 Connection
David Bentley to RNA Polymerase II
This is a "connection" page, showing publications David Bentley has written about RNA Polymerase II.
|
|
| |
Connection Strength |
|
 |
|
 |
| |
11.426 |
|
|
|
-
Hyder U, Bentley DL. The Promoter-Proximal Pause: A Decision Point Governing RNA Polymerase II Fate. Annu Rev Biochem. 2026 06; 95(1):221-246.
Score: 0.739
-
Erickson B, Fedoryshchak R, Fong N, Sheridan R, Larson KY, Saviola AJ, Mouilleron S, Hansen KC, Treisman R, Bentley DL. PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination. Cell Rep. 2025 May 27; 44(5):115564.
Score: 0.693
-
Bentley DL. Multiple Forms and Functions of Premature Termination by RNA Polymerase II. J Mol Biol. 2025 Jan 01; 437(1):168743.
Score: 0.661
-
Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 10 06; 82(19):3632-3645.e4.
Score: 0.582
-
Cortazar MA, Erickson B, Fong N, Pradhan SJ, Ntini E, Bentley DL. Xrn2 substrate mapping identifies torpedo loading sites and extensive premature termination of RNA pol II transcription. Genes Dev. 2022 10 01; 36(19-20):1062-1078.
Score: 0.581
-
Cortazar MA, Sheridan RM, Erickson B, Fong N, Glover-Cutter K, Brannan K, Bentley DL. Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism. Mol Cell. 2019 12 19; 76(6):896-908.e4.
Score: 0.475
-
Sheridan RM, Fong N, D'Alessandro A, Bentley DL. Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate. Mol Cell. 2019 01 03; 73(1):107-118.e4.
Score: 0.445
-
Erickson B, Sheridan RM, Cortazar M, Bentley DL. Dynamic turnover of paused Pol II complexes at human promoters. Genes Dev. 2018 09 01; 32(17-18):1215-1225.
Score: 0.437
-
Fong N, Saldi T, Sheridan RM, Cortazar MA, Bentley DL. RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction. Mol Cell. 2017 May 18; 66(4):546-557.e3.
Score: 0.400
-
Saldi T, Cortazar MA, Sheridan RM, Bentley DL. Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing. J Mol Biol. 2016 06 19; 428(12):2623-2635.
Score: 0.372
-
Fusby B, Kim S, Erickson B, Kim H, Peterson ML, Bentley DL. Coordination of RNA Polymerase II Pausing and 3' End Processing Factor Recruitment with Alternative Polyadenylation. Mol Cell Biol. 2016 01 15; 36(2):295-303.
Score: 0.360
-
Fong N, Brannan K, Erickson B, Kim H, Cortazar MA, Sheridan RM, Nguyen T, Karp S, Bentley DL. Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition. Mol Cell. 2015 Oct 15; 60(2):256-67.
Score: 0.359
-
Fong N, Kim H, Zhou Y, Ji X, Qiu J, Saldi T, Diener K, Jones K, Fu XD, Bentley DL. Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate. Genes Dev. 2014 Dec 01; 28(23):2663-76.
Score: 0.338
-
Brannan K, Kim H, Erickson B, Glover-Cutter K, Kim S, Fong N, Kiemele L, Hansen K, Davis R, Lykke-Andersen J, Bentley DL. mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription. Mol Cell. 2012 May 11; 46(3):311-24.
Score: 0.281
-
Perales R, Zhang L, Bentley D. Histone occupancy in vivo at the 601 nucleosome binding element is determined by transcriptional history. Mol Cell Biol. 2011 Aug; 31(16):3485-96.
Score: 0.266
-
Kim H, Erickson B, Luo W, Seward D, Graber JH, Pollock DD, Megee PC, Bentley DL. Gene-specific RNA polymerase II phosphorylation and the CTD code. Nat Struct Mol Biol. 2010 Oct; 17(10):1279-86.
Score: 0.252
-
Fong N, Ohman M, Bentley DL. Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing. Nat Struct Mol Biol. 2009 Sep; 16(9):916-22.
Score: 0.234
-
Glover-Cutter K, Larochelle S, Erickson B, Zhang C, Shokat K, Fisher RP, Bentley DL. TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II. Mol Cell Biol. 2009 Oct; 29(20):5455-64.
Score: 0.234
-
Glover-Cutter K, Kim S, Espinosa J, Bentley DL. RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes. Nat Struct Mol Biol. 2008 Jan; 15(1):71-8.
Score: 0.209
-
Shenasa H, Fong N, Erickson B, Iosub IA, Ule J, Bentley DL. CAR-SPLASH identifies nascent pre-mRNA structures implicated in kinetic coupling and alternative splicing. Proc Natl Acad Sci U S A. 2025 Oct 07; 122(40):e2504034122.
Score: 0.179
-
Luo W, Bentley D. A ribonucleolytic rat torpedoes RNA polymerase II. Cell. 2004 Dec 29; 119(7):911-4.
Score: 0.170
-
Blears D, Lou J, Fong N, Mitter R, Sheridan RM, He D, Dirac-Svejstrup AB, Bentley D, Svejstrup JQ. Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint. Mol Cell. 2024 Dec 19; 84(24):4790-4807.e11.
Score: 0.168
-
Bird G, Zorio DA, Bentley DL. RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formation. Mol Cell Biol. 2004 Oct; 24(20):8963-9.
Score: 0.167
-
Schroeder SC, Zorio DA, Schwer B, Shuman S, Bentley D. A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II. Mol Cell. 2004 Feb 13; 13(3):377-87.
Score: 0.160
-
Fong N, Bird G, Vigneron M, Bentley DL. A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing. EMBO J. 2003 Aug 15; 22(16):4274-82.
Score: 0.154
-
Licatalosi DD, Geiger G, Minet M, Schroeder S, Cilli K, McNeil JB, Bentley DL. Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II. Mol Cell. 2002 May; 9(5):1101-11.
Score: 0.141
-
Fong N, Bentley DL. Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD. Genes Dev. 2001 Jul 15; 15(14):1783-95.
Score: 0.134
-
Saldi T, Riemondy K, Erickson B, Bentley DL. Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing. Mol Cell. 2021 04 15; 81(8):1789-1801.e5.
Score: 0.130
-
Schroeder SC, Schwer B, Shuman S, Bentley D. Dynamic association of capping enzymes with transcribing RNA polymerase II. Genes Dev. 2000 Oct 01; 14(19):2435-40.
Score: 0.126
-
Bentley D. Coupling RNA polymerase II transcription with pre-mRNA processing. Curr Opin Cell Biol. 1999 Jun; 11(3):347-51.
Score: 0.115
-
Bentley D. RNA processing. A tale of two tails. Nature. 1998 Sep 03; 395(6697):21-2.
Score: 0.110
-
McNeil JB, Agah H, Bentley D. Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev. 1998 Aug 15; 12(16):2510-21.
Score: 0.109
-
McCracken S, Rosonina E, Fong N, Sikes M, Beyer A, O'Hare K, Shuman S, Bentley D. Role of RNA polymerase II carboxy-terminal domain in coordinating transcription with RNA processing. Cold Spring Harb Symp Quant Biol. 1998; 63:301-9.
Score: 0.105
-
McCracken S, Fong N, Yankulov K, Ballantyne S, Pan G, Greenblatt J, Patterson SD, Wickens M, Bentley DL. The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature. 1997 Jan 23; 385(6614):357-61.
Score: 0.098
-
Akhtar A, Faye G, Bentley DL. Distinct activated and non-activated RNA polymerase II complexes in yeast. EMBO J. 1996 Sep 02; 15(17):4654-64.
Score: 0.095
-
Yankulov KY, Pandes M, McCracken S, Bouchard D, Bentley DL. TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes. Mol Cell Biol. 1996 Jul; 16(7):3291-9.
Score: 0.094
-
Blau J, Xiao H, McCracken S, O'Hare P, Greenblatt J, Bentley D. Three functional classes of transcriptional activation domain. Mol Cell Biol. 1996 May; 16(5):2044-55.
Score: 0.093
-
Yankulov K, Yamashita K, Roy R, Egly JM, Bentley DL. The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. J Biol Chem. 1995 Oct 13; 270(41):23922-5.
Score: 0.090
-
Bentley DL. Regulation of transcriptional elongation by RNA polymerase II. Curr Opin Genet Dev. 1995 Apr; 5(2):210-6.
Score: 0.086
-
Yankulov K, Blau J, Purton T, Roberts S, Bentley DL. Transcriptional elongation by RNA polymerase II is stimulated by transactivators. Cell. 1994 Jun 03; 77(5):749-59.
Score: 0.082
-
Bentley DL. Coupling mRNA processing with transcription in time and space. Nat Rev Genet. 2014 03; 15(3):163-75.
Score: 0.080
-
Larochelle S, Amat R, Glover-Cutter K, Sansó M, Zhang C, Allen JJ, Shokat KM, Bentley DL, Fisher RP. Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II. Nat Struct Mol Biol. 2012 Nov; 19(11):1108-15.
Score: 0.073
-
Roberts S, Purton T, Bentley DL. A protein-binding site in the c-myc promoter functions as a terminator of RNA polymerase II transcription. Genes Dev. 1992 Aug; 6(8):1562-74.
Score: 0.072
-
Perales R, Bentley D. "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. Mol Cell. 2009 Oct 23; 36(2):178-91.
Score: 0.059
-
Muñoz MJ, Pérez Santangelo MS, Paronetto MP, de la Mata M, Pelisch F, Boireau S, Glover-Cutter K, Ben-Dov C, Blaustein M, Lozano JJ, Bird G, Bentley D, Bertrand E, Kornblihtt AR. DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. Cell. 2009 May 15; 137(4):708-20.
Score: 0.057
-
Bentley DL, Groudine M. Sequence requirements for premature termination of transcription in the human c-myc gene. Cell. 1988 Apr 22; 53(2):245-56.
Score: 0.053
-
Ryman K, Fong N, Bratt E, Bentley DL, Ohman M. The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript. RNA. 2007 Jul; 13(7):1071-8.
Score: 0.050
-
Xie SQ, Martin S, Guillot PV, Bentley DL, Pombo A. Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain. Mol Biol Cell. 2006 Apr; 17(4):1723-33.
Score: 0.046
-
Bird G, Fong N, Gatlin JC, Farabaugh S, Bentley DL. Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing. Mol Cell. 2005 Dec 09; 20(5):747-58.
Score: 0.045
-
Bentley DL. Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. Curr Opin Cell Biol. 2005 Jun; 17(3):251-6.
Score: 0.044
-
Zorio DA, Bentley DL. The link between mRNA processing and transcription: communication works both ways. Exp Cell Res. 2004 May 15; 296(1):91-7.
Score: 0.041
-
de la Mata M, Alonso CR, Kadener S, Fededa JP, Blaustein M, Pelisch F, Cramer P, Bentley D, Kornblihtt AR. A slow RNA polymerase II affects alternative splicing in vivo. Mol Cell. 2003 Aug; 12(2):525-32.
Score: 0.038
-
Geisberg JV, Moqtaderi Z, Fong N, Erickson B, Bentley DL, Struhl K. Nucleotide-level linkage of transcriptional elongation and polyadenylation. Elife. 2022 11 24; 11.
Score: 0.037
-
Gauthier L, Dziak R, Kramer DJ, Leishman D, Song X, Ho J, Radovic M, Bentley D, Yankulov K. The role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in Saccharomyces cerevisiae. Genetics. 2002 Nov; 162(3):1117-29.
Score: 0.037
-
Bentley D. The mRNA assembly line: transcription and processing machines in the same factory. Curr Opin Cell Biol. 2002 Jun; 14(3):336-42.
Score: 0.035
-
Zorio DA, Bentley DL. Transcription elongation: the 'Foggy' is liftingellipsis. Curr Biol. 2001 Feb 20; 11(4):R144-6.
Score: 0.032
-
Ho CK, Sriskanda V, McCracken S, Bentley D, Schwer B, Shuman S. The guanylyltransferase domain of mammalian mRNA capping enzyme binds to the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem. 1998 Apr 17; 273(16):9577-85.
Score: 0.027
-
Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. Cell Rep. 2017 08 01; 20(5):1173-1186.
Score: 0.025
-
Roberts S, Bentley DL. Distinct modes of transcription read through or terminate at the c-myc attenuator. EMBO J. 1992 Mar; 11(3):1085-93.
Score: 0.017
-
Bentley DL, Brown WL, Groudine M. Accurate, TATA box-dependent polymerase III transcription from promoters of the c-myc gene in injected Xenopus oocytes. Genes Dev. 1989 Aug; 3(8):1179-89.
Score: 0.015
-
Laurencikiene J, Källman AM, Fong N, Bentley DL, Ohman M. RNA editing and alternative splicing: the importance of co-transcriptional coordination. EMBO Rep. 2006 Mar; 7(3):303-7.
Score: 0.011
-
Nogues G, Kadener S, Cramer P, Bentley D, Kornblihtt AR. Transcriptional activators differ in their abilities to control alternative splicing. J Biol Chem. 2002 Nov 08; 277(45):43110-4.
Score: 0.009
|
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
|