EdwardChanEdward David Chan39.74515960000000-104.840628000000001179Chan, EdwardDavid303/315-7767Principal Investigatorprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 811033Authorship 81867Authorship 890054Authorship 894471Authorship 8955619Authorship 898087Authorship 910791Authorship 1210811Authorship 1204713Authorship 1213513Authorship 121856315230087Kalman D, Lee A, Chan E, Miller DR, Spiro A, Ren XS, Kazis LEThe American journal of drug and alcohol abuseKalman D, Lee A, Chan E, Miller DR, Spiro A, Ren XS, Kazis LE. Alcohol dependence, other psychiatric disorders, and health-related quality of life: a replication study in a large random sample of enrollees in the Veterans Health Administration. Am J Drug Alcohol Abuse. 2004 May; 30(2):473-87.Am J Drug Alcohol Abuse2004-05-01T00:00:002004Alcohol dependence, other psychiatric disorders, and health-related quality of life: a replication study in a large random sample of enrollees in the Veterans Health Administration.25581353Honda JR, Wallace RJ, Chan EDRespirology (Carlton, Vic.)Honda JR, Wallace RJ, Chan ED. First you have to row a little boat. Respirology. 2015 Feb; 20(2):181-2.Respirology2015-01-07T00:00:002015First you have to row a little boat.25644904Honda JR, Bernhard JN, Chan EDChestHonda JR, Bernhard JN, Chan ED. Natural disasters and nontuberculous mycobacteria: a recipe for increased disease? Chest. 2015 Feb; 147(2):304-308.Chest2015-02-01T00:00:002015Natural disasters and nontuberculous mycobacteria: a recipe for increased disease?Authorship 122538223200552Wang CH, Chan ED, Perng CL, Chian CF, Chen CW, Perng WC, Su WLJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhiWang CH, Chan ED, Perng CL, Chian CF, Chen CW, Perng WC, Su WL. Intravenous immunoglobulin replacement therapy to prevent pulmonary infection in a patient with Good's syndrome. J Microbiol Immunol Infect. 2015 Apr; 48(2):229-32.J Microbiol Immunol Infect2012-11-29T00:00:002012Intravenous immunoglobulin replacement therapy to prevent pulmonary infection in a patient with Good's syndrome.Authorship 927461Authorship 123083325676515Honda JR, Knight V, Chan EDClinics in chest medicineHonda JR, Knight V, Chan ED. Pathogenesis and risk factors for nontuberculous mycobacterial lung disease. Clin Chest Med. 2015 Mar; 36(1):1-11.Clin Chest Med2014-11-06T00:00:002014Pathogenesis and risk factors for nontuberculous mycobacterial lung disease.Authorship 1235251Authorship 1235391025677598Chan E, Anderson CS, Wang X, Arima H, Saxena A, Moullaali TJ, Heeley E, Delcourt C, Wu G, Wang J, Chen G, Lavados PM, Stapf C, Robinson T, Chalmers J, Huang YStrokeChan E, Anderson CS, Wang X, Arima H, Saxena A, Moullaali TJ, Heeley E, Delcourt C, Wu G, Wang J, Chen G, Lavados PM, Stapf C, Robinson T, Chalmers J, Huang Y. Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke. 2015 Mar; 46(3):653-8.Stroke2015-02-12T00:00:002015Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results.25808744Bishwakarma R, Kinney WH, Honda JR, Mya J, Strand MJ, Gangavelli A, Bai X, Ordway DJ, Iseman MD, Chan EDRespirology (Carlton, Vic.)Bishwakarma R, Kinney WH, Honda JR, Mya J, Strand MJ, Gangavelli A, Bai X, Ordway DJ, Iseman MD, Chan ED. Epidemiologic link between tuberculosis and cigarette/biomass smoke exposure: Limitations despite the vast literature. Respirology. 2015 May; 20(4):556-68.Respirology2015-03-25T00:00:002015Epidemiologic link between tuberculosis and cigarette/biomass smoke exposure: Limitations despite the vast literature.Authorship 12396321Authorship 1240811125820174Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan EDProceedings of the National Academy of Sciences of the United States of AmericaBai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan ED. Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5111-6.Proc Natl Acad Sci U S A2015-03-27T00:00:002015Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.25887904Bai X, Kinney WH, Su WL, Bai A, Ovrutsky AR, Honda JR, Netea MG, Henao-Tamayo M, Ordway DJ, Dinarello CA, Chan EDBMC microbiologyBai X, Kinney WH, Su WL, Bai A, Ovrutsky AR, Honda JR, Netea MG, Henao-Tamayo M, Ordway DJ, Dinarello CA, Chan ED. Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells. BMC Microbiol. 2015 Feb 21; 15:39.BMC Microbiol2015-02-21T00:00:002015Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.Authorship 125284825993058Honda JR, Hess T, Malcolm KC, Ovrutsky AR, Bai X, Irani VR, Dobos KM, Chan ED, Flores SCPloS oneHonda JR, Hess T, Malcolm KC, Ovrutsky AR, Bai X, Irani VR, Dobos KM, Chan ED, Flores SC. Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. PLoS One. 2015; 10(5):e0126994.PLoS One2015-05-18T00:00:002015Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids.Authorship 952701Authorship 131816326144292Bai X, Dinarello CA, Chan EDCytokineBai X, Dinarello CA, Chan ED. The role of interleukin-32 against tuberculosis. Cytokine. 2015 Dec; 76(2):585-587.Cytokine2015-07-03T00:00:002015The role of interleukin-32 against tuberculosis.27012592Bai X, Oberley-Deegan RE, Bai A, Ovrutsky AR, Kinney WH, Weaver M, Zhang G, Honda JR, Chan EDRespirology (Carlton, Vic.)Bai X, Oberley-Deegan RE, Bai A, Ovrutsky AR, Kinney WH, Weaver M, Zhang G, Honda JR, Chan ED. Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection. Respirology. 2016 Jul; 21(5):951-7.Respirology2016-03-24T00:00:002016Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection.Authorship 1388364Authorship 1390701526757804Fox GJ, Mitnick CD, Benedetti A, Chan ED, Becerra M, Chiang CY, Keshavjee S, Koh WJ, Shiraishi Y, Viiklepp P, Yim JJ, Pasvol G, Robert J, Shim TS, Shin SS, Menzies D, Ahuja S, Ashkin D, Avenda?o M, Banerjee R, Bauer M, Burgos M, Centis R, Cobelens F, Cox H, D'Ambrosio L, de Lange WCM, DeRiemer K, Enarson D, Falzon D, Flanagan K, Flood J, Gandhi N, Garcia-Garcia L, Granich RM, Hollm-Delgado MG, Holtz TH, Hopewell P, Iseman M, Jarlsberg LG, Kim HR, Lancaster J, Lange C, Leimane V, Leung CC, Li J, Menzies D, Migliori GB, Narita M, Nathanson E, Odendaal R, O'Riordan P, Pai M, Palmero D, Park SK, Pena J, P?rez-Guzm?n C, Ponce-de-Leon A, Quelapio MID, Quy HT, Riekstina V, Royce S, Salim M, Schaaf HS, Seung KJ, Shah L, Shean K, Sifuentes-Osornio J, Sotgiu G, Strand MJ, Sung SW, Tabarsi P, Tupasi TE, Vargas MH, van Altena R, van der Walt M, van der Werf TS, Westenhouse J, Yew WWClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaFox GJ, Mitnick CD, Benedetti A, Chan ED, Becerra M, Chiang CY, Keshavjee S, Koh WJ, Shiraishi Y, Viiklepp P, Yim JJ, Pasvol G, Robert J, Shim TS, Shin SS, Menzies D, Ahuja S, Ashkin D, Avenda?o M, Banerjee R, Bauer M, Burgos M, Centis R, Cobelens F, Cox H, D'Ambrosio L, de Lange WCM, DeRiemer K, Enarson D, Falzon D, Flanagan K, Flood J, Gandhi N, Garcia-Garcia L, Granich RM, Hollm-Delgado MG, Holtz TH, Hopewell P, Iseman M, Jarlsberg LG, Kim HR, Lancaster J, Lange C, Leimane V, Leung CC, Li J, Menzies D, Migliori GB, Narita M, Nathanson E, Odendaal R, O'Riordan P, Pai M, Palmero D, Park SK, Pena J, P?rez-Guzm?n C, Ponce-de-Leon A, Quelapio MID, Quy HT, Riekstina V, Royce S, Salim M, Schaaf HS, Seung KJ, Shah L, Shean K, Sifuentes-Osornio J, Sotgiu G, Strand MJ, Sung SW, Tabarsi P, Tupasi TE, Vargas MH, van Altena R, van der Walt M, van der Werf TS, Westenhouse J, Yew WW. Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis. Clin Infect Dis. 2016 Apr 01; 62(7):887-895.Clin Infect Dis2016-01-12T00:00:002016Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis.26764424Abe J, Alop-Mabuti A, Burger P, Button J, Ellsberry M, Hitzeman J, Morgenstern D, Nunies K, Strother M, Darling-Munson J, Chan YL, Cassady R, Vasconcellos SM, Iseman MD, Chan ED, Honda JRFEMS microbiology lettersAbe J, Alop-Mabuti A, Burger P, Button J, Ellsberry M, Hitzeman J, Morgenstern D, Nunies K, Strother M, Darling-Munson J, Chan YL, Cassady R, Vasconcellos SM, Iseman MD, Chan ED, Honda JR. Comparing the temporal colonization and microbial diversity of showerhead biofilms in Hawai'i and Colorado. FEMS Microbiol Lett. 2016 Feb; 363(4).FEMS Microbiol Lett2016-01-12T00:00:002016Comparing the temporal colonization and microbial diversity of showerhead biofilms in Hawai'i and Colorado.Authorship 1428019Authorship 142921427287596Foster CL, Badlam J, De Groote MA, Chan EDChestFoster CL, Badlam J, De Groote MA, Chan ED. A 65-Year-Old Groundskeeper With High Fever, Pulmonary Nodules, and Thoracic Lymphadenopathy. Chest. 2016 Jun; 149(6):e191-4.Chest2016-06-01T00:00:002016A 65-Year-Old Groundskeeper With High Fever, Pulmonary Nodules, and Thoracic Lymphadenopathy.DanielWinnicaDaniel Winnica39.74515960000000-104.8406280000000011793Winnica, DanielAsst Professor-ResearchAuthorship 148927927534685Walter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GKThe Journal of infectious diseasesWalter ND, de Jong BC, Garcia BJ, Dolganov GM, Worodria W, Byanyima P, Musisi E, Huang L, Chan ED, Van TT, Antonio M, Ayorinde A, Kato-Maeda M, Nahid P, Leung AM, Yen A, Fingerlin TE, Kechris K, Strong M, Voskuil MI, Davis JL, Schoolnik GK. Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients. J Infect Dis. 2016 10 15; 214(8):1205-11.J Infect Dis2016-08-17T00:00:002016Adaptation of Mycobacterium tuberculosis to Impaired Host Immunity in HIV-Infected Patients.11777978Tse HM, Josephy SI, Chan ED, Fouts D, Cooper AMJournal of immunology (Baltimore, Md. : 1950)Tse HM, Josephy SI, Chan ED, Fouts D, Cooper AM. Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages. J Immunol. 2002 Jan 15; 168(2):825-33.J Immunol2002-01-15T00:00:002002Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages.Authorship 1520331127780201Honda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong MPLoS neglected tropical diseasesHonda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong M. Environmental Nontuberculous Mycobacteria in the Hawaiian Islands. PLoS Negl Trop Dis. 2016 Oct; 10(10):e0005068.PLoS Negl Trop Dis2016-10-25T00:00:002016Environmental Nontuberculous Mycobacteria in the Hawaiian Islands.Authorship 153307627881537Hasan NA, Honda JR, Davidson RM, Epperson LE, Bankowski MJ, Chan ED, Strong MGenome announcementsHasan NA, Honda JR, Davidson RM, Epperson LE, Bankowski MJ, Chan ED, Strong M. Complete Genome Sequence of Mycobacterium chimaera Strain AH16. Genome Announc. 2016 Nov 23; 4(6).Genome Announc2016-11-23T00:00:002016Complete Genome Sequence of Mycobacterium chimaera Strain AH16.12119230Choi HS, Rai PR, Chu HW, Cool C, Chan EDAmerican journal of respiratory and critical care medicineChoi HS, Rai PR, Chu HW, Cool C, Chan ED. Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med. 2002 Jul 15; 166(2):178-86.Am J Respir Crit Care Med2002-07-15T00:00:002002Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis.Authorship 1536281127911953Honda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong MPLoS neglected tropical diseasesHonda JR, Hasan NA, Davidson RM, Williams MD, Epperson LE, Reynolds PR, Smith T, Iakhiaeva E, Bankowski MJ, Wallace RJ, Chan ED, Falkinham JO, Strong M. Correction: Environmental Nontuberculous Mycobacteria in the Hawaiian Islands. PLoS Negl Trop Dis. 2016 Dec; 10(12):e0005200.PLoS Negl Trop Dis2016-12-02T00:00:002016Correction: Environmental Nontuberculous Mycobacteria in the Hawaiian Islands.12595462Morris KR, Lutz RD, Choi HS, Kamitani T, Chmura K, Chan EDInfection and immunityMorris KR, Lutz RD, Choi HS, Kamitani T, Chmura K, Chan ED. Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide. Infect Immun. 2003 Mar; 71(3):1442-52.Infect Immun2003-03-01T00:00:002003Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide.Authorship 1563271328100548Becker KL, Arts P, Jaeger M, Plantinga TS, Gilissen C, van Laarhoven A, van Ingen J, Veltman JA, Joosten LA, Hoischen A, Netea MG, Iseman MD, Chan ED, van de Veerdonk FLThe European respiratory journalBecker KL, Arts P, Jaeger M, Plantinga TS, Gilissen C, van Laarhoven A, van Ingen J, Veltman JA, Joosten LA, Hoischen A, Netea MG, Iseman MD, Chan ED, van de Veerdonk FL. MST1R mutation as a genetic cause of Lady Windermere syndrome. Eur Respir J. 2017 01; 49(1).Eur Respir J2017-01-18T00:00:002017MST1R mutation as a genetic cause of Lady Windermere syndrome.12849985Bai X, Chan ED, Xu XBiochemical and biophysical research communicationsBai X, Chan ED, Xu X. The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis. Biochem Biophys Res Commun. 2003 Jul 18; 307(1):86-91.Biochem Biophys Res Commun2003-07-18T00:00:002003The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis.Authorship 1567541027920257Farabaugh KT, Majumder M, Guan BJ, Jobava R, Wu J, Krokowski D, Gao XH, Schuster A, Longworth M, Chan ED, Bianchi M, Dey M, Koromilas AE, Ramakrishnan P, Hatzoglou MMolecular and cellular biologyFarabaugh KT, Majumder M, Guan BJ, Jobava R, Wu J, Krokowski D, Gao XH, Schuster A, Longworth M, Chan ED, Bianchi M, Dey M, Koromilas AE, Ramakrishnan P, Hatzoglou M. Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress. Mol Cell Biol. 2017 02 15; 37(4).Mol Cell Biol2017-02-01T00:00:002017Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress.5Other Faculty1Professor14742308Bowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MWAmerican journal of physiology. Lung cellular and molecular physiologyBowler RP, Duda B, Chan ED, Enghild JJ, Ware LB, Matthay MA, Duncan MW. Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1095-104.Am J Physiol Lung Cell Mol Physiol2004-01-23T00:00:002004Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury.3Asst Professor2Assoc Professor4Instructor7Fellow or Post DocAuthorship 157655828183502Williams JG, Phan H, Winston HR, Fugit RV, Graney B, Jamroz B, English B, Chan EDChestWilliams JG, Phan H, Winston HR, Fugit RV, Graney B, Jamroz B, English B, Chan ED. A 27-Year-Old Man With Acute Severe Low Back Pain and Bilateral Leg Swelling That Prompted Renting a Wheelchair for Mobility. Chest. 2017 Feb; 151(2):e35-e39.Chest2017-02-01T00:00:002017A 27-Year-Old Man With Acute Severe Low Back Pain and Bilateral Leg Swelling That Prompted Renting a Wheelchair for Mobility.YanHuYan Hu39.74515960000000-104.8406280000000012575Hu, YanPost-Doctoral Fellow12700 East 19th Avenue2RC2Research 212700 East 19th AvenueAurora80045-2560COAuthorship 162040728398760Bai X, Stitzel JA, Bai A, Zambrano CA, Phillips M, Marrack P, Chan EDAmerican journal of respiratory cell and molecular biologyBai X, Stitzel JA, Bai A, Zambrano CA, Phillips M, Marrack P, Chan ED. Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis. Am J Respir Cell Mol Biol. 2017 09; 57(3):324-333.Am J Respir Cell Mol Biol2017-09-01T00:00:002017Nicotine Impairs Macrophage Control of Mycobacterium tuberculosis.2007-11-30NIHCHAN, EDWARD D2001-07-15Host defense functions of M. tuberculosis lipoglycanR01HL0661122001-12-31NIHCHAN, EDWARD D1997-01-01REGULATION OF INSULIN LIKE GROWTH FACTOR IK08HL0036252019-05-31NIHCHAN, EDWARD D2016-06-14The role of T regulatory cells in cigarette smoke-induced susceptibility to tuberculosisR21AI1216052015-09-30NIHCHAN, EDWARD D2011-10-01Mechanistic study of the host defense functions of IL-32 in tuberculosisI01BX001028Principal InvestigatorPrincipal InvestigatorPrincipal InvestigatorPrincipal Investigator16141243Wieland CW, Florquin S, Chan ED, Leemans JC, Weijer S, Verbon A, Fantuzzi G, van der Poll TInternational immunologyWieland CW, Florquin S, Chan ED, Leemans JC, Weijer S, Verbon A, Fantuzzi G, van der Poll T. Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol. 2005 Nov; 17(11):1399-408.Int Immunol2005-09-01T00:00:002005Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice.16903774Netea MG, Azam T, Lewis EC, Joosten LA, Wang M, Langenberg D, Meng X, Chan ED, Yoon DY, Ottenhoff T, Kim SH, Dinarello CAPLoS medicineNetea MG, Azam T, Lewis EC, Joosten LA, Wang M, Langenberg D, Meng X, Chan ED, Yoon DY, Ottenhoff T, Kim SH, Dinarello CA. Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism. PLoS Med. 2006 Aug; 3(8):e277.PLoS Med2006-08-01T00:00:002006Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.16647268Chan MM, Chmura K, Chan EDCytokineChan MM, Chmura K, Chan ED. Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene. Cytokine. 2006 Mar 21; 33(6):309-16.Cytokine2006-03-21T00:00:002006Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene.16723291Sullivan A, Chmura K, Cool CD, Keith R, Schwartz GG, Chan EDEuropean journal of medical researchSullivan A, Chmura K, Cool CD, Keith R, Schwartz GG, Chan ED. Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling. Eur J Med Res. 2006 May 05; 11(5):187-93.Eur J Med Res2006-05-05T00:00:002006Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling.17035464Gray K, Chan ED, Alvarado JChestGray K, Chan ED, Alvarado J. A 48-year-old woman with multiple pulmonary nodules and a right ventricular mass. Chest. 2006 Oct; 130(4):1248-51.Chest2006-10-01T00:00:002006A 48-year-old woman with multiple pulmonary nodules and a right ventricular mass.17245714Liu L, Bastien N, Sidaway F, Chan E, Li YJournal of medical virologyLiu L, Bastien N, Sidaway F, Chan E, Li Y. Seroprevalence of human metapneumovirus (hMPV) in the Canadian province of Saskatchewan analyzed by a recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay. J Med Virol. 2007 Mar; 79(3):308-13.J Med Virol2007-03-01T00:00:002007Seroprevalence of human metapneumovirus (hMPV) in the Canadian province of Saskatchewan analyzed by a recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay.Authorship 162615528428297Zhao X, Epperson LE, Hasan NA, Honda JR, Chan ED, Strong M, Walter ND, Davidson RMGenome announcementsZhao X, Epperson LE, Hasan NA, Honda JR, Chan ED, Strong M, Walter ND, Davidson RM. Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample. Genome Announc. 2017 Apr 20; 5(16).Genome Announc2017-04-20T00:00:002017Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample.17654345Chan ED, Kaminska AM, Gill W, Chmura K, Feldman NE, Bai X, Floyd CM, Fulton KE, Huitt GA, Strand MJ, Iseman MD, Shapiro LScandinavian journal of infectious diseasesChan ED, Kaminska AM, Gill W, Chmura K, Feldman NE, Bai X, Floyd CM, Fulton KE, Huitt GA, Strand MJ, Iseman MD, Shapiro L. Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages. Scand J Infect Dis. 2007; 39(8):690-6.Scand J Infect Dis2007-01-01T00:00:002007Alpha-1-antitrypsin (AAT) anomalies are associated with lung disease due to rapidly growing mycobacteria and AAT inhibits Mycobacterium abscessus infection of macrophages.28458623Lee S, Choi DK, Kwak A, Kim S, Nguyen TT, Gil G, Kim E, Yoo KH, Kim IA, Lee Y, Jhun H, Chan ED, Bai X, Kim H, Kim YS, Kim SImmune networkLee S, Choi DK, Kwak A, Kim S, Nguyen TT, Gil G, Kim E, Yoo KH, Kim IA, Lee Y, Jhun H, Chan ED, Bai X, Kim H, Kim YS, Kim S. IL-32-induced Inflammatory Cytokines Are Selectively Suppressed by a1-antitrypsin in Mouse Bone Marrow Cells. Immune Netw. 2017 Apr; 17(2):116-120.Immune Netw2017-04-20T00:00:002017IL-32-induced Inflammatory Cytokines Are Selectively Suppressed by a1-antitrypsin in Mouse Bone Marrow Cells.18321909Sergew A, Merrick D, Chan EDChestSergew A, Merrick D, Chan ED. A 64-year-old man with joint swelling and an abnormal chest radiograph. Chest. 2008 Mar; 133(3):805-8.Chest2008-03-01T00:00:002008A 64-year-old man with joint swelling and an abnormal chest radiograph.18390654Miller RM, Tomaras AP, Barker AP, Voelker DR, Chan ED, Vasil AI, Vasil MLJournal of bacteriologyMiller RM, Tomaras AP, Barker AP, Voelker DR, Chan ED, Vasil AI, Vasil ML. Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements. J Bacteriol. 2008 Jun; 190(11):4038-49.J Bacteriol2008-04-04T00:00:002008Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements.18687654Chan ED, Strand MJ, Iseman MDThe New England journal of medicineChan ED, Strand MJ, Iseman MD. Treatment outcomes in extensively resistant tuberculosis. N Engl J Med. 2008 Aug 07; 359(6):657-9.N Engl J Med2008-08-07T00:00:002008Treatment outcomes in extensively resistant tuberculosis.18978526Chan ED, Iseman MDCurrent opinion in infectious diseasesChan ED, Iseman MD. Multidrug-resistant and extensively drug-resistant tuberculosis: a review. Curr Opin Infect Dis. 2008 Dec; 21(6):587-95.Curr Opin Infect Dis2008-12-01T00:00:002008Multidrug-resistant and extensively drug-resistant tuberculosis: a review.19197072Pott GB, Chan ED, Dinarello CA, Shapiro LJournal of leukocyte biologyPott GB, Chan ED, Dinarello CA, Shapiro L. Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol. 2009 May; 85(5):886-95.J Leukoc Biol2009-02-05T00:00:002009Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood.19273531Bai X, Silvius D, Chan ED, Escalier D, Xu SXNucleic acids researchBai X, Silvius D, Chan ED, Escalier D, Xu SX. Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2. Nucleic Acids Res. 2009 May; 37(8):2699-711.Nucleic Acids Res2009-03-09T00:00:002009Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2.Authorship 166612728754702Malcolm KC, Caceres SM, Honda JR, Davidson RM, Epperson LE, Strong M, Chan ED, Nick JAApplied and environmental microbiologyMalcolm KC, Caceres SM, Honda JR, Davidson RM, Epperson LE, Strong M, Chan ED, Nick JA. Mycobacterium abscessus Displays Fitness for Fomite Transmission. Appl Environ Microbiol. 2017 10 01; 83(19).Appl Environ Microbiol2017-09-15T00:00:002017Mycobacterium abscessus Displays Fitness for Fomite Transmission.19880327Hong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim SCytokineHong J, Bae S, Kang Y, Yoon D, Bai X, Chan ED, Azam T, Dinarello CA, Lee S, Her E, Rho G, Kim S. Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine. 2010 Feb; 49(2):171-6.Cytokine2009-10-31T00:00:002009Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta.20189150Chan ED, Iseman MDGender medicineChan ED, Iseman MD. Slender, older women appear to be more susceptible to nontuberculous mycobacterial lung disease. Gend Med. 2010 Feb; 7(1):5-18.Gend Med2010-02-01T00:00:002010Slender, older women appear to be more susceptible to nontuberculous mycobacterial lung disease.Authorship 1677707Authorship 1678681228529461Philley JV, DeGroote MA, Honda JR, Chan MM, Kasperbauer S, Walter ND, Chan EDCurrent treatment options in infectious diseasesPhilley JV, DeGroote MA, Honda JR, Chan MM, Kasperbauer S, Walter ND, Chan ED. Treatment of Non-Tuberculous Mycobacterial Lung Disease. Curr Treat Options Infect Dis. 2016 Dec; 8(4):275-296.Curr Treat Options Infect Dis2016-10-11T00:00:002016Treatment of Non-Tuberculous Mycobacterial Lung Disease.20807564Oberley-Deegan RE, Rebits BW, Weaver MR, Tollefson AK, Bai X, McGibney M, Ovrutsky AR, Chan ED, Crapo JDFree radical biology & medicineOberley-Deegan RE, Rebits BW, Weaver MR, Tollefson AK, Bai X, McGibney M, Ovrutsky AR, Chan ED, Crapo JD. An oxidative environment promotes growth of Mycobacterium abscessus. Free Radic Biol Med. 2010 Dec 01; 49(11):1666-73.Free Radic Biol Med2010-08-31T00:00:002010An oxidative environment promotes growth of Mycobacterium abscessus.21177982Walter ND, Rice PL, Redente EF, Kauvar EF, Lemond L, Aly T, Wanebo K, Chan EDAmerican journal of respiratory cell and molecular biologyWalter ND, Rice PL, Redente EF, Kauvar EF, Lemond L, Aly T, Wanebo K, Chan ED. Wound healing after trauma may predispose to lung cancer metastasis: review of potential mechanisms. Am J Respir Cell Mol Biol. 2011 May; 44(5):591-6.Am J Respir Cell Mol Biol2010-12-22T00:00:002010Wound healing after trauma may predispose to lung cancer metastasis: review of potential mechanisms.21357942Shang S, Ordway D, Henao-Tamayo M, Bai X, Oberley-Deegan R, Shanley C, Orme IM, Case S, Minor M, Ackart D, Hascall-Dove L, Ovrutsky AR, Kandasamy P, Voelker DR, Lambert C, Freed BM, Iseman MD, Basaraba RJ, Chan EDThe Journal of infectious diseasesShang S, Ordway D, Henao-Tamayo M, Bai X, Oberley-Deegan R, Shanley C, Orme IM, Case S, Minor M, Ackart D, Hascall-Dove L, Ovrutsky AR, Kandasamy P, Voelker DR, Lambert C, Freed BM, Iseman MD, Basaraba RJ, Chan ED. Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models. J Infect Dis. 2011 May 01; 203(9):1240-8.J Infect Dis2011-02-28T00:00:002011Cigarette smoke increases susceptibility to tuberculosis--evidence from in vivo and in vitro models.21732087Coffey D, Fain B, Thompson C, Chan ED, Nawaz SAnnals of hematologyCoffey D, Fain B, Thompson C, Chan ED, Nawaz S. Liver failure as the only clinical manifestation of multiple myeloma. Ann Hematol. 2012 Apr; 91(4):625-7.Ann Hematol2011-07-06T00:00:002011Liver failure as the only clinical manifestation of multiple myeloma.21737349Shang S, Harton M, Tamayo MH, Shanley C, Palanisamy GS, Caraway M, Chan ED, Basaraba RJ, Orme IM, Ordway DJTuberculosis (Edinburgh, Scotland)Shang S, Harton M, Tamayo MH, Shanley C, Palanisamy GS, Caraway M, Chan ED, Basaraba RJ, Orme IM, Ordway DJ. Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis. Tuberculosis (Edinb). 2011 Sep; 91(5):378-85.Tuberculosis (Edinb)2011-07-06T00:00:002011Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis.21965019Ovrutsky AR, Kartalija M, Bai X, Chan EDAmerican journal of respiratory and critical care medicineOvrutsky AR, Kartalija M, Bai X, Chan ED. A trojan horse strategy to deliver amikacin to mycobacterial granulomas. Am J Respir Crit Care Med. 2011 Oct 01; 184(7):860; author reply 860-1.Am J Respir Crit Care Med2011-10-01T00:00:002011A trojan horse strategy to deliver amikacin to mycobacterial granulomas.22033195Bai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-Deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan EDInternational immunologyBai X, Ovrutsky AR, Kartalija M, Chmura K, Kamali A, Honda JR, Oberley-Deegan RE, Dinarello CA, Crapo JD, Chang LY, Chan ED. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease. Int Immunol. 2011 Nov; 23(11):679-91.Int Immunol2011-10-27T00:00:002011IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.22046211Honda JR, Shang S, Shanley CA, Caraway ML, Henao-Tamayo M, Chan ED, Basaraba RJ, Orme IM, Ordway DJ, Flores SCThe open AIDS journalHonda JR, Shang S, Shanley CA, Caraway ML, Henao-Tamayo M, Chan ED, Basaraba RJ, Orme IM, Ordway DJ, Flores SC. Immune Responses of HIV-1 Tat Transgenic Mice to Mycobacterium Tuberculosis W-Beijing SA161. Open AIDS J. 2011; 5:86-95.Open AIDS J2011-10-19T00:00:002011Immune Responses of HIV-1 Tat Transgenic Mice to Mycobacterium Tuberculosis W-Beijing SA161.11893709Chan ED, Choi HS, Cool C, Accurso FJ, Fantuzzi GChestChan ED, Choi HS, Cool C, Accurso FJ, Fantuzzi G. Interleukin-18 expression in cystic fibrosis lungs. Chest. 2002 Mar; 121(3 Suppl):84S-85S.Chest2002-03-01T00:00:002002Interleukin-18 expression in cystic fibrosis lungs.22567269Marx GE, Chan EDTuberculosis research and treatmentMarx GE, Chan ED. Tuberculous meningitis: diagnosis and treatment overview. Tuberc Res Treat. 2011; 2011:798764.Tuberc Res Treat2011-12-21T00:00:002011Tuberculous meningitis: diagnosis and treatment overview.23475613Ovrutsky AR, Chan ED, Kartalija M, Bai X, Jackson M, Gibbs S, Falkinham JO, Iseman MD, Reynolds PR, McDonnell G, Thomas VApplied and environmental microbiologyOvrutsky AR, Chan ED, Kartalija M, Bai X, Jackson M, Gibbs S, Falkinham JO, Iseman MD, Reynolds PR, McDonnell G, Thomas V. Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata. Appl Environ Microbiol. 2013 May; 79(10):3185-92.Appl Environ Microbiol2013-03-08T00:00:002013Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata.12796214Chan MM, Chan MM, Chan EDChestChan MM, Chan MM, Chan ED. What is the effect of fingernail polish on pulse oximetry? Chest. 2003 Jun; 123(6):2163-4.Chest2003-06-01T00:00:002003What is the effect of fingernail polish on pulse oximetry?14742301Chan ED, Laurel V, Strand MJ, Chan JF, Huynh ML, Goble M, Iseman MDAmerican journal of respiratory and critical care medicineChan ED, Laurel V, Strand MJ, Chan JF, Huynh ML, Goble M, Iseman MD. Treatment and outcome analysis of 205 patients with multidrug-resistant tuberculosis. Am J Respir Crit Care Med. 2004 May 15; 169(10):1103-9.Am J Respir Crit Care Med2004-01-23T00:00:002004Treatment and outcome analysis of 205 patients with multidrug-resistant tuberculosis.16088289Chmura K, Chan ED, Noone PG, Zariwala M, Winn RA, Knowles MR, Iseman MD, Gardner EMRespiration; international review of thoracic diseasesChmura K, Chan ED, Noone PG, Zariwala M, Winn RA, Knowles MR, Iseman MD, Gardner EM. A middle-aged woman with recurrent respiratory infections. Respiration. 2005 Jul-Aug; 72(4):427-30.Respiration2005-07-01T00:00:002005A middle-aged woman with recurrent respiratory infections.16373838Sullivan A, Chmura K, Cool CD, Voelkel N, Chan EDChestSullivan A, Chmura K, Cool CD, Voelkel N, Chan ED. Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling in a fatal case. Chest. 2005 Dec; 128(6 Suppl):576S.Chest2005-12-01T00:00:002005Pulmonary capillary hemangiomatosis: an immunohistochemical analysis of vascular remodeling in a fatal case.12629012Chmura K, Lutz RD, Chiba H, Numata MS, Choi HJ, Fantuzzi G, Voelker DR, Chan EDChestChmura K, Lutz RD, Chiba H, Numata MS, Choi HJ, Fantuzzi G, Voelker DR, Chan ED. Mycoplasma pneumoniae antigens stimulate interleukin-8. Chest. 2003 Mar; 123(3 Suppl):425S.Chest2003-03-01T00:00:002003Mycoplasma pneumoniae antigens stimulate interleukin-8.12853549Chmura K, Cool C, Kircher T, Chan EDChestChmura K, Cool C, Kircher T, Chan ED. Painful lymphadenopathy and fulminant sepsis in a previously healthy 16-year-old girl. Chest. 2003 Jul; 124(1):379-82.Chest2003-07-01T00:00:002003Painful lymphadenopathy and fulminant sepsis in a previously healthy 16-year-old girl.14501961Bowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJCritical care medicineBowler RP, Velsor LW, Duda B, Chan ED, Abraham E, Ware LB, Matthay MA, Day BJ. Pulmonary edema fluid antioxidants are depressed in acute lung injury. Crit Care Med. 2003 Sep; 31(9):2309-15.Crit Care Med2003-09-01T00:00:002003Pulmonary edema fluid antioxidants are depressed in acute lung injury.14532196Bastien N, Ward D, Van Caeseele P, Brandt K, Lee SH, McNabb G, Klisko B, Chan E, Li YJournal of clinical microbiologyBastien N, Ward D, Van Caeseele P, Brandt K, Lee SH, McNabb G, Klisko B, Chan E, Li Y. Human metapneumovirus infection in the Canadian population. J Clin Microbiol. 2003 Oct; 41(10):4642-6.J Clin Microbiol2003-10-01T00:00:002003Human metapneumovirus infection in the Canadian population.15136460Bowler RP, Duda B, Vu KO, Byers T, Franklin W, Chan ED, Miller YEChestBowler RP, Duda B, Vu KO, Byers T, Franklin W, Chan ED, Miller YE. Airway antioxidants and oxidative stress as predictors of sputum atypia and airflow obstruction. Chest. 2004 May; 125(5 Suppl):127S-8S.Chest2004-05-01T00:00:002004Airway antioxidants and oxidative stress as predictors of sputum atypia and airflow obstruction.15525561Bai X, Wilson SE, Chmura K, Feldman NE, Chan EDTuberculosis (Edinburgh, Scotland)Bai X, Wilson SE, Chmura K, Feldman NE, Chan ED. Morphometric analysis of Th(1) and Th(2) cytokine expression in human pulmonary tuberculosis. Tuberculosis (Edinb). 2004; 84(6):375-85.Tuberculosis (Edinb)2004-01-01T00:00:002004Morphometric analysis of Th(1) and Th(2) cytokine expression in human pulmonary tuberculosis.15539746Winn RA, Chan ED, Langmack EL, Kotaru C, Aronsen EChestWinn RA, Chan ED, Langmack EL, Kotaru C, Aronsen E. Dysphagia, chest pain, and refractory asthma in a 42-year-old woman. Chest. 2004 Nov; 126(5):1694-7.Chest2004-11-01T00:00:002004Dysphagia, chest pain, and refractory asthma in a 42-year-old woman.15603056Gruber MP, Nana-Sinkam SP, Chan EDRespiratory careGruber MP, Nana-Sinkam SP, Chan ED. Airflow limitation and dynamic gas trapping in a bone marrow transplant recipient. Respir Care. 2004 Dec; 49(12):1542-5.Respir Care2004-12-01T00:00:002004Airflow limitation and dynamic gas trapping in a bone marrow transplant recipient.18310351Ordway D, Henao-Tamayo M, Smith E, Shanley C, Harton M, Troudt J, Bai X, Basaraba RJ, Orme IM, Chan EDJournal of leukocyte biologyOrdway D, Henao-Tamayo M, Smith E, Shanley C, Harton M, Troudt J, Bai X, Basaraba RJ, Orme IM, Chan ED. Animal model of Mycobacterium abscessus lung infection. J Leukoc Biol. 2008 Jun; 83(6):1502-11.J Leukoc Biol2008-02-29T00:00:002008Animal model of Mycobacterium abscessus lung infection.18487355Chmura K, Bai X, Nakamura M, Kandasamy P, McGibney M, Kuronuma K, Mitsuzawa H, Voelker DR, Chan EDAmerican journal of physiology. Lung cellular and molecular physiologyChmura K, Bai X, Nakamura M, Kandasamy P, McGibney M, Kuronuma K, Mitsuzawa H, Voelker DR, Chan ED. Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells. Am J Physiol Lung Cell Mol Physiol. 2008 Jul; 295(1):L220-30.Am J Physiol Lung Cell Mol Physiol2008-05-16T00:00:002008Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells.19556165Morris KR, Lutz RD, Bai X, McGibney MT, Cook D, Ordway D, Chan EDTuberculosis (Edinburgh, Scotland)Morris KR, Lutz RD, Bai X, McGibney MT, Cook D, Ordway D, Chan ED. Suppression of IFNgamma+mycobacterial lipoarabinomannan-induced NO by IL-4 is due to decreased IRF-1 expression. Tuberculosis (Edinb). 2009 Jul; 89(4):294-303.Tuberculosis (Edinb)2009-06-24T00:00:002009Suppression of IFNgamma+mycobacterial lipoarabinomannan-induced NO by IL-4 is due to decreased IRF-1 expression.19584052Kuronuma K, Mitsuzawa H, Takeda K, Nishitani C, Chan ED, Kuroki Y, Nakamura M, Voelker DRThe Journal of biological chemistryKuronuma K, Mitsuzawa H, Takeda K, Nishitani C, Chan ED, Kuroki Y, Nakamura M, Voelker DR. Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2. J Biol Chem. 2009 Sep 18; 284(38):25488-500.J Biol Chem2009-07-07T00:00:002009Anionic pulmonary surfactant phospholipids inhibit inflammatory responses from alveolar macrophages and U937 cells by binding the lipopolysaccharide-interacting proteins CD14 and MD-2.17306883Morimoto Y, Chan ED, Heifets L, Routes JMThe Journal of infectionMorimoto Y, Chan ED, Heifets L, Routes JM. Pulmonary infection with Mycobacterium neoaurum identified by 16S ribosomal DNA sequence. J Infect. 2007 Apr; 54(4):e227-31.J Infect2007-02-15T00:00:002007Pulmonary infection with Mycobacterium neoaurum identified by 16S ribosomal DNA sequence.19809061Bedient TJ, Schwarz MI, Groshong SD, Chan EDChestBedient TJ, Schwarz MI, Groshong SD, Chan ED. A 45-year-old man with a history of hepatitis C and testicular cancer presents with cavitary lung lesions and palpable purpura. Chest. 2009 Oct; 136(4):1168-1174.Chest2009-10-01T00:00:002009A 45-year-old man with a history of hepatitis C and testicular cancer presents with cavitary lung lesions and palpable purpura.20081053Chan ED, Bai X, Kartalija M, Orme IM, Ordway DJAmerican journal of respiratory cell and molecular biologyChan ED, Bai X, Kartalija M, Orme IM, Ordway DJ. Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease. Am J Respir Cell Mol Biol. 2010 Oct; 43(4):387-93.Am J Respir Cell Mol Biol2010-01-15T00:00:002010Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease.18367746Chan EDThe New England journal of medicineChan ED. Corticosteroids for bacterial meningitis. N Engl J Med. 2008 Mar 27; 358(13):1399; author reply 1400-1.N Engl J Med2008-03-27T00:00:002008Corticosteroids for bacterial meningitis.18594121Chan ED, Iseman MDAmerican journal of respiratory and critical care medicineChan ED, Iseman MD. Significance of bronchiectasis in patients with alpha1-antitrypsin deficiency. Am J Respir Crit Care Med. 2008 Jul 15; 178(2):208; author reply 208-9.Am J Respir Crit Care Med2008-07-15T00:00:002008Significance of bronchiectasis in patients with alpha1-antitrypsin deficiency.20947905Chan ED, Keane J, Iseman MDAmerican journal of respiratory and critical care medicineChan ED, Keane J, Iseman MD. Should cigarette smoke exposure be a criterion to treat latent tuberculous infection? Am J Respir Crit Care Med. 2010 Oct 15; 182(8):990-2.Am J Respir Crit Care Med2010-10-15T00:00:002010Should cigarette smoke exposure be a criterion to treat latent tuberculous infection?20973980Mor? JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RPBMC pulmonary medicineMor? JM, Voelker DR, Silveira LJ, Edwards MG, Chan ED, Bowler RP. Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease. BMC Pulm Med. 2010 Oct 25; 10:53.BMC Pulm Med2010-10-25T00:00:002010Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease.19097985Oberley-Deegan RE, Lee YM, Morey GE, Cook DM, Chan ED, Crapo JDAmerican journal of respiratory cell and molecular biologyOberley-Deegan RE, Lee YM, Morey GE, Cook DM, Chan ED, Crapo JD. The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus. Am J Respir Cell Mol Biol. 2009 Aug; 41(2):170-8.Am J Respir Cell Mol Biol2008-12-18T00:00:002008The antioxidant mimetic, MnTE-2-PyP, reduces intracellular growth of Mycobacterium abscessus.19191632Chan ED, Strand MJ, Iseman MDClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaChan ED, Strand MJ, Iseman MD. Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB. Clin Infect Dis. 2009 Mar 01; 48(5):e50-2.Clin Infect Dis2009-03-01T00:00:002009Multidrug-resistant tuberculosis (TB) resistant to fluoroquinolones and streptomycin but susceptible to second-line injection therapy has a better prognosis than extensively drug-resistant TB.21205826Kandasamy P, Zarini S, Chan ED, Leslie CC, Murphy RC, Voelker DRThe Journal of biological chemistryKandasamy P, Zarini S, Chan ED, Leslie CC, Murphy RC, Voelker DR. Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages. J Biol Chem. 2011 Mar 11; 286(10):7841-7853.J Biol Chem2011-01-04T00:00:002011Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages.20190143Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan EDJournal of immunology (Baltimore, Md. : 1950)Bai X, Kim SH, Azam T, McGibney MT, Huang H, Dinarello CA, Chan ED. IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages. J Immunol. 2010 Apr 01; 184(7):3830-40.J Immunol2010-02-26T00:00:002010IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages.20670714Gingo M, Risbano MG, Russ PD, Chan EDThe American journal of medicineGingo M, Risbano MG, Russ PD, Chan ED. Not your otitis media 101. Am J Med. 2010 Aug; 123(8):e9-e11.Am J Med2010-08-01T00:00:002010Not your otitis media 101.21167783Bai X, Chmura K, Ovrutsky AR, Bowler RP, Scheinman RI, Oberley-Deegan RE, Liu H, Shang S, Ordway D, Chan EDTuberculosis (Edinburgh, Scotland)Bai X, Chmura K, Ovrutsky AR, Bowler RP, Scheinman RI, Oberley-Deegan RE, Liu H, Shang S, Ordway D, Chan ED. Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription. Tuberculosis (Edinb). 2011 Jan; 91(1):26-35.Tuberculosis (Edinb)2010-12-16T00:00:002010Mycobacterium tuberculosis increases IP-10 and MIG protein despite inhibition of IP-10 and MIG transcription.23460011Chan ED, Iseman MDSeminars in respiratory and critical care medicineChan ED, Iseman MD. Underlying host risk factors for nontuberculous mycobacterial lung disease. Semin Respir Crit Care Med. 2013 Feb; 34(1):110-23.Semin Respir Crit Care Med2013-03-04T00:00:002013Underlying host risk factors for nontuberculous mycobacterial lung disease.23490227Chan ED, Chan MM, Chan MMRespiratory medicineChan ED, Chan MM, Chan MM. Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations. Respir Med. 2013 Jun; 107(6):789-99.Respir Med2013-03-13T00:00:002013Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations.23575341Chan ED, Iseman MDThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung DiseaseChan ED, Iseman MD. Surgery for MDR-TB? Int J Tuberc Lung Dis. 2013 May; 17(5):710.Int J Tuberc Lung Dis2013-05-01T00:00:002013Surgery for MDR-TB?23634218Bai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan EDPloS oneBai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan ED. Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages. PLoS One. 2013; 8(4):e61925.PLoS One2013-04-25T00:00:002013Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages.23734642Talbert J, Chan EDExpert review of respiratory medicineTalbert J, Chan ED. The association between body shape and nontuberculous mycobacterial lung disease. Expert Rev Respir Med. 2013 Jun; 7(3):201-4.Expert Rev Respir Med2013-06-01T00:00:002013The association between body shape and nontuberculous mycobacterial lung disease.22458269Walter ND, Strong M, Belknap R, Ordway DJ, Daley CL, Chan EDRespirology (Carlton, Vic.)Walter ND, Strong M, Belknap R, Ordway DJ, Daley CL, Chan ED. Translating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosis. Respirology. 2012 Jul; 17(5):772-91.Respirology2012-07-01T00:00:002012Translating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosis.22975343Chan ED, Pott GB, Silkoff PE, Ralston AH, Bryan CL, Shapiro LJournal of leukocyte biologyChan ED, Pott GB, Silkoff PE, Ralston AH, Bryan CL, Shapiro L. Alpha-1-antitrypsin inhibits nitric oxide production. J Leukoc Biol. 2012 Dec; 92(6):1251-60.J Leukoc Biol2012-09-13T00:00:002012Alpha-1-antitrypsin inhibits nitric oxide production.23144328Kartalija M, Ovrutsky AR, Bryan CL, Pott GB, Fantuzzi G, Thomas J, Strand MJ, Bai X, Ramamoorthy P, Rothman MS, Nagabhushanam V, McDermott M, Levin AR, Frazer-Abel A, Giclas PC, Korner J, Iseman MD, Shapiro L, Chan EDAmerican journal of respiratory and critical care medicineKartalija M, Ovrutsky AR, Bryan CL, Pott GB, Fantuzzi G, Thomas J, Strand MJ, Bai X, Ramamoorthy P, Rothman MS, Nagabhushanam V, McDermott M, Levin AR, Frazer-Abel A, Giclas PC, Korner J, Iseman MD, Shapiro L, Chan ED. Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes. Am J Respir Crit Care Med. 2013 Jan 15; 187(2):197-205.Am J Respir Crit Care Med2012-11-09T00:00:002012Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes.23451220Malcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, Bratton DL, Taylor-Cousar JL, Nichols DP, Saavedra MT, Nick JAPloS oneMalcolm KC, Nichols EM, Caceres SM, Kret JE, Martiniano SL, Sagel SD, Chan ED, Caverly L, Solomon GM, Reynolds P, Bratton DL, Taylor-Cousar JL, Nichols DP, Saavedra MT, Nick JA. Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival. PLoS One. 2013; 8(2):e57402.PLoS One2013-02-25T00:00:002013Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival.Authorship 175710329388833Honda JR, Bai X, Chan EDAmerican journal of respiratory cell and molecular biologyHonda JR, Bai X, Chan ED. Elucidating the Pathogenesis of Nontuberculous Mycobacterial Lung Disease: Lesson from the Six Blind Men and the Elephant. Am J Respir Cell Mol Biol. 2018 02; 58(2):142-143.Am J Respir Cell Mol Biol2018-02-01T00:00:002018Elucidating the Pathogenesis of Nontuberculous Mycobacterial Lung Disease: Lesson from the Six Blind Men and the Elephant.Authorship 1775001029483288Gomes RS, Silva MVT, Dos Santos JC, van Linge C, Reis JM, Teixeira MM, Pinto SA, Dorta ML, Bai X, Chan ED, Dinarello CA, Oliveira MAP, Joosten LAB, Ribeiro-Dias FInfection and immunityGomes RS, Silva MVT, Dos Santos JC, van Linge C, Reis JM, Teixeira MM, Pinto SA, Dorta ML, Bai X, Chan ED, Dinarello CA, Oliveira MAP, Joosten LAB, Ribeiro-Dias F. Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice. Infect Immun. 2018 05; 86(5).Infect Immun2018-04-23T00:00:002018Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.2021-09-30NIHCHAN, EDWARD D2017-10-01How Does Nicotine Impair Macrophage Killing of Mycobacterium Tuberculosis? I01CX001452Principal InvestigatorAuthorship 1833731Authorship 183541429936307Honda JR, Alper S, Bai X, Chan EDCurrent opinion in immunologyHonda JR, Alper S, Bai X, Chan ED. Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections. Curr Opin Immunol. 2018 10; 54:66-73.Curr Opin Immunol2018-06-21T00:00:002018Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infections.29957052Chan EDAmerican journal of respiratory cell and molecular biologyChan ED. Reduced IFN-? in Patients with Pulmonary Nontuberculous Mycobacterial Disease: Potentially Multiple Causes. Am J Respir Cell Mol Biol. 2018 07; 59(1):130-131.Am J Respir Cell Mol Biol2018-07-01T00:00:002018Reduced IFN-? in Patients with Pulmonary Nontuberculous Mycobacterial Disease: Potentially Multiple Causes.D009169Living Beings893040.762712Mycobacterium tuberculosisAuthorship 18384213Authorship 1839425Authorship 184229129991410Chan EDThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung DiseaseChan ED. Thin body habitus is a risk factor for active pulmonary tuberculosis, but not for infection. Int J Tuberc Lung Dis. 2018 08 01; 22(8):967-968.Int J Tuberc Lung Dis2018-08-01T00:00:002018Thin body habitus is a risk factor for active pulmonary tuberculosis, but not for infection.29995958Harausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T, Seddon JA, Menzies D, Turkova A, Achar J, Amanullah F, Barry P, Becerra M, Chan ED, Chan PC, Ioana Chiotan D, Crossa A, Drobac PC, Fairlie L, Falzon D, Flood J, Gegia M, Hicks RM, Isaakidis P, Kadri SM, Kampmann B, Madhi SA, Marais E, Mariandyshev A, M?ndez-Echevarr?a A, Moore BK, Nargiza P, Ozere I, Padayatchi N, Ur-Rehman S, Rybak N, Santiago-Garcia B, Shah NS, Sharma S, Shim TS, Skrahina A, Soriano-Arandes A, van den Boom M, van der Werf MJ, van der Werf TS, Williams B, Yablokova E, Yim JJ, Furin J, Hesseling ACPLoS medicineHarausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T, Seddon JA, Menzies D, Turkova A, Achar J, Amanullah F, Barry P, Becerra M, Chan ED, Chan PC, Ioana Chiotan D, Crossa A, Drobac PC, Fairlie L, Falzon D, Flood J, Gegia M, Hicks RM, Isaakidis P, Kadri SM, Kampmann B, Madhi SA, Marais E, Mariandyshev A, M?ndez-Echevarr?a A, Moore BK, Nargiza P, Ozere I, Padayatchi N, Ur-Rehman S, Rybak N, Santiago-Garcia B, Shah NS, Sharma S, Shim TS, Skrahina A, Soriano-Arandes A, van den Boom M, van der Werf MJ, van der Werf TS, Williams B, Yablokova E, Yim JJ, Furin J, Hesseling AC. Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis. PLoS Med. 2018 07; 15(7):e1002591.PLoS Med2018-07-11T00:00:002018Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis.29984040Bai X, Aerts SL, Verma D, Ordway DJ, Chan EDImmune networkBai X, Aerts SL, Verma D, Ordway DJ, Chan ED. Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis. Immune Netw. 2018 Jun; 18(3):e22.Immune Netw2018-06-26T00:00:002018Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis.Authorship 1847064Authorship 184855230036298Holt MR, Chan EDJournal of thoracic imagingHolt MR, Chan ED. Chronic Cavitary Infections Other than Tuberculosis: Clinical Aspects. J Thorac Imaging. 2018 Sep; 33(5):322-333.J Thorac Imaging2018-09-01T00:00:002018Chronic Cavitary Infections Other than Tuberculosis: Clinical Aspects.30048346Ketai L, Currie BJ, Holt MR, Chan EDJournal of thoracic imagingKetai L, Currie BJ, Holt MR, Chan ED. Radiology of Chronic Cavitary Infections. J Thorac Imaging. 2018 Sep; 33(5):334-343.J Thorac Imaging2018-09-01T00:00:002018Radiology of Chronic Cavitary Infections.Authorship 18829223Authorship 188303330215381Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fr?chet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Labor?n R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies DLancet (London, England)Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fr?chet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Labor?n R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet. 2018 09 08; 392(10150):821-834.Lancet2018-09-08T00:00:002018Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.30214436Honda JR, Virdi R, Chan EDFrontiers in microbiologyHonda JR, Virdi R, Chan ED. Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches. Front Microbiol. 2018; 9:2029.Front Microbiol2018-08-30T00:00:002018Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches.D009165Disorders743340.68253Mycobacterium Infections, NontuberculousAuthorship 190558730377276Gebert MJ, Delgado-Baquerizo M, Oliverio AM, Webster TM, Nichols LM, Honda JR, Chan ED, Adjemian J, Dunn RR, Fierer NmBioGebert MJ, Delgado-Baquerizo M, Oliverio AM, Webster TM, Nichols LM, Honda JR, Chan ED, Adjemian J, Dunn RR, Fierer N. Ecological Analyses of Mycobacteria in Showerhead Biofilms and Their Relevance to Human Health. mBio. 2018 10 30; 9(5).mBio2018-10-30T00:00:002018Ecological Analyses of Mycobacteria in Showerhead Biofilms and Their Relevance to Human Health.GenevieveBoddieGenevieve Boddie39.74515960000000-104.8406280000000015145Boddie, GenevieveInstructorD009170Living Beings422050.821694Nontuberculous MycobacteriaAuthorship 198657330948183Tran T, Bonham AJ, Chan ED, Honda JRTuberculosis (Edinburgh, Scotland)Tran T, Bonham AJ, Chan ED, Honda JR. A paucity of knowledge regarding nontuberculous mycobacterial lipids compared to the tubercle bacillus. Tuberculosis (Edinb). 2019 03; 115:96-107.Tuberculosis (Edinb)2019-02-28T00:00:002019A paucity of knowledge regarding nontuberculous mycobacterial lipids compared to the tubercle bacillus.Authorship 199159631001241Verma D, Stapleton M, Gadwa J, Vongtongsalee K, Schenkel AR, Chan ED, Ordway DFrontiers in microbiologyVerma D, Stapleton M, Gadwa J, Vongtongsalee K, Schenkel AR, Chan ED, Ordway D. Mycobacterium avium Infection in a C3HeB/FeJ Mouse Model. Front Microbiol. 2019; 10:693.Front Microbiol2019-04-03T00:00:002019Mycobacterium avium Infection in a C3HeB/FeJ Mouse Model.Authorship 200519431094592Marras TK, Mirsaeidi M, Vinnard C, Chan ED, Eagle G, Zhang R, Wang P, Zhang QJournal of medical economicsMarras TK, Mirsaeidi M, Vinnard C, Chan ED, Eagle G, Zhang R, Wang P, Zhang Q. Guidelines-based treatment associated with improved economic outcomes in nontuberculous mycobacterial lung disease. J Med Econ. 2019 Nov; 22(11):1126-1133.J Med Econ2019-06-10T00:00:002019Guidelines-based treatment associated with improved economic outcomes in nontuberculous mycobacterial lung disease.Authorship 201577631167948Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL, Montoya DJ, Modlin RL, Liu PTmSphereKim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL, Montoya DJ, Modlin RL, Liu PT. Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. mSphere. 2019 06 05; 4(3).mSphere2019-06-05T00:00:002019Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis.PUL GENERAL OPERATIONSD008171Disorders3037640.595875Lung DiseasesAuthorship 2040191131293581Bai X, Bai A, Honda JR, Eichstaedt C, Musheyev A, Feng Z, Huitt G, Harbeck R, Kosmider B, Sandhaus RA, Chan EDFrontiers in immunologyBai X, Bai A, Honda JR, Eichstaedt C, Musheyev A, Feng Z, Huitt G, Harbeck R, Kosmider B, Sandhaus RA, Chan ED. Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria. Front Immunol. 2019; 10:1417.Front Immunol2019-06-26T00:00:002019Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria.D014376Disorders782660.771771TuberculosisSOM-MEDClinical ImmunologyInfectious DiseaseUniversity of Colorado Denver - Anschutz Medical Campus6.879720.00655707711research areas15.06140.01838187coauthor of299.93818.053260similar to11183selected publicationsBrianFreedBrian M Freed39.74528180000000-104.83757270000000187Freed, BrianProfessorJenniferHondaJennifer R. Honda39.74515960000000-104.840628000000001887Honda, JenniferAffiliate - NJHCharlesDinarelloCharles A Dinarello39.74528180000000-104.8375727000000023Dinarello, CharlesDistinguished ProfessorXiyuanBaiXiyuan Bai39.74515960000000-104.840628000000003050Bai, XiyuanAssoc Professor-ResearchJerryNickJerry Allan Nick39.74528180000000-104.837572700000004422Nick, JerryAsst ProfessorCharlesDaleyCharles L Daley39.74515960000000-104.840628000000004879Daley, CharlesAffiliate - NJHLelandShapiroLeland Shapiro39.74528180000000-104.8375727000000024Shapiro, LelandAssociate ProfessorAuthorship 205269531398626Damen MSMA, Ballak D, Sapinsley Z, Bai X, Chan ED, Seals DR, Popa CD, Joosten LABCytokineDamen MSMA, Ballak D, Sapinsley Z, Bai X, Chan ED, Seals DR, Popa CD, Joosten LAB. Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes. Cytokine. 2020 01; 125:154793.Cytokine2019-08-06T00:00:002019Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes.Authorship 122216Authorship 2089891831545652Honda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan EDAmerican journal of respiratory cell and molecular biologyHonda JR, Hess T, Carlson R, Kandasamy P, Nieto Ramirez LM, Norton GJ, Virdi R, Islam MN, Mehaffy C, Hasan NA, Epperson LE, Hesser D, Alper S, Strong M, Flores SC, Voelker DR, Dobos KM, Chan ED. Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37. Am J Respir Cell Mol Biol. 2020 03; 62(3):354-363.Am J Respir Cell Mol Biol2020-03-01T00:00:002020Nontuberculous Mycobacteria Show Differential Infectivity and Use Phospholipids to Antagonize LL-37.Authorship 99158923808720Ovrutsky AR, Merkel PA, Schonteich E, Bai X, Kinney W, Iseman MD, Kartalija M, Knight V, Chan EDScandinavian journal of infectious diseasesOvrutsky AR, Merkel PA, Schonteich E, Bai X, Kinney W, Iseman MD, Kartalija M, Knight V, Chan ED. Patients with non-tuberculous mycobacterial lung disease have elevated transforming growth factor-beta following ex vivo stimulation of blood with live Mycobacterium intracellulare. Scand J Infect Dis. 2013 Sep; 45(9):711-4.Scand J Infect Dis2013-07-01T00:00:002013Patients with non-tuberculous mycobacterial lung disease have elevated transforming growth factor-beta following ex vivo stimulation of blood with live Mycobacterium intracellulare.Authorship 210195131626870Chan ED, Chan MM, Chan MM, Marik PEPharmacology & therapeuticsChan ED, Chan MM, Chan MM, Marik PE. Use of glucocorticoids in the critical care setting: Science and clinical evidence. Pharmacol Ther. 2020 02; 206:107428.Pharmacol Ther2019-10-15T00:00:002019Use of glucocorticoids in the critical care setting: Science and clinical evidence.Authorship 131524Authorship 134725Authorship 1358611Authorship 214363331903275Choi S, Richards JC, Chan EDJournal of thoracic diseaseChoi S, Richards JC, Chan ED. Can physics principles help explain why non-tuberculous mycobacterial lung disease is more severe in the right middle lobe and lingula? J Thorac Dis. 2019 Nov; 11(11):4847-4854.J Thorac Dis2019-11-01T00:00:002019Can physics principles help explain why non-tuberculous mycobacterial lung disease is more severe in the right middle lobe and lingula?Authorship 217534932117140Feng Z, Bai X, Wang T, Garcia C, Bai A, Li L, Honda JR, Nie X, Chan EDFrontiers in microbiologyFeng Z, Bai X, Wang T, Garcia C, Bai A, Li L, Honda JR, Nie X, Chan ED. Differential Responses by Human Macrophages to Infection With Mycobacterium tuberculosis and Non-tuberculous Mycobacteria. Front Microbiol. 2020; 11:116.Front Microbiol2020-02-07T00:00:002020Differential Responses by Human Macrophages to Infection With Mycobacterium tuberculosis and Non-tuberculous Mycobacteria.Authorship 219258332298605Dawrs SN, Kautz M, Chan ED, Honda JRAmerican journal of respiratory and critical care medicineDawrs SN, Kautz M, Chan ED, Honda JR. Mycobacteriumabscessus and Gastroesophageal Reflux: An In Vitro Study. Am J Respir Crit Care Med. 2020 08 01; 202(3):466-469.Am J Respir Crit Care Med2020-08-01T00:00:002020Mycobacteriumabscessus and Gastroesophageal Reflux: An In Vitro Study.Authorship 221258132497414Chan ED, Verma D, Ordway DJCurrent protocols in immunologyChan ED, Verma D, Ordway DJ. Animal Models of Mycobacteria Infection. Curr Protoc Immunol. 2020 06; 129(1):e98.Curr Protoc Immunol2020-06-01T00:00:002020Animal Models of Mycobacteria Infection.Authorship 222214432586878Kwak N, Winters N, Campbell JR, Chan ED, Gegia M, Lange C, Lee M, Milanov V, Menzies D, Yim JJThe European respiratory journalKwak N, Winters N, Campbell JR, Chan ED, Gegia M, Lange C, Lee M, Milanov V, Menzies D, Yim JJ. Changes in treatment for multidrug-resistant tuberculosis according to national income. Eur Respir J. 2020 11; 56(5).Eur Respir J2020-11-05T00:00:002020Changes in treatment for multidrug-resistant tuberculosis according to national income.Authorship 223842132642083Chan EDJournal of thoracic diseaseChan ED. Are there common threads in the susceptibility to cancer and tuberculosis? J Thorac Dis. 2020 May; 12(5):1776-1780.J Thorac Dis2020-05-01T00:00:002020Are there common threads in the susceptibility to cancer and tuberculosis?Authorship 2245791Authorship 2246414Authorship 224605732706544Chan ED, Majluf-Cruz AThe New England journal of medicineChan ED, Majluf-Cruz A. Hereditary Angioedema. N Engl J Med. 2020 07 23; 383(4):e20.N Engl J Med2020-07-23T00:00:002020Hereditary Angioedema.32694392Yiang GT, Tzeng IS, Shui HA, Wu MY, Peng MY, Chan CY, Chan ED, Wu YK, Lan CC, Yang MC, Huang KL, Wu CW, Chang CH, Su WLShock (Augusta, Ga.)Yiang GT, Tzeng IS, Shui HA, Wu MY, Peng MY, Chan CY, Chan ED, Wu YK, Lan CC, Yang MC, Huang KL, Wu CW, Chang CH, Su WL. Early Screening of Risk for Multidrug-Resistant Organisms in the Emergency Department in Patients With Pneumonia and Early Septic Shock: Single-Center, Retrospective Cohort Study. Shock. 2021 02 01; 55(2):198-209.Shock2021-02-01T00:00:002021Early Screening of Risk for Multidrug-Resistant Organisms in the Emergency Department in Patients With Pneumonia and Early Septic Shock: Single-Center, Retrospective Cohort Study.29977464Brown JK, Singh K, Dumitru R, Chan E, Kim MPMethodist DeBakey cardiovascular journalBrown JK, Singh K, Dumitru R, Chan E, Kim MP. The Benefits of Enhanced Recovery After Surgery Programs and Their Application in Cardiothoracic Surgery. Methodist Debakey Cardiovasc J. 2018 Apr-Jun; 14(2):77-88.Methodist Debakey Cardiovasc J2018-04-01T00:00:002018The Benefits of Enhanced Recovery After Surgery Programs and Their Application in Cardiothoracic Surgery.Authorship 226468832859599Glickman CM, Virdi R, Hasan NA, Epperson LE, Brown L, Dawrs SN, Crooks JL, Chan ED, Strong M, Nelson ST, Honda JRApplied and environmental microbiologyGlickman CM, Virdi R, Hasan NA, Epperson LE, Brown L, Dawrs SN, Crooks JL, Chan ED, Strong M, Nelson ST, Honda JR. Assessment of Soil Features on the Growth of Environmental Nontuberculous Mycobacterial Isolates from Hawai'i. Appl Environ Microbiol. 2020 10 15; 86(21).Appl Environ Microbiol2020-10-15T00:00:002020Assessment of Soil Features on the Growth of Environmental Nontuberculous Mycobacterial Isolates from Hawai'i.Authorship 227751632895617King M, Hurley H, Davidson KR, Dempsey EC, Barron MA, Chan ED, Frey AImmune networkKing M, Hurley H, Davidson KR, Dempsey EC, Barron MA, Chan ED, Frey A. The Link between Fusobacteria and Colon Cancer: a Fulminant Example and Review of the Evidence. Immune Netw. 2020 Aug; 20(4):e30.Immune Netw2020-08-04T00:00:002020The Link between Fusobacteria and Colon Cancer: a Fulminant Example and Review of the Evidence.Authorship 2286161133035706Honda JR, Chan YL, Tong EI, Kawatachi M, Virdi R, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Crooks JT, Chan ED, Strong MMicrobes and infectionHonda JR, Chan YL, Tong EI, Kawatachi M, Virdi R, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Crooks JT, Chan ED, Strong M. Inaugural nontuberculous mycobacterial lung disease education and research conference, Honolulu, Hawai'i, February 1-2, 2020. Microbes Infect. 2021 Jan-Feb; 23(1):104763.Microbes Infect2020-10-06T00:00:002020Inaugural nontuberculous mycobacterial lung disease education and research conference, Honolulu, Hawai'i, February 1-2, 2020.Authorship 2306084Authorship 23045711Authorship 23119014Authorship 2302783Authorship 2328133Authorship 2335861Authorship 2336691Authorship 231267233145070Moon P, Guillaumin E, Chan EDJournal of thoracic diseaseMoon P, Guillaumin E, Chan ED. Non-tuberculous mycobacterial lung disease due to multiple "minor" risk factors: an illustrative case and a review of these "lesser elements". J Thorac Dis. 2020 Sep; 12(9):4960-4972.J Thorac Dis2020-09-01T00:00:002020Non-tuberculous mycobacterial lung disease due to multiple "minor" risk factors: an illustrative case and a review of these "lesser elements".33163249Kim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim SImmune networkKim S, Lee JH, Lee S, Shim S, Nguyen TT, Hwang J, Kim H, Choi YO, Hong J, Bae S, Jhun H, Yum H, Lee Y, Chan ED, Yu L, Azam T, Kim YD, Yeom SC, Yoo KH, Kang LW, Shin KC, Kim S. The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene. Immune Netw. 2020 Oct; 20(5):e41.Immune Netw2020-10-26T00:00:002020The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene.33239231Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan EDMedical hypothesesBai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan; 146:110394.Med Hypotheses2020-11-12T00:00:002020Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19.33317928Chan ED, Bai XTuberculosis (Edinburgh, Scotland)Chan ED, Bai X. Further evidence that cigarette smoke and nicotine compromise host immunity against tuberculosis (invited editorial). Tuberculosis (Edinb). 2021 03; 127:102035.Tuberculosis (Edinb)2020-12-02T00:00:002020Further evidence that cigarette smoke and nicotine compromise host immunity against tuberculosis (invited editorial).33326358Ha DM, Zeng C, Chan ED, Gray M, Mazzone PJ, Samet JM, Steiner JFAnnals of the American Thoracic SocietyHa DM, Zeng C, Chan ED, Gray M, Mazzone PJ, Samet JM, Steiner JF. Association of Exercise Behavior with Overall Survival in Stage I-IIIA Lung Cancer. Ann Am Thorac Soc. 2021 06; 18(6):1034-1042.Ann Am Thorac Soc2021-06-01T00:00:002021Association of Exercise Behavior with Overall Survival in Stage I-IIIA Lung Cancer.33145073Davidson KR, Ha DM, Schwarz MI, Chan EDJournal of thoracic diseaseDavidson KR, Ha DM, Schwarz MI, Chan ED. Bronchoalveolar lavage as a diagnostic procedure: a review of known cellular and molecular findings in various lung diseases. J Thorac Dis. 2020 Sep; 12(9):4991-5019.J Thorac Dis2020-09-01T00:00:002020Bronchoalveolar lavage as a diagnostic procedure: a review of known cellular and molecular findings in various lung diseases.33207695Verma D, Chan ED, Ordway DJVaccinesVerma D, Chan ED, Ordway DJ. Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions. Vaccines (Basel). 2020 Nov 16; 8(4).Vaccines (Basel)2020-11-16T00:00:002020Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions.33357169Chan ED, Majluf-Cruz AAmerican journal of respiratory and critical care medicineChan ED, Majluf-Cruz A. Is the Angioedema Associated with COVID-19 a Real Entity, a Mimic, or Both? 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Chest. 2021 01; 159(1):e35-e38.Chest2021-01-01T00:00:002021A 28-Year-Old Man With Chest Pain, Shortness of Breath, and Hemoptysis After Recovery From Coronavirus Disease 2019 Pneumonia.33431432Hasan NA, Norton GJ, Virdi R, Epperson LE, Vang CK, Hellbusch B, Bai X, Chan ED, Strong M, Honda JRJournal of bacteriologyHasan NA, Norton GJ, Virdi R, Epperson LE, Vang CK, Hellbusch B, Bai X, Chan ED, Strong M, Honda JR. Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in macrophages. J Bacteriol. 2021 03 15; 203(6).J Bacteriol2021-01-11T00:00:002021Measurable genomic changes in Mycobacterium avium subsp. hominissuis after long-term adaptation in Acanthamoeba lenticulata and reduced persistence in macrophages.33440182Weingart MF, Li Q, Choi S, Maleki-Fischbach M, Kwon YS, Koelsch T, Dow CT, Truong TQ, Chan EDChestWeingart MF, Li Q, Choi S, Maleki-Fischbach M, Kwon YS, Koelsch T, Dow CT, Truong TQ, Chan ED. Analysis of Non-TB Mycobacterial Lung Disease in Patients With Primary Sj?gren's Syndrome at a Referral Center. Chest. 2021 06; 159(6):2218-2221.Chest2021-01-10T00:00:002021Analysis of Non-TB Mycobacterial Lung Disease in Patients With Primary Sj?gren's Syndrome at a Referral Center.33499212Virdi R, Lowe ME, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Glickman CM, Chan ED, Strong M, Crooks JL, Honda JRMicroorganismsVirdi R, Lowe ME, Norton GJ, Dawrs SN, Hasan NA, Epperson LE, Glickman CM, Chan ED, Strong M, Crooks JL, Honda JR. 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Asian Pac J Cancer Prev. 2020 Sep 01; 21(9):2623-2629.Asian Pac J Cancer Prev2020-09-01T00:00:002020Reading High Breast Density Mammograms: Differences in Diagnostic Performance between Radiologists from Hong Kong SAR/Guangdong Province in China and Australia.33634249Grayeb DE, Chan ED, Swanson LM, Gibson DG, Mehler PSAME case reportsGrayeb DE, Chan ED, Swanson LM, Gibson DG, Mehler PS. Nontuberculous mycobacterial lung infections in patients with eating disorders: plausible mechanistic links in a case series. AME Case Rep. 2021; 5:9.AME Case Rep2021-01-25T00:00:002021Nontuberculous mycobacterial lung infections in patients with eating disorders: plausible mechanistic links in a case series.33634751Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-G?mez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, ?lvarez ?MC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Ant?n Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Ara?jo WL, Araya J, Arden C, Ar?valo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnaun?-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, ?valos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, B?nr?ti ?, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Baril? 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C, Cao B, Caraglia M, Caram?s B, Carchman EH, Cardenal-Mu?oz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et alAutophagyKlionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-G?mez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, ?lvarez ?MC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Ant?n Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Ara?jo WL, Araya J, Arden C, Ar?valo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnaun?-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, ?valos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, B?nr?ti ?, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Baril? D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touz? N, Bellarosa C, Belleudi F, Bell? P?rez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Bur?n MI, Bustos V, B?ttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cair? M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cant? C, Cao B, Caraglia M, Caram?s B, Carchman EH, Cardenal-Mu?oz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382.Autophagy2021-02-08T00:00:002021Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.33665595Dow CT, Chan EDJournal of translational autoimmunityDow CT, Chan ED. What is the evidence that mycobacteria are associated with the pathogenesis of Sjogren's syndrome? J Transl Autoimmun. 2021; 4:100085.J Transl Autoimmun2021-02-05T00:00:002021What is the evidence that mycobacteria are associated with the pathogenesis of Sjogren's syndrome?33673937Chan ED, Sharma VMayo Clinic proceedingsChan ED, Sharma V. Does Hypoxia Itself Beget Worsening Hypoxemia in COVID-19? Mayo Clin Proc. 2021 03; 96(3):824-825.Mayo Clin Proc2021-01-20T00:00:002021Does Hypoxia Itself Beget Worsening Hypoxemia in COVID-19?Authorship 23895711Authorship 236984233713043Verma D, Chan ED, Ordway DJImmunological reviewsVerma D, Chan ED, Ordway DJ. The double-edged sword of Tregs in M tuberculosis, M avium, and M absessus infection. Immunol Rev. 2021 05; 301(1):48-61.Immunol Rev2021-03-12T00:00:002021The double-edged sword of Tregs in M tuberculosis, M avium, and M absessus infection.33855248Nelson ST, Robinson S, Rey K, Brown L, Jones N, Dawrs SN, Virdi R, Norton GJ, Epperson LE, Hasan NA, Chan ED, Strong M, Honda JRGeoHealthNelson ST, Robinson S, Rey K, Brown L, Jones N, Dawrs SN, Virdi R, Norton GJ, Epperson LE, Hasan NA, Chan ED, Strong M, Honda JR. Exposure Pathways of Nontuberculous Mycobacteria Through Soil, Streams, and Groundwater, Hawai'i, USA. Geohealth. 2021 Apr; 5(4):e2020GH000350.Geohealth2021-04-01T00:00:002021Exposure Pathways of Nontuberculous Mycobacteria Through Soil, Streams, and Groundwater, Hawai'i, USA.Authorship 2395001Authorship 2395642033879587Chan ED, Cota-Gomez A, Podell BmBioChan ED, Cota-Gomez A, Podell B. Adding Another Piece to the Puzzle of Why NTM Infections Are Relatively Uncommon despite Their Ubiquitous Nature. mBio. 2021 04 20; 12(2).mBio2021-04-20T00:00:002021Adding Another Piece to the Puzzle of Why NTM Infections Are Relatively Uncommon despite Their Ubiquitous Nature.33883256Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SDJournal for immunotherapy of cancerKnitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis. J Immunother Cancer. 2021 04; 9(4).J Immunother Cancer2021-04-01T00:00:002021Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.Authorship 177511Authorship 241497434076558Dempers L, Lane T, Moubry RM, Chan EDAnnals of the American Thoracic SocietyDempers L, Lane T, Moubry RM, Chan ED. Taking Extra Steps in Evaluating a Lung Nodule. Ann Am Thorac Soc. 2021 06; 18(6):1063-1065.Ann Am Thorac Soc2021-06-01T00:00:002021Taking Extra Steps in Evaluating a Lung Nodule.Authorship 246622934430367Chen J, Xie F, Zheng X, Li Y, Liu S, Ma KC, Goto T, M?ller T, Chan ED, Sun JTranslational lung cancer researchChen J, Xie F, Zheng X, Li Y, Liu S, Ma KC, Goto T, M?ller T, Chan ED, Sun J. Mobile 3-dimensional (3D) C-arm system-assisted transbronchial biopsy and ablation for ground-glass opacity pulmonary nodules: a case report. Transl Lung Cancer Res. 2021 Jul; 10(7):3312-3319.Transl Lung Cancer Res2021-07-01T00:00:002021Mobile 3-dimensional (3D) C-arm system-assisted transbronchial biopsy and ablation for ground-glass opacity pulmonary nodules: a case report.Authorship 2516817Authorship 252120534795948Tun MH, Borg B, Godfrey M, Hadley-Miller N, Chan EDJournal of thoracic diseaseTun MH, Borg B, Godfrey M, Hadley-Miller N, Chan ED. Respiratory manifestations of Marfan syndrome: a narrative review. J Thorac Dis. 2021 Oct; 13(10):6012-6025.J Thorac Dis2021-10-01T00:00:002021Respiratory manifestations of Marfan syndrome: a narrative review.34814845Johara FT, Benedetti A, Platt R, Menzies D, Viiklepp P, Schaaf S, Chan EBMC medical research methodologyJohara FT, Benedetti A, Platt R, Menzies D, Viiklepp P, Schaaf S, Chan E. Evaluating the performance of propensity score matching based approaches in individual patient data meta-analysis. BMC Med Res Methodol. 2021 11 23; 21(1):257.BMC Med Res Methodol2021-11-23T00:00:002021Evaluating the performance of propensity score matching based approaches in individual patient data meta-analysis.Authorship 255364834970090Choi S, Potts KJ, Althoff MD, Jimenez G, Bai X, Calhoun KM, Cool CD, Chan EDThe Yale journal of biology and medicineChoi S, Potts KJ, Althoff MD, Jimenez G, Bai X, Calhoun KM, Cool CD, Chan ED. Histopathologic Analysis of Surgically Resected Lungs of Patients with Non-tuberculous Mycobacterial Lung Disease: a Retrospective and Hypothesis-generating Study. Yale J Biol Med. 2021 12; 94(4):527-535.Yale J Biol Med2021-12-29T00:00:002021Histopathologic Analysis of Surgically Resected Lungs of Patients with Non-tuberculous Mycobacterial Lung Disease: a Retrospective and Hypothesis-generating Study.Authorship 256373535075444Ha DM, Prochazka AV, Bekelman DB, Stevens-Lapsley JE, Chan ED, Keith RLJNCI cancer spectrumHa DM, Prochazka AV, Bekelman DB, Stevens-Lapsley JE, Chan ED, Keith RL. Association of Leisure-Time Physical Activity With Health-Related Quality of Life Among US Lung Cancer Survivors. JNCI Cancer Spectr. 2021 02; 5(1).JNCI Cancer Spectr2021-01-23T00:00:002021Association of Leisure-Time Physical Activity With Health-Related Quality of Life Among US Lung Cancer Survivors.MichaelStrongMichael Strong39.74528180000000-104.837572700000008100Strong, MichaelAffiliate - NJHAuthorship 193813Authorship 257401335208878Dow CT, Greenblatt CL, Chan ED, Dow JFMicroorganismsDow CT, Greenblatt CL, Chan ED, Dow JF. Evaluation of BCG Vaccination and Plasma Amyloid: A Prospective, Pilot Study with Implications for Alzheimer's Disease. Microorganisms. 2022 Feb 12; 10(2).Microorganisms2022-02-12T00:00:002022Evaluation of BCG Vaccination and Plasma Amyloid: A Prospective, Pilot Study with Implications for Alzheimer's Disease.Authorship 2587051435338216Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan EDScientific reportsBai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 03 25; 12(1):5207.Sci Rep2022-03-25T00:00:002022Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.Authorship 25905814Authorship 2593459Authorship 259547235435715Parsons AW, Dawrs SN, Nelson ST, Norton GJ, Virdi R, Hasan NA, Epperson LE, Holst B, Chan ED, Leos-Barajas V, Reich BJ, Crooks JL, Strong M, Pacifici K, Honda JRApplied and environmental microbiologyParsons AW, Dawrs SN, Nelson ST, Norton GJ, Virdi R, Hasan NA, Epperson LE, Holst B, Chan ED, Leos-Barajas V, Reich BJ, Crooks JL, Strong M, Pacifici K, Honda JR. Soil Properties and Moisture Synergistically Influence Nontuberculous Mycobacterial Prevalence in Natural Environments of Hawai'i. Appl Environ Microbiol. 2022 05 10; 88(9):e0001822.Appl Environ Microbiol2022-04-18T00:00:002022Soil Properties and Moisture Synergistically Influence Nontuberculous Mycobacterial Prevalence in Natural Environments of Hawai'i.35440617Bai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan EDScientific reportsBai X, Buckle AM, Vladar EK, Janoff EN, Khare R, Ordway D, Beckham D, Fornis LB, Majluf-Cruz A, Fugit RV, Freed BM, Kim S, Sandhaus RA, Chan ED. Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. Sci Rep. 2022 Apr 19; 12(1):6466.Sci Rep2022-04-19T00:00:002022Author Correction: Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19.35476134Campbell JR, Chan ED, Falzon D, Trajman A, Keshavjee S, Leung CC, Miller AC, Monedero-Recuero I, Rodrigues DS, Seo H, Baghaei P, Udwadia Z, Viiklepp P, Bastos M, Menzies DClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaCampbell JR, Chan ED, Falzon D, Trajman A, Keshavjee S, Leung CC, Miller AC, Monedero-Recuero I, Rodrigues DS, Seo H, Baghaei P, Udwadia Z, Viiklepp P, Bastos M, Menzies D. Low Body Mass Index at Treatment Initiation and Rifampicin-Resistant Tuberculosis Treatment Outcomes: An Individual Participant Data Meta-Analysis. Clin Infect Dis. 2022 Apr 27.Clin Infect Dis2022-04-27T00:00:002022Low Body Mass Index at Treatment Initiation and Rifampicin-Resistant Tuberculosis Treatment Outcomes: An Individual Participant Data Meta-Analysis.Authorship 212944Authorship 264178235756056Byrd TF, Chan EDFrontiers in microbiologyByrd TF, Chan ED. Editorial: Mycobacterium abscessus; The Paradox of Low Pathogenicity and High Virulence. Front Microbiol. 2022; 13:943694.Front Microbiol2022-06-10T00:00:002022Editorial: Mycobacterium abscessus; The Paradox of Low Pathogenicity and High Virulence.Authorship 264403935799709Schenkel AR, Mitchell JD, Cool CD, Bai X, Groshong S, Koelsch T, Verma D, Ordway D, Chan EDImmune networkSchenkel AR, Mitchell JD, Cool CD, Bai X, Groshong S, Koelsch T, Verma D, Ordway D, Chan ED. Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection. Immune Netw. 2022 Jun; 22(3):e27.Immune Netw2022-04-11T00:00:002022Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection.Authorship 265335235889173Abdelaal HFM, Chan ED, Young L, Baldwin SL, Coler RNMicroorganismsAbdelaal HFM, Chan ED, Young L, Baldwin SL, Coler RN. Mycobacterium abscessus: It's Complex. Microorganisms. 2022 Jul 19; 10(7).Microorganisms2022-07-19T00:00:002022Mycobacterium abscessus: It's Complex.Authorship 232192Authorship 232881Authorship 27263819Authorship 27392610Authorship 2752324Authorship 2728511036684608Arguinchona LM, Zagona-Prizio C, Joyce ME, Chan ED, Maloney JPFrontiers in cardiovascular medicineArguinchona LM, Zagona-Prizio C, Joyce ME, Chan ED, Maloney JP. Microvascular significance of TGF-? axis activation in COVID-19. Front Cardiovasc Med. 2022; 9:1054690.Front Cardiovasc Med2023-01-06T00:00:002023Microvascular significance of TGF-? axis activation in COVID-19.36162872Bai X, Bai A, Tomasicchio M, Hagman JR, Buckle AM, Gupta A, Kadiyala V, Bevers S, Serban KA, Kim K, Feng Z, Spendier K, Hagen G, Fornis L, Griffith DE, Dzieciatkowska M, Sandhaus RA, Gerber AN, Chan EDJournal of immunology (Baltimore, Md. : 1950)Bai X, Bai A, Tomasicchio M, Hagman JR, Buckle AM, Gupta A, Kadiyala V, Bevers S, Serban KA, Kim K, Feng Z, Spendier K, Hagen G, Fornis L, Griffith DE, Dzieciatkowska M, Sandhaus RA, Gerber AN, Chan ED. a1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages. J Immunol. 2022 11 01; 209(9):1746-1759.J Immunol2022-09-26T00:00:002022a1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages.36388828Lu M, Chen W, Lei Z, Dai S, Hou C, Du S, Geake J, Bhurayanontachai R, Karamchand S, Chan ED, Jin Q, Li HAnnals of translational medicineLu M, Chen W, Lei Z, Dai S, Hou C, Du S, Geake J, Bhurayanontachai R, Karamchand S, Chan ED, Jin Q, Li H. Image-guided percutaneous biopsy and pathological diagnosis in atypical tuberculous spondylitis: a case series and clinical outcomes. Ann Transl Med. 2022 Oct; 10(20):1140.Ann Transl Med2022-10-01T00:00:002022Image-guided percutaneous biopsy and pathological diagnosis in atypical tuberculous spondylitis: a case series and clinical outcomes.36245600Youssefnia A, Pierre A, Hoder JM, MacDonald M, Shaffer MJB, Friedman J, Mehler PS, Bontempo A, da Silva FCN, Chan EDJournal of thoracic diseaseYoussefnia A, Pierre A, Hoder JM, MacDonald M, Shaffer MJB, Friedman J, Mehler PS, Bontempo A, da Silva FCN, Chan ED. Ancillary treatment of patients with lung disease due to non-tuberculous mycobacteria: a narrative review. J Thorac Dis. 2022 Sep; 14(9):3575-3597.J Thorac Dis2022-09-01T00:00:002022Ancillary treatment of patients with lung disease due to non-tuberculous mycobacteria: a narrative review.Authorship 277913836893126Peters J, Maselli DJ, Mangat M, Coalson JJ, Hinojosa C, Giavedoni L, Brown-Elliott BA, Chan E, Griffith DPloS onePeters J, Maselli DJ, Mangat M, Coalson JJ, Hinojosa C, Giavedoni L, Brown-Elliott BA, Chan E, Griffith D. A marmoset model for Mycobacterium avium complex pulmonary disease. PLoS One. 2023; 18(3):e0260563.PLoS One2023-03-09T00:00:002023A marmoset model for Mycobacterium avium complex pulmonary disease.Authorship 278293736923241Rockstrom M, Lutz R, Dickeson K, O'Rorke EV, Narita M, Amram O, Chan EDJournal of clinical tuberculosis and other mycobacterial diseasesRockstrom M, Lutz R, Dickeson K, O'Rorke EV, Narita M, Amram O, Chan ED. Fulminant pulmonary tuberculosis in a previously healthy young woman from the Marshall Islands: Potential risk factors. J Clin Tuberc Other Mycobact Dis. 2023 May; 31:100351.J Clin Tuberc Other Mycobact Dis2023-02-26T00:00:002023Fulminant pulmonary tuberculosis in a previously healthy young woman from the Marshall Islands: Potential risk factors.Authorship 281682337110254Dow CT, Lin NW, Chan EDMicroorganismsDow CT, Lin NW, Chan ED. Sarcoidosis, Mycobacterium paratuberculosis and Noncaseating Granulomas: Who Moved My Cheese. Microorganisms. 2023 Mar 24; 11(4).Microorganisms2023-03-24T00:00:002023Sarcoidosis, Mycobacterium paratuberculosis and Noncaseating Granulomas: Who Moved My Cheese.Authorship 261973Authorship 284466637294003Bai X, Schountz T, Buckle AM, Talbert JL, Sandhaus RA, Chan EDBiochemical Society transactionsBai X, Schountz T, Buckle AM, Talbert JL, Sandhaus RA, Chan ED. Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence. Biochem Soc Trans. 2023 06 28; 51(3):1361-1375.Biochem Soc Trans2023-06-28T00:00:002023Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence.Authorship 2853611137453489Dawrs SN, Virdi R, Islam MN, Hasan NA, Norton GJ, Crooks JL, Parr J, Heinz D, Cool CD, Belisle JT, Chan ED, Honda JRMicrobes and infectionDawrs SN, Virdi R, Islam MN, Hasan NA, Norton GJ, Crooks JL, Parr J, Heinz D, Cool CD, Belisle JT, Chan ED, Honda JR. Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model. Microbes Infect. 2023 Nov-Dec; 25(8):105184.Microbes Infect2023-07-14T00:00:002023Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model.Authorship 266948Authorship 272310true1Distinguished ProfessorDistinguished Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Affiliate - NJHAffiliate - NJHAuthorship 2882021037703253Hendrix J, Epperson LE, Tong EI, Chan YL, Hasan NA, Dawrs SN, Norton GJ, Virdi R, Crooks JL, Chan ED, Honda JR, Strong MPloS oneHendrix J, Epperson LE, Tong EI, Chan YL, Hasan NA, Dawrs SN, Norton GJ, Virdi R, Crooks JL, Chan ED, Honda JR, Strong M. Complete genome assembly of Hawai'i environmental nontuberculous mycobacteria reveals unexpected co-isolation with methylobacteria. PLoS One. 2023; 18(9):e0291072.PLoS One2023-09-13T00:00:002023Complete genome assembly of Hawai'i environmental nontuberculous mycobacteria reveals unexpected co-isolation with methylobacteria.true1Asst ProfessorAsst Professortrue1Assoc Professor-ResearchAssoc Professor-Researchtrue1Affiliate - NJHAffiliate - NJHtrue1Asst ProfessorAsst Professortrue1Asst Professor-ResearchAsst Professor-Researchtrue1Principal InvestigatorPrincipal Investigatortrue1Post-Doctoral FellowPost-Doctoral Fellowtrue1InstructorInstructortrue1Affiliate - NJHAffiliate - NJHAuthorship 2949861637965256Bai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, Griffith DE, Li L, Whittel N, Gadwa J, Ohanjanyan T, Eggleston MJ, Galvan M, Freed BM, Ordway D, Chan EDFrontiers in cellular and infection microbiologyBai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, Griffith DE, Li L, Whittel N, Gadwa J, Ohanjanyan T, Eggleston MJ, Galvan M, Freed BM, Ordway D, Chan ED. Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis. Front Cell Infect Microbiol. 2023; 13:1216492.Front Cell Infect Microbiol2023-10-26T00:00:002023Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis.Authorship 2977251338161597Dawrs SN, Virdi R, Norton GJ, Elias T, Hasan NA, Robinson S, Matriz J, Epperson LE, Glickman CM, Beagle S, Crooks JL, Nelson ST, Chan ED, Damby DE, Strong M, Honda JRGeoHealthDawrs SN, Virdi R, Norton GJ, Elias T, Hasan NA, Robinson S, Matriz J, Epperson LE, Glickman CM, Beagle S, Crooks JL, Nelson ST, Chan ED, Damby DE, Strong M, Honda JR. Hawaiian Volcanic Ash, an Airborne Fomite for Nontuberculous Mycobacteria. Geohealth. 2024 Jan; 8(1):e2023GH000889.Geohealth2023-12-30T00:00:002023Hawaiian Volcanic Ash, an Airborne Fomite for Nontuberculous Mycobacteria.2027-06-30NIHCHAN, EDWARD D2023-07-01Establishing the Therapeutic Efficacy of Alpha-1-Antitrypsin and Enoxaparin Against COVID-19I01BX005651Principal InvestigatorAuthorship 298750138237158Chan EDAmerican journal of respiratory and critical care medicineChan ED. Identification of AAT-Deficient Subjects with Normal Spirometry Who May Benefit from AAT Replacement. Am J Respir Crit Care Med. 2024 Jan 18.Am J Respir Crit Care Med2024-01-18T00:00:002024Identification of AAT-Deficient Subjects with Normal Spirometry Who May Benefit from AAT Replacement.Authorship 330911Authorship 34712Authorship 106383524297127Chan MM, Chan MM, Mengshol JA, Fish DN, Chan EDChestChan MM, Chan MM, Mengshol JA, Fish DN, Chan ED. Octreotide: a drug often used in the critical care setting but not well understood. Chest. 2013 Dec; 144(6):1937-1945.Chest2013-12-01T00:00:002013Octreotide: a drug often used in the critical care setting but not well understood.Authorship 366837Authorship 377081Authorship 410745Authorship 411575Authorship 444366Authorship 106948324336756Czaja CA, Merkel PA, Chan ED, Lenz LL, Wolf ML, Alam R, Frankel SK, Fischer A, Gogate S, Perez-Velez CM, Knight VClinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaCzaja CA, Merkel PA, Chan ED, Lenz LL, Wolf ML, Alam R, Frankel SK, Fischer A, Gogate S, Perez-Velez CM, Knight V. Rituximab as successful adjunct treatment in a patient with disseminated nontuberculous mycobacterial infection due to acquired anti-interferon-? autoantibody. Clin Infect Dis. 2014 Mar; 58(6):e115-8.Clin Infect Dis2013-12-11T00:00:002013Rituximab as successful adjunct treatment in a patient with disseminated nontuberculous mycobacterial infection due to acquired anti-interferon-? autoantibody.Authorship 44813Authorship 4490318Authorship 46302Authorship 464398Authorship 466735Authorship 498385Authorship 498558Authorship 515312Authorship 522055Authorship 527962Authorship 537729YaelAschnerYael Aschner39.74515960000000-104.840628000000008790Aschner, YaelAsst ProfessorAuthorship 540676Authorship 112122424821067Honda JR, Connick E, MaWhinney S, Chan ED, Flores SCJournal of medical microbiologyHonda JR, Connick E, MaWhinney S, Chan ED, Flores SC. Plasma LL-37 correlates with vitamin D and is reduced in human immunodeficiency virus-1 infected individuals not receiving antiretroviral therapy. J Med Microbiol. 2014 Jul; 63(Pt 7):997-1003.J Med Microbiol2014-05-12T00:00:002014Plasma LL-37 correlates with vitamin D and is reduced in human immunodeficiency virus-1 infected individuals not receiving antiretroviral therapy.Authorship 548062Authorship 549196Authorship 562993Authorship 576255Authorship 579733Authorship 584408Authorship 593062Authorship 606096Authorship 609433Authorship 624241Authorship 642264Authorship 113476224736105Wu GC, Chan ED, Chou YC, Yu CY, Hsieh TY, Hsieh CB, Chian CF, Ke FC, Dai YL, Su WLAnti-cancer drugsWu GC, Chan ED, Chou YC, Yu CY, Hsieh TY, Hsieh CB, Chian CF, Ke FC, Dai YL, Su WL. Risk factors for the development of pulmonary oil embolism after transcatheter arterial chemoembolization of hepatic tumors. Anticancer Drugs. 2014 Sep; 25(8):976-81.Anticancer Drugs2014-09-01T00:00:002014Risk factors for the development of pulmonary oil embolism after transcatheter arterial chemoembolization of hepatic tumors.Authorship 653126Authorship 673321Authorship 684904Authorship 691921Authorship 6962319Authorship 696918Authorship 705641Authorship 70621Authorship 706302Authorship 71865325305002Chan ED, Kinney WH, Honda JR, Bishwakarma R, Gangavelli A, Mya J, Bai X, Ordway DJTuberculosis (Edinburgh, Scotland)Chan ED, Kinney WH, Honda JR, Bishwakarma R, Gangavelli A, Mya J, Bai X, Ordway DJ. Tobacco exposure and susceptibility to tuberculosis: is there a smoking gun? Tuberculosis (Edinb). 2014 Dec; 94(6):544-50.Tuberculosis (Edinb)2014-09-28T00:00:002014Tobacco exposure and susceptibility to tuberculosis: is there a smoking gun?25155501Kim E, Kinney WH, Ovrutsky AR, Vo D, Bai X, Honda JR, Marx G, Peck E, Lindberg L, Falkinham JO, May RM, Chan EDFEMS microbiology lettersKim E, Kinney WH, Ovrutsky AR, Vo D, Bai X, Honda JR, Marx G, Peck E, Lindberg L, Falkinham JO, May RM, Chan ED. A surface with a biomimetic micropattern reduces colonization of Mycobacterium abscessus. FEMS Microbiol Lett. 2014 Nov; 360(1):17-22.FEMS Microbiol Lett2014-09-09T00:00:002014A surface with a biomimetic micropattern reduces colonization of Mycobacterium abscessus.Authorship 738194Authorship 753231Authorship 758852Authorship 760131Authorship 761434Authorship 76767Authorship 11760612Authorship 793393Authorship 7935110