Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Genevieve Sparagna to Cardiolipins

This is a "connection" page, showing publications Genevieve Sparagna has written about Cardiolipins.

 
Connection Strength
 
 
 
4.423
 
  1. Zachman DK, Chicco AJ, McCune SA, Murphy RC, Moore RL, Sparagna GC. The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart. J Lipid Res. 2010 Mar; 51(3):525-34.
    View in: PubMed
    Score: 0.309
  2. Sparagna GC, Lesnefsky EJ. Cardiolipin remodeling in the heart. J Cardiovasc Pharmacol. 2009 Apr; 53(4):290-301.
    View in: PubMed
    Score: 0.299
  3. Saini-Chohan HK, Holmes MG, Chicco AJ, Taylor WA, Moore RL, McCune SA, Hickson-Bick DL, Hatch GM, Sparagna GC. Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure. J Lipid Res. 2009 Aug; 50(8):1600-8.
    View in: PubMed
    Score: 0.291
  4. Sparagna GC, Chicco AJ, Murphy RC, Bristow MR, Johnson CA, Rees ML, Maxey ML, McCune SA, Moore RL. Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure. J Lipid Res. 2007 Jul; 48(7):1559-70.
    View in: PubMed
    Score: 0.261
  5. Chicco AJ, Sparagna GC. Role of cardiolipin alterations in mitochondrial dysfunction and disease. Am J Physiol Cell Physiol. 2007 Jan; 292(1):C33-44.
    View in: PubMed
    Score: 0.249
  6. Eke C, Babcock S, Gaston G, Elizondo G, Chung H, Asal A, Chatfield KC, Sparagna GC, DeBarber AE, Packwood W, Lindner JR, Gillingham MB. Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species. J Lipid Res. 2025 May; 66(5):100792.
    View in: PubMed
    Score: 0.227
  7. Sparagna GC, Johnson CA, McCune SA, Moore RL, Murphy RC. Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry. J Lipid Res. 2005 Jun; 46(6):1196-204.
    View in: PubMed
    Score: 0.226
  8. Mahler CA, Snoke DB, Cole RM, Angelotti A, Sparagna GC, Baskin KK, Ni A, Belury MA. Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration. J Nutr. 2024 03; 154(3):856-865.
    View in: PubMed
    Score: 0.208
  9. Zegallai HM, Abu-El-Rub E, Mejia EM, Sparagna GC, Cole LK, Marshall AJ, Hatch GM. Tafazzin deficiency attenuates anti-cluster of differentiation 40 and interleukin-4 activation of mouse B lymphocytes. Cell Tissue Res. 2022 Dec; 390(3):429-439.
    View in: PubMed
    Score: 0.190
  10. Cole LK, Sparagna GC, Dolinsky VW, Hatch GM. Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups. PLoS One. 2022; 17(2):e0263520.
    View in: PubMed
    Score: 0.182
  11. Cole LK, Sparagna GC, Vandel M, Xiang B, Dolinsky VW, Hatch GM. Berberine elevates cardiolipin in heart of offspring from mouse dams with high fat diet-induced gestational diabetes mellitus. Sci Rep. 2021 08 04; 11(1):15770.
    View in: PubMed
    Score: 0.176
  12. Cole LK, Mejia EM, Sparagna GC, Vandel M, Xiang B, Han X, Dedousis N, Kaufman BA, Dolinsky VW, Hatch GM. Cardiolipin deficiency elevates susceptibility to a lipotoxic hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2020 07; 144:24-34.
    View in: PubMed
    Score: 0.162
  13. Garcia AM, McPhaul JC, Sparagna GC, Jeffrey DA, Jonscher R, Patel SS, Sucharov CC, Stauffer BL, Miyamoto SD, Chatfield KC. Alteration of cardiolipin biosynthesis and remodeling in single right ventricle congenital heart disease. Am J Physiol Heart Circ Physiol. 2020 04 01; 318(4):H787-H800.
    View in: PubMed
    Score: 0.159
  14. Cole LK, Mejia EM, Vandel M, Sparagna GC, Claypool SM, Dyck-Chan L, Klein J, Hatch GM. Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity. Diabetes. 2016 Nov; 65(11):3289-3300.
    View in: PubMed
    Score: 0.124
  15. Dolinsky VW, Cole LK, Sparagna GC, Hatch GM. Cardiac mitochondrial energy metabolism in heart failure: Role of cardiolipin and sirtuins. Biochim Biophys Acta. 2016 10; 1861(10):1544-54.
    View in: PubMed
    Score: 0.121
  16. Mejia EM, Chau S, Sparagna GC, Sipione S, Hatch GM. Reduced Mitochondrial Function in Human Huntington Disease Lymphoblasts is Not Due to Alterations in Cardiolipin Metabolism or Mitochondrial Supercomplex Assembly. Lipids. 2016 05; 51(5):561-9.
    View in: PubMed
    Score: 0.120
  17. Mejia EM, Ibdah JA, Sparagna GC, Hatch GM. Differential reduction in cardiac and liver monolysocardiolipin acyltransferase-1 and reduction in cardiac and liver tetralinoleoyl-cardiolipin in the a-subunit of trifunctional protein heterozygous knockout mice. Biochem J. 2015 Oct 01; 471(1):123-9.
    View in: PubMed
    Score: 0.116
  18. Chatfield KC, Sparagna GC, Sucharov CC, Miyamoto SD, Grudis JE, Sobus RD, Hijmans J, Stauffer BL. Dysregulation of cardiolipin biosynthesis in pediatric heart failure. J Mol Cell Cardiol. 2014 Sep; 74:251-9.
    View in: PubMed
    Score: 0.107
  19. Baz?n S, Mileykovskaya E, Mallampalli VK, Heacock P, Sparagna GC, Dowhan W. Cardiolipin-dependent reconstitution of respiratory supercomplexes from purified Saccharomyces cerevisiae complexes III and IV. J Biol Chem. 2013 Jan 04; 288(1):401-11.
    View in: PubMed
    Score: 0.096
  20. Taylor WA, Mejia EM, Mitchell RW, Choy PC, Sparagna GC, Hatch GM. Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation. PLoS One. 2012; 7(11):e48628.
    View in: PubMed
    Score: 0.096
  21. Mulligan CM, Sparagna GC, Le CH, De Mooy AB, Routh MA, Holmes MG, Hickson-Bick DL, Zarini S, Murphy RC, Xu FY, Hatch GM, McCune SA, Moore RL, Chicco AJ. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. Cardiovasc Res. 2012 Jun 01; 94(3):460-8.
    View in: PubMed
    Score: 0.092
  22. Saini-Chohan HK, Dakshinamurti S, Taylor WA, Shen GX, Murphy R, Sparagna GC, Hatch GM. Persistent pulmonary hypertension results in reduced tetralinoleoyl-cardiolipin and mitochondrial complex II + III during the development of right ventricular hypertrophy in the neonatal pig heart. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1415-24.
    View in: PubMed
    Score: 0.088
  23. Sabbah HN, Alder NN, Sparagna GC, Bruce JE, Stauffer BL, Chao LH, Pitceathly RDS, Maack C, Marcinek DJ. Contemporary insights into elamipretide's mitochondrial mechanism of action and therapeutic effects. Biomed Pharmacother. 2025 Jun; 187:118056.
    View in: PubMed
    Score: 0.057
  24. Rai AK, Sawasato K, Bennett HC, Kozlova A, Sparagna GC, Bogdanov M, Mitchell AM. Genetic evidence for functional diversification of gram-negative intermembrane phospholipid transporters. PLoS Genet. 2024 Jun; 20(6):e1011335.
    View in: PubMed
    Score: 0.054
  25. Hryc CF, Mallampalli VKPS, Bovshik EI, Azinas S, Fan G, Serysheva II, Sparagna GC, Baker ML, Mileykovskaya E, Dowhan W. Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex. Nat Commun. 2023 05 15; 14(1):2783.
    View in: PubMed
    Score: 0.050
  26. Cole RM, Angelotti A, Sparagna GC, Ni A, Belury MA. Linoleic Acid-Rich Oil Alters Circulating Cardiolipin Species and Fatty Acid Composition in Adults: A Randomized Controlled Trial. Mol Nutr Food Res. 2022 08; 66(15):e2101132.
    View in: PubMed
    Score: 0.047
  27. Chatfield KC, Sparagna GC, Specht KS, Whitcomb LA, Omar AK, Miyamoto SD, Wolfe LM, Chicco AJ. Long-chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy. J Inherit Metab Dis. 2022 01; 45(1):111-124.
    View in: PubMed
    Score: 0.045
  28. Ostrander DB, Sparagna GC, Amoscato AA, McMillin JB, Dowhan W. Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis. J Biol Chem. 2001 Oct 12; 276(41):38061-7.
    View in: PubMed
    Score: 0.044
  29. Cole LK, Agarwal P, Doucette CA, Fonseca M, Xiang B, Sparagna GC, Seshadri N, Vandel M, Dolinsky VW, Hatch GM. Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice. Endocrinology. 2021 07 01; 162(7).
    View in: PubMed
    Score: 0.044
  30. Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. J Biol Chem. 2018 01 12; 293(2):466-483.
    View in: PubMed
    Score: 0.034
  31. Sullivan EM, Fix A, Crouch MJ, Sparagna GC, Zeczycki TN, Brown DA, Shaikh SR. Murine diet-induced obesity remodels cardiac and liver mitochondrial phospholipid acyl chains with differential effects on respiratory enzyme activity. J Nutr Biochem. 2017 07; 45:94-103.
    View in: PubMed
    Score: 0.033
  32. Huang JV, Lu L, Ye S, Bergman BC, Sparagna GC, Sarraf M, Reusch JE, Greyson CR, Schwartz GG. Impaired contractile recovery after low-flow myocardial ischemia in a porcine model of metabolic syndrome. Am J Physiol Heart Circ Physiol. 2013 Mar 15; 304(6):H861-73.
    View in: PubMed
    Score: 0.024
  33. O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC. Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition. J Mol Cell Cardiol. 2009 Dec; 47(6):819-27.
    View in: PubMed
    Score: 0.019
  34. Shah KB, Duda MK, O'Shea KM, Sparagna GC, Chess DJ, Khairallah RJ, Robillard-Frayne I, Xu W, Murphy RC, Des Rosiers C, Stanley WC. The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. Hypertension. 2009 Sep; 54(3):605-11.
    View in: PubMed
    Score: 0.019
  35. Gumpricht E, Devereaux MW, Dahl R, Soden JS, Sparagna GC, Leonard SW, Traber MG, Sokol RJ. Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol. Pediatr Res. 2008 Nov; 64(5):498-504.
    View in: PubMed
    Score: 0.018
  36. Chicco AJ, Sparagna GC, McCune SA, Johnson CA, Murphy RC, Bolden DA, Rees ML, Gardner RT, Moore RL. Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets. Hypertension. 2008 Sep; 52(3):549-55.
    View in: PubMed
    Score: 0.018
  37. Chicco AJ, McCune SA, Emter CA, Sparagna GC, Rees ML, Bolden DA, Marshall KD, Murphy RC, Moore RL. Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats. Hypertension. 2008 Apr; 51(4):1096-102.
    View in: PubMed
    Score: 0.017
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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