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Connection

Uwe Christians to Adult

This is a "connection" page, showing publications Uwe Christians has written about Adult.

 
Connection Strength
  
 
 
0.444
  
  1. Alloway RR, Vinks AA, Fukuda T, Mizuno T, King EC, Zou Y, Jiang W, Woodle ES, Tremblay S, Klawitter J, Klawitter J, Christians U. Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial. PLoS Med. 2017 Nov; 14(11):e1002428.
    View in: PubMed
    Score: 0.030
  2. Klepacki J, Klawitter J, Klawitter J, Thurman JM, Christians U. A high-performance liquid chromatography-tandem mass spectrometry-based targeted metabolomics kidney dysfunction marker panel in human urine. Clin Chim Acta. 2015 Jun 15; 446:43-53.
    View in: PubMed
    Score: 0.025
  3. Klawitter J, Haschke M, Kahle C, Dingmann C, Klawitter J, Leibfritz D, Christians U. Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose. Br J Clin Pharmacol. 2010 Aug; 70(2):241-51.
    View in: PubMed
    Score: 0.018
  4. Steudel W, Dingmann C, Zhang YL, Bendrick-Peart J, Clavijo C, Shulze J, Betts R, Christians U. Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals. J Clin Pharmacol. 2011 Jan; 51(1):29-39.
    View in: PubMed
    Score: 0.017
  5. Christians U, Strom T, Zhang YL, Steudel W, Schmitz V, Trump S, Haschke M. Active drug transport of immunosuppressants: new insights for pharmacokinetics and pharmacodynamics. Ther Drug Monit. 2006 Feb; 28(1):39-44.
    View in: PubMed
    Score: 0.013
  6. Mayne G, DeWitt PE, Wen J, Schniedewind B, Dabelea D, Christians U, Hurt KJ. Adiponectin and Glucocorticoids Modulate Risk for Preterm Birth: The Healthy Start Study. J Clin Endocrinol Metab. 2025 Jan 21; 110(2):523-533.
    View in: PubMed
    Score: 0.012
  7. Moore BF, Mueller NT, Perng W, Sauder KA, H?bert ET, Hoyt AT, Wymore EM, Boyle KE, Su EJ, Shapiro ALB, Kinney G, Sempio C, Klawitter J, Christians U, Dabelea D. Impact of prenatal exposure to delta 9-tetrahydrocannabinol and cannabidiol on birth size and postnatal growth trajectories. Pediatr Obes. 2025 Jan; 20(1):e13187.
    View in: PubMed
    Score: 0.012
  8. Spindle TR, Zamarripa CA, Russo E, Pollak L, Bigelow G, Ward AM, Tompson B, Sempio C, Shokati T, Klawitter J, Christians U, Vandrey R. Vaporized D-limonene selectively mitigates the acute anxiogenic effects of ?9-tetrahydrocannabinol in healthy adults who intermittently use cannabis. Drug Alcohol Depend. 2024 Apr 01; 257:111267.
    View in: PubMed
    Score: 0.011
  9. Martin EL, Baker NL, Sempio C, Christians U, Klawitter J, McRae-Clark AL. Sex differences in endocannabinoid tone in a pilot study of cannabis use disorder and acute cannabis abstinence. Addict Biol. 2023 10; 28(10):e13337.
    View in: PubMed
    Score: 0.011
  10. Hoffman MC, Hunter SJ, D'Alessandro A, Christians U, Law AJ, Freedman R. Maternal Plasma Choline during Gestation and Small for Gestational Age Infants. Am J Perinatol. 2024 05; 41(S 01):e939-e948.
    View in: PubMed
    Score: 0.011
  11. Klawitter J, Jackson MJ, Smith PH, Hopp K, Chonchol M, Gitomer BY, Cadnapaphornchai MA, Christians U, Klawitter J. Kynurenines in polycystic kidney disease. J Nephrol. 2023 01; 36(1):83-91.
    View in: PubMed
    Score: 0.010
  12. Christians U, Jacobsen W, Benet LZ, Lampen A. Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet. 2002; 41(11):813-51.
    View in: PubMed
    Score: 0.010
  13. van Hoogdalem MW, Johnson TN, McPhail BT, Kamatkar S, Wexelblatt SL, Ward LP, Christians U, Akinbi HT, Vinks AA, Mizuno T. Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome. Clin Pharmacol Ther. 2022 02; 111(2):496-508.
    View in: PubMed
    Score: 0.010
  14. Hunter SK, Hoffman MC, McCarthy L, D'Alessandro A, Wyrwa A, Noonan K, Christians U, Nakimuli-Mpungu E, Zeisel SH, Law AJ, Freedman R. Black American Maternal Prenatal Choline, Offspring Gestational Age at Birth, and Developmental Predisposition to Mental Illness. Schizophr Bull. 2021 07 08; 47(4):896-905.
    View in: PubMed
    Score: 0.010
  15. Mancinelli LM, Frassetto L, Floren LC, Dressler D, Carrier S, Bekersky I, Benet LZ, Christians U. The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups. Clin Pharmacol Ther. 2001 Jan; 69(1):24-31.
    View in: PubMed
    Score: 0.009
  16. Hinckley JD, Saba L, Raymond K, Bartels K, Klawitter J, Christians U, Hopfer C. An Approach to Biomarker Discovery of Cannabis Use Utilizing Proteomic, Metabolomic, and Lipidomic Analyses. Cannabis Cannabinoid Res. 2022 02; 7(1):65-77.
    View in: PubMed
    Score: 0.009
  17. Canafax DM, Irish WD, Moran HB, Squiers E, Levy R, Pouletty P, First MR, Christians U. An individual bioequivalence approach to compare the intrasubject variability of two ciclosporin formulations, SangCya and Neoral. Pharmacology. 1999 Aug; 59(2):78-88.
    View in: PubMed
    Score: 0.008
  18. Lichvar A, Tremblay S, Naik D, Lipscomb J, King E, Vinks AA, Christians U, Alloway RR. Evaluation of Clinical and Safety Outcomes Following Uncontrolled Tacrolimus Conversion in Adult Transplant Recipients. Pharmacotherapy. 2019 05; 39(5):564-575.
    View in: PubMed
    Score: 0.008
  19. Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ?-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. J Inherit Metab Dis. 2019 05; 42(3):424-437.
    View in: PubMed
    Score: 0.008
  20. Keller AC, Klawitter J, Hildreth KL, Christians U, Putnam K, Kohrt WM, Reusch JEB, Moreau KL. Elevated plasma homocysteine and cysteine are associated with endothelial dysfunction across menopausal stages in healthy women. J Appl Physiol (1985). 2019 06 01; 126(6):1533-1540.
    View in: PubMed
    Score: 0.008
  21. Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC. Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development. J Pediatr. 2019 05; 208:198-206.e2.
    View in: PubMed
    Score: 0.008
  22. Leino AD, King EC, Jiang W, Vinks AA, Klawitter J, Christians U, Woodle ES, Alloway RR, Rohan JM. Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values. Am J Transplant. 2019 05; 19(5):1410-1420.
    View in: PubMed
    Score: 0.008
  23. Jalal D, Renner B, Laskowski J, Stites E, Cooper J, Valente K, You Z, Perrenoud L, Le Quintrec M, Muhamed I, Christians U, Klawitter J, Lindorfer MA, Taylor RP, Holers VM, Thurman JM. Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease. J Am Heart Assoc. 2018 07 13; 7(14).
    View in: PubMed
    Score: 0.008
  24. Lesche D, Sigurdardottir V, Leichtle AB, Nakas CT, Christians U, Englberger L, Fiedler M, Largiad?r CR, Mohacsi P, Sistonen J. Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement. Metabolomics. 2017 11 25; 14(1):3.
    View in: PubMed
    Score: 0.007
  25. Schroeder T, Piantadosi CA, Natoli MJ, Autmizguine J, Cohen-Wolkowieczs M, Hamilton KL, Bell C, Klawitter J, Christians U, Irwin DC, Noveck RJ. Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia. Clin Pharmacol Ther. 2018 05; 103(5):888-898.
    View in: PubMed
    Score: 0.007
  26. Sperschneider H, Wagner C, Korn A, Christians U. [Effect of diltiazem on concentration of cyclosporin metabolites in Sandimmune and Neoral treated kidney transplant patients]. Med Klin (Munich). 1997 Oct 15; 92(10):589-96.
    View in: PubMed
    Score: 0.007
  27. Olbricht C, Wanner C, Eisenhauer T, Kliem V, Doll R, Boddaert M, O'Grady P, Krekler M, Mangold B, Christians U. Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Clin Pharmacol Ther. 1997 Sep; 62(3):311-21.
    View in: PubMed
    Score: 0.007
  28. Klawitter J, Hildreth KL, Christians U, Kohrt WM, Moreau KL. A relative L-arginine deficiency contributes to endothelial dysfunction across the stages of the menopausal transition. Physiol Rep. 2017 Sep; 5(17).
    View in: PubMed
    Score: 0.007
  29. Kem WR, Olincy A, Johnson L, Harris J, Wagner BD, Buchanan RW, Christians U, Freedman R. Pharmacokinetic Limitations on Effects of an Alpha7-Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended-Release Formulation. Neuropsychopharmacology. 2018 02; 43(3):583-589.
    View in: PubMed
    Score: 0.007
  30. Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T. The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans. Can J Physiol Pharmacol. 2017 Sep; 95(9):1009-1018.
    View in: PubMed
    Score: 0.007
  31. Kliem V, Wanner C, Eisenhauer T, Olbricht CJ, Doll R, Boddaert M, O'Grady P, Krekler M, Mangold B, Christians U. Comparison of pravastatin and lovastatin in renal transplant patients receiving cyclosporine. Transplant Proc. 1996 Dec; 28(6):3126-8.
    View in: PubMed
    Score: 0.007
  32. Christians U, Bleck JS, Lampen A, Bader A, Thiesemann C, Kliem V, Repp H, Westhoff-Bleck M, Manns M, Sewing KF. Are cytochrome P450 3A enzymes in the small intestine responsible for different cyclosporine metabolite patterns in stable male and female renal allograft recipients after co-administration of diltiazem? Transplant Proc. 1996 Aug; 28(4):2159-61.
    View in: PubMed
    Score: 0.007
  33. Christians U, Kohlhaw K, S?rig T, Bader A, Schottmann R, Linck A, Ringe B, Sewing KF. Parallel blood concentrations of second-generation cyclosporine metabolites and bilirubin in liver graft recipients. Ther Drug Monit. 1995 Oct; 17(5):487-98.
    View in: PubMed
    Score: 0.006
  34. Emoto C, Fukuda T, Mizuno T, Cox S, Schniedewind B, Christians U, Widemann BC, Fisher MJ, Weiss B, Perentesis J, Vinks AA. Age-dependent changes in sirolimus metabolite formation in patients with neurofibromatosis type 1. Ther Drug Monit. 2015 Jun; 37(3):395-9.
    View in: PubMed
    Score: 0.006
  35. Klawitter J, Reed-Gitomer BY, McFann K, Pennington A, Klawitter J, Abebe KZ, Klepacki J, Cadnapaphornchai MA, Brosnahan G, Chonchol M, Christians U, Schrier RW. Endothelial dysfunction and oxidative stress in polycystic kidney disease. Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1198-206.
    View in: PubMed
    Score: 0.006
  36. Gardner LA, Klawitter J, Gregory MA, Zaberezhnyy V, Baturin D, Pollyea DA, Takebe N, Christians U, Gore L, DeGregori J, Porter CC. Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia. Am J Hematol. 2014 Sep; 89(9):896-903.
    View in: PubMed
    Score: 0.006
  37. Klawitter J, Klawitter J, McFann K, Pennington AT, Abebe KZ, Brosnahan G, Cadnapaphornchai MA, Chonchol M, Gitomer B, Christians U, Schrier RW. Bioactive lipid mediators in polycystic kidney disease. J Lipid Res. 2014 06; 55(6):1139-49.
    View in: PubMed
    Score: 0.006
  38. Frassetto L, Floren L, Barin B, Browne M, Wolfe A, Roland M, Stock P, Carlson L, Christians U, Benet L. Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients. Biopharm Drug Dispos. 2013 Nov; 34(8):442-51.
    View in: PubMed
    Score: 0.006
  39. Ogasawara K, Chitnis SD, Gohh RY, Christians U, Akhlaghi F. Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipients. Clin Pharmacokinet. 2013 Sep; 52(9):751-62.
    View in: PubMed
    Score: 0.006
  40. Christians U, Spiekermann K, Bader A, Schottmann R, Linck A, Wonigeit K, Sewing KF, Link H. Cyclosporine metabolite pattern in blood from patients with acute GVHD after BMT. Bone Marrow Transplant. 1993 Jul; 12(1):27-33.
    View in: PubMed
    Score: 0.005
  41. Klepacki J, Brunner N, Schmitz V, Klawitter J, Christians U, Klawitter J. Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma. Clin Chim Acta. 2013 Jun 05; 421:91-7.
    View in: PubMed
    Score: 0.005
  42. Chitnis SD, Ogasawara K, Schniedewind B, Gohh RY, Christians U, Akhlaghi F. Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism. Xenobiotica. 2013 Jul; 43(7):641-9.
    View in: PubMed
    Score: 0.005
  43. Aquilante CL, Kiser JJ, Anderson PL, Christians U, Kosmiski LA, Daily EB, Hoffman KL, Hopley CW, Predhomme JA, Schniedewind B, Sidhom MS. Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin. J Clin Pharmacol. 2012 Nov; 52(11):1725-38.
    View in: PubMed
    Score: 0.005
  44. Christians U, Kohlhaw K, Budniak J, Bleck JS, Schottmann R, Schlitt HJ, Almeida VM, Deters M, Wonigeit K, Pichlmayr R, et al. Ciclosporin metabolite pattern in blood and urine of liver graft recipients. I. Association of ciclosporin metabolites with nephrotoxicity. Eur J Clin Pharmacol. 1991; 41(4):285-90.
    View in: PubMed
    Score: 0.005
  45. Angst MS, Phillips NG, Drover DR, Tingle M, Galinkin JL, Christians U, Swan GE, Lazzeroni LC, Clark JD. Opioid pharmacogenomics using a twin study paradigm: methods and procedures for determining familial aggregation and heritability. Twin Res Hum Genet. 2010 Oct; 13(5):412-25.
    View in: PubMed
    Score: 0.005
  46. Thethi TK, Rao A, Kawji H, Mallik T, Yau CL, Christians U, Fonseca V. Consequences of delayed pump infusion line change in patients with type 1 diabetes mellitus treated with continuous subcutaneous insulin infusion. J Diabetes Complications. 2010 Mar-Apr; 24(2):73-8.
    View in: PubMed
    Score: 0.004
  47. Tissot van Patot MC, Serkova NJ, Haschke M, Kominsky DJ, Roach RC, Christians U, Henthorn TK, Honigman B. Enhanced leukocyte HIF-1alpha and HIF-1 DNA binding in humans after rapid ascent to 4300 m. Free Radic Biol Med. 2009 Jun 01; 46(11):1551-7.
    View in: PubMed
    Score: 0.004
  48. Perry TW, Christians U, Trotter JF, Bendrick-Peart J. Pharmacokinetics of enteric-coated mycophenolate sodium in stable liver transplant recipients. Clin Transplant. 2007 May-Jun; 21(3):413-6.
    View in: PubMed
    Score: 0.004
  49. Frassetto L, Baluom M, Jacobsen W, Christians U, Roland ME, Stock PG, Carlson L, Benet LZ. Cyclosporine pharmacokinetics and dosing modifications in human immunodeficiency virus-infected liver and kidney transplant recipients. Transplantation. 2005 Jul 15; 80(1):13-7.
    View in: PubMed
    Score: 0.003
  50. Tissot van Patot MC, Leadbetter G, Keyes LE, Bendrick-Peart J, Beckey VE, Christians U, Hackett P. Greater free plasma VEGF and lower soluble VEGF receptor-1 in acute mountain sickness. J Appl Physiol (1985). 2005 May; 98(5):1626-9.
    View in: PubMed
    Score: 0.003
  51. Tsunoda SM, Harris RZ, Christians U, Velez RL, Freeman RB, Benet LZ, Warshaw A. Red wine decreases cyclosporine bioavailability. Clin Pharmacol Ther. 2001 Nov; 70(5):462-7.
    View in: PubMed
    Score: 0.002
  52. Winkler M, Haller G, Oldhafer K, Bechstein WO, Kattner A, Maib?cher A, F?rber L, Ringe B, Christians U, Neuhaus P, Pichlmayr R. A new oral formulation of cyclosporine for early oral immunosuppressive therapy in liver transplant recipients. Transplantation. 1996 Oct 27; 62(8):1063-8.
    View in: PubMed
    Score: 0.002
  53. Gonschior AK, Christians U, Winkler M, Linck A, Baumann J, Sewing KF. Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. Clin Chem. 1996 Sep; 42(9):1426-32.
    View in: PubMed
    Score: 0.002
  54. Bleck JS, Thiesemann C, Kliem V, Christians U, Hecker H, Repp H, Frei U, Westhoff-Bleck M, Manns M, Sewing KF. Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients. Br J Clin Pharmacol. 1996 Jun; 41(6):551-6.
    View in: PubMed
    Score: 0.002
  55. Lampen A, Christians U, Bader A, Hackbarth I, Sewing KF. Drug interactions and interindividual variability of ciclosporin metabolism in the small intestine. Pharmacology. 1996 Mar; 52(3):159-68.
    View in: PubMed
    Score: 0.002
  56. Gonschior AK, Christians U, Braun F, Winkler M, Linck A, Baumann J, Sewing KF. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA). Br J Clin Pharmacol. 1994 Dec; 38(6):567-71.
    View in: PubMed
    Score: 0.002
  57. Kohlhaw K, Christians U, S?rig T, Lamesch P, Hauss J, Sewing KF, Pichlmayr R. Cyclosporine and bilirubin metabolites compete for the hepatic excretory system. Transplant Proc. 1994 Oct; 26(5):2798-9.
    View in: PubMed
    Score: 0.001
  58. Bader A, Zech K, Crome O, Christians U, Ringe B, Pichlmayr R, Sewing KF. Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals. Xenobiotica. 1994 Jul; 24(7):623-33.
    View in: PubMed
    Score: 0.001
  59. Sewing KF, Christians U, Kohlhaw K, Radeke H, Strohmeyer S, Kownatzki R, Budniak J, Schottmann R, Bleck JS, Almeida VM, et al. Biologic activity of cyclosporine metabolites. Transplant Proc. 1990 Jun; 22(3):1129-34.
    View in: PubMed
    Score: 0.001
  60. Bleck JS, Nashan B, Christians U, Schottmann R, Wonigeit K, Sewing KF. Single dose pharmacokinetics of ciclosporin and its main metabolites after oral ciclosporin as oily solution or capsule. Arzneimittelforschung. 1990 Jan; 40(1):62-4.
    View in: PubMed
    Score: 0.001
  61. Bleck JS, Schlitt HJ, Christians U, Thiesemann C, Strohmeyer S, Schottmann R, Kohlhaw K, Wonigeit K, Sewing KF. Urinary excretion of ciclosporin and 17 of its metabolites in renal allograft recipients. Pharmacology. 1989; 39(3):160-4.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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