Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.
 Back to Details

Connection

Uwe Christians to Mass Spectrometry

This is a "connection" page, showing publications Uwe Christians has written about Mass Spectrometry.

 
Connection Strength
  
 
 
1.844
  
  1. Christians U, Klawitter J, Hornberger A, Klawitter J. How unbiased is non-targeted metabolomics and is targeted pathway screening the solution? Curr Pharm Biotechnol. 2011 Jul; 12(7):1053-66.
    View in: PubMed
    Score: 0.282
  2. Strom T, Shokati T, Klawitter J, Klawitter J, Hoffman K, Schiebel HM, Christians U. Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns. J Mass Spectrom. 2011 Jul; 46(7):615-24.
    View in: PubMed
    Score: 0.282
  3. Sempio C, Klawitter J, Jackson M, Freni F, Shillingburg R, Hutchison K, Bidwell LC, Christians U, Klawitter J. Analysis of 14 endocannabinoids and endocannabinoid congeners in human plasma using column switching high-performance atmospheric pressure chemical ionization liquid chromatography-mass spectrometry. Anal Bioanal Chem. 2021 May; 413(12):3381-3392.
    View in: PubMed
    Score: 0.139
  4. Christians U, Jacobsen W, Serkova N, Benet LZ, Vidal C, Sewing KF, Manns MP, Kirchner GI. Automated, fast and sensitive quantification of drugs in blood by liquid chromatography-mass spectrometry with on-line extraction: immunosuppressants. J Chromatogr B Biomed Sci Appl. 2000 Oct 01; 748(1):41-53.
    View in: PubMed
    Score: 0.134
  5. Shokati T, Hartmann M, Davari B, Klawitter J, Klawitter J, Christians U. Temsirolimus metabolic pathways revisited. Xenobiotica. 2020 Jun; 50(6):640-653.
    View in: PubMed
    Score: 0.125
  6. Segarra I, Brazelton TR, Guterman N, Hausen B, Jacobsen W, Morris RE, Benet LZ, Christians U. Development of a high-performance liquid chromatographic-electrospray mass spectrometric assay for the specific and sensitive quantification of the novel immunosuppressive macrolide 40-O-(2-hydroxyethyl)rapamycin. J Chromatogr B Biomed Sci Appl. 1998 Dec 11; 720(1-2):179-87.
    View in: PubMed
    Score: 0.118
  7. Heischmann S, Dzieciatkowska M, Hansen K, Leibfritz D, Christians U. The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model. Sci Rep. 2017 03 22; 7:45088.
    View in: PubMed
    Score: 0.105
  8. Klawitter J, Bek S, Zakaria M, Zeng C, Hornberger A, Gilbert R, Shokati T, Klawitter J, Christians U, Boernsen KO. Fatty acid desaturation index in human plasma: comparison of different analytical methodologies for the evaluation of diet effects. Anal Bioanal Chem. 2014 Oct; 406(25):6399-408.
    View in: PubMed
    Score: 0.087
  9. F?ste CK, R?nning HT, Christians U, Granum PE. Liquid chromatography and mass spectrometry in food allergen detection. J Food Prot. 2011 Feb; 74(2):316-45.
    View in: PubMed
    Score: 0.069
  10. Klawitter J, Haschke M, Kahle C, Dingmann C, Klawitter J, Leibfritz D, Christians U. Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose. Br J Clin Pharmacol. 2010 Aug; 70(2):241-51.
    View in: PubMed
    Score: 0.066
  11. Faeste CK, Christians U, Egaas E, Jonscher KR. Characterization of potential allergens in fenugreek (Trigonella foenum-graecum) using patient sera and MS-based proteomic analysis. J Proteomics. 2010 May 07; 73(7):1321-33.
    View in: PubMed
    Score: 0.064
  12. Strom T, Haschke M, Zhang YL, Bendrick-Peart J, Boyd J, Roberts M, Arabshahi L, Marbach P, Christians U. Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients. Ther Drug Monit. 2007 Oct; 29(5):592-9.
    View in: PubMed
    Score: 0.054
  13. Soldner A, Benet LZ, Mutschler E, Christians U. Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and caco-2 cell monolayers. Br J Pharmacol. 2000 Mar; 129(6):1235-43.
    View in: PubMed
    Score: 0.032
  14. Serkova N, Litt L, Leibfritz D, Hausen B, Morris RE, James TL, Benet LZ, Christians U. The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates. Br J Pharmacol. 2000 Feb; 129(3):485-92.
    View in: PubMed
    Score: 0.032
  15. Serkova N, Litt L, James TL, Sad?e W, Leibfritz D, Benet LZ, Christians U. Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy. J Pharmacol Exp Ther. 1999 May; 289(2):800-6.
    View in: PubMed
    Score: 0.030
  16. Gonschior AK, Christians U, Winkler M, Schiebel HM, Linck A, Sewing KF. Simplified high-performance liquid chromatography-mass spectrometry assay for measurement of tacrolimus and its metabolites and cross-validation with microparticle enzyme immunoassay. Ther Drug Monit. 1995 Oct; 17(5):504-10.
    View in: PubMed
    Score: 0.024
  17. Christians U, Braun F, Schmidt M, Kosian N, Schiebel HM, Ernst L, Winkler M, Kruse C, Linck A, Sewing KF. Specific and sensitive measurement of FK506 and its metabolites in blood and urine of liver-graft recipients. Clin Chem. 1992 Oct; 38(10):2025-32.
    View in: PubMed
    Score: 0.019
  18. Klawitter J, Klawitter J, Agardi E, Corby K, Leibfritz D, Lowes BD, Christians U, Seres T. Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy. Cardiovasc Res. 2013 Jan 01; 97(1):66-76.
    View in: PubMed
    Score: 0.019
  19. Christians U, Braun F, Kosian N, Schmidt M, Schiebel HM, Ernst L, Kruse C, Winkler M, Holze I, Linck A, et al. High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. Transplant Proc. 1991 Dec; 23(6):2741-4.
    View in: PubMed
    Score: 0.018
  20. Christians U, Strohmeyer S, Kownatzki R, Schiebel HM, Bleck J, Greipel J, Kohlhaw K, Schottmann R, Sewing KF. Investigations on the metabolic pathways of cyclosporine: I. Excretion of cyclosporine and its metabolites in human bile--isolation of 12 new cyclosporine metabolites. Xenobiotica. 1991 Sep; 21(9):1185-98.
    View in: PubMed
    Score: 0.018
  21. Christians U, Strohmeyer S, Kownatzki R, Schiebel HM, Bleck J, Kohlhaw K, Schottmann R, Sewing KF. Investigations on the metabolic pathways of cyclosporine: II. Elucidation of the metabolic pathways in vitro by human liver microsomes. Xenobiotica. 1991 Sep; 21(9):1199-210.
    View in: PubMed
    Score: 0.018
  22. Klawitter J, Shokati T, Moll V, Christians U, Klawitter J. Effects of lovastatin on breast cancer cells: a proteo-metabonomic study. Breast Cancer Res. 2010; 12(2):R16.
    View in: PubMed
    Score: 0.016
  23. Christians U, Schlitt HJ, Bleck JS, Schiebel HM, Kownatzki R, Maurer G, Strohmeyer SS, Schottmann R, Wonigeit K, Pichlmayr R, et al. Measurement of cyclosporine and 18 metabolites in blood, bile, and urine by high-performance liquid chromatography. Transplant Proc. 1988 Apr; 20(2 Suppl 2):609-13.
    View in: PubMed
    Score: 0.014
  24. Zhou H, Zhang Y, Biggs DL, Manning MC, Randolph TW, Christians U, Hybertson BM, Ng KY. Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages. J Control Release. 2005 Oct 03; 107(2):288-99.
    View in: PubMed
    Score: 0.012
  25. Jacobsen W, Christians U, Benet LZ. In vitro evaluation of the disposition of A novel cysteine protease inhibitor. Drug Metab Dispos. 2000 Nov; 28(11):1343-51.
    View in: PubMed
    Score: 0.008
  26. Kirchner GI, Vidal C, Jacobsen W, Franzke A, Hallensleben K, Christians U, Sewing KF. Simultaneous on-line extraction and analysis of sirolimus (rapamycin) and ciclosporin in blood by liquid chromatography-electrospray mass spectrometry. J Chromatogr B Biomed Sci Appl. 1999 Jan 22; 721(2):285-94.
    View in: PubMed
    Score: 0.007
  27. Braun F, Sch?tz E, Christians U, Lorf T, Schiffmann JH, Armstrong VW, Schr?ter W, Sewing KF, Oellerich M, Ringe B. Pitfalls in monitoring tacrolimus (FK 506). Ther Drug Monit. 1997 Dec; 19(6):628-31.
    View in: PubMed
    Score: 0.007
  28. Braun F, Lorf T, Sch?tz E, Christians U, Grupp C, Sattler B, Canelo R, Sewing KF, Armstrong VW, Oellerich M, Ringe B. Clinical relevance of monitoring tacrolimus: comparison of microparticle enzyme immunoassay, enzyme-linked immunosorbent assay, and liquid chromatography mass spectrometry in renal transplant recipients converted from cyclosporine to tacrolimus. Transplant Proc. 1996 Dec; 28(6):3175-6.
    View in: PubMed
    Score: 0.006
  29. Streit F, Christians U, Schiebel HM, Meyer A, Sewing KF. Structural identification of three metabolites and a degradation product of the macrolide immunosuppressant sirolimus (rapamycin) by electrospray-MS/MS after incubation with human liver microsomes. Drug Metab Dispos. 1996 Nov; 24(11):1272-8.
    View in: PubMed
    Score: 0.006
  30. Streit F, Christians U, Schiebel HM, Napoli KL, Ernst L, Linck A, Kahan BD, Sewing KF. Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry. Clin Chem. 1996 Sep; 42(9):1417-25.
    View in: PubMed
    Score: 0.006
  31. Gonschior AK, Christians U, Winkler M, Linck A, Baumann J, Sewing KF. Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. Clin Chem. 1996 Sep; 42(9):1426-32.
    View in: PubMed
    Score: 0.006
  32. Althaus C, Dagres E, Reinhard T, Christians U, Sundmacher R. Cyclosporin-A and its metabolites in the anterior chamber after topical and systemic application as determined with high-performance liquid chromatography-electrospray mass spectrometry. Ger J Ophthalmol. 1996 Jul; 5(4):189-94.
    View in: PubMed
    Score: 0.006
  33. Lampen A, Christians U, Guengerich FP, Watkins PB, Kolars JC, Bader A, Gonschior AK, Dralle H, Hackbarth I, Sewing KF. Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability. Drug Metab Dispos. 1995 Dec; 23(12):1315-24.
    View in: PubMed
    Score: 0.006
  34. Gonschior AK, Christians U, Braun F, Winkler M, Linck A, Baumann J, Sewing KF. Measurement of blood concentrations of FK506 (tacrolimus) and its metabolites in seven liver graft patients after the first dose by h.p.l.c.-MS and microparticle enzyme immunoassay (MEIA). Br J Clin Pharmacol. 1994 Dec; 38(6):567-71.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)