Connection
Alexander Horswill to Bacterial Proteins
This is a "connection" page, showing publications Alexander Horswill has written about Bacterial Proteins.
|
|
Connection Strength |
|
 |
|
 |
|
11.517 |
|
|
|
-
Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
Score: 0.510
-
Schilcher K, Caesar LK, Cech NB, Horswill AR. Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus. mBio. 2020 04 14; 11(2).
Score: 0.466
-
Horswill AR, Gordon CP. Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator. J Med Chem. 2020 03 26; 63(6):2705-2730.
Score: 0.453
-
Crosby HA, Tiwari N, Kwiecinski JM, Xu Z, Dykstra A, Jenul C, Fuentes EJ, Horswill AR. The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA. Mol Microbiol. 2020 01; 113(1):103-122.
Score: 0.453
-
Kavanaugh JS, Flack CE, Lister J, Ricker EB, Ibberson CB, Jenul C, Moormeier DE, Delmain EA, Bayles KW, Horswill AR. Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix. mBio. 2019 06 25; 10(3).
Score: 0.441
-
Kwiecinski JM, Crosby HA, Valotteau C, Hippensteel JA, Nayak MK, Chauhan AK, Schmidt EP, Dufr?ne YF, Horswill AR. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade. PLoS Pathog. 2019 05; 15(5):e1007800.
Score: 0.438
-
Gordon CP, Olson SD, Lister JL, Kavanaugh JS, Horswill AR. Truncated Autoinducing Peptides as Antagonists of Staphylococcus lugdunensis Quorum Sensing. J Med Chem. 2016 10 13; 59(19):8879-8888.
Score: 0.364
-
Crosby HA, Schlievert PM, Merriman JA, King JM, Salgado-Pab?n W, Horswill AR. The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression. PLoS Pathog. 2016 05; 12(5):e1005604.
Score: 0.355
-
Quave CL, Lyles JT, Kavanaugh JS, Nelson K, Parlet CP, Crosby HA, Heilmann KP, Horswill AR. Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance. PLoS One. 2015; 10(8):e0136486.
Score: 0.338
-
Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Mol Microbiol. 2015 Apr; 96(2):388-404.
Score: 0.327
-
Ibberson CB, Jones CL, Singh S, Wise MC, Hart ME, Zurawski DV, Horswill AR. Staphylococcus aureus hyaluronidase is a CodY-regulated virulence factor. Infect Immun. 2014 Oct; 82(10):4253-64.
Score: 0.314
-
Olson ME, Todd DA, Schaeffer CR, Paharik AE, Van Dyke MJ, B?ttner H, Dunman PM, Rohde H, Cech NB, Fey PD, Horswill AR. Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization. J Bacteriol. 2014 Oct; 196(19):3482-93.
Score: 0.314
-
Kiedrowski MR, Crosby HA, Hernandez FJ, Malone CL, McNamara JO, Horswill AR. Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease. PLoS One. 2014; 9(4):e95574.
Score: 0.308
-
Walker JN, Crosby HA, Spaulding AR, Salgado-Pab?n W, Malone CL, Rosenthal CB, Schlievert PM, Boyd JM, Horswill AR. The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis. PLoS Pathog. 2013; 9(12):e1003819.
Score: 0.301
-
Olson ME, Horswill AR. Staphylococcus aureus osteomyelitis: bad to the bone. Cell Host Microbe. 2013 Jun 12; 13(6):629-31.
Score: 0.290
-
Thoendel M, Horswill AR. Random mutagenesis and topology analysis of the autoinducing peptide biosynthesis proteins in Staphylococcus aureus. Mol Microbiol. 2013 Jan; 87(2):318-37.
Score: 0.280
-
Kavanaugh JS, Gakhar L, Horswill AR. The structure of LsrB from Yersinia pestis complexed with autoinducer-2. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 01; 67(Pt 12):1501-5.
Score: 0.261
-
Kiedrowski MR, Kavanaugh JS, Malone CL, Mootz JM, Voyich JM, Smeltzer MS, Bayles KW, Horswill AR. Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus. PLoS One. 2011; 6(11):e26714.
Score: 0.260
-
Thoendel M, Horswill AR. Identification of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis. J Biol Chem. 2009 Aug 14; 284(33):21828-21838.
Score: 0.220
-
Lauderdale KJ, Boles BR, Cheung AL, Horswill AR. Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect Immun. 2009 Apr; 77(4):1623-35.
Score: 0.215
-
Horswill AR, Nauseef WM. Host interception of bacterial communication signals. Cell Host Microbe. 2008 Dec 11; 4(6):507-9.
Score: 0.213
-
Boles BR, Horswill AR. Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog. 2008 Apr 25; 4(4):e1000052.
Score: 0.203
-
Malone CL, Boles BR, Horswill AR. Biosynthesis of Staphylococcus aureus autoinducing peptides by using the synechocystis DnaB mini-intein. Appl Environ Microbiol. 2007 Oct; 73(19):6036-44.
Score: 0.194
-
Wilkening RV, Langou?t-Astri? C, Severn MM, Federle MJ, Horswill AR. Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model. Cell Rep. 2023 11 28; 42(11):113332.
Score: 0.149
-
Kwiecinski JM, Jelani DA, Fuentes EJ, Horswill AR. Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence. Antimicrob Agents Chemother. 2022 07 19; 66(7):e0018722.
Score: 0.136
-
Severn MM, Williams MR, Shahbandi A, Bunch ZL, Lyon LM, Nguyen A, Zaramela LS, Todd DA, Zengler K, Cech NB, Gallo RL, Horswill AR. The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens. mBio. 2022 06 28; 13(3):e0093022.
Score: 0.135
-
Horswill AR, Dudding AR, Escalante-Semerena JC. Studies of propionate toxicity in Salmonella enterica identify 2-methylcitrate as a potent inhibitor of cell growth. J Biol Chem. 2001 Jun 01; 276(22):19094-101.
Score: 0.124
-
Nakamura K, Williams MR, Kwiecinski JM, Horswill AR, Gallo RL. Staphylococcus aureus Enters Hair Follicles Using?Triacylglycerol Lipases Preserved through?the?Genus Staphylococcus. J Invest Dermatol. 2021 08; 141(8):2094-2097.
Score: 0.124
-
Schilcher K, Horswill AR. Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies. Microbiol Mol Biol Rev. 2020 08 19; 84(3).
Score: 0.119
-
Jones DD, Caesar LK, Pelzer CV, Crandall WJ, Jenul C, Todd DA, Horswill AR, Cech NB. Targeted and untargeted analysis of secondary metabolites to monitor growth and quorum sensing inhibition for methicillin-resistant Staphylococcus aureus (MRSA). J Microbiol Methods. 2020 09; 176:106000.
Score: 0.118
-
Cau L, Williams MR, Butcher AM, Nakatsuji T, Kavanaugh JS, Cheng JY, Shafiq F, Higbee K, Hata TR, Horswill AR, Gallo RL. Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis. J Allergy Clin Immunol. 2021 03; 147(3):955-966.e16.
Score: 0.118
-
Brown MM, Kwiecinski JM, Cruz LM, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel Peptide from Commensal Staphylococcus simulans Blocks Methicillin-Resistant Staphylococcus aureus Quorum Sensing and Protects Host Skin from Damage. Antimicrob Agents Chemother. 2020 05 21; 64(6).
Score: 0.117
-
DelMain EA, Moormeier DE, Endres JL, Hodges RE, Sadykov MR, Horswill AR, Bayles KW. Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS. mBio. 2020 01 14; 11(1).
Score: 0.115
-
Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. mSphere. 2019 08 14; 4(4).
Score: 0.111
-
Jenul C, Horswill AR. Regulation of Staphylococcus aureus Virulence. Microbiol Spectr. 2019 04 05; 7(2).
Score: 0.109
-
Paharik AE, Parlet CP, Chung N, Todd DA, Rodriguez EI, Van Dyke MJ, Cech NB, Horswill AR. Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing. Cell Host Microbe. 2017 Dec 13; 22(6):746-756.e5.
Score: 0.099
-
Todd DA, Parlet CP, Crosby HA, Malone CL, Heilmann KP, Horswill AR, Cech NB. Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections. Antimicrob Agents Chemother. 2017 08; 61(8).
Score: 0.097
-
Paharik AE, Kotasinska M, Both A, Hoang TN, B?ttner H, Roy P, Fey PD, Horswill AR, Rohde H. The metalloprotease SepA governs processing of accumulation-associated protein and shapes intercellular adhesive surface properties in Staphylococcus epidermidis. Mol Microbiol. 2017 03; 103(5):860-874.
Score: 0.093
-
Crosby HA, Kwiecinski J, Horswill AR. Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions. Adv Appl Microbiol. 2016; 96:1-41.
Score: 0.090
-
Todd DA, Zich DB, Ettefagh KA, Kavanaugh JS, Horswill AR, Cech NB. Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition. J Microbiol Methods. 2016 08; 127:89-94.
Score: 0.089
-
Yang T, Tal-Gan Y, Paharik AE, Horswill AR, Blackwell HE. Structure-Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation. ACS Chem Biol. 2016 07 15; 11(7):1982-91.
Score: 0.089
-
Britton ER, Ibberson CB, Horswill AR, Cech NB. A new mass spectrometry based bioassay for the direct assessment of hyaluronidase activity and inhibition. J Microbiol Methods. 2015 Dec; 119:163-7.
Score: 0.086
-
Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. mBio. 2015 Aug 25; 6(4).
Score: 0.085
-
Schaeffer CR, Woods KM, Longo GM, Kiedrowski MR, Paharik AE, B?ttner H, Christner M, Boissy RJ, Horswill AR, Rohde H, Fey PD. Accumulation-associated protein enhances Staphylococcus epidermidis biofilm formation under dynamic conditions and is required for infection in a rat catheter model. Infect Immun. 2015 Jan; 83(1):214-26.
Score: 0.080
-
Sully EK, Malachowa N, Elmore BO, Alexander SM, Femling JK, Gray BM, DeLeo FR, Otto M, Cheung AL, Edwards BS, Sklar LA, Horswill AR, Hall PR, Gresham HD. Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. PLoS Pathog. 2014 Jun; 10(6):e1004174.
Score: 0.078
-
Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation. PLoS One. 2013; 8(12):e84089.
Score: 0.075
-
Cech NB, Horswill AR. Small-molecule quorum quenchers to prevent Staphylococcus aureus infection. Future Microbiol. 2013 Dec; 8(12):1511-4.
Score: 0.075
-
Pang YY, Schwartz J, Bloomberg S, Boyd JM, Horswill AR, Nauseef WM. Methionine sulfoxide reductases protect against oxidative stress in Staphylococcus aureus encountering exogenous oxidants and human neutrophils. J Innate Immun. 2014; 6(3):353-64.
Score: 0.075
-
Zurek OW, Nygaard TK, Watkins RL, Pallister KB, Torres VJ, Horswill AR, Voyich JM. The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus. J Innate Immun. 2014; 6(1):21-30.
Score: 0.073
-
Mootz JM, Malone CL, Shaw LN, Horswill AR. Staphopains modulate Staphylococcus aureus biofilm integrity. Infect Immun. 2013 Sep; 81(9):3227-38.
Score: 0.073
-
Junio HA, Todd DA, Ettefagh KA, Ehrmann BM, Kavanaugh JS, Horswill AR, Cech NB. Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography-high resolving power mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jul 01; 930:7-12.
Score: 0.072
-
Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. PLoS Pathog. 2013 Feb; 9(2):e1003166.
Score: 0.071
-
Olson ME, King JM, Yahr TL, Horswill AR. Sialic acid catabolism in Staphylococcus aureus. J Bacteriol. 2013 Apr; 195(8):1779-88.
Score: 0.071
-
Olson ME, Nygaard TK, Ackermann L, Watkins RL, Zurek OW, Pallister KB, Griffith S, Kiedrowski MR, Flack CE, Kavanaugh JS, Kreiswirth BN, Horswill AR, Voyich JM. Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor. Infect Immun. 2013 Apr; 81(4):1316-24.
Score: 0.071
-
Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96.
Score: 0.069
-
Laarman AJ, Mijnheer G, Mootz JM, van Rooijen WJ, Ruyken M, Malone CL, Heezius EC, Ward R, Milligan G, van Strijp JA, de Haas CJ, Horswill AR, van Kessel KP, Rooijakkers SH. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J. 2012 Aug 29; 31(17):3607-19.
Score: 0.068
-
W?rmann ME, Reichmann NT, Malone CL, Horswill AR, Gr?ndling A. Proteolytic cleavage inactivates the Staphylococcus aureus lipoteichoic acid synthase. J Bacteriol. 2011 Oct; 193(19):5279-91.
Score: 0.064
-
Benson MA, Lilo S, Wasserman GA, Thoendel M, Smith A, Horswill AR, Fraser J, Novick RP, Shopsin B, Torres VJ. Staphylococcus aureus regulates the expression and production of the staphylococcal superantigen-like secreted proteins in a Rot-dependent manner. Mol Microbiol. 2011 Aug; 81(3):659-75.
Score: 0.063
-
Laarman AJ, Ruyken M, Malone CL, van Strijp JA, Horswill AR, Rooijakkers SH. Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion. J Immunol. 2011 Jun 01; 186(11):6445-53.
Score: 0.063
-
Thoendel M, Kavanaugh JS, Flack CE, Horswill AR. Peptide signaling in the staphylococci. Chem Rev. 2011 Jan 12; 111(1):117-51.
Score: 0.061
-
Pang YY, Schwartz J, Thoendel M, Ackermann LW, Horswill AR, Nauseef WM. agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils. J Innate Immun. 2010; 2(6):546-59.
Score: 0.060
-
Beenken KE, Mrak LN, Griffin LM, Zielinska AK, Shaw LN, Rice KC, Horswill AR, Bayles KW, Smeltzer MS. Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation. PLoS One. 2010 May 24; 5(5):e10790.
Score: 0.059
-
Boles BR, Thoendel M, Roth AJ, Horswill AR. Identification of genes involved in polysaccharide-independent Staphylococcus aureus biofilm formation. PLoS One. 2010 Apr 14; 5(4):e10146.
Score: 0.058
-
Kavanaugh JS, Thoendel M, Horswill AR. A role for type I signal peptidase in Staphylococcus aureus quorum sensing. Mol Microbiol. 2007 Aug; 65(3):780-98.
Score: 0.048
-
Cheng L, Naumann TA, Horswill AR, Hong SJ, Venters BJ, Tomsho JW, Benkovic SJ, Keiler KC. Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease. Protein Sci. 2007 Aug; 16(8):1535-42.
Score: 0.048
-
Lewis JA, Horswill AR, Schwem BE, Escalante-Semerena JC. The Tricarballylate utilization (tcuRABC) genes of Salmonella enterica serovar Typhimurium LT2. J Bacteriol. 2004 Mar; 186(6):1629-37.
Score: 0.038
-
Weig AW, O'Conner PM, Kwiecinski JM, Marciano OM, Nunag A, Gutierrez AT, Melander RJ, Horswill AR, Melander C. A structure activity relationship study of 3,4'-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus. Org Biomol Chem. 2023 04 26; 21(16):3373-3380.
Score: 0.036
-
Fonseca MV, Buan NR, Horswill AR, Rayment I, Escalante-Semerena JC. The ATP:Co(I)rrinoid adenosyltransferase (CobA) enzyme of Salmonella enterica requires the 2'-OH group of ATP for function and yields inorganic triphosphate as its reaction byproduct. J Biol Chem. 2002 Sep 06; 277(36):33127-31.
Score: 0.034
-
Roy P, Horswill AR, Fey PD. Glycan-Dependent Corneocyte Adherence of Staphylococcus epidermidis Mediated by the Lectin Subdomain of Aap. mBio. 2021 08 31; 12(4):e0290820.
Score: 0.032
-
Kwiecinski JM, Jacobsson G, Horswill AR, Josefsson E, Jin T. Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type. Infect Dis (Lond). 2019 06; 51(6):446-451.
Score: 0.027
-
Urbano R, Karlinsey JE, Libby SJ, Doulias PT, Ischiropoulos H, Warheit-Niemi HI, Liggitt DH, Horswill AR, Fang FC. Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Cell Host Microbe. 2018 05 09; 23(5):594-606.e7.
Score: 0.025
-
Nicholson TL, Brockmeier SL, Sukumar N, Paharik AE, Lister JL, Horswill AR, Kehrli ME, Loving CL, Shore SM, Deora R. The Bordetella Bps Polysaccharide Is Required for Biofilm Formation and Enhances Survival in the Lower Respiratory Tract of Swine. Infect Immun. 2017 08; 85(8).
Score: 0.024
-
Horswill AR, Escalante-Semerena JC. Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon. J Bacteriol. 1997 Feb; 179(3):928-40.
Score: 0.023
-
Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ?-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrob Agents Chemother. 2015 Apr; 59(4):2223-35.
Score: 0.020
-
Flack CE, Zurek OW, Meishery DD, Pallister KB, Malone CL, Horswill AR, Voyich JM. Differential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil-derived stimuli. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):E2037-45.
Score: 0.019
-
Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98.
Score: 0.017
-
Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. J Biol Chem. 2011 May 13; 286(19):17351-8.
Score: 0.016
-
Gulick AM, Starai VJ, Horswill AR, Homick KM, Escalante-Semerena JC. The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A. Biochemistry. 2003 Mar 18; 42(10):2866-73.
Score: 0.009
|
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
|