 Connection
Leslie Berg to Protein-Tyrosine Kinases
This is a "connection" page, showing publications Leslie Berg has written about Protein-Tyrosine Kinases.
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Connection Strength |
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10.487 |
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Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
Score: 0.603
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Conley JM, Gallagher MP, Rao A, Berg LJ. Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength. J Immunol. 2020 07 15; 205(2):335-345.
Score: 0.553
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Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8+ T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 2020 02 07; 4(2):57-71.
Score: 0.541
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Cho HS, Reboldi A, Hall JA, Berg LJ. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine. Nat Commun. 2019 02 15; 10(1):784.
Score: 0.505
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Andreotti AH, Joseph RE, Conley JM, Iwasa J, Berg LJ. Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. Annu Rev Immunol. 2018 04 26; 36:549-578.
Score: 0.478
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Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ. A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression. J Immunol. 2015 Nov 15; 195(10):4822-31.
Score: 0.401
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Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ. Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways. J Immunol. 2014 Jul 15; 193(2):688-99.
Score: 0.366
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Prince AL, Watkin LB, Yin CC, Selin LK, Kang J, Schwartzberg PL, Berg LJ. Innate PLZF+CD4+ a? T cells develop and expand in the absence of Itk. J Immunol. 2014 Jul 15; 193(2):673-87.
Score: 0.366
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Yin CC, Cho OH, Sylvia KE, Narayan K, Prince AL, Evans JW, Kang J, Berg LJ. The Tec kinase ITK regulates thymic expansion, emigration, and maturation of ?d NKT cells. J Immunol. 2013 Mar 15; 190(6):2659-69.
Score: 0.333
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Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ. TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2794-802.
Score: 0.325
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Berg LJ. Strength of T cell receptor signaling strikes again. Immunity. 2009 Oct 16; 31(4):529-31.
Score: 0.265
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Felices M, Yin CC, Kosaka Y, Kang J, Berg LJ. Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proc Natl Acad Sci U S A. 2009 May 19; 106(20):8308-13.
Score: 0.256
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Prince AL, Yin CC, Enos ME, Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunol Rev. 2009 Mar; 228(1):115-31.
Score: 0.253
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Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. J Immunol. 2008 Mar 01; 180(5):3007-18.
Score: 0.236
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Lucas JA, Felices M, Evans JW, Berg LJ. Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk. J Immunol. 2007 Dec 01; 179(11):7561-7.
Score: 0.232
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Berg LJ. Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. Nat Rev Immunol. 2007 Jun; 7(6):479-85.
Score: 0.224
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Felices M, Falk M, Kosaka Y, Berg LJ. Tec kinases in T cell and mast cell signaling. Adv Immunol. 2007; 93:145-84.
Score: 0.218
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Kosaka Y, Felices M, Berg LJ. Itk and Th2 responses: action but no reaction. Trends Immunol. 2006 Oct; 27(10):453-60.
Score: 0.213
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Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ. The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. Immunity. 2006 Jul; 25(1):79-91.
Score: 0.211
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Atherly LO, Brehm MA, Welsh RM, Berg LJ. Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help. J Immunol. 2006 Feb 01; 176(3):1571-81.
Score: 0.205
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Li CR, Berg LJ. Itk is not essential for CD28 signaling in naive T cells. J Immunol. 2005 Apr 15; 174(8):4475-9.
Score: 0.194
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Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annu Rev Immunol. 2005; 23:549-600.
Score: 0.190
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Miller AT, Wilcox HM, Lai Z, Berg LJ. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet. Immunity. 2004 Jul; 21(1):67-80.
Score: 0.183
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Wilcox HM, Berg LJ. Itk phosphorylation sites are required for functional activity in primary T cells. J Biol Chem. 2003 Sep 26; 278(39):37112-21.
Score: 0.171
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Lucas JA, Miller AT, Atherly LO, Berg LJ. The role of Tec family kinases in T cell development and function. Immunol Rev. 2003 Feb; 191:119-38.
Score: 0.166
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Miller AT, Berg LJ. Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase. J Immunol. 2002 Mar 01; 168(5):2163-72.
Score: 0.156
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Gozalo-Sanmillan S, McNally JM, Lin MY, Chambers CA, Berg LJ. Cutting edge: two distinct mechanisms lead to impaired T cell homeostasis in Janus kinase 3- and CTLA-4-deficient mice. J Immunol. 2001 Jan 15; 166(2):727-30.
Score: 0.144
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Yang WC, Ching KA, Tsoukas CD, Berg LJ. Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain. J Immunol. 2001 Jan 01; 166(1):387-95.
Score: 0.144
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Baird AM, Lucas JA, Berg LJ. A profound deficiency in thymic progenitor cells in mice lacking Jak3. J Immunol. 2000 Oct 01; 165(7):3680-8.
Score: 0.141
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Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. J Biol Chem. 2000 Jan 21; 275(3):2219-30.
Score: 0.135
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Thomis DC, Aramburu J, Berg LJ. The Jak family tyrosine kinase Jak3 is required for IL-2 synthesis by naive/resting CD4+ T cells. J Immunol. 1999 Nov 15; 163(10):5411-7.
Score: 0.133
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Baird AM, Thomis DC, Berg LJ. T cell development and activation in Jak3-deficient mice. J Leukoc Biol. 1998 Jun; 63(6):669-77.
Score: 0.120
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Liu KQ, Bunnell SC, Gurniak CB, Berg LJ. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. J Exp Med. 1998 May 18; 187(10):1721-7.
Score: 0.120
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Thomis DC, Lee W, Berg LJ. T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis. J Immunol. 1997 Nov 15; 159(10):4708-19.
Score: 0.116
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Heyeck SD, Wilcox HM, Bunnell SC, Berg LJ. Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity. J Biol Chem. 1997 Oct 03; 272(40):25401-8.
Score: 0.115
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Thomis DC, Berg LJ. The role of Jak3 in lymphoid development, activation, and signaling. Curr Opin Immunol. 1997 Aug; 9(4):541-7.
Score: 0.114
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Thomis DC, Berg LJ. Peripheral expression of Jak3 is required to maintain T lymphocyte function. J Exp Med. 1997 Jan 20; 185(2):197-206.
Score: 0.109
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Gurniak CB, Thomis DC, Berg LJ. Genomic structure and promoter region of the murine Janus-family tyrosine kinase, Jak3. DNA Cell Biol. 1997 Jan; 16(1):85-94.
Score: 0.109
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Bunnell SC, Henry PA, Kolluri R, Kirchhausen T, Rickles RJ, Berg LJ. Identification of Itk/Tsk Src homology 3 domain ligands. J Biol Chem. 1996 Oct 11; 271(41):25646-56.
Score: 0.107
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Gurniak CB, Berg LJ. A new member of the Eph family of receptors that lacks protein tyrosine kinase activity. Oncogene. 1996 Aug 15; 13(4):777-86.
Score: 0.106
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Gurniak CB, Berg LJ. Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells. Blood. 1996 Apr 15; 87(8):3151-60.
Score: 0.104
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Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science. 1995 Nov 03; 270(5237):794-7.
Score: 0.101
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Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7.
Score: 0.088
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Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Sci Signal. 2013 Aug 27; 6(290):ra76.
Score: 0.086
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Heyeck SD, Berg LJ. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):669-73.
Score: 0.083
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Berg LJ. Signaling pathways that regulate T cell development and differentiation. J Immunol. 2012 Dec 15; 189(12):5487-8.
Score: 0.082
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Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Disrupting the intermolecular self-association of Itk enhances T cell signaling. J Immunol. 2010 Apr 15; 184(8):4228-35.
Score: 0.068
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Sacrist?n C, Schattgen SA, Berg LJ, Bunnell SC, Roy AL, Rosenstein Y. Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. Eur J Immunol. 2009 Sep; 39(9):2584-95.
Score: 0.066
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Mayack SR, Berg LJ. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. J Immunol. 2006 Feb 15; 176(4):2059-63.
Score: 0.051
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Soldevila G, Castellanos C, Malissen M, Berg LJ. Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization. Cell Immunol. 2001 Dec 15; 214(2):123-38.
Score: 0.038
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Grossman WJ, Verbsky JW, Yang L, Berg LJ, Fields LE, Chaplin DD, Ratner L. Dysregulated myelopoiesis in mice lacking Jak3. Blood. 1999 Aug 01; 94(3):932-9.
Score: 0.033
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Baird AM, Gerstein RM, Berg LJ. The role of cytokine receptor signaling in lymphocyte development. Curr Opin Immunol. 1999 Apr; 11(2):157-66.
Score: 0.032
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Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature. 1997 Jan 02; 385(6611):93-7.
Score: 0.027
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Lieberman SA, Spain LM, Wang L, Berg LJ. Enhanced T cell maturation and altered lineage commitment in T cell receptor/CD4-transgenic mice. Cell Immunol. 1995 Apr 15; 162(1):56-67.
Score: 0.024
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Wessel GM, Clark F, Berg L. A diversity of enzymes involved in the regulation of reversible tyrosine phosphorylation in sea urchin eggs and embryos. Comp Biochem Physiol B Biochem Mol Biol. 1995 Mar; 110(3):493-502.
Score: 0.024
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Durum SK, Cand?ias S, Nakajima H, Leonard WJ, Baird AM, Berg LJ, Muegge K. Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. J Exp Med. 1998 Dec 21; 188(12):2233-41.
Score: 0.008
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Kammer W, Lischke A, Moriggl R, Groner B, Ziemiecki A, Gurniak CB, Berg LJ, Friedrich K. Homodimerization of interleukin-4 receptor alpha chain can induce intracellular signaling. J Biol Chem. 1996 Sep 27; 271(39):23634-7.
Score: 0.007
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Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8891-5.
Score: 0.006
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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