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Connection

Alexander Horswill to Mice

This is a "connection" page, showing publications Alexander Horswill has written about Mice.

 
Connection Strength
  
 
 
1.490
  
  1. Bhattacharya M, Scherr TD, Lister J, Kielian T, Horswill AR. Extracellular adherence proteins reduce matrix porosity and enhance Staphylococcus aureus biofilm survival during prosthetic joint infection. Infect Immun. 2025 04 08; 93(4):e0008625.
    View in: PubMed
    Score: 0.069
  2. Enroth TJ, Severn MM, Costa FG, Bovee AR, Wilkening RV, Nguyen DT, Langouët-Astrié C, Horswill AR. Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin. Infect Immun. 2025 04 08; 93(4):e0002825.
    View in: PubMed
    Score: 0.069
  3. Lyon LM, Marroquin SM, Thorstenson JC, Joyce LR, Fuentes EJ, Doran KS, Horswill AR. Genome-wide mutagenesis identifies factors involved in MRSA vaginal colonization. Cell Rep. 2025 Mar 25; 44(3):115421.
    View in: PubMed
    Score: 0.069
  4. Crosby HA, Keim K, Kwiecinski JM, Langouët-Astrié CJ, Oshima K, LaRivière WB, Schmidt EP, Horswill AR. Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG. mBio. 2024 Apr 10; 15(4):e0348323.
    View in: PubMed
    Score: 0.065
  5. Wilkening RV, Langouët-Astrié C, Severn MM, Federle MJ, Horswill AR. Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model. Cell Rep. 2023 11 28; 42(11):113332.
    View in: PubMed
    Score: 0.063
  6. Jenul C, Keim KC, Jens JN, Zeiler MJ, Schilcher K, Schurr MJ, Melander C, Phelan VV, Horswill AR. Pyochelin biotransformation by Staphylococcus aureus shapes bacterial competition with Pseudomonas aeruginosa in polymicrobial infections. Cell Rep. 2023 06 27; 42(6):112540.
    View in: PubMed
    Score: 0.061
  7. Bhattacharya M, Horswill AR. Breaking bad. J Exp Med. 2023 06 05; 220(6).
    View in: PubMed
    Score: 0.061
  8. Lyon LM, Doran KS, Horswill AR. Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract. Infect Immun. 2023 01 24; 91(1):e0046022.
    View in: PubMed
    Score: 0.059
  9. Kwiecinski JM, Jelani DA, Fuentes EJ, Horswill AR. Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence. Antimicrob Agents Chemother. 2022 07 19; 66(7):e0018722.
    View in: PubMed
    Score: 0.057
  10. Severn MM, Williams MR, Shahbandi A, Bunch ZL, Lyon LM, Nguyen A, Zaramela LS, Todd DA, Zengler K, Cech NB, Gallo RL, Horswill AR. The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens. mBio. 2022 06 28; 13(3):e0093022.
    View in: PubMed
    Score: 0.057
  11. Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
    View in: PubMed
    Score: 0.054
  12. Brown MM, Kwiecinski JM, Cruz LM, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel Peptide from Commensal Staphylococcus simulans Blocks Methicillin-Resistant Staphylococcus aureus Quorum Sensing and Protects Host Skin from Damage. Antimicrob Agents Chemother. 2020 05 21; 64(6).
    View in: PubMed
    Score: 0.049
  13. Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. mSphere. 2019 08 14; 4(4).
    View in: PubMed
    Score: 0.047
  14. Kwiecinski JM, Crosby HA, Valotteau C, Hippensteel JA, Nayak MK, Chauhan AK, Schmidt EP, Dufrêne YF, Horswill AR. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade. PLoS Pathog. 2019 05; 15(5):e1007800.
    View in: PubMed
    Score: 0.046
  15. Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Rep. 2019 04 02; 27(1):187-198.e6.
    View in: PubMed
    Score: 0.046
  16. Paharik AE, Parlet CP, Chung N, Todd DA, Rodriguez EI, Van Dyke MJ, Cech NB, Horswill AR. Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing. Cell Host Microbe. 2017 Dec 13; 22(6):746-756.e5.
    View in: PubMed
    Score: 0.042
  17. Ibberson CB, Parlet CP, Kwiecinski J, Crosby HA, Meyerholz DK, Horswill AR. Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection. Infect Immun. 2016 06; 84(6):1917-1929.
    View in: PubMed
    Score: 0.038
  18. Quave CL, Lyles JT, Kavanaugh JS, Nelson K, Parlet CP, Crosby HA, Heilmann KP, Horswill AR. Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance. PLoS One. 2015; 10(8):e0136486.
    View in: PubMed
    Score: 0.036
  19. Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Mol Microbiol. 2015 Apr; 96(2):388-404.
    View in: PubMed
    Score: 0.034
  20. Ibberson CB, Jones CL, Singh S, Wise MC, Hart ME, Zurawski DV, Horswill AR. Staphylococcus aureus hyaluronidase is a CodY-regulated virulence factor. Infect Immun. 2014 Oct; 82(10):4253-64.
    View in: PubMed
    Score: 0.033
  21. Kiedrowski MR, Crosby HA, Hernandez FJ, Malone CL, McNamara JO, Horswill AR. Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease. PLoS One. 2014; 9(4):e95574.
    View in: PubMed
    Score: 0.032
  22. Horswill AR, Nauseef WM. Host interception of bacterial communication signals. Cell Host Microbe. 2008 Dec 11; 4(6):507-9.
    View in: PubMed
    Score: 0.022
  23. Tamkin E, Lorenz BP, McCarty A, Fulte S, Eisenmesser E, Horswill AR, Clark SE. Airway Corynebacterium interfere with Streptococcus pneumoniae and Staphylococcus aureus infection and express secreted factors selectively targeting each pathogen. Infect Immun. 2025 02 18; 93(2):e0044524.
    View in: PubMed
    Score: 0.017
  24. Zehr EP, Erzen CL, Oshima K, Langouet-Astrie CJ, LaRiviere WB, Shi D, Zhang F, McCollister BD, Windham SL, Rizzo AN, Bastarache JA, Horswill AR, Schmidt EP, Kwiecinski JM, Colbert JF. Bacterial pneumonia-induced shedding of epithelial heparan sulfate inhibits the bactericidal activity of cathelicidin in a murine model. Am J Physiol Lung Cell Mol Physiol. 2024 02 01; 326(2):L206-L212.
    View in: PubMed
    Score: 0.016
  25. Deng L, Costa F, Blake KJ, Choi S, Chandrabalan A, Yousuf MS, Shiers S, Dubreuil D, Vega-Mendoza D, Rolland C, Deraison C, Voisin T, Bagood MD, Wesemann L, Frey AM, Palumbo JS, Wainger BJ, Gallo RL, Leyva-Castillo JM, Vergnolle N, Price TJ, Ramachandran R, Horswill AR, Chiu IM. S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Cell. 2023 11 22; 186(24):5375-5393.e25.
    View in: PubMed
    Score: 0.016
  26. Williams MR, Bagood MD, Enroth TJ, Bunch ZL, Jiang N, Liu E, Almoughrabie S, Khalil S, Li F, Brinton S, Cech NB, Horswill AR, Gallo RL. Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins. Cell Rep. 2023 09 26; 42(9):113024.
    View in: PubMed
    Score: 0.015
  27. Akbari MS, Keogh RA, Radin JN, Sanchez-Rosario Y, Johnson MDL, Horswill AR, Kehl-Fie TE, Burcham LR, Doran KS. The impact of nutritional immunity on Group B streptococcal pathogenesis during wound infection. mBio. 2023 08 31; 14(4):e0030423.
    View in: PubMed
    Score: 0.015
  28. Colbert JF, Kirsch JM, Erzen CL, Langouët-Astrié CJ, Thompson GE, McMurtry SA, Kofonow JM, Robertson CE, Kovacs EJ, Sullivan RC, Hippensteel JA, Sawant NV, De Nisco NJ, McCollister BD, Schwartz RS, Horswill AR, Frank DN, Duerkop BA, Schmidt EP. Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity. mBio. 2023 06 27; 14(3):e0005223.
    View in: PubMed
    Score: 0.015
  29. Hinman KD, Laforce-Nesbitt SS, Cohen JT, Mundy M, Bliss JM, Horswill AR, Lefort CT. Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo. Front Immunol. 2023; 14:1089111.
    View in: PubMed
    Score: 0.015
  30. Langouët-Astrié C, Oshima K, McMurtry SA, Yang Y, Kwiecinski JM, LaRivière WB, Kavanaugh JS, Zakharevich I, Hansen KC, Shi D, Zhang F, Boguslawski KM, Perelman SS, Su G, Torres VJ, Liu J, Horswill AR, Schmidt EP. The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia. Cell Rep. 2022 11 29; 41(9):111721.
    View in: PubMed
    Score: 0.015
  31. de Vor L, van Dijk B, van Kessel K, Kavanaugh JS, de Haas C, Aerts PC, Viveen MC, Boel EC, Fluit AC, Kwiecinski JM, Krijger GC, Ramakers RM, Beekman FJ, Dadachova E, Lam MG, Vogely HC, van der Wal BC, van Strijp JA, Horswill AR, Weinans H, Rooijakkers SH. Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm. Elife. 2022 01 06; 11.
    View in: PubMed
    Score: 0.014
  32. Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI Insight. 2021 11 08; 6(21).
    View in: PubMed
    Score: 0.014
  33. Nakamura K, Williams MR, Kwiecinski JM, Horswill AR, Gallo RL. Staphylococcus aureus Enters Hair Follicles Using Triacylglycerol Lipases Preserved through the Genus Staphylococcus. J Invest Dermatol. 2021 08; 141(8):2094-2097.
    View in: PubMed
    Score: 0.013
  34. Cau L, Williams MR, Butcher AM, Nakatsuji T, Kavanaugh JS, Cheng JY, Shafiq F, Higbee K, Hata TR, Horswill AR, Gallo RL. Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis. J Allergy Clin Immunol. 2021 03; 147(3):955-966.e16.
    View in: PubMed
    Score: 0.012
  35. Deng L, Schilcher K, Burcham LR, Kwiecinski JM, Johnson PM, Head SR, Heinrichs DE, Horswill AR, Doran KS. Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization. mBio. 2019 12 24; 10(6).
    View in: PubMed
    Score: 0.012
  36. Miller RJ, Crosby HA, Schilcher K, Wang Y, Ortines RV, Mazhar M, Dikeman DA, Pinsker BL, Brown ID, Joyce DP, Zhang J, Archer NK, Liu H, Alphonse MP, Czupryna J, Anderson WR, Bernthal NM, Fortuno-Miranda L, Bulte JWM, Francis KP, Horswill AR, Miller LS. Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections. Sci Rep. 2019 11 13; 9(1):16663.
    View in: PubMed
    Score: 0.012
  37. Borbón TY, Scorza BM, Clay GM, Lima Nobre de Queiroz F, Sariol AJ, Bowen JL, Chen Y, Zhanbolat B, Parlet CP, Valadares DG, Cassel SL, Nauseef WM, Horswill AR, Sutterwala FS, Wilson ME. Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A. PLoS Negl Trop Dis. 2019 05; 13(5):e0007247.
    View in: PubMed
    Score: 0.012
  38. Urbano R, Karlinsey JE, Libby SJ, Doulias PT, Ischiropoulos H, Warheit-Niemi HI, Liggitt DH, Horswill AR, Fang FC. Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Cell Host Microbe. 2018 05 09; 23(5):594-606.e7.
    View in: PubMed
    Score: 0.011
  39. Todd DA, Parlet CP, Crosby HA, Malone CL, Heilmann KP, Horswill AR, Cech NB. Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections. Antimicrob Agents Chemother. 2017 08; 61(8).
    View in: PubMed
    Score: 0.010
  40. Muhs A, Lyles JT, Parlet CP, Nelson K, Kavanaugh JS, Horswill AR, Quave CL. Virulence Inhibitors from Brazilian Peppertree Block Quorum Sensing and Abate Dermonecrosis in Skin Infection Models. Sci Rep. 2017 02 10; 7:42275.
    View in: PubMed
    Score: 0.010
  41. Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. mBio. 2015 Aug 25; 6(4).
    View in: PubMed
    Score: 0.009
  42. Decker R, Burdelski C, Zobiak M, Büttner H, Franke G, Christner M, Saß K, Zobiak B, Henke HA, Horswill AR, Bischoff M, Bur S, Hartmann T, Schaeffer CR, Fey PD, Rohde H. An 18 kDa scaffold protein is critical for Staphylococcus epidermidis biofilm formation. PLoS Pathog. 2015 Mar; 11(3):e1004735.
    View in: PubMed
    Score: 0.009
  43. Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ?-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrob Agents Chemother. 2015 Apr; 59(4):2223-35.
    View in: PubMed
    Score: 0.009
  44. Parlet CP, Kavanaugh JS, Horswill AR, Schlueter AJ. Chronic ethanol feeding increases the severity of Staphylococcus aureus skin infections by altering local host defenses. J Leukoc Biol. 2015 Apr; 97(4):769-78.
    View in: PubMed
    Score: 0.009
  45. Hernandez FJ, Huang L, Olson ME, Powers KM, Hernandez LI, Meyerholz DK, Thedens DR, Behlke MA, Horswill AR, McNamara JO. Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nat Med. 2014 Mar; 20(3):301-6.
    View in: PubMed
    Score: 0.008
  46. White MJ, Boyd JM, Horswill AR, Nauseef WM. Phosphatidylinositol-specific phospholipase C contributes to survival of Staphylococcus aureus USA300 in human blood and neutrophils. Infect Immun. 2014 Apr; 82(4):1559-71.
    View in: PubMed
    Score: 0.008
  47. Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation. PLoS One. 2013; 8(12):e84089.
    View in: PubMed
    Score: 0.008
  48. Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 2013 Sep 05; 501(7465):52-7.
    View in: PubMed
    Score: 0.008
  49. Zurek OW, Nygaard TK, Watkins RL, Pallister KB, Torres VJ, Horswill AR, Voyich JM. The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus. J Innate Immun. 2014; 6(1):21-30.
    View in: PubMed
    Score: 0.008
  50. Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. PLoS Pathog. 2013 Feb; 9(2):e1003166.
    View in: PubMed
    Score: 0.007
  51. Olson ME, Nygaard TK, Ackermann L, Watkins RL, Zurek OW, Pallister KB, Griffith S, Kiedrowski MR, Flack CE, Kavanaugh JS, Kreiswirth BN, Horswill AR, Voyich JM. Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor. Infect Immun. 2013 Apr; 81(4):1316-24.
    View in: PubMed
    Score: 0.007
  52. Kolar SL, Ibarra JA, Rivera FE, Mootz JM, Davenport JE, Stevens SM, Horswill AR, Shaw LN. Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability. Microbiologyopen. 2013 Feb; 2(1):18-34.
    View in: PubMed
    Score: 0.007
  53. Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96.
    View in: PubMed
    Score: 0.007
  54. Laarman AJ, Mijnheer G, Mootz JM, van Rooijen WJ, Ruyken M, Malone CL, Heezius EC, Ward R, Milligan G, van Strijp JA, de Haas CJ, Horswill AR, van Kessel KP, Rooijakkers SH. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J. 2012 Aug 29; 31(17):3607-19.
    View in: PubMed
    Score: 0.007
  55. Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98.
    View in: PubMed
    Score: 0.007
  56. Benson MA, Lilo S, Wasserman GA, Thoendel M, Smith A, Horswill AR, Fraser J, Novick RP, Shopsin B, Torres VJ. Staphylococcus aureus regulates the expression and production of the staphylococcal superantigen-like secreted proteins in a Rot-dependent manner. Mol Microbiol. 2011 Aug; 81(3):659-75.
    View in: PubMed
    Score: 0.007
  57. Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, Williams SH, Engebretsen IL, Bayles KW, Horswill AR, Kielian T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J Immunol. 2011 Jun 01; 186(11):6585-96.
    View in: PubMed
    Score: 0.007
  58. Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, von Köckritz-Blickwede M. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J Innate Immun. 2010; 2(6):576-86.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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