 Connection
Jed Lampe to Cytochrome P-450 Enzyme System
This is a "connection" page, showing publications Jed Lampe has written about Cytochrome P-450 Enzyme System.
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Connection Strength |
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2.775 |
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Tooker BC, Kandel SE, Work HM, Lampe JN. Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE. J Biol Chem. 2022 03; 298(3):101629.
Score: 0.754
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Kandel SE, Lampe JN. Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity. Chem Res Toxicol. 2014 Sep 15; 27(9):1474-86.
Score: 0.451
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Lampe JN, Brandman R, Sivaramakrishnan S, de Montellano PRO. Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates. J Biol Chem. 2010 Mar 26; 285(13):9594-9603.
Score: 0.328
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Lampe JN, Floor SN, Gross JD, Nishida CR, Jiang Y, Trnka MJ, Ortiz de Montellano PR. Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine. J Am Chem Soc. 2008 Dec 03; 130(48):16168-9.
Score: 0.303
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Lampe JN, Fernandez C, Nath A, Atkins WM. Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4. Biochemistry. 2008 Jan 15; 47(2):509-16.
Score: 0.284
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Lampe JN, Atkins WM. Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4. Biochemistry. 2006 Oct 10; 45(40):12204-15.
Score: 0.261
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Basudhar D, Madrona Y, Kandel S, Lampe JN, Nishida CR, de Montellano PR. Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography. J Biol Chem. 2015 Apr 17; 290(16):10000-17.
Score: 0.116
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Brandman R, Lampe JN, Brandman Y, de Montellano PR. Active-site residues move independently from the rest of the protein in a 200 ns molecular dynamics simulation of cytochrome P450 CYP119. Arch Biochem Biophys. 2011 May 15; 509(2):127-32.
Score: 0.089
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Wen B, Lampe JN, Roberts AG, Atkins WM, David Rodrigues A, Nelson SD. Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase. Arch Biochem Biophys. 2006 Oct 01; 454(1):42-54.
Score: 0.065
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Roberts AG, D?az MD, Lampe JN, Shireman LM, Grinstead JS, Dabrowski MJ, Pearson JT, Bowman MK, Atkins WM, Campbell AP. NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity. Biochemistry. 2006 Feb 14; 45(6):1673-84.
Score: 0.062
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Wen B, Doneanu CE, Lampe JN, Roberts AG, Atkins WM, Nelson SD. Probing the CYP3A4 active site by cysteine scanning mutagenesis and photoaffinity labeling. Arch Biochem Biophys. 2005 Dec 15; 444(2):100-11.
Score: 0.061
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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