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Connection

David Bentley to Transcription, Genetic

This is a "connection" page, showing publications David Bentley has written about Transcription, Genetic.

 
Connection Strength
 
 
 
7.378
 
  1. Hyder U, Bentley DL. The Promoter-Proximal Pause: A Decision Point Governing RNA Polymerase II Fate. Annu Rev Biochem. 2026 06; 95(1):221-246.
    View in: PubMed
    Score: 0.594
  2. Shenasa H, Bentley DL. Pre-mRNA splicing and its cotranscriptional connections. Trends Genet. 2023 09; 39(9):672-685.
    View in: PubMed
    Score: 0.489
  3. Saldi T, Riemondy K, Erickson B, Bentley DL. Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing. Mol Cell. 2021 04 15; 81(8):1789-1801.e5.
    View in: PubMed
    Score: 0.418
  4. Fong N, Saldi T, Sheridan RM, Cortazar MA, Bentley DL. RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction. Mol Cell. 2017 May 18; 66(4):546-557.e3.
    View in: PubMed
    Score: 0.322
  5. Saldi T, Cortazar MA, Sheridan RM, Bentley DL. Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing. J Mol Biol. 2016 06 19; 428(12):2623-2635.
    View in: PubMed
    Score: 0.299
  6. Bentley DL. The union of transcription and mRNA processing: 20 years of coupling. RNA. 2015 Apr; 21(4):569-70.
    View in: PubMed
    Score: 0.278
  7. Bentley DL. Coupling mRNA processing with transcription in time and space. Nat Rev Genet. 2014 03; 15(3):163-75.
    View in: PubMed
    Score: 0.257
  8. Perales R, Zhang L, Bentley D. Histone occupancy in vivo at the 601 nucleosome binding element is determined by transcriptional history. Mol Cell Biol. 2011 Aug; 31(16):3485-96.
    View in: PubMed
    Score: 0.214
  9. Kim H, Erickson B, Luo W, Seward D, Graber JH, Pollock DD, Megee PC, Bentley DL. Gene-specific RNA polymerase II phosphorylation and the CTD code. Nat Struct Mol Biol. 2010 Oct; 17(10):1279-86.
    View in: PubMed
    Score: 0.203
  10. Perales R, Bentley D. "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. Mol Cell. 2009 Oct 23; 36(2):178-91.
    View in: PubMed
    Score: 0.191
  11. Fong N, Ohman M, Bentley DL. Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing. Nat Struct Mol Biol. 2009 Sep; 16(9):916-22.
    View in: PubMed
    Score: 0.188
  12. Glover-Cutter K, Kim S, Espinosa J, Bentley DL. RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes. Nat Struct Mol Biol. 2008 Jan; 15(1):71-8.
    View in: PubMed
    Score: 0.168
  13. Luo W, Johnson AW, Bentley DL. The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model. Genes Dev. 2006 Apr 15; 20(8):954-65.
    View in: PubMed
    Score: 0.149
  14. Bird G, Fong N, Gatlin JC, Farabaugh S, Bentley DL. Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing. Mol Cell. 2005 Dec 09; 20(5):747-58.
    View in: PubMed
    Score: 0.146
  15. Finlay-Schultz J, Vinod Paul K, Erickson B, Fettig LM, Hastings BS, Johnson DL, Bentley DL, Kabos P, Sartorius CA. Maf1 cooperates with progesterone receptor to repress RNA polymerase III transcription of select tRNAs. Nucleic Acids Res. 2025 Oct 28; 53(20).
    View in: PubMed
    Score: 0.145
  16. Shenasa H, Fong N, Erickson B, Iosub IA, Ule J, Bentley DL. CAR-SPLASH identifies nascent pre-mRNA structures implicated in kinetic coupling and alternative splicing. Proc Natl Acad Sci U S A. 2025 Oct 07; 122(40):e2504034122.
    View in: PubMed
    Score: 0.144
  17. Zhang L, Schroeder S, Fong N, Bentley DL. Altered nucleosome occupancy and histone H3K4 methylation in response to 'transcriptional stress'. EMBO J. 2005 Jul 06; 24(13):2379-90.
    View in: PubMed
    Score: 0.141
  18. Bentley DL. Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. Curr Opin Cell Biol. 2005 Jun; 17(3):251-6.
    View in: PubMed
    Score: 0.141
  19. Erickson B, Fedoryshchak R, Fong N, Sheridan R, Larson KY, Saviola AJ, Mouilleron S, Hansen KC, Treisman R, Bentley DL. PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination. Cell Rep. 2025 May 27; 44(5):115564.
    View in: PubMed
    Score: 0.139
  20. Luo W, Bentley D. A ribonucleolytic rat torpedoes RNA polymerase II. Cell. 2004 Dec 29; 119(7):911-4.
    View in: PubMed
    Score: 0.136
  21. Blears D, Lou J, Fong N, Mitter R, Sheridan RM, He D, Dirac-Svejstrup AB, Bentley D, Svejstrup JQ. Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint. Mol Cell. 2024 Dec 19; 84(24):4790-4807.e11.
    View in: PubMed
    Score: 0.135
  22. Bird G, Zorio DA, Bentley DL. RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formation. Mol Cell Biol. 2004 Oct; 24(20):8963-9.
    View in: PubMed
    Score: 0.134
  23. Bentley DL. Multiple Forms and Functions of Premature Termination by RNA Polymerase II. J Mol Biol. 2025 Jan 01; 437(1):168743.
    View in: PubMed
    Score: 0.133
  24. Zorio DA, Bentley DL. The link between mRNA processing and transcription: communication works both ways. Exp Cell Res. 2004 May 15; 296(1):91-7.
    View in: PubMed
    Score: 0.131
  25. Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 10 06; 82(19):3632-3645.e4.
    View in: PubMed
    Score: 0.117
  26. Bentley D. The mRNA assembly line: transcription and processing machines in the same factory. Curr Opin Cell Biol. 2002 Jun; 14(3):336-42.
    View in: PubMed
    Score: 0.114
  27. Zorio DA, Bentley DL. Transcription elongation: the 'Foggy' is liftingellipsis. Curr Biol. 2001 Feb 20; 11(4):R144-6.
    View in: PubMed
    Score: 0.104
  28. Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, Tao L, DeRoy P, Clavette C, Nayak S, Damon LJ, Kaltheuner IH, Bunch H, Cantley LC, Geyer M, Iwasa J, Dowell RD, Bentley DL, Old WM, Taatjes DJ. Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription. Genes Dev. 2020 11 01; 34(21-22):1452-1473.
    View in: PubMed
    Score: 0.102
  29. Schroeder SC, Schwer B, Shuman S, Bentley D. Dynamic association of capping enzymes with transcribing RNA polymerase II. Genes Dev. 2000 Oct 01; 14(19):2435-40.
    View in: PubMed
    Score: 0.102
  30. Bentley D. Coupling RNA polymerase II transcription with pre-mRNA processing. Curr Opin Cell Biol. 1999 Jun; 11(3):347-51.
    View in: PubMed
    Score: 0.093
  31. Yankulov K, Bentley D. Transcriptional control: Tat cofactors and transcriptional elongation. Curr Biol. 1998 Jun 18; 8(13):R447-9.
    View in: PubMed
    Score: 0.087
  32. Saldi T, Fong N, Bentley DL. Transcription elongation rate affects nascent histone pre-mRNA folding and 3' end processing. Genes Dev. 2018 02 01; 32(3-4):297-308.
    View in: PubMed
    Score: 0.085
  33. McCracken S, Rosonina E, Fong N, Sikes M, Beyer A, O'Hare K, Shuman S, Bentley D. Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing. Cold Spring Harb Symp Quant Biol. 1998; 63:301-9.
    View in: PubMed
    Score: 0.084
  34. Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell Rep. 2017 08 01; 20(5):1173-1186.
    View in: PubMed
    Score: 0.082
  35. McCracken S, Fong N, Yankulov K, Ballantyne S, Pan G, Greenblatt J, Patterson SD, Wickens M, Bentley DL. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature. 1997 Jan 23; 385(6614):357-61.
    View in: PubMed
    Score: 0.079
  36. Yankulov KY, Pandes M, McCracken S, Bouchard D, Bentley DL. TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes. Mol Cell Biol. 1996 Jul; 16(7):3291-9.
    View in: PubMed
    Score: 0.076
  37. Blau J, Xiao H, McCracken S, O'Hare P, Greenblatt J, Bentley D. Three functional classes of transcriptional activation domain. Mol Cell Biol. 1996 May; 16(5):2044-55.
    View in: PubMed
    Score: 0.075
  38. Yankulov K, Yamashita K, Roy R, Egly JM, Bentley DL. The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. J Biol Chem. 1995 Oct 13; 270(41):23922-5.
    View in: PubMed
    Score: 0.072
  39. Bentley DL. Regulation of transcriptional elongation by RNA polymerase II. Curr Opin Genet Dev. 1995 Apr; 5(2):210-6.
    View in: PubMed
    Score: 0.069
  40. Yankulov K, Blau J, Purton T, Roberts S, Bentley DL. Transcriptional elongation by RNA polymerase II is stimulated by transactivators. Cell. 1994 Jun 03; 77(5):749-59.
    View in: PubMed
    Score: 0.066
  41. Roberts S, Purton T, Bentley DL. A protein-binding site in the c-myc promoter functions as a terminator of RNA polymerase II transcription. Genes Dev. 1992 Aug; 6(8):1562-74.
    View in: PubMed
    Score: 0.058
  42. Brannan K, Kim H, Erickson B, Glover-Cutter K, Kim S, Fong N, Kiemele L, Hansen K, Davis R, Lykke-Andersen J, Bentley DL. mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription. Mol Cell. 2012 May 11; 46(3):311-24.
    View in: PubMed
    Score: 0.056
  43. Roberts S, Bentley DL. Distinct modes of transcription read through or terminate at the c-myc attenuator. EMBO J. 1992 Mar; 11(3):1085-93.
    View in: PubMed
    Score: 0.056
  44. Bentley DL, Brown WL, Groudine M. Accurate, TATA box-dependent polymerase III transcription from promoters of the c-myc gene in injected Xenopus oocytes. Genes Dev. 1989 Aug; 3(8):1179-89.
    View in: PubMed
    Score: 0.047
  45. Bentley DL, Groudine M. Sequence requirements for premature termination of transcription in the human c-myc gene. Cell. 1988 Apr 22; 53(2):245-56.
    View in: PubMed
    Score: 0.043
  46. Tassone F, Beilina A, Carosi C, Albertosi S, Bagni C, Li L, Glover K, Bentley D, Hagerman PJ. Elevated FMR1 mRNA in premutation carriers is due to increased transcription. RNA. 2007 Apr; 13(4):555-62.
    View in: PubMed
    Score: 0.039
  47. Bentley DL, Groudine M. Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas. Mol Cell Biol. 1986 Oct; 6(10):3481-9.
    View in: PubMed
    Score: 0.039
  48. Laurencikiene J, Källman AM, Fong N, Bentley DL, Ohman M. RNA editing and alternative splicing: the importance of co-transcriptional coordination. EMBO Rep. 2006 Mar; 7(3):303-7.
    View in: PubMed
    Score: 0.037
  49. Schroeder SC, Zorio DA, Schwer B, Shuman S, Bentley D. A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II. Mol Cell. 2004 Feb 13; 13(3):377-87.
    View in: PubMed
    Score: 0.032
  50. Geisberg JV, Moqtaderi Z, Fong N, Erickson B, Bentley DL, Struhl K. Nucleotide-level linkage of transcriptional elongation and polyadenylation. Elife. 2022 11 24; 11.
    View in: PubMed
    Score: 0.030
  51. Nogues G, Kadener S, Cramer P, Bentley D, Kornblihtt AR. Transcriptional activators differ in their abilities to control alternative splicing. J Biol Chem. 2002 Nov 08; 277(45):43110-4.
    View in: PubMed
    Score: 0.029
  52. Licatalosi DD, Geiger G, Minet M, Schroeder S, Cilli K, McNeil JB, Bentley DL. Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II. Mol Cell. 2002 May; 9(5):1101-11.
    View in: PubMed
    Score: 0.028
  53. Yankulov K, Todorov I, Romanowski P, Licatalosi D, Cilli K, McCracken S, Laskey R, Bentley DL. MCM proteins are associated with RNA polymerase II holoenzyme. Mol Cell Biol. 1999 Sep; 19(9):6154-63.
    View in: PubMed
    Score: 0.024
  54. Bentley D. RNA processing. A tale of two tails. Nature. 1998 Sep 03; 395(6697):21-2.
    View in: PubMed
    Score: 0.022
  55. Ho CK, Sriskanda V, McCracken S, Bentley D, Schwer B, Shuman S. The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem. 1998 Apr 17; 273(16):9577-85.
    View in: PubMed
    Score: 0.021
  56. McCracken S, Fong N, Rosonina E, Yankulov K, Brothers G, Siderovski D, Hessel A, Foster S, Shuman S, Bentley DL. 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. Genes Dev. 1997 Dec 15; 11(24):3306-18.
    View in: PubMed
    Score: 0.021
  57. Akhtar A, Faye G, Bentley DL. Distinct activated and non-activated RNA polymerase II complexes in yeast. EMBO J. 1996 Sep 02; 15(17):4654-64.
    View in: PubMed
    Score: 0.019
  58. Rodaway AR, Teahan CG, Casimir CM, Segal AW, Bentley DL. Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid. Mol Cell Biol. 1990 Oct; 10(10):5388-96.
    View in: PubMed
    Score: 0.013
  59. Muñoz MJ, Pérez Santangelo MS, Paronetto MP, de la Mata M, Pelisch F, Boireau S, Glover-Cutter K, Ben-Dov C, Blaustein M, Lozano JJ, Bird G, Bentley D, Bertrand E, Kornblihtt AR. DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell. 2009 May 15; 137(4):708-20.
    View in: PubMed
    Score: 0.012
  60. Tsuchihara K, Suzuki Y, Wakaguri H, Irie T, Tanimoto K, Hashimoto S, Matsushima K, Mizushima-Sugano J, Yamashita R, Nakai K, Bentley D, Esumi H, Sugano S. Massive transcriptional start site analysis of human genes in hypoxia cells. Nucleic Acids Res. 2009 Apr; 37(7):2249-63.
    View in: PubMed
    Score: 0.011
  61. Cesarman E, Dalla-Favera R, Bentley D, Groudine M. Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma. Science. 1987 Nov 27; 238(4831):1272-5.
    View in: PubMed
    Score: 0.010
  62. Bentley DL, Groudine M. A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells. Nature. 1986 Jun 12-18; 321(6071):702-6.
    View in: PubMed
    Score: 0.009
  63. Xie SQ, Martin S, Guillot PV, Bentley DL, Pombo A. Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain. Mol Biol Cell. 2006 Apr; 17(4):1723-33.
    View in: PubMed
    Score: 0.009
  64. Gauthier L, Dziak R, Kramer DJ, Leishman D, Song X, Ho J, Radovic M, Bentley D, Yankulov K. The role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in Saccharomyces cerevisiae. Genetics. 2002 Nov; 162(3):1117-29.
    View in: PubMed
    Score: 0.007
  65. Bentley DL, Farrell PJ, Rabbitts TH. Unrearranged immunoglobulin variable region genes have a functional promoter. Nucleic Acids Res. 1982 Mar 25; 10(6):1841-56.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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