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Connection

Rubin Tuder to Hypertension, Pulmonary

This is a "connection" page, showing publications Rubin Tuder has written about Hypertension, Pulmonary.

 
Connection Strength
 
 
 
11.888
 
  1. Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM. Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L355-L371.
    View in: PubMed
    Score: 0.379
  2. Tuder RM, Stenmark KR. Perspective: pathobiological paradigms in pulmonary hypertension, time for reappraisal. Am J Physiol Lung Cell Mol Physiol. 2020 06 01; 318(6):L1131-L1137.
    View in: PubMed
    Score: 0.324
  3. Tuder RM, Cool CD. Pulmonary Arteries and Microcirculation in?COPD With Pulmonary Hypertension: Bystander or Culprit? Chest. 2019 07; 156(1):4-6.
    View in: PubMed
    Score: 0.308
  4. Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2018 10; 59(4):479-489.
    View in: PubMed
    Score: 0.292
  5. Stenmark KR, Tuder RM. Peroxisome Proliferator-activated Receptor ? and Mitochondria: Drivers or Passengers on the Road to Pulmonary Hypertension? Am J Respir Cell Mol Biol. 2018 05; 58(5):555-557.
    View in: PubMed
    Score: 0.284
  6. Stenmark KR, Frid MG, Graham BB, Tuder RM. Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension. Cardiovasc Res. 2018 03 15; 114(4):551-564.
    View in: PubMed
    Score: 0.281
  7. Graham BB, Koyanagi D, Kandasamy B, Tuder RM. Right Ventricle Vasculature in Human Pulmonary Hypertension Assessed by Stereology. Am J Respir Crit Care Med. 2017 10 15; 196(8):1075-1077.
    View in: PubMed
    Score: 0.274
  8. Tuder RM. Pulmonary vascular remodeling in pulmonary hypertension. Cell Tissue Res. 2017 03; 367(3):643-649.
    View in: PubMed
    Score: 0.259
  9. Stenmark KR, Krafsur GM, Tuder RM. Pulmonary Veno-occlusive Disease and Pulmonary Hypertension in Dogs: Striking Similarities to the Human Condition. Vet Pathol. 2016 07; 53(4):707-10.
    View in: PubMed
    Score: 0.250
  10. Graham BB, Kumar R, Mickael C, Sanders L, Gebreab L, Huber KM, Perez M, Smith-Jones P, Serkova NJ, Tuder RM. Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 01; 309(5):L435-40.
    View in: PubMed
    Score: 0.233
  11. Robinson JC, Graham BB, Rouault TC, Tuder RM. The crossroads of iron with hypoxia and cellular metabolism. Implications in the pathobiology of pulmonary hypertension. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):721-9.
    View in: PubMed
    Score: 0.224
  12. Tuder RM. How do we measure pathology in PAH (lung and RV) and what does it tell us about the disease. Drug Discov Today. 2014 Aug; 19(8):1257-63.
    View in: PubMed
    Score: 0.216
  13. Tuder RM, Robinson JC, Graham BB. Fat and cardiotoxicity in hereditary pulmonary hypertension. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):247-9.
    View in: PubMed
    Score: 0.212
  14. Tuder RM, Archer SL, Dorfm?ller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D4-12.
    View in: PubMed
    Score: 0.210
  15. Graham BB, Chabon J, Kumar R, Kolosionek E, Gebreab L, Debella E, Edwards M, Diener K, Shade T, Bifeng G, Bandeira A, Butrous G, Jones K, Geraci M, Tuder RM. Protective role of IL-6 in vascular remodeling in Schistosoma pulmonary hypertension. Am J Respir Cell Mol Biol. 2013 Dec; 49(6):951-9.
    View in: PubMed
    Score: 0.209
  16. Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB. Pathology of pulmonary hypertension. Clin Chest Med. 2013 Dec; 34(4):639-50.
    View in: PubMed
    Score: 0.207
  17. Hunt JM, Bethea B, Liu X, Gandjeva A, Mammen PP, Stacher E, Gandjeva MR, Parish E, Perez M, Smith L, Graham BB, Kuebler WM, Tuder RM. Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15; 305(10):L725-36.
    View in: PubMed
    Score: 0.206
  18. Graham BB, Chabon J, Gebreab L, Poole J, Debella E, Davis L, Tanaka T, Sanders L, Dropcho N, Bandeira A, Vandivier RW, Champion HC, Butrous G, Wang XJ, Wynn TA, Tuder RM. Transforming growth factor-? signaling promotes pulmonary hypertension caused by Schistosoma mansoni. Circulation. 2013 Sep 17; 128(12):1354-64.
    View in: PubMed
    Score: 0.205
  19. Stacher E, Graham BB, Hunt JM, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM. Modern age pathology of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Aug 01; 186(3):261-72.
    View in: PubMed
    Score: 0.189
  20. Tuder RM, Davis LA, Graham BB. Targeting energetic metabolism: a new frontier in the pathogenesis and treatment of pulmonary hypertension. Am J Respir Crit Care Med. 2012 Feb 01; 185(3):260-6.
    View in: PubMed
    Score: 0.181
  21. Graham BB, Mentink-Kane MM, El-Haddad H, Purnell S, Zhang L, Zaiman A, Redente EF, Riches DW, Hassoun PM, Bandeira A, Champion HC, Butrous G, Wynn TA, Tuder RM. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Am J Pathol. 2010 Sep; 177(3):1549-61.
    View in: PubMed
    Score: 0.166
  22. Graham BB, Bandeira AP, Morrell NW, Butrous G, Tuder RM. Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective. Chest. 2010 Jun; 137(6 Suppl):20S-29S.
    View in: PubMed
    Score: 0.164
  23. Fijalkowska I, Xu W, Comhair SA, Janocha AJ, Mavrakis LA, Krishnamachary B, Zhen L, Mao T, Richter A, Erzurum SC, Tuder RM. Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells. Am J Pathol. 2010 Mar; 176(3):1130-8.
    View in: PubMed
    Score: 0.160
  24. Geraci MW, Bull TM, Tuder RM. Genomics of pulmonary arterial hypertension: implications for therapy. Heart Fail Clin. 2010 Jan; 6(1):101-14.
    View in: PubMed
    Score: 0.159
  25. Graham BB, Tuder RM. [Pathogenesis of pulmonary hypertension]. Zhonghua Yi Xue Za Zhi. 2009 Aug 11; 89(30):2091-3.
    View in: PubMed
    Score: 0.155
  26. Tuder RM. Pathology of pulmonary arterial hypertension. Semin Respir Crit Care Med. 2009 Aug; 30(4):376-85.
    View in: PubMed
    Score: 0.155
  27. Tuder RM, Abman SH, Braun T, Capron F, Stevens T, Thistlethwaite PA, Haworth SG. Development and pathology of pulmonary hypertension. J Am Coll Cardiol. 2009 Jun 30; 54(1 Suppl):S3-S9.
    View in: PubMed
    Score: 0.154
  28. Asosingh K, Erzurum SC, Yoder MC, Tuder RM. Letter by asosingh et Al regarding article, "circulating endothelial progenitor cells in patients with eisenmenger syndrome and idiopathic pulmonary arterial hypertension". Circulation. 2009 Mar 10; 119(9):e230; author reply e231.
    View in: PubMed
    Score: 0.151
  29. Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. Am J Respir Crit Care Med. 2008 Apr 15; 177(8):896-905.
    View in: PubMed
    Score: 0.139
  30. Tuder RM, Marecki JC, Richter A, Fijalkowska I, Flores S. Pathology of pulmonary hypertension. Clin Chest Med. 2007 Mar; 28(1):23-42, vii.
    View in: PubMed
    Score: 0.131
  31. Nathan SD, Noble PW, Tuder RM. Idiopathic pulmonary fibrosis and pulmonary hypertension: connecting the dots. Am J Respir Crit Care Med. 2007 May 01; 175(9):875-80.
    View in: PubMed
    Score: 0.130
  32. Tuder RM. [Pulmonary hypertension: characterization based on the experience of reference centers. ]. Rev Assoc Med Bras (1992). 2006 May-Jun; 52(3):127-9.
    View in: PubMed
    Score: 0.125
  33. Zaiman A, Fijalkowska I, Hassoun PM, Tuder RM. One hundred years of research in the pathogenesis of pulmonary hypertension. Am J Respir Cell Mol Biol. 2005 Nov; 33(5):425-31.
    View in: PubMed
    Score: 0.119
  34. Richter A, Yeager ME, Zaiman A, Cool CD, Voelkel NF, Tuder RM. Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2004 Dec 15; 170(12):1340-8.
    View in: PubMed
    Score: 0.110
  35. Pietra GG, Capron F, Stewart S, Leone O, Humbert M, Robbins IM, Reid LM, Tuder RM. Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol. 2004 Jun 16; 43(12 Suppl S):25S-32S.
    View in: PubMed
    Score: 0.109
  36. Horton MR, Tuder RM. Primary pulmonary arterial hypertension presenting as diffuse micronodules on CT. Crit Rev Comput Tomogr. 2004; 45(5-6):335-41.
    View in: PubMed
    Score: 0.105
  37. Li M, Plecit?-Hlavat? L, Dobrinskikh E, McKeon BA, Gandjeva A, Riddle S, Laux A, Prasad RR, Kumar S, Tuder RM, Zhang H, Hu CJ, Stenmark KR. SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2023 11; 69(5):570-583.
    View in: PubMed
    Score: 0.104
  38. Hu CJ, Laux A, Gandjeva A, Wang L, Li M, Brown RD, Riddle S, Kheyfets VO, Tuder RM, Zhang H, Stenmark KR. The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2023 07; 69(1):73-86.
    View in: PubMed
    Score: 0.102
  39. Kumar R, Lee MH, Kassa B, Fonseca Balladares DC, Mickael C, Sanders L, Andruska A, Kumar M, Spiekerkoetter E, Bandeira A, Stenmark KR, Tuder RM, Graham BB. Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension. Clin Sci (Lond). 2023 04 26; 137(8):617-631.
    View in: PubMed
    Score: 0.100
  40. Gu S, Goel K, Forbes LM, Kheyfets VO, Yu YA, Tuder RM, Stenmark KR. Tensions in Taxonomies: Current Understanding and Future Directions in the Pathobiologic Basis and Treatment of Group 1 and Group 3 Pulmonary Hypertension. Compr Physiol. 2023 01 30; 13(1):4295-4319.
    View in: PubMed
    Score: 0.099
  41. Galkin A, Sitapara R, Clemons B, Garcia E, Kennedy M, Guimond D, Carter LL, Douthitt A, Osterhout R, Gandjeva A, Slee D, Salter-Cid L, Tuder RM, Zisman LS. Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension. Eur Respir J. 2022 12; 60(6).
    View in: PubMed
    Score: 0.098
  42. Tuder RM, Voelkel NF. Angiogenesis and pulmonary hypertension: a unique process in a unique disease. Antioxid Redox Signal. 2002 Oct; 4(5):833-43.
    View in: PubMed
    Score: 0.096
  43. Voelkel NF, Cool C, Taraceviene-Stewart L, Geraci MW, Yeager M, Bull T, Kasper M, Tuder RM. Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Crit Care Med. 2002 May; 30(5 Suppl):S251-6.
    View in: PubMed
    Score: 0.094
  44. Kassa B, Lee MH, Kumar R, Mickael C, Sanders L, Tuder RM, Mentink-Kane M, Graham BB. Experimental Schistosoma japonicum-induced pulmonary hypertension. PLoS Negl Trop Dis. 2022 04; 16(4):e0010343.
    View in: PubMed
    Score: 0.093
  45. Yeager ME, Golpon HA, Voelkel NF, Tuder RM. Microsatellite mutational analysis of endothelial cells within plexiform lesions from patients with familial, pediatric, and sporadic pulmonary hypertension. Chest. 2002 Mar; 121(3 Suppl):61S.
    View in: PubMed
    Score: 0.093
  46. Tuder RM, Zaiman AL. Prostacyclin analogs as the brakes for pulmonary artery smooth muscle cell proliferation: is it sufficient to treat severe pulmonary hypertension? Am J Respir Cell Mol Biol. 2002 Feb; 26(2):171-4.
    View in: PubMed
    Score: 0.092
  47. Kassa B, Kumar R, Mickael C, Sanders L, Vohwinkel C, Lee MH, Gu S, Poth JM, Stenmark KR, Zhao YY, Tuder RM, Graham BB. Endothelial cell PHD2-HIF1a-PFKFB3 contributes to right ventricle vascular adaptation in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2021 10 01; 321(4):L675-L685.
    View in: PubMed
    Score: 0.089
  48. Tuder RM, Voelkel NF. Plexiform lesion in severe pulmonary hypertension: association with glomeruloid lesion. Am J Pathol. 2001 Jul; 159(1):382-3.
    View in: PubMed
    Score: 0.088
  49. Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J. 2001 Feb; 15(2):427-38.
    View in: PubMed
    Score: 0.086
  50. Yeager ME, Halley GR, Golpon HA, Voelkel NF, Tuder RM. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension. Circ Res. 2001 Jan 19; 88(1):E2-E11.
    View in: PubMed
    Score: 0.086
  51. Kumar R, Mickael C, Kassa B, Sanders L, Hernandez-Saavedra D, Koyanagi DE, Kumar S, Pugliese SC, Thomas S, McClendon J, Maloney JP, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension. Cardiovasc Res. 2020 10 01; 116(12):2021-2030.
    View in: PubMed
    Score: 0.084
  52. Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR. Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239.
    View in: PubMed
    Score: 0.080
  53. Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Sci Rep. 2020 01 15; 10(1):413.
    View in: PubMed
    Score: 0.080
  54. Hashimoto R, Lanier GM, Dhagia V, Joshi SR, Jordan A, Waddell I, Tuder R, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA. Pluripotent hematopoietic stem cells augment a-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2020 02 01; 318(2):L386-L401.
    View in: PubMed
    Score: 0.080
  55. Voelkel NF, Tuder RM. Severe pulmonary hypertensive diseases: a perspective. Eur Respir J. 1999 Dec; 14(6):1246-50.
    View in: PubMed
    Score: 0.079
  56. Cool CD, Stewart JS, Werahera P, Miller GJ, Williams RL, Voelkel NF, Tuder RM. Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth. Am J Pathol. 1999 Aug; 155(2):411-9.
    View in: PubMed
    Score: 0.077
  57. Kumar R, Mickael C, Kassa B, Sanders L, Koyanagi D, Hernandez-Saavedra D, Freeman S, Morales-Cano D, Cogolludo A, McKee AS, Fontenot AP, Butrous G, Tuder RM, Graham BB. Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma-Pulmonary Hypertension. J Am Heart Assoc. 2019 08 06; 8(15):e013111.
    View in: PubMed
    Score: 0.077
  58. Mickael C, Kumar R, Hernandez-Saavedra D, Kassa B, Sanders L, Koyanagi D, Gu S, Lee MH, Tuder RM, Graham BB. IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 07; 61(1):123-126.
    View in: PubMed
    Score: 0.077
  59. Tuder RM, Cool CD, Geraci MW, Wang J, Abman SH, Wright L, Badesch D, Voelkel NF. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am J Respir Crit Care Med. 1999 Jun; 159(6):1925-32.
    View in: PubMed
    Score: 0.077
  60. Tuder RM, Radisavljevic Z, Shroyer KR, Polak JM, Voelkel NF. Monoclonal endothelial cells in appetite suppressant-associated pulmonary hypertension. Am J Respir Crit Care Med. 1998 Dec; 158(6):1999-2001.
    View in: PubMed
    Score: 0.074
  61. Voelkel NF, Cool C, Lee SD, Wright L, Geraci MW, Tuder RM. Primary pulmonary hypertension between inflammation and cancer. Chest. 1998 Sep; 114(3 Suppl):225S-230S.
    View in: PubMed
    Score: 0.073
  62. Tuder RM, Voelkel NF. Pulmonary hypertension and inflammation. J Lab Clin Med. 1998 Jul; 132(1):16-24.
    View in: PubMed
    Score: 0.072
  63. Tuder RM, Lee SD, Cool CC. Histopathology of pulmonary hypertension. Chest. 1998 Jul; 114(1 Suppl):1S-6S.
    View in: PubMed
    Score: 0.072
  64. Zamanian RT, Hedlin H, Greuenwald P, Wilson DM, Segal JI, Jorden M, Kudelko K, Liu J, Hsi A, Rupp A, Sweatt AJ, Tuder R, Berry GJ, Rabinovitch M, Doyle RL, de Jesus Perez V, Kawut SM. Features and Outcomes of Methamphetamine-associated Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2018 03 15; 197(6):788-800.
    View in: PubMed
    Score: 0.070
  65. Lee SD, Shroyer KR, Markham NE, Cool CD, Voelkel NF, Tuder RM. Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. J Clin Invest. 1998 Mar 01; 101(5):927-34.
    View in: PubMed
    Score: 0.070
  66. Voelkel NF, Tuder RM. Cellular and molecular biology of vascular smooth muscle cells in pulmonary hypertension. Pulm Pharmacol Ther. 1997 Oct-Dec; 10(5-6):231-41.
    View in: PubMed
    Score: 0.068
  67. Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. TGF-? activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nat Commun. 2017 05 30; 8:15494.
    View in: PubMed
    Score: 0.067
  68. Cool CD, Kennedy D, Voelkel NF, Tuder RM. Pathogenesis and evolution of plexiform lesions in pulmonary hypertension associated with scleroderma and human immunodeficiency virus infection. Hum Pathol. 1997 Apr; 28(4):434-42.
    View in: PubMed
    Score: 0.066
  69. Hernandez-Saavedra D, Swain K, Tuder R, Petersen SV, Nozik-Grayck E. Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation. Adv Exp Med Biol. 2017; 967:57-70.
    View in: PubMed
    Score: 0.065
  70. Voelkel NF, Hoeper M, Maloney J, Tuder RM. Vascular endothelial growth factor in pulmonary hypertension. Ann N Y Acad Sci. 1996 Oct 31; 796:186-93.
    View in: PubMed
    Score: 0.064
  71. Voelkel NF, Tuder RM. Cellular and molecular mechanisms in the pathogenesis of severe pulmonary hypertension. Eur Respir J. 1995 Dec; 8(12):2129-38.
    View in: PubMed
    Score: 0.060
  72. Kumar R, Mickael C, Chabon J, Gebreab L, Rutebemberwa A, Garcia AR, Koyanagi DE, Sanders L, Gandjeva A, Kearns MT, Barthel L, Janssen WJ, Mauad T, Bandeira A, Schmidt E, Tuder RM, Graham BB. The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension. Am J Respir Crit Care Med. 2015 Oct 15; 192(8):998-1008.
    View in: PubMed
    Score: 0.060
  73. Stenmark KR, Tuder RM, El Kasmi KC. Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension. J Appl Physiol (1985). 2015 Nov 15; 119(10):1164-72.
    View in: PubMed
    Score: 0.058
  74. Drake KM, Comhair SA, Erzurum SC, Tuder RM, Aldred MA. Endothelial chromosome 13 deletion in congenital heart disease-associated pulmonary arterial hypertension dysregulates SMAD9 signaling. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):850-4.
    View in: PubMed
    Score: 0.057
  75. Cavasin MA, Demos-Davies KM, Schuetze KB, Blakeslee WW, Stratton MS, Tuder RM, McKinsey TA. Reversal of severe angioproliferative pulmonary arterial hypertension and right ventricular hypertrophy by combined phosphodiesterase-5 and endothelin receptor inhibition. J Transl Med. 2014 Nov 26; 12:314.
    View in: PubMed
    Score: 0.056
  76. El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR. Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. J Immunol. 2014 Jul 15; 193(2):597-609.
    View in: PubMed
    Score: 0.054
  77. Voelkel NF, Tuder R. Interleukin-1 receptor antagonist inhibits pulmonary hypertension induced by inflammation. Ann N Y Acad Sci. 1994 May 28; 725:104-9.
    View in: PubMed
    Score: 0.054
  78. Lahm T, Tuder RM, Petrache I. Progress in solving the sex hormone paradox in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2014 Jul 01; 307(1):L7-26.
    View in: PubMed
    Score: 0.054
  79. Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW. Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2014 May 01; 189(9):1110-20.
    View in: PubMed
    Score: 0.054
  80. Tuder RM, Groves B, Badesch DB, Voelkel NF. Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension. Am J Pathol. 1994 Feb; 144(2):275-85.
    View in: PubMed
    Score: 0.053
  81. Dweik RA, Rounds S, Erzurum SC, Archer S, Fagan K, Hassoun PM, Hill NS, Humbert M, Kawut SM, Krowka M, Michelakis E, Morrell NW, Stenmark K, Tuder RM, Newman J. An official American Thoracic Society Statement: pulmonary hypertension phenotypes. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):345-55.
    View in: PubMed
    Score: 0.053
  82. Goncharov DA, Kudryashova TV, Ziai H, Ihida-Stansbury K, DeLisser H, Krymskaya VP, Tuder RM, Kawut SM, Goncharova EA. Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension. Circulation. 2014 Feb 25; 129(8):864-74.
    View in: PubMed
    Score: 0.052
  83. Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, Springer DA, Rouault TA. Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2a. Cell Metab. 2013 Feb 05; 17(2):271-81.
    View in: PubMed
    Score: 0.049
  84. Lundgrin EL, Park MM, Sharp J, Tang WH, Thomas JD, Asosingh K, Comhair SA, DiFilippo FP, Neumann DR, Davis L, Graham BB, Tuder RM, Dostanic I, Erzurum SC. Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year. Ann Am Thorac Soc. 2013 Feb; 10(1):1-9.
    View in: PubMed
    Score: 0.049
  85. Asosingh K, Farha S, Lichtin A, Graham B, George D, Aldred M, Hazen SL, Loyd J, Tuder R, Erzurum SC. Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension. Blood. 2012 Aug 09; 120(6):1218-27.
    View in: PubMed
    Score: 0.047
  86. Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J Clin Invest. 2011 Nov; 121(11):4548-66.
    View in: PubMed
    Score: 0.045
  87. Meadows CA, Risbano MG, Zhang L, Geraci MW, Tuder RM, Collier DH, Bull TM. Increased expression of growth differentiation factor-15 in systemic sclerosis-associated pulmonary arterial hypertension. Chest. 2011 May; 139(5):994-1002.
    View in: PubMed
    Score: 0.042
  88. Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD. Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2010 Nov 01; 182(9):1153-60.
    View in: PubMed
    Score: 0.041
  89. Sehgal PB, Mukhopadhyay S, Patel K, Xu F, Almod?var S, Tuder RM, Flores SC. Golgi dysfunction is a common feature in idiopathic human pulmonary hypertension and vascular lesions in SHIV-nef-infected macaques. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L729-37.
    View in: PubMed
    Score: 0.039
  90. Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. Am J Respir Cell Mol Biol. 2009 Nov; 41(5):553-61.
    View in: PubMed
    Score: 0.038
  91. Tuder RM, Yun JH. Vascular endothelial growth factor of the lung: friend or foe. Curr Opin Pharmacol. 2008 Jun; 8(3):255-60.
    View in: PubMed
    Score: 0.036
  92. Asosingh K, Aldred MA, Vasanji A, Drazba J, Sharp J, Farver C, Comhair SA, Xu W, Licina L, Huang L, Anand-Apte B, Yoder MC, Tuder RM, Erzurum SC. Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol. 2008 Mar; 172(3):615-27.
    View in: PubMed
    Score: 0.035
  93. Grigoryev DN, Mathai SC, Fisher MR, Girgis RE, Zaiman AL, Housten-Harris T, Cheadle C, Gao L, Hummers LK, Champion HC, Garcia JG, Wigley FM, Tuder RM, Barnes KC, Hassoun PM. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Transl Res. 2008 Apr; 151(4):197-207.
    View in: PubMed
    Score: 0.035
  94. Mukhopadhyay S, Shah M, Xu F, Patel K, Tuder RM, Sehgal PB. Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2008 Mar; 294(3):L449-68.
    View in: PubMed
    Score: 0.035
  95. Tuder RM, Yun JH, Bhunia A, Fijalkowska I. Hypoxia and chronic lung disease. J Mol Med (Berl). 2007 Dec; 85(12):1317-24.
    View in: PubMed
    Score: 0.034
  96. Girgis RE, Mozammel S, Champion HC, Li D, Peng X, Shimoda L, Tuder RM, Johns RA, Hassoun PM. Regression of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1105-10.
    View in: PubMed
    Score: 0.033
  97. Marecki JC, Cool CD, Parr JE, Beckey VE, Luciw PA, Tarantal AF, Carville A, Shannon RP, Cota-Gomez A, Tuder RM, Voelkel NF, Flores SC. HIV-1 Nef is associated with complex pulmonary vascular lesions in SHIV-nef-infected macaques. Am J Respir Crit Care Med. 2006 Aug 15; 174(4):437-45.
    View in: PubMed
    Score: 0.031
  98. Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Cool C, Wood K, Tuder RM, Burns N, Kasper M, Voelkel NF. Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2006 Oct; 291(4):L668-76.
    View in: PubMed
    Score: 0.031
  99. Voelkel NF, Vandivier RW, Tuder RM. Vascular endothelial growth factor in the lung. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L209-21.
    View in: PubMed
    Score: 0.030
  100. West J, Tada Y, Fagan KA, Steudel W, Fouty BW, Harral JW, Miller M, Ozimek J, Tuder RM, Rodman DM. Suppression of type II bone morphogenic protein receptor in vascular smooth muscle induces pulmonary arterial hypertension in transgenic mice. Chest. 2005 Dec; 128(6 Suppl):553S.
    View in: PubMed
    Score: 0.030
  101. Girgis RE, Ma SF, Ye S, Grigoryev DN, Li D, Hassoun PM, Tuder RM, Johns RA, Garcia JG. Differential gene expression in chronic hypoxic pulmonary hypertension: effect of simvastatin treatment. Chest. 2005 Dec; 128(6 Suppl):579S.
    View in: PubMed
    Score: 0.030
  102. Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, Tuder RM, Voelkel NF, Gail DB. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 2004 Jun 22; 109(24):2947-52.
    View in: PubMed
    Score: 0.027
  103. West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R, Rodman DM. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circ Res. 2004 Apr 30; 94(8):1109-14.
    View in: PubMed
    Score: 0.027
  104. Budhiraja R, Tuder RM, Hassoun PM. Endothelial dysfunction in pulmonary hypertension. Circulation. 2004 Jan 20; 109(2):159-65.
    View in: PubMed
    Score: 0.026
  105. Jones JE, Walker JL, Song Y, Weiss N, Cardoso WV, Tuder RM, Loscalzo J, Zhang YY. Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats. Am J Physiol Heart Circ Physiol. 2004 May; 286(5):H1775-84.
    View in: PubMed
    Score: 0.026
  106. Tuder RM, McGrath S, Voelkel NF, Geraci MW. Oxygen-dependent regulation of pulmonary circulation. Methods Enzymol. 2004; 381:87-106.
    View in: PubMed
    Score: 0.026
  107. Bowers R, Cool C, Murphy RC, Tuder RM, Hopken MW, Flores SC, Voelkel NF. Oxidative stress in severe pulmonary hypertension. Am J Respir Crit Care Med. 2004 Mar 15; 169(6):764-9.
    View in: PubMed
    Score: 0.026
  108. Bull TM, Golpon H, Hebbel RP, Solovey A, Cool CD, Tuder RM, Geraci MW, Voelkel NF. Circulating endothelial cells in pulmonary hypertension. Thromb Haemost. 2003 Oct; 90(4):698-703.
    View in: PubMed
    Score: 0.026
  109. Cool CD, Rai PR, Yeager ME, Hernandez-Saavedra D, Serls AE, Bull TM, Geraci MW, Brown KK, Routes JM, Tuder RM, Voelkel NF. Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med. 2003 Sep 18; 349(12):1113-22.
    View in: PubMed
    Score: 0.026
  110. Girgis RE, Li D, Zhan X, Garcia JG, Tuder RM, Hassoun PM, Johns RA. Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Heart Circ Physiol. 2003 Sep; 285(3):H938-45.
    View in: PubMed
    Score: 0.025
  111. Le Cras TD, Markham NE, Tuder RM, Voelkel NF, Abman SH. Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure. Am J Physiol Lung Cell Mol Physiol. 2002 Sep; 283(3):L555-62.
    View in: PubMed
    Score: 0.024
  112. Taraseviciene-Stewart L, Gera L, Hirth P, Voelkel NF, Tuder RM, Stewart JM. A bradykinin antagonist and a caspase inhibitor prevent severe pulmonary hypertension in a rat model. Can J Physiol Pharmacol. 2002 Apr; 80(4):269-74.
    View in: PubMed
    Score: 0.023
  113. Geraci MW, Hoshikawa Y, Yeager M, Golpon H, Gesell T, Tuder RM, Voelkel NF. Gene expression profiles in pulmonary hypertension. Chest. 2002 Mar; 121(3 Suppl):104S-105S.
    View in: PubMed
    Score: 0.023
  114. Geraci MW, Moore M, Gesell T, Yeager ME, Alger L, Golpon H, Gao B, Loyd JE, Tuder RM, Voelkel NF. Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis. Circ Res. 2001 Mar 30; 88(6):555-62.
    View in: PubMed
    Score: 0.022
  115. Golpon HA, Geraci MW, Moore MD, Miller HL, Miller GJ, Tuder RM, Voelkel NF. HOX genes in human lung: altered expression in primary pulmonary hypertension and emphysema. Am J Pathol. 2001 Mar; 158(3):955-66.
    View in: PubMed
    Score: 0.022
  116. Le Cras TD, Kim DH, Gebb S, Markham NE, Shannon JM, Tuder RM, Abman SH. Abnormal lung growth and the development of pulmonary hypertension in the Fawn-Hooded rat. Am J Physiol. 1999 10; 277(4):L709-18.
    View in: PubMed
    Score: 0.020
  117. Geraci MW, Gao B, Shepherd DC, Moore MD, Westcott JY, Fagan KA, Alger LA, Tuder RM, Voelkel NF. Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension. J Clin Invest. 1999 Jun; 103(11):1509-15.
    View in: PubMed
    Score: 0.019
  118. Cohen AJ, Cool C, Gorg S, Gilman LB, Tuder RM, Miller YE, Voelkel NF. Low or absent peptidase expression in plexiform lesions of primary pulmonary hypertension. Chest. 1998 Jul; 114(1 Suppl):30S-31S.
    View in: PubMed
    Score: 0.018
  119. Wright L, Tuder RM, Wang J, Cool CD, Lepley RA, Voelkel NF. 5-Lipoxygenase and 5-lipoxygenase activating protein (FLAP) immunoreactivity in lungs from patients with primary pulmonary hypertension. Am J Respir Crit Care Med. 1998 Jan; 157(1):219-29.
    View in: PubMed
    Score: 0.017
  120. Villamor E, Le Cras TD, Horan MP, Halbower AC, Tuder RM, Abman SH. Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus. Am J Physiol. 1997 May; 272(5 Pt 1):L1013-20.
    View in: PubMed
    Score: 0.017
  121. Ivy DD, Parker TA, Ziegler JW, Galan HL, Kinsella JP, Tuder RM, Abman SH. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. J Clin Invest. 1997 Mar 15; 99(6):1179-86.
    View in: PubMed
    Score: 0.016
  122. Voelkel NF, Tuder RM, Wade K, H?per M, Lepley RA, Goulet JL, Koller BH, Fitzpatrick F. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. J Clin Invest. 1996 Jun 01; 97(11):2491-8.
    View in: PubMed
    Score: 0.016
  123. Voelkel NF, Tuder RM, Bridges J, Arend WP. Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline. Am J Respir Cell Mol Biol. 1994 Dec; 11(6):664-75.
    View in: PubMed
    Score: 0.014
  124. Gebska MA, Stevenson BK, Hemnes AR, Bivalacqua TJ, Haile A, Hesketh GG, Murray CI, Zaiman AL, Halushka MK, Krongkaew N, Strong TD, Cooke CA, El-Haddad H, Tuder RM, Berkowitz DE, Champion HC. Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. Cardiovasc Res. 2011 May 01; 90(2):353-63.
    View in: PubMed
    Score: 0.011
  125. Lee JE, Patel K, Almod?var S, Tuder RM, Flores SC, Sehgal PB. Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1141-58.
    View in: PubMed
    Score: 0.011
  126. Kolosionek E, Graham BB, Tuder RM, Butrous G. Pulmonary vascular disease associated with parasitic infection--the role of schistosomiasis. Clin Microbiol Infect. 2011 Jan; 17(1):15-24.
    View in: PubMed
    Score: 0.011
  127. Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):250-5.
    View in: PubMed
    Score: 0.009
  128. Xu W, Koeck T, Lara AR, Neumann D, DiFilippo FP, Koo M, Janocha AJ, Masri FA, Arroliga AC, Jennings C, Dweik RA, Tuder RM, Stuehr DJ, Erzurum SC. Alterations of cellular bioenergetics in pulmonary artery endothelial cells. Proc Natl Acad Sci U S A. 2007 Jan 23; 104(4):1342-7.
    View in: PubMed
    Score: 0.008
  129. Hoshikawa Y, Nana-Sinkam P, Moore MD, Sotto-Santiago S, Phang T, Keith RL, Morris KG, Kondo T, Tuder RM, Voelkel NF, Geraci MW. Hypoxia induces different genes in the lungs of rats compared with mice. Physiol Genomics. 2003 Feb 06; 12(3):209-19.
    View in: PubMed
    Score: 0.006
  130. Badesch DB, Zamora M, Fullerton D, Weill D, Tuder R, Grover F, Schwarz MI. Pulmonary capillaritis: a possible histologic form of acute pulmonary allograft rejection. J Heart Lung Transplant. 1998 Apr; 17(4):415-22.
    View in: PubMed
    Score: 0.004
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