Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Jenna Demedis

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

    Collapse Biography 
    Collapse education and training
    University of California, Los Angeles, Los Angeles, CAB.S.06/2008Psychobiology
    Vanderbilt University School of Medicine, Nashville, TNM.D.05/2012Medicine
    University of Colorado School of Medicine, Aurora, CO06/2015Pediatrics (Residency)
    University of Colorado School of Medicine, Aurora, CO06/2018Pediatric Hematology/Oncology/BMT (Fellowship)
    University of Colorado, Aurora, COM.S.05/2018Master of Science - Clinical Science
    Collapse awards and honors
    2018Consortium Young Investigator Travel Award, Pediatric Blood and Marrow Transplant
    2018 - 2019Tanabe-Bobrow Family Young Investigator Award Endowed Fund, Children's Hospital Colorado

    Collapse Overview 
    Collapse overview
    Dr. Jenna Demedis is an Assistant Professor in the Division of Hematology/Oncology/Bone Marrow Transplantation at the University of Colorado School of Medicine. Dr. Demedis’s clinical focus is on taking care of children, adolescents and young adults with pediatric solid tumors of all types, as well as caring for survivors of pediatric cancers. Dr. Demedis’s clinical research career focuses on improving pediatric oncology outcomes, late effects from cancer, and patient quality of life. She has a specific interest in adolescent and young adult survivorship and sexual health. Dr. Demedis utilizes observational study design, Dissemination and Implementation science methods, and qualitative/mixed methods in her research.

    Collapse Research 
    Collapse research activities and funding
    K08CA263192     (DEMEDIS, JENNA)Jul 21, 2022 - Jun 30, 2027
    NIH
    Implementation and Evaluation of a Screening Tool for Sexual Dysfunction for Pediatric Cancer Survivors
    Role: Principal Investigator
         (Jenna Sopfe)Jul 1, 2017 - Jun 30, 2019
    Thrasher Research Fund
    Evaluation of Malglycemia in the Pediatric Hematopoietic Stem Cell Transplant Population
    Role: Principal Investigator
         (Jenna Sopfe)Jul 1, 2017 - Jun 30, 2018
    Cancer League of Colorado
    Evaluation of Malglycemia in the Pediatric Hematopoietic Stem Cell Transplant Population
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Beauchemin MP, Dupuis LL, Aftandilian C, Agarwal V, Baggott C, Bradfield SM, Cannone D, Caywood EH, Crellin-Parsons N, Demedis J, Dickens D, Esbenshade AJ, Freyer DR, Grimes AC, Kelly KM, King AA, Klesges LM, Kyono W, Nagasubramanian R, Orgel E, Orsey AD, Roth ME, Sherani F, Vettese E, Walsh A, Woods-Swafford W, Yu LC, Tomlinson GA, Sung L. Factors associated with unplanned healthcare encounters in pediatric cancer patients. Support Care Cancer. 2026 May 21; 34(6). PMID: 42165869.
      View in: PubMed
    2. Demedis J, Reedy J, Chow EJ, Peterson PN, Dorsey B, Studts CR. Provider-Engaged Development of a Sexual Dysfunction Screening Approach for Adolescents and Young Adult Childhood Cancer Survivors: Iterative Co-Design Study. JMIR Form Res. 2026 Apr 08; 10:e85905. PMID: 41950298.
      View in: PubMed
    3. Frederick NN, Bennett A, Bingen K, Cherven B, Chevalier LL, Demedis J, Freyer DR, Nguyen A, Nowobilski MK, Pitter T, Quinn GP, Bober SL. The Development and Refinement of a Web-Based Sexual Health Education Intervention for Pediatric Oncology Physicians and Advanced Practice Providers Caring for Adolescents and Young Adults With Cancer. Pediatr Blood Cancer. 2026 May; 73(5):e70200. PMID: 41834222.
      View in: PubMed
    4. Hernandez LE, Smitherman AB, Santacroce SJ, Liu Y, Roy MM, Ross WL, Armstrong H, Appel B, Casillas J, Hurtado-de-Mendoza A, Demedis J, Horwitz LI, Mendoza JA, Kadan-Lottick NS. Childhood cancer survivors and their caregivers are amenable to survivorship surveillance with community-based primary care providers. J Cancer Surviv. 2025 Nov 27. PMID: 41310100.
      View in: PubMed
    5. Yan AP, Dupuis LL, Aftandilian C, Agarwal V, Baggott C, Beauchemin MP, Bradfield SM, Cannone D, Caywood EH, Crellin-Parsons N, Demedis J, Dickens D, Esbenshade AJ, Freyer DR, Grimes AC, Kelly KM, King AA, Klesges LM, Kyono W, Nagasubramanian R, Orgel E, Orsey AD, Roth ME, Sherani F, Vettese E, Walsh A, Woods-Swafford W, Yu LC, Tomlinson GA, Sung L. Factors Associated With Symptom Burden Among Pediatric Patients With Cancer. JCO Oncol Pract. 2026 Jun; 22(6):1087-1095. PMID: 40811761.
      View in: PubMed
    6. Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris MR, Adams DL, Hayashi M. Single-Cell RNA Sequencing of Ewing Sarcoma Tumors Demonstrates Transcriptional Heterogeneity and Clonal Evolution. Clin Cancer Res. 2025 May 15; 31(10):2010-2023. PMID: 40029262.
      View in: PubMed
    7. Cherven B, Fitch K, Esposito LQ, Harris E, Burns K, Demedis J, Hoefgen H, Mertens A, Klosky JL. Risk for Unplanned Pregnancy Among Survivors of Childhood Cancer. Pediatr Blood Cancer. 2025 Jun; 72(6):e31653. PMID: 40098260.
      View in: PubMed
    8. Ross WL, Santiago-Rivera Y, Tan MT, Roy MM, Bryant S, Appel BE, Casillas J, Demedis J, Smitherman AB, Horwitz LI, Hurtado-de-Mendoza A, Mendoza JA, Santacroce SJ, Kadan-Lottick NS. Design and methods of a multi-level intervention to improve adherence to childhood cancer survivorship care by partnering with primary care providers: The BRIDGES randomized controlled trial. Contemp Clin Trials. 2025 05; 152:107859. PMID: 39987960.
      View in: PubMed
    9. Slatnick LR, Hoogstra D, Fisher BT, Wolf J, Orgel E, Nessle CN, Patel PA, Miller TP, Wilkes J, Dupuis LL, Goode E, Jackson K, Willis DN, Elgarten C, Aftandilian C, Thompson J, Alexander S, Beauchemin MP, Belsky JA, Hess J, Prudowsky ZD, Guinipero T, Rossoff J, Demedis J, Walsh AM, Richards R, Choi DK, Dvorak CC, Esbenshade AJ. Prevention and Management of Infectious Complications in Pediatric Patients With Cancer: A Survey Assessment of Current Practices Across Children's Oncology Group Institutions. Pediatr Blood Cancer. 2025 Mar; 72(3):e31532. PMID: 39780366.
      View in: PubMed
    10. Dupuis LL, Vettese E, Grimes AC, Beauchemin MP, Klesges LM, Baggott C, Demedis J, Aftandilian C, Freyer DR, Crellin-Parsons N, Orgel E, Dickens D, Kelly KM, Kyono W, Walsh A, Sherani F, Cannone D, Orsey AD, King AA, Yu L, Woods-Swafford W, Bradfield SM, Roth ME, Esbenshade AJ, Caywood EH, Agarwal V, Nagasubramanian R, Tomlinson GA, Sung L. Symptom Screening Linked to Care Pathways for Pediatric Patients With Cancer: A Randomized Clinical Trial. JAMA. 2024 12 17; 332(23):1981-1991. PMID: 39535768.
      View in: PubMed
    11. Demedis J, Reedy J, Miller K, Hu J, Klosky JL, Dorsey Holliman B, Peterson PN, Chow EJ, Studts C. Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol. PLoS One. 2024; 19(7):e0305677. PMID: 39038011.
      View in: PubMed
    12. Goodspeed A, Bodlak A, Duffy AB, Nelson-Taylor S, Oike N, Porfilio T, Shirai R, Walker D, Treece A, Black J, Donaldson N, Cost C, Garrington T, Greffe B, Luna-Fineman S, Demedis J, Lake J, Danis E, Verneris M, Adams DL, Hayashi M. Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells. bioRxiv. 2024 Jun 20. PMID: 38293103.
      View in: PubMed
    13. Demedis J, Reedy J, Miller K, Hu J, Klosky JL, Holliman BD, Peterson PN, Chow EJ, Studts C. Testing effectiveness and implementation of a standardized approach to sexual dysfunction screening among adolescent and young adult-aged survivors of childhood cancer: A type I hybrid, mixed methods trial protocol: Effectiveness of sexual dysfunction screening among AYA cancer survivors: a study protocol. medRxiv. 2024 Jun 06. PMID: 38883789.
      View in: PubMed
    14. Demedis J, Bingen K, Cherven B, Frederick NN, Freyer DR, Levine J, Bhutada JS, Quinn GP, Bober SL, DuVall AS. Development of a Patient-Reported Sexual Health Outcomes Battery for Use in Adolescent and Young Adult Cancer Clinical Trials. J Adolesc Young Adult Oncol. 2024 06; 13(3):369-373. PMID: 38569163.
      View in: PubMed
    15. Demedis J, Reedy J, Chow EJ, Dorsey Holliman B, Peterson PN, Studts CR. Provider perspectives and recommendations on standardized sexual function screening intervention in adolescent/young adult oncology patients. Pediatr Blood Cancer. 2024 Apr; 71(4):e30872. PMID: 38233999.
      View in: PubMed
    16. De Castro GC, Slatnick LR, Shannon M, Zhao Z, Jackson K, Smith CM, Whitehurst D, Elliott C, Clark CC, Scott HF, Friedman DL, Demedis J, Esbenshade AJ. Impact of Time-to-Antibiotic Delivery in Pediatric Patients With Cancer Presenting With Febrile Neutropenia. JCO Oncol Pract. 2024 02; 20(2):228-238. PMID: 38127868.
      View in: PubMed
    17. Zhao Z, Patel PA, Slatnick L, Sitthi-Amorn A, Bielamowicz KJ, Nunez FA, Walsh AM, Hess J, Rossoff J, Elgarten C, Myers R, Saab R, Basbous M, Mccormick M, Aftandilian C, Richards R, Nessle CN, Tribble AC, Sheth Bhutada JK, Coven SL, Runco D, Wilkes J, Gurunathan A, Guinipero T, Belsky JA, Lee K, Wong V, Malhotra M, Armstrong A, Jerkins LP, Cross SJ, Fisher L, Stein MT, Wu NL, Yi T, Orgel E, Haeusler GM, Wolf J, Demedis JM, Miller TP, Esbenshade AJ. Prospective External Validation of the Esbenshade Vanderbilt Models Accurately Predicts Bloodstream Infection Risk in Febrile Non-Neutropenic Children With Cancer. J Clin Oncol. 2024 03 01; 42(7):832-841. PMID: 38060973.
      View in: PubMed
    18. Meier KM, Linton A, Baldes C, Demedis J, Cost NG. Peripubertal Presentation of Metastatic Testicular Mixed, Nonseminomatous Germ Cell Tumor. Urology. 2024 02; 184:e239-e242. PMID: 37956765.
      View in: PubMed
    19. Smolik S, Miller AL, Mong DA, Trenbeath Z, Miller KR, Cost C, Demedis J. Incidence and Risk Factors for Brown Adipose Tissue Uptake in PET Imaging in Pediatric Patients. J Pediatr Hematol Oncol. 2024 01 01; 46(1):e60-e64. PMID: 37910816.
      View in: PubMed
    20. Cherven BO, Demedis J, Frederick NN. Sexual Health in Adolescents and Young Adults With Cancer. J Clin Oncol. 2024 02 20; 42(6):717-724. PMID: 37856773.
      View in: PubMed
    21. Burns K, Phillips C, Brannigan R, Franklin A, Howell J, Schmidt D, Sopfe J, Appiah LC, Anazodo A. Male pediatric, adolescent, and young adult reproductive survivorship. Pediatr Blood Cancer. 2023 09; 70 Suppl 5:e28823. PMID: 37381156.
      View in: PubMed
    22. Cherven B, Ivankova NV, Spencer JB, Fitzpatrick AM, Burns KC, Demedis J, Hoefgen HR, Mertens AC, Klosky JL. Examining decisional needs and contextual factors influencing fertility status assessment among young female survivors of childhood cancer: A sequential mixed methods study protocol. PLoS One. 2023; 18(6):e0286511. PMID: 37315007.
      View in: PubMed
    23. Cai CR, Cornelius S, Demedis J, Hagen AM, Abbey-Lambertz M, Armstrong GT, Oeffinger KC, Syrjala KL, Taylor SL, Yi JC, Chow EJ. Experiences of adult survivors of childhood cancer in a randomized cardiovascular health promotion trial: a qualitative report from the Childhood Cancer Survivor Study. J Cancer Surviv. 2024 Oct; 18(5):1665-1673. PMID: 37253902.
      View in: PubMed
    24. Meier KM, Demedis J, Edwards M, Cost NG. Vaginal Rhabdoid Tumor Presenting as Prenatal Lower Urinary Tract Obstruction and Vaginal Mass. Urology. 2023 07; 177:175-177. PMID: 36736915.
      View in: PubMed
    25. Demedis J, Scarbro S, Suresh K, Maloney K, Forlenza GP. Hyperglycemia and Other Glycemic Measures Throughout Therapy for Pediatric Acute Lymphoblastic Leukemia and Lymphoma. J Pediatr Hematol Oncol. 2023 03 01; 45(2):e154-e160. PMID: 36715999.
      View in: PubMed
    26. Cho S, Vigers T, Pyle L, Franklin A, Sopfe J, Jeney F, Forlenza G. Composite Metric of Glycemic Control Q-Score Is Elevated in Pediatric and Adolescent/Young Adult Hematopoietic Stem Cell Transplant Recipients. Diabetes Technol Ther. 2023 02; 25(2):116-121. PMID: 36511871.
      View in: PubMed
    27. Reinman L, Coons HL, Sopfe J, Casey R. Psychosexual Care of Adolescent and Young Adult (AYA) Cancer Survivors. Children (Basel). 2021 Nov 16; 8(11). PMID: 34828771.
      View in: PubMed
    28. Sopfe J, Marsh R, Frederick NN, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Adolescent and young adult childhood cancer survivors' preferences for screening and education of sexual function. Pediatr Blood Cancer. 2021 12; 68(12):e29229. PMID: 34245209.
      View in: PubMed
    29. Macaruso N, Campbell K, Cost C, Sopfe J. Provider Documentation of Tinnitus in Childhood Cancer Survivors. J Pediatr Hematol Oncol. 2021 07 01; 43(5):e642-e647. PMID: 33065711.
      View in: PubMed
    30. Sopfe J, Pettigrew J, Afghahi A, Appiah LC, Coons HL. Interventions to Improve Sexual Health in Women Living with and Surviving Cancer: Review and Recommendations. Cancers (Basel). 2021 Jun 24; 13(13). PMID: 34202477.
      View in: PubMed
    31. Bodlak A, Chang K, Channel J, Treece AL, Donaldson N, Cost CR, Garrington TP, Greffe B, Luna-Fineman S, Sopfe J, Loeb DM, Hayashi M. Circulating Plasma Tumor DNA Is Superior to Plasma Tumor RNA Detection in Ewing Sarcoma Patients: ptDNA and ptRNA in Ewing Sarcoma. J Mol Diagn. 2021 07; 23(7):872-881. PMID: 33887462.
      View in: PubMed
    32. Sopfe J, Greffe B, Treece AL. Metastatic NUT Midline Carcinoma Treated With Aggressive Neoadjuvant Chemotherapy, Radiation, and Resection: A Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2021 01; 43(1):e73-e75. PMID: 32555032.
      View in: PubMed
    33. Sopfe J, Marsh R, Ziniel SI, Klosky JL, Chow EJ, Dorsey Holliman B, Peterson PN. Evaluation of the v2.0 Brief Profiles for Sexual Function and Satisfaction PROMIS in Adolescent and Young Adult Childhood Cancer Survivors. J Adolesc Young Adult Oncol. 2021 08; 10(4):418-424. PMID: 33136468.
      View in: PubMed
    34. Sopfe J, Campbell K, Keating AK, Pyle L, Liu AK, Verneris MR, Giller RH, Forlenza GP. Glycemic variability is associated with poor outcomes in pediatric hematopoietic stem cell transplant patients. Pediatr Blood Cancer. 2020 11; 67(11):e28626. PMID: 33480469.
      View in: PubMed
    35. Sopfe J, Gupta A, Appiah LC, Chow EJ, Peterson PN. Sexual Dysfunction in Adolescent and Young Adult Survivors of Childhood Cancer: Presentation, Risk Factors, and Evaluation of an Underdiagnosed Late Effect: A Narrative Review. J Adolesc Young Adult Oncol. 2020 10; 9(5):549-560. PMID: 32380878.
      View in: PubMed
    36. Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 10; 22(10):727-733. PMID: 32105513.
      View in: PubMed
    37. Grimes A, Mohamed A, Sopfe J, Hill R, Lynch J. Hyperglycemia During Childhood Cancer Therapy: Incidence, Implications, and Impact on Outcomes. J Natl Cancer Inst Monogr. 2019 09 01; 2019(54):132-138. PMID: 31532529.
      View in: PubMed
    38. Phillips CA, Razzaghi H, Aglio T, McNeil MJ, Salvesen-Quinn M, Sopfe J, Wilkes JJ, Forrest CB, Bailey LC. Development and evaluation of a computable phenotype to identify pediatric patients with leukemia and lymphoma treated with chemotherapy using electronic health record data. Pediatr Blood Cancer. 2019 09; 66(9):e27876. PMID: 31207054.
      View in: PubMed
    39. Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 02 12; 3(3):350-359. PMID: 30718242.
      View in: PubMed
    40. Sopfe J, Endres A, Campbell K, Hayes K, Trout AT, Liang X, Lorsbach R, O'Brien MM, Cost CR. Castleman disease in pediatrics: Insights on presentation, treatment, and outcomes from a two-site retrospective cohort study. Pediatr Blood Cancer. 2019 05; 66(5):e27613. PMID: 30680887.
      View in: PubMed
    41. Faulk KE, Sopfe JM, Campbell K, Liptzin DR, Liu AK, Franklin ARK, Cost CR. Pulmonary toxicity in paediatric patients with relapsed or refractory Hodgkin lymphoma receiving brentuximab vedotin. Br J Haematol. 2018 10; 183(2):251-256. PMID: 30198571.
      View in: PubMed
    42. Zastoupil L, McIntosh A, Sopfe J, Burrows J, Kraynik J, Lane L, Hanson J, Seltz LB. Positive Impact of Transition From Noon Conference to Academic Half Day in a Pediatric Residency Program. Acad Pediatr. 2017 May - Jun; 17(4):436-442. PMID: 28130128.
      View in: PubMed
    43. Esbenshade AJ, Sopfe J, Zhao Z, Li Z, Campbell K, Simmons JH, Friedman DL. Screening for vitamin D insufficiency in pediatric cancer survivors. Pediatr Blood Cancer. 2014 Apr; 61(4):723-8. PMID: 24194420.
      View in: PubMed
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