 Connection
Natalie Ahn to Mitogen-Activated Protein Kinase 1
This is a "connection" page, showing publications Natalie Ahn has written about Mitogen-Activated Protein Kinase 1.
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4.801 |
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Pegram L, Riccardi D, Ahn N. Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2. J Mol Biol. 2023 12 01; 435(23):168309.
Score: 0.804
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Iverson DB, Xiao Y, Jones DN, Eisenmesser EZ, Ahn NG. Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2. Biochemistry. 2020 07 28; 59(29):2698-2706.
Score: 0.643
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Rudolph J, Xiao Y, Pardi A, Ahn NG. Slow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitors. Biochemistry. 2015 Jan 13; 54(1):22-31.
Score: 0.436
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Sours KM, Xiao Y, Ahn NG. Extracellular-regulated kinase 2 is activated by the enhancement of hinge flexibility. J Mol Biol. 2014 May 01; 426(9):1925-35.
Score: 0.412
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Xiao Y, Lee T, Latham MP, Warner LR, Tanimoto A, Pardi A, Ahn NG. Phosphorylation releases constraints to domain motion in ERK2. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2506-11.
Score: 0.411
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Emrick MA, Lee T, Starkey PJ, Mumby MC, Resing KA, Ahn NG. The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18101-6.
Score: 0.250
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Schweppe RE, Cheung TH, Ahn NG. Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses. J Biol Chem. 2006 Jul 28; 281(30):20993-21003.
Score: 0.242
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Lee T, Hoofnagle AN, Resing KA, Ahn NG. Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation. J Mol Biol. 2005 Oct 28; 353(3):600-12.
Score: 0.230
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Hoofnagle AN, Stoner JW, Lee T, Eaton SS, Ahn NG. Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR. Biophys J. 2004 Jan; 86(1 Pt 1):395-403.
Score: 0.204
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Emrick MA, Hoofnagle AN, Miller AS, Ten Eyck LF, Ahn NG. Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations. J Biol Chem. 2001 Dec 07; 276(49):46469-79.
Score: 0.175
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Hoofnagle AN, Resing KA, Goldsmith EJ, Ahn NG. Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):956-61.
Score: 0.167
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Lopez ED, Burastero O, Arcon JP, Defelipe LA, Ahn NG, Marti MA, Turjanski AG. Kinase Activation by Small Conformational Changes. J Chem Inf Model. 2020 02 24; 60(2):821-832.
Score: 0.154
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Xiao Y, Warner LR, Latham MP, Ahn NG, Pardi A. Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2. Biochemistry. 2015 Jul 21; 54(28):4307-19.
Score: 0.114
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Sours KM, Ahn NG. Analysis of MAP kinases by hydrogen exchange mass spectrometry. Methods Mol Biol. 2010; 661:239-55.
Score: 0.077
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Sours KM, Kwok SC, Rachidi T, Lee T, Ring A, Hoofnagle AN, Resing KA, Ahn NG. Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase. J Mol Biol. 2008 Jun 20; 379(5):1075-93.
Score: 0.069
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Hoofnagle AN, Resing KA, Ahn NG. Practical methods for deuterium exchange/mass spectrometry. Methods Mol Biol. 2004; 250:283-98.
Score: 0.051
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Vaish NK, Dong F, Andrews L, Schweppe RE, Ahn NG, Blatt L, Seiwert SD. Monitoring post-translational modification of proteins with allosteric ribozymes. Nat Biotechnol. 2002 Aug; 20(8):810-5.
Score: 0.046
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Jesch SA, Lewis TS, Ahn NG, Linstedt AD. Mitotic phosphorylation of Golgi reassembly stacking protein 55 by mitogen-activated protein kinase ERK2. Mol Biol Cell. 2001 Jun; 12(6):1811-7.
Score: 0.043
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Seiwert SD, Stines Nahreini T, Aigner S, Ahn NG, Uhlenbeck OC. RNA aptamers as pathway-specific MAP kinase inhibitors. Chem Biol. 2000 Nov; 7(11):833-43.
Score: 0.041
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Prowse CN, Hagopian JC, Cobb MH, Ahn NG, Lew J. Catalytic reaction pathway for the mitogen-activated protein kinase ERK2. Biochemistry. 2000 May 23; 39(20):6258-66.
Score: 0.040
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Resing KA, Hoofnagle AN, Ahn NG. Modeling deuterium exchange behavior of ERK2 using pepsin mapping to probe secondary structure. J Am Soc Mass Spectrom. 1999 Aug; 10(8):685-702.
Score: 0.038
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Shapiro PS, Whalen AM, Tolwinski NS, Wilsbacher J, Froelich-Ammon SJ, Garcia M, Osheroff N, Ahn NG. Extracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation. Mol Cell Biol. 1999 May; 19(5):3551-60.
Score: 0.037
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Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science. 1994 Aug 12; 265(5174):966-70.
Score: 0.027
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Ahn NG, Robbins DJ, Haycock JW, Seger R, Cobb MH, Krebs EG. Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin. J Neurochem. 1992 Jul; 59(1):147-56.
Score: 0.023
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Rak J, Mitsuhashi Y, Sheehan C, Tamir A, Viloria-Petit A, Filmus J, Mansour SJ, Ahn NG, Kerbel RS. Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts. Cancer Res. 2000 Jan 15; 60(2):490-8.
Score: 0.010
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Biggs JR, Ahn NG, Kraft AS. Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein. Cell Growth Differ. 1998 Aug; 9(8):667-76.
Score: 0.009
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Amin ND, Ahn NG, Jaffe H, Winters CA, Grant P, Pant HC. Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M. J Neurosci. 1998 Jun 01; 18(11):4008-21.
Score: 0.009
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Frost JA, Steen H, Shapiro P, Lewis T, Ahn N, Shaw PE, Cobb MH. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J. 1997 Nov 03; 16(21):6426-38.
Score: 0.008
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Thorburn J, Carlson M, Mansour SJ, Chien KR, Ahn NG, Thorburn A. Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase. Mol Biol Cell. 1995 Nov; 6(11):1479-90.
Score: 0.007
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Markowitz RB, Hermann AS, Taylor DF, He L, Anthony-Cahill S, Ahn NG, Dynan WS. Phosphorylation of the C-terminal domain of RNA polymerase II by the extracellular-signal-regulated protein kinase ERK2. Biochem Biophys Res Commun. 1995 Feb 27; 207(3):1051-7.
Score: 0.007
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Gause KC, Homma MK, Licciardi KA, Seger R, Ahn NG, Peterson MJ, Krebs EG, Meier KE. Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells. J Biol Chem. 1993 Aug 05; 268(22):16124-9.
Score: 0.006
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Haycock JW, Ahn NG, Cobb MH, Krebs EG. ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2365-9.
Score: 0.006
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Seger R, Ahn NG, Boulton TG, Yancopoulos GD, Panayotatos N, Radziejewska E, Ericsson L, Bratlien RL, Cobb MH, Krebs EG. Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6142-6.
Score: 0.005
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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