Eric L C, Kitzenberg DA, Battista KD, Kominsky DJ, Robertson CE, Frank DN, Stabler SP, Colgan SP. Oral vitamin B12 supplement is delivered to the distal gut, altering the corrinoid profile and selectively depleting Bacteroides in C57BL/6 mice. Gut Microbes. 2019; 10(6):654-662.
Score: 0.119
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Onyiah JC, Schaefer REM, Colgan SP. A Central Role for Heme Oxygenase-1 in the Control of Intestinal Epithelial Chemokine Expression. J Innate Immun. 2018; 10(3):228-238.
Score: 0.111
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Chun C, Zheng L, Colgan SP. Tissue metabolism and host-microbial interactions in the intestinal mucosa. Free Radic Biol Med. 2017 04; 105:86-92.
Score: 0.099
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Frasch SC, McNamee EN, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, Mack M, Furuta GT, Lee JJ, Henson PM, Colgan SP, Bratton DL. G2A Signaling Dampens Colitic Inflammation via Production of IFN-?. J Immunol. 2016 08 15; 197(4):1425-34.
Score: 0.098
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Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK. Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunol. 2015 Nov; 8(6):1324-38.
Score: 0.089
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Masterson JC, McNamee EN, Fillon SA, Hosford L, Harris R, Fernando SD, Jedlicka P, Iwamoto R, Jacobsen E, Protheroe C, Eltzschig HK, Colgan SP, Arita M, Lee JJ, Furuta GT. Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis. Gut. 2015 Aug; 64(8):1236-47.
Score: 0.086
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MacManus CF, Campbell EL, Keely S, Burgess A, Kominsky DJ, Colgan SP. Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization. FASEB J. 2011 Jun; 25(6):1856-64.
Score: 0.067
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Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis. 2011 Jun; 17(6):1359-72.
Score: 0.065
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Campbell EL, MacManus CF, Kominsky DJ, Keely S, Glover LE, Bowers BE, Scully M, Bruyninckx WJ, Colgan SP. Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14298-303.
Score: 0.065
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Keely S, Glover LE, MacManus CF, Campbell EL, Scully MM, Furuta GT, Colgan SP. Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing. FASEB J. 2009 May; 23(5):1338-46.
Score: 0.058
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Louis NA, Robinson AM, MacManus CF, Karhausen J, Scully M, Colgan SP. Control of IFN-alphaA by CD73: implications for mucosal inflammation. J Immunol. 2008 Mar 15; 180(6):4246-55.
Score: 0.055
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Karhausen J, Furuta GT, Tomaszewski JE, Johnson RS, Colgan SP, Haase VH. Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. J Clin Invest. 2004 Oct; 114(8):1098-106.
Score: 0.043
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Kominsky DJ, Campbell EL, Ehrentraut SF, Wilson KE, Kelly CJ, Glover LE, Collins CB, Bayless AJ, Saeedi B, Dobrinskikh E, Bowers BE, MacManus CF, Müller W, Colgan SP, Bruder D. IFN-?-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia. J Immunol. 2014 Feb 01; 192(3):1267-76.
Score: 0.020
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Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2784-93.
Score: 0.019
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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