 Connection
David Orlicky to Male
This is a "connection" page, showing publications David Orlicky has written about Male.
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Orlicky DJ, Libby AE, Bales ES, McMahan RH, Monks J, La Rosa FG, McManaman JL. Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions. J Physiol. 2019 03; 597(6):1565-1584.
Score: 0.021
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Orlicky DJ, Roede JR, Bales E, Greenwood C, Greenberg A, Petersen D, McManaman JL. Chronic ethanol consumption in mice alters hepatocyte lipid droplet properties. Alcohol Clin Exp Res. 2011 Jun; 35(6):1020-33.
Score: 0.013
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Malyshkina A, Solar M, Balasubramaniyan N, Zheng L, McCulley DJ, Morro M, Seymour C, Sajti E, Orlicky DJ, Sosa A, Smith BJ, Wright CJ. TLR9-mediated innate immune signaling contributes to acetaminophen-induced injury in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2026 Jul 01; 331(1):L16-L33.
Score: 0.009
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Ghosh S, Devereaux MW, Anderson AL, Anderson CC, D'Alessandro A, Orlicky DJ, Sokol RJ. Dietary Lauric Acid Suppresses Inflammation, Cholestasis, Hepatocyte Injury, and Senescence in 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-induced Inflammatory Cholangiopathy. Cell Mol Gastroenterol Hepatol. 2026; 20(5):101731.
Score: 0.009
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Dunn LN, Niemeyer BF, Eduthan NP, Schade KA, Waugh KA, Brown C, Rachubinski AL, Timkovich AE, Orlicky DJ, Galbraith MD, Espinosa JM, Sullivan KD. Altered hepatic metabolism in Down syndrome. Cell Rep. 2026 Jan 27; 45(1):116835.
Score: 0.009
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Callahan RC, Curry JC, Bhagavatula G, Staley AW, Schaefer RE, Minhajuddin F, Zhou L, Neuhart RM, Atif SM, Orlicky DJ, Cartwright IM, Gerich ME, Steiner CA, Theiss AL, Hall CH, Colgan SP, Onyiah JC. Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner. JCI Insight. 2026 Feb 09; 11(3).
Score: 0.009
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Walrath TM, Evans MR, Meza Monge K, Najarro KM, Orlicky DJ, Idrovo JP, McMahan RH, Kovacs EJ. Impaired intestinal cell proliferation parallels increased senescence after burn injury in aged mice. Am J Physiol Gastrointest Liver Physiol. 2026 01 01; 330(1):G1-G9.
Score: 0.009
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Andres-Hernando A, Orlicky DJ, Garcia GE, Loetz EC, Montoya R, Kumar V, Effinger DP, Kuwabara M, Bae SY, Lorenzo-Rebenaque L, Fauste E, Bell RL, Grahame N, Liangpunsakul S, Kim H, Dugar S, Maffuid P, Nakagawa T, Wempe MF, Petrash JM, Tolan DR, Bland ST, Johnson RJ, Lanaspa MA. Identification of a common ketohexokinase-dependent link driving alcohol intake and alcohol-associated liver disease in mice. Nat Metab. 2025 Nov; 7(11):2250-2267.
Score: 0.009
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Haque PS, Paris SL, Souza RF, Onyiah JC, Coughlan C, Orlicky DJ, Zempleni J, Theiss AL. Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis. Cancer Lett. 2025 Dec 28; 635:218104.
Score: 0.009
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McMahan RH, Najarro KM, Giesy LE, Evans MR, Schnabl B, Orlicky DJ, Frank DN, Kovacs EJ. Intestinal REG3G Protects Against Gastrointestinal Dysfunction in a Murine Model of Ethanol Intoxication and Burn Injury. Shock. 2026 Mar 01; 65(3):528-537.
Score: 0.009
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Khair S, Najarro KM, Walrath TM, Orlicky DJ, McMahan RH, Kovacs EJ. Post-burn Lung Inflammation Is Associated With Induction of Pulmonary Cathelicidin-related Antimicrobial Peptide and S100a8 in Mice. J Burn Care Res. 2025 08 30; 46(4):917-926.
Score: 0.008
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Livingston PD, Labbate Bonaldo AL, Jamnick NA, Weinzierl NM, Gammon CJ, Callaway CS, Lee S, Gao B, Goodspeed A, Carvalho RF, Young CD, Orlicky DJ, Adams DJ, Novinger LJ, Bonetto A. B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer. Am J Physiol Cell Physiol. 2025 08 01; 329(2):C646-C658.
Score: 0.008
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Strand R, Orlicky DJ, Chen Y. Gene-dose effect of the glutathione biosynthesis gene on ascorbate deficiency in mice. Biochem Biophys Res Commun. 2025 06 20; 766:151900.
Score: 0.008
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Kremer KN, Khammash HA, Miranda AM, Rutt LN, Twardy SM, Anton PE, Campbell ML, Garza-Ortiz C, Orlicky DJ, Pelanda R, McCullough RL, Torres RM. Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance. Front Immunol. 2024; 15:1497788.
Score: 0.008
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Rutt LN, Orlicky DJ, McCullough RL. Investigating the role of Wnt3a and Wnt5a as critical factors of hepatic stellate cell activation in acute toxicant-induced liver injury. Cell Biol Toxicol. 2024 12 21; 41(1):5.
Score: 0.008
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Shearn CT, Anderson AL, Devereaux MW, Koch SD, Larsen LD, Spencer LA, Orlicky DJ, Colgan SP, Steiner CA, Sokol RJ. Overexpression of TNFa in TNF?ARE+/- mice increases hepatic periportal inflammation and alters bile acid signaling in mice. Hepatol Commun. 2024 12 01; 8(12).
Score: 0.008
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Walrath T, Najarro KM, Giesy LE, Khair S, Orlicky DJ, McMahan RH, Kovacs EJ. Reducing the excessive inflammation after burn injury in aged mice by maintaining a healthier intestinal microbiome. FASEB J. 2024 09 30; 38(18):e70065.
Score: 0.008
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Wang Y, Charkoftaki G, Orlicky DJ, Davidson E, Aalizadeh R, Sun N, Ginsberg G, Thompson DC, Vasiliou V, Chen Y. CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study. Arch Toxicol. 2024 10; 98(10):3241-3257.
Score: 0.008
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Burtis AEC, DeNicola DMC, Ferguson ME, Santos RG, Pinilla C, Kriss MS, Orlicky DJ, Tamburini BAJ, Gillen AE, Burchill MA. Ag-driven CD8 + T cell clonal expansion is a prominent feature of MASH in humans and mice. Hepatology. 2025 Feb 01; 81(2):591-608.
Score: 0.008
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Maclean KN, Jiang H, Neill PD, Chanin RR, Hurt KJ, Orlicky DJ, Bottiglieri T, Roede JR, Stabler SP. Dysregulation of hepatic one-carbon metabolism in classical homocystinuria: Implications of redox-sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment. FASEB J. 2024 07 15; 38(13):e23795.
Score: 0.008
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Andres-Hernando A, Orlicky DJ, Kuwabara M, Fini MA, Tolan DR, Johnson RJ, Lanaspa MA. Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance. Commun Biol. 2024 07 11; 7(1):849.
Score: 0.008
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Schwab SK, Harris PS, Michel C, McGinnis CD, Nahomi RB, Assiri MA, Reisdorph R, Henriksen K, Orlicky DJ, Levi M, Rosenberg A, Nagaraj RH, Fritz KS. Quantifying Protein Acetylation in Diabetic Nephropathy from Formalin-Fixed Paraffin-Embedded Tissue. Proteomics Clin Appl. 2024 11; 18(6):e202400018.
Score: 0.008
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Baker PR, Li AS, Griffin BR, Gil HW, Orlicky DJ, Fox BM, Park B, Sparagna GC, Goff J, Altmann C, Elajaili H, Okamura K, He Z, Stephenson D, D'Alessandro A, Reisz JA, Nozik ES, Sucharov CC, Faubel S. Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice. Sci Rep. 2024 06 15; 14(1):13862.
Score: 0.008
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Khair S, Walrath TM, Curtis BJ, Orlicky DJ, McMahan RH, Kovacs EJ. Ethanol exacerbates pulmonary complications after burn injury in mice, regardless of frequency of ethanol exposures. Burns. 2023 12; 49(8):1935-1943.
Score: 0.007
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Okamura K, Lu S, He Z, Altmann C, Montford JR, Li AS, Lucia MS, Orlicky DJ, Weiser-Evans M, Faubel S. IL-6 mediates the hepatic acute phase response after prerenal azotemia in a clinically defined murine model. Am J Physiol Renal Physiol. 2023 09 01; 325(3):F328-F344.
Score: 0.007
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McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 05 01; 210(9):1372-1385.
Score: 0.007
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Solar M, Grayck MR, McCarthy WC, Zheng L, Lacayo OA, Sherlock LG, Zhou R, Orlicky DJ, Wright CJ. Absence of I?Bß/NF?B signaling does not attenuate acetaminophen-induced hepatic injury. Anat Rec (Hoboken). 2025 04; 308(4):1251-1264.
Score: 0.007
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Shearn CT, Anderson AL, Devereux MW, Orlicky DJ, Michel C, Petersen DR, Miller CG, Harpavat S, Schmidt EE, Sokol RJ. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS One. 2022; 17(11):e0276879.
Score: 0.007
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Wang XX, Xie C, Libby AE, Ranjit S, Levi J, Myakala K, Bhasin K, Jones BA, Orlicky DJ, Takahashi S, Dvornikov A, Kleiner DE, Hewitt SM, Adorini L, Kopp JB, Krausz KW, Rosenberg A, McManaman JL, Robertson CE, Ir D, Frank DN, Luo Y, Gonzalez FJ, Gratton E, Levi M. The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice. J Biol Chem. 2022 11; 298(11):102530.
Score: 0.007
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Paudel S, Raina K, Tiku VR, Maurya A, Orlicky DJ, You Z, Rigby CM, Deep G, Kant R, Raina B, Agarwal C, Agarwal R. Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice. Carcinogenesis. 2022 06 27; 43(6):557-570.
Score: 0.007
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El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 02; 75(2):252-265.
Score: 0.007
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Balasubramaniyan N, Devereaux MW, Orlicky DJ, Sokol RJ, Suchy FJ. miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis. J Biol Chem. 2021 12; 297(6):101400.
Score: 0.006
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Niemeyer CS, Mescher T, Griggs R, Orlicky DJ, Wilkerson GK, Bubak AN, Hassell JE, Feia B, Mahalingam R, Traina-Dorge V, Nagel MA. Histopathological Analysis of Adrenal Glands after Simian Varicella Virus Infection. Viruses. 2021 06 26; 13(7).
Score: 0.006
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Dobrinskikh E, Sherlock LG, Orlicky DJ, Zheng L, De Dios R, Balasubramaniyan D, Sizemore T, Butler B, Wright CJ. The developing murine lung is susceptible to acetaminophen toxicity. Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L969-L978.
Score: 0.006
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Andres-Hernando A, Jensen TJ, Kuwabara M, Orlicky DJ, Cicerchi C, Li N, Roncal-Jimenez CA, Garcia GE, Ishimoto T, Maclean PS, Bjornstad P, Sanchez-Lozada LG, Kanbay M, Nakagawa T, Johnson RJ, Lanaspa MA. Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor. JCI Insight. 2021 01 11; 6(1).
Score: 0.006
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Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020 11 17; 33(7):108407.
Score: 0.006
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Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jirón Tamburini BA. Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System. Cell Mol Gastroenterol Hepatol. 2021; 11(2):573-595.
Score: 0.006
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Andres-Hernando A, Kuwabara M, Orlicky DJ, Vandenbeuch A, Cicerchi C, Kinnamon SC, Finger TE, Johnson RJ, Lanaspa MA. Sugar causes obesity and metabolic syndrome in mice independently of sweet taste. Am J Physiol Endocrinol Metab. 2020 08 01; 319(2):E276-E290.
Score: 0.006
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Andres-Hernando A, Orlicky DJ, Kuwabara M, Ishimoto T, Nakagawa T, Johnson RJ, Lanaspa MA. Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction. Cell Metab. 2020 07 07; 32(1):117-127.e3.
Score: 0.006
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Takahashi S, Luo Y, Ranjit S, Xie C, Libby AE, Orlicky DJ, Dvornikov A, Wang XX, Myakala K, Jones BA, Bhasin K, Wang D, McManaman JL, Krausz KW, Gratton E, Ir D, Robertson CE, Frank DN, Gonzalez FJ, Levi M. Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice. J Biol Chem. 2020 04 03; 295(14):4733-4747.
Score: 0.006
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Sandoval J, Orlicky DJ, Allawzi A, Butler B, Ju C, Phan CT, Toston R, De Dios R, Nguyen L, McKenna S, Nozik-Grayck E, Wright CJ. Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung. Oxid Med Cell Longev. 2019; 2019:7595126.
Score: 0.006
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Aivazidis S, Jain A, Rauniyar AK, Anderson CC, Marentette JO, Orlicky DJ, Fritz KS, Harris PS, Siegel D, Maclean KN, Roede JR. SNARE proteins rescue impaired autophagic flux in Down syndrome. PLoS One. 2019; 14(11):e0223254.
Score: 0.006
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McLoughlin MR, Orlicky DJ, Prigge JR, Krishna P, Talago EA, Cavigli IR, Eriksson S, Miller CG, Kundert JA, Sayin VI, Sabol RA, Heinemann J, Brandenberger LO, Iverson SV, Bothner B, Papagiannakopoulos T, Shearn CT, Arnér ESJ, Schmidt EE. TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11408-11417.
Score: 0.005
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McGettigan B, McMahan R, Orlicky D, Burchill M, Danhorn T, Francis P, Cheng LL, Golden-Mason L, Jakubzick CV, Rosen HR. Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages. Hepatology. 2019 07; 70(1):67-83.
Score: 0.005
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Ali HR, Assiri MA, Harris PS, Michel CR, Yun Y, Marentette JO, Huynh FK, Orlicky DJ, Shearn CT, Saba LM, Reisdorph R, Reisdorph N, Hirschey MD, Fritz KS. Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism. J Proteome Res. 2019 04 05; 18(4):1513-1531.
Score: 0.005
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Davenport BJ, Martin CG, Beverley SM, Orlicky DJ, Vazquez-Torres A, Morrison TE. SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice. PLoS Negl Trop Dis. 2018 10; 12(10):e0006921.
Score: 0.005
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Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA. Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia. Cancer Res. 2018 09 01; 78(17):4971-4983.
Score: 0.005
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Shearn CT, Pulliam CF, Pedersen K, Meredith K, Mercer KE, Saba LM, Orlicky DJ, Ronis MJ, Petersen DR. Knockout of the Gsta4 Gene in Male Mice Leads to an Altered Pattern of Hepatic Protein Carbonylation and Enhanced Inflammation Following Chronic Consumption of an Ethanol Diet. Alcohol Clin Exp Res. 2018 07; 42(7):1192-1205.
Score: 0.005
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Petersen DR, Saba LM, Sayin VI, Papagiannakopoulos T, Schmidt EE, Merrill GF, Orlicky DJ, Shearn CT. Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. PLoS One. 2018; 13(5):e0198139.
Score: 0.005
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Monks J, Orlicky DJ, Stefanski AL, Libby AE, Bales ES, Rudolph MC, Johnson GC, Sherk VD, Jackman MR, Williamson K, Carlson NE, MacLean PS, McManaman JL. Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction. Nutr Diabetes. 2018 04 25; 8(1):18.
Score: 0.005
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Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, McClatchey PM, Bauer TA, Regensteiner JG, Reusch JEB. Supplemental Oxygen Improves In Vivo Mitochondrial Oxidative Phosphorylation Flux in Sedentary Obese Adults With Type 2 Diabetes. Diabetes. 2018 07; 67(7):1369-1379.
Score: 0.005
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Wang D, Luo Y, Wang X, Orlicky DJ, Myakala K, Yang P, Levi M. The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Renal and Liver Disease in Western Diet Induced Obesity Mice. Int J Mol Sci. 2018 Jan 03; 19(1).
Score: 0.005
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Shearn CT, Orlicky DJ, Petersen DR. Dysregulation of antioxidant responses in patients diagnosed with concomitant Primary Sclerosing Cholangitis/Inflammatory Bowel Disease. Exp Mol Pathol. 2018 02; 104(1):1-8.
Score: 0.005
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Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D'Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M. FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity. J Am Soc Nephrol. 2018 01; 29(1):118-137.
Score: 0.005
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Shearn CT, Saba LM, Roede JR, Orlicky DJ, Shearn AH, Petersen DR. Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH. Free Radic Biol Med. 2017 12; 113:280-290.
Score: 0.005
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Assiri MA, Roy SR, Harris PS, Ali H, Liang Y, Shearn CT, Orlicky DJ, Roede JR, Hirschey MD, Backos DS, Fritz KS. Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation. Alcohol Clin Exp Res. 2017 Oct; 41(10):1705-1714.
Score: 0.005
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Prigge JR, Coppo L, Martin SS, Ogata F, Miller CG, Bruschwein MD, Orlicky DJ, Shearn CT, Kundert JA, Lytchier J, Herr AE, Mattsson Å, Taylor MP, Gustafsson TN, Arnér ESJ, Holmgren A, Schmidt EE. Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase. Cell Rep. 2017 06 27; 19(13):2771-2781.
Score: 0.005
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Tewari-Singh N, Goswami DG, Kant R, Croutch CR, Casillas RP, Orlicky DJ, Agarwal R. Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity. Toxicol Appl Pharmacol. 2017 02 15; 317:25-32.
Score: 0.005
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Heit C, Marshall S, Singh S, Yu X, Charkoftaki G, Zhao H, Orlicky DJ, Fritz KS, Thompson DC, Vasiliou V. Catalase deletion promotes prediabetic phenotype in mice. Free Radic Biol Med. 2017 02; 103:48-56.
Score: 0.005
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Osna NA, Feng D, Ganesan M, Maillacheruvu PF, Orlicky DJ, French SW, Tuma DJ, Kharbanda KK. Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury. World J Gastroenterol. 2016 Oct 14; 22(38):8497-8508.
Score: 0.005
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Rigby CM, Roy S, Deep G, Guillermo-Lagae R, Jain AK, Dhar D, Orlicky DJ, Agarwal C, Agarwal R. Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis. Carcinogenesis. 2017 01; 38(1):40-50.
Score: 0.005
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McGettigan BM, McMahan RH, Luo Y, Wang XX, Orlicky DJ, Porsche C, Levi M, Rosen HR. Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease. J Biol Chem. 2016 10 28; 291(44):23058-23067.
Score: 0.005
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Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS One. 2016; 11(4):e0154152.
Score: 0.004
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Shearn CT, Orlicky DJ, Saba LM, Shearn AH, Petersen DR. Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis. Free Radic Biol Med. 2015 Dec; 89:1144-53.
Score: 0.004
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Frank DN, Bales ES, Monks J, Jackman MJ, MacLean PS, Ir D, Robertson CE, Orlicky DJ, McManaman JL. Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine. PLoS One. 2015; 10(7):e0131944.
Score: 0.004
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Harris PS, Roy SR, Coughlan C, Orlicky DJ, Liang Y, Shearn CT, Roede JR, Fritz KS. Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney. Redox Biol. 2015 Dec; 6:33-40.
Score: 0.004
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Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R. Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin. Toxicol Appl Pharmacol. 2015 May 15; 285(1):71-8.
Score: 0.004
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Ronis MJ, Mercer KE, Gannon B, Engi B, Zimniak P, Shearn CT, Orlicky DJ, Albano E, Badger TM, Petersen DR. Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-a double knockout mice enhance injury during early stages of alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 01; 308(5):G403-15.
Score: 0.004
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Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R. Topical nitrogen mustard exposure causes systemic toxic effects in mice. Exp Toxicol Pathol. 2015 Feb; 67(2):161-70.
Score: 0.004
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Kharbanda KK, Todero SL, Thomes PG, Orlicky DJ, Osna NA, French SW, Tuma DJ. Increased methylation demand exacerbates ethanol-induced liver injury. Exp Mol Pathol. 2014 Aug; 97(1):49-56.
Score: 0.004
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Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. PLoS One. 2014; 9(5):e96553.
Score: 0.004
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Shearn CT, Backos DS, Orlicky DJ, Smathers-McCullough RL, Petersen DR. Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol. J Biol Chem. 2014 May 30; 289(22):15449-62.
Score: 0.004
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Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries. Toxicology. 2014 Jun 05; 320:25-33.
Score: 0.004
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Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Exp Toxicol Pathol. 2014 Mar; 66(2-3):129-38.
Score: 0.004
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Shearn CT, Smathers RL, Backos DS, Reigan P, Orlicky DJ, Petersen DR. Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis. Free Radic Biol Med. 2013 Dec; 65:680-692.
Score: 0.004
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Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR. Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis. J Nutr Biochem. 2013 Aug; 24(8):1436-45.
Score: 0.004
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McManaman JL, Bales ES, Orlicky DJ, Jackman M, MacLean PS, Cain S, Crunk AE, Mansur A, Graham CE, Bowman TA, Greenberg AS. Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res. 2013 May; 54(5):1346-59.
Score: 0.004
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Smathers RL, Galligan JJ, Shearn CT, Fritz KS, Mercer K, Ronis M, Orlicky DJ, Davidson NO, Petersen DR. Susceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver. J Lipid Res. 2013 May; 54(5):1335-45.
Score: 0.004
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Martin-Murphy BV, Kominsky DJ, Orlicky DJ, Donohue TM, Ju C. Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury. Hepatology. 2013 Apr; 57(4):1575-84.
Score: 0.004
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Orlicky DJ, Williams-Skipp C. Immunohistochemical localization of PGF2 alpha receptor in the mouse testis. Prostaglandins Leukot Essent Fatty Acids. 1992 Dec; 47(4):247-52.
Score: 0.003
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Gentile CL, Nivala AM, Gonzales JC, Pfaffenbach KT, Wang D, Wei Y, Jiang H, Orlicky DJ, Petersen DR, Pagliassotti MJ, Maclean KN. Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. Am J Physiol Regul Integr Comp Physiol. 2011 Dec; 301(6):R1710-22.
Score: 0.003
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O'Neill HC, Orlicky DJ, Hendry-Hofer TB, Loader JE, Day BJ, White CW. Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):323-31.
Score: 0.003
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Jain AK, Tewari-Singh N, Orlicky DJ, White CW, Agarwal R. 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin. Toxicology. 2011 Apr 11; 282(3):129-38.
Score: 0.003
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Marchitti SA, Orlicky DJ, Brocker C, Vasiliou V. Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues. J Histochem Cytochem. 2010 Sep; 58(9):765-83.
Score: 0.003
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Stagos D, Chen Y, Brocker C, Donald E, Jackson BC, Orlicky DJ, Thompson DC, Vasiliou V. Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos. 2010 Oct; 38(10):1679-87.
Score: 0.003
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Roede JR, Orlicky DJ, Fisher AB, Petersen DR. Overexpression of peroxiredoxin 6 does not prevent ethanol-mediated oxidative stress and may play a role in hepatic lipid accumulation. J Pharmacol Exp Ther. 2009 Jul; 330(1):79-88.
Score: 0.003
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Marchitti SA, Orlicky DJ, Vasiliou V. Expression and initial characterization of human ALDH3B1. Biochem Biophys Res Commun. 2007 May 11; 356(3):792-8.
Score: 0.002
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Redente EF, Orlicky DJ, Bouchard RJ, Malkinson AM. Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice. Am J Pathol. 2007 Feb; 170(2):693-708.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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