BrianKempfBrian J. Kempf39.74545800000000-104.839369100000001863Kempf, BrianJ.303/724-4263Research Associateprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 865952Authorship 880992Authorship 126271125559071Kempf BJ, Barton DJVirus researchKempf BJ, Barton DJ. Picornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerase. Virus Res. 2015 Aug 03; 206:3-11.Virus Res2015-01-03T00:00:002015Picornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerase.Authorship 962912JaredKlarquistJared S Klarquist39.74545800000000-104.8393691000000011772Klarquist, JaredAsst Professor-ResearchAuthorship 149310127412593Kempf BJ, Peersen OB, Barton DJJournal of virologyKempf BJ, Peersen OB, Barton DJ. Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance. J Virol. 2016 10 01; 90(19):8410-21.J Virol2016-09-12T00:00:002016Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance.11714967Borucki MK, Kempf BJ, Blair CD, Beaty BJThe Journal of general virologyBorucki MK, Kempf BJ, Blair CD, Beaty BJ. The effect of mosquito passage on the La Crosse virus genotype. J Gen Virol. 2001 Dec; 82(Pt 12):2919-2926.J Gen Virol2001-12-01T00:00:002001The effect of mosquito passage on the La Crosse virus genotype.11909745Borucki MK, Kempf BJ, Blitvich BJ, Blair CD, Beaty BJMicrobes and infectionBorucki MK, Kempf BJ, Blitvich BJ, Blair CD, Beaty BJ. La Crosse virus: replication in vertebrate and invertebrate hosts. Microbes Infect. 2002 Mar; 4(3):341-50.Microbes Infect2002-03-01T00:00:002002La Crosse virus: replication in vertebrate and invertebrate hosts.5Other Faculty1Professor3Asst Professor7Fellow or Post Doc16474075Kempf BJ, Blair CD, Beaty BJThe American journal of tropical medicine and hygieneKempf BJ, Blair CD, Beaty BJ. Quantitative analysis of La Crosse virus transcription and replication in cell cultures and mosquitoes. Am J Trop Med Hyg. 2006 Feb; 74(2):224-32.Am J Trop Med Hyg2006-02-01T00:00:002006Quantitative analysis of La Crosse virus transcription and replication in cell cultures and mosquitoes.12800 E 19th Ave2RC1NResearch North Tower12800 E 19th AveAurora80045-2537COBradySpencerBrady Spencer39.74545800000000-104.8393691000000013040Spencer, BradyPost-Doctoral FellowMamukaKvaratskheliaMamuka Kvaratskhelia39.74528180000000-104.8375727000000013174Kvaratskhelia, MamukaProfessor20534858Hobdey SE, Kempf BJ, Steil BP, Barton DJ, Peersen OBJournal of virologyHobdey SE, Kempf BJ, Steil BP, Barton DJ, Peersen OB. Poliovirus polymerase residue 5 plays a critical role in elongation complex stability. J Virol. 2010 Aug; 84(16):8072-84.J Virol2010-06-09T00:00:002010Poliovirus polymerase residue 5 plays a critical role in elongation complex stability.DavidWylesDavid L. Wyles39.74528180000000-104.8375727000000013536Wyles, DavidAffiliate - DHHA22215596Shimakami T, Yamane D, Jangra RK, Kempf BJ, Spaniel C, Barton DJ, Lemon SMProceedings of the National Academy of Sciences of the United States of AmericaShimakami T, Yamane D, Jangra RK, Kempf BJ, Spaniel C, Barton DJ, Lemon SM. Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):941-6.Proc Natl Acad Sci U S A2012-01-03T00:00:002012Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex.23468507Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJJournal of virologyKempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ. Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA. J Virol. 2013 May; 87(10):5629-44.J Virol2013-03-06T00:00:002013Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA.18400852Kempf BJ, Barton DJJournal of virologyKempf BJ, Barton DJ. Poliovirus 2A(Pro) increases viral mRNA and polysome stability coordinately in time with cleavage of eIF4G. J Virol. 2008 Jun; 82(12):5847-59.J Virol2008-04-09T00:00:002008Poliovirus 2A(Pro) increases viral mRNA and polysome stability coordinately in time with cleavage of eIF4G.18400854Kempf BJ, Barton DJJournal of virologyKempf BJ, Barton DJ. Poly(rC) binding proteins and the 5' cloverleaf of uncapped poliovirus mRNA function during de novo assembly of polysomes. J Virol. 2008 Jun; 82(12):5835-46.J Virol2008-04-09T00:00:002008Poly(rC) binding proteins and the 5' cloverleaf of uncapped poliovirus mRNA function during de novo assembly of polysomes.20071574Steil BP, Kempf BJ, Barton DJJournal of virologySteil BP, Kempf BJ, Barton DJ. Poly(A) at the 3' end of positive-strand RNA and VPg-linked poly(U) at the 5' end of negative-strand RNA are reciprocal templates during replication of poliovirus RNA. J Virol. 2010 Mar; 84(6):2843-58.J Virol2010-01-13T00:00:002010Poly(A) at the 3' end of positive-strand RNA and VPg-linked poly(U) at the 5' end of negative-strand RNA are reciprocal templates during replication of poliovirus RNA.22321798Kortus MG, Kempf BJ, Haworth KG, Barton DJ, Peersen OBJournal of molecular biologyKortus MG, Kempf BJ, Haworth KG, Barton DJ, Peersen OB. A template RNA entry channel in the fingers domain of the poliovirus polymerase. J Mol Biol. 2012 Apr 06; 417(4):263-78.J Mol Biol2012-02-01T00:00:002012A template RNA entry channel in the fingers domain of the poliovirus polymerase.D017955Living Beings20770.936439PoliovirusD012367Chemicals & Drugs2015970.74488RNA, ViralAuthorship 200202131068422Kempf BJ, Watkins CL, Peersen OB, Barton DJJournal of virologyKempf BJ, Watkins CL, Peersen OB, Barton DJ. Picornavirus RNA Recombination Counteracts Error Catastrophe. J Virol. 2019 07 15; 93(14).J Virol2019-06-28T00:00:002019Picornavirus RNA Recombination Counteracts Error Catastrophe.SOM-IMM MICRO GENERAL OPERD011995Physiology1121750.907054Recombination, GeneticD010849Living Beings11180.972254PicornaviridaeD012254Chemicals & Drugs33890.919432RibavirinSOM-BioChem&Molecular GeneticsSOM-MEDInfectious DiseaseUniversity of Colorado Denver - Anschutz Medical CampusLindavan DykLinda Faye van Dyk39.74545800000000-104.839369100000001628van Dyk, LindaProfessorJillSlanskyJill E Slansky39.74545800000000-104.839369100000001693Slansky, JillProfessor2.922820.0019900285research areas3.960543.960541coauthor of61.98031.8390160similar to1115selected publicationsJeffreyKieftJeffrey Scott Kieft39.74389450000000-104.839435200000001812Kieft, JeffreyProfessor AdjointDavidBartonDavid J Barton39.74545800000000-104.83936910000000457Barton, DavidProfessorAuthorship 221354232493771Watkins CL, Kempf BJ, Beaucourt S, Barton DJ, Peersen OBThe Journal of biological chemistryWatkins CL, Kempf BJ, Beaucourt S, Barton DJ, Peersen OB. Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases. J Biol Chem. 2020 07 31; 295(31):10624-10637.J Biol Chem2020-06-03T00:00:002020Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases.Authorship 221537132522851Kempf BJ, Watkins CL, Peersen OB, Barton DJJournal of virologyKempf BJ, Watkins CL, Peersen OB, Barton DJ. An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms. J Virol. 2020 07 30; 94(16).J Virol2020-07-30T00:00:002020An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms.true1Affiliate - DHHAAffiliate - DHHAtrue1ProfessorProfessorAuthorship 309711true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Professor AdjointProfessor Adjointtrue1Post-Doctoral FellowPost-Doctoral Fellowtrue1Research AssociateResearch Associatetrue1Asst Professor-ResearchAsst Professor-Researchtrue1ProfessorProfessorJenniferMatsudaJennifer Louise Matsuda39.74545800000000-104.839369100000008451Matsuda, JenniferProfessorAuthorship 547982Authorship 568532Authorship 588021Authorship 60981EricPoeschlaEric M Poeschla39.74528180000000-104.837572700000009025Poeschla, EricProfessorAuthorship 656771Authorship 730614