 Connection
Uwe Christians to Biotransformation
This is a "connection" page, showing publications Uwe Christians has written about Biotransformation.
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Connection Strength |
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0.284 |
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van Hoogdalem MW, Johnson TN, McPhail BT, Kamatkar S, Wexelblatt SL, Ward LP, Christians U, Akinbi HT, Vinks AA, Mizuno T. Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome. Clin Pharmacol Ther. 2022 02; 111(2):496-508.
Score: 0.047
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Jacobsen W, Kirchner G, Hallensleben K, Mancinelli L, Deters M, Hackbarth I, Benet LZ, Sewing KF, Christians U. Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver. Drug Metab Dispos. 1999 Feb; 27(2):173-9.
Score: 0.039
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Sperschneider H, Wagner C, Korn A, Christians U. [Effect of diltiazem on concentration of cyclosporin metabolites in Sandimmune and Neoral treated kidney transplant patients]. Med Klin (Munich). 1997 Oct 15; 92(10):589-96.
Score: 0.035
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Christians U, Strohmeyer S, Kownatzki R, Schiebel HM, Bleck J, Greipel J, Kohlhaw K, Schottmann R, Sewing KF. Investigations on the metabolic pathways of cyclosporine: I. Excretion of cyclosporine and its metabolites in human bile--isolation of 12 new cyclosporine metabolites. Xenobiotica. 1991 Sep; 21(9):1185-98.
Score: 0.023
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Christians U, Zimmer KO, Wonigeit K, Sewing KF. Measurement of cyclosporin A and of four metabolites in whole blood by high-performance liquid chromatography. J Chromatogr. 1987 Jan 23; 413:121-9.
Score: 0.017
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Schmelzer E, Acikgoez A, Fr?hauf NR, Crome O, Klempnauer J, Christians U, Bader A. Biotransformation of cyclosporin in primary rat, porcine and human liver cell co-cultures. Xenobiotica. 2006 Aug; 36(8):693-708.
Score: 0.016
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Kirchner G, Mueller L, Winkler M, Loss M, Roechte F, Deters M, Christians U, Kaever V, Klempnauer J, Sewing K, Manns M. Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients. Transplant Proc. 2002 Sep; 34(6):2233-4.
Score: 0.012
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Kuhn B, Jacobsen W, Christians U, Benet LZ, Kollman PA. Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: insights from docking, molecular dynamics, and quantum chemical calculations. J Med Chem. 2001 Jun 07; 44(12):2027-34.
Score: 0.011
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Braun F, Christians U, Laabs S, Elias K, Shipkova M, Sch?tz E, Ringe B. An ex vivo model to study the intestinal biotransformation of immunosuppressive drugs. Transplant Proc. 2000 Nov; 32(7):1999.
Score: 0.011
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Braun F, Christians U, Laabs S, Elias K, Shipkova M, Sch?tz E, Ringe B. An ex vivo model to study the intestinal biotransformation of immunosuppressives. Transplant Proc. 2000 Nov; 32(7):2536.
Score: 0.011
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Hausen B, Boeke K, Berry GJ, Gummert JF, Christians U, Morris RE. Potentiation of immunosuppressive efficacy by combining the novel leflunomide analog, HMR 279, with microemulsion cyclosporine in a rat lung transplant model. Transplantation. 1999 Feb 15; 67(3):354-9.
Score: 0.010
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Bader A, Knop E, B?ker KH, Crome O, Fr?hauf N, Gonschior AK, Christians U, Esselmann H, Pichlmayr R, Sewing KF. Tacrolimus (FK 506) biotransformation in primary rat hepatocytes depends on extracellular matrix geometry. Naunyn Schmiedebergs Arch Pharmacol. 1996 Mar; 353(4):461-73.
Score: 0.008
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Lampen A, Christians U, Guengerich FP, Watkins PB, Kolars JC, Bader A, Gonschior AK, Dralle H, Hackbarth I, Sewing KF. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos. 1995 Dec; 23(12):1315-24.
Score: 0.008
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Bader A, Knop E, Fr?hauf N, Crome O, B?ker K, Christians U, Oldhafer K, Ringe B, Pichlmayr R, Sewing KF. Reconstruction of liver tissue in vitro: geometry of characteristic flat bed, hollow fiber, and spouted bed bioreactors with reference to the in vivo liver. Artif Organs. 1995 Sep; 19(9):941-50.
Score: 0.008
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Gonschior AK, Christians U, Braun F, Winkler M, Linck A, Baumann J, Sewing KF. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA). Br J Clin Pharmacol. 1994 Dec; 38(6):567-71.
Score: 0.007
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Bader A, Zech K, Crome O, Christians U, Ringe B, Pichlmayr R, Sewing KF. Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals. Xenobiotica. 1994 Jul; 24(7):623-33.
Score: 0.007
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Winkler M, Christians U, Stoll K, Baumann J, Pichlmayr R. Comparison of different assays for the quantitation of FK 506 levels in blood or plasma. Ther Drug Monit. 1994 Jun; 16(3):281-6.
Score: 0.007
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Sattler M, Guengerich FP, Yun CH, Christians U, Sewing KF. Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab Dispos. 1992 Sep-Oct; 20(5):753-61.
Score: 0.006
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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