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Connection

Uwe Christians to Kidney Transplantation

This is a "connection" page, showing publications Uwe Christians has written about Kidney Transplantation.

 
Connection Strength
  
 
 
3.558
  
  1. Klawitter J, Kirkpatrick BE, Shillingburg R, Klawitter J, Wheeler G, Shokati T, Cadnapaphornchai MA, Galinkin JL, Thurman JM, Christians U. Monitoring of Allograft Adaptation After Kidney Transplantation in Pediatric Patients by Targeted Plasma Metabolomics. Int J Mol Sci. 2025 Sep 20; 26(18).
    View in: PubMed
    Score: 0.579
  2. Alloway RR, Vinks AA, Fukuda T, Mizuno T, King EC, Zou Y, Jiang W, Woodle ES, Tremblay S, Klawitter J, Klawitter J, Christians U. Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial. PLoS Med. 2017 Nov; 14(11):e1002428.
    View in: PubMed
    Score: 0.336
  3. Bohra R, Klepacki J, Klawitter J, Klawitter J, Thurman JM, Christians U. Proteomics and metabolomics in renal transplantation-quo vadis? Transpl Int. 2013 Mar; 26(3):225-41.
    View in: PubMed
    Score: 0.238
  4. Christians U, Klawitter J, Klawitter J, Brunner N, Schmitz V. Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions. Expert Opin Drug Metab Toxicol. 2011 Feb; 7(2):175-200.
    View in: PubMed
    Score: 0.210
  5. Schmitz V, Klawitter J, Bendrick-Peart J, Schoening W, Puhl G, Haschke M, Klawitter J, Consoer J, Rivard CJ, Chan L, Tran ZV, Leibfritz D, Christians U. Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation. Nephron Exp Nephrol. 2009; 111(4):e80-91.
    View in: PubMed
    Score: 0.184
  6. Filler G, Bendrick-Peart J, Strom T, Zhang YL, Johnson G, Christians U. Characterization of sirolimus metabolites in pediatric solid organ transplant recipients. Pediatr Transplant. 2009 Feb; 13(1):44-53.
    View in: PubMed
    Score: 0.174
  7. Strom T, Haschke M, Zhang YL, Bendrick-Peart J, Boyd J, Roberts M, Arabshahi L, Marbach P, Christians U. Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients. Ther Drug Monit. 2007 Oct; 29(5):592-9.
    View in: PubMed
    Score: 0.167
  8. Filler G, de Barros VR, Jagger JE, Christians U. Cyclosporin twice or three times daily dosing in pediatric transplant patients - it is not the same! Pediatr Transplant. 2006 Dec; 10(8):953-6.
    View in: PubMed
    Score: 0.157
  9. Filler G, Womiloju T, Feber J, Lepage N, Christians U. Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure. Am J Transplant. 2005 Aug; 5(8):2005-10.
    View in: PubMed
    Score: 0.143
  10. Leino AD, King EC, Jiang W, Vinks AA, Klawitter J, Christians U, Woodle ES, Alloway RR, Rohan JM. Assessment of tacrolimus intrapatient variability in stable adherent transplant recipients: Establishing baseline values. Am J Transplant. 2019 05; 19(5):1410-1420.
    View in: PubMed
    Score: 0.091
  11. Sperschneider H, Wagner C, Korn A, Christians U. [Effect of diltiazem on concentration of cyclosporin metabolites in Sandimmune and Neoral treated kidney transplant patients]. Med Klin (Munich). 1997 Oct 15; 92(10):589-96.
    View in: PubMed
    Score: 0.084
  12. Olbricht C, Wanner C, Eisenhauer T, Kliem V, Doll R, Boddaert M, O'Grady P, Krekler M, Mangold B, Christians U. Accumulation of lovastatin, but not pravastatin, in the blood of cyclosporine-treated kidney graft patients after multiple doses. Clin Pharmacol Ther. 1997 Sep; 62(3):311-21.
    View in: PubMed
    Score: 0.083
  13. Diwan TS, Lichvar AB, Leino AD, Vinks AA, Christians U, Shields AR, Cardi MA, Fukuda T, Mizuno T, Kaiser T, Woodle ES, Alloway RR. Pharmacokinetic and pharmacogenetic analysis of immunosuppressive agents after laparoscopic sleeve gastrectomy. Clin Transplant. 2017 06; 31(6).
    View in: PubMed
    Score: 0.081
  14. Kliem V, Wanner C, Eisenhauer T, Olbricht CJ, Doll R, Boddaert M, O'Grady P, Krekler M, Mangold B, Christians U. Comparison of pravastatin and lovastatin in renal transplant patients receiving cyclosporine. Transplant Proc. 1996 Dec; 28(6):3126-8.
    View in: PubMed
    Score: 0.079
  15. Christians U, Bleck JS, Lampen A, Bader A, Thiesemann C, Kliem V, Repp H, Westhoff-Bleck M, Manns M, Sewing KF. Are cytochrome P450 3A enzymes in the small intestine responsible for different cyclosporine metabolite patterns in stable male and female renal allograft recipients after co-administration of diltiazem? Transplant Proc. 1996 Aug; 28(4):2159-61.
    View in: PubMed
    Score: 0.077
  16. Christians U, Klawitter J, Klawitter J. Biomarkers in Transplantation--Proteomics and Metabolomics. Ther Drug Monit. 2016 Apr; 38 Suppl 1:S70-4.
    View in: PubMed
    Score: 0.075
  17. Shihab F, Christians U, Smith L, Wellen JR, Kaplan B. Focus on mTOR inhibitors and tacrolimus in renal transplantation: pharmacokinetics, exposure-response relationships, and clinical outcomes. Transpl Immunol. 2014 Jun; 31(1):22-32.
    View in: PubMed
    Score: 0.066
  18. Klawitter J, Klawitter J, Schmitz V, Shokati T, Epshtein E, Thurman JM, Christians U. Mycophenolate mofetil enhances the negative effects of sirolimus and tacrolimus on rat kidney cell metabolism. PLoS One. 2014; 9(1):e86202.
    View in: PubMed
    Score: 0.065
  19. Ogasawara K, Chitnis SD, Gohh RY, Christians U, Akhlaghi F. Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipients. Clin Pharmacokinet. 2013 Sep; 52(9):751-62.
    View in: PubMed
    Score: 0.063
  20. Klepacki J, Brunner N, Schmitz V, Klawitter J, Christians U, Klawitter J. Development and validation of an LC-MS/MS assay for the quantification of the trans-methylation pathway intermediates S-adenosylmethionine and S-adenosylhomocysteine in human plasma. Clin Chim Acta. 2013 Jun 05; 421:91-7.
    View in: PubMed
    Score: 0.061
  21. Chitnis SD, Ogasawara K, Schniedewind B, Gohh RY, Christians U, Akhlaghi F. Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism. Xenobiotica. 2013 Jul; 43(7):641-9.
    View in: PubMed
    Score: 0.060
  22. Christians U, Schmitz V, Schöning W, Bendrick-Peart J, Klawitter J, Haschke M, Klawitter J. Toxicodynamic therapeutic drug monitoring of immunosuppressants: promises, reality, and challenges. Ther Drug Monit. 2008 Apr; 30(2):151-8.
    View in: PubMed
    Score: 0.043
  23. Schmitz V, Klawitter J, Bendrick-Peart J, Haschke M, Beckey VE, Laudi S, Neumann U, Schoening W, Neuhaus P, Christians U, Puhl G. Impact of organ preservation using HTK for graft flush and subsequent storage in UW in rat kidney transplantation. Eur Surg Res. 2006; 38(4):388-98.
    View in: PubMed
    Score: 0.038
  24. Frassetto L, Baluom M, Jacobsen W, Christians U, Roland ME, Stock PG, Carlson L, Benet LZ. Cyclosporine pharmacokinetics and dosing modifications in human immunodeficiency virus-infected liver and kidney transplant recipients. Transplantation. 2005 Jul 15; 80(1):13-7.
    View in: PubMed
    Score: 0.036
  25. Lam TT, Hausen B, Hook L, Lau M, Higgins J, Christians U, Jacobsen W, Baluom M, Duthaler R, Katopodis A, Chavez G, Cozzi E, Harrison R, Schuurman HJ, Borie D, Morris RE. The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF-transgenic pig-to-primate life-supporting kidney xenografts. Xenotransplantation. 2005 Jan; 12(1):20-9.
    View in: PubMed
    Score: 0.034
  26. Wiseman AC, Kam I, Christians U, Jani A, Bak T, Wachs M, Chan L. Fixed-dose sirolimus with reduced dose calcineurin inhibitor: the University of Colorado experience. Transplant Proc. 2003 May; 35(3 Suppl):122S-124S.
    View in: PubMed
    Score: 0.031
  27. Kirchner G, Mueller L, Winkler M, Loss M, Roechte F, Deters M, Christians U, Kaever V, Klempnauer J, Sewing K, Manns M. Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients. Transplant Proc. 2002 Sep; 34(6):2233-4.
    View in: PubMed
    Score: 0.029
  28. Hausen B, Klupp J, Christians U, Higgins JP, Baumgartner RE, Hook LE, Friedrich S, Celnicker A, Morris RE. Coadministration of either cyclosporine or steroids with humanized monoclonal antibodies against CD80 and CD86 successfully prolong allograft survival after life supporting renal transplantation in cynomolgus monkeys. Transplantation. 2001 Sep 27; 72(6):1128-37.
    View in: PubMed
    Score: 0.027
  29. Jalal D, Renner B, Laskowski J, Stites E, Cooper J, Valente K, You Z, Perrenoud L, Le Quintrec M, Muhamed I, Christians U, Klawitter J, Lindorfer MA, Taylor RP, Holers VM, Thurman JM. Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease. J Am Heart Assoc. 2018 07 13; 7(14).
    View in: PubMed
    Score: 0.022
  30. Christians U. Combination of pravastatin and cyclosporin in transplant patients. Clin Pharmacokinet. 1997 Feb; 32(2):173-4.
    View in: PubMed
    Score: 0.020
  31. Winkler M, Christians U, Baumann J, Gonschior AK, Wonigeit K, Pichlmayr R. Evaluation of the Pro-Trac tacrolimus monoclonal whole-blood enzyme-linked immunosorbent assay for monitoring of tacrolimus levels in patients after kidney, heart, and liver transplantation. Ther Drug Monit. 1996 Dec; 18(6):640-6.
    View in: PubMed
    Score: 0.020
  32. Braun F, Lorf T, Schütz E, Christians U, Grupp C, Sattler B, Canelo R, Sewing KF, Armstrong VW, Oellerich M, Ringe B. Clinical relevance of monitoring tacrolimus: comparison of microparticle enzyme immunoassay, enzyme-linked immunosorbent assay, and liquid chromatography mass spectrometry in renal transplant recipients converted from cyclosporine to tacrolimus. Transplant Proc. 1996 Dec; 28(6):3175-6.
    View in: PubMed
    Score: 0.020
  33. Meyer K, Fobker M, Christians U, Erren M, Sewing KF, Assmann G, Benninghoven A. Characterization of glucuronidated phase II metabolites of the immunosuppressant cyclosporine in urine of transplant patients using time-of-flight secondary-ion mass spectrometry. Drug Metab Dispos. 1996 Oct; 24(10):1151-4.
    View in: PubMed
    Score: 0.019
  34. Streit F, Christians U, Schiebel HM, Napoli KL, Ernst L, Linck A, Kahan BD, Sewing KF. Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in blood of kidney graft recipients by HPLC/electrospray-mass spectrometry. Clin Chem. 1996 Sep; 42(9):1417-25.
    View in: PubMed
    Score: 0.019
  35. Gonschior AK, Christians U, Winkler M, Linck A, Baumann J, Sewing KF. Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. Clin Chem. 1996 Sep; 42(9):1426-32.
    View in: PubMed
    Score: 0.019
  36. Bleck JS, Thiesemann C, Kliem V, Christians U, Hecker H, Repp H, Frei U, Westhoff-Bleck M, Manns M, Sewing KF. Diltiazem increases blood concentrations of cyclized cyclosporine metabolites resulting in different cyclosporine metabolite patterns in stable male and female renal allograft recipients. Br J Clin Pharmacol. 1996 Jun; 41(6):551-6.
    View in: PubMed
    Score: 0.019
  37. Winkler M, Wonigeit K, Undre N, Ringe B, Oldhafer K, Christians U, Pichlmayr R. Comparison of plasma vs whole blood as matrix for FK 506 drug level monitoring. Transplant Proc. 1995 Feb; 27(1):822-5.
    View in: PubMed
    Score: 0.017
  38. Renner B, Klawitter J, Goldberg R, McCullough JW, Ferreira VP, Cooper JE, Christians U, Thurman JM. Cyclosporine induces endothelial cell release of complement-activating microparticles. J Am Soc Nephrol. 2013 Nov; 24(11):1849-62.
    View in: PubMed
    Score: 0.016
  39. Frassetto L, Floren L, Barin B, Browne M, Wolfe A, Roland M, Stock P, Carlson L, Christians U, Benet L. Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients. Biopharm Drug Dispos. 2013 Nov; 34(8):442-51.
    View in: PubMed
    Score: 0.016
  40. Bleck JS, Schlitt HJ, Christians U, Schottmann R, Thiesemann C, Strohmeyer S, Kohlhaw K, Wonigeit K, Pichlmayr R, Sewing KF. Ciclosporin metabolite pattern in blood and urine of kidney graft patients in relation to liver function. Eur J Clin Pharmacol. 1991; 40(6):565-9.
    View in: PubMed
    Score: 0.013
  41. Christians U, Zimmer KO, Wonigeit K, Maurer G, Sewing KF. Liquid-chromatographic measurement of cyclosporin A and its metabolites in blood, bile, and urine. Clin Chem. 1988 Jan; 34(1):34-9.
    View in: PubMed
    Score: 0.011
  42. Gonschior AK, Christians U, Winkler M, Schiebel HM, Linck A, Sewing KF. Simplified high-performance liquid chromatography-mass spectrometry assay for measurement of tacrolimus and its metabolites and cross-validation with microparticle enzyme immunoassay. Ther Drug Monit. 1995 Oct; 17(5):504-10.
    View in: PubMed
    Score: 0.005
  43. Bleck JS, Nashan B, Christians U, Schottmann R, Wonigeit K, Sewing KF. Single dose pharmacokinetics of ciclosporin and its main metabolites after oral ciclosporin as oily solution or capsule. Arzneimittelforschung. 1990 Jan; 40(1):62-4.
    View in: PubMed
    Score: 0.003
  44. Bleck JS, Schlitt HJ, Christians U, Thiesemann C, Strohmeyer S, Schottmann R, Kohlhaw K, Wonigeit K, Sewing KF. Urinary excretion of ciclosporin and 17 of its metabolites in renal allograft recipients. Pharmacology. 1989; 39(3):160-4.
    View in: PubMed
    Score: 0.003
  45. Nashan B, Bleck J, Wonigeit K, Vogt P, Christians U, Sewing KF, Beveridge T, Pichlmayr R. Effect of the application form of cyclosporine on blood levels: comparison of oral solution and capsules. Transplant Proc. 1988 Apr; 20(2 Suppl 2):637-9.
    View in: PubMed
    Score: 0.003
  46. Sewing KF, Christians U, Bleck JS, Strohmeyer S, Beil W, Kohlhaw K, Wonigeit K. [Drug monitoring of cyclosporin by using high-performance liquid chromatography]. Dtsch Med Wochenschr. 1988 Feb 26; 113(8):311-4.
    View in: PubMed
    Score: 0.003
  47. Sewing KF, Christians U, Bleck JS, Schottmann R, Strohmeyer SS. Measurement and disposition of ciclosporin and its metabolites. Bibl Cardiol. 1988; (43):63-72.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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