 Connection
Jeffrey Kieft to RNA, Viral
This is a "connection" page, showing publications Jeffrey Kieft has written about RNA, Viral.
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Connection Strength |
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14.305 |
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Spear E, O'Donoghue Z, Bonilla SL, Larsen KP, Sherlock ME, Kieft JS. A structural bridge between dengue virus tandem xrRNAs facilitates coordination of exonuclease resistance. mBio. 2026 Sep 09; 17(9):e0155326.
Score: 0.728
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Segar KE, Sherlock ME, Kieft JS. Distribution and structural diversity of type IV internal ribosome entry sites. RNA. 2026 04 16; 32(5):622-634.
Score: 0.712
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Langeberg CJ, Szucs MJ, Sherlock ME, Vicens Q, Kieft JS. Tick-borne flavivirus exoribonuclease-resistant RNAs contain a double loop structure. Nat Commun. 2025 May 15; 16(1):4515.
Score: 0.668
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Sherlock ME, Langeberg CJ, Segar KE, Kieft JS. A conserved class of viral RNA structures regulates translation reinitiation through dynamic ribosome interactions. Cell Rep. 2025 02 25; 44(2):115236.
Score: 0.655
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Bonilla SL, Sherlock ME, MacFadden A, Kieft JS. A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. Science. 2021 Nov 19; 374(6570):955-960.
Score: 0.524
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Akiyama BM, Graham ME, O Donoghue Z, Beckham JD, Kieft JS. Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Res. 2021 07 09; 49(12):7122-7138.
Score: 0.511
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Sherlock ME, Hartwick EW, MacFadden A, Kieft JS. Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses. RNA. 2021 01; 27(1):27-39.
Score: 0.485
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Jones RA, Steckelberg AL, Vicens Q, Szucs MJ, Akiyama BM, Kieft JS. Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA. RNA. 2021 01; 27(1):54-65.
Score: 0.485
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Szucs MJ, Nichols PJ, Jones RA, Vicens Q, Kieft JS. A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of Flaviviridae. mBio. 2020 09 29; 11(5).
Score: 0.485
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Steckelberg AL, Vicens Q, Costantino DA, Nix JC, Kieft JS. The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. RNA. 2020 12; 26(12):1767-1776.
Score: 0.481
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Jaafar ZA, Kieft JS. Viral RNA structure-based strategies to manipulate translation. Nat Rev Microbiol. 2019 01; 17(2):110-123.
Score: 0.429
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Steckelberg AL, Vicens Q, Kieft JS. Exoribonuclease-Resistant RNAs Exist within both Coding and Noncoding Subgenomic RNAs. mBio. 2018 12 18; 9(6).
Score: 0.428
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Steckelberg AL, Akiyama BM, Costantino DA, Sit TL, Nix JC, Kieft JS. A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):6404-6409.
Score: 0.413
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MacFadden A, O'Donoghue Z, Silva PAGC, Chapman EG, Olsthoorn RC, Sterken MG, Pijlman GP, Bredenbeek PJ, Kieft JS. Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs. Nat Commun. 2018 01 09; 9(1):119.
Score: 0.401
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Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science. 2016 12 02; 354(6316):1148-1152.
Score: 0.370
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Hao Y, Kieft JS. Three-way junction conformation dictates self-association of phage packaging RNAs. RNA Biol. 2016 07 02; 13(7):635-45.
Score: 0.358
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Ruehle MD, Zhang H, Sheridan RM, Mitra S, Chen Y, Gonzalez RL, Cooperman BS, Kieft JS. A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation. Elife. 2015 Nov 02; 4.
Score: 0.345
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Kieft JS, Rabe JL, Chapman EG. New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation. RNA Biol. 2015; 12(11):1169-77.
Score: 0.342
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Hao Y, Kieft JS. Diverse self-association properties within a family of phage packaging RNAs. RNA. 2014 Nov; 20(11):1759-74.
Score: 0.319
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Colussi TM, Costantino DA, Hammond JA, Ruehle GM, Nix JC, Kieft JS. The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature. 2014 Jul 17; 511(7509):366-9.
Score: 0.313
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Chapman EG, Costantino DA, Rabe JL, Moon SL, Wilusz J, Nix JC, Kieft JS. The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production. Science. 2014 Apr 18; 344(6181):307-10.
Score: 0.310
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Chapman EG, Moon SL, Wilusz J, Kieft JS. RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA. Elife. 2014 Apr 01; 3:e01892.
Score: 0.309
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Plank TD, Whitehurst JT, Kieft JS. Cell type specificity and structural determinants of IRES activity from the 5' leaders of different HIV-1 transcripts. Nucleic Acids Res. 2013 Jul; 41(13):6698-714.
Score: 0.290
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Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nat Struct Mol Biol. 2013 Feb; 20(2):150-8.
Score: 0.283
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Filbin ME, Kieft JS. HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove. RNA. 2011 Jul; 17(7):1258-73.
Score: 0.253
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Zhu J, Korostelev A, Costantino DA, Donohue JP, Noller HF, Kieft JS. Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1839-44.
Score: 0.247
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Hammond JA, Rambo RP, Kieft JS. Multi-domain packing in the aminoacylatable 3' end of a plant viral RNA. J Mol Biol. 2010 Jun 11; 399(3):450-63.
Score: 0.235
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Hammond JA, Rambo RP, Filbin ME, Kieft JS. Comparison and functional implications of the 3D architectures of viral tRNA-like structures. RNA. 2009 Feb; 15(2):294-307.
Score: 0.216
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Kieft J, Martinez-Salas E. Preface: functionally critical RNA structures found in positive-sense RNA viruses. Virus Res. 2009 Feb; 139(2):135-6.
Score: 0.210
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Kieft JS. Comparing the three-dimensional structures of Dicistroviridae IGR IRES RNAs with other viral RNA structures. Virus Res. 2009 Feb; 139(2):148-56.
Score: 0.209
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Pfingsten JS, Kieft JS. RNA structure-based ribosome recruitment: lessons from the Dicistroviridae intergenic region IRESes. RNA. 2008 Jul; 14(7):1255-63.
Score: 0.206
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Kieft JS. Viral IRES RNA structures and ribosome interactions. Trends Biochem Sci. 2008 Jun; 33(6):274-83.
Score: 0.206
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Pfingsten JS, Costantino DA, Kieft JS. Conservation and diversity among the three-dimensional folds of the Dicistroviridae intergenic region IRESes. J Mol Biol. 2007 Jul 27; 370(5):856-69.
Score: 0.191
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Pfingsten JS, Costantino DA, Kieft JS. Structural basis for ribosome recruitment and manipulation by a viral IRES RNA. Science. 2006 Dec 01; 314(5804):1450-4.
Score: 0.186
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Sherlock ME, Segar KE, Kieft JS. A bicistronic viral genome uses a compact type IV IRES near its 3' end to express a transmembrane protein. Cell Rep. 2026 Feb 24; 45(2):116982.
Score: 0.176
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Costantino D, Kieft JS. A preformed compact ribosome-binding domain in the cricket paralysis-like virus IRES RNAs. RNA. 2005 Mar; 11(3):332-43.
Score: 0.165
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Sherlock ME, Langeberg CJ, Kieft JS. Diversity and modularity of tyrosine-accepting tRNA-like structures. RNA. 2024 02 16; 30(3):213-222.
Score: 0.153
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Kieft JS, Zhou K, Grech A, Jubin R, Doudna JA. Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nat Struct Biol. 2002 May; 9(5):370-4.
Score: 0.135
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Kieft JS, Zhou K, Jubin R, Doudna JA. Mechanism of ribosome recruitment by hepatitis C IRES RNA. RNA. 2001 Feb; 7(2):194-206.
Score: 0.124
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Sparks H, Monogue B, Akiyama B, Kieft J, Beckham JD. Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication. Viruses. 2020 10 18; 12(10).
Score: 0.122
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Kieft JS, Zhou K, Jubin R, Murray MG, Lau JY, Doudna JA. The hepatitis C virus internal ribosome entry site adopts an ion-dependent tertiary fold. J Mol Biol. 1999 Sep 24; 292(3):513-29.
Score: 0.113
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Hartwick EW, Costantino DA, MacFadden A, Nix JC, Tian S, Das R, Kieft JS. Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels. Nat Commun. 2018 11 29; 9(1):5074.
Score: 0.107
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Akiyama BM, Eiler D, Kieft JS. Structured RNAs that evade or confound exonucleases: function follows form. Curr Opin Struct Biol. 2016 Feb; 36:40-7.
Score: 0.087
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Colussi TM, Costantino DA, Zhu J, Donohue JP, Korostelev AA, Jaafar ZA, Plank TD, Noller HF, Kieft JS. Initiation of translation in bacteria by a structured eukaryotic IRES RNA. Nature. 2015 Mar 05; 519(7541):110-3.
Score: 0.082
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Vallejos M, Deforges J, Plank TD, Letelier A, Ramdohr P, Abraham CG, Valiente-Echeverría F, Kieft JS, Sargueil B, López-Lastra M. Activity of the human immunodeficiency virus type 1 cell cycle-dependent internal ribosomal entry site is modulated by IRES trans-acting factors. Nucleic Acids Res. 2011 Aug; 39(14):6186-200.
Score: 0.063
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Costantino DA, Pfingsten JS, Rambo RP, Kieft JS. tRNA-mRNA mimicry drives translation initiation from a viral IRES. Nat Struct Mol Biol. 2008 Jan; 15(1):57-64.
Score: 0.050
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Rijnbrand R, Bredenbeek PJ, Haasnoot PC, Kieft JS, Spaan WJ, Lemon SM. The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs. RNA. 2001 Apr; 7(4):585-97.
Score: 0.031
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Spahn CM, Kieft JS, Grassucci RA, Penczek PA, Zhou K, Doudna JA, Frank J. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science. 2001 Mar 09; 291(5510):1959-62.
Score: 0.031
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Kieft JS, Grech A, Adams P, Doudna JA. Mechanisms of internal ribosome entry in translation initiation. Cold Spring Harb Symp Quant Biol. 2001; 66:277-83.
Score: 0.031
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Jubin R, Vantuno NE, Kieft JS, Murray MG, Doudna JA, Lau JY, Baroudy BM. Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding. J Virol. 2000 Nov; 74(22):10430-7.
Score: 0.030
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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