LisaSpencerLisa Ann Spencer39.74403510000000-104.8360594000000014743Spencer, LisaAnnAssociate Professorprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonMatthewGreenhawtMatthew Jason Greenhawt39.74403510000000-104.8360594000000010823Greenhawt, MatthewProfessorIanCartwrightIan M Cartwright39.74403280000000-104.8408104000000011531Cartwright, IanAffiliateJaimeBelkind-GersonJaime Belkind-Gerson39.74403510000000-104.8360594000000011827Belkind-Gerson, JaimeAssociate Professor5Other Faculty1Professor3Asst Professor2Assoc Professor4InstructorJacobMarkJacob Alexander Mark39.74403510000000-104.8360594000000014251Mark, JacobAsst Professor13065 East 17th Avenue2TCHChildren's Hospital13065 East 17th AvenueAurora80045-2532CO8.183890.00801617238research areas1.033210.05674526coauthor of135.885.5770560similar to1143selected publicationsAuthorship 1877531Authorship 1877553Authorship 1877802Authorship 1877894Authorship 1878044Authorship 1878512Authorship 1878663Authorship 18787615Authorship 1878996Authorship 18790922Authorship 1879131Authorship 1879143Authorship 18793512Authorship 1879501Authorship 1879609Authorship 1879632Authorship 1879963Authorship 1880146Authorship 1880263Authorship 1880373Authorship 1880631Authorship 1880963Authorship 1881164Authorship 18813414Authorship 1881765Authorship 1881886Authorship 1881923Authorship 1881982Authorship 1882301Authorship 1882431Authorship 1882813Authorship 1883054Authorship 188306627683752Smith KM, Rahman RS, Spencer LAJournal of immunology (Baltimore, Md. : 1950)Smith KM, Rahman RS, Spencer LA. Humoral Immunity Provides Resident Intestinal Eosinophils Access to Luminal Antigen via Eosinophil-Expressed Low-Affinity Fc? Receptors. J Immunol. 2016 11 01; 197(9):3716-3724.J Immunol2016-09-28T00:00:002016Humoral Immunity Provides Resident Intestinal Eosinophils Access to Luminal Antigen via Eosinophil-Expressed Low-Affinity Fc? Receptors.30038615Carmo LAS, Bonjour K, Spencer LA, Weller PF, Melo RCNFrontiers in immunologyCarmo LAS, Bonjour K, Spencer LA, Weller PF, Melo RCN. Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma. Front Immunol. 2018; 9:1542.Front Immunol2018-07-09T00:00:002018Single-Cell Analyses of Human Eosinophils at High Resolution to Understand Compartmentalization and Vesicular Trafficking of Interferon-Gamma.29273402Sallis BF, Erkert L, Mo?ino-Romero S, Acar U, Wu R, Konnikova L, Lexmond WS, Hamilton MJ, Dunn WA, Szepfalusi Z, Vanderhoof JA, Snapper SB, Turner JR, Goldsmith JD, Spencer LA, Nurko S, Fiebiger EThe Journal of allergy and clinical immunologySallis BF, Erkert L, Mo?ino-Romero S, Acar U, Wu R, Konnikova L, Lexmond WS, Hamilton MJ, Dunn WA, Szepfalusi Z, Vanderhoof JA, Snapper SB, Turner JR, Goldsmith JD, Spencer LA, Nurko S, Fiebiger E. An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning. J Allergy Clin Immunol. 2018 04; 141(4):1354-1364.e9.J Allergy Clin Immunol2017-12-19T00:00:002017An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning.29281125Xenakis JJ, Howard ED, Smith KM, Olbrich CL, Huang Y, Anketell D, Maldonado S, Cornwell EW, Spencer LAImmunologyXenakis JJ, Howard ED, Smith KM, Olbrich CL, Huang Y, Anketell D, Maldonado S, Cornwell EW, Spencer LA. Resident intestinal eosinophils constitutively express antigen presentation markers and include two phenotypically distinct subsets of eosinophils. Immunology. 2018 06; 154(2):298-308.Immunology2018-01-21T00:00:002018Resident intestinal eosinophils constitutively express antigen presentation markers and include two phenotypically distinct subsets of eosinophils.30154112Ueki S, Tokunaga T, Melo RCN, Saito H, Honda K, Fukuchi M, Konno Y, Takeda M, Yamamoto Y, Hirokawa M, Fujieda S, Spencer LA, Weller PFBloodUeki S, Tokunaga T, Melo RCN, Saito H, Honda K, Fukuchi M, Konno Y, Takeda M, Yamamoto Y, Hirokawa M, Fujieda S, Spencer LA, Weller PF. Charcot-Leyden crystal formation is closely associated with eosinophil extracellular trap cell death. Blood. 2018 11 15; 132(20):2183-2187.Blood2018-08-28T00:00:002018Charcot-Leyden crystal formation is closely associated with eosinophil extracellular trap cell death.18727793Akuthota P, Wang HB, Spencer LA, Weller PFClinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyAkuthota P, Wang HB, Spencer LA, Weller PF. Immunoregulatory roles of eosinophils: a new look at a familiar cell. Clin Exp Allergy. 2008 Aug; 38(8):1254-63.Clin Exp Allergy2008-08-01T00:00:002008Immunoregulatory roles of eosinophils: a new look at a familiar cell.12128050Rajan TV, Ganley L, Paciorkowski N, Spencer L, Klei TR, Shultz LDExperimental parasitologyRajan TV, Ganley L, Paciorkowski N, Spencer L, Klei TR, Shultz LD. Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses. Exp Parasitol. 2002 Apr; 100(4):235-47.Exp Parasitol2002-04-01T00:00:002002Brugian infections in the peritoneal cavities of laboratory mice: kinetics of infection and cellular responses.22294786Shamri R, Melo RC, Young KM, Bivas-Benita M, Xenakis JJ, Spencer LA, Weller PFFASEB journal : official publication of the Federation of American Societies for Experimental BiologyShamri R, Melo RC, Young KM, Bivas-Benita M, Xenakis JJ, Spencer LA, Weller PF. CCL11 elicits secretion of RNases from mouse eosinophils and their cell-free granules. FASEB J. 2012 May; 26(5):2084-93.FASEB J2012-01-31T00:00:002012CCL11 elicits secretion of RNases from mouse eosinophils and their cell-free granules.18840671Spencer LA, Szela CT, Perez SA, Kirchhoffer CL, Neves JS, Radke AL, Weller PFJournal of leukocyte biologySpencer LA, Szela CT, Perez SA, Kirchhoffer CL, Neves JS, Radke AL, Weller PF. Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially. J Leukoc Biol. 2009 Jan; 85(1):117-23.J Leukoc Biol2008-10-07T00:00:002008Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially.15937360Spencer LA, Melo RC, Perez SA, Weller PFMethods in molecular biology (Clifton, N.J.)Spencer LA, Melo RC, Perez SA, Weller PF. A gel-based dual antibody capture and detection method for assaying of extracellular cytokine secretion: EliCell. Methods Mol Biol. 2005; 302:297-314.Methods Mol Biol2005-01-01T00:00:002005A gel-based dual antibody capture and detection method for assaying of extracellular cytokine secretion: EliCell.26447010Spencer L, Rollo M, Hauck Y, MacDonald-Wicks L, Wood L, Hutchesson M, Giglia R, Smith R, Collins CJBI database of systematic reviews and implementation reportsSpencer L, Rollo M, Hauck Y, MacDonald-Wicks L, Wood L, Hutchesson M, Giglia R, Smith R, Collins C. The effect of weight management interventions that include a diet component on weight-related outcomes in pregnant and postpartum women: a systematic review protocol. JBI Database System Rev Implement Rep. 2015 01; 13(1):88-98.JBI Database System Rev Implement Rep2015-01-01T00:00:002015The effect of weight management interventions that include a diet component on weight-related outcomes in pregnant and postpartum women: a systematic review protocol.25846339Liu LY, Wang H, Xenakis JJ, Spencer LAAllergyLiu LY, Wang H, Xenakis JJ, Spencer LA. Notch signaling mediates granulocyte-macrophage colony-stimulating factor priming-induced transendothelial migration of human eosinophils. Allergy. 2015 Jul; 70(7):805-12.Allergy2015-04-16T00:00:002015Notch signaling mediates granulocyte-macrophage colony-stimulating factor priming-induced transendothelial migration of human eosinophils.19017810Neves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PFProceedings of the National Academy of Sciences of the United States of AmericaNeves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PF. Eosinophil granules function extracellularly as receptor-mediated secretory organelles. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18478-83.Proc Natl Acad Sci U S A2008-11-18T00:00:002008Eosinophil granules function extracellularly as receptor-mediated secretory organelles.16138901Melo RC, Perez SA, Spencer LA, Dvorak AM, Weller PFTraffic (Copenhagen, Denmark)Melo RC, Perez SA, Spencer LA, Dvorak AM, Weller PF. Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils. Traffic. 2005 Oct; 6(10):866-79.Traffic2005-10-01T00:00:002005Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.25386174Spencer LA, Bonjour K, Melo RC, Weller PFFrontiers in immunologySpencer LA, Bonjour K, Melo RC, Weller PF. Eosinophil secretion of granule-derived cytokines. Front Immunol. 2014; 5:496.Front Immunol2014-10-27T00:00:002014Eosinophil secretion of granule-derived cytokines.16190985Melo RC, Spencer LA, Perez SA, Ghiran I, Dvorak AM, Weller PFTraffic (Copenhagen, Denmark)Melo RC, Spencer LA, Perez SA, Ghiran I, Dvorak AM, Weller PF. Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments. Traffic. 2005 Nov; 6(11):1047-57.Traffic2005-11-01T00:00:002005Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.21042920Shamri R, Xenakis JJ, Spencer LACell and tissue researchShamri R, Xenakis JJ, Spencer LA. Eosinophils in innate immunity: an evolving story. Cell Tissue Res. 2011 Jan; 343(1):57-83.Cell Tissue Res2010-11-03T00:00:002010Eosinophils in innate immunity: an evolving story.27393701Ueki S, Tokunaga T, Fujieda S, Honda K, Hirokawa M, Spencer LA, Weller PFCurrent allergy and asthma reportsUeki S, Tokunaga T, Fujieda S, Honda K, Hirokawa M, Spencer LA, Weller PF. Eosinophil ETosis and DNA Traps: a New Look at Eosinophilic Inflammation. Curr Allergy Asthma Rep. 2016 07; 16(8):54.Curr Allergy Asthma Rep2016-07-01T00:00:002016Eosinophil ETosis and DNA Traps: a New Look at Eosinophilic Inflammation.28891557Weller PF, Spencer LANature reviews. ImmunologyWeller PF, Spencer LA. Functions of tissue-resident eosinophils. Nat Rev Immunol. 2017 Dec; 17(12):746-760.Nat Rev Immunol2017-09-11T00:00:002017Functions of tissue-resident eosinophils.29672914Khoury P, Akuthota P, Ackerman SJ, Arron JR, Bochner BS, Collins MH, Kahn JE, Fulkerson PC, Gleich GJ, Gopal-Srivastava R, Jacobsen EA, Leiferman KM, Francesca LS, Mathur SK, Minnicozzi M, Prussin C, Rothenberg ME, Roufosse F, Sable K, Simon D, Simon HU, Spencer LA, Steinfeld J, Wardlaw AJ, Wechsler ME, Weller PF, Klion ADJournal of leukocyte biologyKhoury P, Akuthota P, Ackerman SJ, Arron JR, Bochner BS, Collins MH, Kahn JE, Fulkerson PC, Gleich GJ, Gopal-Srivastava R, Jacobsen EA, Leiferman KM, Francesca LS, Mathur SK, Minnicozzi M, Prussin C, Rothenberg ME, Roufosse F, Sable K, Simon D, Simon HU, Spencer LA, Steinfeld J, Wardlaw AJ, Wechsler ME, Weller PF, Klion AD. Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). J Leukoc Biol. 2018 07; 104(1):69-83.J Leukoc Biol2018-04-19T00:00:002018Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).20065995Spencer LA, Weller PFImmunology and cell biologySpencer LA, Weller PF. Eosinophils and Th2 immunity: contemporary insights. Immunol Cell Biol. 2010 Mar-Apr; 88(3):250-6.Immunol Cell Biol2010-01-12T00:00:002010Eosinophils and Th2 immunity: contemporary insights.23303825Ueki S, Melo RC, Ghiran I, Spencer LA, Dvorak AM, Weller PFBloodUeki S, Melo RC, Ghiran I, Spencer LA, Dvorak AM, Weller PF. Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. Blood. 2013 Mar 14; 121(11):2074-83.Blood2013-01-09T00:00:002013Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans.21885678Akuthota P, Melo RC, Spencer LA, Weller PFAmerican journal of respiratory cell and molecular biologyAkuthota P, Melo RC, Spencer LA, Weller PF. MHC Class II and CD9 in human eosinophils localize to detergent-resistant membrane microdomains. Am J Respir Cell Mol Biol. 2012 Feb; 46(2):188-95.Am J Respir Cell Mol Biol2011-09-01T00:00:002011MHC Class II and CD9 in human eosinophils localize to detergent-resistant membrane microdomains.23347072Melo RC, Liu L, Xenakis JJ, Spencer LAAllergyMelo RC, Liu L, Xenakis JJ, Spencer LA. Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion. Allergy. 2013 Mar; 68(3):274-84.Allergy2013-01-25T00:00:002013Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion.29803797Spergel JM, Aceves SS, Kliewer K, Gonsalves N, Chehade M, Wechsler JB, Groetch M, Friedlander J, Dellon ES, Book W, Hirano I, Muir AB, Cianferoni A, Spencer L, Liacouras CA, Cheng E, Kottyan L, Wen T, Platts-Mills T, Rothenberg METhe Journal of allergy and clinical immunologySpergel JM, Aceves SS, Kliewer K, Gonsalves N, Chehade M, Wechsler JB, Groetch M, Friedlander J, Dellon ES, Book W, Hirano I, Muir AB, Cianferoni A, Spencer L, Liacouras CA, Cheng E, Kottyan L, Wen T, Platts-Mills T, Rothenberg ME. New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2018 07; 142(1):48-53.J Allergy Clin Immunol2018-05-24T00:00:002018New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting.19328806Neves JS, Perez SA, Spencer LA, Melo RC, Weller PFJournal of immunological methodsNeves JS, Perez SA, Spencer LA, Melo RC, Weller PF. Subcellular fractionation of human eosinophils: isolation of functional specific granules on isoosmotic density gradients. J Immunol Methods. 2009 May 15; 344(1):64-72.J Immunol Methods2009-03-26T00:00:002009Subcellular fractionation of human eosinophils: isolation of functional specific granules on isoosmotic density gradients.19398958Melo RC, Spencer LA, Perez SA, Neves JS, Bafford SP, Morgan ES, Dvorak AM, Weller PFLaboratory investigation; a journal of technical methods and pathologyMelo RC, Spencer LA, Perez SA, Neves JS, Bafford SP, Morgan ES, Dvorak AM, Weller PF. Vesicle-mediated secretion of human eosinophil granule-derived major basic protein. Lab Invest. 2009 Jul; 89(7):769-81.Lab Invest2009-04-27T00:00:002009Vesicle-mediated secretion of human eosinophil granule-derived major basic protein.16492782Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PFProceedings of the National Academy of Sciences of the United States of AmericaSpencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF. Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3333-8.Proc Natl Acad Sci U S A2006-02-21T00:00:002006Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.26965633Carmo LA, Bonjour K, Ueki S, Neves JS, Liu L, Spencer LA, Dvorak AM, Weller PF, Melo RCJournal of leukocyte biologyCarmo LA, Bonjour K, Ueki S, Neves JS, Liu L, Spencer LA, Dvorak AM, Weller PF, Melo RC. CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils. J Leukoc Biol. 2016 08; 100(2):391-401.J Leukoc Biol2016-03-10T00:00:002016CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils.17875811Melo RC, Spencer LA, Dvorak AM, Weller PFJournal of leukocyte biologyMelo RC, Spencer LA, Dvorak AM, Weller PF. Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins. J Leukoc Biol. 2008 Feb; 83(2):229-36.J Leukoc Biol2007-09-17T00:00:002007Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins.19171875Radke AL, Reynolds LE, Melo RC, Dvorak AM, Weller PF, Spencer LABloodRadke AL, Reynolds LE, Melo RC, Dvorak AM, Weller PF, Spencer LA. Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation. Blood. 2009 Mar 26; 113(13):3092-101.Blood2009-01-26T00:00:002009Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation.11702065Larregina AT, Morelli AE, Spencer LA, Logar AJ, Watkins SC, Thomson AW, Falo LDNature immunologyLarregina AT, Morelli AE, Spencer LA, Logar AJ, Watkins SC, Thomson AW, Falo LD. Dermal-resident CD14+ cells differentiate into Langerhans cells. Nat Immunol. 2001 Dec; 2(12):1151-8.Nat Immunol2001-12-01T00:00:002001Dermal-resident CD14+ cells differentiate into Langerhans cells.26147683Bettigole SE, Lis R, Adoro S, Lee AH, Spencer LA, Weller PF, Glimcher LHNature immunologyBettigole SE, Lis R, Adoro S, Lee AH, Spencer LA, Weller PF, Glimcher LH. The transcription factor XBP1 is selectively required for eosinophil differentiation. Nat Immunol. 2015 Aug; 16(8):829-37.Nat Immunol2015-07-06T00:00:002015The transcription factor XBP1 is selectively required for eosinophil differentiation.2015-12-31NIHSPENCER, LISA ANN2010-01-18Notch signaling-mediated functions of airway eosinophils in lung diseaseR01HL0956992022-02-28NIHSPENCER, LISA ANN2017-03-07Eosinophil functions in allergic gastrointestinal diseasesR01AI121186Principal InvestigatorPrincipal InvestigatorD004802Disorders631770.846189EosinophiliaAuthorship 202469631203469Ueki S, Miyabe Y, Yamamoto Y, Fukuchi M, Hirokawa M, Spencer LA, Weller PFCurrent allergy and asthma reportsUeki S, Miyabe Y, Yamamoto Y, Fukuchi M, Hirokawa M, Spencer LA, Weller PF. Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation. Curr Allergy Asthma Rep. 2019 06 15; 19(8):35.Curr Allergy Asthma Rep2019-06-15T00:00:002019Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation.PULM&SLEEPMEDAuthorship 203593531273593Olbrich CL, Simerly L, de Zoeten EF, Furuta GT, Spencer LADigestive diseases and sciencesOlbrich CL, Simerly L, de Zoeten EF, Furuta GT, Spencer LA. Climbing New Mountains: How Antibodies Blocking a4?7 Integrins Tamed Eosinophilic Inflammation of the Intestinal Tract. Dig Dis Sci. 2019 08; 64(8):2068-2071.Dig Dis Sci2019-08-01T00:00:002019Climbing New Mountains: How Antibodies Blocking a4?7 Integrins Tamed Eosinophilic Inflammation of the Intestinal Tract.D006967Disorders1062590.758981HypersensitivityD004751Disorders25770.909044EnteritisAuthorship 204231631302821Ueki S, Miyabe Y, Yamamoto Y, Fukuchi M, Hirokawa M, Spencer LA, Weller PFCurrent allergy and asthma reportsUeki S, Miyabe Y, Yamamoto Y, Fukuchi M, Hirokawa M, Spencer LA, Weller PF. Correction to: Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation. Curr Allergy Asthma Rep. 2019 Jul 13; 19(8):38.Curr Allergy Asthma Rep2019-07-13T00:00:002019Correction to: Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation.D004804Anatomy952730.835556EosinophilsD007421Anatomy911350.900945Intestine, SmallSOM-MEDSOM-PEDSAllergyImmunGastroGastroenterologyUniversity of Colorado Denver - Anschutz Medical CampusRobertKramerRobert E Kramer39.74403510000000-104.836059400000001406Kramer, RobertProfessorEdwindeZoetenEdwin F deZoeten39.74403510000000-104.836059400000001562deZoeten, Edwin0000-0002-0946-9759ProfessorSeanColganSean P Colgan39.74515960000000-104.840628000000002441Colgan, SeanDistinguished ProfessorGlennFurutaGlenn T Furuta39.74403510000000-104.836059400000002676Furuta, GlennProfessorChristyJonesChristy M Jones39.74403510000000-104.836059400000002869Jones, ChristySenior InstructorJoanneMasterson+ucBYbO51wfQKB4zaXjYjFFGSoYfD0+wHFBWvvLDHw==Joanne Carole Masterson39.74403510000000-104.836059400000003200Masterson, JoanneAsst Professor AdjointCaliesMenard-KatcherCalies DeSiato Menard-Katcher39.74403510000000-104.836059400000006086Menard-Katcher, CaliesAssociate ProfessorAuthorship 2215301132518365Olbrich CL, Bivas-Benita M, Xenakis JJ, Maldonado S, Cornwell E, Fink J, Yuan Q, Gill N, Mansfield R, Dockstader K, Spencer LAMucosal immunologyOlbrich CL, Bivas-Benita M, Xenakis JJ, Maldonado S, Cornwell E, Fink J, Yuan Q, Gill N, Mansfield R, Dockstader K, Spencer LA. Remote allergen exposure elicits eosinophil infiltration into allergen nonexposed mucosal organs and primes for allergic inflammation. Mucosal Immunol. 2020 09; 13(5):777-787.Mucosal Immunol2020-06-09T00:00:002020Remote allergen exposure elicits eosinophil infiltration into allergen nonexposed mucosal organs and primes for allergic inflammation.Authorship 2362695Authorship 234829333486741Olbrich CL, Larsen LD, Spencer LAMethods in molecular biology (Clifton, N.J.)Olbrich CL, Larsen LD, Spencer LA. Assessing Phenotypic Heterogeneity in Intestinal Tissue Eosinophils. Methods Mol Biol. 2021; 2241:243-255.Methods Mol Biol2021-01-01T00:00:002021Assessing Phenotypic Heterogeneity in Intestinal Tissue Eosinophils.33671475Masterson JC, Menard-Katcher C, Larsen LD, Furuta GT, Spencer LACellsMasterson JC, Menard-Katcher C, Larsen LD, Furuta GT, Spencer LA. Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies. Cells. 2021 02 17; 10(2).Cells2021-02-17T00:00:002021Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies.Authorship 241565234086396Ruppe LB, Spencer LA, Kriebs JMJournal of midwifery & women's healthRuppe LB, Spencer LA, Kriebs JM. Pre-Exposure Prophylaxis for HIV Infection and the Role of the Women's Health Care Provider in HIV Prevention. J Midwifery Womens Health. 2021 May; 66(3):322-333.J Midwifery Womens Health2021-06-04T00:00:002021Pre-Exposure Prophylaxis for HIV Infection and the Role of the Women's Health Care Provider in HIV Prevention.Authorship 256502535141942Larsen LD, Dockstader K, Olbrich CL, Cartwright IM, Spencer LAJournal of leukocyte biologyLarsen LD, Dockstader K, Olbrich CL, Cartwright IM, Spencer LA. Modulation of surface CD11c expression tracks plasticity in murine intestinal tissue eosinophils. J Leukoc Biol. 2022 05; 111(5):943-952.J Leukoc Biol2022-02-09T00:00:002022Modulation of surface CD11c expression tracks plasticity in murine intestinal tissue eosinophils.StanleySzeflerStanley J Szefler39.74403510000000-104.836059400000008115Szefler, StanleyProfessorAuthorship 2725859Authorship 273184436273270Menard-Katcher C, Liu C, Galbraith MD, Benson T, Burger C, Dobias D, Larsen L, O'Brien C, Spencer LA, Furuta GT, Masterson JCAllergyMenard-Katcher C, Liu C, Galbraith MD, Benson T, Burger C, Dobias D, Larsen L, O'Brien C, Spencer LA, Furuta GT, Masterson JC. Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature. Allergy. 2023 02; 78(2):579-583.Allergy2022-11-05T00:00:002022Fibrostenotic eosinophilic esophagitis phenotype is defined by a proliferative gene signature.36064648Quinn L, Nguyen B, Menard-Katcher C, Spencer LDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverQuinn L, Nguyen B, Menard-Katcher C, Spencer L. IgG4+ cells are increased in the gastrointestinal tissue of pediatric patients with active eosinophilic gastritis and duodenitis and decrease in remission. Dig Liver Dis. 2023 01; 55(1):53-60.Dig Liver Dis2022-09-03T00:00:002022IgG4+ cells are increased in the gastrointestinal tissue of pediatric patients with active eosinophilic gastritis and duodenitis and decrease in remission.true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Senior InstructorSenior Instructortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Asst Professor AdjointAsst Professor Adjointtrue1Asst ProfessorAsst Professortrue1ProfessorProfessortrue1Distinguished ProfessorDistinguished Professortrue1AffiliateAffiliateAmyFeldmanAmy G. Feldman39.74403510000000-104.836059400000008787Feldman, AmyAssociate Professor