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Connection

Kenneth MacLean to Mice

This is a "connection" page, showing publications Kenneth MacLean has written about Mice.

 
Connection Strength
 
 
 
0.744
 
  1. Maclean KN, Jiang H, Phinney WN, Mclagan BM, Roede JR, Stabler SP. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis. Mol Genet Metab. 2021 02; 132(2):128-138.
    View in: PubMed
    Score: 0.060
  2. Maclean KN, Jiang H, Phinney WN, Keating AK, Hurt KJ, Stabler SP. Taurine alleviates repression of betaine-homocysteine S-methyltransferase and significantly improves the efficacy of long-term betaine treatment in a mouse model of cystathionine ?-synthase-deficient homocystinuria. FASEB J. 2019 05; 33(5):6339-6353.
    View in: PubMed
    Score: 0.052
  3. Maclean KN, Jiang H, Aivazidis S, Kim E, Shearn CT, Harris PS, Petersen DR, Allen RH, Stabler SP, Roede JR. Taurine treatment prevents derangement of the hepatic ?-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism. FASEB J. 2018 03; 32(3):1265-1280.
    View in: PubMed
    Score: 0.048
  4. Jacobs RL, Jiang H, Kennelly JP, Orlicky DJ, Allen RH, Stabler SP, Maclean KN. Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria. Mol Genet Metab. 2017 04; 120(4):325-336.
    View in: PubMed
    Score: 0.046
  5. Jiang H, Stabler SP, Allen RH, Abman SH, Maclean KN. Altered hepatic sulfur metabolism in cystathionine ?-synthase-deficient homocystinuria: regulatory role of taurine on competing cysteine oxidation pathways. FASEB J. 2014 Sep; 28(9):4044-54.
    View in: PubMed
    Score: 0.038
  6. Maclean KN, Greiner LS, Evans JR, Sood SK, Lhotak S, Markham NE, Stabler SP, Allen RH, Austin RC, Balasubramaniam V, Jiang H. Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death. J Biol Chem. 2012 Sep 14; 287(38):31994-2005.
    View in: PubMed
    Score: 0.033
  7. Jiang H, Stabler SP, Allen RH, Maclean KN. Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes. Mol Genet Metab. 2012 Sep; 107(1-2):55-65.
    View in: PubMed
    Score: 0.033
  8. Maclean KN, Jiang H, Greiner LS, Allen RH, Stabler SP. Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk. Mol Genet Metab. 2012 Mar; 105(3):395-403.
    View in: PubMed
    Score: 0.032
  9. Gentile CL, Nivala AM, Gonzales JC, Pfaffenbach KT, Wang D, Wei Y, Jiang H, Orlicky DJ, Petersen DR, Pagliassotti MJ, Maclean KN. Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. Am J Physiol Regul Integr Comp Physiol. 2011 Dec; 301(6):R1710-22.
    View in: PubMed
    Score: 0.031
  10. Keating AK, Freehauf C, Jiang H, Brodsky GL, Stabler SP, Allen RH, Graham DK, Thomas JA, Van Hove JL, Maclean KN. Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria. Mol Genet Metab. 2011 Aug; 103(4):330-7.
    View in: PubMed
    Score: 0.030
  11. Maclean KN, Sikora J, Ko?ich V, Jiang H, Greiner LS, Kraus E, Krijt J, Overdier KH, Collard R, Brodsky GL, Meltesen L, Crnic LS, Allen RH, Stabler SP, Elleder M, Rozen R, Patterson D, Kraus JP. A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment. Mol Genet Metab. 2010 Oct-Nov; 101(2-3):153-62.
    View in: PubMed
    Score: 0.029
  12. Maclean KN, Sikora J, Ko?ich V, Jiang H, Greiner LS, Kraus E, Krijt J, Crnic LS, Allen RH, Stabler SP, Elleder M, Kraus JP. Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment. Mol Genet Metab. 2010 Oct-Nov; 101(2-3):163-71.
    View in: PubMed
    Score: 0.029
  13. Nielsen DM, Evans JJ, Derber WJ, Johnston KA, Laudenslager ML, Crnic LS, Maclean KN. Mouse model of fragile X syndrome: behavioral and hormonal response to stressors. Behav Neurosci. 2009 Jun; 123(3):677-86.
    View in: PubMed
    Score: 0.027
  14. Brodsky GL, Bowersox JA, Fitzgerald-Miller L, Miller LA, Maclean KN. The prelamin A pre-peptide induces cardiac and skeletal myoblast differentiation. Biochem Biophys Res Commun. 2007 May 18; 356(4):872-9.
    View in: PubMed
    Score: 0.023
  15. Yousof TR, Bouchard CC, Alb M, Lynn EG, Lhot?k S, Jiang H, MacDonald M, Li H, Byun JH, Makda Y, Athanasopoulos M, Maclean KN, Cherrington NJ, Naqvi A, Igdoura SA, Krepinsky JC, Steinberg GR, Austin RC. Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice. J Biol Chem. 2024 02; 300(2):105655.
    View in: PubMed
    Score: 0.018
  16. Gupta S, Wang L, Slifker MJ, Cai KQ, Maclean KN, Wasek B, Bottiglieri T, Kruger WD. Analysis of differential neonatal lethality in cystathionine ?-synthase deficient mouse models using metabolic profiling. FASEB J. 2021 06; 35(6):e21629.
    View in: PubMed
    Score: 0.015
  17. Bok R, Guerra DD, Lorca RA, Wennersten SA, Harris PS, Rauniyar AK, Stabler SP, MacLean KN, Roede JR, Brown LD, Hurt KJ. Cystathionine ?-lyase promotes estrogen-stimulated uterine artery blood flow via glutathione homeostasis. Redox Biol. 2021 04; 40:101827.
    View in: PubMed
    Score: 0.015
  18. Guerra DD, Bok R, Breen K, Vyas V, Jiang H, MacLean KN, Hurt KJ. Estrogen Regulates Local Cysteine Metabolism in Mouse Myometrium. Reprod Sci. 2021 01; 28(1):79-90.
    View in: PubMed
    Score: 0.015
  19. Platko K, Lebeau PF, Byun JH, Poon SV, Day EA, MacDonald ME, Holzapfel N, Mejia-Benitez A, Maclean KN, Krepinsky JC, Austin RC. GDF10 blocks hepatic PPAR? activation to protect against diet-induced liver injury. Mol Metab. 2019 09; 27:62-74.
    View in: PubMed
    Score: 0.013
  20. Eyring KR, Pedersen BS, Maclean KN, Stabler SP, Yang IV, Schwartz DA. Methylene-tetrahydrofolate reductase contributes to allergic airway disease. PLoS One. 2018; 13(1):e0190916.
    View in: PubMed
    Score: 0.012
  21. Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS One. 2016; 11(4):e0154152.
    View in: PubMed
    Score: 0.011
  22. Maclean KN, See CG, McKay IA, Bustin SA. The human immediate early gene BRF1 maps to chromosome 14q22-q24. Genomics. 1995 Nov 01; 30(1):89-90.
    View in: PubMed
    Score: 0.010
  23. Galligan JJ, Fritz KS, Backos DS, Shearn CT, Smathers RL, Jiang H, MacLean KN, Reigan PR, Petersen DR. Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function. Free Radic Biol Med. 2014 Aug; 73:411-20.
    View in: PubMed
    Score: 0.009
  24. Hossain GS, Lynn EG, Maclean KN, Zhou J, Dickhout JG, Lhot?k S, Trigatti B, Capone J, Rho J, Tang D, McCulloch CA, Al-Bondokji I, Malloy MJ, Pullinger CR, Kane JP, Li Y, Shiffman D, Austin RC. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc. 2013 May 17; 2(3):e000134.
    View in: PubMed
    Score: 0.009
  25. Shearn CT, Smathers RL, Jiang H, Orlicky DJ, Maclean KN, Petersen DR. Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis. J Nutr Biochem. 2013 Aug; 24(8):1436-45.
    View in: PubMed
    Score: 0.009
  26. Basseri S, Lhot?k S, Fullerton MD, Palanivel R, Jiang H, Lynn EG, Ford RJ, Maclean KN, Steinberg GR, Austin RC. Loss of TDAG51 results in mature-onset obesity, hepatic steatosis, and insulin resistance by regulating lipogenesis. Diabetes. 2013 Jan; 62(1):158-69.
    View in: PubMed
    Score: 0.008
  27. Rachubinski AL, Maclean KN, Evans JR, Bjugstad KB. Modulating cognitive deficits and tau accumulation in a mouse model of aging Down syndrome through neonatal implantation of neural progenitor cells. Exp Gerontol. 2012 Sep; 47(9):723-33.
    View in: PubMed
    Score: 0.008
  28. Rachubinski AL, Crowley SK, Sladek JR, Maclean KN, Bjugstad KB. Effects of neonatal neural progenitor cell implantation on adult neuroanatomy and cognition in the Ts65Dn model of Down syndrome. PLoS One. 2012; 7(4):e36082.
    View in: PubMed
    Score: 0.008
  29. Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, Yang G, Mani S, Garg SK, Banerjee R, Kaufman RJ, Maclean KN, Wang R, Austin RC. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012 Mar 02; 287(10):7603-14.
    View in: PubMed
    Score: 0.008
  30. de Souza FM, Busquet N, Blatner M, Maclean KN, Restrepo D. Galantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome. Sci Rep. 2011; 1:137.
    View in: PubMed
    Score: 0.008
  31. Kern DS, Maclean KN, Jiang H, Synder EY, Sladek JR, Bjugstad KB. Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn Down syndrome mice. Cell Transplant. 2011; 20(3):371-9.
    View in: PubMed
    Score: 0.007
  32. Moon J, Chen M, Gandhy SU, Strawderman M, Levitsky DA, Maclean KN, Strupp BJ. Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome. Behav Neurosci. 2010 Jun; 124(3):346-61.
    View in: PubMed
    Score: 0.007
  33. Mikael LG, Wang XL, Wu Q, Jiang H, Maclean KN, Rozen R. Hyperhomocysteinemia is associated with hypertriglyceridemia in mice with methylenetetrahydrofolate reductase deficiency. Mol Genet Metab. 2009 Sep-Oct; 98(1-2):187-94.
    View in: PubMed
    Score: 0.007
  34. McNaughton CH, Moon J, Strawderman MS, Maclean KN, Evans J, Strupp BJ. Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome. Behav Neurosci. 2008 Apr; 122(2):293-300.
    View in: PubMed
    Score: 0.006
  35. Schwahn BC, Wang XL, Mikael LG, Wu Q, Cohn J, Jiang H, Maclean KN, Rozen R. Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia. Atherosclerosis. 2007 Dec; 195(2):e100-7.
    View in: PubMed
    Score: 0.006
  36. Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis. Hepatology. 2007 May; 45(5):1108-17.
    View in: PubMed
    Score: 0.006
  37. Withington SL, Scott AN, Saunders DN, Lopes Floro K, Preis JI, Michalicek J, Maclean K, Sparrow DB, Barbera JP, Dunwoodie SL. Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta. Dev Biol. 2006 Jun 01; 294(1):67-82.
    View in: PubMed
    Score: 0.005
  38. P?rez-Mancera PA, Gonz?lez-Herrero I, Maclean K, Turner AM, Yip MY, S?nchez-Mart?n M, Garc?a JL, Robledo C, Flores T, Guti?rrez-Ad?n A, Pintado B, S?nchez-Garc?a I. SLUG (SNAI2) overexpression in embryonic development. Cytogenet Genome Res. 2006; 114(1):24-9.
    View in: PubMed
    Score: 0.005
  39. Bar-Or D, Curtis CG, Sullivan A, Rael LT, Thomas GW, Craun M, Bar-Or R, Maclean KN, Kraus JP. Plasma albumin cysteinylation is regulated by cystathionine beta-synthase. Biochem Biophys Res Commun. 2004 Dec 24; 325(4):1449-53.
    View in: PubMed
    Score: 0.005
  40. Nie XF, Maclean KN, Kumar V, McKay IA, Bustin SA. ERF-2, the human homologue of the murine Tis11d early response gene. Gene. 1995 Jan 23; 152(2):285-6.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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