 Connection
Natalie Ahn to Phosphorylation
This is a "connection" page, showing publications Natalie Ahn has written about Phosphorylation.
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Connection Strength |
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2.385 |
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Basken J, Stuart SA, Kavran AJ, Lee T, Ebmeier CC, Old WM, Ahn NG. Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells. Mol Cell Proteomics. 2018 04; 17(4):550-564.
Score: 0.436
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Pegram L, Riccardi D, Ahn N. Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2. J Mol Biol. 2023 12 01; 435(23):168309.
Score: 0.163
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Iverson DB, Xiao Y, Jones DN, Eisenmesser EZ, Ahn NG. Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2. Biochemistry. 2020 07 28; 59(29):2698-2706.
Score: 0.130
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Pegram LM, Liddle JC, Xiao Y, Hoh M, Rudolph J, Iverson DB, Vigers GP, Smith D, Zhang H, Wang W, Moffat JG, Ahn NG. Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc Natl Acad Sci U S A. 2019 07 30; 116(31):15463-15468.
Score: 0.122
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Sours KM, Xiao Y, Ahn NG. Extracellular-regulated kinase 2 is activated by the enhancement of hinge flexibility. J Mol Biol. 2014 May 01; 426(9):1925-35.
Score: 0.084
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Xiao Y, Lee T, Latham MP, Warner LR, Tanimoto A, Pardi A, Ahn NG. Phosphorylation releases constraints to domain motion in ERK2. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2506-11.
Score: 0.083
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Ahn NG. PORE-ing over ERK substrates. Nat Struct Mol Biol. 2009 Oct; 16(10):1004-5.
Score: 0.062
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Old WM, Shabb JB, Houel S, Wang H, Couts KL, Yen CY, Litman ES, Croy CH, Meyer-Arendt K, Miranda JG, Brown RA, Witze ES, Schweppe RE, Resing KA, Ahn NG. Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol Cell. 2009 Apr 10; 34(1):115-31.
Score: 0.060
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Sours KM, Kwok SC, Rachidi T, Lee T, Ring A, Hoofnagle AN, Resing KA, Ahn NG. Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase. J Mol Biol. 2008 Jun 20; 379(5):1075-93.
Score: 0.056
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Witze ES, Old WM, Resing KA, Ahn NG. Mapping protein post-translational modifications with mass spectrometry. Nat Methods. 2007 Oct; 4(10):798-806.
Score: 0.054
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Emrick MA, Lee T, Starkey PJ, Mumby MC, Resing KA, Ahn NG. The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18101-6.
Score: 0.051
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Roberts EC, Hammond K, Traish AM, Resing KA, Ahn NG. Identification of G2/M targets for the MAP kinase pathway by functional proteomics. Proteomics. 2006 Aug; 6(16):4541-53.
Score: 0.050
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Kabuyama Y, Langer SJ, Polvinen K, Homma Y, Resing KA, Ahn NG. Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling. Mol Cell Proteomics. 2006 Aug; 5(8):1359-67.
Score: 0.049
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Lee T, Hoofnagle AN, Resing KA, Ahn NG. Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation. J Mol Biol. 2005 Oct 28; 353(3):600-12.
Score: 0.046
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Hoofnagle AN, Stoner JW, Lee T, Eaton SS, Ahn NG. Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR. Biophys J. 2004 Jan; 86(1 Pt 1):395-403.
Score: 0.041
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Haydon CE, Eyers PA, Aveline-Wolf LD, Resing KA, Maller JL, Ahn NG. Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography. Mol Cell Proteomics. 2003 Oct; 2(10):1055-67.
Score: 0.040
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Galasinski SC, Resing KA, Goodrich JA, Ahn NG. Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions. J Biol Chem. 2002 May 31; 277(22):19618-26.
Score: 0.037
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Galasinski SC, Louie DF, Gloor KK, Resing KA, Ahn NG. Global regulation of post-translational modifications on core histones. J Biol Chem. 2002 Jan 25; 277(4):2579-88.
Score: 0.036
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Ahn NG, Resing KA. Toward the phosphoproteome. Nat Biotechnol. 2001 Apr; 19(4):317-8.
Score: 0.034
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Hoofnagle AN, Resing KA, Goldsmith EJ, Ahn NG. Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):956-61.
Score: 0.034
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Ahn NG, Nahreini TS, Tolwinski NS, Resing KA. Pharmacologic inhibitors of MKK1 and MKK2. Methods Enzymol. 2001; 332:417-31.
Score: 0.034
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Lewis TS, Hunt JB, Aveline LD, Jonscher KR, Louie DF, Yeh JM, Nahreini TS, Resing KA, Ahn NG. Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry. Mol Cell. 2000 Dec; 6(6):1343-54.
Score: 0.033
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Louie DF, Gloor KK, Galasinski SC, Resing KA, Ahn NG. Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry. Protein Sci. 2000 Jan; 9(1):170-9.
Score: 0.031
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Lopez ED, Burastero O, Arcon JP, Defelipe LA, Ahn NG, Marti MA, Turjanski AG. Kinase Activation by Small Conformational Changes. J Chem Inf Model. 2020 02 24; 60(2):821-832.
Score: 0.031
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Shapiro PS, Whalen AM, Tolwinski NS, Wilsbacher J, Froelich-Ammon SJ, Garcia M, Osheroff N, Ahn NG. Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation. Mol Cell Biol. 1999 May; 19(5):3551-60.
Score: 0.030
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Tolwinski NS, Shapiro PS, Goueli S, Ahn NG. Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression. Requirement for phosphorylation at the activation lip and signaling downstream of MKK. J Biol Chem. 1999 Mar 05; 274(10):6168-74.
Score: 0.030
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Shapiro PS, Ahn NG. Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1). J Biol Chem. 1998 Jan 16; 273(3):1788-93.
Score: 0.027
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Resing KA, Ahn NG. Protein phosphorylation analysis by electrospray ionization-mass spectrometry. Methods Enzymol. 1997; 283:29-44.
Score: 0.025
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Goshen-Lago T, Goldberg-Carp A, Melamed D, Darlyuk-Saadon I, Bai C, Ahn NG, Admon A, Engelberg D. Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation. Mol Biol Cell. 2016 09 01; 27(17):2771-83.
Score: 0.025
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Beenstock J, Melamed D, Mooshayef N, Mordechay D, Garfinkel BP, Ahn NG, Admon A, Engelberg D. p38? Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261. Mol Cell Biol. 2016 05 15; 36(10):1540-54.
Score: 0.024
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Smorodinsky-Atias K, Goshen-Lago T, Goldberg-Carp A, Melamed D, Shir A, Mooshayef N, Beenstock J, Karamansha Y, Darlyuk-Saadon I, Livnah O, Ahn NG, Admon A, Engelberg D. Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation. Mol Biol Cell. 2016 Mar 15; 27(6):1026-39.
Score: 0.024
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Brown R, Stuart SA, Stuart SS, Houel S, Ahn NG, Old WM. Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss during Collision Induced Dissociation. J Am Soc Mass Spectrom. 2015 Jul; 26(7):1128-42.
Score: 0.023
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Resing KA, Mansour SJ, Hermann AS, Johnson RS, Candia JM, Fukasawa K, Vande Woude GF, Ahn NG. Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS. Biochemistry. 1995 Feb 28; 34(8):2610-20.
Score: 0.022
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Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science. 1994 Aug 12; 265(5174):966-70.
Score: 0.022
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Mansour SJ, Resing KA, Candi JM, Hermann AS, Gloor JW, Herskind KR, Wartmann M, Davis RJ, Ahn NG. Mitogen-activated protein (MAP) kinase phosphorylation of MAP kinase kinase: determination of phosphorylation sites by mass spectrometry and site-directed mutagenesis. J Biochem. 1994 Aug; 116(2):304-14.
Score: 0.022
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Beenstock J, Ben-Yehuda S, Melamed D, Admon A, Livnah O, Ahn NG, Engelberg D. The p38? mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the a-G helix and MAPK insert. J Biol Chem. 2014 Aug 22; 289(34):23546-56.
Score: 0.021
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Ahn NG, Campbell JS, Seger R, Jensen AL, Graves LM, Krebs EG. Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5143-7.
Score: 0.020
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Ahn NG, Seger R, Krebs EG. The mitogen-activated protein kinase activator. Curr Opin Cell Biol. 1992 Dec; 4(6):992-9.
Score: 0.019
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Ahn NG, Robbins DJ, Haycock JW, Seger R, Cobb MH, Krebs EG. Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin. J Neurochem. 1992 Jul; 59(1):147-56.
Score: 0.019
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Ahn NG, Seger R, Bratlien RL, Krebs EG. Growth factor-stimulated phosphorylation cascades: activation of growth factor-stimulated MAP kinase. Ciba Found Symp. 1992; 164:113-26; discussion 126-31.
Score: 0.018
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Ahn NG, Krebs EG. Evidence for an epidermal growth factor-stimulated protein kinase cascade in Swiss 3T3 cells. Activation of serine peptide kinase activity by myelin basic protein kinases in vitro. J Biol Chem. 1990 Jul 15; 265(20):11495-501.
Score: 0.016
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Wang W, Yang Y, Gao Y, Xu Q, Wang F, Zhu S, Old W, Resing K, Ahn N, Lei M, Liu X. Structural and mechanistic insights into Mps1 kinase activation. J Cell Mol Med. 2009 Aug; 13(8B):1679-1694.
Score: 0.015
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Xu Q, Zhu S, Wang W, Zhang X, Old W, Ahn N, Liu X. Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. Mol Biol Cell. 2009 Jan; 20(1):10-20.
Score: 0.014
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Levin-Salomon V, Kogan K, Ahn NG, Livnah O, Engelberg D. Isolation of intrinsically active (MEK-independent) variants of the ERK family of mitogen-activated protein (MAP) kinases. J Biol Chem. 2008 Dec 12; 283(50):34500-10.
Score: 0.014
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Mattison CP, Old WM, Steiner E, Huneycutt BJ, Resing KA, Ahn NG, Winey M. Mps1 activation loop autophosphorylation enhances kinase activity. J Biol Chem. 2007 Oct 19; 282(42):30553-61.
Score: 0.013
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Jaspersen SL, Huneycutt BJ, Giddings TH, Resing KA, Ahn NG, Winey M. Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1. Dev Cell. 2004 Aug; 7(2):263-74.
Score: 0.011
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Vaish NK, Dong F, Andrews L, Schweppe RE, Ahn NG, Blatt L, Seiwert SD. Monitoring post-translational modification of proteins with allosteric ribozymes. Nat Biotechnol. 2002 Aug; 20(8):810-5.
Score: 0.009
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Thulin CD, Savage JR, McLaughlin JN, Truscott SM, Old WM, Ahn NG, Resing KA, Hamm HE, Bitensky MW, Willardson BM. Modulation of the G protein regulator phosducin by Ca2+/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding. J Biol Chem. 2001 Jun 29; 276(26):23805-15.
Score: 0.009
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Friedman DB, Kern JW, Huneycutt BJ, Vinh DB, Crawford DK, Steiner E, Scheiltz D, Yates J, Resing KA, Ahn NG, Winey M, Davis TN. Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem. 2001 May 25; 276(21):17958-67.
Score: 0.009
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Seiwert SD, Stines Nahreini T, Aigner S, Ahn NG, Uhlenbeck OC. RNA aptamers as pathway-specific MAP kinase inhibitors. Chem Biol. 2000 Nov; 7(11):833-43.
Score: 0.008
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Prowse CN, Hagopian JC, Cobb MH, Ahn NG, Lew J. Catalytic reaction pathway for the mitogen-activated protein kinase ERK2. Biochemistry. 2000 May 23; 39(20):6258-66.
Score: 0.008
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Boeshans KM, Resing KA, Hunt JB, Ahn NG, Shabb JB. Structural characterization of the membrane-associated regulatory subunit of type I cAMP-dependent protein kinase by mass spectrometry: identification of Ser81 as the in vivo phosphorylation site of RIalpha. Protein Sci. 1999 Jul; 8(7):1515-22.
Score: 0.008
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Biggs JR, Ahn NG, Kraft AS. Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein. Cell Growth Differ. 1998 Aug; 9(8):667-76.
Score: 0.007
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Amin ND, Ahn NG, Jaffe H, Winters CA, Grant P, Pant HC. Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M. J Neurosci. 1998 Jun 01; 18(11):4008-21.
Score: 0.007
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Duesbery NS, Webb CP, Leppla SH, Gordon VM, Klimpel KR, Copeland TD, Ahn NG, Oskarsson MK, Fukasawa K, Paull KD, Vande Woude GF. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science. 1998 May 01; 280(5364):734-7.
Score: 0.007
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Frost JA, Steen H, Shapiro P, Lewis T, Ahn N, Shaw PE, Cobb MH. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J. 1997 Nov 03; 16(21):6426-38.
Score: 0.007
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Whalen SG, Marcellus RC, Whalen A, Ahn NG, Ricciardi RP, Branton PE. Phosphorylation within the transactivation domain of adenovirus E1A protein by mitogen-activated protein kinase regulates expression of early region 4. J Virol. 1997 May; 71(5):3545-53.
Score: 0.007
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Robinson MJ, Cheng M, Khokhlatchev A, Ebert D, Ahn N, Guan KL, Stein B, Goldsmith E, Cobb MH. Contributions of the mitogen-activated protein (MAP) kinase backbone and phosphorylation loop to MEK specificity. J Biol Chem. 1996 Nov 22; 271(47):29734-9.
Score: 0.006
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al-Alawi N, Rose DW, Buckmaster C, Ahn N, Rapp U, Meinkoth J, Feramisco JR. Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade. Mol Cell Biol. 1995 Mar; 15(3):1162-8.
Score: 0.006
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Markowitz RB, Hermann AS, Taylor DF, He L, Anthony-Cahill S, Ahn NG, Dynan WS. Phosphorylation of the C-terminal domain of RNA polymerase II by the extracellular-signal-regulated protein kinase ERK2. Biochem Biophys Res Commun. 1995 Feb 27; 207(3):1051-7.
Score: 0.006
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Gause KC, Homma MK, Licciardi KA, Seger R, Ahn NG, Peterson MJ, Krebs EG, Meier KE. Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells. J Biol Chem. 1993 Aug 05; 268(22):16124-9.
Score: 0.005
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Genot EM, Meier KE, Licciardi KA, Ahn NG, Uittenbogaart CH, Wietzerbin J, Clark EA, Valentine MA. Phosphorylation of CD20 in cells from a hairy cell leukemia cell line. Evidence for involvement of calcium/calmodulin-dependent protein kinase II. J Immunol. 1993 Jul 01; 151(1):71-82.
Score: 0.005
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Posada J, Yew N, Ahn NG, Vande Woude GF, Cooper JA. Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Mol Cell Biol. 1993 Apr; 13(4):2546-53.
Score: 0.005
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Seger R, Ahn NG, Posada J, Munar ES, Jensen AM, Cooper JA, Cobb MH, Krebs EG. Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. J Biol Chem. 1992 Jul 15; 267(20):14373-81.
Score: 0.005
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Haycock JW, Ahn NG, Cobb MH, Krebs EG. ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2365-9.
Score: 0.005
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Seger R, Ahn NG, Boulton TG, Yancopoulos GD, Panayotatos N, Radziejewska E, Ericsson L, Bratlien RL, Cobb MH, Krebs EG. Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6142-6.
Score: 0.004
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Weiel JE, Ahn NG, Seger R, Krebs EG. Communication between protein tyrosine and protein serine/threonine phosphorylation. Adv Second Messenger Phosphoprotein Res. 1990; 24:182-95.
Score: 0.004
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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