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Connection

Kurt Stenmark to Muscle, Smooth, Vascular

This is a "connection" page, showing publications Kurt Stenmark has written about Muscle, Smooth, Vascular.

 
Connection Strength
  
 
 
5.504
  
  1. Hu CJ, Poth JM, Zhang H, Flockton A, Laux A, Kumar S, McKeon B, Mouradian G, Li M, Riddle S, Pugliese SC, Brown RD, Wallace EM, Graham BB, Frid MG, Stenmark KR. Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension. Eur Respir J. 2019 12; 54(6).
    View in: PubMed
    Score: 0.528
  2. Stenmark KR, Frid MG, Graham BB, Tuder RM. Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension. Cardiovasc Res. 2018 03 15; 114(4):551-564.
    View in: PubMed
    Score: 0.468
  3. Yeager ME, Belchenko DD, Nguyen CM, Colvin KL, Ivy DD, Stenmark KR. Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 2012 Jan; 46(1):14-22.
    View in: PubMed
    Score: 0.304
  4. Stevens T, Phan S, Frid MG, Alvarez D, Herzog E, Stenmark KR. Lung vascular cell heterogeneity: endothelium, smooth muscle, and fibroblasts. Proc Am Thorac Soc. 2008 Sep 15; 5(7):783-91.
    View in: PubMed
    Score: 0.242
  5. Stiebellehner L, Frid MG, Reeves JT, Low RB, Gnanasekharan M, Stenmark KR. Bovine distal pulmonary arterial media is composed of a uniform population of well-differentiated smooth muscle cells with low proliferative capabilities. Am J Physiol Lung Cell Mol Physiol. 2003 Oct; 285(4):L819-28.
    View in: PubMed
    Score: 0.169
  6. Frid MG, Kale VA, Stenmark KR. Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis. Circ Res. 2002 Jun 14; 90(11):1189-96.
    View in: PubMed
    Score: 0.157
  7. Das M, Bouchey DM, Moore MJ, Hopkins DC, Nemenoff RA, Stenmark KR. Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases. J Biol Chem. 2001 May 11; 276(19):15631-40.
    View in: PubMed
    Score: 0.143
  8. Weiser-Evans MC, Schwartz PE, Grieshaber NA, Quinn BE, Grieshaber SS, Belknap JK, Mourani PM, Majack RA, Stenmark KR. Novel embryonic genes are preferentially expressed by autonomously replicating rat embryonic and neointimal smooth muscle cells. Circ Res. 2000 Sep 29; 87(7):608-15.
    View in: PubMed
    Score: 0.139
  9. Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Sci Rep. 2020 01 15; 10(1):413.
    View in: PubMed
    Score: 0.133
  10. Weiser-Evans MC, Quinn BE, Burkard MR, Stenmark KR. Transient reexpression of an embryonic autonomous growth phenotype by adult carotid artery smooth muscle cells after vascular injury. J Cell Physiol. 2000 Jan; 182(1):12-23.
    View in: PubMed
    Score: 0.132
  11. Durmowicz AG, Stenmark KR. Mechanisms of structural remodeling in chronic pulmonary hypertension. Pediatr Rev. 1999 Nov; 20(11):e91-e102.
    View in: PubMed
    Score: 0.131
  12. Humbert M, Guignabert C, Bonnet S, Dorfmüller P, Klinger JR, Nicolls MR, Olschewski AJ, Pullamsetti SS, Schermuly RT, Stenmark KR, Rabinovitch M. Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. Eur Respir J. 2019 01; 53(1).
    View in: PubMed
    Score: 0.124
  13. Stenmark KR, Frid M, Nemenoff R, Dempsey EC, Das M. Hypoxia induces cell-specific changes in gene expression in vascular wall cells: implications for pulmonary hypertension. Adv Exp Med Biol. 1999; 474:231-58.
    View in: PubMed
    Score: 0.124
  14. Dempsey EC, Das M, Frid MG, Xu Y, Stenmark KR. Hypoxic growth of bovine pulmonary artery smooth muscle cells: dependence on synergy, heterogeneity, and injury-induced phenotypic change. Chest. 1998 Jul; 114(1 Suppl):29S-30S.
    View in: PubMed
    Score: 0.119
  15. Stenmark KR, Frid MG. Smooth muscle cell heterogeneity: role of specific smooth muscle cell subpopulations in pulmonary vascular disease. Chest. 1998 Jul; 114(1 Suppl):82S-90S.
    View in: PubMed
    Score: 0.119
  16. Ding Y, Xu X, Sharma S, Floren M, Stenmark K, Bryant SJ, Neu CP, Tan W. Biomimetic soft fibrous hydrogels for contractile and pharmacologically responsive smooth muscle. Acta Biomater. 2018 07 01; 74:121-130.
    View in: PubMed
    Score: 0.118
  17. Frid MG, Aldashev AA, Dempsey EC, Stenmark KR. Smooth muscle cells isolated from discrete compartments of the mature vascular media exhibit unique phenotypes and distinct growth capabilities. Circ Res. 1997 Dec; 81(6):940-52.
    View in: PubMed
    Score: 0.115
  18. Frid MG, Dempsey EC, Durmowicz AG, Stenmark KR. Smooth muscle cell heterogeneity in pulmonary and systemic vessels. Importance in vascular disease. Arterioscler Thromb Vasc Biol. 1997 Jul; 17(7):1203-9.
    View in: PubMed
    Score: 0.111
  19. Dempsey EC, Frid MG, Aldashev AA, Das M, Stenmark KR. Heterogeneity in the proliferative response of bovine pulmonary artery smooth muscle cells to mitogens and hypoxia: importance of protein kinase C. Can J Physiol Pharmacol. 1997 Jul; 75(7):936-44.
    View in: PubMed
    Score: 0.111
  20. Madhavan K, Frid MG, Hunter K, Shandas R, Stenmark KR, Park D. Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting. J Biomed Mater Res B Appl Biomater. 2018 Jan; 106(1):278-290.
    View in: PubMed
    Score: 0.108
  21. Dempsey EC, Das M, Frid MG, Stenmark KR. Unique growth properties of neonatal pulmonary vascular cells: importance of time- and site-specific responses, cell-cell interaction, and synergy. J Perinatol. 1996 Mar-Apr; 16(2 Pt 2 Su):S2-11.
    View in: PubMed
    Score: 0.101
  22. Durmowicz AG, Stenmark KR. Alterations in extracellular matrix protein expression in neonatal pulmonary hypertension: implications for vascular function. J Perinatol. 1996 Mar-Apr; 16(2 Pt 2 Su):S11-8.
    View in: PubMed
    Score: 0.101
  23. Deng L, Blanco FJ, Stevens H, Lu R, Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, Stenmark K, White K, Seto AG, Morrell NW, Bradshaw AC, MacLean MR, Baker AH. MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension. Circ Res. 2015 Oct 23; 117(10):870-883.
    View in: PubMed
    Score: 0.098
  24. Zhao L, Oliver E, Maratou K, Atanur SS, Dubois OD, Cotroneo E, Chen CN, Wang L, Arce C, Chabosseau PL, Ponsa-Cobas J, Frid MG, Moyon B, Webster Z, Aldashev A, Ferrer J, Rutter GA, Stenmark KR, Aitman TJ, Wilkins MR. The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia. Nature. 2015 Aug 20; 524(7565):356-60.
    View in: PubMed
    Score: 0.098
  25. Wohrley JD, Frid MG, Moiseeva EP, Orton EC, Belknap JK, Stenmark KR. Hypoxia selectively induces proliferation in a specific subpopulation of smooth muscle cells in the bovine neonatal pulmonary arterial media. J Clin Invest. 1995 Jul; 96(1):273-81.
    View in: PubMed
    Score: 0.097
  26. Frid MG, Moiseeva EP, Stenmark KR. Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo. Circ Res. 1994 Oct; 75(4):669-81.
    View in: PubMed
    Score: 0.092
  27. Dempsey EC, Badesch DB, Dobyns EL, Stenmark KR. Enhanced growth capacity of neonatal pulmonary artery smooth muscle cells in vitro: dependence on cell size, time from birth, insulin-like growth factor I, and auto-activation of protein kinase C. J Cell Physiol. 1994 Sep; 160(3):469-81.
    View in: PubMed
    Score: 0.091
  28. Tuder RM, Archer SL, Dorfmüller P, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D4-12.
    View in: PubMed
    Score: 0.087
  29. Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism. Circ Res. 2012 Mar 02; 110(5):739-48.
    View in: PubMed
    Score: 0.076
  30. Durmowicz AG, Badesch DB, Parks WC, Mecham RP, Stenmark KR. Hypoxia-induced inhibition of tropoelastin synthesis by neonatal calf pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 1991 Nov; 5(5):464-9.
    View in: PubMed
    Score: 0.075
  31. Li M, Stenmark KR, Shandas R, Tan W. Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. J Vasc Res. 2009; 46(6):561-71.
    View in: PubMed
    Score: 0.064
  32. Badesch DB, Lee PD, Parks WC, Stenmark KR. Insulin-like growth factor I stimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells. Biochem Biophys Res Commun. 1989 Apr 14; 160(1):382-7.
    View in: PubMed
    Score: 0.063
  33. Stenmark KR, Orton EC, Reeves JT, Voelkel NF, Crouch EC, Parks WC, Mecham RP. Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell. Chest. 1988 Mar; 93(3 Suppl):127S-133S.
    View in: PubMed
    Score: 0.058
  34. Wenzlau JM, Garl PJ, Simpson P, Stenmark KR, West J, Artinger KB, Nemenoff RA, Weiser-Evans MC. Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development. Circ Res. 2006 Mar 31; 98(6):846-55.
    View in: PubMed
    Score: 0.051
  35. Frid MG, Brunetti JA, Burke DL, Carpenter TC, Davie NJ, Reeves JT, Roedersheimer MT, van Rooijen N, Stenmark KR. Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage. Am J Pathol. 2006 Feb; 168(2):659-69.
    View in: PubMed
    Score: 0.050
  36. Lewis CV, Nguyen TN, Porfilio TE, Burciaga SD, Posey JN, Jordan M, Colon Hidalgo D, Stenmark KR, Mickael C, Sul C, Oberley-Deegan RE, Delaney C, Nozik ES. Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia. Am J Physiol Lung Cell Mol Physiol. 2025 Jun 01; 328(6):L885-L900.
    View in: PubMed
    Score: 0.048
  37. Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation. 2004 Mar 16; 109(10):1299-306.
    View in: PubMed
    Score: 0.044
  38. Short M, Nemenoff RA, Zawada WM, Stenmark KR, Das M. Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C416-25.
    View in: PubMed
    Score: 0.043
  39. Tock J, Van Putten V, Stenmark KR, Nemenoff RA. Induction of SM-alpha-actin expression by mechanical strain in adult vascular smooth muscle cells is mediated through activation of JNK and p38 MAP kinase. Biochem Biophys Res Commun. 2003 Feb 21; 301(4):1116-21.
    View in: PubMed
    Score: 0.041
  40. Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46132-41.
    View in: PubMed
    Score: 0.037
  41. Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold J, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, Gupte SA. Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation. Am J Physiol Lung Cell Mol Physiol. 2020 04 01; 318(4):L773-L786.
    View in: PubMed
    Score: 0.034
  42. Frid MG, Aldashev AA, Nemenoff RA, Higashito R, Westcott JY, Stenmark KR. Subendothelial cells from normal bovine arteries exhibit autonomous growth and constitutively activated intracellular signaling. Arterioscler Thromb Vasc Biol. 1999 Dec; 19(12):2884-93.
    View in: PubMed
    Score: 0.033
  43. Guldemeester A, Stenmark KR, Brough GH, Stevens T. Mechanisms regulating cAMP-mediated growth of bovine neonatal pulmonary artery smooth muscle cells. Am J Physiol. 1999 06; 276(6):L1010-7.
    View in: PubMed
    Score: 0.032
  44. Belknap JK, Weiser-Evans MC, Grieshaber SS, Majack RA, Stenmark KR. Relationship between perlecan and tropoelastin gene expression and cell replication in the developing rat pulmonary vasculature. Am J Respir Cell Mol Biol. 1999 Jan; 20(1):24-34.
    View in: PubMed
    Score: 0.031
  45. Guldemeester HA, Stenmark KR, Brough G, Tuder RM, Stevens T. Role of adenylyl cyclase in proliferation of neonatal pulmonary artery smooth muscle cells. Chest. 1998 Jul; 114(1 Suppl):38S-39S.
    View in: PubMed
    Score: 0.030
  46. Rashid J, Alobaida A, Al-Hilal TA, Hammouda S, McMurtry IF, Nozik-Grayck E, Stenmark KR, Ahsan F. Repurposing rosiglitazone, a PPAR-? agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH. J Control Release. 2018 06 28; 280:113-123.
    View in: PubMed
    Score: 0.029
  47. Xu Y, Stenmark KR, Das M, Walchak SJ, Ruff LJ, Dempsey EC. Pulmonary artery smooth muscle cells from chronically hypoxic neonatal calves retain fetal-like and acquire new growth properties. Am J Physiol. 1997 Jul; 273(1 Pt 1):L234-45.
    View in: PubMed
    Score: 0.028
  48. Rashid J, Patel B, Nozik-Grayck E, McMurtry IF, Stenmark KR, Ahsan F. Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH). J Control Release. 2017 03 28; 250:96-106.
    View in: PubMed
    Score: 0.027
  49. Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik-Grayck E, Ferguson SK, Hassell K, Nuss R, Stenmark K, Buehler P, Irwin DC. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS One. 2017; 12(2):e0171219.
    View in: PubMed
    Score: 0.027
  50. Morrell NW, Grieshaber SS, Danilov SM, Majack RA, Stenmark KR. Developmental regulation of angiotensin converting enzyme and angiotensin type 1 receptor in the rat pulmonary circulation. Am J Respir Cell Mol Biol. 1996 Jun; 14(6):526-37.
    View in: PubMed
    Score: 0.026
  51. Durmowicz AG, Frid MG, Wohrley JD, Stenmark KR. Expression and localization of tropoelastin mRNA in the developing bovine pulmonary artery is dependent on vascular cell phenotype. Am J Respir Cell Mol Biol. 1996 Jun; 14(6):569-76.
    View in: PubMed
    Score: 0.026
  52. Nozik-Grayck E, Woods C, Stearman RS, Venkataraman S, Ferguson BS, Swain K, Bowler RP, Geraci MW, Ihida-Stansbury K, Stenmark KR, McKinsey TA, Domann FE. Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2016 07 01; 311(1):L124-34.
    View in: PubMed
    Score: 0.026
  53. Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension. Circulation. 2014 Apr 29; 129(17):1770-80.
    View in: PubMed
    Score: 0.022
  54. Zhao L, Chen CN, Hajji N, Oliver E, Cotroneo E, Wharton J, Wang D, Li M, McKinsey TA, Stenmark KR, Wilkins MR. Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid. Circulation. 2012 Jul 24; 126(4):455-67.
    View in: PubMed
    Score: 0.020
  55. Mecham RP, Stenmark KR, Parks WC. Connective tissue production by vascular smooth muscle in development and disease. Chest. 1991 Mar; 99(3 Suppl):43S-47S.
    View in: PubMed
    Score: 0.018
  56. Dempsey EC, Stenmark KR, McMurtry IF, O'Brien RF, Voelkel NF, Badesch DB. Insulin-like growth factor I and protein kinase C activation stimulate pulmonary artery smooth muscle cell proliferation through separate but synergistic pathways. J Cell Physiol. 1990 Jul; 144(1):159-65.
    View in: PubMed
    Score: 0.017
  57. Badesch DB, Orton EC, Zapp LM, Westcott JY, Hester J, Voelkel NF, Stenmark KR. Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension. Am J Respir Cell Mol Biol. 1989 Dec; 1(6):489-98.
    View in: PubMed
    Score: 0.016
  58. Crouch EC, Parks WC, Rosenbaum JL, Chang D, Whitehouse L, Wu LJ, Stenmark KR, Orton EC, Mecham RP. Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension. Am Rev Respir Dis. 1989 Oct; 140(4):1045-51.
    View in: PubMed
    Score: 0.016
  59. Mecham RP, Whitehouse LA, Wrenn DS, Parks WC, Griffin GL, Senior RM, Crouch EC, Stenmark KR, Voelkel NF. Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension. Science. 1987 Jul 24; 237(4813):423-6.
    View in: PubMed
    Score: 0.014
  60. Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol. 2004 Jun 16; 43(12 Suppl S):13S-24S.
    View in: PubMed
    Score: 0.011
  61. Yu AY, Frid MG, Shimoda LA, Wiener CM, Stenmark K, Semenza GL. Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung. Am J Physiol. 1998 10; 275(4):L818-26.
    View in: PubMed
    Score: 0.008
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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