 Connection
Kathryn Horwitz to Tumor Cells, Cultured
This is a "connection" page, showing publications Kathryn Horwitz has written about Tumor Cells, Cultured.
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Connection Strength |
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0.789 |
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Jacobsen BM, Jambal P, Schittone SA, Horwitz KB. ALU repeats in promoters are position-dependent co-response elements (coRE) that enhance or repress transcription by dimeric and monomeric progesterone receptors. Mol Endocrinol. 2009 Jul; 23(7):989-1000.
Score: 0.069
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Tung L, Abdel-Hafiz H, Shen T, Harvell DM, Nitao LK, Richer JK, Sartorius CA, Takimoto GS, Horwitz KB. Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B. Mol Endocrinol. 2006 Nov; 20(11):2656-70.
Score: 0.057
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Sartorius CA, Shen T, Horwitz KB. Progesterone receptors A and B differentially affect the growth of estrogen-dependent human breast tumor xenografts. Breast Cancer Res Treat. 2003 Jun; 79(3):287-99.
Score: 0.046
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Jacobsen BM, Richer JK, Schittone SA, Horwitz KB. New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation. J Biol Chem. 2002 Aug 02; 277(31):27793-800.
Score: 0.043
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Richer JK, Jacobsen BM, Manning NG, Abel MG, Wolf DM, Horwitz KB. Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells. J Biol Chem. 2002 Feb 15; 277(7):5209-18.
Score: 0.042
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Owen GI, Richer JK, Tung L, Takimoto G, Horwitz KB. Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300. J Biol Chem. 1998 Apr 24; 273(17):10696-701.
Score: 0.032
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Richer JK, Lange CA, Wierman AM, Brooks KM, Tung L, Takimoto GS, Horwitz KB. Progesterone receptor variants found in breast cells repress transcription by wild-type receptors. Breast Cancer Res Treat. 1998 Apr; 48(3):231-41.
Score: 0.032
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Groshong SD, Owen GI, Grimison B, Schauer IE, Todd MC, Langan TA, Sclafani RA, Lange CA, Horwitz KB. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Mol Endocrinol. 1997 Oct; 11(11):1593-607.
Score: 0.031
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Miller MM, James RA, Richer JK, Gordon DF, Wood WM, Horwitz KB. Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. J Clin Endocrinol Metab. 1997 Sep; 82(9):2956-61.
Score: 0.031
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Horwitz KB, Tung L, Takimoto GS. Novel mechanisms of antiprogestin action. J Steroid Biochem Mol Biol. 1995 Jun; 53(1-6):9-17.
Score: 0.027
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Horwitz KB, Sartorius CA, Hovland AR, Jackson TA, Groshong SD, Tung L, Takimoto GS. Surprises with antiprogestins: novel mechanisms of progesterone receptor action. Ciba Found Symp. 1995; 191:235-49; discussion 250-3.
Score: 0.026
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Sartorius CA, Groshong SD, Miller LA, Powell RL, Tung L, Takimoto GS, Horwitz KB. New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP. Cancer Res. 1994 Jul 15; 54(14):3868-77.
Score: 0.025
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Horwitz KB. Hormone-resistant breast cancer or "feeding the hand that bites you". Prog Clin Biol Res. 1994; 387:29-45.
Score: 0.024
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Horwitz KB. Can hormone "resistant" breast cancer cells be inappropriately stimulated by tamoxifen? Ann N Y Acad Sci. 1993 Jun 11; 684:63-74.
Score: 0.023
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Sartorius CA, Tung L, Takimoto GS, Horwitz KB. Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP. J Biol Chem. 1993 May 05; 268(13):9262-6.
Score: 0.023
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Horwitz KB. Mechanisms of hormone resistance in breast cancer. Breast Cancer Res Treat. 1993; 26(2):119-30.
Score: 0.022
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Horwitz KB. The molecular biology of RU486. Is there a role for antiprogestins in the treatment of breast cancer? Endocr Rev. 1992 May; 13(2):146-63.
Score: 0.021
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Leslie KK, Tasset DM, Horwitz KB. Functional analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells. Am J Obstet Gynecol. 1992 Apr; 166(4):1053-61.
Score: 0.021
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Wei LL, Gonzalez-Aller C, Wood WM, Miller LA, Horwitz KB. 5'-Heterogeneity in human progesterone receptor transcripts predicts a new amino-terminal truncated "C"-receptor and unique A-receptor messages. Mol Endocrinol. 1990 Dec; 4(12):1833-40.
Score: 0.019
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Graham ML, Krett NL, Miller LA, Leslie KK, Gordon DF, Wood WM, Wei LL, Horwitz KB. T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance. Cancer Res. 1990 Oct 01; 50(19):6208-17.
Score: 0.019
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Graham ML, Bunn PA, Jewett PB, Gonzalez-Aller C, Horwitz KB. Simultaneous measurement of progesterone receptors and DNA indices by flow cytometry: characterization of an assay in breast cancer cell lines. Cancer Res. 1989 Jul 15; 49(14):3934-42.
Score: 0.018
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Sheridan PL, Francis MD, Horwitz KB. Synthesis of human progesterone receptors in T47D cells. Nascent A- and B-receptors are active without a phosphorylation-dependent post-translational maturation step. J Biol Chem. 1989 Apr 25; 264(12):7054-8.
Score: 0.017
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Sheridan PL, Krett NL, Gordon JA, Horwitz KB. Human progesterone receptor transformation and nuclear down-regulation are independent of phosphorylation. Mol Endocrinol. 1988 Dec; 2(12):1329-42.
Score: 0.017
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Horwitz KB. Purification, monoclonal antibody production and structural analyses of human progesterone receptors. J Steroid Biochem. 1988 Oct; 31(4B):573-8.
Score: 0.017
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Lange CA, Sartorius CA, Abdel-Hafiz H, Spillman MA, Horwitz KB, Jacobsen BM. Progesterone receptor action: translating studies in breast cancer models to clinical insights. Adv Exp Med Biol. 2008; 630:94-111.
Score: 0.016
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Wu J, Richer J, Horwitz KB, Hyder SM. Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B. Cancer Res. 2004 Mar 15; 64(6):2238-44.
Score: 0.012
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Qiu M, Olsen A, Faivre E, Horwitz KB, Lange CA. Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors. Mol Endocrinol. 2003 Apr; 17(4):628-42.
Score: 0.011
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Shen T, Horwitz KB, Lange CA. Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. Mol Cell Biol. 2001 Sep; 21(18):6122-31.
Score: 0.010
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Pahl PM, Horwitz MA, Horwitz KB, Horwitz LD. Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells. Breast Cancer Res Treat. 2001 Sep; 69(1):69-79.
Score: 0.010
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Kinyamu HK, Fryer CJ, Horwitz KB, Archer TK. The mouse mammary tumor virus promoter adopts distinct chromatin structures in human breast cancer cells with and without glucocorticoid receptor. J Biol Chem. 2000 Jun 30; 275(26):20061-8.
Score: 0.009
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Kumar NS, Richer J, Owen G, Litman E, Horwitz KB, Leslie KK. Selective down-regulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: implications for unopposed estrogen action. Cancer Res. 1998 May 01; 58(9):1860-5.
Score: 0.008
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Leslie KK, Kumar NS, Richer J, Owen G, Takimoto G, Horwitz KB, Lange C. Differential expression of the A and B isoforms of progesterone receptor in human endometrial cancer cells. Only progesterone receptor B is induced by estrogen and associated with strong transcriptional activation. Ann N Y Acad Sci. 1997 Sep 26; 828:17-26.
Score: 0.008
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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