NoahJohnsonNoah Ray Johnson39.74528180000000-104.8375727000000014592Johnson, NoahRay0000-0002-0969-0066Asst Professor-Researchprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:grantAwardedBygrant awarded byprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:trainingAtOrganizationeducational organizationprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provinceAgreementvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:degreeEarneddegree earnedDepartmentvivo:educationalTrainingeducation and trainingEducational TrainingGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:majorFieldmajor field of degreevivo:middleNamemiddle name or initialvivo:orcidIdORCID idvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofRolevivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonHeidiChialHeidi Chial39.74528180000000-104.8375727000000010540Chial, HeidiAsst Professor-Research1Professor3Asst Professor2Assoc Professor4InstructorAndrewBubakAndrew Noel Bubak39.74528180000000-104.8375727000000012567Bubak, AndrewAsst Professor-ResearchChristinaVaughanChristina Lynn Vaughan39.74528180000000-104.8375727000000013165Vaughan, ChristinaAssociate Professor13001 East 17th Place2SOMSchool of Medicine13001 East 17th PlaceAurora80045-2570CO1.746990.0147294193research areas1.193890.047258413coauthor of23.81083.6403360similar to1129selected publicationsD024801Disorders7100.974087TauopathiesD006493Chemicals & Drugs1472400.871705HeparinD014945Physiology1762790.817641Wound HealingBrianSauerBrian Sauer39.74528180000000-104.8375727000000015657Sauer, BrianAsst ProfessorD016875Chemicals & Drugs44800.934675tau ProteinsD004337Chemicals & Drugs511180.903914Drug CarriersSOM-NEUR General OperationsChemical & Biological EnginSOP-AdministrationUniversity of Colorado BoulderUniversity of Colorado Denver - Anschutz Medical CampusJohnSladek Jr.John R. Sladek Jr.39.74528180000000-104.837572700000001647Sladek Jr., JohnProfessor-ClinicalMariaNagelMaria Acena Nagel39.74515960000000-104.840628000000001733Nagel, MariaProfessor-ResearchChristinaCoughlanChristina Mary Coughlan39.74528180000000-104.837572700000003334Coughlan, ChristinaAsst Professor-ResearchRajeshAgarwalRajesh Agarwal39.74688660000000-104.838256700000004238Agarwal, RajeshProfessorHuntingtonPotterHuntington Potter39.74528180000000-104.837572700000005666Potter, HuntingtonProfessorKristiAnsethKristi S Anseth40.00830860000000-105.24906720000000856Anseth, KristiDistinguished ProfessorUdayaKompellaUdaya B. Kompella39.74688660000000-104.838256700000004276Kompella, UdayaProfessorAuthorship 210769431665341Bubak AN, Como CN, Coughlan CM, Johnson NR, Hassell JE, Mescher T, Niemeyer CS, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Russ HA, Nagel MAThe Journal of infectious diseasesBubak AN, Como CN, Coughlan CM, Johnson NR, Hassell JE, Mescher T, Niemeyer CS, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Russ HA, Nagel MA. Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-?, and an Amyloidogenic Extracellular Environment. J Infect Dis. 2020 03 16; 221(7):1088-1097.J Infect Dis2020-03-16T00:00:002020Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-?, and an Amyloidogenic Extracellular Environment.Authorship 225465532809013Bubak AN, Beseler C, Como CN, Coughlan CM, Johnson NR, Hassell JE, Burnet AM, Mescher T, Schmid DS, Coleman C, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Shilleh AH, Russ HA, Nagel MAThe Journal of infectious diseasesBubak AN, Beseler C, Como CN, Coughlan CM, Johnson NR, Hassell JE, Burnet AM, Mescher T, Schmid DS, Coleman C, Mahalingam R, Cohrs RJ, Boyd TD, Potter H, Shilleh AH, Russ HA, Nagel MA. Amylin, A?42, and Amyloid in Varicella Zoster Virus Vasculopathy Cerebrospinal Fluid and Infected Vascular Cells. J Infect Dis. 2021 04 08; 223(7):1284-1294.J Infect Dis2021-04-08T00:00:002021Amylin, A?42, and Amyloid in Varicella Zoster Virus Vasculopathy Cerebrospinal Fluid and Infected Vascular Cells.34603007Ahmed MM, Johnson NR, Boyd TD, Coughlan C, Chial HJ, Potter HFrontiers in aging neuroscienceAhmed MM, Johnson NR, Boyd TD, Coughlan C, Chial HJ, Potter H. Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners? Front Aging Neurosci. 2021; 13:718426.Front Aging Neurosci2021-09-16T00:00:002021Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?JasonBurdickJason A Burdick20550Burdick, JasonProfessor11/2014University of PittsburghUniversity of Pittsburgh, Biomedical EngineeringPhDBiomedical Engineering07/2018University of California, San FranciscoUniversity of California, San Francisco, Neuroscience/NeurologyPostdocNeuroscience/NeurologyAuthorship 2621901Authorship 2621911Authorship 2621921Authorship 2621932Authorship 2621941Authorship 2621951Authorship 2621965Authorship 2621972Authorship 2621982Authorship 2621991Authorship 2622007Authorship 2622012Authorship 2622026Authorship 2622037Authorship 2622046Authorship 2622051Authorship 2622062Authorship 2622074Authorship 2622081Authorship 2622091Authorship 2622102Authorship 2622112Authorship 262212124075887Johnson NR, Ambe T, Wang YActa biomaterialiaJohnson NR, Ambe T, Wang Y. Lysine-based polycation:heparin coacervate for controlled protein delivery. Acta Biomater. 2014 Jan; 10(1):40-6.Acta Biomater2013-09-25T00:00:002013Lysine-based polycation:heparin coacervate for controlled protein delivery.23690982Johnson NR, Wang YPloS oneJohnson NR, Wang Y. Controlled delivery of sonic hedgehog morphogen and its potential for cardiac repair. PLoS One. 2013; 8(5):e63075.PLoS One2013-05-14T00:00:002013Controlled delivery of sonic hedgehog morphogen and its potential for cardiac repair.22364506Upadhyayula S, Quinata T, Bishop S, Gupta S, Johnson NR, Bahmani B, Bozhilov K, Stubbs J, Jreij P, Nallagatla P, Vullev VILangmuir : the ACS journal of surfaces and colloidsUpadhyayula S, Quinata T, Bishop S, Gupta S, Johnson NR, Bahmani B, Bozhilov K, Stubbs J, Jreij P, Nallagatla P, Vullev VI. Coatings of polyethylene glycol for suppressing adhesion between solid microspheres and flat surfaces. Langmuir. 2012 Mar 20; 28(11):5059-69.Langmuir2012-03-09T00:00:002012Coatings of polyethylene glycol for suppressing adhesion between solid microspheres and flat surfaces.29203673Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SBProceedings of the National Academy of Sciences of the United States of AmericaJohnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):E11029-E11036.Proc Natl Acad Sci U S A2017-12-04T00:00:002017Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.28837163St?hr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WFNature chemistrySt?hr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nat Chem. 2017 09; 9(9):874-881.Nat Chem2017-04-03T00:00:002017A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.26722220Zhou Y, Zhang H, Zheng B, Ye L, Zhu S, Johnson NR, Wang Z, Wei X, Chen D, Cao G, Fu X, Li X, Xu HZ, Xiao JInternational journal of biological sciencesZhou Y, Zhang H, Zheng B, Ye L, Zhu S, Johnson NR, Wang Z, Wei X, Chen D, Cao G, Fu X, Li X, Xu HZ, Xiao J. Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury. Int J Biol Sci. 2016; 12(1):87-99.Int J Biol Sci2016-01-01T00:00:002016Retinoic Acid Induced-Autophagic Flux Inhibits ER-Stress Dependent Apoptosis and Prevents Disruption of Blood-Spinal Cord Barrier after Spinal Cord Injury.25836592Awada HK, Johnson NR, Wang YJournal of controlled release : official journal of the Controlled Release SocietyAwada HK, Johnson NR, Wang Y. Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. J Control Release. 2015 Jun 10; 207:7-17.J Control Release2015-03-31T00:00:002015Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction.25138695Johnson NR, Wang YExpert opinion on drug deliveryJohnson NR, Wang Y. Coacervate delivery systems for proteins and small molecule drugs. Expert Opin Drug Deliv. 2014 Dec; 11(12):1829-32.Expert Opin Drug Deliv2014-08-19T00:00:002014Coacervate delivery systems for proteins and small molecule drugs.23154193Johnson NR, Wang YJournal of controlled release : official journal of the Controlled Release SocietyJohnson NR, Wang Y. Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. J Control Release. 2013 Mar 10; 166(2):124-9.J Control Release2012-11-12T00:00:002012Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing.27493838Cai P, Ye J, Zhu J, Liu D, Chen D, Wei X, Johnson NR, Wang Z, Zhang H, Cao G, Xiao J, Ye J, Lin LAging and diseaseCai P, Ye J, Zhu J, Liu D, Chen D, Wei X, Johnson NR, Wang Z, Zhang H, Cao G, Xiao J, Ye J, Lin L. Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson's Disease Model. Aging Dis. 2016 Aug; 7(4):336-449.Aging Dis2016-01-17T00:00:002016Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson's Disease Model.26045801Cheng Y, Zhang J, Deng L, Johnson NR, Yu X, Zhang N, Lou T, Zhang Y, Wei X, Chen Z, He S, Li X, Xiao JInternational journal of clinical and experimental pathologyCheng Y, Zhang J, Deng L, Johnson NR, Yu X, Zhang N, Lou T, Zhang Y, Wei X, Chen Z, He S, Li X, Xiao J. Intravenously delivered neural stem cells migrate into ischemic brain, differentiate and improve functional recovery after transient ischemic stroke in adult rats. Int J Clin Exp Pathol. 2015; 8(3):2928-36.Int J Clin Exp Pathol2015-03-01T00:00:002015Intravenously delivered neural stem cells migrate into ischemic brain, differentiate and improve functional recovery after transient ischemic stroke in adult rats.25658378Johnson NR, Wang YCurrent pharmaceutical biotechnologyJohnson NR, Wang Y. Drug delivery systems for wound healing. Curr Pharm Biotechnol. 2015; 16(7):621-9.Curr Pharm Biotechnol2015-01-01T00:00:002015Drug delivery systems for wound healing.26687235Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao JMolecular neurobiologyWang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J. bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury. Mol Neurobiol. 2016 12; 53(10):7298-7311.Mol Neurobiol2015-12-21T00:00:002015bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.26032846Johnson NR, Wang YWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyJohnson NR, Wang Y. Coacervate delivery of HB-EGF accelerates healing of type 2 diabetic wounds. Wound Repair Regen. 2015 Jul-Aug; 23(4):591-600.Wound Repair Regen2015-07-27T00:00:002015Coacervate delivery of HB-EGF accelerates healing of type 2 diabetic wounds.26179034Johnson NR, Wang YMethods in molecular biology (Clifton, N.J.)Johnson NR, Wang Y. Controlled Delivery of Sonic Hedgehog with a Heparin-Based Coacervate. Methods Mol Biol. 2015; 1322:1-7.Methods Mol Biol2015-01-01T00:00:002015Controlled Delivery of Sonic Hedgehog with a Heparin-Based Coacervate.35445427Johnson NRBioEssays : news and reviews in molecular, cellular and developmental biologyJohnson NR. Tau acetylation reduces its autophagic degradation and is a targetable pathway for human tauopathies. Bioessays. 2022 06; 44(6):e2200062.Bioessays2022-04-20T00:00:002022Tau acetylation reduces its autophagic degradation and is a targetable pathway for human tauopathies.28315407Long DW, Johnson NR, Jeffries EM, Hara H, Wang YJournal of controlled release : official journal of the Controlled Release SocietyLong DW, Johnson NR, Jeffries EM, Hara H, Wang Y. Controlled delivery of platelet-derived proteins enhances porcine wound healing. J Control Release. 2017 05 10; 253:73-81.J Control Release2017-03-14T00:00:002017Controlled delivery of platelet-derived proteins enhances porcine wound healing.23884640Li H, Johnson NR, Usas A, Lu A, Poddar M, Wang Y, Huard JStem cells translational medicineLi H, Johnson NR, Usas A, Lu A, Poddar M, Wang Y, Huard J. Sustained release of bone morphogenetic protein 2 via coacervate improves the osteogenic potential of muscle-derived stem cells. Stem Cells Transl Med. 2013 Sep; 2(9):667-77.Stem Cells Transl Med2013-07-24T00:00:002013Sustained release of bone morphogenetic protein 2 via coacervate improves the osteogenic potential of muscle-derived stem cells.21118705Chu H, Johnson NR, Mason NS, Wang YJournal of controlled release : official journal of the Controlled Release SocietyChu H, Johnson NR, Mason NS, Wang Y. A [polycation:heparin] complex releases growth factors with enhanced bioactivity. J Control Release. 2011 Mar 10; 150(2):157-63.J Control Release2010-11-29T00:00:002010A [polycation:heparin] complex releases growth factors with enhanced bioactivity.24452960Awada HK, Johnson NR, Wang YMacromolecular bioscienceAwada HK, Johnson NR, Wang Y. Dual delivery of vascular endothelial growth factor and hepatocyte growth factor coacervate displays strong angiogenic effects. Macromol Biosci. 2014 May; 14(5):679-86.Macromol Biosci2014-01-23T00:00:002014Dual delivery of vascular endothelial growth factor and hepatocyte growth factor coacervate displays strong angiogenic effects.33445252Johnson NR, Kruger M, Goetsch KP, Zilla P, Bezuidenhout D, Wang Y, Davies NHACS biomaterials science & engineeringJohnson NR, Kruger M, Goetsch KP, Zilla P, Bezuidenhout D, Wang Y, Davies NH. Coacervate Delivery of Growth Factors Combined with a Degradable Hydrogel Preserves Heart Function after Myocardial Infarction. ACS Biomater Sci Eng. 2015 Sep 14; 1(9):753-759.ACS Biomater Sci Eng2015-08-10T00:00:002015Coacervate Delivery of Growth Factors Combined with a Degradable Hydrogel Preserves Heart Function after Myocardial Infarction.24060423Lee KW, Johnson NR, Gao J, Wang YBiomaterialsLee KW, Johnson NR, Gao J, Wang Y. Human progenitor cell recruitment via SDF-1a coacervate-laden PGS vascular grafts. Biomaterials. 2013 Dec; 34(38):9877-85.Biomaterials2013-09-20T00:00:002013Human progenitor cell recruitment via SDF-1a coacervate-laden PGS vascular grafts.35768831Johnson NR, Wang AC, Coughlan C, Sillau S, Lucero E, Viltz L, Markham N, Allen C, Dhanasekaran AR, Chial HJ, Potter HAlzheimer's research & therapyJohnson NR, Wang AC, Coughlan C, Sillau S, Lucero E, Viltz L, Markham N, Allen C, Dhanasekaran AR, Chial HJ, Potter H. Imipramine and olanzapine block apoE4-catalyzed polymerization of A? and show evidence of improving Alzheimer's disease cognition. Alzheimers Res Ther. 2022 06 29; 14(1):88.Alzheimers Res Ther2022-06-29T00:00:002022Imipramine and olanzapine block apoE4-catalyzed polymerization of A? and show evidence of improving Alzheimer's disease cognition.Authorship 275527335950643Rocker AJ, Cavasin M, Johnson NR, Shandas R, Park DACS biomaterials science & engineeringRocker AJ, Cavasin M, Johnson NR, Shandas R, Park D. Sulfonated Thermoresponsive Injectable Gel for Sequential Release of Therapeutic Proteins to Protect Cardiac Function after Myocardial Infarction. ACS Biomater Sci Eng. 2022 09 12; 8(9):3883-3898.ACS Biomater Sci Eng2022-08-11T00:00:002022Sulfonated Thermoresponsive Injectable Gel for Sequential Release of Therapeutic Proteins to Protect Cardiac Function after Myocardial Infarction.Authorship 2822291Authorship 2822301Authorship 282231336624100Johnson NR, Yuan P, Castillo E, Lopez TP, Yue W, Bond A, Rivera BM, Sullivan MC, Hirouchi M, Giles K, Aoyagi A, Condello CNature communicationsJohnson NR, Yuan P, Castillo E, Lopez TP, Yue W, Bond A, Rivera BM, Sullivan MC, Hirouchi M, Giles K, Aoyagi A, Condello C. CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model. Nat Commun. 2023 01 09; 14(1):118.Nat Commun2023-01-09T00:00:002023CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model.36276634Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJNature machine intelligenceWong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ. Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics. Nat Mach Intell. 2022 Jun; 4(6):583-595.Nat Mach Intell2022-05-30T00:00:002022Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics.2026-06-30NIHJOHNSON, NOAH RAY2023-07-15Investigating and targeting apolipoprotein E4 in Down syndrome-associated Alzheimer's diseaseRF1AG0789652024-11-30NIHPARK, DAE WON2022-12-15Determining the role of tissue stiffness in the development of Alzheimer's disease pathologyR21AG080257Principal InvestigatorCo-Principal Investigatortrue1Professor-ResearchProfessor-Researchtrue1Professor-ClinicalProfessor-Clinicaltrue1ProfessorProfessortrue1Asst ProfessorAsst Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Asst Professor-ResearchAsst Professor-Researchtrue1Asst Professor-ResearchAsst Professor-Researchtrue1ProfessorProfessortrue1Senior InstructorSenior Instructortrue1Asst Professor-ResearchAsst Professor-Researchtrue1Distinguished ProfessorDistinguished Professortrue1Associate ProfessorAssociate Professortrue1Asst Professor-ResearchAsst Professor-ResearchJessicaBarrJessica P. Barr39.74528180000000-104.837572700000008602Barr, JessicaSenior Instructor